Dan Simionescu - Publications

Affiliations: 
Bioengineering Clemson University, Clemson, SC, United States 
Area:
Biomedical Engineering

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sinha D, Nagy-Mehesz A, Simionescu D, Mayer JE, Vyavahare N. Pentagalloyl Glucose-stabilized Decellularized Bovine Jugular Vein Valved Conduits as Pulmonary Conduit Replacement. Acta Biomaterialia. PMID 37619898 DOI: 10.1016/j.actbio.2023.08.036  0.366
2022 Wang B, Sierad LN, Mercuri JJ, Simionescu A, Simionescu DT, Williams LN, Vela R, Bajona P, Peltz M, Ramaswamy S, Hong Y, Liao J. Structural and biomechanical characterizations of acellular porcine mitral valve scaffolds: anterior leaflets, posterior leaflets, and chordae tendineae. Engineered Regeneration. 3: 374-386. PMID 38362305 DOI: 10.1016/j.engreg.2022.08.003  0.314
2021 Movileanu I, Harpa M, Al Hussein H, Harceaga L, Chertes A, Al Hussein H, Lutter G, Puehler T, Preda T, Sircuta C, Cotoi O, Nistor D, Man A, Cordos B, Deac R, ... ... Simionescu D, et al. Preclinical Testing of Living Tissue-Engineered Heart Valves for Pediatric Patients, Challenges and Opportunities. Frontiers in Cardiovascular Medicine. 8: 707892. PMID 34490371 DOI: 10.3389/fcvm.2021.707892  0.414
2020 Filippi A, Constantin A, Alexandru N, Voicu G, Constantinescu CA, Rebleanu D, Fenyo M, Simionescu D, Simionescu A, Manduteanu I, Georgescu A. Integrins α4β1 and αVβ3 are Reduced in Endothelial Progenitor Cells from Diabetic Dyslipidemic Mice and May Represent New Targets for Therapy in Aortic Valve Disease. Cell Transplantation. 29: 963689720946277. PMID 32841051 DOI: 10.1177/0963689720946277  0.312
2019 Lutter G, Dai H, Hansen JH, Frank D, Haneya A, Simionescu D, Cremer J, Puehler T. Transcatheter mitral valve replacement (TMVR): annular or apical fixation? Eurointervention : Journal of Europcr in Collaboration With the Working Group On Interventional Cardiology of the European Society of Cardiology. PMID 31793883 DOI: 10.4244/Eij-D-19-00614  0.306
2019 Hussein HA, Harpa M, Movileanu I, Hussein HA, Suciu H, Branzaniuc K, Simionescu D. Minimally Invasive Surgical Protocol for Adipose Derived Stem Cells Collection and Isolation - Ovine Model Revista De Chimie. 70: 1826-1828. DOI: 10.37358/Rc.19.5.7224  0.428
2019 Harpa M, Sircuta C, Cotoi OS, Man A, Deac R, Suciu H, Brinzaniuc K, Simionescu D. Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study Materiale Plastice. 57: 104-112. DOI: 10.37358/Mp.20.2.5356  0.389
2017 Movileanu L, Harpa M, Branzaniuc K, Suciu H, Cotoi OS, Olah P, Simionescu D. A Standardized Dissection Protocol to Generate Aortic Valvular Scaffolds from Porcine Hearts. Acta Medica Marisiensis. 63: 133-135. PMID 31080636 DOI: 10.1515/Amma-2017-0029  0.369
2017 Haupt J, Lutter G, Gorb SN, Simionescu DT, Frank D, Seiler J, Paur A, Haben I. Detergent-based decellularization strategy preserves macro- and microstructure of heart valves. Interactive Cardiovascular and Thoracic Surgery. PMID 29155942 DOI: 10.1093/icvts/ivx316  0.319
2017 Casco M, Olsen T, Herbst A, Evans G, Rothermel T, Pruett L, Simionescu D, Visconti R, Alexis F. Iron Oxide Nanoparticles Stimulates Extra-Cellular Matrix Production in Cellular Spheroids. Bioengineering (Basel, Switzerland). 4. PMID 28952483 DOI: 10.3390/Bioengineering4010004  0.354
2016 Harpa M, Movileanu I, Sierad L, Cotoi O, Suciu H, Preda T, Nistor D, Sircuta C, Brânzaniuc K, Deac R, Gurzu S, Harceaga L, Olah P, Simionescu D, Dandel M, et al. In Vivo Testing of Xenogeneic Acellular Aortic Valves Seeded with Stem Cells. Revista Romana De Medicina De Laborator. 24: 343-346. PMID 31098341 DOI: 10.1515/Rrlm-2016-0031  0.355
2016 Chow JP, Simionescu DT, Carter AL, Simionescu A. Immunomodulatory effects of adipose tissue-derived stem cells on elastin scaffold remodeling in diabetes. Tissue Engineering and Regenerative Medicine. 13: 701-712. PMID 30603451 DOI: 10.1007/S13770-016-0018-X  0.323
2016 Kennamer A, Sierad L, Pascal R, Rierson N, Albers C, Harpa M, Cotoi O, Harceaga L, Olah P, Terezia P, Simionescu A, Simionescu D. Bioreactor Conditioning of Valve Scaffolds Seeded Internally with Adult Stem Cells. Tissue Engineering and Regenerative Medicine. 13: 507-515. PMID 30337944 DOI: 10.1007/S13770-016-9114-1  0.384
2016 Deborde C, Simionescu DT, Wright C, Liao J, Sierad LN, Simionescu A. Stabilized collagen and elastin-based scaffolds for mitral valve tissue engineering. Tissue Engineering. Part A. PMID 27608885 DOI: 10.1089/ten.TEA.2016.0032  0.407
2015 Sierad LN, Shaw EL, Bina A, Brazile B, Rierson N, Patnaik SS, Kennamer A, Odum R, Cotoi O, Terezia P, Branzaniuc K, Smallwood H, Deac R, Egyed I, Pavai Z, ... ... Simionescu DT, et al. Functional Heart Valve Scaffolds Obtained by Complete Decellularization of Porcine Aortic Roots in a Novel Differential Pressure Gradient Perfusion System. Tissue Engineering. Part C, Methods. PMID 26467108 DOI: 10.1089/Ten.Tec.2015.0170  0.322
2015 Olsen TR, Mattix B, Casco M, Herbst A, Williams C, Tarasidis A, Simionescu D, Visconti RP, Alexis F. Manipulation of cellular spheroid composition and the effects on vascular tissue fusion. Acta Biomaterialia. 13: 188-98. PMID 25463485 DOI: 10.1016/J.Actbio.2014.11.024  0.447
2015 Harpa MM, Movileanu I, Sierad LN, Cotoi OS, Suciu H, Sircuta C, Preda T, Nistor D, Branzaniuc K, Deac R, Dandel M, Gurzu S, Harceaga L, Olah P, Simionescu A, ... Simionescu D, et al. Pulmonary heart valve replacement using stabilized acellular xenogeneic scaffolds; effects of seeding with autologous stem cells Revista Romana De Medicina De Laborator. 23: 415-430. DOI: 10.1515/Rrlm-2015-0046  0.439
2014 Pennel T, Fercana G, Bezuidenhout D, Simionescu A, Chuang TH, Zilla P, Simionescu D. The performance of cross-linked acellular arterial scaffolds as vascular grafts; pre-clinical testing in direct and isolation loop circulatory models Biomaterials. 35: 6311-6322. PMID 24816365 DOI: 10.1016/J.Biomaterials.2014.04.062  0.76
2014 Fercana G, Bowser D, Portilla M, Langan EM, Carsten CG, Cull DL, Sierad LN, Simionescu DT. Platform technologies for decellularization, tunic-specific cell seeding, and in vitro conditioning of extended length, small diameter vascular grafts. Tissue Engineering. Part C, Methods. 20: 1016-27. PMID 24749889 DOI: 10.1089/Ten.Tec.2014.0047  0.796
2014 Mercuri J, Addington C, Pascal R, Gill S, Simionescu D. Development and initial characterization of a chemically stabilized elastin-glycosaminoglycan-collagen composite shape-memory hydrogel for nucleus pulposus regeneration. Journal of Biomedical Materials Research. Part A. 102: 4380-93. PMID 24497431 DOI: 10.1002/Jbm.A.35104  0.728
2014 Olsen TR, Mattix B, Casco M, Herbst A, Williams C, Tarasidis A, Evans G, Jenkins L, McMahan CL, Simionescu D, Visconti RP, Alexis F. Processing cellular spheroids for histological examination Journal of Histotechnology. 37: 138-142. DOI: 10.1179/2046023614Y.0000000047  0.437
2014 Mercuri J, Addington C, Pascal R, Gill S, Simionescu D. Development and initial characterization of a chemically stabilized elastin-glycosaminoglycan-collagen composite shape-memory hydrogel for nucleus pulposus regeneration Journal of Biomedical Materials Research - Part A. 102: 4380-4393. DOI: 10.1002/jbm.a.35104  0.651
2013 Schulte JB, Simionescu A, Simionescu DT. The acellular myocardial flap: a novel extracellular matrix scaffold enriched with patent microvascular networks and biocompatible cell niches. Tissue Engineering. Part C, Methods. 19: 518-30. PMID 23151037 DOI: 10.1089/Ten.Tec.2012.0536  0.789
2013 Mercuri JJ, Patnaik S, Dion G, Gill SS, Liao J, Simionescu DT. Regenerative potential of decellularized porcine nucleus pulposus hydrogel scaffolds: stem cell differentiation, matrix remodeling, and biocompatibility studies. Tissue Engineering. Part A. 19: 952-66. PMID 23140227 DOI: 10.1089/Ten.Tea.2012.0088  0.722
2013 Chow JP, Simionescu DT, Warner H, Wang B, Patnaik SS, Liao J, Simionescu A. Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using matrix-binding polyphenol. Biomaterials. 34: 685-95. PMID 23103157 DOI: 10.1016/J.Biomaterials.2012.09.081  0.338
2013 Larrew T, Chow J, Schulte J, Simionescu D, Simionescu A. The roles of various metabolic enzymes in diabetic cardiomyopathy—in vivo and in vitro approach Cardiovascular Pathology. 22: e48. DOI: 10.1016/J.Carpath.2013.01.067  0.739
2013 Fercana G, Langan E, Wright C, Simionescu D. Development of living vascular grafts for peripheral bypass applications using a novel transmural perfusion bioreactor Cardiovascular Pathology. 22: e35. DOI: 10.1016/J.Carpath.2013.01.028  0.762
2013 Bezuidenhout D, Pennel T, Fercana G, Zilla P, Simionescu D. Evaluation of elastin-derived vascular grafts in a circulatory model Cardiovascular Pathology. 22: e32. DOI: 10.1016/J.Carpath.2013.01.018  0.775
2012 Simionescu DT, Chen J, Jaeggli M, Wang B, Liao J. Form Follows Function: Advances in Trilayered Structure Replication for Aortic Heart Valve Tissue Engineering. Journal of Healthcare Engineering. 3: 179-202. PMID 23355946 DOI: 10.1260/2040-2295.3.2.179  0.334
2012 Wang B, Tedder ME, Perez CE, Wang G, de Jongh Curry AL, To F, Elder SH, Williams LN, Simionescu DT, Liao J. Structural and biomechanical characterizations of porcine myocardial extracellular matrix. Journal of Materials Science. Materials in Medicine. 23: 1835-47. PMID 22584822 DOI: 10.1007/S10856-012-4660-0  0.315
2012 Simionescu D, Jaeggli M, Liao J, Simionescu A. Scaffolds and Stem Cells for Patient-Tailored Aortic Heart Valve Tissue Engineering Qscience Proceedings. 2012: 76. DOI: 10.5339/qproc.2012.heartvalve.4.76  0.333
2012 Mercuri JJ, Simionescu DT. Advances in tissue engineering approaches to treatment of intervertebral disc degeneration: Cells and polymeric scaffolds for nucleus pulposus regeneration Advances in Polymer Science. 247: 201-231. DOI: 10.1007/12_2011_149  0.716
2011 Simionescu A, Tedder ME, Chuang TH, Simionescu DT. Lectin and antibody-based histochemical techniques for cardiovascular tissue engineering. Journal of Histotechnology. 34: 20-28. PMID 25620822 DOI: 10.1179/014788811X12949268296040  0.659
2011 Simionescu A, Schulte JB, Fercana G, Simionescu DT. Inflammation in cardiovascular tissue engineering: the challenge to a promise: a minireview. International Journal of Inflammation. 2011: 958247. PMID 21755031 DOI: 10.4061/2011/958247  0.727
2011 Mercuri JJ, Gill SS, Simionescu DT. Novel tissue-derived biomimetic scaffold for regenerating the human nucleus pulposus. Journal of Biomedical Materials Research. Part A. 96: 422-35. PMID 21171162 DOI: 10.1002/Jbm.A.33001  0.685
2011 Tedder ME, Simionescu A, Chen J, Liao J, Simionescu DT. Assembly and testing of stem cell-seeded layered collagen constructs for heart valve tissue engineering. Tissue Engineering. Part A. 17: 25-36. PMID 20673028 DOI: 10.1089/Ten.Tea.2010.0138  0.385
2010 Sierad LN, Simionescu A, Albers C, Chen J, Maivelett J, Tedder ME, Liao J, Simionescu DT. Design and Testing of a Pulsatile Conditioning System for Dynamic Endothelialization of Polyphenol-Stabilized Tissue Engineered Heart Valves. Cardiovascular Engineering and Technology. 1: 138-153. PMID 21340043 DOI: 10.1007/S13239-010-0014-6  0.41
2010 Wang B, Borazjani A, Tahai M, Curry AL, Simionescu DT, Guan J, To F, Elder SH, Liao J. Fabrication of cardiac patch with decellularized porcine myocardial scaffold and bone marrow mononuclear cells. Journal of Biomedical Materials Research. Part A. 94: 1100-10. PMID 20694977 DOI: 10.1002/Jbm.A.32781  0.397
2010 Mercuri J, Gill S, Simionescu A, Simionescu D. Xenogenic Cues for Human Mesenchymal Stem Cell Differentiation towards a Nucleus Pulposus Cell-like Phenotype The Spine Journal. 10: S114-S115. DOI: 10.1016/J.Spinee.2010.07.301  0.651
2009 Chuang TH, Stabler C, Simionescu A, Simionescu DT. Polyphenol-stabilized tubular elastin scaffolds for tissue engineered vascular grafts. Tissue Engineering. Part A. 15: 2837-51. PMID 19254115 DOI: 10.1089/Ten.Tea.2008.0394  0.719
2009 Tedder ME, Liao J, Weed B, Stabler C, Zhang H, Simionescu A, Simionescu DT. Stabilized collagen scaffolds for heart valve tissue engineering. Tissue Engineering. Part A. 15: 1257-68. PMID 18928400 DOI: 10.1089/Ten.Tea.2008.0263  0.434
2008 Sierad LN, Simionescu D. In vitro testing of living aortic heart valves using a pulsatile bioreactor 2008 Proceedings of the 3rd Frontiers in Biomedical Devices Conference and Exhibition. 89-90. DOI: 10.1115/Biomed2008-38063  0.372
2007 Kurane A, Simionescu DT, Vyavahare NR. In vivo cellular repopulation of tubular elastin scaffolds mediated by basic fibroblast growth factor. Biomaterials. 28: 2830-8. PMID 17368531 DOI: 10.1016/J.Biomaterials.2007.02.031  0.405
2007 Mercuri JJ, Lovekamp JJ, Simionescu DT, Vyavahare NR. Glycosaminoglycan-targeted fixation for improved bioprosthetic heart valve stabilization. Biomaterials. 28: 496-503. PMID 17030363 DOI: 10.1016/J.Biomaterials.2006.09.005  0.719
2006 Isenburg JC, Karamchandani NV, Simionescu DT, Vyavahare NR. Structural requirements for stabilization of vascular elastin by polyphenolic tannins. Biomaterials. 27: 3645-51. PMID 16527345 DOI: 10.1016/j.biomaterials.2006.02.016  0.328
2006 Lovekamp JJ, Simionescu DT, Mercuri JJ, Zubiate B, Sacks MS, Vyavahare NR. Stability and function of glycosaminoglycans in porcine bioprosthetic heart valves. Biomaterials. 27: 1507-18. PMID 16144707 DOI: 10.1016/J.Biomaterials.2005.08.003  0.705
2006 Kasyanov V, Isenburg J, Draughn RA, Hazard S, Hodde J, Ozolanta I, Murovska M, Halkes SB, Vrasidas I, Liskamp RM, Pieters RJ, Simionescu D, Markwald RR, Mironov V. Tannic acid mimicking dendrimers as small intestine submucosa stabilizing nanomordants. Biomaterials. 27: 745-51. PMID 16102811 DOI: 10.1016/J.Biomaterials.2005.06.022  0.379
2006 Simionescu DT, Lu Q, Song Y, Lee JS, Rosenbalm TN, Kelley C, Vyavahare NR. Biocompatibility and remodeling potential of pure arterial elastin and collagen scaffolds. Biomaterials. 27: 702-13. PMID 16048731 DOI: 10.1016/J.Biomaterials.2005.06.013  0.469
2005 Isenburg JC, Simionescu DT, Vyavahare NR. Tannic acid treatment enhances biostability and reduces calcification of glutaraldehyde fixed aortic wall. Biomaterials. 26: 1237-45. PMID 15475053 DOI: 10.1016/j.biomaterials.2004.04.034  0.392
2004 Lu Q, Ganesan K, Simionescu DT, Vyavahare NR. Novel porous aortic elastin and collagen scaffolds for tissue engineering. Biomaterials. 25: 5227-37. PMID 15110474 DOI: 10.1016/J.Biomaterials.2003.12.019  0.41
2004 Bailey M, Pillarisetti S, Jones P, Xiao H, Simionescu D, Vyavahare N. Involvement of matrix metalloproteinases and tenascin-C in elastin calcification. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 13: 146-55. PMID 15081471 DOI: 10.1016/S1054-8807(04)00009-2  0.354
2004 Isenburg JC, Simionescu DT, Vyavahare NR. Elastin stabilization in cardiovascular implants: improved resistance to enzymatic degradation by treatment with tannic acid. Biomaterials. 25: 3293-302. PMID 14980424 DOI: 10.1016/j.biomaterials.2003.10.001  0.392
2003 Simionescu DT, Lovekamp JJ, Vyavahare NR. Extracellular matrix degrading enzymes are active in porcine stentless aortic bioprosthetic heart valves. Journal of Biomedical Materials Research. Part A. 66: 755-63. PMID 12926026 DOI: 10.1002/Jbm.A.10066  0.363
2003 Simionescu DT, Lovekamp JJ, Vyavahare NR. Degeneration of bioprosthetic heart valve cusp and wall tissues is initiated during tissue preparation: an ultrastructural study. The Journal of Heart Valve Disease. 12: 226-34. PMID 12701796  0.341
2001 Bracher M, Simionescu D, Simionescu A, Davies N, Human P, Zilla P. Matrix metalloproteinases and tissue valve degeneration Journal of Long-Term Effects of Medical Implants. 11: 221-230. PMID 11921665 DOI: 10.1615/Jlongtermeffmedimplants.V11.I34.90  0.366
2001 Movileanu I, Brinzaniuc K, Harpa MM, Cotoi OS, Preda T, Hussein HA, Suciu H, Simionescu D. Cryopreservation Increases Availability and Usability of Ovine Adipose-tissue Derived Stem Cells for Regenerative Medicine Search Revista De Chimie. 71: 178-184. DOI: 10.37358/Rc.20.3.7986  0.42
1996 Simionescu A, Simionescu D, Deac R. Biochemical pathways of tissue degeneration in bioprosthetic cardiac valves: The role of matrix metalloproteinases Asaio Journal. 42. PMID 8944942 DOI: 10.1097/00002480-199609000-00049  0.39
1996 Simionescu A, Simionescu DT, Deac RFP. Matrix metalloproteinases in the pathology of natural and bioprosthetic cardiac valves Cardiovascular Pathology. 5: 323-332. DOI: 10.1016/S1054-8807(96)00043-9  0.388
1995 Deac RFP, Simionescu D, Deac D. New evolution in mitral physiology and surgery: Mitral stentless pericardial valve The Annals of Thoracic Surgery. 60. PMID 7646203 DOI: 10.1016/0003-4975(95)00303-3  0.325
1993 Simionescu D, Simionescu A, Deac R. Detection of remnant proteolytic activities in unimplanted glutaraldehyde- treated bovine pericardium and explanted cardiac bioprostheses Journal of Biomedical Materials Research. 27: 821-829. PMID 8408112 DOI: 10.1002/Jbm.820270615  0.318
1993 Simionescu D, Simionescu A, Deac R. Mapping of glutaraldehyde-treated bovine pericardium and tissue selection for bioprosthetic heart valves Journal of Biomedical Materials Research. 27: 697-704. PMID 8408100 DOI: 10.1002/Jbm.820270602  0.312
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