Ronald A. Siegel - Publications

Affiliations: 
Biomedical Engineering University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biomedical Engineering, Chemical Engineering, Pharmacology

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Jain KMH, Hou HH, Siegel RA. An Artificial Gut/Absorption Simulator: Simultaneous Evaluation of Desupersaturation and Absorption from Ketoconazole Supersaturated Solutions. Journal of Pharmaceutical Sciences. PMID 36162494 DOI: 10.1016/j.xphs.2022.09.017  0.529
2022 Song S, Wang C, Zhang B, Sun CC, Lodge TP, Siegel RA. A Rheological Approach for Predicting Physical Stability of Amorphous Solid Dispersions. Journal of Pharmaceutical Sciences. PMID 36030843 DOI: 10.1016/j.xphs.2022.08.028  0.538
2022 Jain KMH, Hou HH, Siegel RA. Correction: An Artificial Gut/Absorption Simulator: Description, Modeling, and Validation Using Caffeine. The Aaps Journal. 24: 88. PMID 35970957 DOI: 10.1208/s12248-022-00740-y  0.425
2022 Meena Harish Jain K, Hou HH, Siegel RA. An Artificial Gut/Absorption Simulator: Description, Modeling, and Validation Using Caffeine. The Aaps Journal. 24: 87. PMID 35879480 DOI: 10.1208/s12248-022-00721-1  0.484
2021 Song S, Wang C, Wang S, Siegel RA, Sun CC. Efficient development of sorafenib tablets with improved oral bioavailability enabled by coprecipitated amorphous solid dispersion. International Journal of Pharmaceutics. 610: 121216. PMID 34688849 DOI: 10.1016/j.ijpharm.2021.121216  0.519
2020 Khandai S, Siegel RA, Jena SS. Probing the microenvironment of polyacrylamide hydrogel matrix using turbidity and fluorescence recovery after photobleaching: One versus Two phases Colloids and Surfaces a: Physicochemical and Engineering Aspects. 593: 124618. DOI: 10.1016/J.Colsurfa.2020.124618  0.3
2020 Siegel RA, Wu D. Examination of a Shannon entropy-like figure of merit for controlled release of drugs and other molecules Chemical Engineering Science. 212: 115315. DOI: 10.1016/J.Ces.2019.115315  0.318
2020 Hivechi A, Bahrami SH, Siegel RA, Milan PB, Amoupour M. In vitro and in vivo studies of biaxially electrospun poly(caprolactone)/gelatin nanofibers, reinforced with cellulose nanocrystals, for wound healing applications Cellulose. 27: 5179-5196. DOI: 10.1007/S10570-020-03106-9  0.306
2019 Rautiola D, Updyke JL, Nelson KM, Siegel RA. Diazepam prodrug stabilizes human aminopeptidase B during lyophilization. Molecular Pharmaceutics. PMID 31829605 DOI: 10.1021/Acs.Molpharmaceut.9B00880  0.326
2019 Hivechi A, Bahrami SH, Siegel RA. Drug release and biodegradability of electrospun cellulose nanocrystal reinforced polycaprolactone. Materials Science & Engineering. C, Materials For Biological Applications. 94: 929-937. PMID 30423781 DOI: 10.1016/J.Msec.2018.10.037  0.379
2018 Rautiola D, Cloyd JC, Siegel RA. Conversion of a soluble diazepam prodrug to supersaturated diazepam for rapid intranasal delivery: Kinetics and stability. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30227158 DOI: 10.1016/J.Jconrel.2018.09.013  0.36
2018 Siegel RA, Brown L, Edelman ER, Linhardt RJ. B'reshith. Journal of Controlled Release : Official Journal of the Controlled Release Society. 285: 252-257. PMID 30078756 DOI: 10.1016/j.jconrel.2018.07.005  0.48
2017 Kim A, Lee H, Jones CF, Mujumdar SK, Gu Y, Siegel RA. Swelling, Mechanics, and Thermal/Chemical Stability of Hydrogels Containing Phenylboronic Acid Side Chains. Gels (Basel, Switzerland). 4. PMID 30674779 DOI: 10.3390/Gels4010004  0.78
2017 Yao L, Calderer MC, Mori Y, Siegel RA. Rhythmomimetic Drug Delivery: Modeling, Analysis, and Numerical Simulation Siam Journal On Applied Mathematics. 77: 565-592. DOI: 10.1137/16M1067007  0.373
2016 Wang W, Siegel RA, Wang C. Nanocomposite Polymers with "Slimy" Surfaces that Refresh Following Abrasion. Acs Biomaterials Science & Engineering. 2: 180-187. PMID 33418631 DOI: 10.1021/acsbiomaterials.5b00182  0.331
2016 Siegel RA, Kirtane AR, Panyam J. Assessing the benefits of targeted drug delivery by nanocarriers: A partico/pharmacokinetic framework. Ieee Transactions On Bio-Medical Engineering. PMID 27913319 DOI: 10.1109/Tbme.2016.2632733  0.668
2016 Kapoor M, Cheryala N, Rautiola D, Georg GI, Cloyd JC, Siegel RA. Chirally Pure Prodrugs and Their Converting Enzymes Lead to High Supersaturation and Rapid Transcellular Permeation of Benzodiazepines. Journal of Pharmaceutical Sciences. PMID 27342435 DOI: 10.1016/J.Xphs.2016.05.011  0.305
2016 Wang W, Siegel RA, Wang C. Nanocomposite Polymers with "slimy" Surfaces that Refresh Following Abrasion Acs Biomaterial Science and Engineering. 2: 180-187. DOI: 10.1021/Acsbiomaterials.5B00182  0.417
2015 Siegel RA, Kapoor M, Cheryala N, Georg GI, Cloyd JC. Water-soluble benzodiazepine prodrug/enzyme combinations for intranasal rescue therapies. Epilepsy & Behavior : E&B. PMID 26115606 DOI: 10.1016/J.Yebeh.2015.05.004  0.31
2015 Kirtane AR, Siegel RA, Panyam J. A pharmacokinetic model for quantifying the effect of vascular permeability on the choice of drug carrier: a framework for personalized nanomedicine. Journal of Pharmaceutical Sciences. 104: 1174-86. PMID 25583443 DOI: 10.1002/Jps.24302  0.667
2014 Bhalla AS, Siegel RA. Mechanistic studies of an autonomously pulsing hydrogel/enzyme system for rhythmic hormone delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 196: 261-71. PMID 25450402 DOI: 10.1016/J.Jconrel.2014.10.019  0.61
2014 Siegel RA. Stimuli sensitive polymers and self regulated drug delivery systems: a very partial review. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 337-51. PMID 24984012 DOI: 10.1016/J.Jconrel.2014.06.035  0.331
2014 Kapoor M, Winter T, Lis L, Georg GI, Siegel RA. Rapid delivery of diazepam from supersaturated solutions prepared using prodrug/enzyme mixtures: toward intranasal treatment of seizure emergencies. The Aaps Journal. 16: 577-85. PMID 24700272 DOI: 10.1208/S12248-014-9596-5  0.348
2014 Song SH, Park JH, Chitnis G, Siegel RA, Ziaie B. A wireless chemical sensor featuring iron oxidenanoparticle-embedded hydrogels Sensors and Actuators, B: Chemical. 193: 925-930. DOI: 10.1016/J.Snb.2013.12.012  0.37
2013 Kapoor M, Siegel RA. Prodrug/Enzyme based acceleration of absorption of hydrophobic drugs: an in vitro study. Molecular Pharmaceutics. 10: 3519-24. PMID 23937162 DOI: 10.1021/Mp400272M  0.36
2013 Kim A, Mujumdar S, Siegel R. Swelling Properties of Hydrogels Containing Phenylboronic Acids Chemosensors. 2: 1-12. DOI: 10.3390/chemosensors2010001  0.762
2012 Koonar I, Zhou C, Hillmyer MA, Lodge TP, Siegel RA. ABC triblock terpolymers exhibiting both temperature- and pH-sensitive micellar aggregation and gelation in aqueous solution. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 17785-94. PMID 23189918 DOI: 10.1021/La303712B  0.708
2012 Feldstein MM, Siegel RA. Molecular and nanoscale factors governing pressure-sensitive adhesion strength of viscoelastic polymers Journal of Polymer Science, Part B: Polymer Physics. 50: 739-772. DOI: 10.1002/Polb.23065  0.311
2011 Feldstein MM, Bermesheva EV, Jean YC, Misra GP, Siegel RA. Free volume, adhesion, and viscoelastic properties of model nanostructured pressure-sensitive adhesive based on stoichiometric complex of poly(N-vinyl pyrrolidone) and poly(ethylene glycol) of disparate chain lengths Journal of Applied Polymer Science. 119: 2408-2421. DOI: 10.1002/App.32917  0.32
2010 Vermonden T, Jena SS, Barriet D, Censi R, van der Gucht J, Hennink WE, Siegel RA. Macromolecular Diffusion in Self-Assembling Biodegradable Thermosensitive Hydrogels. Macromolecules. 43: 782-789. PMID 20885989 DOI: 10.1021/Ma902186E  0.392
2010 Xu F, Liu G, Zhang Q, Siegel RA. A comparative study on two phenylboronic acid based glucose-sensitive hydrogels. Frontiers in Bioscience (Elite Edition). 2: 657-67. PMID 20036909 DOI: 10.2741/E121  0.379
2010 Siegel RA, Gu Y, Lei M, Baldi A, Nuxoll EE, Ziaie B. Hard and soft micro- and nanofabrication: An integrated approach to hydrogel-based biosensing and drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 141: 303-13. PMID 20036310 DOI: 10.1016/J.Jconrel.2009.12.012  0.608
2009 Nuxoll EE, Hillmyer MA, Wang R, Leighton C, Siegel RA. Composite block polymer-microfabricated silicon nanoporous membrane. Acs Applied Materials & Interfaces. 1: 888-93. PMID 20160882 DOI: 10.1021/Am900013V  0.335
2009 Nuxoll EE, Siegel RA. BioMEMS devices for drug delivery. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 28: 31-9. PMID 19150769 DOI: 10.1109/Memb.2008.931014  0.308
2009 Lei M, Baldi A, Nuxoll E, Siegel RA, Ziaie B. Hydrogel-based microsensors for wireless chemical monitoring. Biomedical Microdevices. 11: 529-38. PMID 18335316 DOI: 10.1007/S10544-008-9168-5  0.36
2009 Gaumet M, Xi J, Barriet D, Siegel RA. Stimuli-Responsive Triblock Polymers for Multipulse Drug Delivery Journal of Medical Devices. 3. DOI: 10.1115/1.3155366  0.448
2009 Barriet D, Siegel RA. Microfabrication of a Device to Evaluate the Swelling of Glucose Sensitive Hydrogels Under Isochoric Conditions Journal of Medical Devices. 3. DOI: 10.1115/1.3136753  0.342
2009 Gu Y, Dhanarajan AP, Hruby SL, Baldi A, Ziaie B, Siegel RA. An interpenetrating glass-thermosensitive hydrogel construct. Gated flow control and thermofluidic oscillations Sensors and Actuators, B: Chemical. 138: 631-636. DOI: 10.1016/J.Snb.2009.02.044  0.75
2008 Mujumdar SK, Siegel RA. Introduction of pH-Sensitivity into Mechanically Strong Nanoclay Composite Hydrogels Based on N-Isopropylacrylamide. Journal of Polymer Science. Part a, Polymer Chemistry. 46: 6630-6640. PMID 19802380 DOI: 10.1002/Pola.22973  0.787
2008 Nuxoll EE, Hillmyer MA, Siegel RA. Development of Nanoporous Ultrathin Membranes For Implantable Drug Delivery Journal of Medical Devices. 2. DOI: 10.1115/1.2927432  0.335
2008 Varigonda S, Georgiou TT, Siegel RA, Daoutidis P. Optimal periodic control of a drug delivery system Computers and Chemical Engineering. 32: 2256-2262. DOI: 10.1016/S1474-6670(17)31937-7  0.317
2008 Bayramov DF, Singh P, Cleary GW, Siegel RA, Chalykh AE, Feldstein MM. Non-covalently crosslinked hydrogels displaying a unique combination of water-absorbing, elastic and adhesive properties Polymer International. 57: 785-790. DOI: 10.1002/Pi.2417  0.393
2008 Bhalla AS, Mujumdar S, Siegel RA. Factors governing glucose-driven pH oscillations in a hydrogel-enzyme- marble reactor American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 49: 769-770.  0.556
2007 Lei M, Ziaie B, Nuxoll E, Iván K, Noszticzius Z, Siegel RA. Integration of hydrogels with hard and soft microstructures. Journal of Nanoscience and Nanotechnology. 7: 780-9. PMID 17450833 DOI: 10.1166/Jnn.2007.513  0.378
2007 Siegel RA. Investigation of a cellular pharmacodynamic model exhibiting sharp response sensitivity and tolerance. Journal of Pharmacokinetics and Pharmacodynamics. 34: 87-101. PMID 17160695 DOI: 10.1007/S10928-006-9042-0  0.319
2007 Mujumdar SK, Bhalla AS, Siegel RA. Novel hydrogels for rhythmic pulsatile drug delivery Macromolecular Symposia. 254: 338-344. DOI: 10.1002/Masy.200750849  0.779
2006 Hou H, Siegel RA. Enhanced permeation of diazepam through artificial membranes from supersaturated solutions. Journal of Pharmaceutical Sciences. 95: 896-905. PMID 16493587 DOI: 10.1002/Jps.20600  0.569
2006 Lei M, Baldi A, Nuxoll E, Siegel RA, Ziaie B. A hydrogel-based implantable micromachined transponder for wireless glucose measurement. Diabetes Technology & Therapeutics. 8: 112-22. PMID 16472058 DOI: 10.1089/Dia.2006.8.112  0.357
2006 Baldi A, Lei M, Gu Y, Siegel RA, Ziaie B. A microstructured silicon membrane with entrapped hydrogels for environmentally sensitive fluid gating Sensors and Actuators, B: Chemical. 114: 9-18. DOI: 10.1016/J.Snb.2005.04.020  0.627
2004 Ziaie B, Siegel RA. Hydrogel-Based BioMEMS platforms for smart drug delivery. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 4: 2670. PMID 17511110  0.337
2004 Lei M, Salim A, Siegel R, Ziaie B. A hydrogel-actuated microvalve for smart flow control. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 3: 2041-4. PMID 17272120 DOI: 10.1109/IEMBS.2004.1403600  0.323
2004 Lei M, Gu Y, Baldi A, Siegel R, Ziaie B. Soft mold-dry etch: a novel hydrogel patterning technique for biomedical applications. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 3: 1983-6. PMID 17272105 DOI: 10.1109/IEMBS.2004.1403585  0.548
2004 Lei M, Gu Y, Baldi A, Siegel RA, Ziaie B. High-resolution technique for fabricating environmentally sensitive hydrogel microstructures. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 8947-51. PMID 15461469 DOI: 10.1021/La048719Y  0.592
2004 Ziaie B, Baldi A, Lei M, Gu Y, Siegel RA. Hard and soft micromachining for BioMEMS: review of techniques and examples of applications in microfluidics and drug delivery. Advanced Drug Delivery Reviews. 56: 145-72. PMID 14741113 DOI: 10.1016/J.Addr.2003.09.001  0.583
2004 Siegel RA, Gu Y, Baldi A, Ziaie B. Novel swelling/shrinking behaviors of glucose-binding hydrogels and their potential use in a microfluidic insulin delivery system Macromolecular Symposia. 207: 249-256. DOI: 10.1002/Masy.200450322  0.617
2004 Dhanarajan AP, Urban J, Siegel RA. A model for a hydrogel-enzyme chemomechanical oscillator Acs Symposium Series. 869: 44-57.  0.759
2003 Baldi A, Gu Y, Loftness PE, Siegel RA, Ziaie B. A hydrogel-actuated environmentally sensitive microvalve for active flow control Journal of Microelectromechanical Systems. 12: 613-621. DOI: 10.1109/Jmems.2003.818070  0.621
2003 Baldi A, Lei M, Gu Y, Siegel RA, Ziaie B. An environmentally responsive microflow controller with double side tethered structure for the entrapment of hydrogel Proceedings of the Ieee Micro Electro Mechanical Systems (Mems). 84-87.  0.544
2002 Misra GP, Siegel RA. Ionizable drugs and pH oscillators: buffering effects. Journal of Pharmaceutical Sciences. 91: 2003-15. PMID 12210047 DOI: 10.1002/Jps.10189  0.417
2002 Misra GP, Siegel RA. New mode of drug delivery: long term autonomous rhythmic hormone release across a hydrogel membrane. Journal of Controlled Release : Official Journal of the Controlled Release Society. 81: 1-6. PMID 11992673 DOI: 10.1016/S0168-3659(02)00043-3  0.366
2002 Misra GP, Siegel RA. Multipulse drug permeation across a membrane driven by a chemical pH-oscillator. Journal of Controlled Release : Official Journal of the Controlled Release Society. 79: 293-7. PMID 11853939 DOI: 10.1016/S0168-3659(01)00523-5  0.404
2002 Gu Y, Baldi A, Ziaie B, Siegel RA. Modulation of drug delivery rate by hydrogel-incorporating MEMS devices 2nd Annual International Ieee-Embs Special Topic Conference On Microtechnologies in Medicine and Biology - Proceedings. 406-409. DOI: 10.1109/MMB.2002.1002356  0.587
2002 Dhanarajan AP, Misra GP, Siegel RA. Autonomous chemomechanical oscillations in a hydrogel/enzyme system driven by glucose Journal of Physical Chemistry A. 106: 8835-8838. DOI: 10.1021/Jp026086V  0.77
2002 Bairamov DF, Chalykh AE, Feldstein MM, Siegel RA. Impact of molecular weight on miscibility and interdiffusion between poly(N-vinyl pyrrolidone) and poly(ethylene glycol) Macromolecular Chemistry and Physics. 203: 2674-2685. DOI: 10.1002/Macp.200290050  0.302
2002 Bairamov DF, Chalykh AE, Feldstein MM, Siegel RA, Plate NA. Dissolution and mutual diffusion of poly(N-vinyl pyrrolidone) in short-chain poly(ethylene glycol) as observed by optical wedge microinterferometry Journal of Applied Polymer Science. 85: 1128-1136. DOI: 10.1002/App.10635  0.335
2000 Li B, Siegel RA. Global analysis of a model pulsing drug delivery oscillator based on chemomechanical feedback with hysteresis. Chaos (Woodbury, N.Y.). 10: 682-690. PMID 12779418 DOI: 10.1063/1.1286998  0.325
2000 Siegel RA. Theoretical analysis of inward hemispheric release above and below drug solubility Journal of Controlled Release. 69: 109-126. PMID 11018550 DOI: 10.1016/S0168-3659(00)00292-3  0.332
1999 Leroux JC, Siegel RA. Autonomous gel/enzyme oscillator fueled by glucose: Preliminary evidence for oscillations. Chaos (Woodbury, N.Y.). 9: 267-275. PMID 12779824 DOI: 10.1063/1.166403  0.377
1998 Siegel RA. A lesson from secretory granules Nature. 394: 427-428. PMID 9697762 DOI: 10.1038/28756  0.303
1997 Zou X, Leroux JC, Baker JP, Siegel RA. pH-hysteresis of glucose permeability in acid-doped LCST hydrogels - a basis for pulsatile, oscillatory drug release Polymeric Materials Science and Engineering, Proceedings of the Acs Division of Polymeric Materials Science and Engineering. 76: 444-445.  0.321
1996 Baker JP, Siegel RA. Hysteresis in the glucose permeability versus pH characteristic for a responsive hydrogel membrane Macromolecular Rapid Communications. 17: 409-415. DOI: 10.1002/Marc.1996.030170607  0.427
1995 Cornejo-Bravo JM, Arias-Sanchez V, Alvarez-Anguiano A, Siegel RA. Kinetics of drug release from hydrophobic polybasic gels: effect of buffer acidity Journal of Controlled Release. 33: 223-229. DOI: 10.1016/0168-3659(94)00086-A  0.436
1995 Siegel RA, Pitt CG. A strategy for oscillatory drug release general scheme and simplified theory Journal of Controlled Release. 33: 173-188. DOI: 10.1016/0168-3659(94)00082-6  0.345
1994 Firestone BA, Siegel RA. pH, salt, and buffer dependent swelling in ionizable copolymer gels: Tests of the ideal Donnan equilibrium theory Journal of Biomaterials Science, Polymer Edition. 5: 433-450. PMID 8038138 DOI: 10.1163/156856294X00130  0.361
1993 Siegel RA. Hydrophobic weak polyelectrolyte gels: Studies of swelling equilibria and kinetics Advances in Polymer Science. 109: 233-267. DOI: 10.1007/3-540-56791-7_6  0.39
1992 Siegel RA, Johannes I, Hunt CA, Firestone BA. Buffer Effects on Swelling Kinetics in Polybasic Gels Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 76-81. PMID 1589413 DOI: 10.1023/A:1018983828027  0.438
1992 Sassi AP, Beltrán S, Hooper HH, Blanch HW, Prausnitz J, Siegel RA. Monte Carlo simulations of hydrophobic weak polyelectrolytes: Titration properties and pH-induced structural transitions for polymers containing weak electrolytes The Journal of Chemical Physics. 97: 8767-8774. DOI: 10.1063/1.463346  0.333
1992 Chou LY, Blanch HW, Prausnitz JM, Siegel RA. Buffer effects on aqueous swelling kinetics of polyelectrolyte gels Journal of Applied Polymer Science. 45: 1411-1423. DOI: 10.1002/App.1992.070450810  0.408
1991 Pamela De Moor C, Doh L, Siegel RA. Long-term structural changes in pH-sensitive hydrogels Biomaterials. 12: 836-840. PMID 1764554 DOI: 10.1016/0142-9612(91)90071-H  0.378
1991 Firestone BA, Siegel RA. Kinetics and mechanisms of water sorption in hydrophobic, ionizable copolymer gels Journal of Applied Polymer Science. 43: 901-914. DOI: 10.1002/App.1991.070430507  0.408
1990 Siegel RA, Langer R. Mechanistic studies of macromolecular drug release from macroporous polymers. II. Models for the slow kinetics of drug release Journal of Controlled Release. 14: 153-167. DOI: 10.1016/0168-3659(90)90152-J  0.462
1990 Siegel RA, Firestone BA. Mechanochemical approaches to self-regulating insulin pump design Journal of Controlled Release. 11: 181-192. DOI: 10.1016/0168-3659(90)90131-C  0.332
1990 Siegel RA, Firestone BA, Johannes I, Cornejo J. Weak ionic hydrogels. Effects of pH, ionic strength, and buffer composition on swelling equilibria, kinetics, and solute release American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 31: 231-232.  0.332
1989 Siegel RA, Kost J, Langer R. Mechanistic studies of macromolecular drug release from macroporous polymers. I. Experiments and preliminary theory concerning completeness of drug release Journal of Controlled Release. 8: 223-236. DOI: 10.1016/0168-3659(89)90044-8  0.44
1988 Siegel RA, Firestone BA. pH-dependent equilibrium swelling properties of hydrophobic polyelectrolyte copolymer gels Macromolecules. 21: 3254-3259. DOI: 10.1021/Ma00189A021  0.308
1988 Siegel RA, Falamarzian M, Firestone BA, Moxley BC. pH-Controlled release from hydrophobic/polyelectrolyte copolymer hydrogels Journal of Controlled Release. 8: 179-182. DOI: 10.1016/0168-3659(88)90044-2  0.397
1985 Balazs AC, Calef DF, Deutch JM, Siegel RA, Langer R. The role of polymer matrix structure and interparticle interactions in diffusion-limited drug release. Biophysical Journal. 47: 97-104. PMID 3978194 DOI: 10.1016/S0006-3495(85)83881-9  0.407
1985 Langer R, Siegel R, Brown L, Leong K, Kost J, Edelman E. Controlled release and magnetically modulated systems for macromolecular drugs. Annals of the New York Academy of Sciences. 446: 1-13. PMID 3893280 DOI: 10.1111/J.1749-6632.1985.Tb18386.X  0.612
1984 Cohen J, Siegel RA, Langer R. Sintering technique for the preparation of polymer matrices for the controlled release of macromolecules Journal of Pharmaceutical Sciences. 73: 1034-1037. PMID 6491905 DOI: 10.1002/Jps.2600730805  0.462
1984 Siegel RA, Langer R. Controlled Release of Polypeptides and Other Macromolecules Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 1: 2-10. DOI: 10.1023/A:1016318423563  0.455
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