Rudolf Jaenisch - Publications

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Mouse development
Website:
http://www.wi.mit.edu/research/faculty/jaenisch.html

359 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ma H, de Zwaan E, Guo YE, Cejas P, Thiru P, van de Bunt M, Jeppesen JF, Syamala S, Dall'Agnese A, Abraham BJ, Fu D, Garrett-Engele C, Lee TI, Long HW, Griffith LG, ... ... Jaenisch R, et al. The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes. Cell Stem Cell. PMID 35452598 DOI: 10.1016/j.stem.2022.03.015  0.438
2021 Zhang L, Richards A, Barrasa MI, Hughes SH, Young RA, Jaenisch R. Reply to Briggs et al.: Genomic integration and expression of SARS-CoV-2 sequences can explain prolonged or recurrent viral RNA detection. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34702742 DOI: 10.1073/pnas.2114995118  0.343
2021 Zhang L, Richards A, Barrasa MI, Hughes SH, Young RA, Jaenisch R. Response to Parry et al.: Strong evidence for genomic integration of SARS-CoV-2 sequences and expression in patient tissues. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34344760 DOI: 10.1073/pnas.2109497118  0.344
2021 Zhang L, Richards A, Barrasa MI, Hughes SH, Young RA, Jaenisch R. Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33958444 DOI: 10.1073/pnas.2105968118  0.41
2021 Trapecar M, Wogram E, Svoboda D, Communal C, Omer A, Lungjangwa T, Sphabmixay P, Velazquez J, Schneider K, Wright CW, Mildrum S, Hendricks A, Levine S, Muffat J, Lee MJ, ... ... Jaenisch R, et al. Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases. Science Advances. 7. PMID 33514545 DOI: 10.1126/sciadv.abd1707  0.705
2020 Zhang L, Richards A, Khalil A, Wogram E, Ma H, Young RA, Jaenisch R. SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome. Biorxiv : the Preprint Server For Biology. PMID 33330870 DOI: 10.1101/2020.12.12.422516  0.411
2020 Li CH, Coffey EL, Dall'Agnese A, Hannett NM, Tang X, Henninger JE, Platt JM, Oksuz O, Zamudio AV, Afeyan LK, Schuijers J, Liu XS, Markoulaki S, Lungjangwa T, LeRoy G, ... ... Jaenisch R, et al. MeCP2 links heterochromatin condensates and neurodevelopmental disease. Nature. PMID 32698189 DOI: 10.1038/S41586-020-2574-4  0.624
2020 Huang Q, Cohen MA, Alsina FC, Devlin G, Garrett A, McKey J, Havlik P, Rakhilin N, Wang E, Xiang K, Mathews P, Wang L, Bock C, Ruthig V, Wang Y, ... ... Jaenisch R, et al. Intravital imaging of mouse embryos. Science (New York, N.Y.). 368: 181-186. PMID 32273467 DOI: 10.1126/Science.Aba0210  0.621
2020 Cohen MA, Zhang S, Sengupta S, Ma H, Bell GW, Horton B, Sharma B, George RE, Spranger S, Jaenisch R. Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras. Cell Stem Cell. PMID 32142683 DOI: 10.1016/J.Stem.2020.02.001  0.325
2020 Dees C, Pötter S, Zhang Y, Bergmann C, Zhou X, Luber M, Wohlfahrt T, Karouzakis E, Ramming A, Gelse K, Yoshimura A, Jaenisch R, Distler O, Schett G, Distler JH. TGFβ-induced epigenetic deregulation of SOCS3 facilitates STAT3-signaling to promote fibrosis. The Journal of Clinical Investigation. PMID 31990678 DOI: 10.1172/Jci122462  0.342
2019 Svoboda DS, Barrasa MI, Shu J, Rietjens R, Zhang S, Mitalipova M, Berube P, Fu D, Shultz LD, Bell GW, Jaenisch R. Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31772018 DOI: 10.1073/Pnas.1913541116  0.397
2019 Liu XS, Jaenisch R. Editing the Epigenome to Tackle Brain Disorders. Trends in Neurosciences. PMID 31706628 DOI: 10.1016/J.Tins.2019.10.003  0.521
2019 Song Y, van den Berg PR, Markoulaki S, Soldner F, Dall'Agnese A, Henninger JE, Drotar J, Rosenau N, Cohen MA, Young RA, Semrau S, Stelzer Y, Jaenisch R. Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs. Molecular Cell. PMID 31422875 DOI: 10.1016/J.Molcel.2019.06.045  0.533
2019 Tang X, Drotar J, Li K, Clairmont CD, Brumm AS, Sullins AJ, Wu H, Liu XS, Wang J, Gray NS, Sur M, Jaenisch R. Pharmacological enhancement of gene expression exerts therapeutic effects on human Rett syndrome neurons and mutant mice. Science Translational Medicine. 11. PMID 31366578 DOI: 10.1126/Scitranslmed.Aau0164  0.339
2019 Tian TV, Di Stefano B, Stik G, Vila-Casadesús M, Sardina JL, Vidal E, Dasti A, Segura-Morales C, De Andrés-Aguayo L, Gómez A, Goldmann J, Jaenisch R, Graf T. Whsc1 links pluripotency exit with mesendoderm specification. Nature Cell Biology. PMID 31235934 DOI: 10.1038/S41556-019-0342-1  0.433
2019 Li Y, Muffat J, Omer Javed A, Keys HR, Lungjangwa T, Bosch I, Khan M, Virgilio MC, Gehrke L, Sabatini DM, Jaenisch R. Genome-wide CRISPR screen for Zika virus resistance in human neural cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019072 DOI: 10.1073/Pnas.1900867116  0.762
2019 Schiebinger G, Shu J, Tabaka M, Cleary B, Subramanian V, Solomon A, Gould J, Liu S, Lin S, Berube P, Lee L, Chen J, Brumbaugh J, Rigollet P, Hochedlinger K, ... Jaenisch R, et al. Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming. Cell. PMID 30712874 DOI: 10.1016/J.Cell.2019.01.006  0.377
2018 Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, ... ... Jaenisch R, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Molecular Cell. PMID 30527540 DOI: 10.1016/J.Molcel.2018.11.028  0.78
2018 Omer Javed A, Li Y, Muffat J, Su KC, Cohen MA, Lungjangwa T, Aubourg P, Cheeseman IM, Jaenisch R. Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Reports. 25: 368-382.e5. PMID 30304678 DOI: 10.1016/J.Celrep.2018.09.032  0.75
2018 Jacobsen JT, Mesin L, Markoulaki S, Schiepers A, Cavazzoni CB, Bousbaine D, Jaenisch R, Victora GD. One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation. The Journal of Experimental Medicine. PMID 30181412 DOI: 10.1084/Jem.20172064  0.332
2018 Muffat J, Li Y, Omer A, Durbin A, Bosch I, Bakiasi G, Richards E, Meyer A, Gehrke L, Jaenisch R. Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915057 DOI: 10.1073/Pnas.1719266115  0.76
2018 Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R. Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas. Proceedings of the National Academy of Sciences of the United States of America. PMID 29599125 DOI: 10.1073/Pnas.1702059115  0.376
2018 Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, et al. Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors. Molecular Psychiatry. 23: 791. PMID 29565043 DOI: 10.1038/Mp.2018.5  0.391
2018 Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R. Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell. PMID 29456084 DOI: 10.1016/J.Cell.2018.01.012  0.802
2018 Zabala M, Lobo NA, Seoane JA, Stelzer Y, Luong AV, Isobe T, Zarnegar MA, Watanabe N, Antoñana S, Lam J, Qian D, Sikandar SS, Kuo AH, Heitink LS, Shimono Y, ... ... Jaenisch R, et al. Abstract B67: The DLK1-DIO3 imprinted region regulates long-term proliferation in normal and malignant breast epithelium Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-B67  0.32
2017 Weintraub AS, Li CH, Zamudio AV, Sigova AA, Hannett NM, Day DS, Abraham BJ, Cohen MA, Nabet B, Buckley DL, Guo YE, Hnisz D, Jaenisch R, Bradner JE, Gray NS, et al. YY1 Is a Structural Regulator of Enhancer-Promoter Loops. Cell. 171: 1573-1588.e28. PMID 29224777 DOI: 10.1016/J.Cell.2017.11.008  0.487
2017 Pei D, Beier DW, Levy-Lahad E, Marchant G, Rossant J, Izpisua Belmonte JC, Lovell-Badge R, Jaenisch R, Charo A, Baltimore D. Human Embryo Editing: Opportunities and Importance of Transnational Cooperation. Cell Stem Cell. 21: 423-426. PMID 28985523 DOI: 10.1016/J.Stem.2017.09.010  0.463
2017 Harikumar A, Edupuganti RR, Sorek M, Azad GK, Markoulaki S, Sehnalová P, Legartová S, Bártová E, Farkash-Amar S, Jaenisch R, Alon U, Meshorer E. An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells. Stem Cell Reports. PMID 28966122 DOI: 10.1016/J.Stemcr.2017.08.022  0.337
2017 Edupuganti RR, Harikumar A, Aaronson Y, Biran A, Sailaja BS, Nissim-Rafinia M, Azad GK, Cohen MA, Park JE, Shivalila CS, Markoulaki S, Sze SK, Jaenisch R, Meshorer E. Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation. Stem Cell Reports. PMID 28966118 DOI: 10.1016/J.Stemcr.2017.08.021  0.423
2017 Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, et al. MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling. Molecular Psychiatry. PMID 28439102 DOI: 10.1038/Mp.2017.86  0.406
2017 Feng J, Pena CJ, Purushothaman I, Engmann O, Walker D, Brown AN, Issler O, Doyle M, Harrigan E, Mouzon E, Vialou V, Shen L, Dawlaty MM, Jaenisch R, Nestler EJ. Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28074830 DOI: 10.1038/Npp.2017.6  0.446
2016 Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R. Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. PMID 28041895 DOI: 10.1016/J.Stem.2016.11.017  0.748
2016 Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K. Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation. Cell Stem Cell. PMID 27989770 DOI: 10.1016/J.Stem.2016.10.006  0.742
2016 Wu J, Greely HT, Jaenisch R, Nakauchi H, Rossant J, Belmonte JC. Stem cells and interspecies chimaeras. Nature. 540: 51-59. PMID 27905428 DOI: 10.1038/Nature20573  0.369
2016 Banerjee A, Rikhye RV, Breton-Provencher V, Tang X, Li C, Li K, Runyan CA, Fu Z, Jaenisch R, Sur M. Jointly reduced inhibition and excitation underlies circuit-wide changes in cortical processing in Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 27803317 DOI: 10.1073/Pnas.1615330113  0.32
2016 Muffat J, Li Y, Jaenisch R. CNS disease models with human pluripotent stem cells in the CRISPR age. Current Opinion in Cell Biology. 43: 96-103. PMID 27768957 DOI: 10.1016/J.Ceb.2016.10.001  0.77
2016 Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, Bakiasi G, Tsai LH, Aubourg P, Ransohoff RM, Jaenisch R. Efficient derivation of microglia-like cells from human pluripotent stem cells. Nature Medicine. PMID 27668937 DOI: 10.1038/Nm.4189  0.785
2016 Liu XS, Wu H, Ji X, Stelzer Y, Wu X, Czauderna S, Shu J, Dadon D, Young RA, Jaenisch R. Editing DNA Methylation in the Mammalian Genome. Cell. 167: 233-247.e17. PMID 27662091 DOI: 10.1016/J.Cell.2016.08.056  0.65
2016 Stelzer Y, Wu H, Song Y, Shivalila CS, Markoulaki S, Jaenisch R. Parent-of-Origin DNA Methylation Dynamics during Mouse Development. Cell Reports. 16: 3167-80. PMID 27653683 DOI: 10.1016/J.Celrep.2016.08.066  0.391
2016 Theunissen TW, Friedli M, He Y, Planet E, O'Neil RC, Markoulaki S, Pontis J, Wang H, Iouranova A, Imbeault M, Duc J, Cohen MA, Wert KJ, Castanon R, Zhang Z, ... ... Jaenisch R, et al. Molecular Criteria for Defining the Naive Human Pluripotent State. Cell Stem Cell. PMID 27424783 DOI: 10.1016/J.Stem.2016.06.011  0.41
2016 Hockemeyer D, Jaenisch R. Induced Pluripotent Stem Cells Meet Genome Editing. Cell Stem Cell. 18: 573-86. PMID 27152442 DOI: 10.1016/J.Stem.2016.04.013  0.697
2016 Soldner F, Stelzer Y, Shivalila CS, Abraham BJ, Latourelle JC, Barrasa MI, Goldmann J, Myers RH, Young RA, Jaenisch R. Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression. Nature. PMID 27096366 DOI: 10.1038/Nature17939  0.522
2016 Hnisz D, Weintraub AS, Day DS, Valton AL, Bak RO, Li CH, Goldmann J, Lajoie BR, Fan ZP, Sigova AA, Reddy J, Borges-Rivera D, Lee TI, Jaenisch R, Porteus MH, et al. Activation of proto-oncogenes by disruption of chromosome neighborhoods. Science (New York, N.Y.). PMID 26940867 DOI: 10.1126/Science.Aad9024  0.505
2016 Cohen MA, Wert KJ, Goldmann J, Markoulaki S, Buganim Y, Fu D, Jaenisch R. Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos. Proceedings of the National Academy of Sciences of the United States of America. PMID 26811475 DOI: 10.1073/Pnas.1525518113  0.415
2016 Carroll B, Maetzel D, Maddocks OD, Otten G, Ratcliff M, Smith GR, Dunlop EA, Passos JF, Davies OR, Jaenisch R, Tee AR, Sarkar S, Korolchuk VI. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. Elife. 5. PMID 26742086 DOI: 10.7554/Elife.11058  0.316
2015 Ji X, Dadon DB, Powell BE, Fan ZP, Borges-Rivera D, Shachar S, Weintraub AS, Hnisz D, Pegoraro G, Lee TI, Misteli T, Jaenisch R, Young RA. 3D Chromosome Regulatory Landscape of Human Pluripotent Cells. Cell Stem Cell. PMID 26686465 DOI: 10.1016/J.Stem.2015.11.007  0.559
2015 De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Corrigendum: Hallmarks of pluripotency. Nature. PMID 26675727 DOI: 10.1038/Nature16470  0.635
2015 De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Jaenisch R, et al. Corrigendum: Failure to replicate the STAP cell phenomenon. Nature. PMID 26675720 DOI: 10.1038/Nature16479  0.596
2015 Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, ... ... Jaenisch R, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/J.Stemcr.2015.10.011  0.547
2015 D'Alessio AC, Fan ZP, Wert KJ, Baranov P, Cohen MA, Saini JS, Cohick E, Charniga C, Dadon D, Hannett NM, Young MJ, Temple S, Jaenisch R, Lee TI, Young RA. A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity. Stem Cell Reports. PMID 26603904 DOI: 10.1016/J.Stemcr.2015.09.016  0.562
2015 De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Jaenisch R, et al. Failure to replicate the STAP cell phenomenon. Nature. 525: E6-9. PMID 26399835 DOI: 10.1038/Nature15513  0.596
2015 De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Hallmarks of pluripotency. Nature. 525: 469-78. PMID 26399828 DOI: 10.1038/Nature15515  0.663
2015 Cimmino L, Dawlaty MM, Ndiaye-Lobry D, Yap YS, Bakogianni S, Yu Y, Bhattacharyya S, Shaknovich R, Geng H, Lobry C, Mullenders J, King B, Trimarchi T, Aranda-Orgilles B, Liu C, ... ... Jaenisch R, et al. TET1 is a tumor suppressor of hematopoietic malignancy. Nature Immunology. 16: 653-62. PMID 25867473 DOI: 10.1038/Ni.3148  0.404
2015 Ji X, Dadon DB, Abraham BJ, Lee TI, Jaenisch R, Bradner JE, Young RA. Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions. Proceedings of the National Academy of Sciences of the United States of America. 112: 3841-6. PMID 25755260 DOI: 10.1073/Pnas.1502971112  0.487
2015 Deuse T, Wang D, Stubbendorff M, Itagaki R, Grabosch A, Greaves LC, Alawi M, Grünewald A, Hu X, Hua X, Velden J, Reichenspurner H, Robbins RC, Jaenisch R, Weissman IL, et al. SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts. Cell Stem Cell. 16: 33-8. PMID 25465116 DOI: 10.1016/J.Stem.2014.11.003  0.35
2015 Dougan SK, Bilate A, Jaenisch R, Ploegh HL. Abstract B59: Transnuclear mice as models of the immune response to pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B59  0.315
2014 Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, ... ... Jaenisch R, et al. Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency. Cell Stem Cell. 15: 524-526. PMID 28903030 DOI: 10.1016/j.stem.2014.09.003  0.383
2014 Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, ... ... Jaenisch R, et al. Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency. Cell Stem Cell. 15: 523. PMID 28903029 DOI: 10.1016/J.Stem.2014.08.002  0.46
2014 Cassady JP, D'Alessio AC, Sarkar S, Dani VS, Fan ZP, Ganz K, Roessler R, Sur M, Young RA, Jaenisch R. Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cells. Stem Cell Reports. 3: 948-56. PMID 25454632 DOI: 10.1016/J.Stemcr.2014.10.001  0.583
2014 Flierl A, Oliveira LM, Falomir-Lockhart LJ, Mak SK, Hesley J, Soldner F, Arndt-Jovin DJ, Jaenisch R, Langston JW, Jovin TM, Schüle B. Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication. Plos One. 9: e112413. PMID 25390032 DOI: 10.1371/Journal.Pone.0112413  0.394
2014 Katz Y, Li F, Lambert NJ, Sokol ES, Tam WL, Cheng AW, Airoldi EM, Lengner CJ, Gupta PB, Yu Z, Jaenisch R, Burge CB. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. Elife. 3: e03915. PMID 25380226 DOI: 10.7554/Elife.03915  0.318
2014 Buganim Y, Markoulaki S, van Wietmarschen N, Hoke H, Wu T, Ganz K, Akhtar-Zaidi B, He Y, Abraham BJ, Porubsky D, Kulenkampff E, Faddah DA, Shi L, Gao Q, Sarkar S, ... ... Jaenisch R, et al. The developmental potential of iPSCs is greatly influenced by reprogramming factor selection. Cell Stem Cell. 15: 295-309. PMID 25192464 DOI: 10.1016/J.Stem.2014.07.003  0.553
2014 Sexton AN, Regalado SG, Lai CS, Cost GJ, O'Neil CM, Urnov FD, Gregory PD, Jaenisch R, Collins K, Hockemeyer D. Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation. Genes & Development. 28: 1885-99. PMID 25128433 DOI: 10.1101/Gad.246819.114  0.719
2014 Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, ... ... Jaenisch R, et al. Systematic identification of culture conditions for induction and maintenance of naive human pluripotency. Cell Stem Cell. 15: 471-87. PMID 25090446 DOI: 10.1016/J.Stem.2014.07.002  0.482
2014 Maetzel D, Sarkar S, Wang H, Abi-Mosleh L, Xu P, Cheng AW, Gao Q, Mitalipova M, Jaenisch R. Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells. Stem Cell Reports. 2: 866-80. PMID 24936472 DOI: 10.1016/J.Stemcr.2014.03.014  0.361
2014 Forster R, Chiba K, Schaeffer L, Regalado SG, Lai CS, Gao Q, Kiani S, Farin HF, Clevers H, Cost GJ, Chan A, Rebar EJ, Urnov FD, Gregory PD, Pachter L, ... Jaenisch R, et al. Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells. Stem Cell Reports. 2: 838-52. PMID 24936470 DOI: 10.1016/J.Stemcr.2014.05.001  0.711
2014 Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6. PMID 24752079 DOI: 10.1038/Nbt.2889  0.502
2014 Dawlaty MM, Breiling A, Le T, Barrasa MI, Raddatz G, Gao Q, Powell BE, Cheng AW, Faull KF, Lyko F, Jaenisch R. Loss of Tet enzymes compromises proper differentiation of embryonic stem cells. Developmental Cell. 29: 102-11. PMID 24735881 DOI: 10.1016/J.Devcel.2014.03.003  0.577
2014 Armond JW, Saha K, Rana AA, Oates CJ, Jaenisch R, Nicodemi M, Mukherjee S. A stochastic model dissects cell states in biological transition processes. Scientific Reports. 4: 3692. PMID 24435049 DOI: 10.1038/Srep03692  0.356
2014 Katz Y, Li F, Lambert NJ, Sokol ES, Tam W, Cheng AW, Airoldi EM, Lengner CJ, Gupta PB, Yu Z, Jaenisch R, Burge CB. Author response: Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state Elife. DOI: 10.7554/Elife.03915.025  0.326
2014 Forster R, Chiba K, Schaeffer L, Regalado S, Lai C, Gao Q, Kiani S, Farin H, Clevers H, Cost G, Chan A, Rebar E, Urnov F, Gregory P, Pachter L, ... Jaenisch R, et al. Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells Stem Cell Reports. 3: 215. DOI: 10.1016/J.Stemcr.2014.06.014  0.703
2014 Theunissen T, Powell B, Wang H, Mitalipova M, Faddah D, Reddy J, Fan Z, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, ... ... Jaenisch R, et al. Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency (DOI:10.1016/j.stem.2014.07.002) Cell Stem Cell. DOI: 10.1016/j.stem.2014.08.002  0.427
2013 Dougan SK, Dougan M, Kim J, Turner JA, Ogata S, Cho HI, Jaenisch R, Celis E, Ploegh HL. Transnuclear TRP1-specific CD8 T cells with high or low affinity TCRs show equivalent antitumor activity. Cancer Immunology Research. 1: 99-111. PMID 24459675 DOI: 10.1158/2326-6066.Cir-13-0047  0.332
2013 Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, ... ... Jaenisch R, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/Science.1245296  0.791
2013 Li Y, Wang H, Muffat J, Cheng AW, Orlando DA, Lovén J, Kwok SM, Feldman DA, Bateup HS, Gao Q, Hockemeyer D, Mitalipova M, Lewis CA, Vander Heiden MG, Sur M, ... ... Jaenisch R, et al. Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. Cell Stem Cell. 13: 446-58. PMID 24094325 DOI: 10.1016/J.Stem.2013.09.001  0.806
2013 Rudenko A, Dawlaty MM, Seo J, Cheng AW, Meng J, Le T, Faull KF, Jaenisch R, Tsai LH. Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron. 79: 1109-22. PMID 24050401 DOI: 10.1016/J.Neuron.2013.08.003  0.571
2013 Yang H, Wang H, Shivalila CS, Cheng AW, Shi L, Jaenisch R. One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell. 154: 1370-9. PMID 23992847 DOI: 10.1016/J.Cell.2013.08.022  0.334
2013 Cheng AW, Wang H, Yang H, Shi L, Katz Y, Theunissen TW, Rangarajan S, Shivalila CS, Dadon DB, Jaenisch R. Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system. Cell Research. 23: 1163-71. PMID 23979020 DOI: 10.1038/Cr.2013.122  0.361
2013 Faddah DA, Wang H, Cheng AW, Katz Y, Buganim Y, Jaenisch R. Single-cell analysis reveals that expression of nanog is biallelic and equally variable as that of other pluripotency factors in mouse ESCs. Cell Stem Cell. 13: 23-9. PMID 23827708 DOI: 10.1016/J.Stem.2013.04.019  0.449
2013 Huang H, Jiang X, Li Z, Li Y, Song CX, He C, Sun M, Chen P, Gurbuxani S, Wang J, Hong GM, Elkahloun AG, Arnovitz S, Wang J, Szulwach K, ... ... Jaenisch R, et al. TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 11994-9. PMID 23818607 DOI: 10.1073/Pnas.1310656110  0.433
2013 Torikai H, Reik A, Soldner F, Warren EH, Yuen C, Zhou Y, Crossland DL, Huls H, Littman N, Zhang Z, Tykodi SS, Kebriaei P, Lee DA, Miller JC, Rebar EJ, ... ... Jaenisch R, et al. Toward eliminating HLA class I expression to generate universal cells from allogeneic donors. Blood. 122: 1341-9. PMID 23741009 DOI: 10.1182/Blood-2013-03-478255  0.366
2013 Buganim Y, Faddah DA, Jaenisch R. Mechanisms and models of somatic cell reprogramming. Nature Reviews. Genetics. 14: 427-39. PMID 23681063 DOI: 10.1038/nrg3473  0.315
2013 Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell. 153: 910-8. PMID 23643243 DOI: 10.1016/J.Cell.2013.04.025  0.364
2013 Piccolo FM, Bagci H, Brown KE, Landeira D, Soza-Ried J, Feytout A, Mooijman D, Hajkova P, Leitch HG, Tada T, Kriaucionis S, Dawlaty MM, Jaenisch R, Merkenschlager M, Fisher AG. Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion. Molecular Cell. 49: 1023-33. PMID 23453809 DOI: 10.1016/j.molcel.2013.01.032  0.341
2013 Lodato MA, Ng CW, Wamstad JA, Cheng AW, Thai KK, Fraenkel E, Jaenisch R, Boyer LA. SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state. Plos Genetics. 9: e1003288. PMID 23437007 DOI: 10.1371/Journal.Pgen.1003288  0.826
2013 Dawlaty MM, Breiling A, Le T, Raddatz G, Barrasa MI, Cheng AW, Gao Q, Powell BE, Li Z, Xu M, Faull KF, Lyko F, Jaenisch R. Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development. Developmental Cell. 24: 310-23. PMID 23352810 DOI: 10.1016/J.Devcel.2012.12.015  0.532
2013 Avalos AM, Kirak O, Oelkers JM, Pils MC, Kim YM, Ottinger M, Jaenisch R, Ploegh HL, Brinkmann MM. Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice. Journal of Immunology (Baltimore, Md. : 1950). 190: 695-702. PMID 23241879 DOI: 10.4049/Jimmunol.1202342  0.314
2013 Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y. Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium. Development (Cambridge, England). 140: 66-75. PMID 23222438 DOI: 10.1242/Jcs.130047  0.371
2013 Ntziachristos P, Tsirigos A, Trimarchi T, Loizou E, Luyao X, Vlierberghe PV, King B, Welstead G, Mullighan C, Jaenisch R, Ferrando A, Aifantis I. Abstract A07: Characterizing the specific oncogenic and tumor suppressor roles of H3K27me3 epigenetic modulators in T cell leukemia Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A07  0.371
2013 Ricklefs F, Hua X, Velden J, Kirak O, Jaenisch R, Weissman I, Reichenspurner H. Immunobiology of embryonic stem cells: Foreign mtDNA as an immunological barrier in SCNT derived embryonic stem cells transplantation The Thoracic and Cardiovascular Surgeon. 61. DOI: 10.1055/S-0032-1332452  0.388
2013 Yamanaka S, Wagers A, Muotri A, Srivastava D, Melton D, Blanpain C, Gurdon J, Fuchs E, Jaenisch R. XStem cells in translation Cell. 153: X1177-1179. DOI: 10.1016/J.Cell.2013.05.036  0.367
2012 Buganim Y, Faddah DA, Cheng AW, Itskovich E, Markoulaki S, Ganz K, Klemm SL, van Oudenaarden A, Jaenisch R. Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase. Cell. 150: 1209-22. PMID 22980981 DOI: 10.1016/j.cell.2012.08.023  0.305
2012 Buganim Y, Itskovich E, Hu YC, Cheng AW, Ganz K, Sarkar S, Fu D, Welstead GG, Page DC, Jaenisch R. Direct reprogramming of fibroblasts into embryonic Sertoli-like cells by defined factors. Cell Stem Cell. 11: 373-86. PMID 22958931 DOI: 10.1016/J.Stem.2012.07.019  0.452
2012 Dougan SK, Ogata S, Hu CC, Grotenbreg GM, Guillen E, Jaenisch R, Ploegh HL. IgG1+ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 13739-44. PMID 22869725 DOI: 10.1073/Pnas.1210273109  0.335
2012 Welstead GG, Creyghton MP, Bilodeau S, Cheng AW, Markoulaki S, Young RA, Jaenisch R. X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner. Proceedings of the National Academy of Sciences of the United States of America. 109: 13004-9. PMID 22826230 DOI: 10.1073/Pnas.1210787109  0.535
2012 Hua X, Deuse T, Velden J, Kirak O, Jaenisch R, Weissman I, Ricklefs F, Reichenspurner H, Robbins RC, Schrepfer S. Immunobiology of SCNT Derived Embryonic Stem Cells: Pivotal Role of mtDNA in Rejection of Transplanted Stem Cells Transplantation Journal. 94: 113. DOI: 10.1097/00007890-201211271-00208  0.38
2012 Hua X, Deuse T, Velden J, Kirak O, Jaenisch R, Weissman I, Ricklefs F, Reichenspurner H, Robbins R, Schrepfer S. 330 Regenerative Therapy after Myocardial Infarction: Role of mtDNA in SCNT Derived Embryonic Stem Cells The Journal of Heart and Lung Transplantation. 31: S117. DOI: 10.1016/J.Healun.2012.01.338  0.338
2011 Carey BW, Markoulaki S, Hanna JH, Faddah DA, Buganim Y, Kim J, Ganz K, Steine EJ, Cassady JP, Creyghton MP, Welstead GG, Gao Q, Jaenisch R. Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells. Cell Stem Cell. 9: 588-98. PMID 22136932 DOI: 10.1016/J.Stem.2011.11.003  0.449
2011 Saha K, Mei Y, Reisterer CM, Pyzocha NK, Yang J, Muffat J, Davies MC, Alexander MR, Langer R, Anderson DG, Jaenisch R. Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions. Proceedings of the National Academy of Sciences of the United States of America. 108: 18714-9. PMID 22065768 DOI: 10.1073/Pnas.1114854108  0.761
2011 Kim J, Su SC, Wang H, Cheng AW, Cassady JP, Lodato MA, Lengner CJ, Chung CY, Dawlaty MM, Tsai LH, Jaenisch R. Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell. 9: 413-9. PMID 22019014 DOI: 10.1016/J.Stem.2011.09.011  0.782
2011 Gao Q, Steine EJ, Barrasa MI, Hockemeyer D, Pawlak M, Fu D, Reddy S, Bell GW, Jaenisch R. Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 108: 18061-6. PMID 22011581 DOI: 10.1073/Pnas.1114946108  0.672
2011 Major T, Menon J, Auyeung G, Soldner F, Hockemeyer D, Jaenisch R, Tabar V. Transgene excision has no impact on in vivo integration of human iPS derived neural precursors. Plos One. 6: e24687. PMID 21961042 DOI: 10.1371/Journal.Pone.0024687  0.704
2011 Medeiros LA, Dennis LM, Gill ME, Houbaviy H, Markoulaki S, Fu D, White AC, Kirak O, Sharp PA, Page DC, Jaenisch R. Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects. Proceedings of the National Academy of Sciences of the United States of America. 108: 14163-8. PMID 21844366 DOI: 10.1073/Pnas.1111241108  0.468
2011 Dawlaty MM, Ganz K, Powell BE, Hu YC, Markoulaki S, Cheng AW, Gao Q, Kim J, Choi SW, Page DC, Jaenisch R. Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell. 9: 166-75. PMID 21816367 DOI: 10.1016/J.Stem.2011.07.010  0.407
2011 Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, ... ... Jaenisch R, et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell. 146: 318-31. PMID 21757228 DOI: 10.1016/J.Cell.2011.06.019  0.808
2011 Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, ... ... Jaenisch R, et al. Genetic engineering of human pluripotent cells using TALE nucleases. Nature Biotechnology. 29: 731-4. PMID 21738127 DOI: 10.1038/Nbt.1927  0.718
2011 Pawlak M, Jaenisch R. De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes & Development. 25: 1035-40. PMID 21576263 DOI: 10.1101/Gad.2039011  0.437
2011 Zheng GX, Ravi A, Calabrese JM, Medeiros LA, Kirak O, Dennis LM, Jaenisch R, Burge CB, Sharp PA. A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells. Plos Genetics. 7: e1002054. PMID 21573140 DOI: 10.1371/Journal.Pgen.1002054  0.475
2011 Kim J, Lengner CJ, Kirak O, Hanna J, Cassady JP, Lodato MA, Wu S, Faddah DA, Steine EJ, Gao Q, Fu D, Dawlaty M, Jaenisch R. Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors. Stem Cells (Dayton, Ohio). 29: 992-1000. PMID 21563275 DOI: 10.1002/Stem.641  0.792
2011 Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, ... Jaenisch R, et al. Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells. Angewandte Chemie (International Ed. in English). 50: 5734-6. PMID 21547985 DOI: 10.1002/Anie.201101042  0.416
2011 Steine EJ, Ehrich M, Bell GW, Raj A, Reddy S, van Oudenaarden A, Jaenisch R, Linhart HG. Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer. The Journal of Clinical Investigation. 121: 1748-52. PMID 21490393 DOI: 10.1172/Jci43169  0.399
2010 Hockemeyer D, Jaenisch R. Gene targeting in human pluripotent cells. Cold Spring Harbor Symposia On Quantitative Biology. 75: 201-9. PMID 21209393 DOI: 10.1101/Sqb.2010.75.021  0.738
2010 Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proceedings of the National Academy of Sciences of the United States of America. 107: 21931-6. PMID 21106759 DOI: 10.1073/Pnas.1016071107  0.808
2010 Kirak O, Frickel EM, Grotenbreg GM, Suh H, Jaenisch R, Ploegh HL. Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT. Journal of Visualized Experiments : Jove. PMID 20972401 DOI: 10.3791/2168  0.4
2010 Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL. T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell. Proceedings of the National Academy of Sciences of the United States of America. 107: 18939-43. PMID 20956329 DOI: 10.1073/Pnas.1013230107  0.418
2010 Hargus G, Cooper O, Deleidi M, Levy A, Lee K, Marlow E, Yow A, Soldner F, Hockemeyer D, Hallett PJ, Osborn T, Jaenisch R, Isacson O. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proceedings of the National Academy of Sciences of the United States of America. 107: 15921-6. PMID 20798034 DOI: 10.1073/Pnas.1010209107  0.688
2010 Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH. Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes. Journal of Immunology (Baltimore, Md. : 1950). 185: 3564-73. PMID 20709953 DOI: 10.4049/Jimmunol.0903098  0.373
2010 Guenther MG, Frampton GM, Soldner F, Hockemeyer D, Mitalipova M, Jaenisch R, Young RA. Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. Cell Stem Cell. 7: 249-57. PMID 20682450 DOI: 10.1016/J.Stem.2010.06.015  0.767
2010 Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, ... ... Jaenisch R, et al. Epigenetic memory in induced pluripotent stem cells. Nature. 467: 285-90. PMID 20644535 DOI: 10.1038/Nature09342  0.45
2010 Staerk J, Dawlaty MM, Gao Q, Maetzel D, Hanna J, Sommer CA, Mostoslavsky G, Jaenisch R. Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell Stem Cell. 7: 20-4. PMID 20621045 DOI: 10.1016/J.Stem.2010.06.002  0.412
2010 DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, ... ... Jaenisch R, et al. Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. Genome Research. 20: 1133-42. PMID 20508142 DOI: 10.1101/Gr.106773.110  0.691
2010 Lengner CJ, Gimelbrant AA, Erwin JA, Cheng AW, Guenther MG, Welstead GG, Alagappan R, Frampton GM, Xu P, Muffat J, Santagata S, Powers D, Barrett CB, Young RA, Lee JT, ... Jaenisch R, et al. Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell. 141: 872-83. PMID 20471072 DOI: 10.1016/J.Cell.2010.04.010  0.813
2010 Hanna J, Cheng AW, Saha K, Kim J, Lengner CJ, Soldner F, Cassady JP, Muffat J, Carey BW, Jaenisch R. Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proceedings of the National Academy of Sciences of the United States of America. 107: 9222-7. PMID 20442331 DOI: 10.1073/Pnas.1004584107  0.777
2010 Namekawa SH, Payer B, Huynh KD, Jaenisch R, Lee JT. Two-step imprinted X inactivation: repeat versus genic silencing in the mouse. Molecular and Cellular Biology. 30: 3187-205. PMID 20404085 DOI: 10.1128/Mcb.00227-10  0.546
2010 Kirak O, Frickel EM, Grotenbreg GM, Suh H, Jaenisch R, Ploegh HL. Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT. Science (New York, N.Y.). 328: 243-8. PMID 20378817 DOI: 10.1126/Science.1178590  0.361
2010 Carette JE, Pruszak J, Varadarajan M, Blomen VA, Gokhale S, Camargo FD, Wernig M, Jaenisch R, Brummelkamp TR. Generation of iPSCs from cultured human malignant cells. Blood. 115: 4039-42. PMID 20233975 DOI: 10.1182/Blood-2009-07-231845  0.684
2010 Dressel R, Nolte J, Elsner L, Novota P, Guan K, Streckfuss-Bömeke K, Hasenfuss G, Jaenisch R, Engel W. Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2164-77. PMID 20145206 DOI: 10.1096/Fj.09-134957  0.414
2010 Carey BW, Markoulaki S, Beard C, Hanna J, Jaenisch R. Single-gene transgenic mouse strains for reprogramming adult somatic cells. Nature Methods. 7: 56-9. PMID 20010831 DOI: 10.1038/Nmeth.1410  0.44
2009 Bröske AM, Vockentanz L, Kharazi S, Huska MR, Mancini E, Scheller M, Kuhl C, Enns A, Prinz M, Jaenisch R, Nerlov C, Leutz A, Andrade-Navarro MA, Jacobsen SE, Rosenbauer F. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nature Genetics. 41: 1207-15. PMID 19801979 DOI: 10.1038/Ng.463  0.433
2009 Kuzmenkin A, Liang H, Xu G, Pfannkuche K, Eichhorn H, Fatima A, Luo H, Saric T, Wernig M, Jaenisch R, Hescheler J. Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4168-80. PMID 19703934 DOI: 10.1096/Fj.08-128546  0.66
2009 Hockemeyer D, Soldner F, Beard C, Gao Q, Mitalipova M, DeKelver RC, Katibah GE, Amora R, Boydston EA, Zeitler B, Meng X, Miller JC, Zhang L, Rebar EJ, Gregory PD, ... ... Jaenisch R, et al. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nature Biotechnology. 27: 851-7. PMID 19680244 DOI: 10.1038/Nbt.1562  0.733
2009 Pfannkuche K, Liang H, Hannes T, Xi J, Fatima A, Nguemo F, Matzkies M, Wernig M, Jaenisch R, Pillekamp F, Halbach M, Schunkert H, Sarić T, Hescheler J, Reppel M. Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 24: 73-86. PMID 19590195 DOI: 10.1159/000227815  0.638
2009 Nosho K, Shima K, Irahara N, Kure S, Baba Y, Kirkner GJ, Chen L, Gokhale S, Hazra A, Spiegelman D, Giovannucci EL, Jaenisch R, Fuchs CS, Ogino S. DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3663-71. PMID 19470733 DOI: 10.1158/1078-0432.Ccr-08-2383  0.316
2009 Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, Markoulaki S, Hanna J, Lairson LL, Charette BD, Bouchez LC, Bollong M, Kunick C, Brinker A, Cho CY, Schultz PG, ... Jaenisch R, et al. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America. 106: 8912-7. PMID 19447925 DOI: 10.1073/Pnas.0903860106  0.394
2009 Hanna J, Markoulaki S, Mitalipova M, Cheng AW, Cassady JP, Staerk J, Carey BW, Lengner CJ, Foreman R, Love J, Gao Q, Kim J, Jaenisch R. Metastable pluripotent states in NOD-mouse-derived ESCs. Cell Stem Cell. 4: 513-24. PMID 19427283 DOI: 10.1016/J.Stem.2009.04.015  0.432
2009 Han DW, Do JT, Araúzo-Bravo MJ, Lee SH, Meissner A, Lee HT, Jaenisch R, Schöler HR. Epigenetic hierarchy governing Nestin expression. Stem Cells (Dayton, Ohio). 27: 1088-97. PMID 19415779 DOI: 10.1002/Stem.43  0.424
2009 Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG, Hargus G, Blak A, Cooper O, Mitalipova M, Isacson O, Jaenisch R. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell. 136: 964-77. PMID 19269371 DOI: 10.1016/J.Cell.2009.02.013  0.693
2009 Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S. Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell. 4: 200-1; author reply . PMID 19265657 DOI: 10.1016/J.Stem.2009.02.009  0.764
2009 Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature. 458: 223-7. PMID 19182780 DOI: 10.1038/Nature07672  0.368
2009 Markoulaki S, Hanna J, Beard C, Carey BW, Cheng AW, Lengner CJ, Dausman JA, Fu D, Gao Q, Wu S, Cassady JP, Jaenisch R. Transgenic mice with defined combinations of drug-inducible reprogramming factors. Nature Biotechnology. 27: 169-71. PMID 19151700 DOI: 10.1038/Nbt.1520  0.396
2009 Meissner A, Eminli S, Jaenisch R. Derivation and manipulation of murine embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 482: 3-19. PMID 19089346 DOI: 10.1007/978-1-59745-060-7_1  0.434
2009 Foudi A, Hochedlinger K, Van Buren D, Schindler JW, Jaenisch R, Carey V, Hock H. Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells. Nature Biotechnology. 27: 84-90. PMID 19060879 DOI: 10.1038/Nbt.1517  0.376
2009 Linhart HG, Troen A, Bell GW, Cantu E, Chao WH, Moran E, Steine E, He T, Jaenisch R. Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations. Gastroenterology. 136: 227-235.e3. PMID 18992744 DOI: 10.1053/J.Gastro.2008.10.016  0.357
2009 Hanna J, Markoulaki S, Mitalipova M, Cheng AW, Cassady JP, Staerk J, Carey BW, Lengner CJ, Foreman R, Love J, Gao Q, Kim J, Jaenisch R. Metastable Pluripotent States in NOD-Mouse-Derived ESCs (DOI:10.1016/j.stem.2008.08.014) Cell Stem Cell. 5: 124. DOI: 10.1016/J.Stem.2009.06.007  0.344
2009 Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG, Hargus G, Blak A, Cooper O, Mitalipova M, Isacson O, Jaenisch R. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors (DOI:10.1016/j.cell.2009.02.013) Cell. 137: 1356. DOI: 10.1016/j.cell.2009.06.017  0.68
2009 Hockemeyer D, Soldner F, Jaenisch R. Direct Reprogramming of Somatic Cells to a Pluripotent State Essentials of Stem Cell Biology. 29-31. DOI: 10.1016/B978-0-12-374729-7.00004-4  0.672
2008 Creyghton MP, Markoulaki S, Levine SS, Hanna J, Lodato MA, Sha K, Young RA, Jaenisch R, Boyer LA. H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment. Cell. 135: 649-61. PMID 18992931 DOI: 10.1016/J.Cell.2008.09.056  0.822
2008 Hockemeyer D, Soldner F, Cook EG, Gao Q, Mitalipova M, Jaenisch R. A drug-inducible system for direct reprogramming of human somatic cells to pluripotency. Cell Stem Cell. 3: 346-53. PMID 18786421 DOI: 10.1016/J.Stem.2008.08.014  0.72
2008 Green JJ, Zhou BY, Mitalipova MM, Beard C, Langer R, Jaenisch R, Anderson DG. Nanoparticles for gene transfer to human embryonic stem cell colonies. Nano Letters. 8: 3126-30. PMID 18754690 DOI: 10.1021/Nl8012665  0.355
2008 Mathur D, Danford TW, Boyer LA, Young RA, Gifford DK, Jaenisch R. Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET. Genome Biology. 9: R126. PMID 18700969 DOI: 10.1186/Gb-2008-9-8-R126  0.757
2008 Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, ... ... Jaenisch R, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell. 134: 521-33. PMID 18692474 DOI: 10.1016/J.Cell.2008.07.020  0.787
2008 Marson A, Foreman R, Chevalier B, Bilodeau S, Kahn M, Young RA, Jaenisch R. Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell. 3: 132-5. PMID 18682236 DOI: 10.1016/J.Stem.2008.06.019  0.647
2008 Kronenberg G, Harms C, Sobol RW, Cardozo-Pelaez F, Linhart H, Winter B, Balkaya M, Gertz K, Gay SB, Cox D, Eckart S, Ahmadi M, Juckel G, Kempermann G, Hellweg R, ... ... Jaenisch R, et al. Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7219-30. PMID 18614692 DOI: 10.1523/Jneurosci.0940-08.2008  0.314
2008 Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 454: 766-70. PMID 18600261 DOI: 10.1038/Nature07107  0.662
2008 Wernig M, Lengner CJ, Hanna J, Lodato MA, Steine E, Foreman R, Staerk J, Markoulaki S, Jaenisch R. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nature Biotechnology. 26: 916-24. PMID 18594521 DOI: 10.1038/Nbt1483  0.816
2008 Markoulaki S, Meissner A, Jaenisch R. Somatic cell nuclear transfer and derivation of embryonic stem cells in the mouse. Methods (San Diego, Calif.). 45: 101-14. PMID 18593608 DOI: 10.1016/J.Ymeth.2008.04.002  0.457
2008 Hirasawa R, Chiba H, Kaneda M, Tajima S, Li E, Jaenisch R, Sasaki H. Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes & Development. 22: 1607-16. PMID 18559477 DOI: 10.1101/Gad.1667008  0.362
2008 Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis. Nature. 454: 49-55. PMID 18509334 DOI: 10.1038/Nature07056  0.694
2008 Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell. 133: 250-64. PMID 18423197 DOI: 10.1016/J.Cell.2008.03.028  0.62
2008 Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, Broccoli V, Constantine-Paton M, Isacson O, Jaenisch R. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 5856-61. PMID 18391196 DOI: 10.1073/Pnas.0801677105  0.651
2008 Fouse SD, Shen Y, Pellegrini M, Cole S, Meissner A, Van Neste L, Jaenisch R, Fan G. Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell. 2: 160-9. PMID 18371437 DOI: 10.1016/J.Stem.2007.12.011  0.792
2008 Brambrink T, Foreman R, Welstead GG, Lengner CJ, Wernig M, Suh H, Jaenisch R. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell. 2: 151-9. PMID 18371436 DOI: 10.1016/J.Stem.2008.01.004  0.66
2008 Wernig M, Meissner A, Cassady JP, Jaenisch R. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell. 2: 10-2. PMID 18371415 DOI: 10.1016/J.Stem.2007.12.001  0.622
2008 Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, Newman J, Bronson RT, Crowley D, Stone JR, Jaenisch R, Sharp PA, Jacks T. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 132: 875-86. PMID 18329372 DOI: 10.1016/J.Cell.2008.02.019  0.427
2008 Jaenisch R, Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell. 132: 567-82. PMID 18295576 DOI: 10.1016/J.Cell.2008.01.015  0.564
2008 Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis (Nature (2008) 454, (49-55)) Nature. 454: 794. DOI: 10.1038/Nature07196  0.578
2008 Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency (DOI:10.1016/j.cell.2008.03.028) Cell. 134: 365. DOI: 10.1016/j.cell.2008.07.013  0.59
2007 Hyun I, Hochedlinger K, Jaenisch R, Yamanaka S. New advances in iPS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell. 1: 367-8. PMID 18371375 DOI: 10.1016/J.Stem.2007.09.006  0.364
2007 Kim K, Ng K, Rugg-Gunn PJ, Shieh JH, Kirak O, Jaenisch R, Wakayama T, Moore MA, Pedersen RA, Daley GQ. Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell Stem Cell. 1: 346-52. PMID 18371368 DOI: 10.1016/J.Stem.2007.07.001  0.413
2007 Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell. 1: 55-70. PMID 18371336 DOI: 10.1016/J.Stem.2007.05.014  0.832
2007 Lengner CJ, Camargo FD, Hochedlinger K, Welstead GG, Zaidi S, Gokhale S, Scholer HR, Tomilin A, Jaenisch R. Oct4 expression is not required for mouse somatic stem cell self-renewal. Cell Stem Cell. 1: 403-15. PMID 18159219 DOI: 10.1016/J.Stem.2007.07.020  0.441
2007 Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (New York, N.Y.). 318: 1920-3. PMID 18063756 DOI: 10.1126/Science.1152092  0.685
2007 Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, Meissner A, Jaenisch R. Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes & Development. 21: 3110-22. PMID 18056424 DOI: 10.1101/Gad.1594007  0.372
2007 Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R, Brummelkamp TR. YAP1 increases organ size and expands undifferentiated progenitor cells. Current Biology : Cb. 17: 2054-60. PMID 17980593 DOI: 10.1016/J.Cub.2007.10.039  0.406
2007 Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, Jaenisch R, Laird PW, Akbarian S. DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. Plos One. 2: e895. PMID 17878930 DOI: 10.1371/Journal.Pone.0000895  0.668
2007 Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nature Biotechnology. 25: 1177-81. PMID 17724450 DOI: 10.1038/Nbt1335  0.673
2007 Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA. A chromatin landmark and transcription initiation at most promoters in human cells. Cell. 130: 77-88. PMID 17632057 DOI: 10.1016/J.Cell.2007.05.042  0.752
2007 Serwold T, Hochedlinger K, Inlay MA, Jaenisch R, Weissman IL. Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes. Journal of Immunology (Baltimore, Md. : 1950). 179: 928-38. PMID 17617584 DOI: 10.4049/Jimmunol.179.2.928  0.38
2007 Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim TK, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, ... ... Jaenisch R, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 448: 553-60. PMID 17603471 DOI: 10.1038/Nature06008  0.669
2007 Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature. 448: 318-24. PMID 17554336 DOI: 10.1038/Nature05944  0.695
2007 Nguyen S, Meletis K, Fu D, Jhaveri S, Jaenisch R. Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 1663-76. PMID 17477386 DOI: 10.1002/Dvdy.21176  0.351
2007 Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nature Genetics. 39: 380-5. PMID 17259983 DOI: 10.1038/Ng1969  0.36
2007 Boyer LA, Jaenisch R, Mitalipova M. Genetic and Epigenetic Analysis of Human Embryonic Stem Cell Human Embryonic Stem Cells: the Practical Handbook. 107-119. DOI: 10.1002/9780470511619.ch8  0.688
2006 Savarese F, Flahndorfer K, Jaenisch R, Busslinger M, Wutz A. Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Molecular and Cellular Biology. 26: 7167-77. PMID 16980619 DOI: 10.1128/Mcb.00810-06  0.447
2006 Boyer LA, Mathur D, Jaenisch R. Molecular control of pluripotency. Current Opinion in Genetics & Development. 16: 455-62. PMID 16920351 DOI: 10.1016/J.Gde.2006.08.009  0.741
2006 Meissner A, Jaenisch R. Mammalian nuclear transfer. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2460-9. PMID 16881069 DOI: 10.1002/Dvdy.20915  0.384
2006 Blelloch R, Wang Z, Meissner A, Pollard S, Smith A, Jaenisch R. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem Cells (Dayton, Ohio). 24: 2007-13. PMID 16709876 DOI: 10.1634/Stemcells.2006-0050  0.339
2006 Shimazu K, Zhao M, Sakata K, Akbarian S, Bates B, Jaenisch R, Lu B. NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis. Learning & Memory (Cold Spring Harbor, N.Y.). 13: 307-15. PMID 16705139 DOI: 10.1101/Lm.76006  0.302
2006 Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 125: 315-26. PMID 16630819 DOI: 10.1016/J.Cell.2006.02.041  0.815
2006 Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, ... ... Jaenisch R, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 125: 301-13. PMID 16630818 DOI: 10.1016/J.Cell.2006.02.043  0.778
2006 Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, ... Jaenisch R, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 441: 349-53. PMID 16625203 DOI: 10.1038/Nature04733  0.831
2006 Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R. Suppression of intestinal neoplasia by deletion of Dnmt3b. Molecular and Cellular Biology. 26: 2976-83. PMID 16581773 DOI: 10.1128/Mcb.26.8.2976-2983.2006  0.71
2006 Jaenisch R, Meissner A. Politically correct human embryonic stem cells? The New England Journal of Medicine. 354: 1208-9; author reply. PMID 16540629 DOI: 10.1056/Nejmc055530  0.375
2006 Yang X, Eggan K, Seidel G, Jaenisch R, Melton D. A simple system of checks and balances to cut fraud. Nature. 439: 782. PMID 16482128 DOI: 10.1038/439782B  0.505
2006 Chang Q, Khare G, Dani V, Nelson S, Jaenisch R. The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. Neuron. 49: 341-8. PMID 16446138 DOI: 10.1016/J.Neuron.2005.12.027  0.319
2006 Brambrink T, Hochedlinger K, Bell G, Jaenisch R. ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable. Proceedings of the National Academy of Sciences of the United States of America. 103: 933-8. PMID 16418286 DOI: 10.1073/Pnas.0510485103  0.464
2006 Beard C, Hochedlinger K, Plath K, Wutz A, Jaenisch R. Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis (New York, N.Y. : 2000). 44: 23-8. PMID 16400644 DOI: 10.1002/Gene.20180  0.744
2006 Meissner A, Jaenisch R. Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts. Nature. 439: 212-5. PMID 16227971 DOI: 10.1038/Nature04257  0.394
2006 Gemelli T, Berton O, Nelson ED, Perrotti LI, Jaenisch R, Monteggia LM. Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice. Biological Psychiatry. 59: 468-76. PMID 16199017 DOI: 10.1016/J.Biopsych.2005.07.025  0.324
2005 Holm TM, Jackson-Grusby L, Brambrink T, Yamada Y, Rideout WM, Jaenisch R. Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell. 8: 275-85. PMID 16226703 DOI: 10.1016/J.Ccr.2005.09.007  0.763
2005 Meissner A, Gnirke A, Bell GW, Ramsahoye B, Lander ES, Jaenisch R. Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Research. 33: 5868-77. PMID 16224102 DOI: 10.1093/Nar/Gki901  0.335
2005 Yamada Y, Jackson-Grusby L, Linhart H, Meissner A, Eden A, Lin H, Jaenisch R. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 13580-5. PMID 16174748 DOI: 10.1073/Pnas.0506612102  0.723
2005 Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 122: 947-56. PMID 16153702 DOI: 10.1016/J.Cell.2005.08.020  0.766
2005 Dani VS, Chang Q, Maffei A, Turrigiano GG, Jaenisch R, Nelson SB. Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America. 102: 12560-5. PMID 16116096 DOI: 10.1073/Pnas.0506071102  0.314
2005 Jaenisch R, Hochedlinger K, Eggan K. Nuclear cloning, epigenetic reprogramming and cellular differentiation. Novartis Foundation Symposium. 265: 107-18; discussion 1. PMID 16050253  0.638
2005 Houbaviy HB, Dennis L, Jaenisch R, Sharp PA. Characterization of a highly variable eutherian microRNA gene. Rna (New York, N.Y.). 11: 1245-57. PMID 15987809 DOI: 10.1261/Rna.2890305  0.496
2005 Lyckman AW, Fan G, Rios M, Jaenisch R, Sur M. Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor. Visual Neuroscience. 22: 27-36. PMID 15842738 DOI: 10.1017/S095252380522103X  0.485
2005 Ma Y, Jacobs SB, Jackson-Grusby L, Mastrangelo MA, Torres-Betancourt JA, Jaenisch R, Rasmussen TP. DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A. Journal of Cell Science. 118: 1607-16. PMID 15784683 DOI: 10.1242/Jcs.02291  0.744
2004 Jaenisch R, Hochedlinger K, Blelloch R, Yamada Y, Baldwin K, Eggan K. Nuclear cloning, epigenetic reprogramming, and cellular differentiation. Cold Spring Harbor Symposia On Quantitative Biology. 69: 19-27. PMID 16117629 DOI: 10.1002/0470091452.Ch9  0.674
2004 Plath K, Talbot D, Hamer KM, Otte AP, Yang TP, Jaenisch R, Panning B. Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome. The Journal of Cell Biology. 167: 1025-35. PMID 15596546 DOI: 10.1083/Jcb.200409026  0.793
2004 Mihich E, Jaenisch R. Sixteenth Annual Pezcoller Symposium: stem cells and epigenesis in cancer. Cancer Research. 64: 8474-7. PMID 15548721 DOI: 10.1158/0008-5472.Can-04-2625  0.403
2004 Wang Z, Jaenisch R. At most three ES cells contribute to the somatic lineages of chimeric mice and of mice produced by ES-tetraploid complementation. Developmental Biology. 275: 192-201. PMID 15464582 DOI: 10.1016/J.Ydbio.2004.06.026  0.412
2004 Begum NA, Kinoshita K, Kakazu N, Muramatsu M, Nagaoka H, Shinkura R, Biniszkiewicz D, Boyer LA, Jaenisch R, Honjo T. Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch. Science (New York, N.Y.). 305: 1160-3. PMID 15326357 DOI: 10.1126/Science.1098444  0.656
2004 Blelloch RH, Hochedlinger K, Yamada Y, Brennan C, Kim M, Mintz B, Chin L, Jaenisch R. Nuclear cloning of embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 13985-90. PMID 15306687 DOI: 10.1073/Pnas.0405015101  0.635
2004 Hochedlinger K, Blelloch R, Brennan C, Yamada Y, Kim M, Chin L, Jaenisch R. Reprogramming of a melanoma genome by nuclear transplantation. Genes & Development. 18: 1875-85. PMID 15289459 DOI: 10.1101/Gad.1213504  0.392
2004 Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, Van Parijs L, Jaenisch R, Jacks T. Cre-lox-regulated conditional RNA interference from transgenes. Proceedings of the National Academy of Sciences of the United States of America. 101: 10380-5. PMID 15240889 DOI: 10.1073/Pnas.0403954101  0.501
2004 Endres M, Biniszkiewicz D, Sobol RW, Harms C, Ahmadi M, Lipski A, Katchanov J, Mergenthaler P, Dirnagl U, Wilson SH, Meisel A, Jaenisch R. Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. The Journal of Clinical Investigation. 113: 1711-21. PMID 15199406 DOI: 10.1172/Jci20926  0.345
2004 Hochedlinger K, Rideout WM, Kyba M, Daley GQ, Blelloch R, Jaenisch R. Nuclear transplantation, embryonic stem cells and the potential for cell therapy. The Hematology Journal : the Official Journal of the European Haematology Association / Eha. 5: S114-7. PMID 15190291 DOI: 10.1038/Sj.Thj.6200435  0.302
2004 Natoli TA, Alberta JA, Bortvin A, Taglienti ME, Menke DB, Loring J, Jaenisch R, Page DC, Housman DE, Kreidberg JA. Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis. Developmental Biology. 268: 429-40. PMID 15063178 DOI: 10.1016/J.Ydbio.2003.12.033  0.696
2004 Eggan K, Baldwin K, Tackett M, Osborne J, Gogos J, Chess A, Axel R, Jaenisch R. Mice cloned from olfactory sensory neurons. Nature. 428: 44-9. PMID 14990966 DOI: 10.1038/Nature02375  0.604
2003 Eggan K, Jaenisch R. Micromanipulating dosage compensation: understanding X-chromosome inactivation through nuclear transplantation. Seminars in Cell & Developmental Biology. 14: 349-58. PMID 15015742 DOI: 10.1016/J.Semcdb.2003.09.012  0.604
2003 Eggan K, Jaenisch R. Differentiation of F1 embryonic stem cells into viable male and female mice by tetraploid embryo complementation. Methods in Enzymology. 365: 25-39. PMID 14696335 DOI: 10.1016/S0076-6879(03)65002-0  0.647
2003 Chen WG, Chang Q, Lin Y, Meissner A, West AE, Griffith EC, Jaenisch R, Greenberg ME. Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science (New York, N.Y.). 302: 885-9. PMID 14593183 DOI: 10.1126/Science.1086446  0.341
2003 Brivanlou AH, Gage FH, Jaenisch R, Jessell T, Melton D, Rossant J. Stem cells. Setting standards for human embryonic stem cells. Science (New York, N.Y.). 300: 913-6. PMID 12738841 DOI: 10.1126/Science.1082940  0.412
2003 Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H, Jaenisch R. Induction of tumors in mice by genomic hypomethylation. Science (New York, N.Y.). 300: 489-92. PMID 12702876 DOI: 10.1126/Science.1083558  0.731
2003 Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 112: 645-57. PMID 12628185 DOI: 10.1016/S0092-8674(03)00154-5  0.596
2003 Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R, Page DC, Jaenisch R. Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development (Cambridge, England). 130: 1673-80. PMID 12620990 DOI: 10.1242/Dev.00366  0.651
2003 Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nature Genetics. 33: 245-54. PMID 12610534 DOI: 10.1038/Ng1089  0.384
2003 Seibler J, Zevnik B, Küter-Luks B, Andreas S, Kern H, Hennek T, Rode A, Heimann C, Faust N, Kauselmann G, Schoor M, Jaenisch R, Rajewsky K, Kühn R, Schwenk F. Rapid generation of inducible mouse mutants. Nucleic Acids Research. 31: e12. PMID 12582257 DOI: 10.1093/Nar/Gng012  0.387
2003 Endres M, Fan G, Hirt L, Jaenisch R. Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 150-3. PMID 12571446 DOI: 10.1097/01.Wcb.0000043949.67811.C6  0.481
2003 Fan G, Jaenisch R, Kucera J. Corrigendum to “a role for p75 receptor in neurotrophin-3 functioning during the development of limb proprioception” Neuroscience. 118: 879. DOI: 10.1016/S0306-4522(02)00914-4  0.434
2003 Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. Erratum: HIF-1α is essential for myeloid cell-mediated inflammation (Cell 112:5 (648)) Cell. 113. DOI: 10.1016/S0092-8674(03)00311-8  0.621
2002 Jaenisch R, Eggan K, Humpherys D, Rideout W, Hochedlinger K. Nuclear cloning, stem cells, and genomic reprogramming. Cloning and Stem Cells. 4: 389-396. PMID 12630413 DOI: 10.1089/153623002321025069  0.638
2002 McCarrey JR, Watson C, Atencio J, Ostermeier GC, Marahrens Y, Jaenisch R, Krawetz SA. X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse. Genesis (New York, N.Y. : 2000). 34: 257-66. PMID 12434336 DOI: 10.1002/Gene.10163  0.4
2002 Tudor M, Akbarian S, Chen RZ, Jaenisch R. Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain. Proceedings of the National Academy of Sciences of the United States of America. 99: 15536-41. PMID 12432090 DOI: 10.1073/Pnas.242566899  0.376
2002 Turner JM, Mahadevaiah SK, Elliott DJ, Garchon HJ, Pehrson JR, Jaenisch R, Burgoyne PS. Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist. Journal of Cell Science. 115: 4097-105. PMID 12356914 DOI: 10.1242/Jcs.00111  0.351
2002 Humpherys D, Eggan K, Akutsu H, Friedman A, Hochedlinger K, Yanagimachi R, Lander ES, Golub TR, Jaenisch R. Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei. Proceedings of the National Academy of Sciences of the United States of America. 99: 12889-94. PMID 12235366 DOI: 10.1073/Pnas.192433399  0.646
2002 Akbarian S, Rios M, Liu RJ, Gold SJ, Fong HF, Zeiler S, Coppola V, Tessarollo L, Jones KR, Nestler EJ, Aghajanian GK, Jaenisch R. Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4153-62. PMID 12019333 DOI: 10.1523/Jneurosci.22-10-04153.2002  0.301
2002 Eggan K, Rode A, Jentsch I, Samuel C, Hennek T, Tintrup H, Zevnik B, Erwin J, Loring J, Jackson-Grusby L, Speicher MR, Kuehn R, Jaenisch R. Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nature Biotechnology. 20: 455-9. PMID 11981557 DOI: 10.1038/Nbt0502-455  0.815
2002 Rideout WM, Hochedlinger K, Kyba M, Daley GQ, Jaenisch R. Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell. 109: 17-27. PMID 11955443 DOI: 10.1016/S0092-8674(02)00681-5  0.414
2002 Biniszkiewicz D, Gribnau J, Ramsahoye B, Gaudet F, Eggan K, Humpherys D, Mastrangelo MA, Jun Z, Walter J, Jaenisch R. Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Molecular and Cellular Biology. 22: 2124-35. PMID 11884600 DOI: 10.1128/Mcb.22.7.2124-2135.2002  0.634
2002 Possemato R, Eggan K, Moeller BJ, Jaenisch R, Jackson-Grusby L. Flp recombinase regulated lacZ expression at the ROSA26 locus. Genesis (New York, N.Y. : 2000). 32: 184-6. PMID 11857816 DOI: 10.1002/Gene.10039  0.783
2002 Wutz A, Rasmussen TP, Jaenisch R. Chromosomal silencing and localization are mediated by different domains of Xist RNA. Nature Genetics. 30: 167-74. PMID 11780141 DOI: 10.1038/Ng820  0.334
2002 Fan G, Copray S, Huang EJ, Jones K, Yan Q, Walro J, Jaenisch R, Kucera J. Formation of a full complement of cranial proprioceptors requires multiple neurotrophins Developmental Dynamics. 225: 602-602. DOI: 10.1002/Dvdy.10197  0.446
2001 Rasmussen TP, Wutz AP, Pehrson JR, Jaenisch RR. Expression of Xist RNA is sufficient to initiate macrochromatin body formation. Chromosoma. 110: 411-20. PMID 11734999 DOI: 10.1007/S004120100158  0.363
2001 Fan G, Siniaia M, Poon CS, Jaenisch R. Effect of DNA hypomethylation on neural control of respiration: a genetic model. Advances in Experimental Medicine and Biology. 499: 195-200. PMID 11729877 DOI: 10.1007/978-1-4615-1375-9_30  0.528
2001 Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, Makar KW, Pérez-Melgosa M, Sweetser MT, Schlissel MS, Nguyen S, Cherry SR, Tsai JH, Tucker SM, Weaver WM, Kelso A, ... Jaenisch R, et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity. 15: 763-74. PMID 11728338 DOI: 10.1016/S1074-7613(01)00227-8  0.428
2001 Endres M, Fan G, Meisel A, Dirnagl U, Jaenisch R. Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons. Neuroreport. 12: 3763-6. PMID 11726790 DOI: 10.1097/00001756-200112040-00032  0.513
2001 Akbarian S, Chen RZ, Gribnau J, Rasmussen TP, Fong H, Jaenisch R, Jones EG. Expression pattern of the Rett syndrome gene MeCP2 in primate prefrontal cortex. Neurobiology of Disease. 8: 784-91. PMID 11592848 DOI: 10.1006/Nbdi.2001.0420  0.303
2001 Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan RM, Jaenisch R. Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Molecular Endocrinology (Baltimore, Md.). 15: 1748-57. PMID 11579207 DOI: 10.1210/Mend.15.10.0706  0.468
2001 Akbarian S, Bates B, Liu RJ, Skirboll SL, Pejchal T, Coppola V, Sun LD, Fan G, Kucera J, Wilson MA, Tessarollo L, Kosofsky BE, Taylor JR, Bothwell M, Nestler EJ, ... ... Jaenisch R, et al. Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal. Molecular Psychiatry. 6: 593-604. PMID 11526474 DOI: 10.1038/Sj.Mp.4000897  0.485
2001 Rideout WM, Eggan K, Jaenisch R. Nuclear cloning and epigenetic reprogramming of the genome. Science (New York, N.Y.). 293: 1093-8. PMID 11498580 DOI: 10.1126/Science.1063206  0.652
2001 Humpherys D, Eggan K, Akutsu H, Hochedlinger K, Rideout WM, Biniszkiewicz D, Yanagimachi R, Jaenisch R. Epigenetic instability in ES cells and cloned mice. Science (New York, N.Y.). 293: 95-7. PMID 11441181 DOI: 10.1126/Science.1061402  0.661
2001 Csankovszki G, Nagy A, Jaenisch R. Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. The Journal of Cell Biology. 153: 773-84. PMID 11352938 DOI: 10.1083/Jcb.153.4.773  0.37
2001 Eggan K, Akutsu H, Loring J, Jackson-Grusby L, Klemm M, Rideout WM, Yanagimachi R, Jaenisch R. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proceedings of the National Academy of Sciences of the United States of America. 98: 6209-14. PMID 11331774 DOI: 10.1073/Pnas.101118898  0.802
2001 Chen RZ, Akbarian S, Tudor M, Jaenisch R. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nature Genetics. 27: 327-31. PMID 11242118 DOI: 10.1038/85906  0.373
2001 Haase VH, Glickman JN, Socolovsky M, Jaenisch R. Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 98: 1583-8. PMID 11171994 DOI: 10.1073/Pnas.98.4.1583  0.618
2001 Fan G, Beard C, Chen RZ, Csankovszki G, Sun Y, Siniaia M, Biniszkiewicz D, Bates B, Lee PP, Kuhn R, Trumpp A, Poon C, Wilson CB, Jaenisch R. DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 788-97. PMID 11157065 DOI: 10.1523/Jneurosci.21-03-00788.2001  0.566
2001 Jackson-Grusby L, Beard C, Possemato R, Tudor M, Fambrough D, Csankovszki G, Dausman J, Lee P, Wilson C, Lander E, Jaenisch R. Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nature Genetics. 27: 31-9. PMID 11137995 DOI: 10.1038/83730  0.759
2000 Eggan K, Akutsu H, Hochedlinger K, Rideout W, Yanagimachi R, Jaenisch R. X-Chromosome inactivation in cloned mouse embryos. Science (New York, N.Y.). 290: 1578-81. PMID 11090356 DOI: 10.1126/Science.290.5496.1578  0.583
2000 Cherry SR, Biniszkiewicz D, van Parijs L, Baltimore D, Jaenisch R. Retroviral expression in embryonic stem cells and hematopoietic stem cells. Molecular and Cellular Biology. 20: 7419-26. PMID 11003639 DOI: 10.1128/MCB.20.20.7419-7426.2000  0.519
2000 Rasmussen TP, Mastrangelo MA, Eden A, Pehrson JR, Jaenisch R. Dynamic relocalization of histone MacroH2A1 from centrosomes to inactive X chromosomes during X inactivation. The Journal of Cell Biology. 150: 1189-98. PMID 10974005 DOI: 10.1083/Jcb.150.5.1189  0.401
2000 Lyko F, Whittaker AJ, Orr-Weaver TL, Jaenisch R. The putative Drosophila methyltransferase gene dDnmt2 is contained in a transposon-like element and is expressed specifically in ovaries. Mechanisms of Development. 95: 215-7. PMID 10906465 DOI: 10.1016/S0925-4773(00)00325-7  0.373
2000 Cherry SR, Beard C, Jaenisch R, Baltimore D. V(D)J recombination is not activated by demethylation of the kappa locus. Proceedings of the National Academy of Sciences of the United States of America. 97: 8467-72. PMID 10880575 DOI: 10.1073/Pnas.150218497  0.523
2000 Fan G, Copray S, Huang EJ, Jones K, Yan Q, Walro J, Jaenisch R, Kucera J. Formation of a full complement of cranial proprioceptors requires multiple neurotrophins. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 218: 359-70. PMID 10842362 DOI: 10.1002/(Sici)1097-0177(200006)218:2<359::Aid-Dvdy9>3.0.Co;2-L  0.5
2000 Endres M, Meisel A, Biniszkiewicz D, Namura S, Prass K, Ruscher K, Lipski A, Jaenisch R, Moskowitz MA, Dirnagl U. DNA methyltransferase contributes to delayed ischemic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3175-81. PMID 10777781 DOI: 10.1523/Jneurosci.20-09-03175.2000  0.335
2000 Fan G, Egles C, Sun Y, Minichiello L, Renger JJ, Klein R, Liu G, Jaenisch R. Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities. Nature Neuroscience. 3: 350-7. PMID 10725924 DOI: 10.1038/73921  0.493
2000 Rideout WM, Wakayama T, Wutz A, Eggan K, Jackson-Grusby L, Dausman J, Yanagimachi R, Jaenisch R. Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nature Genetics. 24: 109-10. PMID 10655052 DOI: 10.1038/72753  0.776
2000 Endres M, Fan G, Hirt L, Fujii M, Matsushita K, Liu X, Jaenisch R, Moskowitz MA. Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 139-44. PMID 10616802 DOI: 10.1097/00004647-200001000-00018  0.473
1999 Lyko F, Ramsahoye BH, Kashevsky H, Tudor M, Mastrangelo MA, Orr-Weaver TL, Jaenisch R. Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila. Nature Genetics. 23: 363-6. PMID 10545955 DOI: 10.1038/15551  0.367
1999 Tudor M, Murray PJ, Onufryk C, Jaenisch R, Young RA. Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice. Genes & Development. 13: 2365-8. PMID 10500093 DOI: 10.1101/Gad.13.18.2365  0.53
1999 Tanaka M, Puchyr M, Gertsenstein M, Harpal K, Jaenisch R, Rossant J, Nagy A. Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation. Mechanisms of Development. 87: 129-42. PMID 10495277 DOI: 10.1016/S0925-4773(99)00158-6  0.401
1999 Rasmussen TP, Huang T, Mastrangelo MA, Loring J, Panning B, Jaenisch R. Messenger RNAs encoding mouse histone macroH2A1 isoforms are expressed at similar levels in male and female cells and result from alternative splicing. Nucleic Acids Research. 27: 3685-9. PMID 10471737 DOI: 10.1093/Nar/27.18.3685  0.736
1999 Sidow A, Bulotsky MS, Kerrebrock AW, Birren BW, Altshuler D, Jaenisch R, Johnson KR, Lander ES. A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant. Nature Genetics. 23: 104-7. PMID 10471509 DOI: 10.1038/12709  0.332
1999 Csankovszki G, Panning B, Bates B, Pehrson JR, Jaenisch R. Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation. Nature Genetics. 22: 323-4. PMID 10431231 DOI: 10.1038/11887  0.686
1999 Donovan MJ, Natoli TA, Sainio K, Amstutz A, Jaenisch R, Sariola H, Kreidberg JA. Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud. Developmental Genetics. 24: 252-62. PMID 10322633 DOI: 10.1002/(Sici)1520-6408(1999)24:3/4<252::Aid-Dvg8>3.0.Co;2-K  0.679
1999 Bates B, Rios M, Trumpp A, Chen C, Fan G, Bishop JM, Jaenisch R. Neurotrophin-3 is required for proper cerebellar development. Nature Neuroscience. 2: 115-7. PMID 10195193 DOI: 10.1038/5669  0.459
1999 Fan G, Jaenisch R, Kucera J. A role for p75 receptor in neurotrophin-3 functioning during the development of limb proprioception. Neuroscience. 90: 259-68. PMID 10188952 DOI: 10.1016/S0306-4522(98)00432-1  0.494
1998 Chen RZ, Pettersson U, Beard C, Jackson-Grusby L, Jaenisch R. DNA hypomethylation leads to elevated mutation rates. Nature. 395: 89-93. PMID 9738504 DOI: 10.1038/25779  0.75
1998 Jaenisch R, Beard C, Lee J, Marahrens Y, Panning B. Mammalian X chromosome inactivation. Novartis Foundation Symposium. 214: 200-9; discussion 20. PMID 9601019 DOI: 10.1002/9780470515501.Ch12  0.753
1998 Panning B, Jaenisch R. RNA and the epigenetic regulation of X chromosome inactivation. Cell. 93: 305-8. PMID 9590161 DOI: 10.1016/S0092-8674(00)81155-1  0.706
1998 Hormuzdi SG, Penttinen R, Jaenisch R, Bornstein P. A gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene. Molecular and Cellular Biology. 18: 3368-75. PMID 9584177 DOI: 10.1128/Mcb.18.6.3368  0.386
1998 Warnecke PM, Biniszkiewicz D, Jaenisch R, Frommer M, Clark SJ. Sequence-specific methylation of the mouse H19 gene in embryonic cells deficient in the Dnmt-1 gene. Developmental Genetics. 22: 111-21. PMID 9581283 DOI: 10.1002/(Sici)1520-6408(1998)22:2<111::Aid-Dvg1>3.0.Co;2-9  0.389
1998 Kucera J, Fan G, Walro J, Copray S, Tessarollo L, Jaenisch R. Neurotrophin-3 and trkC in muscle are non-essential for the development of mouse muscle spindles. Neuroreport. 9: 905-9. PMID 9579688 DOI: 10.1097/00001756-199803300-00026  0.457
1998 Marahrens Y, Loring J, Jaenisch R. Role of the Xist gene in X chromosome choosing. Cell. 92: 657-64. PMID 9506520 DOI: 10.1016/S0092-8674(00)81133-2  0.31
1998 You Y, Bersgtram R, Klemm M, Nelson H, Jaenisch R, Schimenti J. Utility of C57BL/6J x 129/SvJae embryonic stem cells for generating chromosomal deletions: tolerance to gamma radiation and microsatellite polymorphism. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 232-4. PMID 9501308 DOI: 10.1007/S003359900731  0.354
1998 Aladjem MI, Spike BT, Rodewald LW, Hope TJ, Klemm M, Jaenisch R, Wahl GM. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Current Biology : Cb. 8: 145-55. PMID 9443911 DOI: 10.1016/S0960-9822(98)70061-2  0.4
1998 MOORE A, SCHEDL A, McINNES L, KREIDBERG J, JAENISCH R, HASTIE N. New Wilms' tumour suppressor gene (WT1) functions revealed by YAC transgenic analysis Genetical Research. 72: 59-72. DOI: 10.1017/S001667239834330X  0.579
1997 Pradhan S, Talbot D, Sha M, Benner J, Hornstra L, Li E, Jaenisch R, Roberts RJ. Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase. Nucleic Acids Research. 25: 4666-73. PMID 9358180 DOI: 10.1093/Nar/25.22.4666  0.306
1997 Sidow A, Bulotsky MS, Kerrebrock AW, Bronson RT, Daly MJ, Reeve MP, Hawkins TL, Birren BW, Jaenisch R, Lander ES. Serrate2 is disrupted in the mouse limb-development mutant syndactylism. Nature. 389: 722-5. PMID 9338782 DOI: 10.1038/39587  0.341
1997 Sabapathy K, Klemm M, Jaenisch R, Wagner EF. Regulation of ES cell differentiation by functional and conformational modulation of p53. The Embo Journal. 16: 6217-29. PMID 9321401 DOI: 10.1093/Emboj/16.20.6217  0.482
1997 Panning B, Dausman J, Jaenisch R. X chromosome inactivation is mediated by Xist RNA stabilization. Cell. 90: 907-16. PMID 9298902 DOI: 10.1016/S0092-8674(00)80355-4  0.719
1997 Tucker KL, Wang Y, Dausman J, Jaenisch R. A transgenic mouse strain expressing four drug-selectable marker genes. Nucleic Acids Research. 25: 3745-6. PMID 9278500 DOI: 10.1093/Nar/25.18.3745  0.324
1997 Di Fruscio M, Weiher H, Vanderhyden BC, Imai T, Shiomi T, Hori TA, Jaenisch R, Gray DA. Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest. Molecular and Cellular Biology. 17: 4080-6. PMID 9199343 DOI: 10.1128/Mcb.17.7.4080  0.376
1997 DiPersio CM, Hodivala-Dilke KM, Jaenisch R, Kreidberg JA, Hynes RO. alpha3beta1 Integrin is required for normal development of the epidermal basement membrane. The Journal of Cell Biology. 137: 729-42. PMID 9151677 DOI: 10.1083/Jcb.137.3.729  0.593
1997 Lee JT, Jaenisch R. The (epi)genetic control of mammalian X-chromosome inactivation. Current Opinion in Genetics & Development. 7: 274-80. PMID 9115428 DOI: 10.1016/S0959-437X(97)80138-4  0.515
1997 Jackson-Grusby L, Laird PW, Magge SN, Moeller BJ, Jaenisch R. Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 94: 4681-5. PMID 9114051 DOI: 10.1073/Pnas.94.9.4681  0.798
1997 Lee JT, Jaenisch R. Long-range cis effects of ectopic X-inactivation centres on a mouse autosome. Nature. 386: 275-9. PMID 9069285 DOI: 10.1038/386275A0  0.529
1997 You Y, Bergstrom R, Klemm M, Lederman B, Nelson H, Ticknor C, Jaenisch R, Schimenti J. Chromosomal deletion complexes in mice by radiation of embryonic stem cells. Nature Genetics. 15: 285-8. PMID 9054943 DOI: 10.1038/Ng0397-285  0.363
1997 Marahrens Y, Panning B, Dausman J, Strauss W, Jaenisch R. Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes & Development. 11: 156-66. PMID 9009199 DOI: 10.1101/Gad.11.2.156  0.712
1997 Iruela-Arispe ML, Vernon RB, Wu H, Jaenisch R, Sage EH. Type I collagen-deficient Mov-13 mice do not retain SPARC in the extracellular matrix: implications for fibroblast function. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 207: 171-83. PMID 8906420 DOI: 10.1002/(Sici)1097-0177(199610)207:2<171::Aid-Aja5>3.0.Co;2-E  0.311
1996 Jackson-Grusby L, Jaenisch R. Experimental manipulation of genomic methylation. Seminars in Cancer Biology. 7: 261-8. PMID 9110403 DOI: 10.1006/Scbi.1996.0034  0.732
1996 Lee JT, Jaenisch R. A method for high efficiency YAC lipofection into murine embryonic stem cells. Nucleic Acids Research. 24: 5054-5. PMID 9016681 DOI: 10.1093/Nar/24.24.5054  0.595
1996 Laird PW, Jaenisch R. The role of DNA methylation in cancer genetics and epigenetics Annual Review of Genetics. 30: 441-464. PMID 8982461 DOI: 10.1146/Annurev.Genet.30.1.441  0.659
1996 Kreidberg JA, Donovan MJ, Goldstein SL, Rennke H, Shepherd K, Jones RC, Jaenisch R. Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis. Development (Cambridge, England). 122: 3537-47. PMID 8951069  0.573
1996 Tucker KL, Talbot D, Lee MA, Leonhardt H, Jaenisch R. Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene Proceedings of the National Academy of Sciences of the United States of America. 93: 12920-12925. PMID 8917520 DOI: 10.1073/Pnas.93.23.12920  0.45
1996 Chun J, Jaenisch R. Clonal cell lines produced by infection of neocortical neuroblasts using multiple oncogenes transduced by retroviruses Molecular and Cellular Neurosciences. 7: 304-321. PMID 8793865 DOI: 10.1006/Mcne.1996.0023  0.566
1996 Panning B, Jaenisch R. DNA hypomethylation can activate Xist expression and silence X-linked genes. Genes & Development. 10: 1991-2002. PMID 8769643 DOI: 10.1101/Gad.10.16.1991  0.749
1996 Lee JT, Strauss WM, Dausman JA, Jaenisch R. A 450 kb transgene displays properties of the mammalian X-inactivation center. Cell. 86: 83-94. PMID 8689690 DOI: 10.1016/S0092-8674(00)80079-3  0.577
1996 Gardner H, Kreidberg J, Koteliansky V, Jaenisch R. Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion. Developmental Biology. 175: 301-13. PMID 8626034 DOI: 10.1006/Dbio.1996.0116  0.638
1996 Tucker KL, Beard C, Dausmann J, Jackson-Grusby L, Laird PW, Lei H, Li E, Jaenisch R. Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. Genes & Development. 10: 1008-20. PMID 8608936 DOI: 10.1101/Gad.10.8.1008  0.824
1995 Kucera J, Fan G, Jaenisch R, Linnarsson S, Ernfors P. Dependence of developing group Ia afferents on neurotrophin-3. The Journal of Comparative Neurology. 363: 307-20. PMID 8642077 DOI: 10.1002/Cne.903630211  0.476
1995 Matzuk MM, Kumar TR, Vassalli A, Bickenbach JR, Roop DR, Jaenisch R, Bradley A. Functional analysis of activins during mammalian development. Nature. 374: 354-6. PMID 7885473 DOI: 10.1038/374354A0  0.716
1995 Wu H, Liu X, Jaenisch R, Lodish HF. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell. 83: 59-67. PMID 7553874 DOI: 10.1016/0092-8674(95)90234-1  0.303
1995 Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Jung WE, Li E, Weinberg RA, Jaenisch R. Suppression of intestinal neoplasia by DNA hypomethylation. Cell. 81: 197-205. PMID 7537636 DOI: 10.1016/0092-8674(95)90329-1  0.786
1994 Fässler R, Schnegelsberg PN, Dausman J, Shinya T, Muragaki Y, McCarthy MT, Olsen BR, Jaenisch R. Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 5070-4. PMID 8197187 DOI: 10.1073/Pnas.91.11.5070  0.509
1994 Vassalli A, Matzuk MM, Gardner HA, Lee KF, Jaenisch R. Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction. Genes & Development. 8: 414-27. PMID 8125256 DOI: 10.1101/Gad.8.4.414  0.729
1994 Li E, Beard C, Forster AC, Bestor TH, Jaenisch R. DNA methylation, genomic imprinting, and mammalian development. Cold Spring Harbor Symposia On Quantitative Biology. 58: 297-305. PMID 7956042 DOI: 10.1101/Sqb.1993.058.01.035  0.314
1994 Laird PW, Jaenisch R. DNA methylation and cancer Human Molecular Genetics. 3: 1487-1495. PMID 7849743 DOI: 10.1093/Hmg/3.Suppl_1.1487  0.677
1993 Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, Jaenisch R. WT-1 is required for early kidney development. Cell. 74: 679-91. PMID 8395349 DOI: 10.1016/0092-8674(93)90515-R  0.649
1993 Li E, Sucov HM, Lee KF, Evans RM, Jaenisch R. Normal development and growth of mice carrying a targeted disruption of the α1 retinoic acid receptor gene Proceedings of the National Academy of Sciences of the United States of America. 90: 1590-1594. PMID 7679509 DOI: 10.1073/Pnas.90.4.1590  0.375
1993 Brenner DA, Veloz L, Jaenisch R, Alcorn JM. Stimulation of the collagen α1(I) endogenous gene and transgene in carbon tetrachloride–induced hepatic fibrosis Hepatology. 17: 287-292. DOI: 10.1002/Hep.1840170220  0.318
1992 Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 69: 915-26. PMID 1606615 DOI: 10.1016/0092-8674(92)90611-F  0.424
1992 Mombaerts P, Clarke AR, Rudnicki MA, Iacomini J, Itohara S, Lafaille JJ, Wang L, Ichikawa Y, Jaenisch R, Hooper ML. Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages. Nature. 360: 225-31. PMID 1359428 DOI: 10.1038/360225A0  0.577
1992 Lee KF, Li E, Huber LJ, Landis SC, Sharpe AH, Chao MV, Jaenisch R. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell. 69: 737-49. PMID 1317267 DOI: 10.1016/0092-8674(92)90286-L  0.327
1992 Wu H, Fässler R, Schnieke A, Barker D, Lee KH, Chapman V, Francke U, Jaenisch R. An X-linked human collagen transgene escapes X inactivation in a subset of cells. Development (Cambridge, England). 116: 687-95. PMID 1289060  0.545
1991 Chun JJ, Schatz DG, Oettinger MA, Jaenisch R, Baltimore D. The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Cell. 64: 189-200. PMID 1986864 DOI: 10.1016/0092-8674(91)90220-S  0.518
1991 Laird PW, Zijderveld A, Linders K, Rudnicki MA, Jaenisch R, Berns A. Simplified mammalian DNA isolation procedure Nucleic Acids Research. 19: 4293. PMID 1870982 DOI: 10.1093/Nar/19.15.4293  0.619
1991 Petersen R, Sobel S, Wang CT, Jaenisch R, Barklis E. Cellular transcripts encoded at a locus which permits retrovirus expression in mouse embryonic cells. Gene. 101: 177-83. PMID 1711497 DOI: 10.1016/0378-1119(91)90409-5  0.303
1990 Zijlstra M, Li E, Sajjadi F, Subramani S, Jaenisch R. Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells. Nature. 342: 435-8. PMID 2685607 DOI: 10.1038/342435A0  0.337
1990 Harbers K, Francke U, Soriano P, Jaenisch R, Müller U. Structure and chromosomal mapping of a highly polymorphic repetitive DNA sequence from the pseudoautosomal region of the mouse sex chromosomes. Cytogenetics and Cell Genetics. 53: 129-33. PMID 1973377 DOI: 10.1159/000132912  0.554
1990 Weiher H, Noda T, Gray DA, Sharpe AH, Jaenisch R. Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome Cell. 62: 425-434. PMID 1696177 DOI: 10.1016/0092-8674(90)90008-3  0.324
1989 Stuhlmann H, Jaenisch R, Mulligan RC. Transfer of a mutant dihydrofolate reductase gene into pre- and postimplantation mouse embryos by a replication-competent retrovirus vector. Journal of Virology. 63: 4857-65. PMID 2795720 DOI: 10.1128/Jvi.63.11.4857-4865.1989  0.323
1989 Compere SJ, Baldacci P, Sharpe AH, Thompson T, Land H, Jaenisch R. The ras and myc oncogenes cooperate in tumor induction in many tissues when introduced into midgestation mouse embryos by retroviral vectors Proceedings of the National Academy of Sciences of the United States of America. 86: 2224-2228. PMID 2648394 DOI: 10.1073/Pnas.86.7.2224  0.313
1987 Weiher H, Barklis E, Ostertag W, Jaenisch R. Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells. Journal of Virology. 61: 2742-6. PMID 3612950 DOI: 10.1128/Jvi.61.9.2742-2746.1987  0.392
1987 Stacey A, Mulligan R, Jaenisch R. Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells. Journal of Virology. 61: 2549-54. PMID 3599181 DOI: 10.1128/Jvi.61.8.2549-2554.1987  0.318
1987 Soriano P, Keitges EA, Schorderet DF, Harbers K, Gartler SM, Jaenisch R. High rate of recombination and double crossovers in the mouse pseudoautosomal region during male meiosis. Proceedings of the National Academy of Sciences of the United States of America. 84: 7218-20. PMID 3478692 DOI: 10.1073/Pnas.84.20.7218  0.566
1987 Soriano P, Gridley T, Jaenisch R. Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death. Genes & Development. 1: 366-75. PMID 2824282 DOI: 10.1101/Gad.1.4.366  0.587
1987 Gridley T, Soriano P, Jaenisch R. Insertional mutagenesis in mice Trends in Genetics. 3: 162-166. DOI: 10.1016/0168-9525(87)90218-6  0.577
1986 Barklis E, Mulligan RC, Jaenisch R. Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells. Cell. 47: 391-9. PMID 3768959 DOI: 10.1016/0092-8674(86)90596-9  0.383
1986 Harbers K, Soriano P, Müller U, Jaenisch R. High frequency of unequal recombination in pseudoautosomal region shown by proviral insertion in transgenic mouse. Nature. 324: 682-5. PMID 3025741 DOI: 10.1038/324682A0  0.569
1986 Soriano P, Cone RD, Mulligan RC, Jaenisch R. Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses. Science (New York, N.Y.). 234: 1409-13. PMID 3024318 DOI: 10.1126/Science.3024318  0.602
1986 Soriano P, Jaenisch R. Retroviruses as probes for mammalian development: allocation of cells to the somatic and germ cell lineages. Cell. 46: 19-29. PMID 3013418 DOI: 10.1016/0092-8674(86)90856-1  0.61
1985 Stuhlmann H, Cone R, Mulligan RC, Jaenisch R. Introduction of a selectable gene into different animal tissue by a retrovirus recombinant vector. Proceedings of the National Academy of Sciences of the United States of America. 81: 7151-5. PMID 6095271 DOI: 10.1073/Pnas.81.22.7151  0.364
1985 Jähner D, Haase K, Mulligan R, Jaenisch R. Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection. Proceedings of the National Academy of Sciences of the United States of America. 82: 6927-31. PMID 2413448 DOI: 10.1073/Pnas.82.20.6927  0.378
1983 Jaenisch R, Harbers K, Jähner D, Stewart C, Stuhlmann H. DNA methylation, retroviruses, and embryogenesis. Journal of Cellular Biochemistry. 20: 331-6. PMID 7183678 DOI: 10.1002/Jcb.240200403  0.428
1983 Jaenisch R, Harbers K, Jähner D, Stewart C, Stuhlmann H. Expression of retroviruses during early mouse embryogenesis. Haematology and Blood Transfusion. 28: 270-4. PMID 6862303 DOI: 10.1007/978-3-642-68761-7_50  0.355
1983 Stewart C, Harbers K, Jähner D, Jaenisch R. X chromosome-linked transmission and expression of retroviral genomes microinjected into mouse zygotes. Science (New York, N.Y.). 221: 760-2. PMID 6683871 DOI: 10.1126/Science.6683871  0.333
1983 Jähner D, Stewart CL, Stuhlmann H, Harbers K, Jaenisch R. Retroviruses and embryogenesis: de novo methylation activity involved in gene expression. Cold Spring Harbor Symposia On Quantitative Biology. 611-9. PMID 6574867 DOI: 10.1101/Sqb.1983.047.01.072  0.341
1982 Stewart CL, Stuhlmann H, Jähner D, Jaenisch R. De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 4098-102. PMID 6955793 DOI: 10.1073/Pnas.79.13.4098  0.398
1982 Jähner D, Stuhlmann H, Stewart CL, Harbers K, Löhler J, Simon I, Jaenisch R. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature. 298: 623-8. PMID 6285203 DOI: 10.1038/298623A0  0.353
1980 Doehmer J, Breindl M, Willecke K, Jaenisch R. Genetic transmission of Moloney leukemia virus: mapping of the chromosomal integration site. Haematology and Blood Transfusion. 23: 561-8. PMID 544367 DOI: 10.1007/978-3-642-67057-2_72  0.323
1979 Breindl M, Doehmer J, Willecke K, Dausman J, Jaenisch R. Germ line integration of Moloney leukemia virus: identification of the chromosomal integration site. Proceedings of the National Academy of Sciences of the United States of America. 76: 1938-42. PMID 287034 DOI: 10.1073/Pnas.76.4.1938  0.324
1974 Jaenisch R, Mintz B. Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA. Proceedings of the National Academy of Sciences of the United States of America. 71: 1250-4. PMID 4364530 DOI: 10.1073/Pnas.71.4.1250  0.518
1973 Jaenisch R, Levine AJ. DNA replication of SV40-infected cells. VII. Formation of SV40 catenated and circular dimers. Journal of Molecular Biology. 73: 199-212. PMID 4347738  0.393
1972 Jaenisch R, Levine AJ. DNA replication in SV40-infected cells. VI. The effect of cycloheximide on the formation of SV40 oligomeric DNA. Virology. 48: 373-9. PMID 4337027  0.382
1972 Dubbs DR, Kit S, Jaenisch R, Levine AJ. Isolation of simian virus 40 recombinants from cells infected with oligomeric forms of simian virus 40 deoxyribonucleic acid. Journal of Virology. 9: 717-9. PMID 4336567 DOI: 10.1128/Jvi.9.4.717-719.1972  0.458
1971 Jaenisch R, Levine AJ. Infection of primary African green monkey cells with SV40 monomeric and dimeric DNA. Journal of Molecular Biology. 61: 735-8. PMID 4332233  0.382
1970 Jaenisch R, Jacob E, Hofschneider PH. Replication of the small coliphage M13: evidence for long-living M13 specific messenger RNA. Nature. 227: 59-60. PMID 5422625 DOI: 10.1038/227059A0  0.447
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