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Gene A. Homandberg - Publications

Affiliations: 
Rush University, Chicago, IL, United States 
Area:
Biochemistry
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Ding L, Guo D, Homandberg GA, Buckwalter JA, Martin JA. A single blunt impact on cartilage promotes fibronectin fragmentation and upregulates cartilage degrading stromelysin-1/matrix metalloproteinase-3 in a bovine ex vivo model. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 811-8. PMID 24610678 DOI: 10.1002/Jor.22610  0.398
2009 Ding L, Guo D, Homandberg GA. Fibronectin fragments mediate matrix metalloproteinase upregulation and cartilage damage through proline rich tyrosine kinase 2, c-src, NF-κB and protein kinase Cδ Osteoarthritis and Cartilage. 17: 1385-1392. PMID 19409294 DOI: 10.1016/j.joca.2009.03.024  0.335
2009 Guo D, Ding L, Homandberg GA. Telopeptides of type II collagen upregulate proteinases and damage cartilage but are less effective than highly active fibronectin fragments Inflammation Research. 58: 161-169. PMID 19190855 DOI: 10.1007/s00011-009-8090-5  0.375
2008 Ding L, Guo D, Homandberg GA. The cartilage chondrolytic mechanism of fibronectin fragments involves MAP kinases: comparison of three fragments and native fibronectin Osteoarthritis and Cartilage. 16: 1253-1262. PMID 18396067 DOI: 10.1016/j.joca.2008.02.015  0.358
2007 Homandberg GA, Ding L, Guo D. Extracellular matrix fragments as regulators of cartilage metabolism in health and disease Current Rheumatology Reviews. 3: 183-196. DOI: 10.2174/157339707781387590  0.304
2006 Homandberg GA, Guo D, Ray LM, Ding L. Mixtures of glucosamine and chondroitin sulfate reverse fibronectin fragment mediated damage to cartilage more effectively than either agent alone. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 14: 793-806. PMID 16581272 DOI: 10.1016/j.joca.2006.02.003  0.33
2006 Homandberg GA. Mechanisms of beneficial effects of high molecular weight hyaluronan on cultured cartilage tissue Current Rheumatology Reviews. 2: 23-30. DOI: 10.2174/157339706775696973  0.305
2004 Homandberg GA, Ummadi V, Kang H. Hyaluronan enhances cartilage repair through low grade tissue remodeling involving cytokines and matrix metalloproteinases Inflammation Research. 53: 534-543. PMID 15597148 DOI: 10.1007/s00011-004-1292-y  0.438
2004 Pichika R, Homandberg GA. Fibronectin fragments elevate nitric oxide (NO) and inducible NO synthetase (iNOS) levels in bovine cartilage and iNOS inhibitors block fibronectin fragment mediated damage and promote repair Inflammation Research. 53: 405-412. PMID 15316672  0.418
2004 Homandberg GA, Ummadi V, Kang H. The role of insulin-like growth factor-I in hyaluronan mediated repair of cultured cartilage explants Inflammation Research. 53: 396-404. PMID 15316671  0.336
2003 Dang Y, Cole AA, Homandberg GA. Comparison of the catabolic effects of fibronectin fragments in human knee and ankle cartilages. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 11: 538-47. PMID 12814617 DOI: 10.1016/S1063-4584(03)00085-2  0.331
2003 Homandberg GA, Ummadi V, Kang H. High molecular weight hyaluronan promotes repair of IL-1 beta-damaged cartilage explants from both young and old bovines. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 11: 177-86. PMID 12623289 DOI: 10.1016/S1063-4584(02)00371-0  0.338
2003 Williams JM, Zhang J, Kang H, Ummadi V, Homandberg GA. The effects of hyaluronic acid on fibronectin fragment mediated cartilage chondrolysis in skeletally mature rabbits Osteoarthritis and Cartilage. 11: 44-49. PMID 12505486 DOI: 10.1053/joca.2002.0864  0.341
2002 Homandberg GA, Costa V, Ummadi V, Pichika R. Antisense oligonucleotides to the integrin receptor subunit alpha5 decrease fibronectin fragment mediated cartilage chondrolysis Osteoarthritis and Cartilage. 10: 381-393. PMID 12027539 DOI: 10.1053/joca.2002.0524  0.385
2001 Homandberg GA, Kang Y, Zhang J, Cole AA, Williams JM. A single injection of fibronectin fragments into rabbit knee joints enhances catabolism in the articular cartilage followed by reparative responses but also induces systemic effects in the non-injected knee joints. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 9: 673-83. PMID 11795986 DOI: 10.1053/Joca.2001.0419  0.327
2001 Homandberg GA. Cartilage damage by matrix degradation products: Fibronectin fragments Clinical Orthopaedics and Related Research. PMID 11603694  0.33
1999 Kang Y, Eger W, Koepp H, Williams JM, Kuettner KE, Homandberg GA. Hyaluronan suppresses fibronectin fragment-mediated damage to human cartilage explant cultures by enhancing proteoglycan synthesis Journal of Orthopaedic Research. 17: 858-869. PMID 10632453  0.455
1999 Homandberg GA. Potential regulation of cartilage metabolism in osteoarthritis by fibronectin fragments Frontiers in Bioscience : a Journal and Virtual Library. 4. PMID 10525477  0.371
1999 Koepp HE, Sampath KT, Kuettner KE, Homandberg GA. Osteogenic protein-1 (OP-1) blocks cartilage damage caused by fibronectin fragments and promotes repair by enhancing proteoglycan synthesis. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 48: 199-204. PMID 10344470 DOI: 10.1007/s000110050446  0.309
1998 Homandberg GA, Wen C, Hui F. Cartilage damaging activities of fibronectin fragments derived from cartilage and synovial fluid Osteoarthritis and Cartilage. 6: 231-244. PMID 9876392 DOI: 10.1053/joca.1998.0116  0.358
1998 Kang Y, Koepp H, Cole AA, Kuettner KE, Homandberg GA. Cultured human ankle and knee cartilage differ in susceptibility to damage mediated by fibronectin fragments. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 16: 551-6. PMID 9820277 DOI: 10.1002/Jor.1100160505  0.398
1997 Homandberg GA. Cartilage chondrolysis by fibronectin fragments causes cleavage of aggrecan at the same site as found in osteoarthritic cartilage Osteoarthritis and Cartilage. 5: 450-453. PMID 9536293  0.48
1997 Homandberg GA, Hui F, Wen C, Kuettner KE, Williams JM. Hyaluronic acid suppresses fibronectin fragment mediated cartilage chondrolysis: I. In vitro Osteoarthritis and Cartilage. 5: 309-319. PMID 9497938 DOI: 10.1016/S1063-4584(97)80035-0  0.467
1997 Homandberg GA, Wen C, Hui F. Agents that block fibronectin fragment-mediated cartilage damage also promote repair Inflammation Research. 46: 467-471. PMID 9427068 DOI: 10.1007/s000110050226  0.303
1997 Williams JM, Plaza V, Hui F, Wen C, Kuettner KE, Homandberg GA. Hyaluronic acid suppresses fibronectin fragment mediated cartilage chondrolysis: II. In vivo Osteoarthritis and Cartilage. 5: 235-240. PMID 9404468 DOI: 10.1016/S1063-4584(97)80019-2  0.409
1997 Homandberg GA, Hui F, Wen C, Purple C, Bewsey K, Koepp H, Huch K, Harris A. Fibronectin-fragment-induced cartilage chondrolysis is associated with release of catabolic cytokines Biochemical Journal. 321: 751-757. PMID 9032463  0.446
1996 Homandberg GA, Hui F, Wen C. Fibronectin fragment mediated cartilage chondrolysis. II. Reparative effects of anti-oxidants Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1317: 143-148. PMID 8950200 DOI: 10.1016/S0925-4439(96)00045-2  0.458
1996 Homandberg GA, Hui F, Wen C. Fibronectin fragment mediated cartilage chondrolysis. I. Suppression by anti-oxidants Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1317: 134-142. PMID 8950199 DOI: 10.1016/S0925-4439(96)00046-4  0.477
1996 Homandberg GA, Hui F. Association of proteoglycan degradation with catabolic cytokine and stromelysin release from cartilage cultured with fibronectin fragments Archives of Biochemistry and Biophysics. 334: 325-331. PMID 8900407 DOI: 10.1006/abbi.1996.0461  0.366
1996 Bewsey KE, Wen C, Purple C, Homandberg GA. Fibronectin fragments induce the expression of stromelysin-1 mRNA and protein in bovine chondrocytes in monolayer culture Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1317: 55-64. PMID 8876627 DOI: 10.1016/0925-4439(96)00037-3  0.421
1994 Homandberg GA, Hui F. High concentrations of fibronectin fragments cause short-term catabolic effects in cartilage tissue while lower concentrations cause continuous anabolic effects Archives of Biochemistry and Biophysics. 311: 213-218. PMID 8203883 DOI: 10.1006/abbi.1994.1229  0.436
1994 Xie DL, Hui F, Meyers R, Homandberg GA. Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysis. Archives of Biochemistry and Biophysics. 311: 205-12. PMID 8203882 DOI: 10.1006/abbi.1994.1228  0.415
1994 Homandberg GA, Hui F. Arg-Gly-Asp-Ser peptide analogs suppress cartilage chondrolytic activities of integrin-binding and nonbinding fibronectin fragments Archives of Biochemistry and Biophysics. 310: 40-48. PMID 8161219 DOI: 10.1006/abbi.1994.1137  0.393
1993 Xie Dl, Homandberg GA. Fibronectin fragments bind to and penetrate cartilage tissue resulting in proteinase expression and cartilage damage Bba - Molecular Basis of Disease. 1182: 189-196. PMID 8357850 DOI: 10.1016/0925-4439(93)90140-V  0.404
1993 Xie D, Hui F, Homandberg GA. Fibronectin fragments alter matrix protein synthesis in cartilage tissue cultured in vitro Archives of Biochemistry and Biophysics. 307: 110-118. PMID 8239647 DOI: 10.1006/abbi.1993.1568  0.466
1993 Homandberg GA, Meyers R, Williams JM. Intraarticular injection of fibronectin fragments causes severe depletion of cartilage proteoglycans in vivo. The Journal of Rheumatology. 20: 1378-82. PMID 8230023  0.464
1992 Homandberg GA, Meyers R, Xie DL. Fibronectin fragments cause chondrolysis of bovine articular cartilage slices in culture. The Journal of Biological Chemistry. 267: 3597-604. PMID 1740411  0.312
1992 Xie DL, Meyers R, Homandberg GA. Fibronectin fragments in osteoarthritic synovial fluid. The Journal of Rheumatology. 19: 1448-52. PMID 1433014  0.358
1992 Homandberg GA, Meyers R, Aydelotte M, Tripier D, Kuettner KE. Isolation and characterization of an abundant elastase inhibitor from NaCl extracts of bovine nasal septa and articular cartilage. Connective Tissue Research. 28: 289-305. PMID 1304443 DOI: 10.3109/03008209209016821  0.341
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