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Michaela Jansen - Publications

Affiliations: 
 
Area:
ion channel
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59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Do HQ, Pirayesh E, Ferreira G, Pandhare A, Gallardo ZR, Jansen M. A bupropion modulatory site in the Gloeobacter violaceus ligand-gated ion channel. Biophysical Journal. PMID 38678367 DOI: 10.1016/j.bpj.2024.04.027  0.336
2023 Pirayesh E, Do HQ, Ferreira G, Pandhare A, Gallardo ZR, Jansen M. Identification of a binding site for bupropion in ligand-gated ion channel. Biorxiv : the Preprint Server For Biology. PMID 37873398 DOI: 10.1101/2023.10.09.561596  0.313
2023 Do HQ, Jansen M. Binding motif for RIC-3 chaperon protein in serotonin type 3A receptors. The Journal of General Physiology. 155. PMID 37026993 DOI: 10.1085/jgp.202213305  0.308
2020 Shepherd J, Onyejegbu D, Stuebler A, Gallardo Z, Hornback C, Jansen M. Identification of the Binding Site of Bupropion on Serotonin Type 3A Receptors Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3174  0.333
2019 Stuebler AG, Jansen M. Bupropion inhibits serotonin type 3AB heteromeric channels at clinically relevant concentrations. Molecular Pharmacology. PMID 31871303 DOI: 10.1124/Mol.119.118349  0.384
2019 Pirayesh E, Stuebler AG, Pandhare A, Jansen M. Delineating the Site of Interaction of the 5-HT Receptor with the Chaperone Protein RIC-3. Biophysical Journal. PMID 31870537 DOI: 10.1016/J.Bpj.2019.11.3380  0.369
2019 Pandhare A, Pirayesh E, Stuebler AG, Jansen M. Triple arginines as molecular determinants for pentameric assembly of the intracellular domain of 5-HT receptors. The Journal of General Physiology. PMID 31409663 DOI: 10.1085/Jgp.201912421  0.437
2019 Pirayesh E, Stuebler AG, Jansen M. In-Vivo and In-Vitro Studies to Identify the Interaction Site of the Intracellular Domain of Serotonin Type 3A (5-HT3A-ICD) and Chaperon Protein RIC-3 Biophysical Journal. 116: 393a. DOI: 10.1016/J.Bpj.2018.11.2125  0.331
2019 Stuebler A, Jansen M. A Comparison between Homomeric and Heteromeric 5-HT3 Receptors in Response to the Antidepressant Bupropion Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2124  0.318
2018 Pandhare A, Stuebler AG, Pirayesh E, Jansen M. A modified clear-native polyacrylamide gel electrophoresis technique to investigate the oligomeric state of MBP-5-HT-intracellular domain chimeras. Protein Expression and Purification. 153: 45-52. PMID 30130580 DOI: 10.1016/J.Pep.2018.08.010  0.347
2018 Pandhare A, Ahmed AF, Littlejohn JV, Jansen M. Highly Pure Soluble Chimeras of the Intracellular Domain of Anionic Pentameric Ligand-Gated Ion Channels Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1710  0.337
2018 Pirayesh E, Jansen M. Interaction Sites of Serotonin Type 3A Intracellular Domain (5-HT 3A -ICD) with Chaperon Protein RIC-3 Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1703  0.321
2018 Stuebler A, Jansen M. Effects of 5-HT 3A Intracellular Domain Modifications on Oligomerization Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1702  0.317
2017 Date SS, Fiori MC, Altenberg GA, Jansen M. Expression in Sf9 insect cells, purification and functional reconstitution of the human proton-coupled folate transporter (PCFT, SLC46A1). Plos One. 12: e0177572. PMID 28493963 DOI: 10.1371/Journal.Pone.0177572  0.317
2017 Ahmadi M, Pandhare A, Jansen M. Development of a Pentameric, Non-Chimeric 5-HT3A Receptor Intracellular Domain Construct Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2993  0.345
2017 Pandhare A, Jansen M. Characterizing the Intrinsic Assembly Behavior of the 5-HT3A Receptor Intracellular Domain Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2992  0.383
2017 Stuebler A, Artigas P, Jansen M. The Intracellular Domain of Pentameric Ligand-Gated Ion Channels and its Effect on Receptor Conductance in GLIC Chimeras Biophysical Journal. 112: 553. DOI: 10.1016/J.Bpj.2016.11.2983  0.407
2016 Pandhare A, Pappu AS, Wilms H, Blanton MP, Jansen M. The antidepressant bupropion is a negative allosteric modulator of serotonin type 3A receptors. Neuropharmacology. PMID 27671323 DOI: 10.1016/J.Neuropharm.2016.09.021  0.416
2016 Date SS, Chen CC, Chen Y, Jansen M. Experimentally optimized threading structures of the proton-coupled folate transporter. Febs Open Bio. 6: 216-230. PMID 27047750 DOI: 10.1002/2211-5463.12041  0.331
2016 Pandhare A, Grozdanov PN, Jansen M. Pentameric quaternary structure of the intracellular domain of serotonin type 3A receptors. Scientific Reports. 6: 23921. PMID 27045630 DOI: 10.1038/Srep23921  0.413
2016 Nishtala SN, Mnatsakanyan N, Pandhare A, Leung C, Jansen M. Direct interaction of the resistance to inhibitors of cholinesterase (RIC-3) protein with the serotonin receptor type 3A (5-HT3A ) intracellular domain. Journal of Neurochemistry. PMID 26875553 DOI: 10.1111/Jnc.13578  0.421
2016 Date S, Fiori M, Sok N, Urbatsch I, Jansen M. Expression, Purification and Functional Characterization of Human Proton-Coupled Folate Transporter (SLC46A1) Biophysical Journal. 110: 138a. DOI: 10.1016/J.Bpj.2015.11.786  0.312
2016 Jenkins K, Pandhare A, Delin LJ, Jansen M. Expression and Purification of the Intracellular Domain of a Cationic Pentameric Ligand-Gated Ion Channel Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.3217  0.403
2016 Delin LJ, Pandhare A, Jenkins K, Jansen M. A Soluble GABAAρ1 Intracellular Domain Chimera for Structural Studies Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2441  0.414
2016 Pandhare A, Grozdanov PN, Jansen M. Pentameric Structure of the Soluble Intracellular Domain of 5-HT3A Receptors Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2431  0.455
2016 Pirayesh E, Leung F, Pandhare A, Jansen M. Characterization of the Interaction of the Intracellular Domain of 5-HT3A Receptors with the Chaperone Protein RIC-3 Biophysical Journal. 110: 453a. DOI: 10.1016/J.Bpj.2015.11.2430  0.438
2016 Jansen M. Insights into Intracellular Domains of Pentameric Ligand-Gated Ion Channels Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.117  0.344
2015 Mnatsakanyan N, Nishtala SN, Pandhare A, Fiori MC, Goyal R, Pauwels JE, Navetta AF, Ahrorov A, Jansen M. Functional Chimeras of GLIC Obtained by Adding the Intracellular Domain of Anion- and Cation-Conducting Cys-Loop Receptors. Biochemistry. 54: 2670-82. PMID 25861708 DOI: 10.1021/Acs.Biochem.5B00203  0.426
2015 Thompson JM, Pappu A, Pandhare A, Jansen M. Complex Modulation of the GABAA α1β2γ2 Receptor Function by Bupropion Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2366  0.383
2015 Pandhare A, Gagnon D, Wilms H, Blanton MP, Jansen M. Interaction of Bupropion with 5-HT3A Receptors Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2364  0.399
2015 Date S, Chen CC, Chen Y, Jansen M. The Human Proton-Coupled Folate Transporter: Determination of Conformation and Identification of the Folate-Binding Pocket Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1682  0.346
2014 Date S, Jansen M. Experimentally Defined Structural Model of the Human Proton-Coupled Folate Transporter Biophysical Journal. 106: 368a. DOI: 10.1016/J.Bpj.2013.11.2087  0.323
2014 Nishtala SN, Mnatsakanyan N, Jansen M. Direct Interaction of RIC-3 with the Intracellular Domain of Eukaryotic Cationic Pentameric Ligand-Gated Ion Channels Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.1954  0.408
2014 Pandhare A, Riela S, Jansen M, Blanton MP. Neuronal Nicotinic Acetylcholine Receptors: The Development of Methods for Producing Affinity-Purified and Lipid-Reconstituted Receptors that Retain Functionality Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.1943  0.35
2013 Duddempudi PK, Goyal R, Date SS, Jansen M. Delineating the extracellular water-accessible surface of the proton-coupled folate transporter. Plos One. 8: e78301. PMID 24205192 DOI: 10.1371/Journal.Pone.0078301  0.312
2013 Duddempudi PK, Nakashe P, Blanton MP, Jansen M. The monomeric state of the proton-coupled folate transporter represents the functional unit in the plasma membrane. The Febs Journal. 280: 2900-15. PMID 23601781 DOI: 10.1111/Febs.12293  0.34
2013 Mnatsakanyan N, Jansen M. Experimental determination of the vertical alignment between the second and third transmembrane segments of muscle nicotinic acetylcholine receptors. Journal of Neurochemistry. 125: 843-54. PMID 23565737 DOI: 10.1111/Jnc.12260  0.435
2013 Labriola JM, Pandhare A, Jansen M, Blanton MP, Corringer PJ, Baenziger JE. Structural sensitivity of a prokaryotic pentameric ligand-gated ion channel to its membrane environment. The Journal of Biological Chemistry. 288: 11294-303. PMID 23463505 DOI: 10.1074/Jbc.M113.458133  0.357
2013 Mnatsakanyan N, Nishtala SN, Jansen M. Analysis of Secondary Structure Elements in the Intracellular Domain of GLIC Chimeras with ICD from Eukaryotic Cys-Loop Receptors Biophysical Journal. 104: 6-6. DOI: 10.1016/J.Bpj.2012.11.3515  0.437
2012 Pandhare A, Hamouda AK, Staggs B, Aggarwal S, Duddempudi PK, Lever JR, Lapinsky DJ, Jansen M, Cohen JB, Blanton MP. Bupropion binds to two sites in the Torpedo nicotinic acetylcholine receptor transmembrane domain: a photoaffinity labeling study with the bupropion analogue [(125)I]-SADU-3-72. Biochemistry. 51: 2425-35. PMID 22394379 DOI: 10.1021/Bi300101R  0.404
2012 Pandhare A, Jansen M, Blanton MP. Injection of Affinity-Purified Ligand-Gated Ion Channels into Xenopus Laevis Oocytes for Functional Studies using Electrophysiology Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.662  0.371
2012 Pandhare A, Hamouda AK, Staggs B, Duddempudi PK, Lever JR, Cohen JB, Lapinsky DJ, Jansen M, Blanton MP. Bupropion Binds in the Middle (M2-9) of the Torpedo Nicotinic Acetylcholine Receptor Ion Channel Biophysical Journal. 102: 118a. DOI: 10.1016/J.Bpj.2011.11.661  0.365
2012 Goyal R, Navetta A, Nishtala SN, Salahudeen AA, Pauwels JE, Mnatsakanyan N, Jansen M. Eukaryotic-Prokaryotic Chimeras for Structure-Function Studies of the Intracellular Domain of Cys-Loop Receptors Biophysical Journal. 102: 1-7. DOI: 10.1016/J.Bpj.2011.11.655  0.409
2012 Duddempudi PK, Goyal R, Blanton MP, Jansen M. Identifying the Lipid-Protein Interface of the Proton-Coupled Folate Transporter using Hydrophobic Photoreactive Probes Biophysical Journal. 102: 522a. DOI: 10.1016/J.Bpj.2011.11.2854  0.316
2011 Goyal R, Salahudeen AA, Jansen M. Engineering a prokaryotic Cys-loop receptor with a third functional domain. The Journal of Biological Chemistry. 286: 34635-42. PMID 21844195 DOI: 10.1074/Jbc.M111.269647  0.414
2011 Nakashe P, Jansen M. Analysis of the Oligomeric State of Surface-Localized Proton-Coupled Folate Transporter by Blue Native Polyacrylamide Gel Electrophoresis Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.1556  0.355
2011 Bauman A, Piel M, Höhnemann S, Krauss A, Jansen M, Solbach C, Dannhardt G, Rösch F. Synthesis, labelling and evaluation of hydantoin-substituted indole carboxylic acids as potential ligands for positron emission tomography imaging of the glycine binding site of the N-methyl- d -aspartate receptor Journal of Labelled Compounds and Radiopharmaceuticals. 54: 645-656. DOI: 10.1002/Jlcr.1901  0.305
2010 Brahmamudi G, Langsjoen D, D'Cunha RM, Jansen M. Highly Mobile Channel Lining Transmembrane Segments in Muscle Nicotinic Acetylcholine Receptors Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.702  0.454
2010 Nakashe P, Duddempudi PK, Blanton MP, Jansen M. Structure Function Studies of the Proton Coupled Folate Transporter Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.2757  0.343
2009 Bali M, Jansen M, Akabas MH. GABA-induced intersubunit conformational movement in the GABAA receptor alpha 1M1-beta 2M3 transmembrane subunit interface: experimental basis for homology modeling of an intravenous anesthetic binding site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3083-92. PMID 19279245 DOI: 10.1523/Jneurosci.6090-08.2009  0.703
2009 Wiltfong RE, Jansen M. Probing protein packing surrounding the residues in and flanking the nicotinic acetylcholine receptor M2M3 loop. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1626-35. PMID 19211870 DOI: 10.1523/Jneurosci.4121-08.2009  0.439
2008 Jansen M, Rabe H, Strehle A, Dieler S, Debus F, Dannhardt G, Akabas MH, Lüddens H. Synthesis of GABAA receptor agonists and evaluation of their alpha-subunit selectivity and orientation in the GABA binding site. Journal of Medicinal Chemistry. 51: 4430-48. PMID 18651727 DOI: 10.1021/Jm701562X  0.596
2008 Zhao R, Qiu A, Tsai E, Jansen M, Akabas MH, Goldman ID. The proton-coupled folate transporter: impact on pemetrexed transport and on antifolates activities compared with the reduced folate carrier. Molecular Pharmacology. 74: 854-62. PMID 18524888 DOI: 10.1124/Mol.108.045443  0.593
2008 Jansen M, Bali M, Akabas MH. Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop. The Journal of General Physiology. 131: 137-46. PMID 18227272 DOI: 10.1085/Jgp.200709896  0.713
2007 Qiu A, Min SH, Jansen M, Malhotra U, Tsai E, Cabelof DC, Matherly LH, Zhao R, Akabas MH, Goldman ID. Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction. American Journal of Physiology. Cell Physiology. 293: C1669-78. PMID 17898134 DOI: 10.1152/Ajpcell.00202.2007  0.611
2006 Qiu A, Jansen M, Sakaris A, Min SH, Chattopadhyay S, Tsai E, Sandoval C, Zhao R, Akabas MH, Goldman ID. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell. 127: 917-28. PMID 17129779 DOI: 10.1016/J.Cell.2006.09.041  0.584
2006 Jansen M, Akabas MH. State-dependent cross-linking of the M2 and M3 segments: functional basis for the alignment of GABAA and acetylcholine receptor M3 segments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4492-9. PMID 16641228 DOI: 10.1523/Jneurosci.0224-06.2006  0.647
2005 Reeves DC, Jansen M, Bali M, Lemster T, Akabas MH. A role for the beta 1-beta 2 loop in the gating of 5-HT3 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9358-66. PMID 16221844 DOI: 10.1523/Jneurosci.1045-05.2005  0.71
2003 Jansen M, Potschka H, Brandt C, Löscher W, Dannhardt G. Hydantoin-substituted 4,6-dichloroindole-2-carboxylic acids as ligands with high affinity for the glycine binding site of the NMDA receptor. Journal of Medicinal Chemistry. 46: 64-73. PMID 12502360 DOI: 10.1021/Jm020955N  0.31
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