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Mary Jeanne Kreek - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
Substance Abuse, Addiction
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Year Citation  Score
2024 Zhang Y, Randesi M, Blendy JA, Kreek MJ, Butelman ER. Impact of OPRM1 (Mu-opioid Receptor Gene) A112G Polymorphism on Dual Oxycodone and Cocaine Self-administration Behavior in a Mouse Model. Neuroscience. PMID 38211933 DOI: 10.1016/j.neuroscience.2024.01.002  0.399
2021 Yuferov V, Butelman ER, Randesi M, Ott J, Kreek MJ. Analyses of polymorphisms of intron 2 of OPRK1 (kappa-opioid receptor gene) in association with opioid and cocaine dependence diagnoses in an African-American population. Neuroscience Letters. 768: 136364. PMID 34843875 DOI: 10.1016/j.neulet.2021.136364  0.415
2021 Windisch KA, Mazid S, Johnson MA, Ashirova E, Zhou Y, Gergoire L, Warwick S, McEwen BS, Kreek MJ, Milner TA. Acute Delta 9-tetrahydrocannabinol administration differentially alters the hippocampal opioid system in adult female and male rats. Synapse (New York, N.Y.). PMID 34255372 DOI: 10.1002/syn.22218  0.781
2021 Butelman ER, Chen CY, Brown KG, Lake KJ, Kreek MJ. Age of onset of heaviest use of cannabis or alcohol in persons with severe opioid or cocaine use disorders. Drug and Alcohol Dependence. 226: 108834. PMID 34216857 DOI: 10.1016/j.drugalcdep.2021.108834  0.358
2021 Windisch KA, Morochnik M, Reed B, Kreek MJ. Nalmefene, a Mu Opioid Receptor Antagonist/Kappa Opioid Receptor Partial Agonist, Potentiates Cocaine Motivation But Not Intake with Extended Access Self-Administration in Adult Male Mice. Neuropharmacology. 108590. PMID 33974940 DOI: 10.1016/j.neuropharm.2021.108590  0.825
2021 Yuferov V, Butelman ER, Randesi M, van den Brink W, Blanken P, van Ree JM, Kreek MJ. Association of Serotonin Transporter (SERT) Polymorphisms with Opioid Dependence and Dimensional Aspects of Cocaine Use in a Caucasian Cohort of Opioid Users. Neuropsychiatric Disease and Treatment. 17: 659-670. PMID 33658787 DOI: 10.2147/NDT.S286536  0.382
2020 Rubin BR, Johnson MA, Berman JM, Goldstein E, Pertsovskaya V, Zhou Y, Contoreggi NH, Dyer AG, Gray JD, Waters EM, McEwen BS, Kreek MJ, Milner TA. Sex and chronic stress alter delta opioid receptor distribution within rat hippocampal CA1 pyramidal cells following behavioral challenges. Neurobiology of Stress. 13: 100236. PMID 33344692 DOI: 10.1016/J.Ynstr.2020.100236  0.343
2020 Peles E, Levran O, Randesi M, Ott J, Kreek MJ, Adelson M. Polymorphisms in Stress-Related Genes Are Associated with Reduced Cocaine Abuse and Longer Retention in Methadone Maintenance Treatment for Opioid Use Disorder. European Addiction Research. 1-8. PMID 33242852 DOI: 10.1159/000511898  0.313
2020 Reed B, Butelman ER, Kreek MJ. Kappa Opioid Receptor Antagonists as Potential Therapeutics for Mood and Substance Use Disorders. Handbook of Experimental Pharmacology. PMID 33174064 DOI: 10.1007/164_2020_401  0.343
2020 Butelman ER, Chen CY, Lake KJ, Brown KG, Kreek MJ. Bidirectional influence of heroin and cocaine escalation in persons with dual opioid and cocaine dependence diagnoses. Experimental and Clinical Psychopharmacology. PMID 33119382 DOI: 10.1037/pha0000401  0.364
2020 Windisch KA, Kreek MJ. Review of addiction risk potential associated with adolescent opioid use. Pharmacology, Biochemistry and Behavior. 198: 173022. PMID 32871141 DOI: 10.1016/J.Pbb.2020.173022  0.791
2020 Randesi M, Rotrosen J, Nunes EV, Lee JD, Novo P, Levran O, Ott J, Pavlicova M, Scodes J, Kreek MJ. Variants of opioid genes and response to treatment of opioid use disorder with buprenorphine-naloxone versus extended-release naltrexone in Caucasians. The American Journal of Drug and Alcohol Abuse. 1-8. PMID 32851876 DOI: 10.1080/00952990.2020.1797064  0.415
2020 Zhang Y, Kreek MJ. Nalfurafine modulates the reinforcing effects of oxycodone in male and female adolescent C57BL/6J mice. Neuropharmacology. 108244. PMID 32702404 DOI: 10.1016/J.Neuropharm.2020.108244  0.386
2020 Ashirova E, Contoreggi NH, Johnson MA, Al-Khayat FJ, Calcano GA, Rubin BR, O'Cinneide EM, Zhang Y, Zhou Y, Gregoire L, McEwen BS, Kreek MJ, Milner TA. Oxycodone injections not paired with conditioned place preference have little effect on the hippocampal opioid system in female and male rats. Synapse (New York, N.Y.). e22182. PMID 32654187 DOI: 10.1002/Syn.22182  0.395
2020 Kreek MJ, Zhang Y, Windisch KA, Dunn A. The Laboratory of the Biology of Addictive Diseases: Four Women in Neuroscience. Journal of Neuroscience Research. PMID 32640494 DOI: 10.1002/Jnr.24612  0.744
2020 Dunn A, Windisch K, Ben-Ezra A, Pikus P, Morochnik M, Erazo J, Reed B, Kreek MJ. Modulation of cocaine-related behaviors by low doses of the potent KOR agonist nalfurafine in male C57BL6 mice. Psychopharmacology. PMID 32435819 DOI: 10.1007/S00213-020-05543-7  0.811
2020 Reed B, Kreek MJ. Genetic Vulnerability to Opioid Addiction. Cold Spring Harbor Perspectives in Medicine. PMID 32205416 DOI: 10.1101/Cshperspect.A039735  0.41
2020 Butelman ER, Fry RS, Kimani R, Reed B, Kreek MJ. Neuroendocrine effects of naltrexone versus nalmefene in humans. Human Psychopharmacology. e2726. PMID 32050055 DOI: 10.1002/Hup.2726  0.384
2020 Valenza M, Windisch KA, Butelman ER, Reed B, Kreek MJ. Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat. Psychopharmacology. PMID 31915862 DOI: 10.1007/S00213-019-05444-4  0.817
2019 Collins D, Zhang Y, Blendy J, Kreek MJ. Murine model of OPRM1 A118G alters oxycodone self-administration and locomotor activation, but not conditioned place preference. Neuropharmacology. 107864. PMID 31778689 DOI: 10.1016/J.Neuropharm.2019.107864  0.442
2019 Butelman ER, Chen CY, Brown KG, Kreek MJ. Escalation of drug use in persons dually diagnosed with opioid and cocaine dependence: Gender comparison and dimensional predictors. Drug and Alcohol Dependence. 205: 107657. PMID 31698322 DOI: 10.1016/J.Drugalcdep.2019.107657  0.438
2019 Levran O, Randesi M, Rotrosen J, Ott J, Adelson M, Kreek MJ. A 3' UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction. Plos One. 14: e0224399. PMID 31689297 DOI: 10.1371/Journal.Pone.0224399  0.328
2019 Zhou Y, Kreek MJ. Kappa Opioid Receptors and Mu Opioid Receptors as Combined Targets for Medication Development for Alcoholism. Biological Psychiatry. 86: 809-810. PMID 31668221 DOI: 10.1016/J.Biopsych.2019.08.011  0.39
2019 Kreek MJ, Reed B, Butelman ER. Current status of opioid addiction treatment and related preclinical research. Science Advances. 5: eaax9140. PMID 31616793 DOI: 10.1126/Sciadv.Aax9140  0.377
2019 Bellamy JR, Rubin BR, Zverovich A, Zhou Y, Contoreggi NH, Gray JD, McEwen BS, Kreek MJ, Milner TA. Sex and chronic stress differentially alter phosphorylated mu and delta opioid receptor levels in the rat hippocampus following oxycodone conditioned place preference. Neuroscience Letters. 134514. PMID 31560995 DOI: 10.1016/J.Neulet.2019.134514  0.371
2019 Butelman ER, Chen CY, Conybeare RA, Brown KG, Fry RS, Kimani R, Correa da Rosa J, Ott J, Kreek MJ. Are trait impulsivity and exposure to cannabis or alcohol associated with the age of trajectory of cocaine use? A gender-specific dimensional analysis in humans with cocaine dependence diagnosis. Experimental and Clinical Psychopharmacology. PMID 31424236 DOI: 10.1037/Pha0000314  0.395
2019 Zhou Y, Liang Y, Low MJ, Kreek MJ. Nuclear transcriptional changes in hypothalamus of Pomc enhancer knockout mice after excessive alcohol drinking. Genes, Brain, and Behavior. e12600. PMID 31339663 DOI: 10.1111/Gbb.12600  0.328
2019 Dunn A, Reed B, Erazo J, Ben-Ezra A, Kreek MJ. Signaling properties of structurally diverse kappa opioid receptor ligands: towards in vitro models of in vivo responses. Acs Chemical Neuroscience. PMID 31313902 DOI: 10.1021/Acschemneuro.9B00195  0.316
2019 Randesi M, Contoreggi NH, Zhou Y, Reich B, Bellamy JR, Yu F, Gray JD, McEwen BS, Milner TA, Kreek MJ. Sex differences in neuroplasticity- and stress-related gene expression and protein levels in the rat hippocampus following oxycodone conditioned place preference. Neuroscience. PMID 31071414 DOI: 10.1016/J.Neuroscience.2019.04.047  0.352
2019 Randesi M, van den Brink W, Levran O, Blanken P, van Ree JM, Ott J, Kreek MJ. VMAT2 gene (SLC18A2) variants associated with a greater risk for developing opioid dependence. Pharmacogenomics. PMID 30983500 DOI: 10.2217/Pgs-2018-0137  0.36
2019 Yuferov V, Randesi M, Butelman ER, van den Brink W, Blanken P, van Ree JM, Ott J, Kreek MJ. Association of variants of prodynorphin promoter 68-bp repeats in caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use. Neuroscience Letters. 704: 100-105. PMID 30936032 DOI: 10.1016/J.Neulet.2019.03.038  0.426
2019 Zhou Y, Kreek MJ. Combination of clinically utilized kappa opioid receptor agonist nalfurafine with low-dose naltrexone reduces excessive alcohol drinking in male and female mice. Alcoholism, Clinical and Experimental Research. PMID 30908671 DOI: 10.1111/Acer.14033  0.391
2019 Peles E, Levran O, Randesi M, Ott J, Kreek MJ, Adelson M. Genetic Variant in the CRH-binding Protein Gene (CRHBP) is Associated With Cessation of Cocaine Use in Methadone Maintenance Patients With Opioid Addiction. Journal of Addiction Medicine. PMID 30844877 DOI: 10.1097/Adm.0000000000000515  0.432
2019 Reich B, Zhou Y, Goldstein E, Srivats SS, Contoreggi NH, Kogan JF, McEwen BS, Kreek MJ, Milner TA, Gray JD. Chronic immobilization stress primes the hippocampal opioid system for oxycodone associated learning in female but not male rats. Synapse (New York, N.Y.). PMID 30632204 DOI: 10.1002/Syn.22088  0.313
2018 Windisch KA, Reed B, Kreek MJ. Naltrexone and Nalmefene Attenuate Cocaine Place Preference in Male Mice. Neuropharmacology. PMID 30048644 DOI: 10.1016/J.Neuropharm.2018.07.025  0.823
2018 Butelman ER, Chen CY, Fry RS, Kimani R, Levran O, Ott J, Correa da Rosa J, Kreek MJ. Re-evaluation of the KMSK scales, rapid dimensional measures of self-exposure to specific drugs: Gender-specific features. Drug and Alcohol Dependence. 190: 179-187. PMID 30041093 DOI: 10.1016/J.Drugalcdep.2018.05.028  0.315
2018 Butelman ER, Maremmani AGI, Bacciardi S, Chen CY, Correa da Rosa J, Kreek MJ. Non-medical Cannabis Self-Exposure as a Dimensional Predictor of Opioid Dependence Diagnosis: A Propensity Score Matched Analysis. Frontiers in Psychiatry. 9: 283. PMID 29997535 DOI: 10.3389/fpsyt.2018.00283  0.318
2018 Randesi M, Zhou Y, Mazid S, Odell SC, Gray JD, Correa da Rosa J, McEwen BS, Milner TA, Kreek MJ. Sex differences after chronic stress in the expression of opioid-, stress- and neuroplasticity-related genes in the rat hippocampus. Neurobiology of Stress. 8: 33-41. PMID 29888302 DOI: 10.1016/J.Ynstr.2018.01.001  0.35
2018 Yuferov V, Butelman ER, Kreek MJ. Gender-specific association of functional prodynorphin 68 bp repeats with cannabis exposure in an African American cohort. Neuropsychiatric Disease and Treatment. 14: 1025-1034. PMID 29713172 DOI: 10.2147/Ndt.S159954  0.347
2018 Dunn AD, Reed B, Guariglia C, Dunn AM, Hillman JM, Kreek MJ. Structurally-Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice. The International Journal of Neuropsychopharmacology. PMID 29635340 DOI: 10.1093/Ijnp/Pyy034  0.375
2017 Butelman ER, Kreek MJ. Medications for substance use disorders (SUD): emerging approaches. Expert Opinion On Emerging Drugs. 22: 301-315. PMID 29057665 DOI: 10.1080/14728214.2017.1395855  0.309
2017 Levran O, Peles E, Randesi M, da Rosa JC, Adelson M, Kreek MJ. The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment. Pharmacogenomics. PMID 28976288 DOI: 10.2217/Pgs-2017-0092  0.424
2017 Reed B, Butelman ER, Fry R, Kimani R, Kreek MJ. Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and Without Cocaine Dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28857070 DOI: 10.1038/npp.2017.205  0.346
2017 Butelman ER, Bacciardi S, Maremmani AGI, Darst-Campbell M, Rosa JCd, Kreek MJ. Can a rapid measure of self‐exposure to drugs of abuse provide dimensional information on depression comorbidity? American Journal On Addictions. 26: 632-639. PMID 28654734 DOI: 10.1111/Ajad.12578  0.39
2017 Zhang Y, Liang Y, Levran O, Randesi M, Yuferov V, Zhao C, Kreek MJ. Alterations of expression of inflammation/immune-related genes in the dorsal and ventral striatum of adult C57BL/6J mice following chronic oxycodone self-administration: a RNA sequencing study. Psychopharmacology. PMID 28653080 DOI: 10.1007/S00213-017-4657-Y  0.405
2017 Valenza M, Butelman ER, Kreek MJ. "Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats". Psychopharmacology. PMID 28550455 DOI: 10.1007/S00213-017-4647-0  0.593
2017 Randesi M, Levran O, Correa da Rosa J, Hankins J, Rule J, Kreek MJ, Lee WM. Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury. Cellular and Molecular Gastroenterology and Hepatology. 3: 500-505. PMID 28462386 DOI: 10.1016/J.Jcmgh.2017.01.008  0.376
2017 Randesi M, Levran O, Ott J, Blanken P, Brink Wvd, Ree JMv, Kreek MJ. Gene variants of the dopaminergic system are associated with non-dependent heroin use and heroin dependence Drug and Alcohol Dependence. 171. DOI: 10.1016/J.Drugalcdep.2016.08.476  0.32
2017 Guariglia C, Dunn A, Windisch K, Butelman E, Reed B, Kreek MJ. Partial kappa opioid receptor agonist effects in vivo in mice: Biased versus unbiased Drug and Alcohol Dependence. 171. DOI: 10.1016/J.Drugalcdep.2016.08.223  0.792
2017 Reed B, Butelman ER, Kreek MJ. Endogenous opioid system in addiction and addiction-related behaviors Current Opinion in Behavioral Sciences. 13: 196-202. DOI: 10.1016/J.Cobeha.2016.12.002  0.487
2016 Randesi M, van den Brink W, Levran O, Blanken P, Butelman ER, Yuferov V, da Rosa JC, Ott J, van Ree JM, Kreek MJ. Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence. Drug and Alcohol Dependence. 168: 164-169. PMID 27664554 DOI: 10.1016/J.Drugalcdep.2016.08.634  0.442
2016 Zhang Y, Windisch K, Altschuler J, Rahm S, Butelman ER, Kreek MJ. Adolescent oxycodone self administration alters subsequent oxycodone-induced conditioned place preference and anti-nociceptive effect in C57BL/6J mice in adulthood. Neuropharmacology. PMID 27614221 DOI: 10.1016/j.neuropharm.2016.09.005  0.766
2016 Collins D, Reed B, Zhang Y, Kreek MJ. Sex differences in responsiveness to the prescription opioid oxycodone in mice. Pharmacology, Biochemistry, and Behavior. PMID 27316549 DOI: 10.1016/J.Pbb.2016.06.006  0.312
2016 Levran O, Randesi M, Peles E, Correa da Rosa J, Ott J, Rotrosen J, Adelson M, Kreek MJ. African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction. Pharmacogenomics. PMID 27269905 DOI: 10.2217/Pgs-2016-0028  0.475
2016 Butelman ER, Kreek MJ. Discriminative Stimulus Properties of Opioid Ligands: Progress and Future Directions. Current Topics in Behavioral Neurosciences. 39: 175-192. PMID 27225498 DOI: 10.1007/7854_2016_9  0.319
2016 Valenza M, Picetti R, Yuferov V, Butelman ER, Kreek MJ. Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration. Neuropharmacology. PMID 26777278 DOI: 10.1016/J.Neuropharm.2016.01.004  0.626
2015 Butelman ER, Kreek MJ. Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders. Frontiers in Pharmacology. 6: 190. PMID 26441647 DOI: 10.3389/Fphar.2015.00190  0.411
2015 Schwantes-An TH, Zhang J, Chen LS, Hartz SM, Culverhouse RC, Chen X, Coon H, Frank J, Kamens HM, Konte B, Kovanen L, Latvala A, Legrand LN, Maher BS, Melroy WE, ... ... Kreek MJ, et al. Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. Behavior Genetics. PMID 26392368 DOI: 10.1007/S10519-015-9737-3  0.422
2015 Levran O, Peles E, Randesi M, Correa da Rosa J, Ott J, Rotrosen J, Adelson M, Kreek MJ. Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry. Cns Neuroscience & Therapeutics. 21: 898-904. PMID 26384852 DOI: 10.1111/Cns.12450  0.33
2015 Levran O, Peles E, Randesi M, Correa da Rosa J, Ott J, Rotrosen J, Adelson M, Kreek MJ. Susceptibility loci for heroin and cocaine addiction in the serotonergic and adrenergic pathways in populations of different ancestry. Pharmacogenomics. 1-14. PMID 26227246 DOI: 10.2217/Pgs.15.86  0.397
2015 Levy A, Marshall P, Zhou Y, Kreek MJ, Kent K, Daniels S, Shore A, Downs T, Fernandes MF, Mutch DM, Leri F. Fructose:glucose ratios--a study of sugar self-administration and associated neural and physiological responses in the rat. Nutrients. 7: 3869-90. PMID 26007337 DOI: 10.3390/Nu7053869  0.334
2015 Levran O, Randesi M, da Rosa JC, Ott J, Rotrosen J, Adelson M, Kreek MJ. Overlapping dopaminergic pathway genetic susceptibility to heroin and cocaine addictions in African Americans. Annals of Human Genetics. 79: 188-98. PMID 25875614 DOI: 10.1111/Ahg.12104  0.376
2015 Zhou Y, Kreek MJ. Persistent increases in rat hypothalamic POMC gene expression following chronic withdrawal from chronic "binge" pattern escalating-dose, but not steady-dose, cocaine. Neuroscience. 289: 63-70. PMID 25595971 DOI: 10.1016/J.Neuroscience.2014.12.078  0.455
2015 Zhang Y, Brownstein AJ, Buonora M, Niikura K, Ho A, Correa da Rosa J, Kreek MJ, Ott J. Self administration of oxycodone alters synaptic plasticity gene expression in the hippocampus differentially in male adolescent and adult mice. Neuroscience. 285: 34-46. PMID 25446355 DOI: 10.1016/J.Neuroscience.2014.11.013  0.375
2015 Zhou Y, Leri F, Cummins E, Kreek MJ. Individual differences in gene expression of vasopressin, D2 receptor, POMC and orexin: vulnerability to relapse to heroin-seeking in rats. Physiology & Behavior. 139: 127-35. PMID 25446223 DOI: 10.1016/J.Physbeh.2014.11.002  0.371
2015 Valenza M, Picetti R, Yuferov V, Kreek MJ. Predisposing genetic differences contribute to vulnerability to escalate cocaine intake in rats Drug and Alcohol Dependence. 146: e9. DOI: 10.1016/J.Drugalcdep.2014.09.705  0.569
2015 Ray BM, Ducat EA, Reed B, Altschuler J, Kreek MJ. CRF versus AVP in human stress responsivity: Initial studies Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.577  0.306
2015 Randesi M, Levran O, Butelman E, Yuferov V, Ott J, Blanken P, Brink Wvd, Ree JMv, Kreek MJ. Gene variants of the opioid system – Relationship to heroin self-exposure, addiction, and treatment Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.575  0.396
2015 Levran O, Peles E, Randesi M, Li Y, Rotrosen J, Ott J, Adelson M, Kreek MJ. Stress-related genes and heroin addiction: A role for functional fkbp5 variants Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.395  0.407
2015 Ducat EA, Ray BM, Jackson J, Butelman E, Kreek MJ. Basal neuroendocrine status and cocaine craving measurements in active cocaine-dependent volunteers at admission and after 8 weeks of abstinence Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.198  0.41
2014 Levran O, Peles E, Randesi M, Correa da Rosa J, Ott J, Rotrosen J, Adelson M, Kreek MJ. Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants. Pharmacogenomics. 15: 2001-9. PMID 25521358 DOI: 10.2217/Pgs.14.145  0.338
2014 Zaaijer ER, Bruijel J, Blanken P, Hendriks V, Koeter MW, Kreek MJ, Booij J, Goudriaan AE, van Ree JM, van den Brink W. Personality as a risk factor for illicit opioid use and a protective factor for illicit opioid dependence. Drug and Alcohol Dependence. 145: 101-5. PMID 25454407 DOI: 10.1016/J.Drugalcdep.2014.09.783  0.376
2014 Reed B, Butelman ER, Yuferov V, Randesi M, Kreek MJ. Genetics of opiate addiction. Current Psychiatry Reports. 16: 504. PMID 25209027 DOI: 10.1007/S11920-014-0504-6  0.372
2014 Zhou Y, Kreek MJ. Alcohol: a stimulant activating brain stress responsive systems with persistent neuroadaptation. Neuropharmacology. 87: 51-8. PMID 24929109 DOI: 10.1016/J.Neuropharm.2014.05.044  0.384
2014 Levran O, Peles E, Randesi M, Li Y, Rotrosen J, Ott J, Adelson M, Kreek MJ. Stress-related genes and heroin addiction: a role for a functional FKBP5 haplotype. Psychoneuroendocrinology. 45: 67-76. PMID 24845178 DOI: 10.1016/J.Psyneuen.2014.03.017  0.311
2014 Levran O, Randesi M, Li Y, Rotrosen J, Ott J, Adelson M, Kreek MJ. Drug addiction and stress-response genetic variability: association study in African Americans. Annals of Human Genetics. 78: 290-8. PMID 24766650 DOI: 10.1111/Ahg.12064  0.376
2014 Zhang Y, Mayer-Blackwell B, Schlussman SD, Randesi M, Butelman ER, Ho A, Ott J, Kreek MJ. Extended access oxycodone self-administration and neurotransmitter receptor gene expression in the dorsal striatum of adult C57BL/6 J mice. Psychopharmacology. 231: 1277-87. PMID 24221825 DOI: 10.1007/S00213-013-3306-3  0.319
2014 Mayer-Blackwell B, Schlussman SD, Butelman ER, Ho A, Ott J, Kreek MJ, Zhang Y. Self administration of oxycodone by adolescent and adult mice affects striatal neurotransmitter receptor gene expression. Neuroscience. 258: 280-91. PMID 24220688 DOI: 10.1016/J.Neuroscience.2013.10.062  0.344
2014 Zhang Y, Deutsch-Feldman M, Buonora M, Brownstein AJ, Niikura K, Ho A, Jurgott, Kreek MJ. Self-Administrationof Oxycodone by Adolescent and Adult Mice Differentially Affects Hypothalamic Mitochondrial Metabolism Gene Expression Journal of Alcoholism and Drug Dependence. 2: 1-6. DOI: 10.4172/2329-6488.1000153  0.335
2014 Zhou Y, Litvin Y, Pfaff D, Kreek M. Involvement of KOP-r in cocaine withdrawal-induced conditioned place aversion in rats Drug and Alcohol Dependence. 140: e250. DOI: 10.1016/J.Drugalcdep.2014.02.692  0.355
2014 Brownstein AJ, Zhang Y, Picetti R, Butelman E, Schlussman SD, Ho A, Aldrich JV, Kreek MJ. Effects of the short-acting KOP-r antagonist [D-TRP]CJ-15,208 on cocaine self-administration, locomotor activity, and food intake in male C57/BL6 mice Drug and Alcohol Dependence. 140. DOI: 10.1016/J.Drugalcdep.2014.02.081  0.417
2013 Peles E, Linzy S, Kreek MJ, Adelson M. Prospective study of QTc changes among former opiate addicts since admission to methadone maintenance treatment: benzodiazepine risk. Journal of Addiction Medicine. 7: 428-34. PMID 24145160 DOI: 10.1097/Adm.0B013E3182A8A4F2  0.384
2013 Lawhorn C, Yuferov V, Randesi M, Ho A, Morgello S, Kreek MJ, Levran O. Genetic diversity and linkage disequilibrium in the chemokine receptor CCR2-CCR5 region among individuals and populations. Cytokine. 64: 571-6. PMID 24011637 DOI: 10.1016/J.Cyto.2013.08.008  0.716
2013 Lawhorn C, Edusei E, Zhou Y, Ho A, Kreek MJ. Acute binge pattern cocaine administration induces region-specific effects in D1-r- and D2-r-expressing cells in eGFP transgenic mice. Neuroscience. 253: 123-31. PMID 24001687 DOI: 10.1016/J.Neuroscience.2013.08.032  0.747
2013 Niikura K, Ho A, Kreek MJ, Zhang Y. Oxycodone-induced conditioned place preference and sensitization of locomotor activity in adolescent and adult mice. Pharmacology, Biochemistry, and Behavior. 110: 112-6. PMID 23827650 DOI: 10.1016/J.Pbb.2013.06.010  0.319
2013 Zhou Y, Leri F, Ho A, Kreek MJ. Suppression of hypothalamic-pituitary-adrenal axis by acute heroin challenge in rats during acute and chronic withdrawal from chronic heroin administration. Neurochemical Research. 38: 1850-60. PMID 23771528 DOI: 10.1007/S11064-013-1091-3  0.344
2013 Levran O, Peles E, Randesi M, Shu X, Ott J, Shen PH, Adelson M, Kreek MJ. Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction. Pharmacogenomics. 14: 755-68. PMID 23651024 DOI: 10.2217/Pgs.13.58  0.388
2013 Picetti R, Schlussman SD, Zhou Y, Ray B, Ducat E, Yuferov V, Kreek MJ. Addictions and stress: clues for cocaine pharmacotherapies. Current Pharmaceutical Design. 19: 7065-80. PMID 23574443 DOI: 10.2174/13816128113199990610  0.491
2013 Zhou Y, Leri F, Grella SL, Aldrich JV, Kreek MJ. Involvement of dynorphin and kappa opioid receptor in yohimbine-induced reinstatement of heroin seeking in rats. Synapse (New York, N.Y.). 67: 358-61. PMID 23345075 DOI: 10.1002/Syn.21638  0.424
2013 Niikura K, Zhou Y, Ho A, Kreek MJ. Proopiomelanocortin (POMC) expression and conditioned place aversion during protracted withdrawal from chronic intermittent escalating-dose heroin in POMC-EGFP promoter transgenic mice. Neuroscience. 236: 220-32. PMID 23337531 DOI: 10.1016/J.Neuroscience.2012.12.071  0.346
2013 Zhang Y, Schlussman SD, Rabkin J, Butelman ER, Ho A, Kreek MJ. Chronic escalating cocaine exposure, abstinence/withdrawal, and chronic re-exposure: effects on striatal dopamine and opioid systems in C57BL/6J mice. Neuropharmacology. 67: 259-66. PMID 23164614 DOI: 10.1016/J.Neuropharm.2012.10.015  0.61
2013 Seip-Cammack KM, Reed B, Zhang Y, Ho A, Kreek MJ. Tolerance and sensitization to chronic escalating dose heroin following extended withdrawal in Fischer rats: possible role of mu-opioid receptors. Psychopharmacology. 225: 127-40. PMID 22829433 DOI: 10.1007/S00213-012-2801-2  0.393
2013 Levran O, Peles E, Hamon S, Randesi M, Adelson M, Kreek MJ. CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction. Addiction Biology. 18: 709-16. PMID 21790905 DOI: 10.1111/J.1369-1600.2011.00349.X  0.33
2013 Ducat E, Ray B, Bart G, Umemura Y, Varon J, Ho A, Kreek MJ. Mu-opioid receptor A118G polymorphism in healthy volunteers affects hypothalamic-pituitary-adrenal axis adrenocorticotropic hormone stress response to metyrapone. Addiction Biology. 18: 325-31. PMID 21507151 DOI: 10.1111/J.1369-1600.2011.00313.X  0.426
2012 Zhou Y, Kruyer A, Ho A, Kreek MJ. Cocaine place conditioning increases pro-opiomelanocortin gene expression in rat hypothalamus. Neuroscience Letters. 530: 59-63. PMID 23069669 DOI: 10.1016/J.Neulet.2012.09.060  0.441
2012 Kreek MJ, Levran O, Reed B, Schlussman SD, Zhou Y, Butelman ER. Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics. The Journal of Clinical Investigation. 122: 3387-93. PMID 23023708 DOI: 10.1172/Jci60390  0.472
2012 Butelman ER, Yuferov V, Kreek MJ. κ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addiction. Trends in Neurosciences. 35: 587-96. PMID 22709632 DOI: 10.1016/J.Tins.2012.05.005  0.506
2012 Reed B, Fang N, Mayer-Blackwell B, Chen S, Yuferov V, Zhou Y, Kreek MJ. Chromatin alterations in response to forced swimming underlie increased prodynorphin transcription. Neuroscience. 220: 109-18. PMID 22698692 DOI: 10.1016/J.Neuroscience.2012.06.006  0.356
2012 Levran O, Yuferov V, Kreek MJ. The genetics of the opioid system and specific drug addictions. Human Genetics. 131: 823-42. PMID 22547174 DOI: 10.1007/S00439-012-1172-4  0.466
2012 Nielsen DA, Kreek MJ. Common and specific liability to addiction: approaches to association studies of opioid addiction. Drug and Alcohol Dependence. 123: S33-41. PMID 22542464 DOI: 10.1016/J.Drugalcdep.2012.03.026  0.64
2012 Zhang Y, Schlussman SD, Butelman ER, Ho A, Kreek MJ. Effects of withdrawal from chronic escalating-dose binge cocaine on conditioned place preference to cocaine and striatal preproenkephalin mRNA in C57BL/6J mice. Neuropharmacology. 63: 322-9. PMID 22504589 DOI: 10.1016/J.Neuropharm.2012.03.021  0.448
2012 Lovell KM, Vasiljevik T, Araya JJ, Lozama A, Prevatt-Smith KM, Day VW, Dersch CM, Rothman RB, Butelman ER, Kreek MJ, Prisinzano TE. Semisynthetic neoclerodanes as kappa opioid receptor probes. Bioorganic & Medicinal Chemistry. 20: 3100-10. PMID 22464684 DOI: 10.1016/J.Bmc.2012.02.040  0.338
2012 Butelman ER, Caspers M, Lovell KM, Kreek MJ, Prisinzano TE. Behavioral effects and central nervous system levels of the broadly available κ-agonist hallucinogen salvinorin A are affected by P-glycoprotein modulation in vivo. The Journal of Pharmacology and Experimental Therapeutics. 341: 802-8. PMID 22434677 DOI: 10.1124/Jpet.112.193227  0.327
2012 Nielsen DA, Ho A, Bahl A, Varma P, Kellogg S, Borg L, Kreek MJ. Former heroin addicts with or without a history of cocaine dependence are more impulsive than controls. Drug and Alcohol Dependence. 124: 113-20. PMID 22265192 DOI: 10.1016/J.Drugalcdep.2011.12.022  0.629
2012 Vanyukov MM, Tarter RE, Kirillova GP, Kirisci L, Reynolds MD, Kreek MJ, Conway KP, Maher BS, Iacono WG, Bierut L, Neale MC, Clark DB, Ridenour TA. Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective. Drug and Alcohol Dependence. 123: S3-17. PMID 22261179 DOI: 10.1016/J.Drugalcdep.2011.12.018  0.3
2012 Picetti R, Caccavo JA, Ho A, Kreek MJ. Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats. Psychopharmacology. 220: 163-72. PMID 21894484 DOI: 10.1007/S00213-011-2464-4  0.33
2012 Seip KM, Reed B, Ho A, Kreek MJ. Measuring the incentive value of escalating doses of heroin in heroin-dependent Fischer rats during acute spontaneous withdrawal. Psychopharmacology. 219: 59-72. PMID 21748254 DOI: 10.1007/S00213-011-2380-7  0.362
2012 Leri F, Zhou Y, Carmichael B, Cummins E, Kreek MJ. Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 22: 143-52. PMID 21745729 DOI: 10.1016/J.Euroneuro.2011.06.003  0.468
2012 Levran O, Peles E, Hamon S, Randesi M, Zhao C, Zhang B, Adelson M, Kreek MJ. Nerve growth factor β polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment. The Pharmacogenomics Journal. 12: 319-27. PMID 21358750 DOI: 10.1038/Tpj.2011.6  0.354
2012 Crystal HA, Hamon S, Randesi M, Cook J, Anastos K, Lazar J, Liu C, Pearce L, Golub E, Valcour V, Weber KM, Holman S, Ho A, Kreek MJ. A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women. Addiction Biology. 17: 181-91. PMID 21070507 DOI: 10.1111/J.1369-1600.2010.00265.X  0.365
2012 Nielsen DA, Proudnikov D, Kreek MJ. The Genetics of Impulsivity The Oxford Handbook of Impulse Control Disorders. DOI: 10.1093/oxfordhb/9780195389715.013.0080  0.424
2011 Martin JA, Campbell A, Killip T, Kotz M, Krantz MJ, Kreek MJ, McCarroll BA, Mehta D, Payte JT, Stimmel B, Taylor T, Haigney MC, Wilford BB. QT interval screening in methadone maintenance treatment: report of a SAMHSA expert panel. Journal of Addictive Diseases. 30: 283-306. PMID 22026519 DOI: 10.1080/10550887.2011.610710  0.316
2011 Kreek MJ, Zhou Y, Levran O. Functions of arginine vasopressin and its receptors: importance of human molecular genetics studies in bidirectional translational research. Biological Psychiatry. 70: 502-3. PMID 21864735 DOI: 10.1016/J.Biopsych.2011.07.013  0.315
2011 Zhou Y, Litvin Y, Piras AP, Pfaff DW, Kreek MJ. Persistent increase in hypothalamic arginine vasopressin gene expression during protracted withdrawal from chronic escalating-dose cocaine in rodents. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2062-75. PMID 21677651 DOI: 10.1038/Npp.2011.97  0.48
2011 Lane DA, Reed B, Kreek MJ, Pickel VM. Differential glutamate AMPA-receptor plasticity in subpopulations of VTA neurons in the presence or absence of residual cocaine: implications for the development of addiction. Neuropharmacology. 61: 1129-40. PMID 21215761 DOI: 10.1016/J.Neuropharm.2010.12.031  0.414
2011 Levran O, Awolesi O, Linzy S, Adelson M, Kreek MJ. Haplotype block structure of the genomic region of the mu opioid receptor gene. Journal of Human Genetics. 56: 147-55. PMID 21160491 DOI: 10.1038/Jhg.2010.150  0.378
2011 Yuferov V, Nielsen DA, Levran O, Randesi M, Hamon S, Ho A, Morgello S, Kreek MJ. Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs. Pharmacogenetics and Genomics. 21: 185-96. PMID 20808262 DOI: 10.1097/Fpc.0B013E32833Eecbc  0.539
2011 Rouault M, Nielsen DA, Ho A, Kreek MJ, Yuferov V. Cell-specific effects of variants of the 68-base pair tandem repeat on prodynorphin gene promoter activity. Addiction Biology. 16: 334-46. PMID 20731629 DOI: 10.1111/J.1369-1600.2010.00248.X  0.527
2010 Ho MK, Goldman D, Heinz A, Kaprio J, Kreek MJ, Li MD, Munafò MR, Tyndale RF. Breaking barriers in the genomics and pharmacogenetics of drug addiction. Clinical Pharmacology and Therapeutics. 88: 779-91. PMID 20981002 DOI: 10.1038/Clpt.2010.175  0.301
2010 Zhou Y, Maiya R, Norris EH, Kreek MJ, Strickland S. Involvement of tissue plasminogen activator in stress responsivity during acute cocaine withdrawal in mice. Stress (Amsterdam, Netherlands). 13: 481-90. PMID 20666641 DOI: 10.3109/10253891003786415  0.418
2010 Picetti R, Ho A, Butelman ER, Kreek MJ. Dose preference and dose escalation in extended-access cocaine self-administration in Fischer and Lewis rats. Psychopharmacology. 211: 313-23. PMID 20559822 DOI: 10.1007/S00213-010-1899-3  0.41
2010 Lane DA, Jaferi A, Kreek MJ, Pickel VM. Acute and chronic cocaine differentially alter the subcellular distribution of AMPA GluR1 subunits in region-specific neurons within the mouse ventral tegmental area. Neuroscience. 169: 559-73. PMID 20553819 DOI: 10.1016/J.Neuroscience.2010.05.056  0.436
2010 Nielsen DA, Ji F, Yuferov V, Ho A, He C, Ott J, Kreek MJ. Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. Psychiatric Genetics. 20: 207-14. PMID 20520587 DOI: 10.1097/Ypg.0B013E32833A2106  0.544
2010 Niikura K, Narita M, Butelman ER, Kreek MJ, Suzuki T. Neuropathic and chronic pain stimuli downregulate central mu-opioid and dopaminergic transmission. Trends in Pharmacological Sciences. 31: 299-305. PMID 20471111 DOI: 10.1016/J.Tips.2010.04.003  0.371
2010 Piras AP, Zhou Y, Schlussman SD, Ho A, Kreek MJ. Acute withdrawal from chronic escalating-dose binge cocaine administration alters kappa opioid receptor stimulation of [35S] guanosine 5'-O-[gamma-thio]triphosphate acid binding in the rat ventral tegmental area. Neuroscience. 169: 751-7. PMID 20452406 DOI: 10.1016/J.Neuroscience.2010.04.060  0.47
2010 Jackson CB, Varon J, Ho A, Marks KM, Talal AH, Kreek MJ. Identification of substance use and dependence among patients with viral hepatitis. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 42: 650-6. PMID 20418192 DOI: 10.1016/J.Dld.2010.03.002  0.386
2010 Kreek MJ, Borg L, Ducat E, Ray B. Pharmacotherapy in the treatment of addiction: methadone. Journal of Addictive Diseases. 29: 200-16. PMID 20407977 DOI: 10.1080/10550881003684798  0.347
2010 Kreek MJ. Overview and historical perspective of four papers presented on research related to the endogenous opioid system. Drug and Alcohol Dependence. 108: 195-9. PMID 20399574 DOI: 10.1016/J.Drugalcdep.2010.03.003  0.358
2010 Nielsen DA, Hamon S, Yuferov V, Jackson C, Ho A, Ott J, Kreek MJ. Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts. Human Genetics. 127: 639-49. PMID 20237803 DOI: 10.1007/S00439-010-0807-6  0.585
2010 Yuferov V, Levran O, Proudnikov D, Nielsen DA, Kreek MJ. Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment. Annals of the New York Academy of Sciences. 1187: 184-207. PMID 20201854 DOI: 10.1111/J.1749-6632.2009.05275.X  0.63
2010 Butelman ER, Rus S, Prisinzano TE, Kreek MJ. The discriminative effects of the kappa-opioid hallucinogen salvinorin A in nonhuman primates: dissociation from classic hallucinogen effects. Psychopharmacology. 210: 253-62. PMID 20084367 DOI: 10.1007/S00213-009-1771-5  0.411
2010 Briant JA, Nielsen DA, Proudnikov D, Londono D, Ho A, Ott J, Kreek MJ. Evidence for association of two variants of the nociceptin/orphanin FQ receptor gene OPRL1 with vulnerability to develop opiate addiction in Caucasians. Psychiatric Genetics. 20: 65-72. PMID 20032820 DOI: 10.1097/Ypg.0B013E32833511F6  0.591
2010 Proudnikov D, Kroslak T, Sipe JC, Randesi M, Li D, Hamon S, Ho A, Ott J, Kreek MJ. Association of polymorphisms of the cannabinoid receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes with heroin addiction: impact of long repeats of CNR1. The Pharmacogenomics Journal. 10: 232-42. PMID 20010914 DOI: 10.1038/Tpj.2009.59  0.338
2010 Waldrop AE, Price KL, Desantis SM, Simpson AN, Back SE, McRae AL, Spratt EG, Kreek MJ, Brady KT. Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues. Psychoneuroendocrinology. 35: 798-806. PMID 20004523 DOI: 10.1016/J.Psyneuen.2009.11.005  0.411
2010 Back SE, Hartwell K, DeSantis SM, Saladin M, McRae-Clark AL, Price KL, Moran-Santa Maria MM, Baker NL, Spratt E, Kreek MJ, Brady KT. Reactivity to laboratory stress provocation predicts relapse to cocaine. Drug and Alcohol Dependence. 106: 21-7. PMID 19726138 DOI: 10.1016/J.Drugalcdep.2009.07.016  0.429
2010 Kreek MJ, Borg L, Zhou Y, Kravets I. Endocrine systems interacting with brain and behavior: Laboratory and clinical studies of heroin and other short-acting opiates versus methadone and other long-acting opioids Hormones, Brain and Behavior Online. 3177-3207. DOI: 10.1016/B978-008088783-8.00100-5  0.442
2009 Fox HC, Hong KI, Siedlarz KM, Bergquist K, Anderson G, Kreek MJ, Sinha R. Sex-specific dissociations in autonomic and HPA responses to stress and cues in alcohol-dependent patients with cocaine abuse. Alcohol and Alcoholism (Oxford, Oxfordshire). 44: 575-85. PMID 19793926 DOI: 10.1093/Alcalc/Agp060  0.323
2009 Levran O, Londono D, O'Hara K, Randesi M, Rotrosen J, Casadonte P, Linzy S, Ott J, Adelson M, Kreek MJ. Heroin addiction in African Americans: a hypothesis-driven association study. Genes, Brain, and Behavior. 8: 531-40. PMID 19500151 DOI: 10.1111/J.1601-183X.2009.00501.X  0.353
2009 Brady KT, McRae AL, Moran-Santa Maria MM, DeSantis SM, Simpson AN, Waldrop AE, Back SE, Kreek MJ. Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals. Archives of General Psychiatry. 66: 422-30. PMID 19349312 DOI: 10.1001/Archgenpsychiatry.2009.9  0.423
2009 Maiya R, Zhou Y, Norris EH, Kreek MJ, Strickland S. Tissue plasminogen activator modulates the cellular and behavioral response to cocaine. Proceedings of the National Academy of Sciences of the United States of America. 106: 1983-8. PMID 19181855 DOI: 10.1073/Pnas.0812491106  0.439
2009 Kreek MJ, Zhou Y, Butelman ER, Levran O. Opiate and cocaine addiction: from bench to clinic and back to the bench. Current Opinion in Pharmacology. 9: 74-80. PMID 19155191 DOI: 10.1016/j.coph.2008.12.016  0.391
2009 Butelman ER, Prisinzano TE, Deng H, Rus S, Kreek MJ. Unconditioned behavioral effects of the powerful kappa-opioid hallucinogen salvinorin A in nonhuman primates: fast onset and entry into cerebrospinal fluid. The Journal of Pharmacology and Experimental Therapeutics. 328: 588-97. PMID 19001155 DOI: 10.1124/Jpet.108.145342  0.374
2009 Leri F, Zhou Y, Goddard B, Levy A, Jacklin D, Kreek MJ. Steady-state methadone blocks cocaine seeking and cocaine-induced gene expression alterations in the rat brain. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19: 238-49. PMID 18990547 DOI: 10.1016/J.Euroneuro.2008.09.004  0.369
2009 Zhang Y, Landthaler M, Schlussman SD, Yuferov V, Ho A, Tuschl T, Kreek MJ. Mu opioid receptor knockdown in the substantia nigra/ventral tegmental area by synthetic small interfering RNA blocks the rewarding and locomotor effects of heroin. Neuroscience. 158: 474-83. PMID 18938225 DOI: 10.1016/J.Neuroscience.2008.09.039  0.361
2009 Yuferov V, Ji F, Nielsen DA, Levran O, Ho A, Morgello S, Shi R, Ott J, Kreek MJ. A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1185-97. PMID 18923396 DOI: 10.1038/Npp.2008.187  0.635
2009 Zhang Y, Picetti R, Butelman ER, Schlussman SD, Ho A, Kreek MJ. Behavioral and neurochemical changes induced by oxycodone differ between adolescent and adult mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 912-22. PMID 18784649 DOI: 10.1038/Npp.2008.134  0.339
2009 Kreek MJ, Schlussman SD, Reed B, Zhang Y, Nielsen DA, Levran O, Zhou Y, Butelman ER. Bidirectional translational research: Progress in understanding addictive diseases. Neuropharmacology. 56: 32-43. PMID 18725235 DOI: 10.1016/j.neuropharm.2008.07.042  0.58
2009 Nielsen DA, Yuferov V, Hamon S, Jackson C, Ho A, Ott J, Kreek MJ. Increased OPRM1 DNA methylation in lymphocytes of methadone-maintained former heroin addicts. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 867-73. PMID 18650805 DOI: 10.1038/Npp.2008.108  0.555
2009 Nielsen DA, Yuferov V, Hamon S, Jackson C, Ho A, Ott J, Kreek MJ. Increased OPRM1 DNA methylation in lymphocytes of methadone (Neuropsychopharmacology (2008) DOI: 10.1038/npp.2008.108) Neuropsychopharmacology. 34: 1087. DOI: 10.1038/Npp.2008.155  0.496
2008 Devidze N, Zhou Y, Ho A, Zhang Q, Pfaff DW, Kreek MJ. Steady-state methadone effect on generalized arousal in male and female mice. Behavioral Neuroscience. 122: 1248-56. PMID 19045944 DOI: 10.1037/A0013276  0.351
2008 Peles E, Linzy S, Kreek MJ, Adelson M. One-year and cumulative retention as predictors of success in methadone maintenance treatment: A comparison of two clinics in the United States and Israel Journal of Addictive Diseases. 27: 11-25. PMID 19042587 DOI: 10.1080/10550880802324382  0.334
2008 Lane DA, Lessard AA, Chan J, Colago EE, Zhou Y, Schlussman SD, Kreek MJ, Pickel VM. Region-specific changes in the subcellular distribution of AMPA receptor GluR1 subunit in the rat ventral tegmental area after acute or chronic morphine administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9670-81. PMID 18815253 DOI: 10.1523/Jneurosci.2151-08.2008  0.365
2008 Butelman ER, Rus S, Simpson DS, Wolf A, Prisinzano TE, Kreek MJ. The effects of herkinorin, the first mu-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in nonhuman primates. The Journal of Pharmacology and Experimental Therapeutics. 327: 154-60. PMID 18593955 DOI: 10.1124/Jpet.108.140079  0.387
2008 Levran O, Londono D, O'Hara K, Nielsen DA, Peles E, Rotrosen J, Casadonte P, Linzy S, Randesi M, Ott J, Adelson M, Kreek MJ. Genetic susceptibility to heroin addiction: a candidate gene association study. Genes, Brain, and Behavior. 7: 720-9. PMID 18518925 DOI: 10.1111/J.1601-183X.2008.00410.X  0.573
2008 Zhou Y, Cui CL, Schlussman SD, Choi JC, Ho A, Han JS, Kreek MJ. Effects of cocaine place conditioning, chronic escalating-dose "binge" pattern cocaine administration and acute withdrawal on orexin/hypocretin and preprodynorphin gene expressions in lateral hypothalamus of Fischer and Sprague-Dawley rats. Neuroscience. 153: 1225-34. PMID 18436386 DOI: 10.1016/j.neuroscience.2008.03.023  0.352
2008 Levran O, O'Hara K, Peles E, Li D, Barral S, Ray B, Borg L, Ott J, Adelson M, Kreek MJ. ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence. Human Molecular Genetics. 17: 2219-27. PMID 18424454 DOI: 10.1093/Hmg/Ddn122  0.343
2008 Proudnikov D, Hamon S, Ott J, Kreek MJ. Association of polymorphisms in the melanocortin receptor type 2 (MC2R, ACTH receptor) gene with heroin addiction. Neuroscience Letters. 435: 234-9. PMID 18359160 DOI: 10.1016/J.Neulet.2008.02.042  0.302
2008 Glass MJ, Lane DA, Colago EE, Chan J, Schlussman SD, Zhou Y, Kreek MJ, Pickel VM. Chronic administration of morphine is associated with a decrease in surface AMPA GluR1 receptor subunit in dopamine D1 receptor expressing neurons in the shell and non-D1 receptor expressing neurons in the core of the rat nucleus accumbens. Experimental Neurology. 210: 750-61. PMID 18294632 DOI: 10.1016/J.Expneurol.2008.01.012  0.391
2008 Oosterhuis BE, LaForge KS, Proudnikov D, Ho A, Nielsen DA, Gianotti R, Barral S, Gordon D, Leal SM, Ott J, Kreek MJ. Catechol-O-methyltransferase (COMT) gene variants: possible association of the Val158Met variant with opiate addiction in Hispanic women. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 793-8. PMID 18270997 DOI: 10.1002/Ajmg.B.30716  0.551
2008 Nielsen DA, Ji F, Yuferov V, Ho A, Chen A, Levran O, Ott J, Kreek MJ. Genotype patterns that contribute to increased risk for or protection from developing heroin addiction. Molecular Psychiatry. 13: 417-28. PMID 18195715 DOI: 10.1038/Sj.Mp.4002147  0.588
2008 Nielsen DA, Barral S, Proudnikov D, Kellogg S, Ho A, Ott J, Kreek MJ. TPH2 and TPH1: association of variants and interactions with heroin addiction. Behavior Genetics. 38: 133-50. PMID 18181017 DOI: 10.1007/S10519-007-9187-7  0.556
2008 Butelman ER, Reed B, Chait BT, Mandau M, Yuferov V, Kreek MJ. Limited effects of beta-endorphin compared to loperamide or fentanyl in a neuroendocrine biomarker assay in non-human primates. Psychoneuroendocrinology. 33: 292-304. PMID 18171605 DOI: 10.1016/J.Psyneuen.2007.11.011  0.342
2008 Zhou Y, Leri F, Cummins E, Hoeschele M, Kreek MJ. Involvement of arginine vasopressin and V1b receptor in heroin withdrawal and heroin seeking precipitated by stress and by heroin. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 226-36. PMID 17443128 DOI: 10.1038/Sj.Npp.1301419  0.382
2008 Nielsen D, Yuferov V, Hamon S, Jackson C, Ott J, Kreek MJ. 55. Increased DNA methylation in the promoter region of the μ-opioid receptor gene (ORPM1) in lymphocytes of Caucasian methadone maintained former heroin addicts Brain Behavior and Immunity. 22: 16-17. DOI: 10.1016/J.Bbi.2008.04.056  0.605
2007 Kroslak T, Laforge KS, Gianotti RJ, Ho A, Nielsen DA, Kreek MJ. The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor. Journal of Neurochemistry. 103: 77-87. PMID 17877633 DOI: 10.1111/J.1471-4159.2007.04738.X  0.596
2007 Koob G, Kreek MJ. Stress, dysregulation of drug reward pathways, and the transition to drug dependence. The American Journal of Psychiatry. 164: 1149-59. PMID 17671276 DOI: 10.1176/Appi.Ajp.2007.05030503  0.383
2007 Bailey A, Gianotti R, Ho A, Kreek MJ. Downregulation of kappa-opioid receptors in basolateral amygdala and septum of rats withdrawn for 14 days from an escalating dose "binge" cocaine administration paradigm. Synapse (New York, N.Y.). 61: 820-6. PMID 17621646 DOI: 10.1002/syn.20436  0.354
2007 Williams TJ, LaForge KS, Gordon D, Bart G, Kellogg S, Ott J, Kreek MJ. Prodynorphin gene promoter repeat associated with cocaine/alcohol codependence. Addiction Biology. 12: 496-502. PMID 17559549 DOI: 10.1111/J.1369-1600.2007.00069.X  0.364
2007 Kreek MJ, LaForge KS. Stress responsivity, addiction, and a functional variant of the human mu-opioid receptor gene. Molecular Interventions. 7: 74-8. PMID 17468387 DOI: 10.1124/mi.7.2.7  0.329
2007 Nielsen DA, Leidner M, Haynes C, Krauthammer M, Kreek MJ. The BiolAD-DB system : an informatics system for clinical and genetic data. Molecular Diagnosis & Therapy. 11: 15-9. PMID 17286447 DOI: 10.1007/Bf03256219  0.494
2007 Zhou Y, Adomako-Mensah J, Yuferov V, Ho A, Zhang J, Xu M, Kreek MJ. Effects of acute "binge" cocaine on mRNA levels of mu opioid receptor and neuropeptides in dopamine D1 or D3 receptor knockout mice. Synapse (New York, N.Y.). 61: 50-9. PMID 17068774 DOI: 10.1002/Syn.20340  0.41
2007 Butelman ER, Mandau M, Tidgewell K, Prisinzano TE, Yuferov V, Kreek MJ. Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans. The Journal of Pharmacology and Experimental Therapeutics. 320: 300-6. PMID 17060493 DOI: 10.1124/Jpet.106.112417  0.4
2007 Kuzmin A, Kreek MJ, Bakalkin G, Liljequist S. The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 902-10. PMID 16880770 DOI: 10.1038/Sj.Npp.1301169  0.363
2006 Zhou Y, Bendor J, Hofmann L, Randesi M, Ho A, Kreek MJ. Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal. The Journal of Endocrinology. 191: 137-45. PMID 17065397 DOI: 10.1677/Joe.1.06960  0.43
2006 Kellogg S, Melia D, Khuri E, Lin A, Ho A, Kreek MJ. Adolescent and young adult heroin patients: drug use and success in methadone maintenance treatment. Journal of Addictive Diseases. 25: 15-25. PMID 16956865 DOI: 10.1300/J069V25N03_03  0.341
2006 Bart G, LaForge KS, Borg L, Lilly C, Ho A, Kreek MJ. Altered levels of basal cortisol in healthy subjects with a 118G allele in exon 1 of the Mu opioid receptor gene. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2313-7. PMID 16794569 DOI: 10.1038/Sj.Npp.1301128  0.388
2006 Aouizerate B, Ho A, Schluger JH, Perret G, Borg L, Le Moal M, Piazza PV, Kreek MJ. Glucocorticoid negative feedback in methadone-maintained former heroin addicts with ongoing cocaine dependence: dose-response to dexamethasone suppression. Addiction Biology. 11: 84-96. PMID 16759341 DOI: 10.1111/J.1369-1600.2006.00006.X  0.434
2006 Peles E, Kreek MJ, Kellogg S, Adelson M. High methadone dose significantly reduces cocaine use in methadone maintenance treatment (MMT) patients. Journal of Addictive Diseases. 25: 43-50. PMID 16597572 DOI: 10.1300/J069V25N01_07  0.427
2006 Zhang Y, Svenningsson P, Picetti R, Schlussman SD, Nairn AC, Ho A, Greengard P, Kreek MJ. Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2645-51. PMID 16525043 DOI: 10.1523/Jneurosci.3923-05.2006  0.4
2006 Sinha R, Garcia M, Paliwal P, Kreek MJ, Rounsaville BJ. Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes. Archives of General Psychiatry. 63: 324-31. PMID 16520439 DOI: 10.1001/Archpsyc.63.3.324  0.429
2006 Fox HC, Garcia M, Kemp K, Milivojevic V, Kreek MJ, Sinha R. Gender differences in cardiovascular and corticoadrenal response to stress and drug cues in cocaine dependent individuals. Psychopharmacology. 185: 348-57. PMID 16514523 DOI: 10.1007/S00213-005-0303-1  0.421
2006 Leri F, Zhou Y, Goddard B, Cummins E, Kreek MJ. Effects of high-dose methadone maintenance on cocaine place conditioning, cocaine self-administration, and mu-opioid receptor mRNA expression in the rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1462-74. PMID 16237390 DOI: 10.1038/Sj.Npp.1300927  0.47
2005 Kreek MJ, Nielsen DA, Butelman ER, LaForge KS. Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction. Nature Neuroscience. 8: 1450-7. PMID 16251987 DOI: 10.1038/Nn1583  0.555
2005 Schlussman SD, Zhou Y, Bailey A, Ho A, Kreek MJ. Steady-dose and escalating-dose "binge" administration of cocaine alter expression of behavioral stereotypy and striatal preprodynorphin mRNA levels in rats. Brain Research Bulletin. 67: 169-75. PMID 16144651 DOI: 10.1016/J.Brainresbull.2005.04.018  0.395
2005 Schmidt MD, Schmidt MS, Butelman ER, Harding WW, Tidgewell K, Murry DJ, Kreek MJ, Prisinzano TE. Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates. Synapse (New York, N.Y.). 58: 208-10. PMID 16138318 DOI: 10.1002/Syn.20191  0.304
2005 Zhou Y, Bendor JT, Yuferov V, Schlussman SD, Ho A, Kreek MJ. Amygdalar vasopressin mRNA increases in acute cocaine withdrawal: evidence for opioid receptor modulation. Neuroscience. 134: 1391-7. PMID 16039786 DOI: 10.1016/J.Neuroscience.2005.05.032  0.502
2005 Glass MJ, Kruzich PJ, Colago EE, Kreek MJ, Pickel VM. Increased AMPA GluR1 receptor subunit labeling on the plasma membrane of dendrites in the basolateral amygdala of rats self-administering morphine. Synapse (New York, N.Y.). 58: 1-12. PMID 16037950 DOI: 10.1002/Syn.20176  0.399
2005 Bart G, Schluger JH, Borg L, Ho A, Bidlack JM, Kreek MJ. Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 2254-62. PMID 15988468 DOI: 10.1038/Sj.Npp.1300811  0.454
2005 Fox HC, Talih M, Malison R, Anderson GM, Kreek MJ, Sinha R. Frequency of recent cocaine and alcohol use affects drug craving and associated responses to stress and drug-related cues. Psychoneuroendocrinology. 30: 880-91. PMID 15975729 DOI: 10.1016/J.Psyneuen.2005.05.002  0.407
2005 Bailey A, Yuferov V, Bendor J, Schlussman SD, Zhou Y, Ho A, Kreek MJ. Immediate withdrawal from chronic "binge" cocaine administration increases mu-opioid receptor mRNA levels in rat frontal cortex. Brain Research. Molecular Brain Research. 137: 258-62. PMID 15950784 DOI: 10.1016/J.Molbrainres.2005.02.017  0.471
2005 Bailey A, Gianotti R, Ho A, Kreek MJ. Persistent upregulation of mu-opioid, but not adenosine, receptors in brains of long-term withdrawn escalating dose "binge" cocaine-treated rats. Synapse (New York, N.Y.). 57: 160-6. PMID 15945065 DOI: 10.1002/Syn.20168  0.479
2005 Yuferov V, Nielsen D, Butelman E, Kreek MJ. Microarray studies of psychostimulant-induced changes in gene expression. Addiction Biology. 10: 101-18. PMID 15849024 DOI: 10.1080/13556210412331308976  0.603
2005 Kreek MJ, Bart G, Lilly C, LaForge KS, Nielsen DA. Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments. Pharmacological Reviews. 57: 1-26. PMID 15734726 DOI: 10.1124/Pr.57.1.1  0.677
2005 Zhang Y, Butelman ER, Schlussman SD, Ho A, Kreek MJ. Effects of the plant-derived hallucinogen salvinorin A on basal dopamine levels in the caudate putamen and in a conditioned place aversion assay in mice: agonist actions at kappa opioid receptors. Psychopharmacology. 179: 551-8. PMID 15682306 DOI: 10.1007/S00213-004-2087-0  0.417
2005 Bart G, Kreek MJ, Ott J, LaForge KS, Proudnikov D, Pollak L, Heilig M. Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 417-22. PMID 15525999 DOI: 10.1038/Sj.Npp.1300598  0.359
2005 Kreek MJ. Impact of bidirectional translational research on treatment of addiction Clinical Neuroscience Research. 5: 123-139. DOI: 10.1016/J.Cnr.2005.08.008  0.303
2004 Yuferov V, Fussell D, LaForge KS, Nielsen DA, Gordon D, Ho A, Leal SM, Ott J, Kreek MJ. Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. Pharmacogenetics. 14: 793-804. PMID 15608558 DOI: 10.1097/00008571-200412000-00002  0.623
2004 Zhou Y, Spangler R, Yuferov VP, Schlussmann SD, Ho A, Kreek MJ. Effects of selective D1- or D2-like dopamine receptor antagonists with acute "binge" pattern cocaine on corticotropin-releasing hormone and proopiomelanocortin mRNA levels in the hypothalamus. Brain Research. Molecular Brain Research. 130: 61-7. PMID 15519677 DOI: 10.1016/J.Molbrainres.2004.07.008  0.438
2004 Kreek MJ, Schlussman SD, Bart G, Laforge KS, Butelman ER. Evolving perspectives on neurobiological research on the addictions: celebration of the 30th anniversary of NIDA. Neuropharmacology. 47: 324-44. PMID 15464148 DOI: 10.1016/J.Neuropharm.2004.07.024  0.413
2004 Glass MJ, Kruzich PJ, Kreek MJ, Pickel VM. Decreased plasma membrane targeting of NMDA-NR1 receptor subunit in dendrites of medial nucleus tractus solitarius neurons in rats self-administering morphine. Synapse (New York, N.Y.). 53: 191-201. PMID 15266550 DOI: 10.1002/Syn.20049  0.328
2004 Butelman ER, Harris TJ, Kreek MJ. Antiallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates. The Journal of Pharmacology and Experimental Therapeutics. 311: 155-63. PMID 15152028 DOI: 10.1124/Jpet.104.068411  0.332
2004 Mantsch JR, Yuferov V, Mathieu-Kia AM, Ho A, Kreek MJ. Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. Psychopharmacology. 175: 26-36. PMID 15042275 DOI: 10.1007/S00213-004-1778-X  0.718
2004 Bart G, Heilig M, LaForge KS, Pollak L, Leal SM, Ott J, Kreek MJ. Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden. Molecular Psychiatry. 9: 547-9. PMID 15037869 DOI: 10.1038/Sj.Mp.4001504  0.408
2004 Kreek MJ, Nielsen DA, LaForge KS. Genes associated with addiction: alcoholism, opiate, and cocaine addiction. Neuromolecular Medicine. 5: 85-108. PMID 15001815 DOI: 10.1385/Nmm:5:1:085  0.616
2004 Zhang Y, Butelman ER, Schlussman SD, Ho A, Kreek MJ. Effect of the kappa opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. Psychopharmacology. 173: 146-52. PMID 14712342 DOI: 10.1007/S00213-003-1716-3  0.461
2004 Zhang Y, Butelman ER, Schlussman SD, Ho A, Kreek MJ. Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. Psychopharmacology. 172: 422-9. PMID 14712335 DOI: 10.1007/S00213-003-1688-3  0.481
2004 Butelman ER, Ball JW, Kreek MJ. Peripheral selectivity and apparent efficacy of dynorphins: comparison to non-peptidic kappa-opioid agonists in rhesus monkeys. Psychoneuroendocrinology. 29: 307-26. PMID 14644063 DOI: 10.1016/S0306-4530(03)00030-1  0.373
2004 Butelman ER, Harris TJ, Kreek MJ. The plant-derived hallucinogen, salvinorin A, produces kappa-opioid agonist-like discriminative effects in rhesus monkeys. Psychopharmacology. 172: 220-4. PMID 14586540 DOI: 10.1007/S00213-003-1638-0  0.376
2003 Zhang Y, Schlussman SD, Ho A, Kreek MJ. Effect of chronic "binge cocaine" on basal levels and cocaine-induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice. Synapse (New York, N.Y.). 50: 191-9. PMID 14515336 DOI: 10.1002/Syn.10251  0.434
2003 Mantsch JR, Yuferov V, Mathieu-Kia AM, Ho A, Kreek MJ. Neuroendocrine alterations in a high-dose, extended-access rat self-administration model of escalating cocaine use. Psychoneuroendocrinology. 28: 836-62. PMID 12892653 DOI: 10.1016/S0306-4530(02)00088-4  0.718
2003 Sinha R, Talih M, Malison R, Cooney N, Anderson GM, Kreek MJ. Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states. Psychopharmacology. 170: 62-72. PMID 12845411 DOI: 10.1007/S00213-003-1525-8  0.422
2003 Butelman ER, Ball JW, Harris TJ, Kreek MJ. Topical capsaicin-induced allodynia in unanesthetized primates: pharmacological modulation. The Journal of Pharmacology and Experimental Therapeutics. 306: 1106-14. PMID 12829725 DOI: 10.1124/Jpet.103.052381  0.336
2003 Zhou Y, Spangler R, Ho A, Kreek MJ. Increased CRH mRNA levels in the rat amygdala during short-term withdrawal from chronic 'binge' cocaine. Brain Research. Molecular Brain Research. 114: 73-9. PMID 12782395 DOI: 10.1016/S0169-328X(03)00139-6  0.44
2003 Schlussman SD, Zhang Y, Kane S, Stewart CL, Ho A, Kreek MJ. Locomotion, stereotypy, and dopamine D1 receptors after chronic "binge" cocaine in C57BL/6J and 129/J mice. Pharmacology, Biochemistry, and Behavior. 75: 123-31. PMID 12759120 DOI: 10.1016/S0091-3057(03)00067-4  0.434
2003 Bart G, Borg L, Schluger JH, Green M, Ho A, Kreek MJ. Suppressed prolactin response to dynorphin A1-13 in methadone-maintained versus control subjects. The Journal of Pharmacology and Experimental Therapeutics. 306: 581-7. PMID 12730354 DOI: 10.1124/Jpet.103.050682  0.372
2003 Schluger JH, Bart G, Green M, Ho A, Kreek MJ. Corticotropin-releasing factor testing reveals a dose-dependent difference in methadone maintained vs control subjects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 985-94. PMID 12700714 DOI: 10.1038/Sj.Npp.1300156  0.336
2003 Yuferov V, Kroslak T, Laforge KS, Zhou Y, Ho A, Kreek MJ. Differential gene expression in the rat caudate putamen after "binge" cocaine administration: advantage of triplicate microarray analysis. Synapse (New York, N.Y.). 48: 157-69. PMID 12687634 DOI: 10.1002/Syn.10198  0.421
2003 Proudnikov D, Yuferov V, LaForge KS, Ho A, Kreek MJ. Quantification of multiple mRNA levels in rat brain regions using real time optical PCR Molecular Brain Research. 112: 182-185. PMID 12670717 DOI: 10.1016/S0169-328X(03)00056-1  0.318
2003 Kellogg SH, McHugh PF, Bell K, Schluger JH, Schluger RP, LaForge KS, Ho A, Kreek MJ. The Kreek-McHugh-Schluger-Kellogg scale: a new, rapid method for quantifying substance abuse and its possible applications. Drug and Alcohol Dependence. 69: 137-50. PMID 12609695 DOI: 10.1016/S0376-8716(02)00308-3  0.36
2003 Kakko J, Svanborg KD, Kreek MJ, Heilig M. 1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial. Lancet. 361: 662-8. PMID 12606177 DOI: 10.1016/S0140-6736(03)12600-1  0.322
2003 Proudnikov D, Yuferov V, Zhou Y, LaForge KS, Ho A, Kreek MJ. Optimizing primer--probe design for fluorescent PCR. Journal of Neuroscience Methods. 123: 31-45. PMID 12581847 DOI: 10.1016/S0165-0270(02)00325-4  0.306
2003 Zhou Y, Spangler R, Schlussman SD, Ho A, Kreek MJ. Alterations in hypothalamic-pituitary-adrenal axis activity and in levels of proopiomelanocortin and corticotropin-releasing hormone-receptor 1 mRNAs in the pituitary and hypothalamus of the rat during chronic 'binge' cocaine and withdrawal. Brain Research. 964: 187-99. PMID 12576179 DOI: 10.1016/S0006-8993(02)03929-X  0.433
2003 Kruzich PJ, Chen AC, Unterwald EM, Kreek MJ. Subject-regulated dosing alters morphine self-administration behavior and morphine-stimulated [35S]GTPgammaS binding. Synapse (New York, N.Y.). 47: 243-9. PMID 12539196 DOI: 10.1002/Syn.10173  0.373
2003 LaForge KS, Yuferov V, Zhou Y, Ho A, Nyberg F, Kreek MJ. Binge cocaine differentially alters preproenkephalin mRNA levels in guinea pig brain Brain Research Bulletin. 59: 353-357. PMID 12507685 DOI: 10.1016/S0361-9230(02)00927-9  0.409
2002 Butelman ER, Ball JW, Kreek MJ. Comparison of the discriminative and neuroendocrine effects of centrally penetrating kappa-opioid agonists in rhesus monkeys. Psychopharmacology. 164: 115-20. PMID 12373425 DOI: 10.1007/S00213-002-1195-Y  0.388
2002 Kreek MJ, Vocci FJ. History and current status of opioid maintenance treatments: blending conference session. Journal of Substance Abuse Treatment. 23: 93-105. PMID 12220607 DOI: 10.1016/S0740-5472(02)00259-3  0.393
2002 Kreek MJ, LaForge KS, Butelman E. Pharmacotherapy of addictions. Nature Reviews. Drug Discovery. 1: 710-26. PMID 12209151 DOI: 10.1038/Nrd897  0.366
2002 Zhang Y, Mantsch JR, Schlussman SD, Ho A, Kreek MJ. Conditioned place preference after single doses or "binge" cocaine in C57BL/6J and 129/J mice. Pharmacology, Biochemistry, and Behavior. 73: 655-62. PMID 12151041 DOI: 10.1016/S0091-3057(02)00859-6  0.71
2002 Zhou Y, Spangler R, Schlussman SD, Yuferov VP, Sora I, Ho A, Uhl GR, Kreek MJ. Effects of acute "binge" cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin-releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice. Synapse (New York, N.Y.). 45: 220-9. PMID 12125043 DOI: 10.1002/Syn.10101  0.464
2002 Borg L, Ho A, Wells A, Joseph H, Appel P, Moody D, Kreek MJ. The use of levo-alpha-acetylmethadol (LAAM) in methadone patients who have not achieved heroin abstinence. Journal of Addictive Diseases. 21: 13-22. PMID 12094997 DOI: 10.1300/J069V21N03_02  0.396
2002 Schlussman SD, Nyberg F, Kreek MJ. The effects of drug abuse on the stress responsive hypothalamic-pituitary-adrenal axis and the dopaminergic and endogenous opioid systems. Acta Psychiatrica Scandinavica. Supplementum. 121-4. PMID 12072142 DOI: 10.1034/J.1600-0447.106.S412.26.X  0.398
2002 King AC, Schluger J, Gunduz M, Borg L, Perret G, Ho A, Kreek MJ. Hypothalamic-pituitary-adrenocortical (HPA) axis response and biotransformation of oral naltrexone: preliminary examination of relationship to family history of alcoholism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 778-88. PMID 12007748 DOI: 10.1016/S0893-133X(01)00416-X  0.332
2002 Chen AC, LaForge KS, Ho A, McHugh PF, Kellogg S, Bell K, Schluger RP, Leal SM, Kreek MJ. Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse. American Journal of Medical Genetics. 114: 429-35. PMID 11992566 DOI: 10.1002/Ajmg.10362  0.452
2002 Kreek MJ, LaForge KS, Butelman E. Correction: Pharmacotherapy of addictions Nature Reviews Drug Discovery. 1: 926-926. DOI: 10.1038/Nrd968  0.445
2002 Kreek MJ, Borg L, Zhou Y, Schluger J. Relationships between Endocrine Functions and Substance Abuse Syndromes: Heroin and Related Short-Acting Opiates in Addiction Contrasted with Methadone and Other Long-Acting Opioid Agonists Used in Pharmacotherapy of Addiction Hormones, Brain and Behavior. 781-830. DOI: 10.1016/B978-012532104-4/50108-6  0.404
2001 Zhang Y, Schlussman SD, Ho A, Kreek MJ. Effect of acute binge cocaine on levels of extracellular dopamine in the caudate putamen and nucleus accumbens in male C57BL/6J and 129/J mice. Brain Research. 923: 172-7. PMID 11743985 DOI: 10.1016/S0006-8993(01)03032-3  0.383
2001 Zhou Y, Spangler R, Ho A, Kreek MJ. Hypothalamic CRH mRNA levels are differentially modulated by repeated ‘binge’ cocaine with or without D1 dopamine receptor blockade Molecular Brain Research. 94: 112-118. PMID 11597771 DOI: 10.1016/S0169-328X(01)00223-6  0.429
2001 Zhou Y, Unterwald EM, Ho A, LaForge KS, Yuferov VP, Kreuter J, Sirianni MJ, Allen RG, Kreek MJ. Ablation of pituitary pro-opiomelanocortin (POMC) cells produces alterations in hypothalamic POMC mRNA levels and midbrain mu opioid receptor binding in a conditional transgenic mouse model. Journal of Neuroendocrinology. 13: 808-17. PMID 11578531 DOI: 10.1046/J.1365-2826.2001.00702.X  0.398
2001 Mantsch JR, Ho A, Schlussman SD, Kreek MJ. Predictable individual differences in the initiation of cocaine self-administration by rats under extended-access conditions are dose-dependent. Psychopharmacology. 157: 31-9. PMID 11512040 DOI: 10.1007/S002130100744  0.714
2001 Cigler T, LaForge KS, McHugh PF, Kapadia SU, Leal SM, Kreek MJ. Novel and previously reported single-nucleotide polymorphisms in the human 5-HT(1B) receptor gene: no association with cocaine or alcohol abuse or dependence. American Journal of Medical Genetics. 105: 489-97. PMID 11496363 DOI: 10.1002/Ajmg.1473  0.396
2001 Kreek MJ. Drug addictions. Molecular and cellular endpoints. Annals of the New York Academy of Sciences. 937: 27-49. PMID 11458539 DOI: 10.1111/J.1749-6632.2001.Tb03557.X  0.339
2001 Butelman ER, Kreek MJ. kappa-Opioid receptor agonist-induced prolactin release in primates is blocked by dopamine D(2)-like receptor agonists. European Journal of Pharmacology. 423: 243-9. PMID 11448491 DOI: 10.1016/S0014-2999(01)01121-9  0.402
2001 Yuferov V, Zhou Y, LaForge KS, Spangler R, Ho A, Kreek MJ. Elevation of guinea pig brain preprodynorphin mRNA expression and hypothalamic-pituitary-adrenal axis activity by "binge" pattern cocaine administration. Brain Research Bulletin. 55: 65-70. PMID 11427339 DOI: 10.1016/S0361-9230(01)00496-8  0.449
2001 Unterwald EM, Kreek MJ, Cuntapay M. The frequency of cocaine administration impacts cocaine-induced receptor alterations. Brain Research. 900: 103-9. PMID 11325352 DOI: 10.1016/S0006-8993(01)02269-7  0.472
2001 Schluger JH, Borg L, Ho A, Kreek MJ. Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 568-75. PMID 11282257 DOI: 10.1016/S0893-133X(00)00222-0  0.434
2001 Mathieu-Kia AM, Fan LQ, Kreek MJ, Simon EJ, Hiller JM. Mu-, delta- and kappa-opioid receptor populations are differentially altered in distinct areas of postmortem brains of Alzheimer's disease patients. Brain Research. 893: 121-34. PMID 11223000 DOI: 10.1016/S0006-8993(00)03302-3  0.388
2001 Jacobsen LK, Giedd JN, Kreek MJ, Gottschalk C, Kosten TR. Quantitative medial temporal lobe brain morphology and hypothalamic-pituitary-adrenal axis function in cocaine dependence: a preliminary report. Drug and Alcohol Dependence. 62: 49-56. PMID 11173167 DOI: 10.1016/S0376-8716(00)00159-9  0.412
2000 Quiñones-Jenab V, Perrotti LI, Mc Monagle J, Ho A, Kreek MJ. Ovarian hormone replacement affects cocaine-induced behaviors in ovariectomized female rats. Pharmacology, Biochemistry, and Behavior. 67: 417-22. PMID 11164068 DOI: 10.1016/S0091-3057(00)00381-6  0.422
2000 LaForge KS, Yuferov V, Kreek MJ. Opioid receptor and peptide gene polymorphisms: potential implications for addictions. European Journal of Pharmacology. 410: 249-268. PMID 11134674 DOI: 10.1016/S0014-2999(00)00819-0  0.437
2000 Kling MA, Carson RE, Borg L, Zametkin A, Matochik JA, Schluger J, Herscovitch P, Rice KC, Ho A, Eckelman WC, Kreek MJ. Opioid receptor imaging with positron emission tomography and [(18)F]cyclofoxy in long-term, methadone-treated former heroin addicts. The Journal of Pharmacology and Experimental Therapeutics. 295: 1070-6. PMID 11082442  0.312
2000 LaForge KS, Shick V, Spangler R, Proudnikov D, Yuferov V, Lysov Y, Mirzabekov A, Kreek MJ. Detection of single nucleotide polymorphisms of the human mu opioid receptor gene by hybridization or single nucleotide extension on custom oligonucleotide gelpad microchips: potential in studies of addiction. American Journal of Medical Genetics. 96: 604-15. PMID 11054767 DOI: 10.1002/1096-8628(20001009)96:5<604::Aid-Ajmg5>3.0.Co;2-F  0.373
2000 Zhou Y, Franck J, Spangler R, Maggos CE, Ho A, Kreek MJ. Reduced hypothalamic POMC and anterior pituitary CRF1 receptor mRNA levels after acute, but not chronic, daily "binge" intragastric alcohol administration. Alcoholism, Clinical and Experimental Research. 24: 1575-82. PMID 11045867 DOI: 10.1111/J.1530-0277.2000.Tb04577.X  0.306
2000 Kreek MJ. Methadone-related opioid agonist pharmacotherapy for heroin addiction. History, recent molecular and neurochemical research and future in mainstream medicine. Annals of the New York Academy of Sciences. 909: 186-216. PMID 10911931 DOI: 10.1111/J.1749-6632.2000.Tb06683.X  0.467
2000 Quiñones-Jenab V, Perrotti LI, Ho A, Jenab S, Schlussman SD, Franck J, Kreek MJ. Cocaine affects progesterone plasma levels in female rats. Pharmacology, Biochemistry, and Behavior. 66: 449-53. PMID 10880704 DOI: 10.1016/S0091-3057(00)00213-6  0.416
2000 Mantsch JR, Schlussman SD, Ho A, Kreek MJ. Effects of cocaine self-administration on plasma corticosterone and prolactin in rats. The Journal of Pharmacology and Experimental Therapeutics. 294: 239-47. PMID 10871318  0.688
2000 Schlussman SD, Zhou Y, Johansson P, Kiuru A, Ho A, Nyberg F, Kreek MJ. Effects of the androgenic anabolic steroid, nandrolone decanoate, on adrenocorticotropin hormone, corticosterone and proopiomelanocortin, corticotropin releasing factor (CRF) and CRF receptor1 mRNA levels in the hypothalamus, pituitary and amygdala of the rat. Neuroscience Letters. 284: 190-4. PMID 10773431 DOI: 10.1016/S0304-3940(00)01016-8  0.318
2000 Quiñones-Jenab V, Krey LC, Schlussman SD, Ho A, Kreek MJ. Chronic 'binge' pattern cocaine alters the neuroendocrine profile of pregnant rats. Neuroscience Letters. 282: 120-2. PMID 10713411 DOI: 10.1016/S0304-3940(00)00869-7  0.405
2000 Farren CK, O’Malley S, Tilton R, Kreek MJ. 460. Opioid abnormalities in alcoholism: naltrexone induced responses Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00730-7  0.347
1999 Borg L, Broe DM, Ho A, Kreek MJ. Cocaine abuse sharply reduced in an effective methadone maintenance program. Journal of Addictive Diseases. 18: 63-75. PMID 10631964 DOI: 10.1300/J069V18N04_06  0.472
1999 Butelman ER, Harris TJ, Kreek MJ. Apparent efficacy of κ-opioid receptor ligands on serum prolactin levels in rhesus monkeys European Journal of Pharmacology. 383: 305-309. PMID 10594324 DOI: 10.1016/S0014-2999(99)00640-8  0.378
1999 Butelman ER, Harris TJ, Kreek MJ. Effects of E-2078, a stable dynorphin A(1-8) analog, on sedation and serum prolactin levels in rhesus monkeys. Psychopharmacology. 147: 73-80. PMID 10591871 DOI: 10.1007/S002130051144  0.376
1999 Zhou Y, Spangler R, Maggos CE, Wang XM, Han JS, Ho A, Kreek MJ. Hypothalamic-pituitary-adrenal activity and pro-opiomelanocortin mRNA levels in the hypothalamus and pituitary of the rat are differentially modulated by acute intermittent morphine with or without water restriction stress. The Journal of Endocrinology. 163: 261-7. PMID 10556776 DOI: 10.1677/Joe.0.1630261  0.35
1999 Zhou Y, Schlussman SD, Ho A, Spangler R, Fienberg AA, Greengard P, Kreek MJ. Effects of chronic 'Binge' cocaine administration on plasma ACTH and corticosterone levels in mice deficient in DARPP-32. Neuroendocrinology. 70: 196-9. PMID 10516482 DOI: 10.1159/000054476  0.444
1999 Rosen MI, Kosten TR, Kreek MJ. The effects of naltrexone maintenance on the response to yohimbine in healthy volunteers. Biological Psychiatry. 45: 1636-45. PMID 10376126 DOI: 10.1016/S0006-3223(98)00259-5  0.345
1999 Quiñones-Jenab V, Ho A, Schlussman SD, Franck J, Kreek MJ. Estrous cycle differences in cocaine-induced stereotypic and locomotor behaviors in Fischer rats. Behavioural Brain Research. 101: 15-20. PMID 10342395 DOI: 10.1016/S0166-4328(98)00073-4  0.425
1999 Butelman ER, Vivian JA, Yu J, Kreek MJ, Woods JH. Systemic effects of E-2078, a stabilized dynorphin A(1-8) analog, in rhesus monkeys. Psychopharmacology. 143: 190-6. PMID 10326782 DOI: 10.1007/S002130050935  0.364
1999 Yuferov V, Zhou Y, Spangler R, Maggos CE, Ho A, Kreek MJ. Acute "binge" cocaine increases mu-opioid receptor mRNA levels in areas of the rat mesolimbic mesocortical dopamine system. Brain Research Bulletin. 48: 109-12. PMID 10210176 DOI: 10.1016/S0361-9230(98)00155-5  0.497
1999 King AC, Ho A, Schluger J, Borg L, Kreek MJ. Acute subjective effects of dynorphin A(1-13) infusion in normal healthy subjects. Drug and Alcohol Dependence. 54: 87-90. PMID 10101621 DOI: 10.1016/S0376-8716(98)00150-1  0.338
1999 Wang XM, Zhou Y, Spangler R, Ho A, Han JS, Kreek MJ. Acute intermittent morphine increases preprodynorphin and kappa opioid receptor mRNA levels in the rat brain. Brain Research. Molecular Brain Research. 66: 184-7. PMID 10095091 DOI: 10.1016/S0169-328X(99)00021-2  0.399
1999 Kreek MJ, Schluger J, Borg L, Gunduz M, Ho A. Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: gender differences and implications for modulation of dopaminergic tone in the treatment of addictions. The Journal of Pharmacology and Experimental Therapeutics. 288: 260-9. PMID 9862779  0.381
1999 Portenoy RK, Caraceni A, Cherny NI, Goldblum R, Ingham J, Inturrisi CE, Johnson JH, Lapin J, Tiseo PJ, Kreek MJ. Dynorphin A(1-13) analgesia in opioid-treated patients with chronic pain. A controlled pilot study Clinical Drug Investigation. 17: 33-42. DOI: 10.2165/00044011-199917010-00004  0.351
1998 Sarnyai Z, Dhabhar FS, McEwen BS, Kreek MJ. Neuroendocrine-related effects of long-term, 'binge' cocaine administration: diminished individual differences in stress-induced corticosterone response. Neuroendocrinology. 68: 334-44. PMID 9822801 DOI: 10.1159/000054382  0.422
1998 Schluger JH, Ho A, Borg L, Porter M, Maniar S, Gunduz M, Perret G, King A, Kreek MJ. Nalmefene causes greater hypothalamic-pituitary-adrenal axis activation than naloxone in normal volunteers: implications for the treatment of alcoholism. Alcoholism, Clinical and Experimental Research. 22: 1430-6. PMID 9802524 DOI: 10.1111/J.1530-0277.1998.Tb03931.X  0.43
1998 Sarnyai Z, McKittrick CR, McEwen BS, Kreek MJ. Selective regulation of dopamine transporter binding in the shell of the nucleus accumbens by adrenalectomy and corticosterone-replacement. Synapse (New York, N.Y.). 30: 334-7. PMID 9776137 DOI: 10.1002/(Sici)1098-2396(199811)30:3<334::Aid-Syn11>3.0.Co;2-#  0.326
1998 Perret G, Schluger JH, Unterwald EM, Kreuter J, Ho A, Kreek MJ. Downregulation of 5-HT1A receptors in rat hypothalamus and dentate gyrus after "binge" pattern cocaine administration. Synapse (New York, N.Y.). 30: 166-71. PMID 9723786 DOI: 10.1002/(Sici)1098-2396(199810)30:2<166::Aid-Syn6>3.0.Co;2-A  0.442
1998 Zhou Y, Yuferov VP, Spangler R, Maggos CE, Ho A, Kreek MJ. Effects of memantine alone and with acute 'binge' cocaine on hypothalamic-pituitary-adrenal activity in the rat. European Journal of Pharmacology. 352: 65-71. PMID 9718269 DOI: 10.1016/S0014-2999(98)00332-X  0.433
1998 Kreek MJ, Koob GF. Drug dependence: stress and dysregulation of brain reward pathways. Drug and Alcohol Dependence. 51: 23-47. PMID 9716928 DOI: 10.1016/S0376-8716(98)00064-7  0.333
1998 Bond C, LaForge KS, Tian M, Melia D, Zhang S, Borg L, Gong J, Schluger J, Strong JA, Leal SM, Tischfield JA, Kreek MJ, Yu L. Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proceedings of the National Academy of Sciences of the United States of America. 95: 9608-13. PMID 9689128 DOI: 10.1073/Pnas.95.16.9608  0.437
1998 Specker S, Wananukul W, Hatsukami D, Nolin K, Hooke L, Kreek MJ, Pentel PR. Effects of dynorphin A(1-13) on opiate withdrawal in humans. Psychopharmacology. 137: 326-32. PMID 9676891 DOI: 10.1007/S002130050626  0.321
1998 Maggos CE, Tsukada H, Kakiuchi T, Nishiyama S, Myers JE, Kreuter J, Schlussman SD, Unterwald EM, Ho A, Kreek MJ. Sustained withdrawal allows normalization of in vivo [11C]N-methylspiperone dopamine D2 receptor binding after chronic binge cocaine: a positron emission tomography study in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 146-53. PMID 9629568 DOI: 10.1016/S0893-133X(98)00009-8  0.388
1997 Unterwald EM, Tsukada H, Kakiuchi T, Kosugi T, Nishiyama S, Kreek MJ. Use of positron emission tomography to measure the effects of nalmefene on D1 and D2 dopamine receptors in rat brain. Brain Research. 775: 183-8. PMID 9439841 DOI: 10.1016/S0006-8993(97)00931-1  0.337
1997 Quiñones-Jenab V, Batel P, Schlussman SD, Ho A, Kreek MJ. Cocaine impairs maternal nest building in pregnant rats. Pharmacology, Biochemistry, and Behavior. 58: 1009-13. PMID 9408207 DOI: 10.1016/S0091-3057(97)00311-0  0.411
1997 Lucas LR, Schlussman SD, Ho A, McEwen BS, Kreek MJ. Novelty-induced locomoter activity in Long-Evans rats pre- and post-chronic 'binge'-pattern cocaine treatment. Neuroscience Letters. 237: 25-8. PMID 9406871 DOI: 10.1016/S0304-3940(97)00799-4  0.415
1997 Bergasa NV, Mohajer B, Maisonneuve IM, Ho A, Maidment NT, Olive F, Gunduz M, Kreek MJ. Basal total opioid peptide release in the striatum of rats with cholestasis from bile duct resection: a study by the use of in vivo microdialysis. Life Sciences. 61: 1169-75. PMID 9315507 DOI: 10.1016/S0024-3205(97)00658-9  0.362
1997 King AC, Volpicelli JR, Gunduz M, O'Brien CP, Kreek MJ. Naltrexone biotransformation and incidence of subjective side effects: a preliminary study. Alcoholism, Clinical and Experimental Research. 21: 906-9. PMID 9267542 DOI: 10.1111/J.1530-0277.1997.Tb03856.X  0.337
1997 Kreek MJ. Opiate and cocaine addictions: challenge for pharmacotherapies. Pharmacology, Biochemistry, and Behavior. 57: 551-69. PMID 9218280 DOI: 10.1016/S0091-3057(96)00440-6  0.42
1997 Spangler R, Zhou Y, Schlussman SD, Ho A, Kreek MJ. Behavioral stereotypies induced by "binge' cocaine administration are independent of drug-induced increases in corticosterone levels. Behavioural Brain Research. 86: 201-4. PMID 9134155 DOI: 10.1016/S0166-4328(96)02257-7  0.449
1997 Maggos CE, Spangler R, Zhou Y, Schlussman SD, Ho A, Kreek MJ. Quantitation of dopamine transporter mRNA in the rat brain: mapping, effects of "binge" cocaine administration and withdrawal. Synapse (New York, N.Y.). 26: 55-61. PMID 9097405 DOI: 10.1002/(Sici)1098-2396(199705)26:1<55::Aid-Syn6>3.0.Co;2-D  0.378
1997 Culpepper-Morgan JA, Kreek MJ. Hypothalamic-pituitary-adrenal axis hypersensitivity to naloxone in opioid dependence: a case of naloxone-induced withdrawal. Metabolism: Clinical and Experimental. 46: 130-4. PMID 9030816 DOI: 10.1016/S0026-0495(97)90289-4  0.399
1997 Spangler R, Zhou Y, Maggos CE, Schlussman SD, Ho A, Kreek MJ. Prodynorphin, proenkephalin and kappa opioid receptor mRNA responses to acute "binge" cocaine. Brain Research. Molecular Brain Research. 44: 139-42. PMID 9030708 DOI: 10.1016/S0169-328X(96)00249-5  0.442
1997 Kreek MJ. Clinical Update of Opioid Agonist and Partial Agonist Medications for the Maintenance Treatment of Opioid Addiction Seminars in Neuroscience. 9: 140-157. DOI: 10.1006/Smns.1997.0114  0.432
1996 Kreek MJ. Opiates, opioids and addiction. Molecular Psychiatry. 1: 232-54. PMID 9118348  0.311
1996 Unterwald EM, Fillmore J, Kreek MJ. Chronic repeated cocaine administration increases dopamine D1 receptor-mediated signal transduction. European Journal of Pharmacology. 318: 31-5. PMID 9007509 DOI: 10.1016/S0014-2999(96)00841-2  0.429
1996 Peters JE, Chou JZ, Ho A, Reid K, Borg L, Kreek MJ. Simplified quantitation of urinary benzoylecgonine in cocaine addiction research and for related pharmacotherapeutic trials. Addiction (Abingdon, England). 91: 1687-97. PMID 8972926 DOI: 10.1046/J.1360-0443.1996.911116879.X  0.408
1996 Zhou Y, Spangler R, Maggos CE, LaForge KS, Ho A, Kreek MJ. Steady-state methadone in rats does not change mRNA levels of corticotropin-releasing factor, its pituitary receptor or proopiomelanocortin. European Journal of Pharmacology. 315: 31-5. PMID 8960861 DOI: 10.1016/S0014-2999(96)00672-3  0.381
1996 Kreek MJ. Opioid receptors: some perspectives from early studies of their role in normal physiology, stress responsivity, and in specific addictive diseases. Neurochemical Research. 21: 1469-88. PMID 8947936 DOI: 10.1007/Bf02532387  0.47
1996 Kreek MJ. Cocaine, dopamine and the endogenous opioid system. Journal of Addictive Diseases. 15: 73-96. PMID 8943583 DOI: 10.1300/J069V15N04_05  0.458
1996 Spangler R, Zhou Y, Maggos CE, Zlobin A, Ho A, Kreek MJ. Dopamine antagonist and "binge' cocaine effects on rat opioid and dopamine transporter mRNAs. Neuroreport. 7: 2196-200. PMID 8930988 DOI: 10.1097/00001756-199609020-00028  0.441
1996 Tsukada H, Kreuter J, Maggos CE, Unterwald EM, Kakiuchi T, Nishiyama S, Futatsubashi M, Kreek MJ. Effects of binge pattern cocaine administration on dopamine D1 and D2 receptors in the rat brain: an in vivo study using positron emission tomography. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7670-7. PMID 8922423 DOI: 10.1523/Jneurosci.16-23-07670.1996  0.394
1996 Zhou Y, Spangler R, LaForge KS, Maggos CE, Ho A, Kreek MJ. Corticotropin-releasing factor and type 1 corticotropin-releasing factor receptor messenger RNAs in rat brain and pituitary during "binge"-pattern cocaine administration and chronic withdrawal. The Journal of Pharmacology and Experimental Therapeutics. 279: 351-8. PMID 8859013  0.318
1996 Spangler R, Ho A, Zhou Y, Maggos CE, Yuferov V, Kreek MJ. Regulation of kappa opioid receptor mRNA in the rat brain by "binge' pattern cocaine administration and correlation with preprodynorphin mRNA. Brain Research. Molecular Brain Research. 38: 71-6. PMID 8737669 DOI: 10.1016/0169-328X(95)00319-N  0.44
1996 Donovan DM, Miner LL, Sharpe L, Cho HJ, Takemura M, Unterwald E, Nyberg F, Kreek MJ, Uhl GR. Transgenic mice: preproenkephalin and the mu opiate receptor. Annals of the New York Academy of Sciences. 780: 19-28. PMID 8602733 DOI: 10.1111/J.1749-6632.1996.Tb15108.X  0.328
1995 Unterwald EM, Rubenfeld JM, Imai Y, Wang JB, Uhl GR, Kreek MJ. Chronic opioid antagonist administration upregulates mu opioid receptor binding without altering mu opioid receptor mRNA levels. Brain Research. Molecular Brain Research. 33: 351-5. PMID 8750897 DOI: 10.1016/0169-328X(95)00143-G  0.437
1995 Borg L, Ho A, Peters JE, Kreek MJ. Availability of reliable serum methadone determination for management of symptomatic patients. Journal of Addictive Diseases. 14: 83-96. PMID 8555281 DOI: 10.1300/J069V14N03_06  0.343
1995 Culpepper-Morgan JA, Holt PR, LaRoche D, Kreek MJ. Orally administered opioid antagonists reverse both mu and kappa opioid agonist delay of gastrointestinal transit in the guinea pig Life Sciences. 56: 1187-1192. PMID 7475895 DOI: 10.1016/0024-3205(95)00057-D  0.392
1994 Lai Z, Zhai Q, Yukhananov R, Larsson C, Roos P, Kreek MJ, Nyberg F. Effects of morphine on prolactin receptors in the rat brain Febs Letters. 338: 207-211. PMID 8307182 DOI: 10.1016/0014-5793(94)80366-8  0.319
1994 Unterwald EM, Rubenfeld JM, Kreek MJ. Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors. Neuroreport. 5: 1613-6. PMID 7819531 DOI: 10.1097/00001756-199408150-00018  0.499
1994 Zhou Y, Spangler R, LaForge KS, Kreek MJ. Attenuation of the hypothalamic-pituitary-adrenal response to chronic “binge” pattern cocaine administration corresponds to decreased CRH mRNA in rat hypothalamus Regulatory Peptides. 54: 345-346. DOI: 10.1016/0167-0115(94)90530-4  0.423
1994 Unterwald EM, Rubenfeld JM, Spangler R, Imai Y, Wang JB, Uhl GR, Kreek MJ. Mu opioid receptor mRNA levels following chronic naltrexone administration Regulatory Peptides. 54: 307-308. DOI: 10.1016/0167-0115(94)90512-6  0.418
1994 Spangler R, Zhou Y, Unterwald E, Yuferov V, Ho A, Kreek MJ. Kappa opioid receptor mRNA levels in the rat brain: Effects of dopamine antagonists and cocaine Regulatory Peptides. 54: 283-284. DOI: 10.1016/0167-0115(94)90500-2  0.468
1994 Kreek MJ. Pharmacotherapy of opioid dependence: Rationale and update Regulatory Peptides. 53. DOI: 10.1016/0167-0115(94)90336-0  0.397
1994 Unterwald E, Kreek MJ. Kappa and delta opioid receptor densities following chronic repeated cocaine administration Regulatory Peptides. 53: S225-S226. DOI: 10.1016/0167-0115(94)90322-0  0.453
1993 Unterwald EM, Cox BM, Kreek MJ, Cote TE, Izenwasser S. Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity. Synapse (New York, N.Y.). 15: 33-8. PMID 8310423 DOI: 10.1002/Syn.890150104  0.497
1993 Spangler R, Unterwald EM, Kreek MJ. 'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. Brain Research. Molecular Brain Research. 19: 323-7. PMID 7694032 DOI: 10.1016/0169-328X(93)90133-A  0.42
1993 Culpepper-Morgan JA, Inturisi CE, Portenoy RK, Foley K, Houde RW, Marsh F, Kreek MJ. Treatment of Opioid-Induced Constipation with Oral Naloxone: A Pilot Study Survey of Anesthesiology. 37: 239. DOI: 10.1097/00132586-199308000-00063  0.376
1992 Culpepper‐Morgan JA, Inturrisi CE, Portenoy RK, Foley K, Houde RW, Marsh F, Kreek MJ. Treatment of opioid‐induced constipation with oral naloxone: A pilot study Clinical Pharmacology &Amp; Therapeutics. 52: 90-95. PMID 1623695 DOI: 10.1038/Clpt.1992.106  0.363
1992 Kosten TR, Morgan C, Kreek MJ. Beta endorphin levels during heroin, methadone, buprenorphine, and naloxone challenges: preliminary findings. Biological Psychiatry. 32: 523-8. PMID 1445968 DOI: 10.1016/0006-3223(92)90220-T  0.386
1992 Unterwald EM, Horne-King J, Kreek MJ. Chronic cocaine alters brain mu opioid receptors. Brain Research. 584: 314-8. PMID 1325249 DOI: 10.1016/0006-8993(92)90912-S  0.505
1992 Branch AD, Unterwald EM, Lee SE, Kreek MJ. Quantitation of preproenkephalin mRNA levels in brain regions from male Fischer rats following chronic cocaine treatment using a recently developed solution hybridization assay. Brain Research. Molecular Brain Research. 14: 231-8. PMID 1279343 DOI: 10.1016/0169-328X(92)90178-E  0.355
1991 Tabasco-Minguillan J, Novick DM, Kreek MJ. Liver function tests in non-parenteral cocaine users Nida Research Monograph. 105: 372. PMID 1876045 DOI: 10.1016/0376-8716(90)90124-W  0.403
1990 Kennedy JA, Hartman N, Sbriglio R, Khuri E, Kreek MJ. Metyrapone-induced withdrawal symptoms. Addiction. 85: 1133-1140. PMID 2224193 DOI: 10.1111/J.1360-0443.1990.Tb03438.X  0.358
1987 Novick DM, Senie RT, Kreek MJ, Yancovitz SR. Clinical and demographic features of patients admitted to a new chemical dependency program in New York City Drug and Alcohol Dependence. 20: 271-278. PMID 3436259 DOI: 10.1016/0376-8716(87)90037-8  0.334
1986 Kosten TR, Kreek MJ, Ragunath J, Kleber HD. Cortisol levels during chronic naltrexone maintenance treatment in ex-opiate addicts. Biological Psychiatry. 21: 217-20. PMID 3947698 DOI: 10.1016/0006-3223(86)90150-2  0.371
1986 Novick DM, Stenger RJ, Gelb AM, Most J, Yancovitz SR, Kreek MJ. Chronic liver disease in abusers of alcohol and parenteral drugs: A report of 204 consecutive biopsy-proven cases Alcoholism: Clinical and Experimental Research. 10: 500-505. PMID 3541673 DOI: 10.1111/J.1530-0277.1986.Tb05131.X  0.321
1985 Novick DM, Enlow RW, Gelb AM, Stenger RJ, Fotino M, Winter JW, Yancovitz SR, Schoenberg MD, Kreek MJ. Hepatic cirrhosis in young adults: Association with adolescent onset of alcohol and parenteral heroin abuse Gut. 26: 8-13. PMID 3855296 DOI: 10.1136/Gut.26.1.8  0.301
1984 Kreek MJ. Opioid interactions with alcohol. Advances in Alcohol and Substance Abuse. 3: 35-46. PMID 6391108 DOI: 10.1300/J251V03N04_04  0.421
1983 Hartman N, Kreek MJ, Ross A, Khuri E, Millman RB, Rodriguez R. Alcohol use in youthful methadone-maintained former heroin addicts: Liver impairment and treatment outcome Alcoholism: Clinical and Experimental Research. 7: 316-320. PMID 6353983 DOI: 10.1111/J.1530-0277.1983.Tb05469.X  0.304
1983 Ragavan VV, Wardlaw SL, Kreek MJ, Frantz AG. Effect of chronic naltrexone and methadone administration on brain immunoreactive beta-endorphin in the rat. Neuroendocrinology. 37: 266-8. PMID 6314167 DOI: 10.1159/000123556  0.302
1983 Kreek M, Hahn E, Schaefer R, Fishman J. Naloxone, A Specific Opioid Antagonist, Reverses Chronic Idiopathic Constipation The Lancet. 321: 261-262. PMID 6130292 DOI: 10.1016/S0140-6736(83)91684-7  0.41
1982 Kreek MJ, Hartman N. Chronic Use Of Opioids And Antipsychotic Drugs: Side Effects, Effects On Endogenous Opioids, And Toxicity * Annals of the New York Academy of Sciences. 398: 151-172. PMID 6130734 DOI: 10.1111/J.1749-6632.1982.Tb39489.X  0.411
1982 Kreek MJ. Opioid Disposition and Effects During Chronic Exposure in the Perinatal Period in Man Advances in Alcohol and Substance Abuse. 1: 21-53. DOI: 10.1300/J251V01N03_03  0.434
1981 Tong TG, Pond SM, Kreek MJ, Jaffery NF, Benowitz NL. Phenytoin-Induced Methadone Withdrawal Annals of Internal Medicine. 94: 349-351. PMID 7224382 DOI: 10.7326/0003-4819-94-3-349  0.317
1981 Kreek MJ. Metabolic Interactions Between Opiates And Alcohol Annals of the New York Academy of Sciences. 362: 36-49. PMID 6942711 DOI: 10.1111/J.1749-6632.1981.Tb12789.X  0.302
1980 Tong TG, Benowitz NL, Kreek MJ. Methadone—Disulfiram Interaction During Methadone Maintenance The Journal of Clinical Pharmacology. 20: 506-513. PMID 7430415 DOI: 10.1002/J.1552-4604.1980.Tb02543.X  0.331
1976 Kreek MJ, Garfield JW, Gutjahr CL, Giusti LM. Rifampin-induced methadone withdrawal. The New England Journal of Medicine. 294: 1104-6. PMID 1256526 DOI: 10.1056/Nejm197605132942008  0.303
1973 Dole VP, Kreek MJ. Methadone plasma level: sustained by a reservoir of drug in tissue. Proceedings of the National Academy of Sciences of the United States of America. 70: 10. PMID 4509643 DOI: 10.1073/Pnas.70.1.10  0.3
Low-probability matches (unlikely to be authored by this person)
1998 Ghodse AH, Kreek M. Resurgence of abuse of amphetamine-type stimulants Current Opinion in Psychiatry. 11: 245-247. DOI: 10.1097/00001504-199805000-00001  0.299
2019 Zhou Y, Leri F, Low MJ, Kreek MJ. Sex differences in the effect of bupropion and naltrexone combination on alcohol drinking in mice. Pharmacology, Biochemistry, and Behavior. PMID 30991059 DOI: 10.1016/J.Pbb.2019.04.004  0.299
2019 Butelman ER, McElroy BD, Prisinzano TE, Kreek MJ. Impact of Pharmacological Manipulation of the -Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice. The Journal of Pharmacology and Experimental Therapeutics. 370: 1-8. PMID 30975792 DOI: 10.1124/jpet.119.256354  0.298
1989 Novick DM, Trigg HL, Des Jarlais DC, Friedman SR, Vlahov D, Kreek MJ. Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (HIV) epidemic in New York City Journal of Medical Virology. 29: 181-185. PMID 2614398 DOI: 10.1002/Jmv.1890290307  0.298
2013 Zhou Y, Colombo G, Niikura K, Carai MA, Femenía T, García-Gutiérrez MS, Manzanares J, Ho A, Gessa GL, Kreek MJ. Voluntary alcohol drinking enhances proopiomelanocortin gene expression in nucleus accumbens shell and hypothalamus of Sardinian alcohol-preferring rats. Alcoholism, Clinical and Experimental Research. 37: E131-40. PMID 22724395 DOI: 10.1111/J.1530-0277.2012.01867.X  0.298
2000 Perret G, Déglon JJ, Kreek MJ, Ho A, La Harpe R. Lethal methadone intoxications in Geneva, Switzerland, from 1994 to 1998. Addiction (Abingdon, England). 95: 1647-53. PMID 11219368 DOI: 10.1046/J.1360-0443.2000.951116475.X  0.298
2004 Kreek MJ, Jones R, Kleber HD, Kosten T, O'Brien C. NIDA's commitment to tackling drug abuse. Nature. 430: 965. PMID 15329694 DOI: 10.1038/430965B  0.297
1997 Berman Y, Devi L, Spangler R, Kreek MJ, Carr KD. Chronic food restriction and streptozotocin-induced diabetes differentially alter prodynorphin mRNA levels in rat brain regions. Brain Research. Molecular Brain Research. 46: 25-30. PMID 9191075 DOI: 10.1016/S0169-328X(96)00175-1  0.297
2020 Zhang Y, Collins D, Butelman ER, Blendy JA, Kreek MJ. Relapse-like behavior in a mouse model of the OPRM1 (mu-opioid receptor) A118G polymorphism: Examination with intravenous oxycodone self-administration. Neuropharmacology. 108351. PMID 33031806 DOI: 10.1016/j.neuropharm.2020.108351  0.296
1998 Peluso J, LaForge KS, Matthes HW, Kreek MJ, Kieffer BL, Gavériaux-Ruff C. Distribution of nociceptin/orphanin FQ receptor transcript in human central nervous system and immune cells. Journal of Neuroimmunology. 81: 184-92. PMID 9521621 DOI: 10.1016/S0165-5728(97)00178-1  0.296
2011 Zhou Y, Colombo G, Carai MA, Ho A, Gessa GL, Kreek MJ. Involvement of arginine vasopressin and V1b receptor in alcohol drinking in Sardinian alcohol-preferring rats. Alcoholism, Clinical and Experimental Research. 35: 1876-83. PMID 21575018 DOI: 10.1111/J.1530-0277.2011.01532.X  0.295
1984 Kaufmann CA, Kreek MJ, Karoum F, Chuang L. Depression during methadone withdrawal: No role for β-phenylethylamine Drug and Alcohol Dependence. 13: 21-29. PMID 6734421 DOI: 10.1016/0376-8716(84)90029-2  0.295
2012 Levran O, Awolesi O, Shen PH, Adelson M, Kreek MJ. Estimating ancestral proportions in a multi-ethnic US sample: implications for studies of admixed populations. Human Genomics. 6: 2. PMID 23244743 DOI: 10.1186/1479-7364-6-2  0.294
1981 Ziring BS, Kreek MJ, Brown LT. Methadone disposition following oral versus parenteral dose administration in rats during chronic treatment Drug and Alcohol Dependence. 7: 311-318. PMID 7274003 DOI: 10.1016/0376-8716(81)90047-8  0.294
2003 Schlussman SD, Zhang Y, Yuferov V, LaForge KS, Ho A, Kreek MJ. Acute 'binge' cocaine administration elevates dynorphin mRNA in the caudate putamen of C57BL/6J but not 129/J mice. Brain Research. 974: 249-53. PMID 12742644 DOI: 10.1016/S0006-8993(03)02561-7  0.294
2016 Zhou Y, Rubinstein M, Low MJ, Kreek MJ. Hypothalamic-specific proopiomelanocortin-deficiency reduces alcohol drinking in male and female mice. Genes, Brain, and Behavior. PMID 27870313 DOI: 10.1111/Gbb.12362  0.293
2018 Randesi M, van den Brink W, Levran O, Yuferov V, Blanken P, van Ree JM, Ott J, Kreek MJ. Dopamine gene variants in opioid addiction: comparison of dependent patients, nondependent users and healthy controls. Pharmacogenomics. 19: 95-104. PMID 29210332 DOI: 10.2217/Pgs-2017-0134  0.293
2018 Reed B, Butelman ER, Fry RS, Kimani R, Kreek MJ. Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and without Cocaine Dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 43: 928. PMID 29422497 DOI: 10.1038/npp.2017.245  0.293
2000 Stimmel B, Kreek MJ. Neurobiology of addictive behaviors and its relationship to methadone maintenance. The Mount Sinai Journal of Medicine, New York. 67: 375-80. PMID 11064487  0.292
1976 Rothschild MA, Kreek MJ, Oratz M, Schreiber SS, Mongelli JG. The Stimulation of Albumin Synthesis by Methadone Gastroenterology. 71: 214-220. DOI: 10.1016/S0016-5085(76)80190-4  0.292
2014 Niikura K, Zhang Y, Ho A, Kreek M. Different sensitivity for oxycodone-induced conditioned place preference and sensitization of locomotor activity in adolescent and adult mice Drug and Alcohol Dependence. 140: e162. DOI: 10.1016/J.Drugalcdep.2014.02.457  0.291
1973 Kreek MJ. Medical safety and side effects of methadone in tolerant individuals. Jama. 223: 665-668. DOI: 10.1001/Jama.1973.03220060039009  0.287
1998 Schlussman SD, Ho A, Zhou Y, Curtis AE, Kreek MJ. Effects of "binge" pattern cocaine on stereotypy and locomotor activity in C57BL/6J and 129/J mice. Pharmacology, Biochemistry, and Behavior. 60: 593-9. PMID 9632245 DOI: 10.1016/S0091-3057(98)00047-1  0.286
1983 Preston DM, Barnes PRH, Fielding J, O'Malley K, Kreek M, Schaefer R, Hahn E, Fishman J. Naloxone In Chronic Constipation The Lancet. 321: 758. DOI: 10.1016/S0140-6736(83)92039-1  0.285
1990 Kreek MJ, Des Jarlais DC, Trepo CL, Novick DM, Abdul-Quader A, Raghunath J. Contrasting prevalence of delta hepatitis markers in parenteral drug abusers with and without AIDS Journal of Infectious Diseases. 162: 538-541. PMID 2373877 DOI: 10.1093/Infdis/162.2.538  0.285
1999 Farren CK, O'Malley S, Grebski G, Maniar S, Porter M, Kreek MJ. Variable dose naltrexone-induced hypothalamic-pituitary-adrenal stimulation in abstinent alcoholics: a preliminary study. Alcoholism, Clinical and Experimental Research. 23: 502-8. PMID 10195825 DOI: 10.1111/J.1530-0277.1999.Tb04144.X  0.284
1981 Kreek MJ, Rothschild MA, Oratz M, Mongelli J, Handley AC. Acute effects of ethanol on hepatic uptake and distribution of narcotics in the isolated perfused rabbit liver. Hepatology. 1: 419-423. PMID 7308987 DOI: 10.1002/Hep.1840010509  0.284
2016 Zhou Y, Huang T, Lee F, Kreek MJ. Involvement of Endocannabinoids in Alcohol "Binge" Drinking: Studies of Mice with Human Fatty Acid Amide Hydrolase Genetic Variation and After CB1 Receptor Antagonists. Alcoholism, Clinical and Experimental Research. PMID 26857901 DOI: 10.1111/Acer.12989  0.284
2001 Butelman ER, Ko MC, Traynor JR, Vivian JA, Kreek MJ, Woods JH. GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 298: 1049-59. PMID 11504802  0.283
2012 Proudnikov D, Randesi M, Levran O, Crystal H, Dorn M, Ott J, Ho A, Kreek MJ. Association of polymorphisms of the mu opioid receptor gene with the severity of HIV infection and response to HIV treatment. The Journal of Infectious Diseases. 205: 1745-56. PMID 22457278 DOI: 10.1093/Infdis/Jis264  0.282
2011 Ray B, Jackson C, Ducat E, Ho A, Hamon S, Kreek MJ. Effect of ethnicity, gender and drug use history on achieving high rates of affirmative informed consent for genetics research: impact of sharing with a national repository. Journal of Medical Ethics. 37: 374-9. PMID 21266386 DOI: 10.1136/Jme.2010.037671  0.281
2013 Zhou Y, Colombo G, Gessa GL, Kreek MJ. Effects of voluntary alcohol drinking on corticotropin-releasing factor and preprodynorphin mRNA levels in the central amygdala of Sardinian alcohol-preferring rats. Neuroscience Letters. 554: 110-4. PMID 24021806 DOI: 10.1016/J.Neulet.2013.08.071  0.281
2002 O'Malley SS, Krishnan-Sarin S, Farren C, Sinha R, Kreek MJ. Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis. Psychopharmacology. 160: 19-29. PMID 11862370 DOI: 10.1007/S002130100919  0.281
2020 Zhou Y, Liang Y, Kreek MJ. mTORC1 pathway is involved in the kappa opioid receptor activation-induced increase in excessive alcohol drinking in mice. Pharmacology, Biochemistry, and Behavior. 172954. PMID 32470351 DOI: 10.1016/J.Pbb.2020.172954  0.281
2006 Proudnikov D, LaForge KS, Hofflich H, Levenstien M, Gordon D, Barral S, Ott J, Kreek MJ. Association analysis of polymorphisms in serotonin 1B receptor (HTR1B) gene with heroin addiction: a comparison of molecular and statistically estimated haplotypes. Pharmacogenetics and Genomics. 16: 25-36. PMID 16344719 DOI: 10.1097/01.Fpc.0000182782.87932.D6  0.279
2017 Zhang Y, Liang Y, Randesi M, Levran O, Yuferov V, Kreek MJ. RNA-seq analysis: Differential transcriptome in the dorsal and ventral striatum in male C57BL/6J mice after chronic oxycodone self-administration Drug and Alcohol Dependence. 171. DOI: 10.1016/J.Drugalcdep.2016.08.612  0.279
2013 Proudnikov D, Randesi M, Levran O, Yuferov V, Crystal H, Ho A, Ott J, Kreek MJ. Polymorphisms of the kappa opioid receptor and prodynorphin genes: HIV risk and HIV natural history. Journal of Acquired Immune Deficiency Syndromes (1999). 63: 17-26. PMID 23392455 DOI: 10.1097/Qai.0B013E318285Cd0C  0.279
2014 Yuferov V, Brownstein AJ, Ducat E, Randesi M, Ho A, Kreek MJ. Association of the prodynorphin gene promoter repeat polymorphism with basal prolactin level in normal human male volunteers Drug and Alcohol Dependence. 140. DOI: 10.1016/J.Drugalcdep.2014.02.687  0.277
2021 Hedrick SL, Luo D, Kaska S, Niloy KK, Jackson K, Sarma R, Horn J, Baynard C, Leggas M, Butelman ER, Kreek MJ, Prisinzano TE. Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent. Journal of Biomedical Science. 28: 62. PMID 34503531 DOI: 10.1186/s12929-021-00758-y  0.277
1986 Kosten TR, Kreek MJ, Ragunath J, Kleber HD. A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addicts. Life Sciences. 39: 55-9. PMID 2941636 DOI: 10.1016/0024-3205(86)90437-6  0.277
2013 Adelson M, Wilson HW, Celeste VY, Linzy S, Kreek MJ, Peles E. Methadone maintenance treatment experience in Macao--prospective follow-up for initial 4.5 years. Journal of Psychoactive Drugs. 45: 313-21. PMID 24377170 DOI: 10.1080/02791072.2013.825032  0.275
2023 Zhang Y, Butelman ER, Kreek MJ. Effect of prenatal and early post-natal oxycodone exposure on the reinforcing and antinociceptive effects of oxycodone in adult C57BL/6 J mice. Psychopharmacology. PMID 38086926 DOI: 10.1007/s00213-023-06493-6  0.274
2015 Altschuler JH, Niikura K, Butelman E, Kreek MJ, Zhang Y. Adolescent oxycodone self administration alters subsequent antinociceptive effect of oxycodone in C57BL/6J mice in adulthood Drug and Alcohol Dependence. 156. DOI: 10.1016/J.Drugalcdep.2015.07.935  0.273
1983 Kreek MJ, Bencsath FA, Fanizza A, Field FH. Effects of liver disease on fecal excretion of methadone and its unconjugated metabolites in maintenance patients. Quantitation by direct probe chemical ionization mass spectrometry Biomedical Mass Spectrometry. 10: 544-549. PMID 6652228 DOI: 10.1002/Bms.1200101003  0.272
2013 Proudnikov D, Yuferov V, Randesi M, Kreek MJ. Genetics of Opioid Addiction Biological Research On Addiction. 509-521. DOI: 10.1016/B978-0-12-398335-0.00050-9  0.272
1972 Kreek MJ, Dodes L, Kane S, Knobler J, Martin R. Long-Term Methadone Maintenance Therapy: Effects on Liver Function Annals of Internal Medicine. 77: 598-602. PMID 4629927 DOI: 10.7326/0003-4819-77-4-598  0.272
1996 Zhou Y, Spangler R, LaForge KS, Maggos CE, Ho A, Kreek MJ. Modulation Of Crf-R1 Mrna In Rat Anterior Pituitary By Dexamethasone : Correlation With Pomc Mrna Peptides. 17: 435-441. PMID 8735970 DOI: 10.1016/0196-9781(96)00014-9  0.271
2009 Kreek MJ, Talal AH, Piccolo P. Treating chronic hepatitis C in recovering opiate addicts: yes, we can. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 41: 308-10. PMID 19233749 DOI: 10.1016/J.Dld.2009.01.003  0.27
2005 Kellogg SH, Kreek MJ. Gradualism, identity, reinforcements, and change International Journal of Drug Policy. 16: 369-375. DOI: 10.1016/J.Drugpo.2005.08.001  0.27
1983 Hahn EF, Lahita R, Kreek MJ, Duma C, Inturrisi CE. Naloxone radioimmunoassay: an improved antiserum Journal of Pharmacy and Pharmacology. 35: 833-836. PMID 6141253 DOI: 10.1111/J.2042-7158.1983.Tb02910.X  0.269
1988 Novick DM, Des Jarlais DC, Kreek MJ, Spira TJ, Friedman SR, Gelb AM, Stenger RJ, Schable CA, Kalyanaraman VS. Specificity of antibody tests for human immunodeficiency virus in alcohol and parenteral drug abusers with chronic liver disease. Alcoholism, Clinical and Experimental Research. 12: 687-90. PMID 3067617 DOI: 10.1111/J.1530-0277.1988.Tb00266.X  0.269
2001 LaForge KS, Yuferov V, Kreek MJ. Corrigendum to “Opioid receptor and peptide gene polymorphisms: potential implications for addictions” [Eur. J. Pharmacol. 410 (2001) 249–268] European Journal of Pharmacology. 426: 145. DOI: 10.1016/S0014-2999(01)01160-8  0.269
2015 Deutsch-Feldman M, Zhang Y, Buonora M, Brownstein A, Niikura K, Ho A, Ott J, Kreek MJ. Self-administration of oxycodone by adolescent and adult mice differentially affects hypothalamic mitochondrial metabolism gene expression Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.185  0.268
1977 Hachey DL, Kreek MJ, Mattson DH. Quantitative Analysis of Methadone in Biological Fluids Using Deuterium-Labeled Methadone and GLC-Chemical-Ionization Mass Spectrometry Journal of Pharmaceutical Sciences. 66: 1579-1582. PMID 915734 DOI: 10.1002/Jps.2600661120  0.267
1985 Novick DM, Kreek MJ, Arns PA, Lau LL, Yancovitz SR, Gelb AM. Effect of severe alcoholic liver disease on the disposition of methadone in maintenance patients Alcoholism: Clinical and Experimental Research. 9: 349-354. PMID 3901806 DOI: 10.1111/J.1530-0277.1985.Tb05558.X  0.267
1980 Kreek MJ, Bencsath FA, Field FH. Effects of liver disease on urinary excretion of methadone and metabolites in maintenance patients: quantitation by direct probe chemical ionization mass spectrometry Biomedical Mass Spectrometry. 7: 385-395. PMID 7470591 DOI: 10.1002/Bms.1200070906  0.267
1984 Kreek M, Ragunath J, Plevy S, Hamer D, Schneider B, Hartman N. ACTH, cortisol and β-endorphin response to metyrapone testing during chronic methadone maintenance treatment in humans Neuropeptides. 5: 277-278. PMID 6099512 DOI: 10.1016/0143-4179(84)90081-7  0.267
1993 Novick DM, Richman BL, Friedman JM, Friedman JE, Fried C, Wilson JP, Townley A, Kreek MJ. The medical status of methadone maintenance patients in treatment for 11-18 years Drug and Alcohol Dependence. 33: 235-245. PMID 8261888 DOI: 10.1016/0376-8716(93)90110-C  0.267
2021 Butelman ER, Baynard C, McElroy BD, Prisinzano TE, Kreek MJ. Profile of a short-acting κ-antagonist, LY2795050, on self-grooming behaviors, forced swim test and locomotor activity: sex comparison in mice. Journal of Psychopharmacology (Oxford, England). 269881121996883. PMID 33769112 DOI: 10.1177/0269881121996883  0.267
1994 Ochshorn‐Adelson M, Bodner G, Toraker P, Albeck H, Ho A, Kreek MJ. Effects of ethanol on human natural killer cell activity: in vitro and acute, low-dose in vivo studies. Alcoholism: Clinical and Experimental Research. 18: 1361-1367. PMID 7695031 DOI: 10.1111/J.1530-0277.1994.Tb01437.X  0.266
2006 Galarneau DW, Teres JJ, Leon AC, Melia D, Lilly C, Kellogg S, Khuri E, Kreek MJ. Antidepressant treatment patterns in a novel methadone maintenance clinic targeting young adults an observational study. Journal of Addictive Diseases. 25: 47-52. PMID 16785219 DOI: 10.1300/J069V25N02_07  0.265
2014 Butelman ER, Picetti R, Reed B, Yuferov V, Kreek MJ. Addictions Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders. 570-584. DOI: 10.1016/B978-0-12-398270-4.00035-5  0.264
1980 Kreek MJ, Schecter AJ, Gutjahr CL, Hecht M. Methadone use in patients with chronic renal disease. Drug and Alcohol Dependence. 5: 197-205. PMID 6986247 DOI: 10.1016/0376-8716(80)90180-5  0.263
2015 Collins DT, Kreek MJ, Zhang Y. Oxycodone-induced conditioned place preference and locomotor activity in adult female C57BL/6J mice Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.145  0.262
2015 Rahm SP, Ho A, Kreek MJ, Zhang Y. Adolescent C57BL/6J mice self-administer more oxycodone than adult mice in an extended-access paradigm (4 h) Drug and Alcohol Dependence. 156. DOI: 10.1016/J.Drugalcdep.2015.07.495  0.262
1978 Cushman P, Kreek MJ, Gordis E. Ethanol and methadone in man: A possible drug interaction Drug and Alcohol Dependence. 3: 35-42. DOI: 10.1016/0376-8716(78)90033-9  0.261
1989 Des Jarlais DC, Friedman SR, Novick DM, Sotheran JL, Thomas P, Yancovitz SR, Mildvan D, Weber J, Kreek MJ, Maslansky R, Bartelme S, Spira T, Marmor M. HIV-1 Infection Among Intravenous Drug Users in Manhattan, New York City, From 1977 Through 1987 Jama: the Journal of the American Medical Association. 261: 1008-1012. PMID 2915408 DOI: 10.1001/Jama.1989.03420070058030  0.261
1968 Kreek M, Sleisenger M. Reduction Of Serum-Unconjugated-Bilirubin With Phenobarbitone In Adult Congenital Non-Hæmolytic Unconjugated Hyperbilirubinæmia The Lancet. 292: 73-78. DOI: 10.1016/S0140-6736(68)90356-5  0.26
2006 Kellogg S, Kreek MJ. On blending practice and research: the search for commonalities in substance abuse treatment. Substance Abuse. 27: 9-24. PMID 17062541 DOI: 10.1300/J465V27N01_03  0.26
2016 Levran O, Peles E, Randesi M, Correa da Rosa J, Ott J, Rotrosen J, Adelson M, Kreek MJ. Glutamatergic and GABAergic susceptibility loci for heroin and cocaine addiction in subjects of African and European ancestry. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 64: 118-23. PMID 26277529 DOI: 10.1016/J.Pnpbp.2015.08.003  0.259
1978 Kreek MJ, Oratz M, Rothschild MA. Hepatic extraction of long- and short-acting narcotics in the isolated perfused rabbit liver. Gastroenterology. 75: 88-94. DOI: 10.1016/0016-5085(78)93770-8  0.259
2006 Fox HC, Wilker EH, Kreek MJ, Sinha R. Reliability of salivary cortisol assessments in cocaine dependent individuals. Journal of Psychopharmacology (Oxford, England). 20: 650-5. PMID 16533868 DOI: 10.1177/0269881106063474  0.259
2002 Kellogg SH, Ho A, Bell K, Schluger RP, McHugh PF, McClary KA, Kreek MJ. The Personality Assessment Inventory Drug Problems Scale: a validity analysis. Journal of Personality Assessment. 79: 73-84. PMID 12227669 DOI: 10.1207/S15327752Jpa7901_05  0.259
2015 Novick DM, Salsitz EA, Joseph H, Kreek MJ. Methadone Medical Maintenance: An Early 21st-Century Perspective. Journal of Addictive Diseases. 34: 226-37. PMID 26110221 DOI: 10.1080/10550887.2015.1059225  0.258
1976 Kreek MJ, Gutjahr CL, Garfield JW, Bowen DV, Field FH. Drug interactions with methadone. Annals of the New York Academy of Sciences. 281: 350-71. PMID 798526 DOI: 10.1111/J.1749-6632.1976.Tb27945.X  0.258
2008 Kreek MJ. 119. Addiction, personality traits, stress, and AIDS: Possible role of specific gene variants and epigenetic changes Brain Behavior and Immunity. 22: 38-39. DOI: 10.1016/J.Bbi.2008.04.122  0.257
1997 Yu J, Chait BT, Toll L, Kreek MJ. Nociceptin in vitro biotransformation in human blood. Peptides. 17: 873-6. PMID 8844779 DOI: 10.1016/0196-9781(96)00079-4  0.257
1997 Kreek MJ. Goals and rationale for pharmacotherapeutic approach in treating cocaine dependence: insights from basic and clinical research. Nida Research Monograph. 175: 5-35. PMID 9467791  0.257
1969 Kreek MJ, Peterson RE, Sleisenger MH, Jeffries GH. Effects of ethinylestradiol-induced cholestasis on bile flow and biliary excretion of estradiol and estradiol glucuronide by the rat. Experimental Biology and Medicine. 131: 646-650. PMID 5787150 DOI: 10.3181/00379727-131-33944  0.256
1998 Bodner G, Ho A, Kreek MJ. Effect of endogenous cortisol levels on natural killer cell activity in healthy humans. Brain, Behavior, and Immunity. 12: 285-96. PMID 10080858 DOI: 10.1006/Brbi.1998.0533  0.256
1989 Albeck H, Woodfield S, Kreek MJ. Quantitative and pharmacokinetic analysis of naloxone in plasma using high-performance liquid chromatography with electrochemical detection and solid-phase extraction. Journal of Chromatography B: Biomedical Sciences and Applications. 488: 435-445. PMID 2745633 DOI: 10.1016/S0378-4347(00)82967-9  0.256
1998 Mason BJ, Kocsis JH, Melia D, Khuri ET, Sweeney J, Wells A, Borg L, Millman RB, Kreek MJ. Psychiatric comorbidity in methadone maintained patients. Journal of Addictive Diseases. 17: 75-89. PMID 9789161 DOI: 10.1300/J069V17N03_07  0.256
1999 Butelman ER, Harris TJ, Perez A, Kreek MJ. Effects of systemically administered dynorphin A(1-17) in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 290: 678-86. PMID 10411578  0.255
2005 Yuferov V, Bart G, Kreek MJ. Clock reset for alcoholism. Nature Medicine. 11: 23-4. PMID 15635440 DOI: 10.1038/Nm0105-23  0.254
2014 Yuferov V, Butelman ER, Ho A, Morgello S, Kreek MJ. Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects. Journal of Neuroinflammation. 11: 5. PMID 24405578 DOI: 10.1186/1742-2094-11-5  0.254
2018 Zhou Y, Kreek MJ. Involvement of activated brain stress responsive systems in excessive and "relapse" alcohol drinking in rodent models: implications for therapeutics. The Journal of Pharmacology and Experimental Therapeutics. PMID 29669731 DOI: 10.1124/jpet.117.245621  0.253
1996 Rosen MI, McMahon TJ, Hameedi FA, Pearsall HR, Woods SW, Kreek MJ, Kosten TR. Effect of clonidine pretreatment on naloxone-precipitated opiate withdrawal. The Journal of Pharmacology and Experimental Therapeutics. 276: 1128-35. PMID 8786543  0.253
1974 Kreek MJ, Schecter A, Gutjahr CL, Bowen D, Field F, Queenan J, Merkatz I. Analyses of methadone and other drugs in maternal and neonatal body fluids: Use in evaluation of symptoms in a neonate of mother maintained on methadone American Journal of Drug and Alcohol Abuse. 1: 409-419. PMID 4619541 DOI: 10.3109/00952997409011033  0.252
2013 Yuferov V, Ho A, Morgello S, Yang Y, Ott J, Kreek MJ. Expression of ephrin receptors and ligands in postmortem brains of HIV-infected subjects with and without cognitive impairment. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 333-44. PMID 23314923 DOI: 10.1007/S11481-012-9429-1  0.252
1998 Yuferov VP, Culpepper-Morgan JA, LaForge KS, Ho A, Kreek MJ. Regional quantitation of preprodynorphin mRNA in guinea pig gastrointestinal tract. Neurochemical Research. 23: 505-11. PMID 9566584 DOI: 10.1023/A:1022426400545  0.251
2009 Lahita RG, Schaefer RA, Bradlow HL, Kreek MJ. Clues to understanding the oxidation of estradiol in humans: effects of acute infectious hepatitis, autoimmune hepatitis, and chronic liver disease. Annals of the New York Academy of Sciences. 1155: 242-51. PMID 19250211 DOI: 10.1111/J.1749-6632.2009.04359.X  0.251
1995 LaForge KS, Unterwald EM, Kreek MJ. Structure and expression of the guinea pig preproenkephalin gene: site-specific cleavage in the 3' untranslated region yields truncated mRNA transcripts in specific brain regions. Molecular and Cellular Biology. 15: 2080-9. PMID 7891703 DOI: 10.1128/Mcb.15.4.2080  0.25
2011 Sinha R, Fox HC, Hong KI, Hansen J, Tuit K, Kreek MJ. Effects of adrenal sensitivity, stress- and cue-induced craving, and anxiety on subsequent alcohol relapse and treatment outcomes. Archives of General Psychiatry. 68: 942-52. PMID 21536969 DOI: 10.1001/Archgenpsychiatry.2011.49  0.25
1978 Rubenstein RB, Kreek MJ, Mbawa N, Wolff WI, Korn R, Gutjahr CL. Human spinal fluid methadone levels Drug and Alcohol Dependence. 3: 103-106. PMID 631010 DOI: 10.1016/0376-8716(78)90022-4  0.247
2008 Kreek MJ. Role of a functional human gene polymorphism in stress responsivity and addictions. Clinical Pharmacology and Therapeutics. 83: 615-8. PMID 18323858 DOI: 10.1038/Clpt.2008.5  0.247
2017 Zhou Y, Schwartz BI, Giza J, Gross SS, Lee FS, Kreek MJ. Blockade of alcohol escalation and "relapse" drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice. Psychopharmacology. PMID 28730283 DOI: 10.1007/S00213-017-4691-9  0.247
1997 LaForge KS, Ho A, Kreek MJ. Distribution and polysome association of full-length and 3' truncated preproenkephalin mRNA in the guinea-pig brain. Brain Research. Molecular Brain Research. 46: 169-76. PMID 9191091 DOI: 10.1016/S0169-328X(96)00299-9  0.245
2015 Zhou Y, Rubinstein M, Low MJ, Kreek MJ. Alcohol drinking and related behaviors in hypothalamic-specific Pomc-deficient mice Drug and Alcohol Dependence. 146: e31-e32. DOI: 10.1016/J.Drugalcdep.2014.09.766  0.245
2014 Seip-Cammack K, Buonora M, Deutsch-Feldman M, Brownstein A, Picetti R, Kreek MJ. Handling and vehicle injections impact corticosterone but not adrenocorticotropic hormone levels in Sprague-Dawley but not Lewis rats Drug and Alcohol Dependence. 140. DOI: 10.1016/J.Drugalcdep.2014.02.559  0.243
2009 Reed B, Varon J, Chait BT, Kreek MJ. Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin. Endocrinology. 150: 2934-9. PMID 19213839 DOI: 10.1210/En.2008-1408  0.243
2013 Caspers MJ, Williams TD, Lovell KM, Lozama A, Butelman ER, Kreek MJ, Johnson M, Griffiths R, Maclean K, Prisinzano TE. LC-MS/MS quantification of salvinorin A from biological fluids. Analytical Methods : Advancing Methods and Applications. 5. PMID 24416081 DOI: 10.1039/C3Ay40810H  0.242
2007 Novick DM, Kreek MJ. Hepatitis C treatment, subcutaneous naltrexone implants, and methadone maintenance treatment. Hepatology (Baltimore, Md.). 46: 951-2. PMID 17705265 DOI: 10.1002/Hep.21718  0.241
2018 Collins D, Randesi M, da Rosa JC, Zhang Y, Kreek MJ. Oprm1 A112G, a single nucleotide polymorphism, alters expression of stress-responsive genes in multiple brain regions in male and female mice. Psychopharmacology. PMID 30027498 DOI: 10.1007/s00213-018-4965-x  0.241
1991 Novick DM, Ochshorn M, Kreek MJ. In vivo and in vitro studies of opiates and cellular immunity in narcotic addicts Advances in Experimental Medicine and Biology. 288: 159-170. PMID 1950730 DOI: 10.1007/978-1-4684-5925-8_18  0.24
1988 Novick DM, Farci P, Scott Croxson T, Taylor MB, Schneebaum CW, Eliana Lai M, Bach N, Senie RT, Gelb AM, Kreek MJ. Hepatitis d virus and human immunodeficiency virus antibodies in parenteral drug abusers who are hepatitis b surface antigen positive Journal of Infectious Diseases. 158: 795-803. PMID 3171227 DOI: 10.1093/Infdis/158.4.795  0.239
2011 Leri F, Zhou Y, Kreek M, Allen C, Levy A. S.10.01 Behavioural and neurochemical correlates of relapse vulnerability to cocaine and oxycodone seeking in laboratory rats European Neuropsychopharmacology. 21: S201. DOI: 10.1016/S0924-977X(11)70278-4  0.238
2003 Reed B, Zhang Y, Chait BT, Kreek MJ. Dynorphin A(1-17) biotransformation in striatum of freely moving rats using microdialysis and matrix-assisted laser desorption/ionization mass spectrometry. Journal of Neurochemistry. 86: 815-23. PMID 12887680 DOI: 10.1046/J.1471-4159.2003.01859.X  0.238
2004 LaForge KS, Nyberg F, Kreek MJ. Primary structure of guinea pig preprodynorphin and preproenkephalin mRNAs: multiple transcription initiation sites for preprodynorphin. Brain Research Bulletin. 63: 119-26. PMID 15130700 DOI: 10.1016/J.Brainresbull.2004.01.008  0.238
2005 Kellogg SH, Burns M, Coleman P, Stitzer M, Wale JB, Kreek MJ. Something of value: the introduction of contingency management interventions into the New York City Health and Hospital Addiction Treatment Service. Journal of Substance Abuse Treatment. 28: 57-65. PMID 15723733 DOI: 10.1016/J.Jsat.2004.10.007  0.236
1979 Kreek MJ, Hachey DL, Klein PD. Stereoselective disposition of methadone in man. Life Sciences. 24: 925-932. PMID 449601 DOI: 10.1016/0024-3205(79)90343-6  0.235
2010 Zhou Y, Proudnikov D, Yuferov V, Kreek MJ. Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases. Brain Research. 1314: 235-52. PMID 19914222 DOI: 10.1016/j.brainres.2009.11.015  0.234
1987 Kosten TR, Kreek MJ, Swift C, Carney MK, Ferdinands L. Beta endorphin levels in CSF during methadone maintenance. Life Sciences. 41: 1071-6. PMID 2956475 DOI: 10.1016/0024-3205(87)90623-0  0.234
2017 Zhou Y, Cowley RS, Ben K, Prisinzano TE, Kreek MJ. Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone. Brain Research. PMID 28263712 DOI: 10.1016/J.Brainres.2017.02.027  0.233
1996 Yuferov VP, Laforge KS, Spangler R, Maggos CE, Kreek MJ. Guinea pig preprodynorphin mRNA: primary structure and regional quantitation in the brain. Dna and Cell Biology. 15: 1105-12. PMID 8985124 DOI: 10.1089/Dna.1996.15.1105  0.233
2015 Zhang Y, Picetti R, Butelman ER, Ho A, Blendy JA, Kreek MJ. Mouse model of the OPRM1 (A118G) polymorphism: differential heroin self-administration behavior compared with wild-type mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1091-100. PMID 25336208 DOI: 10.1038/npp.2014.286  0.231
2012 Martinez AD, Dimova R, Marks KM, Beeder AB, Zeremski M, Kreek MJ, Talal AH. Integrated internist - addiction medicine - hepatology model for hepatitis C management for individuals on methadone maintenance. Journal of Viral Hepatitis. 19: 47-54. PMID 21129131 DOI: 10.1111/J.1365-2893.2010.01411.X  0.231
2008 Reed B, Bidlack JM, Chait BT, Kreek MJ. Extracellular biotransformation of beta-endorphin in rat striatum and cerebrospinal fluid. Journal of Neuroendocrinology. 20: 606-16. PMID 18363801 DOI: 10.1111/J.1365-2826.2008.01705.X  0.23
1993 Chou JZ, Albeck H, Kreek MJ. Determination of nalmefene in plasma by high-performance liquid chromatography with electrochemical detection and its application in pharmacokinetic studies. Journal of Chromatography B: Biomedical Sciences and Applications. 613: 359-364. PMID 8491826 DOI: 10.1016/0378-4347(93)80155-W  0.229
2015 Butelman ER, Kreek MJ. Corrigendum: Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders. Frontiers in Pharmacology. 6: 285. PMID 26648869 DOI: 10.3389/fphar.2015.00285  0.229
2013 Butelman ER, Kreek MJ. Kappa opioids: Problems and opportunities in analgesia Acs Symposium Series. 1131: 245-256. DOI: 10.1021/bk-2013-1131.ch013  0.228
1999 Borg L, Khuri E, Wells A, Melia D, Bergasa NV, Ho A, Kreek MJ. Methadone-maintained former heroin addicts, including those who are anti-HIV-1 seropositive, comply with and respond to hepatitis B vaccination. Addiction (Abingdon, England). 94: 489-93. PMID 10605845 DOI: 10.1046/J.1360-0443.1999.9444894.X  0.227
2008 Back SE, Waldrop AE, Saladin ME, Yeatts SD, Simpson A, McRae AL, Upadhyaya HP, Contini Sisson R, Spratt EG, Allen J, Kreek MJ, Brady KT. Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation. Psychoneuroendocrinology. 33: 560-8. PMID 18321653 DOI: 10.1016/J.Psyneuen.2008.01.012  0.227
2008 Novick DM, Kreek MJ. Critical issues in the treatment of hepatitis C virus infection in methadone maintenance patients. Addiction (Abingdon, England). 103: 905-18. PMID 18422827 DOI: 10.1111/J.1360-0443.2008.02188.X  0.226
2018 Zhou Y, Crowley R, Prisinzano T, Kreek MJ. Effects of Mesyl Salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice. Neuroscience Letters. PMID 29496608 DOI: 10.1016/J.Neulet.2018.02.056  0.225
2017 Butelman E, Bacciardi S, Maremmani AGI, Darst-Campbell M, Ray BM, Ducat E, Kreek MJ. Addictive diseases and depression comorbidity: Age trajectory and gender comparison Drug and Alcohol Dependence. 171. DOI: 10.1016/J.Drugalcdep.2016.08.095  0.223
2002 Piccolo P, Borg L, Lin A, Melia D, Ho A, Kreek MJ. Hepatitis C virus and human immunodeficiency virus-1 co-infection in former heroin addicts in methadone maintenance treatment. Journal of Addictive Diseases. 21: 55-66. PMID 12296502 DOI: 10.1300/J069V21N04_06  0.221
1985 Novick DM, Farci P, Karayiannis P, Gelb AM, Stenger RJ, Kreek MJ, Thomas HC. Hepatitis D virus antibody in HBsAg-positive and HBsAg-negative substance abusers with chronic liver disease Journal of Medical Virology. 15: 351-356. PMID 3884737 DOI: 10.1002/Jmv.1890150405  0.22
1995 Borg L, Kreek MJ. Clinical problems associated with interactions between methadone pharmacotherapy and medications used in the treatment of HIV-1-positive and AIDS patients Current Opinion in Psychiatry. 8: 199-202. DOI: 10.1097/00001504-199505000-00014  0.219
1992 Twist DJ, Culpepper-Morgan JA, Ragnarsson KT, Petrillo CR, Kreek MJ. Neuroendocrine changes during functional electrical stimulation American Journal of Physical Medicine and Rehabilitation. 71: 156-163. PMID 1627280 DOI: 10.1097/00002060-199206000-00006  0.219
2008 Bart G, Piccolo P, Zhang L, Jacobson I, Schaefer RA, Kreek MJ. Markers for hepatitis A, B and C in methadone maintained patients: an unexpectedly high co-infection with silent hepatitis B. Addiction (Abingdon, England). 103: 681-6. PMID 18339114 DOI: 10.1111/J.1360-0443.2008.02151.X  0.218
1989 Jarlais DD, Friedman S, Novick D, Sotheran J, Thomas P, Yancovitz S, Mildvan D, Weber J, Kreek M, Maslansky R, Bartelme S, Spira T, Marmor M. HIV-1 infection among intravenous drug users in Manhattan, New York City, from 1977 through 1987 International Journal of Gynecology & Obstetrics. 29: 383-383. DOI: 10.1016/0020-7292(89)90367-6  0.218
1984 Kreek MJ, Stimmel B. Alcoholism and polydrug use: the need for the "basics". Advances in Alcohol and Substance Abuse. 3: 1-6. PMID 6507183 DOI: 10.1300/J251V03N04_01  0.216
1967 Kreek MJ, Weser E, Sleisenger MH, Jeffries GH. Idiopathic cholestasis of pregnancy. The response to challenge with the synthetic estrogen, ethinyl estradiol. The New England Journal of Medicine. 277: 1391-1395. PMID 6081143 DOI: 10.1056/Nejm196712282772603  0.216
2012 Crystal H, Kleyman I, Anastos K, Lazar J, Cohen M, Liu C, Pearce L, Golub E, Valcour V, Ho A, Strickler H, Peters M, Kovacs A, Holman S, Kreek MJ, et al. Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV Study. Journal of Acquired Immune Deficiency Syndromes (1999). 59: 149-54. PMID 22107817 DOI: 10.1097/Qai.0B013E318240566B  0.215
2020 Randesi M, Levran O, den Brink WV, Blanken P, van Ree JM, Ott J, Kreek MJ. Further evidence for association of ,  and  variants with opioid dependence. Pharmacogenomics. PMID 32757697 DOI: 10.2217/Pgs-2020-0045  0.215
2011 Crystal HA, Weedon J, Holman S, Manly J, Valcour V, Cohen M, Anastos K, Liu C, Mack WJ, Golub E, Lazar J, Ho A, Kreek MJ, Kaplan RC. Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women. Journal of Neurovirology. 17: 469-76. PMID 22006469 DOI: 10.1007/S13365-011-0052-3  0.215
2022 Reed B, Miller M, Michino M, Butelman ER, Ben-Ezra A, Pikus P, Morochnik M, Kim Y, Ripka A, Vacca J, Kreek MJ. Characterization of Pyrrolidinyl-hexahydro-pyranopiperazines as a Novel Kappa Opioid Receptor Agonist Scaffold. Acs Chemical Neuroscience. PMID 35738565 DOI: 10.1021/acschemneuro.2c00258  0.214
2004 Proudnikov D, LaForge KS, Kreek MJ. High-throughput molecular haplotype analysis (allelic assignment) of single-nucleotide polymorphisms by fluorescent polymerase chain reaction. Analytical Biochemistry. 335: 165-7. PMID 15519584 DOI: 10.1016/J.Ab.2004.08.025  0.214
2011 Kreek MJ. Extreme marginalization: addiction and other mental health disorders, stigma, and imprisonment. Annals of the New York Academy of Sciences. 1231: 65-72. PMID 21884162 DOI: 10.1111/J.1749-6632.2011.06152.X  0.214
1996 Chou JZ, Chait BT, Wang R, Kreek MJ. Differential biotransformation of dynorphin A (1-17) and dynorphin A (1-13) peptides in human blood, ex vivo. Peptides. 17: 983-90. PMID 8899817 DOI: 10.1016/0196-9781(96)00154-4  0.209
1997 Ghodse AH, Kreek M. A rave at ecstasy Current Opinion in Psychiatry. 10: 191-193. DOI: 10.1097/00001504-199705000-00002  0.209
1992 Novick DM, Kreek MJ. Methadone and immune function The American Journal of Medicine. 92: 113-114. PMID 1731504 DOI: 10.1016/0002-9343(92)90031-6  0.209
1967 Kreek MJ, Sleisenger MH, Jeffries GH. Recurrent cholestatic jaundice of pregnancy with demonstrated estrogen sensitivity The American Journal of Medicine. 43: 795-803. PMID 6054843 DOI: 10.1016/0002-9343(67)90122-2  0.208
2008 Schlussman SD, Zhang Y, Hsu NM, Allen JM, Ho A, Kreek MJ. Heroin-induced locomotor activity and conditioned place preference in C57BL/6J and 129P3/J mice. Neuroscience Letters. 440: 284-8. PMID 18579303 DOI: 10.1016/j.neulet.2008.05.103  0.208
1975 Kreek MJ, Khuri E, Joseph H. A New Heroin Epidemic Annals of Internal Medicine. 83: 420-421. PMID 1180443 DOI: 10.7326/0003-4819-83-3-420  0.205
2004 Berrettini W, Bierut L, Crowley TJ, Cubells JF, Frascella J, Gelernter J, Hewitt JK, Kreek MJ, Lachman H, Leppert M, Li MD, Madden P, Miner C, Pollock JD, Pomerleau O, et al. Setting priorities for genomic research. Science (New York, N.Y.). 304: 1445-7; author reply. PMID 15178784 DOI: 10.1126/Science.304.5676.1445C  0.204
2022 Gaddis N, Mathur R, Marks J, Zhou L, Quach B, Waldrop A, Levran O, Agrawal A, Randesi M, Adelson M, Jeffries PW, Martin NG, Degenhardt L, Montgomery GW, Wetherill L, ... ... Kreek MJ, et al. Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. Scientific Reports. 12: 16873. PMID 36207451 DOI: 10.1038/s41598-022-21003-y  0.204
1978 Kreek MJ. Medical Complications In Methadone Patients Annals of the New York Academy of Sciences. 311: 110-134. PMID 369431 DOI: 10.1111/J.1749-6632.1978.Tb16769.X  0.202
1995 Yuferov V, Culpepper-Morgan JA, Claye LH, LaForge KS, Kreek MJ. Quantification of preprodynorphin (DYN) mRNA in guinea pig gut using a highly sensitive solution hybridization assay Gastroenterology. 108. DOI: 10.1016/0016-5085(95)28381-1  0.202
2011 Schlussman SD, Cassin J, Zhang Y, Levran O, Ho A, Kreek MJ. Regional mRNA expression of the endogenous opioid and dopaminergic systems in brains of C57BL/6J and 129P3/J mice: strain and heroin effects. Pharmacology, Biochemistry, and Behavior. 100: 8-16. PMID 21807019 DOI: 10.1016/j.pbb.2011.07.013  0.201
2018 Yuferov V, Zhang Y, Liang Y, Zhao C, Randesi M, Kreek MJ. Oxycodone Self-Administration Induces Alterations in Expression of Integrin, Semaphorin and Ephrin Genes in the Mouse Striatum. Frontiers in Psychiatry. 9: 257. PMID 29946272 DOI: 10.3389/fpsyt.2018.00257  0.201
2017 Zhou Y, Rubinstein M, Low M, Kreek MJ. V1b receptor antagonist SSR149415 and naltrexone synergistically decrease excessive alcohol drinking in male and female mice. Alcoholism, Clinical and Experimental Research. PMID 29105118 DOI: 10.1111/Acer.13544  0.2
2013 Chou JZ, Kreek MJ, Chait BT. Matrix-assisted laser desorption mass spectrometry of biotransformation products of dynorphin a in vitro. Journal of the American Society For Mass Spectrometry. 5: 10-6. PMID 24226135 DOI: 10.1016/1044-0305(94)85078-X  0.199
1975 Small DM, Bennett P, Carey M, Grundy S, Lester R, Palmer R, Ahrens A, Balint J, Neiderhiser D, Ostrow J, Baum G, Colten H, Cussler E, Den Besten L, Gorbach S, ... ... Kreek M, et al. Diseases of the gallbladder and biliary passages Gastroenterology. 69: 1121-1130. DOI: 10.1016/S0016-5085(19)32388-1  0.199
2002 Piccolo P, Bart G, Borg L, Handy S, Ho A, Zhang L, Kreek MJ. Gender differences in HCV viral load among methadone-maintained patients Journal of Hepatology. 36: 124. DOI: 10.1016/S0168-8278(02)80441-X  0.198
1980 Kreek MJ, Balint JA. “Skinny needle” cholangiography—Results of a pilot study of a voluntary prospective method for gathering risk data on new procedures Gastroenterology. 78: 598-604. DOI: 10.1016/0016-5085(80)90878-1  0.198
2015 Deutsch-Feldman M, Picetti R, Seip-Cammack K, Zhou Y, Kreek MJ. Effects of handling and vehicle injections on adrenocorticotropic and corticosterone concentrations in Sprague-Dawley compared with Lewis rats. Journal of the American Association For Laboratory Animal Science : Jaalas. 54: 35-9. PMID 25651089  0.196
2021 Zhou Y, Freeman K, Setola V, Cao D, Kaski S, Kreek MJ, Liu-Chen LY. Preclinical Studies on Nalfurafine (TRK-820), a Clinically Used KOR Agonist. Handbook of Experimental Pharmacology. PMID 33834276 DOI: 10.1007/164_2021_443  0.195
2010 Comer SD, Bickel WK, Yi R, de Wit H, Higgins ST, Wenger GR, Johanson CE, Kreek MJ. Human behavioral pharmacology, past, present, and future: symposium presented at the 50th annual meeting of the Behavioral Pharmacology Society. Behavioural Pharmacology. 21: 251-77. PMID 20664330 DOI: 10.1097/Fbp.0B013E32833Bb9F8  0.19
1996 Claye LH, Unterwald EM, Ho A, Kreek MJ. Both dynorphin A(1-17) and [Des-Tyr1]dynorphin A(2-17) inhibit adenylyl cyclase activity in rat caudate putamen. The Journal of Pharmacology and Experimental Therapeutics. 277: 359-65. PMID 8613942  0.183
2007 Kreek MJ. Opioids, dopamine, stress, and the addictions. Dialogues in Clinical Neuroscience. 9: 363-78. PMID 18286797  0.181
1967 Kreek MJ, Raziano JV, Hardy RE, Jeffries GH. Portal Hypertension with Bleeding Vaginal Varices Annals of Internal Medicine. 66: 756-759. PMID 6067181 DOI: 10.7326/0003-4819-66-4-756  0.175
2007 Adelson M, Peles E, Bodner G, Kreek MJ. Correlation between high methadone doses and methadone serum levels in methadone maintenance treatment (MMT) patients. Journal of Addictive Diseases. 26: 15-26. PMID 17439864 DOI: 10.1300/J069v26n01_03  0.169
2020 Kreek MJ. Bruce S. McEwen, Ph.D. Neuropsychopharmacology. 45: 1079-1079. DOI: 10.1038/S41386-020-0645-8  0.168
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