| Year |
Citation |
Score |
| 2023 |
Bose S, de Heus C, Kennedy ME, Wang F, Jentsch TJ, Klumperman J, Stauber T. Impaired Autophagic Clearance with a Gain-of-Function Variant of the Lysosomal Cl/H Exchanger ClC-7. Biomolecules. 13. PMID 38136669 DOI: 10.3390/biom13121799 |
0.308 |
|
| 2023 |
Liu H, Polovitskaya MM, Yang L, Li M, Li H, Han Z, Wu J, Zhang Q, Jentsch TJ, Liao J. Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels. Cell Reports. 42: 112926. PMID 37543949 DOI: 10.1016/j.celrep.2023.112926 |
0.315 |
|
| 2022 |
López-Cayuqueo KI, Planells-Cases R, Pietzke M, Oliveras A, Kempa S, Bachmann S, Jentsch TJ. Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy. Journal of the American Society of Nephrology : Jasn. PMID 35777784 DOI: 10.1681/ASN.2021111458 |
0.364 |
|
| 2022 |
Zeziulia M, Blin S, Schmitt FW, Lehmann M, Jentsch TJ. Proton-gated anion transport governs macropinosome shrinkage. Nature Cell Biology. 24: 885-895. PMID 35590106 DOI: 10.1038/s41556-022-00912-0 |
0.371 |
|
| 2022 |
Wang C, Polovitskaya MM, Delgado BD, Jentsch TJ, Long SB. Gating choreography and mechanism of the human proton-activated chloride channel ASOR. Science Advances. 8: eabm3942. PMID 35108041 DOI: 10.1126/sciadv.abm3942 |
0.325 |
|
| 2021 |
Duncan AR, Polovitskaya MM, Gaitán-Peñas H, Bertelli S, VanNoy GE, Grant PE, O'Donnell-Luria A, Valivullah Z, Lovgren AK, England EM, Agolini E, Madden JA, Schmitz-Abe K, Kritzer A, Hawley P, ... ... Jentsch TJ, et al. Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders. American Journal of Human Genetics. PMID 34186028 DOI: 10.1016/j.ajhg.2021.06.003 |
0.308 |
|
| 2020 |
Göppner C, Soria AH, Hoegg-Beiler MB, Jentsch TJ. Cellular basis of ClC-2 Cl channel-related brain and testis pathologies. The Journal of Biological Chemistry. 296: 100074. PMID 33410413 DOI: 10.1074/jbc.RA120.016031 |
0.302 |
|
| 2020 |
Göppner C, Soria AH, Hoegg-Beiler MB, Jentsch TJ. Cellular basis of ClC-2 Cl- channel-related brain and testis pathologies. The Journal of Biological Chemistry. PMID 33187987 DOI: 10.1074/jbc.RA120.016031 |
0.391 |
|
| 2020 |
Zhou C, Chen X, Planells-Cases R, Chu J, Wang L, Cao L, Li Z, López-Cayuqueo KI, Xie Y, Ye S, Wang X, Ullrich F, Ma S, Fang Y, Zhang X, ... ... Jentsch TJ, et al. Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity. Immunity. PMID 32277911 DOI: 10.1016/J.Immuni.2020.03.016 |
0.631 |
|
| 2020 |
Weinert S, Gimber N, Deuschel D, Stuhlmann T, Puchkov D, Farsi Z, Ludwig CF, Novarino G, López-Cayuqueo KI, Planells-Cases R, Jentsch TJ. Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration. The Embo Journal. e103358. PMID 32118314 DOI: 10.15252/Embj.2019103358 |
0.359 |
|
| 2019 |
Göppner C, Orozco IJ, Hoegg-Beiler MB, Soria AH, Hübner CA, Fernandes-Rosa FL, Boulkroun S, Zennaro MC, Jentsch TJ. Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism. Nature Communications. 10: 4678. PMID 31615979 DOI: 10.1038/S41467-019-12113-9 |
0.435 |
|
| 2019 |
Ullrich F, Blin S, Lazarow K, Daubitz T, von Kries JP, Jentsch TJ. Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels. Elife. 8. PMID 31318332 DOI: 10.7554/Elife.49187 |
0.686 |
|
| 2019 |
Ullrich F, Blin S, Lazarow K, Daubitz T, Kries JPv, Jentsch TJ. Author response: Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels Elife. DOI: 10.7554/Elife.49187.028 |
0.639 |
|
| 2018 |
Zhou P, Polovitskaya MM, Jentsch TJ. LRRC8 amino-termini influence pore properties and gating of volume-regulated VRAC anion channels. The Journal of Biological Chemistry. PMID 29925591 DOI: 10.1074/Jbc.Ra118.002853 |
0.511 |
|
| 2018 |
Lück JC, Puchkov D, Ullrich F, Jentsch TJ. LRRC8/VRAC anion channels are required for late stages of spermatid development in mice. The Journal of Biological Chemistry. PMID 29880644 DOI: 10.1074/Jbc.Ra118.003853 |
0.661 |
|
| 2018 |
Jentsch TJ, Pusch M. CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease. Physiological Reviews. 98: 1493-1590. PMID 29845874 DOI: 10.1152/Physrev.00047.2017 |
0.488 |
|
| 2018 |
Stuhlmann T, Planells-Cases R, Jentsch TJ. LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion. Nature Communications. 9: 1974. PMID 29773801 DOI: 10.1038/S41467-018-04353-Y |
0.305 |
|
| 2018 |
Münch J, Billig G, Huebner CA, Leinders-Zufall T, Zufall F, Jentsch TJ. Ca-activated Cl currents in the murine vomeronasal organ enhance neuronal spiking but are dispensable for male-male aggression. The Journal of Biological Chemistry. PMID 29769308 DOI: 10.1074/Jbc.Ra118.003153 |
0.402 |
|
| 2018 |
Fernandes-Rosa FL, Daniil G, Orozco IJ, Göppner C, El Zein R, Jain V, Boulkroun S, Jeunemaitre X, Amar L, Lefebvre H, Schwarzmayr T, Strom TM, Jentsch TJ, Zennaro MC. A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism. Nature Genetics. PMID 29403012 DOI: 10.1038/S41588-018-0053-8 |
0.5 |
|
| 2017 |
Julio-Kalajzić F, Villanueva S, Burgos J, Ojeda M, Cid LP, Jentsch TJ, Sepúlveda FV. K2P TASK-2 and KCNQ1/KCNE3 K(+) channels are major players contributing to intestinal anion and fluid secretion. The Journal of Physiology. PMID 29143340 DOI: 10.1113/Jp275178 |
0.486 |
|
| 2017 |
Oberheide K, Puchkov D, Jentsch TJ. Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation. The Journal of Biological Chemistry. PMID 28476888 DOI: 10.1074/Jbc.M117.784108 |
0.341 |
|
| 2017 |
Lutter D, Ullrich F, Lueck JC, Kempa S, Jentsch TJ. Selective transport of neurotransmitters and -modulators by distinct volume-regulated LRRC8 anion channels. Journal of Cell Science. PMID 28193731 DOI: 10.1242/Jcs.196253 |
0.656 |
|
| 2016 |
Hennings JC, Andrini O, Picard N, Paulais M, Huebner AK, Cayuqueo IK, Bignon Y, Keck M, Cornière N, Böhm D, Jentsch TJ, Chambrey R, Teulon J, Hübner CA, Eladari D. The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron. Journal of the American Society of Nephrology : Jasn. PMID 27335120 DOI: 10.1681/Asn.2016010085 |
0.448 |
|
| 2016 |
Ullrich F, Reincke SM, Voss FK, Stauber T, Jentsch TJ. Inactivation and Anion Selectivity of Volume-Regulated VRAC Channels Depend on Carboxy-Terminal Residues of the First Extracellular Loop. The Journal of Biological Chemistry. PMID 27325695 DOI: 10.1074/Jbc.M116.739342 |
0.679 |
|
| 2016 |
Jentsch TJ. VRACs and other ion channels and transporters in the regulation of cell volume and beyond. Nature Reviews. Molecular Cell Biology. PMID 27033257 DOI: 10.1038/Nrm.2016.29 |
0.446 |
|
| 2016 |
Schütze S, Orozco IJ, Jentsch TJ. KCNQ Potassium Channels Modulate Sensitivity of Skin D-hair Mechanoreceptors. The Journal of Biological Chemistry. PMID 26733196 DOI: 10.1074/Jbc.M115.681098 |
0.398 |
|
| 2015 |
Jentsch TJ, Lutter D, Planells-Cases R, Ullrich F, Voss FK. VRAC: molecular identification as LRRC8 heteromers with differential functions. Pflugers Archiv : European Journal of Physiology. PMID 26635246 DOI: 10.1007/S00424-015-1766-5 |
0.644 |
|
| 2015 |
Planells-Cases R, Lutter D, Guyader C, Gerhards NM, Ullrich F, Elger DA, Kucukosmanoglu A, Xu G, Voss FK, Reincke SM, Stauber T, Blomen VA, Vis DJ, Wessels LF, Brummelkamp TR, ... ... Jentsch TJ, et al. Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs. The Embo Journal. PMID 26530471 DOI: 10.15252/Embj.201592409 |
0.616 |
|
| 2015 |
Varga RE, Khundadze M, Damme M, Nietzsche S, Hoffmann B, Stauber T, Koch N, Hennings JC, Franzka P, Huebner AK, Kessels MM, Biskup C, Jentsch TJ, Qualmann B, Braulke T, et al. In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11. Plos Genetics. 11: e1005454. PMID 26284655 DOI: 10.1371/Journal.Pgen.1005454 |
0.349 |
|
| 2015 |
Jentsch TJ, Hoegg-Beiler MB, Vogt J. Departure gate of acidic Ca2+ confirmed. The Embo Journal. 34: 1737-9. PMID 26022292 DOI: 10.15252/Embj.201591884 |
0.327 |
|
| 2015 |
Jentsch TJ. Discovery of CLC transport proteins: cloning, structure, function and pathophysiology. The Journal of Physiology. PMID 25703180 DOI: 10.1113/jphysiol.2014.270043 |
0.384 |
|
| 2015 |
Fidzinski P, Korotkova T, Heidenreich M, Maier N, Schuetze S, Kobler O, Zuschratter W, Schmitz D, Ponomarenko A, Jentsch TJ. KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations. Nature Communications. 6: 6254. PMID 25649132 DOI: 10.1038/Ncomms7254 |
0.408 |
|
| 2015 |
Jentsch TJ. Discovery of CLC transport proteins: Cloning, structure, function and pathophysiology. The Journal of Physiology. PMID 25590607 DOI: 10.1113/Jp270043 |
0.485 |
|
| 2014 |
Schleifenbaum J, Kassmann M, Szijártó IA, Hercule HC, Tano JY, Weinert S, Heidenreich M, Pathan AR, Anistan YM, Alenina N, Rusch NJ, Bader M, Jentsch TJ, Gollasch M. Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries. Circulation Research. 115: 263-72. PMID 24838176 DOI: 10.1161/Circresaha.115.302882 |
0.456 |
|
| 2014 |
Weinert S, Jabs S, Hohensee S, Chan WL, Kornak U, Jentsch TJ. Transport activity and presence of ClC-7/Ostm1 complex account for different cellular functions. Embo Reports. 15: 784-91. PMID 24820037 DOI: 10.15252/Embr.201438553 |
0.37 |
|
| 2014 |
Voss FK, Ullrich F, Münch J, Lazarow K, Lutter D, Mah N, Andrade-Navarro MA, von Kries JP, Stauber T, Jentsch TJ. Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC. Science (New York, N.Y.). 344: 634-8. PMID 24790029 DOI: 10.1126/Science.1252826 |
0.679 |
|
| 2014 |
Hoegg-Beiler MB, Sirisi S, Orozco IJ, Ferrer I, Hohensee S, Auberson M, Gödde K, Vilches C, de Heredia ML, Nunes V, Estévez R, Jentsch TJ. Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction. Nature Communications. 5: 3475. PMID 24647135 DOI: 10.1038/Ncomms4475 |
0.456 |
|
| 2014 |
Sartelet A, Stauber T, Coppieters W, Ludwig CF, Fasquelle C, Druet T, Zhang Z, Ahariz N, Cambisano N, Jentsch TJ, Charlier C. A missense mutation accelerating the gating of the lysosomal Cl-/H+-exchanger ClC-7/Ostm1 causes osteopetrosis with gingival hamartomas in cattle. Disease Models & Mechanisms. 7: 119-28. PMID 24159188 DOI: 10.1242/Dmm.012500 |
0.411 |
|
| 2014 |
Barvencik F, Kurth I, Koehne T, Stauber T, Zustin J, Tsiakas K, Ludwig CF, Beil FT, Pestka JM, Hahn M, Santer R, Supanchart C, Kornak U, Del Fattore A, Jentsch TJ, et al. CLCN7 and TCIRG1 mutations differentially affect bone matrix mineralization in osteopetrotic individuals. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 982-91. PMID 24108692 DOI: 10.1002/Jbmr.2100 |
0.312 |
|
| 2014 |
Supanchart C, Wartosch L, Schlack C, Kühnisch J, Felsenberg D, Fuhrmann JC, de Vernejoul MC, Jentsch TJ, Kornak U. ClC-7 expression levels critically regulate bone turnover, but not gastric acid secretion. Bone. 58: 92-102. PMID 24103576 DOI: 10.1016/J.Bone.2013.09.022 |
0.315 |
|
| 2013 |
Ludwig CF, Ullrich F, Leisle L, Stauber T, Jentsch TJ. Common gating of both CLC transporter subunits underlies voltage-dependent activation of the 2Cl-/1H+ exchanger ClC-7/Ostm1. The Journal of Biological Chemistry. 288: 28611-9. PMID 23983121 DOI: 10.1074/Jbc.M113.509364 |
0.684 |
|
| 2013 |
Veeramah KR, Johnstone L, Karafet TM, Wolf D, Sprissler R, Salogiannis J, Barth-Maron A, Greenberg ME, Stuhlmann T, Weinert S, Jentsch TJ, Pazzi M, Restifo LL, Talwar D, Erickson RP, et al. Exome sequencing reveals new causal mutations in children with epileptic encephalopathies. Epilepsia. 54: 1270-81. PMID 23647072 DOI: 10.1111/Epi.12201 |
0.311 |
|
| 2013 |
Spitzmaul G, Tolosa L, Winkelman BH, Heidenreich M, Frens MA, Chabbert C, de Zeeuw CI, Jentsch TJ. Vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models. The Journal of Biological Chemistry. 288: 9334-44. PMID 23408425 DOI: 10.1074/Jbc.M112.433383 |
0.501 |
|
| 2013 |
Stauber T, Jentsch TJ. Chloride in vesicular trafficking and function. Annual Review of Physiology. 75: 453-77. PMID 23092411 DOI: 10.1146/Annurev-Physiol-030212-183702 |
0.366 |
|
| 2012 |
Stauber T, Weinert S, Jentsch TJ. Cell biology and physiology of CLC chloride channels and transporters. Comprehensive Physiology. 2: 1701-44. PMID 23723021 DOI: 10.1002/Cphy.C110038 |
0.509 |
|
| 2012 |
Hennings JC, Picard N, Huebner AK, Stauber T, Maier H, Brown D, Jentsch TJ, Vargas-Poussou R, Eladari D, Hübner CA. A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule. Embo Molecular Medicine. 4: 1057-71. PMID 22933323 DOI: 10.1002/Emmm.201201527 |
0.314 |
|
| 2012 |
Jeworutzki E, López-Hernández T, Capdevila-Nortes X, Sirisi S, Bengtsson L, Montolio M, Zifarelli G, Arnedo T, Müller CS, Schulte U, Nunes V, MartÃnez A, Jentsch TJ, Gasull X, Pusch M, et al. GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit. Neuron. 73: 951-61. PMID 22405205 DOI: 10.1016/J.Neuron.2011.12.039 |
0.509 |
|
| 2012 |
Seja P, Schonewille M, Spitzmaul G, Badura A, Klein I, Rudhard Y, Wisden W, Hübner CA, De Zeeuw CI, Jentsch TJ. Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning. The Embo Journal. 31: 1217-30. PMID 22252133 DOI: 10.1038/Emboj.2011.488 |
0.34 |
|
| 2012 |
Heidenreich M, Lechner SG, Vardanyan V, Wetzel C, Cremers CW, De Leenheer EM, Aránguez G, Moreno-Pelayo MÃ, Jentsch TJ, Lewin GR. KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man. Nature Neuroscience. 15: 138-45. PMID 22101641 DOI: 10.1038/Nn.2985 |
0.411 |
|
| 2011 |
Khalilov I, Chazal G, Chudotvorova I, Pellegrino C, Corby S, Ferrand N, Gubkina O, Nardou R, Tyzio R, Yamamoto S, Jentsch TJ, Hübner CA, Gaiarsa JL, Ben-Ari Y, Medina I. Enhanced Synaptic Activity and Epileptiform Events in the Embryonic KCC2 Deficient Hippocampus. Frontiers in Cellular Neuroscience. 5: 23. PMID 22065950 DOI: 10.3389/Fncel.2011.00023 |
0.331 |
|
| 2011 |
Nomura N, Tajima M, Sugawara N, Morimoto T, Kondo Y, Ohno M, Uchida K, Mutig K, Bachmann S, Soleimani M, Ohta E, Ohta A, Sohara E, Okado T, Rai T, ... Jentsch TJ, et al. Generation and analyses of R8L barttin knockin mouse. American Journal of Physiology. Renal Physiology. 301: F297-307. PMID 21593186 DOI: 10.1152/Ajprenal.00604.2010 |
0.464 |
|
| 2011 |
Leisle L, Ludwig CF, Wagner FA, Jentsch TJ, Stauber T. ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity. The Embo Journal. 30: 2140-52. PMID 21527911 DOI: 10.1038/Emboj.2011.137 |
0.465 |
|
| 2011 |
Billig GM, Pál B, Fidzinski P, Jentsch TJ. Ca2+-activated Cl− currents are dispensable for olfaction. Nature Neuroscience. 14: 763-9. PMID 21516098 DOI: 10.1038/Nn.2821 |
0.455 |
|
| 2010 |
Pressey SN, O'Donnell KJ, Stauber T, Fuhrmann JC, Tyynelä J, Jentsch TJ, Cooper JD. Distinct neuropathologic phenotypes after disrupting the chloride transport proteins ClC-6 or ClC-7/Ostm1. Journal of Neuropathology and Experimental Neurology. 69: 1228-46. PMID 21107136 DOI: 10.1097/Nen.0B013E3181Ffe742 |
0.348 |
|
| 2010 |
Stauber T, Jentsch TJ. Sorting motifs of the endosomal/lysosomal CLC chloride transporters. The Journal of Biological Chemistry. 285: 34537-48. PMID 20817731 DOI: 10.1074/Jbc.M110.162545 |
0.37 |
|
| 2010 |
Steinberg BE, Huynh KK, Brodovitch A, Jabs S, Stauber T, Jentsch TJ, Grinstein S. A cation counterflux supports lysosomal acidification. The Journal of Cell Biology. 189: 1171-86. PMID 20566682 DOI: 10.1085/Jgp1362Oia2 |
0.376 |
|
| 2010 |
Tzingounis AV, Heidenreich M, Kharkovets T, Spitzmaul G, Jensen HS, Nicoll RA, Jentsch TJ. The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 107: 10232-7. PMID 20534576 DOI: 10.1073/Pnas.1004644107 |
0.653 |
|
| 2010 |
Neagoe I, Stauber T, Fidzinski P, Bergsdorf EY, Jentsch TJ. The late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression. The Journal of Biological Chemistry. 285: 21689-97. PMID 20466723 DOI: 10.1074/Jbc.M110.125971 |
0.491 |
|
| 2010 |
Novarino G, Weinert S, Rickheit G, Jentsch TJ. Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis. Science (New York, N.Y.). 328: 1398-401. PMID 20430975 DOI: 10.1126/Science.1188070 |
0.418 |
|
| 2010 |
Weinert S, Jabs S, Supanchart C, Schweizer M, Gimber N, Richter M, Rademann J, Stauber T, Kornak U, Jentsch TJ. Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulation. Science (New York, N.Y.). 328: 1401-3. PMID 20430974 DOI: 10.1126/Science.1188072 |
0.401 |
|
| 2010 |
Rickheit G, Wartosch L, Schaffer S, Stobrawa SM, Novarino G, Weinert S, Jentsch TJ. Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation. The Journal of Biological Chemistry. 285: 17595-603. PMID 20351103 DOI: 10.1074/Jbc.M110.115600 |
0.373 |
|
| 2010 |
Scheper GC, van Berkel CG, Leisle L, de Groot KE, Errami A, Jentsch TJ, Van der Knaap MS. Analysis of CLCN2 as candidate gene for megalencephalic leukoencephalopathy with subcortical cysts. Genetic Testing and Molecular Biomarkers. 14: 255-7. PMID 20187760 DOI: 10.1089/Gtmb.2009.0148 |
0.371 |
|
| 2010 |
Preston P, Wartosch L, Günzel D, Fromm M, Kongsuphol P, Ousingsawat J, Kunzelmann K, Barhanin J, Warth R, Jentsch TJ. Disruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transport. The Journal of Biological Chemistry. 285: 7165-75. PMID 20051516 DOI: 10.1074/Jbc.M109.047829 |
0.497 |
|
| 2010 |
Stauber T, Novarino G, Jentsch TJ. The CLC family of chloride channels and transporters Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. 209-231. DOI: 10.1016/B978-0-12-374373-2.00012-1 |
0.326 |
|
| 2009 |
Zdebik AA, Wangemann P, Jentsch TJ. Potassium ion movement in the inner ear: insights from genetic disease and mouse models. Physiology (Bethesda, Md.). 24: 307-16. PMID 19815857 DOI: 10.1152/Physiol.00018.2009 |
0.392 |
|
| 2009 |
Planells-Cases R, Jentsch TJ. Chloride channelopathies. Biochimica Et Biophysica Acta. 1792: 173-89. PMID 19708126 DOI: 10.1016/j.bbadis.2009.02.002 |
0.362 |
|
| 2009 |
Wartosch L, Fuhrmann JC, Schweizer M, Stauber T, Jentsch TJ. Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4056-68. PMID 19661288 DOI: 10.1096/Fj.09-130880 |
0.428 |
|
| 2009 |
Jentsch TJ. To the editor. CLC chloride channels and transporters: from genes to protein structure, pathology and physiology. Critical Reviews in Biochemistry and Molecular Biology. 44: 64. PMID 19514889 DOI: 10.1080/10409230902814887 |
0.439 |
|
| 2009 |
Pfeffer CK, Stein V, Keating DJ, Maier H, Rinke I, Rudhard Y, Hentschke M, Rune GM, Jentsch TJ, Hübner CA. NKCC1-dependent GABAergic excitation drives synaptic network maturation during early hippocampal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3419-30. PMID 19295148 DOI: 10.1523/Jneurosci.1377-08.2009 |
0.768 |
|
| 2009 |
Bergsdorf EY, Zdebik AA, Jentsch TJ. Residues important for nitrate/proton coupling in plant and mammalian CLC transporters. The Journal of Biological Chemistry. 284: 11184-93. PMID 19261613 DOI: 10.1074/Jbc.M901170200 |
0.392 |
|
| 2009 |
Plans V, Rickheit G, Jentsch TJ. Physiological roles of CLC Cl(-)/H (+) exchangers in renal proximal tubules. Pflã¼Gers Archiv : European Journal of Physiology. 458: 23-37. PMID 18853181 DOI: 10.1007/S00424-008-0597-Z |
0.391 |
|
| 2008 |
Hübner CA, Jentsch TJ. Channelopathies of transepithelial transport and vesicular function. Advances in Genetics. 63: 113-52. PMID 19185187 DOI: 10.1016/S0065-2660(08)01005-5 |
0.406 |
|
| 2008 |
Maritzen T, Keating DJ, Neagoe I, Zdebik AA, Jentsch TJ. Role of the vesicular chloride transporter ClC-3 in neuroendocrine tissue. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10587-98. PMID 18923035 DOI: 10.1523/Jneurosci.3750-08.2008 |
0.338 |
|
| 2008 |
Rickheit G, Maier H, Strenzke N, Andreescu CE, De Zeeuw CI, Muenscher A, Zdebik AA, Jentsch TJ. Endocochlear potential depends on Cl- channels: mechanism underlying deafness in Bartter syndrome IV. The Embo Journal. 27: 2907-17. PMID 18833191 DOI: 10.1038/Emboj.2008.203 |
0.492 |
|
| 2008 |
Jentsch TJ. CLC chloride channels and transporters: from genes to protein structure, pathology and physiology. Critical Reviews in Biochemistry and Molecular Biology. 43: 3-36. PMID 18307107 DOI: 10.1080/10409230701829110 |
0.461 |
|
| 2008 |
Hansen HH, Waroux O, Seutin V, Jentsch TJ, Aznar S, Mikkelsen JD. Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS. The Journal of Physiology. 586: 1823-32. PMID 18174210 DOI: 10.1113/Jphysiol.2007.149450 |
0.493 |
|
| 2008 |
Zdebik AA, Zifarelli G, Bergsdorf EY, Soliani P, Scheel O, Jentsch TJ, Pusch M. Determinants of anion-proton coupling in mammalian endosomal CLC proteins. The Journal of Biological Chemistry. 283: 4219-27. PMID 18063579 DOI: 10.1074/Jbc.M708368200 |
0.415 |
|
| 2007 |
Blanz J, Schweizer M, Auberson M, Maier H, Muenscher A, Hübner CA, Jentsch TJ. Leukoencephalopathy upon disruption of the chloride channel ClC-2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6581-9. PMID 17567819 DOI: 10.1523/Jneurosci.0338-07.2007 |
0.422 |
|
| 2007 |
Rust MB, Alper SL, Rudhard Y, Shmukler BE, Vicente R, Brugnara C, Trudel M, Jentsch TJ, Hübner CA. Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice. The Journal of Clinical Investigation. 117: 1708-17. PMID 17510708 DOI: 10.1172/Jci30630 |
0.332 |
|
| 2007 |
Jentsch TJ. Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters. The Journal of Physiology. 578: 633-40. PMID 17110406 DOI: 10.1113/Jphysiol.2006.124719 |
0.511 |
|
| 2007 |
Wartosch L, Fuhrmann JC, Jentsch TJ. Dissection of a complex phenotype: Conditional inactivation of the chloride channel ClC-7 Gbm Annual Spring Meeting Mosbach 2007. 2007. DOI: 10.1240/SAV_GBM_2007_M_001703 |
0.332 |
|
| 2006 |
Poët M, Kornak U, Schweizer M, Zdebik AA, Scheel O, Hoelter S, Wurst W, Schmitt A, Fuhrmann JC, Planells-Cases R, Mole SE, Hübner CA, Jentsch TJ. Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6. Proceedings of the National Academy of Sciences of the United States of America. 103: 13854-9. PMID 16950870 DOI: 10.1073/Pnas.0606137103 |
0.361 |
|
| 2006 |
Schwake M, Athanasiadu D, Beimgraben C, Blanz J, Beck C, Jentsch TJ, Saftig P, Friedrich T. Structural determinants of M-type KCNQ (Kv7) K+ channel assembly. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3757-66. PMID 16597729 DOI: 10.1523/Jneurosci.5017-05.2006 |
0.649 |
|
| 2006 |
Lange PF, Wartosch L, Jentsch TJ, Fuhrmann JC. ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function. Nature. 440: 220-3. PMID 16525474 DOI: 10.1038/Nature04535 |
0.686 |
|
| 2006 |
Kharkovets T, Dedek K, Maier H, Schweizer M, Khimich D, Nouvian R, Vardanyan V, Leuwer R, Moser T, Jentsch TJ. Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness. The Embo Journal. 25: 642-52. PMID 16437162 DOI: 10.1038/Sj.Emboj.7600951 |
0.712 |
|
| 2006 |
Rust MB, Faulhaber J, Budack MK, Pfeffer C, Maritzen T, Didié M, Beck FX, Boettger T, Schubert R, Ehmke H, Jentsch TJ, Hübner CA. Neurogenic mechanisms contribute to hypertension in mice with disruption of the K-Cl cotransporter KCC3. Circulation Research. 98: 549-56. PMID 16424367 DOI: 10.1161/01.Res.0000204449.83861.22 |
0.329 |
|
| 2006 |
Hentschke M, Wiemann M, Hentschke S, Kurth I, Hermans-Borgmeyer I, Seidenbecher T, Jentsch TJ, Gal A, Hübner CA. Mice with a targeted disruption of the Cl-/HCO3- exchanger AE3 display a reduced seizure threshold. Molecular and Cellular Biology. 26: 182-91. PMID 16354689 DOI: 10.1128/Mcb.26.1.182-191.2006 |
0.314 |
|
| 2006 |
Maritzen T, Blanz J, Jentsch T. Physiological Functions of the CLC Chloride Transport Proteins Advances in Molecular and Cell Biology. 38: 9-57. DOI: 10.1016/S1569-2558(06)38002-2 |
0.304 |
|
| 2005 |
Jentsch TJ, Maritzen T, Zdebik AA. Chloride channel diseases resulting from impaired transepithelial transport or vesicular function. The Journal of Clinical Investigation. 115: 2039-46. PMID 16075045 DOI: 10.1172/Jci25470 |
0.45 |
|
| 2005 |
Scheel O, Zdebik AA, Lourdel S, Jentsch TJ. Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins. Nature. 436: 424-7. PMID 16034422 DOI: 10.1038/Nature03860 |
0.459 |
|
| 2005 |
Jentsch TJ, Neagoe I, Scheel O. CLC chloride channels and transporters. Current Opinion in Neurobiology. 15: 319-25. PMID 15913981 DOI: 10.1016/J.Conb.2005.05.002 |
0.472 |
|
| 2005 |
Schenzer A, Friedrich T, Pusch M, Saftig P, Jentsch TJ, Grötzinger J, Schwake M. Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5051-60. PMID 15901787 DOI: 10.1523/Jneurosci.0128-05.2005 |
0.637 |
|
| 2005 |
Jentsch TJ. Chloride transport in the kidney: lessons from human disease and knockout mice. Journal of the American Society of Nephrology : Jasn. 16: 1549-61. PMID 15829707 DOI: 10.1681/Asn.2005020207 |
0.442 |
|
| 2005 |
Pusch M, Jentsch TJ. Unique structure and function of chloride transporting CLC proteins. Ieee Transactions On Nanobioscience. 4: 49-57. PMID 15816171 DOI: 10.1109/Tnb.2004.842503 |
0.403 |
|
| 2005 |
Jentsch TJ, Poët M, Fuhrmann JC, Zdebik AA. Physiological functions of CLC Cl- channels gleaned from human genetic disease and mouse models. Annual Review of Physiology. 67: 779-807. PMID 15709978 DOI: 10.1146/Annurev.Physiol.67.032003.153245 |
0.493 |
|
| 2005 |
Kasper D, Planells-Cases R, Fuhrmann JC, Scheel O, Zeitz O, Ruether K, Schmitt A, Poët M, Steinfeld R, Schweizer M, Kornak U, Jentsch TJ. Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration. The Embo Journal. 24: 1079-91. PMID 15706348 DOI: 10.1038/Sj.Emboj.7600576 |
0.388 |
|
| 2004 |
Jentsch TJ, Hübner CA, Fuhrmann JC. Ion channels: function unravelled by dysfunction. Nature Cell Biology. 6: 1039-47. PMID 15516997 DOI: 10.1038/Ncb1104-1039 |
0.491 |
|
| 2004 |
Huber SM, Duranton C, Henke G, Van De Sand C, Heussler V, Shumilina E, Sandu CD, Tanneur V, Brand V, Kasinathan RS, Lang KS, Kremsner PG, Hübner CA, Rust MB, Dedek K, ... Jentsch TJ, et al. Plasmodium induces swelling-activated ClC-2 anion channels in the host erythrocyte. The Journal of Biological Chemistry. 279: 41444-52. PMID 15272009 DOI: 10.1074/Jbc.M407618200 |
0.721 |
|
| 2004 |
Zdebik AA, Cuffe JE, Bertog M, Korbmacher C, Jentsch TJ. Additional disruption of the ClC-2 Cl(-) channel does not exacerbate the cystic fibrosis phenotype of cystic fibrosis transmembrane conductance regulator mouse models. The Journal of Biological Chemistry. 279: 22276-83. PMID 15007059 DOI: 10.1074/Jbc.M309899200 |
0.493 |
|
| 2004 |
Estévez R, Pusch M, Ferrer-Costa C, Orozco M, Jentsch TJ. Functional and structural conservation of CBS domains from CLC chloride channels. The Journal of Physiology. 557: 363-78. PMID 14724190 DOI: 10.1113/Jphysiol.2003.058453 |
0.443 |
|
| 2004 |
Stein V, Hermans-Borgmeyer I, Jentsch TJ, Hübner CA. Expression of the KCl cotransporter KCC2 parallels neuronal maturation and the emergence of low intracellular chloride. The Journal of Comparative Neurology. 468: 57-64. PMID 14648690 DOI: 10.1002/Cne.10983 |
0.548 |
|
| 2003 |
Boettger T, Rust MB, Maier H, Seidenbecher T, Schweizer M, Keating DJ, Faulhaber J, Ehmke H, Pfeffer C, Scheel O, Lemcke B, Horst J, Leuwer R, Pape HC, Völkl H, ... ... Jentsch TJ, et al. Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold. The Embo Journal. 22: 5422-34. PMID 14532115 DOI: 10.1093/Emboj/Cdg519 |
0.387 |
|
| 2003 |
Estévez R, Schroeder BC, Accardi A, Jentsch TJ, Pusch M. Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1. Neuron. 38: 47-59. PMID 12691663 DOI: 10.1016/S0896-6273(03)00168-5 |
0.4 |
|
| 2003 |
Günther W, Piwon N, Jentsch TJ. The ClC-5 chloride channel knock-out mouse - an animal model for Dent's disease. Pflã¼Gers Archiv : European Journal of Physiology. 445: 456-62. PMID 12548389 DOI: 10.1007/S00424-002-0950-6 |
0.446 |
|
| 2003 |
Schwake M, Jentsch TJ, Friedrich T. A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly. Embo Reports. 4: 76-81. PMID 12524525 DOI: 10.1038/Sj.Embor.Embor715 |
0.563 |
|
| 2002 |
Hübner CA, Jentsch TJ. Ion channel diseases. Human Molecular Genetics. 11: 2435-45. PMID 12351579 DOI: 10.1093/Hmg/11.20.2435 |
0.435 |
|
| 2002 |
Estévez R, Jentsch TJ. CLC chloride channels: correlating structure with function. Current Opinion in Structural Biology. 12: 531-9. PMID 12163078 DOI: 10.1016/S0959-440X(02)00358-5 |
0.473 |
|
| 2002 |
Boettger T, Hübner CA, Maier H, Rust MB, Beck FX, Jentsch TJ. Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4. Nature. 416: 874-8. PMID 11976689 DOI: 10.1038/416874A |
0.397 |
|
| 2002 |
Jentsch TJ, Stein V, Weinreich F, Zdebik AA. Molecular structure and physiological function of chloride channels. Physiological Reviews. 82: 503-68. PMID 11917096 DOI: 10.1152/Physrev.00029.2001 |
0.693 |
|
| 2002 |
Jentsch TJ. Chloride channels are different. Nature. 415: 276-7. PMID 11796992 DOI: 10.1038/415276A |
0.442 |
|
| 2001 |
Estévez R, Boettger T, Stein V, Birkenhäger R, Otto E, Hildebrandt F, Jentsch TJ. Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion. Nature. 414: 558-61. PMID 11734858 DOI: 10.1038/35107099 |
0.673 |
|
| 2001 |
Dedek K, Kunath B, Kananura C, Reuner U, Jentsch TJ, Steinlein OK. Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 98: 12272-7. PMID 11572947 DOI: 10.1073/Pnas.211431298 |
0.748 |
|
| 2001 |
Betz RC, Schoser BG, Kasper D, Ricker K, RamÃrez A, Stein V, Torbergsen T, Lee YA, Nöthen MM, Wienker TF, Malin JP, Propping P, Reis A, Mortier W, Jentsch TJ, et al. Mutations in CAV3 cause mechanical hyperirritability of skeletal muscle in rippling muscle disease. Nature Genetics. 28: 218-9. PMID 11431690 DOI: 10.1038/90050 |
0.528 |
|
| 2001 |
Hübner CA, Stein V, Hermans-Borgmeyer I, Meyer T, Ballanyi K, Jentsch TJ. Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition. Neuron. 30: 515-24. PMID 11395011 DOI: 10.1016/S0896-6273(01)00297-5 |
0.574 |
|
| 2001 |
Bösl MR, Stein V, Hübner C, Zdebik AA, Jordt SE, Mukhopadhyay AK, Davidoff MS, Holstein AF, Jentsch TJ. Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption. The Embo Journal. 20: 1289-99. PMID 11250895 DOI: 10.1093/Emboj/20.6.1289 |
0.805 |
|
| 2001 |
Vandewalle A, Cluzeaud F, Peng KC, Bens M, Lüchow A, Günther W, Jentsch TJ. Tissue distribution and subcellular localization of the ClC-5 chloride channel in rat intestinal cells. American Journal of Physiology. Cell Physiology. 280: C373-81. PMID 11208533 DOI: 10.1152/Ajpcell.2001.280.2.C373 |
0.433 |
|
| 2001 |
Kornak U, Kasper D, Bösl MR, Kaiser E, Schweizer M, Schulz A, Friedrich W, Delling G, Jentsch TJ. Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man. Cell. 104: 205-15. PMID 11207362 DOI: 10.1016/S0092-8674(01)00206-9 |
0.476 |
|
| 2001 |
Stobrawa SM, Breiderhoff T, Takamori S, Engel D, Schweizer M, Zdebik AA, Bösl MR, Ruether K, Jahn H, Draguhn A, Jahn R, Jentsch TJ. Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus. Neuron. 29: 185-96. PMID 11182090 DOI: 10.1016/S0896-6273(01)00189-1 |
0.463 |
|
| 2001 |
Schwake M, Friedrich T, Jentsch TJ. An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease. The Journal of Biological Chemistry. 276: 12049-54. PMID 11116157 DOI: 10.1074/Jbc.M010642200 |
0.635 |
|
| 2001 |
Weinreich F, Jentsch TJ. Pores formed by single subunits in mixed dimers of different CLC chloride channels. The Journal of Biological Chemistry. 276: 2347-53. PMID 11035003 DOI: 10.1074/Jbc.M005733200 |
0.495 |
|
| 2000 |
Jentsch TJ. Neuronal KCNQ potassium channels: physiology and role in disease. Nature Reviews. Neuroscience. 1: 21-30. PMID 11252765 DOI: 10.1038/35036198 |
0.508 |
|
| 2000 |
Piwon N, Günther W, Schwake M, Bösl MR, Jentsch TJ. ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease. Nature. 408: 369-73. PMID 11099045 DOI: 10.1038/35042597 |
0.402 |
|
| 2000 |
Jentsch TJ, Schroeder BC, Kubisch C, Friedrich T, Stein V. Pathophysiology of KCNQ channels: neonatal epilepsy and progressive deafness. Epilepsia. 41: 1068-9. PMID 10961644 DOI: 10.1111/J.1528-1157.2000.Tb00302.X |
0.746 |
|
| 2000 |
Kornak U, Schulz A, Friedrich W, Uhlhaas S, Kremens B, Voit T, Hasan C, Bode U, Jentsch TJ, Kubisch C. Mutations in the a3 subunit of the vacuolar H(+)-ATPase cause infantile malignant osteopetrosis. Human Molecular Genetics. 9: 2059-63. PMID 10942435 DOI: 10.1093/Hmg/9.13.2059 |
0.351 |
|
| 2000 |
Yamamoto K, Cox JP, Friedrich T, Christie PT, Bald M, Houtman PN, Lapsley MJ, Patzer L, Tsimaratos M, Van'T Hoff WG, Yamaoka K, Jentsch TJ, Thakker RV. Characterization of renal chloride channel (CLCN5) mutations in Dent's disease. Journal of the American Society of Nephrology : Jasn. 11: 1460-8. PMID 10906159 |
0.491 |
|
| 2000 |
Waldegger S, Jentsch TJ. From tonus to tonicity: physiology of CLC chloride channels. Journal of the American Society of Nephrology : Jasn. 11: 1331-9. PMID 10864591 |
0.409 |
|
| 2000 |
Weinreich F, Jentsch TJ. Neurological diseases caused by ion-channel mutations. Current Opinion in Neurobiology. 10: 409-15. PMID 10851168 DOI: 10.1016/S0959-4388(00)00089-1 |
0.477 |
|
| 2000 |
Waldegger S, Jentsch TJ. Functional and structural analysis of ClC-K chloride channels involved in renal disease. The Journal of Biological Chemistry. 275: 24527-33. PMID 10831588 DOI: 10.1074/Jbc.M001987200 |
0.508 |
|
| 2000 |
Schroeder BC, Hechenberger M, Weinreich F, Kubisch C, Jentsch TJ. KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents. The Journal of Biological Chemistry. 275: 24089-95. PMID 10816588 DOI: 10.1074/Jbc.M003245200 |
0.475 |
|
| 2000 |
Schwake M, Pusch M, Kharkovets T, Jentsch TJ. Surface expression and single channel properties of KCNQ2/KCNQ3, M-type K+ channels involved in epilepsy. The Journal of Biological Chemistry. 275: 13343-8. PMID 10788442 DOI: 10.1074/Jbc.275.18.13343 |
0.478 |
|
| 2000 |
Kharkovets T, Hardelin JP, Safieddine S, Schweizer M, El-Amraoui A, Petit C, Jentsch TJ. KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway. Proceedings of the National Academy of Sciences of the United States of America. 97: 4333-8. PMID 10760300 DOI: 10.1073/Pnas.97.8.4333 |
0.443 |
|
| 2000 |
Selyanko AA, Hadley JK, Wood IC, Abogadie FC, Jentsch TJ, Brown DA. Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors. The Journal of Physiology. 522: 349-55. PMID 10713961 DOI: 10.1111/J.1469-7793.2000.T01-2-00349.X |
0.419 |
|
| 2000 |
Schroeder BC, Waldegger S, Fehr S, Bleich M, Warth R, Greger R, Jentsch TJ. A constitutively open potassium channel formed by KCNQ1 and KCNE3. Nature. 403: 196-9. PMID 10646604 DOI: 10.1038/35003200 |
0.502 |
|
| 1999 |
Schriever AM, Friedrich T, Pusch M, Jentsch TJ. CLC chloride channels in Caenorhabditis elegans. The Journal of Biological Chemistry. 274: 34238-44. PMID 10567397 DOI: 10.1074/Jbc.274.48.34238 |
0.648 |
|
| 1999 |
Jentsch TJ, Friedrich T, Schriever A, Yamada H. The CLC chloride channel family. Pflã¼Gers Archiv : European Journal of Physiology. 437: 783-95. PMID 10370055 DOI: 10.1007/S004240050847 |
0.645 |
|
| 1999 |
Pusch M, Jordt SE, Stein V, Jentsch TJ. Chloride dependence of hyperpolarization-activated chloride channel gates. The Journal of Physiology. 515: 341-53. PMID 10050002 DOI: 10.1111/J.1469-7793.1999.341Ac.X |
0.828 |
|
| 1999 |
Kubisch C, Schroeder BC, Friedrich T, Lütjohann B, El-Amraoui A, Marlin S, Petit C, Jentsch TJ. KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness. Cell. 96: 437-46. PMID 10025409 DOI: 10.1016/S0092-8674(00)80556-5 |
0.629 |
|
| 1999 |
Friedrich T, Breiderhoff T, Jentsch TJ. Mutational analysis demonstrates that ClC-4 and ClC-5 directly mediate plasma membrane currents. The Journal of Biological Chemistry. 274: 896-902. PMID 9873029 DOI: 10.1074/Jbc.274.2.896 |
0.637 |
|
| 1998 |
Fong P, Rehfeldt A, Jentsch TJ. Determinants of slow gating in ClC-0, the voltage-gated chloride channel of Torpedo marmorata. American Journal of Physiology. Cell Physiology. 274: C966-C973. PMID 29585827 DOI: 10.1152/ajpcell.1998.274.4.C966 |
0.609 |
|
| 1998 |
Schroeder BC, Kubisch C, Stein V, Jentsch TJ. Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy. Nature. 396: 687-90. PMID 9872318 DOI: 10.1038/25367 |
0.686 |
|
| 1998 |
Igarashi T, Günther W, Sekine T, Inatomi J, Shiraga H, Takahashi S, Suzuki J, Tsuru N, Yanagihara T, Shimazu M, Jentsch TJ, Thakker RV. Functional characterization of renal chloride channel, CLCN5, mutations associated with Dent'sJapan disease. Kidney International. 54: 1850-6. PMID 9853249 DOI: 10.1046/J.1523-1755.1998.00203.X |
0.421 |
|
| 1998 |
Steinmeyer K, Jentsch TJ. Molecular physiology of renal chloride channels. Current Opinion in Nephrology and Hypertension. 7: 497-502. PMID 9818195 DOI: 10.1097/00041552-199809000-00003 |
0.464 |
|
| 1998 |
Kubisch C, Schmidt-Rose T, Fontaine B, Bretag AH, Jentsch TJ. ClC-1 chloride channel mutations in myotonia congenita: variable penetrance of mutations shifting the voltage dependence. Human Molecular Genetics. 7: 1753-60. PMID 9736777 DOI: 10.1093/Hmg/7.11.1753 |
0.472 |
|
| 1998 |
Günther W, Lüchow A, Cluzeaud F, Vandewalle A, Jentsch TJ. ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 8075-80. PMID 9653142 DOI: 10.1073/Pnas.95.14.8075 |
0.444 |
|
| 1998 |
Schwappach B, Stobrawa S, Hechenberger M, Steinmeyer K, Jentsch TJ. Golgi localization and functionally important domains in the NH2 and COOH terminus of the yeast CLC putative chloride channel Gef1p. The Journal of Biological Chemistry. 273: 15110-8. PMID 9614122 DOI: 10.1074/Jbc.273.24.15110 |
0.414 |
|
| 1998 |
Fong P, Rehfeldt A, Jentsch TJ. Determinants of slow gating in ClC-0, the voltage-gated chloride channel of Torpedo marmorata. The American Journal of Physiology. 274: C966-73. PMID 9575793 DOI: 10.1152/Ajpcell.1998.274.4.C966 |
0.647 |
|
| 1998 |
Plassart-Schiess E, Gervais A, Eymard B, Lagueny A, Pouget J, Warter JM, Fardeau M, Jentsch TJ, Fontaine B. Novel muscle chloride channel (CLCN1) mutations in myotonia congenita with various modes of inheritance including incomplete dominance and penetrance. Neurology. 50: 1176-9. PMID 9566422 DOI: 10.1212/Wnl.50.4.1176 |
0.393 |
|
| 1998 |
Rychkov GY, Pusch M, Roberts ML, Jentsch TJ, Bretag AH. Permeation and block of the skeletal muscle chloride channel, ClC-1, by foreign anions. The Journal of General Physiology. 111: 653-65. PMID 9565403 DOI: 10.1085/Jgp.111.5.653 |
0.514 |
|
| 1998 |
Clark S, Jordt SE, Jentsch TJ, Mathie A. Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons. The Journal of Physiology. 506: 665-78. PMID 9503329 DOI: 10.1111/J.1469-7793.1998.665Bv.X |
0.759 |
|
| 1998 |
Biervert C, Schroeder BC, Kubisch C, Berkovic SF, Propping P, Jentsch TJ, Steinlein OK. A potassium channel mutation in neonatal human epilepsy. Science (New York, N.Y.). 279: 403-6. PMID 9430594 DOI: 10.1126/Science.279.5349.403 |
0.461 |
|
| 1997 |
Wollnik B, Schroeder BC, Kubisch C, Esperer HD, Wieacker P, Jentsch TJ. Pathophysiological mechanisms of dominant and recessive KVLQT1 K+ channel mutations found in inherited cardiac arrhythmias. Human Molecular Genetics. 6: 1943-9. PMID 9302275 DOI: 10.1093/Hmg/6.11.1943 |
0.487 |
|
| 1997 |
Lloyd SE, Gunther W, Pearce SH, Thomson A, Bianchi ML, Bosio M, Craig IW, Fisher SE, Scheinman SJ, Wrong O, Jentsch TJ, Thakker RV. Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders. Human Molecular Genetics. 6: 1233-9. PMID 9259268 DOI: 10.1093/Hmg/6.8.1233 |
0.436 |
|
| 1997 |
Schmidt-Rose T, Jentsch TJ. Reconstitution of functional voltage-gated chloride channels from complementary fragments of CLC-1. The Journal of Biological Chemistry. 272: 20515-21. PMID 9252364 DOI: 10.1074/Jbc.272.33.20515 |
0.432 |
|
| 1997 |
Ludewig U, Pusch M, Jentsch TJ. Independent gating of single pores in CLC-0 chloride channels. Biophysical Journal. 73: 789-97. PMID 9251795 DOI: 10.1016/S0006-3495(97)78111-6 |
0.491 |
|
| 1997 |
Ludewig U, Jentsch TJ, Pusch M. Inward rectification in ClC-0 chloride channels caused by mutations in several protein regions. The Journal of General Physiology. 110: 165-71. PMID 9236209 DOI: 10.1085/Jgp.110.2.165 |
0.485 |
|
| 1997 |
Schmidt-Rose T, Jentsch TJ. Transmembrane topology of a CLC chloride channel. Proceedings of the National Academy of Sciences of the United States of America. 94: 7633-8. PMID 9207144 DOI: 10.1073/Pnas.94.14.7633 |
0.457 |
|
| 1997 |
Vandewalle A, Cluzeaud F, Bens M, Kieferle S, Steinmeyer K, Jentsch TJ. Localization and induction by dehydration of ClC-K chloride channels in the rat kidney. The American Journal of Physiology. 272: F678-88. PMID 9176380 DOI: 10.1152/Ajprenal.1997.272.5.F678 |
0.397 |
|
| 1997 |
Jordt SE, Jentsch TJ. Molecular dissection of gating in the ClC-2 chloride channel. The Embo Journal. 16: 1582-92. PMID 9130703 DOI: 10.1093/Emboj/16.7.1582 |
0.804 |
|
| 1997 |
Lloyd SE, Pearce SH, Günther W, Kawaguchi H, Igarashi T, Jentsch TJ, Thakker RV. Idiopathic low molecular weight proteinuria associated with hypercalciuric nephrocalcinosis in Japanese children is due to mutations of the renal chloride channel (CLCN5). The Journal of Clinical Investigation. 99: 967-74. PMID 9062355 DOI: 10.1172/Jci119262 |
0.385 |
|
| 1997 |
Ludewig U, Jentsch TJ, Pusch M. Analysis of a protein region involved in permeation and gating of the voltage-gated Torpedo chloride channel ClC-0. The Journal of Physiology. 498: 691-702. PMID 9051580 DOI: 10.1113/Jphysiol.1997.Sp021893 |
0.504 |
|
| 1997 |
Jentsch TJ, Günther W. Chloride channels: an emerging molecular picture. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 19: 117-26. PMID 9046241 DOI: 10.1002/Bies.950190206 |
0.531 |
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| 1997 |
Pusch M, Ludewig U, Jentsch TJ. Temperature dependence of fast and slow gating relaxations of ClC-0 chloride channels. The Journal of General Physiology. 109: 105-16. PMID 8997669 DOI: 10.1085/Jgp.109.1.105 |
0.439 |
|
| 1997 |
Jentsch TJ. CLC chloride channels in human disease Faseb Journal. 11: A998. |
0.322 |
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| 1996 |
Hechenberger M, Schwappach B, Fischer WN, Frommer WB, Jentsch TJ, Steinmeyer K. A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption. The Journal of Biological Chemistry. 271: 33632-8. PMID 8969232 DOI: 10.1074/Jbc.271.52.33632 |
0.421 |
|
| 1996 |
Rychkov GY, Pusch M, Astill DS, Roberts ML, Jentsch TJ, Bretag AH. Concentration and pH dependence of skeletal muscle chloride channel ClC-1. The Journal of Physiology. 497: 423-35. PMID 8961185 DOI: 10.1113/Jphysiol.1996.Sp021778 |
0.467 |
|
| 1996 |
Lorenz C, Pusch M, Jentsch TJ. Heteromultimeric CLC chloride channels with novel properties. Proceedings of the National Academy of Sciences of the United States of America. 93: 13362-6. PMID 8917596 DOI: 10.1073/Pnas.93.23.13362 |
0.485 |
|
| 1996 |
Ludewig U, Pusch M, Jentsch TJ. Two physically distinct pores in the dimeric ClC-0 chloride channel. Nature. 383: 340-3. PMID 8848047 DOI: 10.1038/383340A0 |
0.524 |
|
| 1996 |
Staley K, Smith R, Schaack J, Wilcox C, Jentsch TJ. Alteration of GABAA receptor function following gene transfer of the CLC-2 chloride channel. Neuron. 17: 543-51. PMID 8816717 DOI: 10.1016/S0896-6273(00)80186-5 |
0.433 |
|
| 1996 |
Jentsch TJ. Chloride channels: a molecular perspective. Current Opinion in Neurobiology. 6: 303-10. PMID 8794080 DOI: 10.1016/S0959-4388(96)80112-7 |
0.522 |
|
| 1996 |
Lloyd SE, Pearce SH, Fisher SE, Steinmeyer K, Schwappach B, Scheinman SJ, Harding B, Bolino A, Devoto M, Goodyer P, Rigden SP, Wrong O, Jentsch TJ, Craig IW, Thakker RV. A common molecular basis for three inherited kidney stone diseases. Nature. 379: 445-9. PMID 8559248 DOI: 10.1038/379445A0 |
0.341 |
|
| 1996 |
Steinmeyer K, Jentsch TJ. REVIEW ■ : Chloride Channel Myotonias The Neuroscientist. 2: 225-232. DOI: 10.1177/107385849600200411 |
0.457 |
|
| 1996 |
Steinmeyer K, Jentsch TJ. Chloride channel myotonias Neuroscientist. 2: 225-232. |
0.376 |
|
| 1995 |
Pusch M, Steinmeyer K, Koch MC, Jentsch TJ. Mutations in dominant human myotonia congenita drastically alter the voltage dependence of the CIC-1 chloride channel. Neuron. 15: 1455-63. PMID 8845168 DOI: 10.1016/0896-6273(95)90023-3 |
0.49 |
|
| 1995 |
Brandt S, Jentsch TJ. ClC-6 and ClC-7 are two novel broadly expressed members of the CLC chloride channel family. Febs Letters. 377: 15-20. PMID 8543009 DOI: 10.1016/0014-5793(95)01298-2 |
0.404 |
|
| 1995 |
Steinmeyer K, Schwappach B, Bens M, Vandewalle A, Jentsch TJ. Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease. The Journal of Biological Chemistry. 270: 31172-7. PMID 8537381 DOI: 10.1074/Jbc.270.52.31172 |
0.424 |
|
| 1995 |
Lengeling A, Gronemeier M, Ronsiek M, Thiemann A, Jentsch TJ, Jockusch H. Chloride channel 2 gene (Clc2) maps to chromosome 16 of the mouse, extending a region of conserved synteny with human chromosome 3q. Genetical Research. 66: 175-8. PMID 8522159 DOI: 10.1017/S0016672300034522 |
0.4 |
|
| 1995 |
Pusch M, Ludewig U, Rehfeldt A, Jentsch TJ. Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion. Nature. 373: 527-31. PMID 7845466 DOI: 10.1038/373527A0 |
0.519 |
|
| 1995 |
Jentsch TJ, Günther W, Pusch M, Schwappach B. Properties of voltage-gated chloride channels of the ClC gene family. The Journal of Physiology. 482: 19S-25S. PMID 7730971 DOI: 10.1113/Jphysiol.1995.Sp020560 |
0.508 |
|
| 1995 |
Jentsch TJ, Lorenz C, Pusch M, Steinmeyer K. Myotonias due to CLC-1 chloride channel mutations. Society of General Physiologists Series. 50: 149-59. PMID 7676320 |
0.372 |
|
| 1995 |
Fong P, Jentsch TJ. Molecular basis of epithelial Cl channels. The Journal of Membrane Biology. 144: 189-97. PMID 7658457 DOI: 10.1007/Bf00236832 |
0.677 |
|
| 1995 |
Jentsch TJ. S-6-3 Analysis of CLC-1 chloride channel mutations causing myotonia Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control. 97: S13-S14. DOI: 10.1016/0924-980X(95)92466-Y |
0.356 |
|
| 1994 |
Pusch M, Steinmeyer K, Jentsch TJ. Low single channel conductance of the major skeletal muscle chloride channel, ClC-1. Biophysical Journal. 66: 149-52. PMID 8130334 DOI: 10.1016/S0006-3495(94)80753-2 |
0.477 |
|
| 1994 |
Gronemeier M, Condie A, Prosser J, Steinmeyer K, Jentsch TJ, Jockusch H. Nonsense and missense mutations in the muscular chloride channel gene Clc-1 of myotonic mice. The Journal of Biological Chemistry. 269: 5963-7. PMID 8119941 |
0.338 |
|
| 1994 |
Steinmeyer K, Lorenz C, Pusch M, Koch MC, Jentsch TJ. Multimeric structure of ClC-1 chloride channel revealed by mutations in dominant myotonia congenita (Thomsen). The Embo Journal. 13: 737-43. PMID 8112288 DOI: 10.1002/J.1460-2075.1994.Tb06315.X |
0.505 |
|
| 1994 |
Kieferle S, Fong P, Bens M, Vandewalle A, Jentsch TJ. Two highly homologous members of the ClC chloride channel family in both rat and human kidney. Proceedings of the National Academy of Sciences of the United States of America. 91: 6943-7. PMID 8041726 DOI: 10.1073/Pnas.91.15.6943 |
0.611 |
|
| 1994 |
Jentsch TJ. Molecular physiology of anion channels. Current Opinion in Cell Biology. 6: 600-6. PMID 7986538 DOI: 10.1016/0955-0674(94)90082-5 |
0.521 |
|
| 1994 |
Lorenz C, Meyer-Kleine C, Steinmeyer K, Koch MC, Jentsch TJ. Genomic organization of the human muscle chloride channel CIC-1 and analysis of novel mutations leading to Becker-type myotonia. Human Molecular Genetics. 3: 941-6. PMID 7951242 DOI: 10.1093/Hmg/3.6.941 |
0.44 |
|
| 1994 |
Pusch M, Jentsch TJ. Molecular physiology of voltage-gated chloride channels. Physiological Reviews. 74: 813-27. PMID 7938226 DOI: 10.1152/Physrev.1994.74.4.813 |
0.471 |
|
| 1994 |
Jentsch TJ. Structure and function of ClC chloride channels. The Japanese Journal of Physiology. 44: S1-2. PMID 7752510 |
0.341 |
|
| 1994 |
Jentsch TJ. Trinity of cation channels. Nature. 367: 412-3. PMID 7509038 DOI: 10.1038/367412A0 |
0.471 |
|
| 1994 |
Jentsch TJ. Molecular biology of voltage-gated chloride channels Current Topics in Membranes. 42: 35-57. DOI: 10.1016/S0070-2161(08)60817-5 |
0.514 |
|
| 1993 |
Jentsch TJ, Pusch M, Rehfeldt A, Steinmeyer K. The ClC family of voltage-gated chloride channels: structure and function. Annals of the New York Academy of Sciences. 707: 285-93. PMID 9137559 DOI: 10.1111/J.1749-6632.1993.Tb38059.X |
0.451 |
|
| 1993 |
Jentsch TJ. Chloride channels. Current Opinion in Neurobiology. 3: 316-21. PMID 8396475 DOI: 10.1016/0959-4388(93)90123-G |
0.414 |
|
| 1993 |
Jentsch TJ. Recessive and dominant human myotonias are due to mutations of a chloride channel Biomedicine and Pharmacotherapy. 47: 112. DOI: 10.1016/0753-3322(93)90304-4 |
0.459 |
|
| 1992 |
Koch MC, Steinmeyer K, Lorenz C, Ricker K, Wolf F, Otto M, Zoll B, Lehmann-Horn F, Grzeschik KH, Jentsch TJ. The skeletal muscle chloride channel in dominant and recessive human myotonia. Science (New York, N.Y.). 257: 797-800. PMID 1379744 DOI: 10.1126/Science.1379744 |
0.378 |
|
| 1992 |
Gründer S, Thiemann A, Pusch M, Jentsch TJ. Regions involved in the opening of CIC-2 chloride channel by voltage and cell volume. Nature. 360: 759-62. PMID 1334533 DOI: 10.1038/360759A0 |
0.519 |
|
| 1992 |
Thiemann A, Gründer S, Pusch M, Jentsch TJ. A chloride channel widely expressed in epithelial and non-epithelial cells. Nature. 356: 57-60. PMID 1311421 DOI: 10.1038/356057A0 |
0.542 |
|
| 1991 |
Bauer CK, Steinmeyer K, Schwarz JR, Jentsch TJ. Completely functional double-barreled chloride channel expressed from a single Torpedo cDNA. Proceedings of the National Academy of Sciences of the United States of America. 88: 11052-6. PMID 1722317 DOI: 10.1073/Pnas.88.24.11052 |
0.516 |
|
| 1991 |
Steinmeyer K, Klocke R, Ortland C, Gronemeier M, Jockusch H, Gründer S, Jentsch TJ. Inactivation of muscle chloride channel by transposon insertion in myotonic mice. Nature. 354: 304-8. PMID 1659665 DOI: 10.1038/354304A0 |
0.407 |
|
| 1991 |
Steinmeyer K, Ortland C, Jentsch TJ. Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel. Nature. 354: 301-4. PMID 1659664 DOI: 10.1038/354301A0 |
0.423 |
|
| 1990 |
Jentsch TJ, Steinmeyer K, Schwarz G. Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes. Nature. 348: 510-4. PMID 2174129 DOI: 10.1038/348510A0 |
0.46 |
|
| 1990 |
Wiederholt M, Jentsch TJ. Cell culture of bovine corneal endothelial cells and its application to transport studies. Methods in Enzymology. 192: 571-82. PMID 2074807 DOI: 10.1016/0076-6879(90)92095-U |
0.601 |
|
| 1989 |
Jentsch TJ, Garcia AM, Lodish HF. Primary structure of a novel 4-acetamido-4'-isothiocyanostilbene-2,2'-disulphonic acid (SITS)-binding membrane protein highly expressed in Torpedo californica electroplax. The Biochemical Journal. 261: 155-66. PMID 2775201 DOI: 10.1042/Bj2610155 |
0.383 |
|
| 1988 |
Jentsch TJ, Korbmacher C, Janicke I, Fischer DG, Stahl F, Helbig H, Hollwede H, Cragoe EJ, Keller SK, Wiederholt M. Regulation of cytoplasmic pH of cultured bovine corneal endothelial cells in the absence and presence of bicarbonate. The Journal of Membrane Biology. 103: 29-40. PMID 3184169 DOI: 10.1007/Bf01871930 |
0.627 |
|
| 1988 |
Keller SK, Jentsch TJ, Janicke I, Wiederholt M. Regulation of intracellular pH in cultured bovine retinal pigment epithelial cells. Pflã¼Gers Archiv : European Journal of Physiology. 411: 47-52. PMID 2832823 DOI: 10.1007/Bf00581645 |
0.624 |
|
| 1986 |
Keller SK, Jentsch TJ, Koch M, Wiederholt M. Interactions of pH and K+ conductance in cultured bovine retinal pigment epithelial cells. The American Journal of Physiology. 250: C124-37. PMID 3942203 DOI: 10.1152/Ajpcell.1986.250.1.C124 |
0.609 |
|
| 1986 |
Jentsch TJ, Matthes H, Keller SK, Wiederholt M. Electrical properties of sodium bicarbonate symport in kidney epithelial cells (BSC-1). The American Journal of Physiology. 251: F954-68. PMID 3024506 DOI: 10.1152/Ajprenal.1986.251.6.F954 |
0.643 |
|
| 1985 |
Jentsch TJ, von der Haar B, Keller SK, Wiederholt M. Response of the intracellular potentials of cultured bovine lens cells to ions and inhibitors. Experimental Eye Research. 41: 131-44. PMID 4065242 DOI: 10.1016/0014-4835(85)90018-1 |
0.626 |
|
| 1985 |
Jentsch TJ, Keller SK, Wiederholt M. Ion transport mechanisms in cultured bovine corneal endothelial cells. Current Eye Research. 4: 361-9. PMID 4017631 DOI: 10.3109/02713688509025149 |
0.625 |
|
| 1985 |
Jentsch TJ, Matthes H, Keller SK, Wiederholt M. Anion dependence of electrical effects of bicarbonate and sodium on cultured bovine corneal endothelial cells. Pflã¼Gers Archiv : European Journal of Physiology. 403: 175-85. PMID 3982968 DOI: 10.1007/Bf00584097 |
0.643 |
|
| 1985 |
Wiederholt M, Jentsch TJ, Keller SK. Electrogenic sodium-bicarbonate symport in cultured corneal endothelial cells. Pflã¼Gers Archiv : European Journal of Physiology. 405: S167-71. PMID 3003668 DOI: 10.1007/Bf00581801 |
0.617 |
|
| 1984 |
Jentsch TJ, Keller SK, Koch M, Wiederholt M. Evidence for coupled transport of bicarbonate and sodium in cultured bovine corneal endothelial cells. The Journal of Membrane Biology. 81: 189-204. PMID 6502693 DOI: 10.1007/Bf01868713 |
0.629 |
|
| 1984 |
Wiederholt M, Keller S, Krolik A, Jentsch TJ. The calcium antagonist nisoldipine stimulates the electrolyte transport of the isolated frog skin. Biochemical Pharmacology. 33: 2926-8. PMID 6332628 DOI: 10.1016/0006-2952(84)90219-3 |
0.552 |
|
| 1984 |
Jentsch TJ, Koch M, Bleckmann H, Wiederholt M. Effect of bicarbonate, pH, methazolamide and stilbenes on the intracellular potentials of cultured bovine corneal endothelial cells. The Journal of Membrane Biology. 78: 103-17. PMID 6325699 DOI: 10.1007/Bf01869198 |
0.631 |
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