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Pierre Chambon - Publications

Affiliations: 
1968-1993 Faculté de Médecine de Strasbourg Université Louis Pasteur 
 1993-2002 Collège de France, Paris, Île-de-France, France 
Website:
http://www.usias.fr/en/chairs/pierre-chambon/
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Year Citation  Score
2020 Adlanmerini M, Chanaelle F, Zahreddine R, Vessières E, Buscato M, Solinhac R, Favre J, Anquetil T, Guihot AL, Boudou F, Raymond-Letron I, Chambon P, Gourdy P, Ohlsson C, Laurell H, et al. Mutation of Arginine 264 on ERα (Estrogen Receptor Alpha) Selectively Abrogates the Rapid Signaling of Estradiol in the Endothelium Without Altering Fertility. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314159. PMID 32640903 DOI: 10.1161/Atvbaha.120.314159  0.359
2020 Gustafsson KL, Farman HH, Henning P, Lionikaite V, Movérare-Skrtic S, Sjogren K, Andersson A, Islander U, Bernardi AI, Chambon P, Ohlsson C, Lagerquist MK. SUN-744 Phosphorylation Site S122 in Estrogen Receptor α Has a Tissue-Dependent Role in Female Mice Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.876  0.302
2019 Hua G, Zein N, Paulen L, Chambon P. The glucocorticoid receptor agonistic modulators CpdX and CpdX-D3 do not generate the debilitating effects of synthetic glucocorticoids. Proceedings of the National Academy of Sciences of the United States of America. PMID 31221758 DOI: 10.1073/Pnas.1908264116  0.308
2019 Oakley RH, Cruz-Topete D, He B, Foley JF, Myers PH, Xu X, Gomez-Sanchez CE, Chambon P, Willis MS, Cidlowski JA. Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice. Science Signaling. 12. PMID 30992401 DOI: 10.1126/Scisignal.Aau9685  0.307
2017 Andersson A, Törnqvist AE, Movérare-Skrtic S, Bernardi AI, Farman HH, Chambon P, Engdahl C, Lagerquist MK, Windahl SH, Carlsten H, Ohlsson C, Islander U. Roles of activating functions 1 and 2 of estrogen receptor α in lymphopoiesis. The Journal of Endocrinology. PMID 29255084 DOI: 10.1530/Joe-17-0372  0.341
2017 Vieira JM, Howard S, Villa Del Campo C, Bollini S, Dubé KN, Masters M, Barnette DN, Rohling M, Sun X, Hankins LE, Gavriouchkina D, Williams R, Metzger D, Chambon P, Sauka-Spengler T, et al. BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease. Nature Communications. 8: 16034. PMID 28737171 DOI: 10.1038/Ncomms16034  0.38
2017 Ganti KP, Mukherji A, Surjit M, Li M, Chambon P. Similarities and differences in the transcriptional control of expression of the mouse TSLP gene in skin epidermis and intestinal epithelium. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115699 DOI: 10.1073/Pnas.1620697114  0.42
2017 Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, His TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, ... ... Chambon P, et al. Regeneration of fat cells from myofibroblasts during wound healing. Science (New York, N.Y.). PMID 28059714 DOI: 10.1126/Science.Aai8792  0.339
2016 Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. The Journal of Clinical Investigation. PMID 27820702 DOI: 10.1172/Jci86359  0.308
2016 Börjesson AE, Farman HH, Movérare-Skrtic S, Engdahl C, Antal MC, Koskela A, Tuukkanen J, Carlsten H, Krust A, Chambon P, Sjögren K, Lagerquist MK, Windahl SH, Ohlsson C. SERMs have substance specific effects on bone and these effects are mediated via ERαAF-1 in female mice. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00488.2015. PMID 27048997 DOI: 10.1152/Ajpendo.00488.2015  0.338
2015 Hua G, Ganti KP, Chambon P. Glucocorticoid-induced tethered transrepression requires SUMOylation of GR and formation of a SUMO-SMRT/NCoR1-HDAC3 repressing complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 26712006 DOI: 10.1073/Pnas.1522826113  0.378
2015 Hua G, Paulen L, Chambon P. GR SUMOylation and formation of an SUMO-SMRT/NCoR1-HDAC3 repressing complex is mandatory for GC-induced IR nGRE-mediated transrepression. Proceedings of the National Academy of Sciences of the United States of America. PMID 26712002 DOI: 10.1073/Pnas.1522821113  0.392
2015 Mukherji A, Kobiita A, Chambon P. Shifting the feeding of mice to the rest phase creates metabolic alterations, which, on their own, shift the peripheral circadian clocks by 12 hours. Proceedings of the National Academy of Sciences of the United States of America. 112: E6683-90. PMID 26627259 DOI: 10.1073/Pnas.1519735112  0.343
2015 Valéra MC, Fontaine C, Lenfant F, Cabou C, Guillaume M, Smirnova N, Kim SH, Chambon P, Katzenellenbogen JA, Katzenellenbogen BS, Payrastre B, Arnal JF. Protective Hematopoietic Effect of Estrogens in a Mouse Model of Thrombosis: Respective Roles of Nuclear Versus Membrane Estrogen Receptor α. Endocrinology. 156: 4293-301. PMID 26280130 DOI: 10.1210/En.2015-1522  0.336
2015 Gao L, Rabbitt EH, Condon JC, Renthal NE, Johnston JM, Mitsche MA, Chambon P, Xu J, O'Malley BW, Mendelson CR. Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. The Journal of Clinical Investigation. 125: 2808-24. PMID 26098214 DOI: 10.1172/Jci78544  0.356
2015 Nakajima T, Tanimoto Y, Tanaka M, Chambon P, Watanabe H, Iguchi T, Sato T. Neonatal estrogen receptor β is important in the permanent inhibition of epithelial cell proliferation in the mouse uterus. Endocrinology. en20151012. PMID 26020796 DOI: 10.1210/En.2015-1012  0.353
2014 Murakami G, Hojo Y, Ogiue-Ikeda M, Mukai H, Chambon P, Nakajima K, Ooishi Y, Kimoto T, Kawato S. Estrogen receptor KO mice study on rapid modulation of spines and long-term depression in the hippocampus. Brain Research. PMID 25498865 DOI: 10.1016/J.Brainres.2014.12.002  0.304
2014 Engdahl C, Börjesson AE, Forsman HF, Andersson A, Stubelius A, Krust A, Chambon P, Islander U, Ohlsson C, Carlsten H, Lagerquist MK. The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on arthritis. Arthritis Research & Therapy. 16: R150. PMID 25028072 DOI: 10.1186/Ar4612  0.345
2014 Benbrook DM, Chambon P, Rochette-Egly C, Asson-Batres MA. History of retinoic acid receptors. Sub-Cellular Biochemistry. 70: 1-20. PMID 24962878 DOI: 10.1007/978-94-017-9050-5_1  0.421
2014 Campbell L, Emmerson E, Williams H, Saville CR, Krust A, Chambon P, Mace KA, Hardman MJ. Estrogen receptor-alpha promotes alternative macrophage activation during cutaneous repair. The Journal of Investigative Dermatology. 134: 2447-57. PMID 24769859 DOI: 10.1038/Jid.2014.175  0.311
2014 Cheong RY, Porteous R, Chambon P, Abrahám I, Herbison AE. Effects of neuron-specific estrogen receptor (ER) α and ERβ deletion on the acute estrogen negative feedback mechanism in adult female mice. Endocrinology. 155: 1418-27. PMID 24476134 DOI: 10.1210/En.2013-1943  0.313
2014 Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot AL, Boudou F, Sautier L, Vessières E, Kim SH, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, et al. Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions. Proceedings of the National Academy of Sciences of the United States of America. 111: E283-90. PMID 24371309 DOI: 10.1073/Pnas.1322057111  0.339
2014 Mardaryev AN, Gdula MR, Yarker JL, Emelianov VU, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Joffe B, Solovei I, Chambon P, Botchkarev VA, Fessing MY. p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development (Cambridge, England). 141: 101-11. PMID 24346698 DOI: 10.1242/Dev.103200  0.381
2014 Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot A, Boudou F, Sautier L, Vessieres E, Kim S, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, et al. 0053: The estrogen receptor alpha C451 palmitoylation site is absolutely required for vascular membrane-initiated action of estrogens in mice Archives of Cardiovascular Diseases Supplements. 6: 58-59. DOI: 10.1016/S1878-6480(14)71424-7  0.354
2014 Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Boudou F, Kim S, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen J, Gourdy P, Shaul P, Henrion D, et al. Mutation of palmitoylation site of Estrogen Receptor ER alpha in vivo reveals tissue-specific roles for membrane versus genomic effects of estrogens Annales D'Endocrinologie. 75: 270. DOI: 10.1016/J.Ando.2014.07.062  0.375
2013 Szatkowski C, Vallet J, Dormishian M, Messaddeq N, Valet P, Boulberdaa M, Metzger D, Chambon P, Nebigil CG. Prokineticin receptor 1 as a novel suppressor of preadipocyte proliferation and differentiation to control obesity. Plos One. 8: e81175. PMID 24324673 DOI: 10.1371/Journal.Pone.0081175  0.33
2013 Handgraaf S, Riant E, Fabre A, Waget A, Burcelin R, Lière P, Krust A, Chambon P, Arnal JF, Gourdy P. Prevention of obesity and insulin resistance by estrogens requires ERα activation function-2 (ERαAF-2), whereas ERαAF-1 is dispensable. Diabetes. 62: 4098-108. PMID 23903353 DOI: 10.2337/Db13-0282  0.312
2013 Mukherji A, Kobiita A, Ye T, Chambon P. Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs. Cell. 153: 812-27. PMID 23663780 DOI: 10.1016/J.Cell.2013.04.020  0.306
2013 Seillet C, Rouquié N, Foulon E, Douin-Echinard V, Krust A, Chambon P, Arnal JF, Guéry JC, Laffont S. Estradiol promotes functional responses in inflammatory and steady-state dendritic cells through differential requirement for activation function-1 of estrogen receptor α. Journal of Immunology (Baltimore, Md. : 1950). 190: 5459-70. PMID 23626011 DOI: 10.4049/Jimmunol.1203312  0.331
2013 Sekiya T, Kashiwagi I, Yoshida R, Fukaya T, Morita R, Kimura A, Ichinose H, Metzger D, Chambon P, Yoshimura A. Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis. Nature Immunology. 14: 230-7. PMID 23334790 DOI: 10.1038/Ni.2520  0.34
2013 Windahl SH, Saxon L, Börjesson AE, Lagerquist MK, Frenkel B, Henning P, Lerner UH, Galea GL, Meakin LB, Engdahl C, Sjögren K, Antal MC, Krust A, Chambon P, Lanyon LE, et al. Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 291-301. PMID 22972752 DOI: 10.1002/Jbmr.1754  0.309
2012 Cammas F, Khetchoumian K, Chambon P, Losson R. TRIM involvement in transcriptional regulation. Advances in Experimental Medicine and Biology. 770: 59-76. PMID 23631000 DOI: 10.1007/978-1-4614-5398-7_5  0.344
2012 Nadra K, Médard JJ, Mul JD, Han GS, Grès S, Pende M, Metzger D, Chambon P, Cuppen E, Saulnier-Blache JS, Carman GM, Desvergne B, Chrast R. Cell autonomous lipin 1 function is essential for development and maintenance of white and brown adipose tissue. Molecular and Cellular Biology. 32: 4794-810. PMID 23028044 DOI: 10.1128/Mcb.00512-12  0.354
2012 Raverdeau M, Gely-Pernot A, Féret B, Dennefeld C, Benoit G, Davidson I, Chambon P, Mark M, Ghyselinck NB. Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 16582-7. PMID 23012458 DOI: 10.1073/Pnas.1214936109  0.326
2012 Mori M, Gargowitsch L, Bornert JM, Garnier JM, Mark M, Chambon P, Metzger D. Temporally controlled targeted somatic mutagenesis in mouse eye pigment epithelium. Genesis (New York, N.Y. : 2000). 50: 828-32. PMID 22730183 DOI: 10.1002/Dvg.22044  0.33
2012 Sanchez-Fernandez MA, Sbacchi S, Correa-Tapia M, Naumann R, Klemm J, Chambon P, Al-Robaiy S, Blessing M, Hoflack B. Transgenic mice for a tamoxifen-induced, conditional expression of the Cre recombinase in osteoclasts. Plos One. 7: e37592. PMID 22624050 DOI: 10.1371/Journal.Pone.0037592  0.361
2012 Kakuta H, Tanaka M, Chambon P, Watanabe H, Iguchi T, Sato T. Involvement of gonadotropins in the induction of hypertrophy-hyperplasia in the interstitial tissues of ovaries in neonatally diethylstilbestrol-treated mice. Reproductive Toxicology (Elmsford, N.Y.). 33: 35-44. PMID 22100434 DOI: 10.1016/J.Reprotox.2011.10.013  0.302
2012 Arnal JF, Lenfant F, Flouriot G, Tremollières F, Laurell H, Fontaine C, Krust A, Chambon P, Gourdy P. From in vivo gene targeting of oestrogen receptors to optimization of their modulation in menopause. British Journal of Pharmacology. 165: 57-66. PMID 21671899 DOI: 10.1111/J.1476-5381.2011.01538.X  0.326
2012 Engdahl C, Börjesson AE, Andersson A, Stubelius A, Krust A, Chambon P, Islander U, Ohlsson C, Carlsten H, Lagerquist MK. Estrogen receptor α (ERα) expression in cartilage is important for the ameliorating effects of estrogen on synovitis, but not joint destruction. Annals of the Rheumatic Diseases. 71. DOI: 10.1136/Annrheumdis-2011-201237.2  0.338
2012 Lagerquist MK, Engdahl C, Börjesson AE, Andersson A, Stubelius A, Krust A, Chambon P, Islander U, Ohlsson C, Carlsten H. Estrogen receptor alpha expression in cartilage is important for the ameliorating effects of estrogen on synovitis, but not joint destruction Bone. 50. DOI: 10.1016/J.Bone.2012.02.178  0.309
2012 Börjesson AE, Windahl SH, Karimian E, Eriksson EE, Lagerquist MK, Engdahl C, Antal MC, Krust A, Chambon P, Sävendahl L, Ohlsson C. The role of estrogen receptor-αlpha and its activation function 1 (af-1) for growth plate closure in female mice Bone. 50. DOI: 10.1016/J.Bone.2012.02.163  0.328
2011 Metzger D, Chambon P. Generation of Spatio-Temporally Controlled Targeted Somatic Mutations in the Mouse. Current Protocols in Mouse Biology. 1: 55-70. PMID 26068987 DOI: 10.1002/9780470942390.Mo100128  0.331
2011 Hensler M, Bardova K, Jilkova ZM, Wahli W, Meztger D, Chambon P, Kopecky J, Flachs P. The inhibition of fat cell proliferation by n-3 fatty acids in dietary obese mice. Lipids in Health and Disease. 10: 128. PMID 21810216 DOI: 10.1186/1476-511X-10-128  0.303
2011 Billon-Galés A, Krust A, Fontaine C, Abot A, Flouriot G, Toutain C, Berges H, Gadeau AP, Lenfant F, Gourdy P, Chambon P, Arnal JF. Activation function 2 (AF2) of estrogen receptor-alpha is required for the atheroprotective action of estradiol but not to accelerate endothelial healing. Proceedings of the National Academy of Sciences of the United States of America. 108: 13311-6. PMID 21788522 DOI: 10.1073/Pnas.1105632108  0.306
2011 Tisserand J, Khetchoumian K, Thibault C, Dembélé D, Chambon P, Losson R. Tripartite motif 24 (Trim24/Tif1α) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor α (Rarα) inhibition. The Journal of Biological Chemistry. 286: 33369-79. PMID 21768647 DOI: 10.1074/Jbc.M111.225680  0.359
2011 Kim HJ, Gieske MC, Trudgen KL, Hudgins-Spivey S, Kim BG, Krust A, Chambon P, Jeong JW, Blalock E, Ko C. Identification of estradiol/ERα-regulated genes in the mouse pituitary. The Journal of Endocrinology. 210: 309-21. PMID 21700660 DOI: 10.1530/Joe-11-0098  0.357
2011 Surjit M, Ganti KP, Mukherji A, Ye T, Hua G, Metzger D, Li M, Chambon P. Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor. Cell. 145: 224-41. PMID 21496643 DOI: 10.1016/J.Cell.2011.03.027  0.36
2011 Sekiya T, Kashiwagi I, Inoue N, Morita R, Hori S, Waldmann H, Rudensky AY, Ichinose H, Metzger D, Chambon P, Yoshimura A. The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells. Nature Communications. 2: 269. PMID 21468021 DOI: 10.1038/Ncomms1272  0.323
2011 Wietrzych-Schindler M, Szyszka-Niagolov M, Ohta K, Endo Y, Pérez E, de Lera AR, Chambon P, Krezel W. Retinoid x receptor gamma is implicated in docosahexaenoic acid modulation of despair behaviors and working memory in mice. Biological Psychiatry. 69: 788-94. PMID 21334601 DOI: 10.1016/J.Biopsych.2010.12.017  0.678
2011 Della Torre S, Rando G, Meda C, Stell A, Chambon P, Krust A, Ibarra C, Magni P, Ciana P, Maggi A. Amino acid-dependent activation of liver estrogen receptor alpha integrates metabolic and reproductive functions via IGF-1. Cell Metabolism. 13: 205-14. PMID 21284987 DOI: 10.1016/J.Cmet.2011.01.002  0.327
2011 Yadav VK, Oury F, Tanaka KF, Tanaka K, Thomas T, Wang Y, Cremers S, Hen R, Krust A, Chambon P, Karsenty G. Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications. The Journal of Experimental Medicine. 208: 41-52. PMID 21187319 DOI: 10.1084/Jem.20101940  0.342
2011 Herzog M, Wendling O, Guillou F, Chambon P, Mark M, Losson R, Cammas F. TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis. Developmental Biology. 350: 548-58. PMID 21163256 DOI: 10.1016/J.Ydbio.2010.12.014  0.331
2011 Huang JK, Jarjour AA, Nait Oumesmar B, Kerninon C, Williams A, Krezel W, Kagechika H, Bauer J, Zhao C, Baron-Van Evercooren A, Chambon P, Ffrench-Constant C, Franklin RJ. Retinoid X receptor gamma signaling accelerates CNS remyelination. Nature Neuroscience. 14: 45-53. PMID 21131950 DOI: 10.1038/Nn.2702  0.672
2011 Tóth K, Sarang Z, Scholtz B, Brázda P, Ghyselinck N, Chambon P, Fésüs L, Szondy Z. Retinoids enhance glucocorticoid-induced apoptosis of T cells by facilitating glucocorticoid receptor-mediated transcription. Cell Death and Differentiation. 18: 783-92. PMID 21072052 DOI: 10.1038/Cdd.2010.136  0.398
2011 Liu C, Wang H, Chambon P, Liu F. Regulation of intermediate progenitor cells in developing cerebral cortex by Retinoic acid receptor alpha signaling Developmental Biology. 356: 183. DOI: 10.1016/J.Ydbio.2011.05.215  0.31
2010 He S, Pirity MK, Wang WL, Wolf L, Chauhan BK, Cveklova K, Tamm ER, Ashery-Padan R, Metzger D, Nakai A, Chambon P, Zavadil J, Cvekl A. Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation. Epigenetics & Chromatin. 3: 21. PMID 21118511 DOI: 10.1186/1756-8935-3-21  0.355
2010 Campbell L, Emmerson E, Davies F, Gilliver SC, Krust A, Chambon P, Ashcroft GS, Hardman MJ. Estrogen promotes cutaneous wound healing via estrogen receptor beta independent of its antiinflammatory activities. The Journal of Experimental Medicine. 207: 1825-33. PMID 20733032 DOI: 10.1084/Jem.20100500  0.314
2010 Sayama K, Kajiya K, Sugawara K, Sato S, Hirakawa S, Shirakata Y, Hanakawa Y, Dai X, Ishimatsu-Tsuji Y, Metzger D, Chambon P, Akira S, Paus R, Kishimoto J, Hashimoto K. Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice. Plos One. 5: e11275. PMID 20585657 DOI: 10.1371/Journal.Pone.0011275  0.337
2010 Hikake T, Hayashi S, Chambon P, Watanabe H, Iguchi T, Sato T. Differential involvement of insulin-like growth factor-I and estrogen on prolactin cells in the mouse anterior pituitary. Experimental Biology and Medicine (Maywood, N.J.). 235: 974-80. PMID 20576740 DOI: 10.1258/Ebm.2010.009396  0.309
2010 Morsut L, Yan KP, Enzo E, Aragona M, Soligo SM, Wendling O, Mark M, Khetchoumian K, Bressan G, Chambon P, Dupont S, Losson R, Piccolo S. Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo. Development (Cambridge, England). 137: 2571-8. PMID 20573697 DOI: 10.1242/Dev.053801  0.341
2010 Gilliver SC, Emmerson E, Campbell L, Chambon P, Hardman MJ, Ashcroft GS. 17beta-estradiol inhibits wound healing in male mice via estrogen receptor-alpha. The American Journal of Pathology. 176: 2707-21. PMID 20448060 DOI: 10.2353/Ajpath.2010.090432  0.304
2010 Rocher-Ros V, Marco S, Mao JH, Gines S, Metzger D, Chambon P, Balmain A, Saura CA. Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7. Oncogene. 29: 2950-61. PMID 20208556 DOI: 10.1038/Onc.2010.57  0.313
2010 Shimura E, Hozumi N, Kanagawa O, Metzger D, Chambon P, Radtke F, Hirose S, Nakano N. Epidermal gammadelta T cells sense precancerous cellular dysregulation and initiate immune responses. International Immunology. 22: 329-40. PMID 20185432 DOI: 10.1093/Intimm/Dxq014  0.312
2010 Joseph A, Hess RA, Schaeffer DJ, Ko C, Hudgin-Spivey S, Chambon P, Shur BD. Absence of estrogen receptor alpha leads to physiological alterations in the mouse epididymis and consequent defects in sperm function. Biology of Reproduction. 82: 948-57. PMID 20130267 DOI: 10.1095/Biolreprod.109.079889  0.317
2010 Joseph A, Shur BD, Ko C, Chambon P, Hess RA. Epididymal hypo-osmolality induces abnormal sperm morphology and function in the estrogen receptor alpha knockout mouse. Biology of Reproduction. 82: 958-67. PMID 20130266 DOI: 10.1095/Biolreprod.109.080366  0.313
2010 Li G, Margueron R, Ku M, Chambon P, Bernstein BE, Reinberg D. Jarid2 and PRC2, partners in regulating gene expression. Genes & Development. 24: 368-80. PMID 20123894 DOI: 10.1101/Gad.1886410  0.382
2010 Rosselot C, Spraggon L, Chia I, Batourina E, Riccio P, Lu B, Niederreither K, Dolle P, Duester G, Chambon P, Costantini F, Gilbert T, Molotkov A, Mendelsohn C. Non-cell-autonomous retinoid signaling is crucial for renal development. Development (Cambridge, England). 137: 283-92. PMID 20040494 DOI: 10.1242/Dev.040287  0.617
2010 Cheng L, Guo J, Sun L, Fu J, Barnes PF, Metzger D, Chambon P, Oshima RG, Amagai T, Su DM. Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy. The Journal of Biological Chemistry. 285: 5836-47. PMID 19955175 DOI: 10.1074/Jbc.M109.072124  0.35
2009 Chorro L, Sarde A, Li M, Woollard KJ, Chambon P, Malissen B, Kissenpfennig A, Barbaroux JB, Groves R, Geissmann F. Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network. The Journal of Experimental Medicine. 206: 3089-100. PMID 19995948 DOI: 10.1084/Jem.20091586  0.319
2009 Kirigaya A, Kim H, Hayashi S, Chambon P, Watanabe H, Lguchi T, Sato T. Involvement of estrogen receptor beta in the induction of polyovular follicles in mouse ovaries exposed neonatally to diethylstilbestrol. Zoological Science. 26: 704-12. PMID 19832683 DOI: 10.2108/Zsj.26.704  0.349
2009 Kim H, Nakajima T, Hayashi S, Chambon P, Watanabe H, Iguchi T, Sato T. Effects of diethylstilbestrol on programmed oocyte death and induction of polyovular follicles in neonatal mouse ovaries. Biology of Reproduction. 81: 1002-9. PMID 19553606 DOI: 10.1095/Biolreprod.108.070599  0.327
2009 Bourgo RJ, Siddiqui H, Fox S, Solomon D, Sansam CG, Yaniv M, Muchardt C, Metzger D, Chambon P, Roberts CW, Knudsen ES. SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity. Molecular Biology of the Cell. 20: 3192-9. PMID 19458193 DOI: 10.1091/Mbc.E08-12-1224  0.323
2009 Lee S, Kang DW, Hudgins-Spivey S, Krust A, Lee EY, Koo Y, Cheon Y, Gye MC, Chambon P, Ko C. Theca-specific estrogen receptor-alpha knockout mice lose fertility prematurely. Endocrinology. 150: 3855-62. PMID 19423761 DOI: 10.1210/En.2008-1774  0.377
2009 Mödder UI, Monroe DG, Fraser DG, Spelsberg TC, Rosen CJ, Géhin M, Chambon P, O'Malley BW, Khosla S. Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2. The Journal of Biological Chemistry. 284: 18767-77. PMID 19423703 DOI: 10.1074/Jbc.M109.000836  0.342
2009 Williams JA, Kondo N, Okabe T, Takeshita N, Pilchak DM, Koyama E, Ochiai T, Jensen D, Chu ML, Kane MA, Napoli JL, Enomoto-Iwamoto M, Ghyselinck N, Chambon P, Pacifici M, et al. Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse. Developmental Biology. 328: 315-27. PMID 19389355 DOI: 10.1016/J.Ydbio.2009.01.031  0.372
2009 Mark M, Ghyselinck NB, Chambon P. Function of retinoic acid receptors during embryonic development. Nuclear Receptor Signaling. 7: e002. PMID 19381305 DOI: 10.1621/Nrs.07002  0.38
2009 Zhao Z, Park C, McDevitt MA, Glidewell-Kenney C, Chambon P, Weiss J, Jameson JL, Levine JE. p21-Activated kinase mediates rapid estradiol-negative feedback actions in the reproductive axis. Proceedings of the National Academy of Sciences of the United States of America. 106: 7221-6. PMID 19359483 DOI: 10.1073/Pnas.0812597106  0.331
2009 Mascrez B, Ghyselinck NB, Chambon P, Mark M. A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development. Proceedings of the National Academy of Sciences of the United States of America. 106: 4272-7. PMID 19255444 DOI: 10.1073/Pnas.0813143106  0.373
2009 Billon-Galés A, Fontaine C, Filipe C, Douin-Echinard V, Fouque MJ, Flouriot G, Gourdy P, Lenfant F, Laurell H, Krust A, Chambon P, Arnal JF. The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol. Proceedings of the National Academy of Sciences of the United States of America. 106: 2053-8. PMID 19188600 DOI: 10.1073/Pnas.0808742106  0.349
2009 Golonzhka O, Liang X, Messaddeq N, Bornert JM, Campbell AL, Metzger D, Chambon P, Ganguli-Indra G, Leid M, Indra AK. Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation. The Journal of Investigative Dermatology. 129: 1459-70. PMID 19092943 DOI: 10.1038/Jid.2008.392  0.345
2008 Mandillo S, Tucci V, Hölter SM, Meziane H, Banchaabouchi MA, Kallnik M, Lad HV, Nolan PM, Ouagazzal AM, Coghill EL, Gale K, Golini E, Jacquot S, Krezel W, Parker A, ... ... Chambon P, et al. Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. Physiological Genomics. 34: 243-55. PMID 18505770 DOI: 10.1152/Physiolgenomics.90207.2008  0.599
2008 Küppers E, Krust A, Chambon P, Beyer C. Functional alterations of the nigrostriatal dopamine system in estrogen receptor-alpha knockout (ERKO) mice. Psychoneuroendocrinology. 33: 832-8. PMID 18472350 DOI: 10.1016/J.Psyneuen.2008.03.007  0.36
2008 Liao WL, Tsai HC, Wang HF, Chang J, Lu KM, Wu HL, Lee YC, Tsai TF, Takahashi H, Wagner M, Ghyselinck NB, Chambon P, Liu FC. Modular patterning of structure and function of the striatum by retinoid receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 6765-70. PMID 18443282 DOI: 10.1073/Pnas.0802109105  0.358
2008 Douin-Echinard V, Laffont S, Seillet C, Delpy L, Krust A, Chambon P, Gourdy P, Arnal JF, Guéry JC. Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and [corrected] CD40-induced cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 180: 3661-9. PMID 18322171 DOI: 10.4049/Jimmunol.180.6.3661  0.318
2008 Ignat M, Teletin M, Tisserand J, Khetchoumian K, Dennefeld C, Chambon P, Losson R, Mark M. Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1alpha. Proceedings of the National Academy of Sciences of the United States of America. 105: 2598-603. PMID 18287084 DOI: 10.1073/Pnas.0712030105  0.378
2008 Antal MC, Krust A, Chambon P, Mark M. Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant. Proceedings of the National Academy of Sciences of the United States of America. 105: 2433-8. PMID 18268329 DOI: 10.1073/Pnas.0712029105  0.347
2008 Claxton S, Kostourou V, Jadeja S, Chambon P, Hodivala-Dilke K, Fruttiger M. Efficient, inducible Cre-recombinase activation in vascular endothelium. Genesis (New York, N.Y. : 2000). 46: 74-80. PMID 18257043 DOI: 10.1002/Dvg.20367  0.316
2008 Gieske MC, Kim HJ, Legan SJ, Koo Y, Krust A, Chambon P, Ko C. Pituitary gonadotroph estrogen receptor-alpha is necessary for fertility in females. Endocrinology. 149: 20-7. PMID 17947360 DOI: 10.1210/En.2007-1084  0.342
2008 Douin-Echinard V, Laffont S, Seillet C, Delpy L, Krust A, Chambon P, Gourdy P, Arnal J, Guery J. Estrogen Receptor α, but Not β, Is Required for Optimal Dendritic Cell Differentiation and of CD40-Induced Cytokine Production Journal of Immunology. 180: 7047-7047. DOI: 10.4049/Jimmunol.180.10.7047-B  0.311
2007 Ruiz A, Ghyselinck NB, Mata N, Nusinowitz S, Lloyd M, Dennefeld C, Chambon P, Bok D. Somatic ablation of the Lrat gene in the mouse retinal pigment epithelium drastically reduces its retinoid storage. Investigative Ophthalmology & Visual Science. 48: 5377-87. PMID 18055784 DOI: 10.1167/Iovs.07-0673  0.301
2007 Khetchoumian K, Teletin M, Tisserand J, Mark M, Herquel B, Ignat M, Zucman-Rossi J, Cammas F, Lerouge T, Thibault C, Metzger D, Chambon P, Losson R. Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha. Nature Genetics. 39: 1500-6. PMID 18026104 DOI: 10.1038/Ng.2007.15  0.372
2007 Kim HJ, Gieske MC, Hudgins S, Kim BG, Krust A, Chambon P, Ko C. Estrogen receptor alpha-induced cholecystokinin type A receptor expression in the female mouse pituitary. The Journal of Endocrinology. 195: 393-405. PMID 18000302 DOI: 10.1677/Joe-07-0358  0.364
2007 Slezak M, Göritz C, Niemiec A, Frisén J, Chambon P, Metzger D, Pfrieger FW. Transgenic mice for conditional gene manipulation in astroglial cells. Glia. 55: 1565-76. PMID 17823970 DOI: 10.1002/Glia.20570  0.332
2007 McDevitt MA, Glidewell-Kenney C, Weiss J, Chambon P, Jameson JL, Levine JE. Estrogen response element-independent estrogen receptor (ER)-alpha signaling does not rescue sexual behavior but restores normal testosterone secretion in male ERalpha knockout mice. Endocrinology. 148: 5288-94. PMID 17673514 DOI: 10.1210/En.2007-0673  0.344
2007 Cederroth CR, Schaad O, Descombes P, Chambon P, Vassalli JD, Nef S. Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism. Endocrinology. 148: 5507-19. PMID 17673513 DOI: 10.1210/En.2007-0689  0.391
2007 MacLean G, Li H, Metzger D, Chambon P, Petkovich M. Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. Endocrinology. 148: 4560-7. PMID 17584971 DOI: 10.1210/En.2007-0492  0.337
2007 Walkley CR, Olsen GH, Dworkin S, Fabb SA, Swann J, McArthur GA, Westmoreland SV, Chambon P, Scadden DT, Purton LE. A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell. 129: 1097-110. PMID 17574023 DOI: 10.1016/J.Cell.2007.05.014  0.328
2007 Dali-Youcef N, Mataki C, Coste A, Messaddeq N, Giroud S, Blanc S, Koehl C, Champy MF, Chambon P, Fajas L, Metzger D, Schoonjans K, Auwerx J. Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure. Proceedings of the National Academy of Sciences of the United States of America. 104: 10703-8. PMID 17556545 DOI: 10.1073/Pnas.0611568104  0.301
2007 Indra AK, Castaneda E, Antal MC, Jiang M, Messaddeq N, Meng X, Loehr CV, Gariglio P, Kato S, Wahli W, Desvergne B, Metzger D, Chambon P. Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes. The Journal of Investigative Dermatology. 127: 1250-60. PMID 17301838 DOI: 10.1038/Sj.Jid.5700672  0.362
2007 Dzhagalov I, Chambon P, He YW. Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma. Journal of Immunology (Baltimore, Md. : 1950). 178: 2113-21. PMID 17277115 DOI: 10.4049/Jimmunol.178.4.2113  0.327
2007 Syed FA, Fraser DG, Spelsberg TC, Rosen CJ, Krust A, Chambon P, Jameson JL, Khosla S. Effects of loss of classical estrogen response element signaling on bone in male mice. Endocrinology. 148: 1902-10. PMID 17204553 DOI: 10.1210/En.2006-1165  0.309
2007 Patchev AV, Fischer D, Wolf SS, Herkenham M, Götz F, Gehin M, Chambon P, Patchev VK, Almeida OF. Insidious adrenocortical insufficiency underlies neuroendocrine dysregulation in TIF-2 deficient mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 231-8. PMID 17135362 DOI: 10.1096/Fj.06-6952Com  0.366
2007 Uehara M, Yashiro K, Mamiya S, Nishino J, Chambon P, Dolle P, Sakai Y. CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse. Developmental Biology. 302: 399-411. PMID 17067568 DOI: 10.1016/J.Ydbio.2006.09.045  0.608
2006 Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LXIII. Retinoid X receptors. Pharmacological Reviews. 58: 760-72. PMID 17132853 DOI: 10.1124/Pr.58.4.7  0.364
2006 Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LX. Retinoic acid receptors. Pharmacological Reviews. 58: 712-25. PMID 17132850 DOI: 10.1124/Pr.58.4.4  0.356
2006 Vernet N, Dennefeld C, Guillou F, Chambon P, Ghyselinck NB, Mark M. Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells. The Embo Journal. 25: 5816-25. PMID 17124491 DOI: 10.1038/Sj.Emboj.7601447  0.411
2006 Mukherjee A, Soyal SM, Fernandez-Valdivia R, Gehin M, Chambon P, Demayo FJ, Lydon JP, O'Malley BW. Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Molecular and Cellular Biology. 26: 6571-83. PMID 16914740 DOI: 10.1128/Mcb.00654-06  0.387
2006 Li M, Hener P, Zhang Z, Kato S, Metzger D, Chambon P. Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis. Proceedings of the National Academy of Sciences of the United States of America. 103: 11736-41. PMID 16880407 DOI: 10.1073/Pnas.0604575103  0.349
2006 Calléja C, Messaddeq N, Chapellier B, Yang H, Krezel W, Li M, Metzger D, Mascrez B, Ohta K, Kagechika H, Endo Y, Mark M, Ghyselinck NB, Chambon P. Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes. Genes & Development. 20: 1525-38. PMID 16751185 DOI: 10.1101/Gad.368706  0.68
2006 Qiu J, Bosch MA, Tobias SC, Krust A, Graham SM, Murphy SJ, Korach KS, Chambon P, Scanlan TS, Rønnekleiv OK, Kelly MJ. A G-protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5649-55. PMID 16723521 DOI: 10.1523/Jneurosci.0327-06.2006  0.322
2006 Purton LE, Dworkin S, Olsen GH, Walkley CR, Fabb SA, Collins SJ, Chambon P. RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation. The Journal of Experimental Medicine. 203: 1283-93. PMID 16682494 DOI: 10.1084/Jem.20052105  0.338
2006 Imayoshi I, Ohtsuka T, Metzger D, Chambon P, Kageyama R. Temporal regulation of Cre recombinase activity in neural stem cells. Genesis (New York, N.Y. : 2000). 44: 233-8. PMID 16652364 DOI: 10.1002/Dvg.20212  0.317
2006 Ghyselinck NB, Vernet N, Dennefeld C, Giese N, Nau H, Chambon P, Viville S, Mark M. Retinoids and spermatogenesis: lessons from mutant mice lacking the plasma retinol binding protein. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 1608-22. PMID 16586441 DOI: 10.1002/Dvdy.20795  0.359
2006 Vermot J, Garnier JM, Dierich A, Niederreither K, Harvey RP, Chambon P, Dollé P. Conditional (loxP-flanked) allele for the gene encoding the retinoic acid-synthesizing enzyme retinaldehyde dehydrogenase 2 (RALDH2). Genesis (New York, N.Y. : 2000). 44: 155-8. PMID 16496350 DOI: 10.1002/Gene.20195  0.359
2006 Watanabe H, Takahashi E, Kobayashi M, Goto M, Krust A, Chambon P, Iguchi T. The estrogen-responsive adrenomedullin and receptor-modifying protein 3 gene identified by DNA microarray analysis are directly regulated by estrogen receptor. Journal of Molecular Endocrinology. 36: 81-9. PMID 16461929 DOI: 10.1677/Jme.1.01825  0.406
2006 Mallepell S, Krust A, Chambon P, Brisken C. Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland. Proceedings of the National Academy of Sciences of the United States of America. 103: 2196-201. PMID 16452162 DOI: 10.1073/Pnas.0510974103  0.374
2006 Desai TJ, Chen F, Lü J, Qian J, Niederreither K, Dollé P, Chambon P, Cardoso WV. Distinct roles for retinoic acid receptors alpha and beta in early lung morphogenesis. Developmental Biology. 291: 12-24. PMID 16427040 DOI: 10.1016/J.Ydbio.2005.10.045  0.312
2006 Mark M, Ghyselinck NB, Chambon P. Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis. Annual Review of Pharmacology and Toxicology. 46: 451-80. PMID 16402912 DOI: 10.1146/Annurev.Pharmtox.46.120604.141156  0.356
2006 Stratis A, Pasparakis M, Markur D, Knaup R, Pofahl R, Metzger D, Chambon P, Krieg T, Haase I. Localized inflammatory skin disease following inducible ablation of I kappa B kinase 2 in murine epidermis. The Journal of Investigative Dermatology. 126: 614-20. PMID 16397523 DOI: 10.1038/Sj.Jid.5700092  0.3
2006 Shiina H, Matsumoto T, Sato T, Igarashi K, Miyamoto J, Takemasa S, Sakari M, Takada I, Nakamura T, Metzger D, Chambon P, Kanno J, Yoshikawa H, Kato S. Premature ovarian failure in androgen receptor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 224-9. PMID 16373508 DOI: 10.1073/Pnas.0506736102  0.355
2006 Matsumoto S, Banine F, Struve J, Xing R, Adams C, Liu Y, Metzger D, Chambon P, Rao MS, Sherman LS. Brg1 is required for murine neural stem cell maintenance and gliogenesis. Developmental Biology. 289: 372-83. PMID 16330018 DOI: 10.1016/J.Ydbio.2005.10.044  0.326
2006 Sharma V, Hays WR, Wood WM, Pugazhenthi U, St Germain DL, Bianco AC, Krezel W, Chambon P, Haugen BR. Effects of rexinoids on thyrotrope function and the hypothalamic-pituitary-thyroid axis. Endocrinology. 147: 1438-51. PMID 16306084 DOI: 10.1210/En.2005-0706  0.679
2006 Vernet N, Dennefeld C, Rochette-Egly C, Oulad-Abdelghani M, Chambon P, Ghyselinck NB, Mark M. Retinoic acid metabolism and signaling pathways in the adult and developing mouse testis. Endocrinology. 147: 96-110. PMID 16210368 DOI: 10.1210/En.2005-0953  0.335
2006 Li XG, Okada T, Kodera M, Nara Y, Takino N, Muramatsu C, Ikeguchi K, Urano F, Ichinose H, Metzger D, Chambon P, Nakano I, Ozawa K, Muramatsu S. Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 160-6. PMID 16182609 DOI: 10.1016/J.Ymthe.2005.08.009  0.344
2005 Herrmann T, Gröne HJ, Langbein L, Kaiser I, Gosch I, Bennemann U, Metzger D, Chambon P, Stewart AF, Stremmel W. Disturbed epidermal structure in mice with temporally controlled fatp4 deficiency. The Journal of Investigative Dermatology. 125: 1228-35. PMID 16354193 DOI: 10.1111/J.0022-202X.2005.23972.X  0.342
2005 Lucey MJ, Chen D, Lopez-Garcia J, Hart SM, Phoenix F, Al-Jehani R, Alao JP, White R, Kindle KB, Losson R, Chambon P, Parker MG, Schär P, Heery DM, Buluwela L, et al. T:G mismatch-specific thymine-DNA glycosylase (TDG) as a coregulator of transcription interacts with SRC1 family members through a novel tyrosine repeat motif. Nucleic Acids Research. 33: 6393-404. PMID 16282588 DOI: 10.1093/Nar/Gki940  0.325
2005 Syed FA, Mödder UI, Fraser DG, Spelsberg TC, Rosen CJ, Krust A, Chambon P, Jameson JL, Khosla S. Skeletal effects of estrogen are mediated by opposing actions of classical and nonclassical estrogen receptor pathways. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1992-2001. PMID 16234973 DOI: 10.1359/Jbmr.050713  0.317
2005 Matt N, Dupé V, Garnier JM, Dennefeld C, Chambon P, Mark M, Ghyselinck NB. Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells. Development (Cambridge, England). 132: 4789-800. PMID 16207763 DOI: 10.1242/Dev.02031  0.305
2005 Li M, Messaddeq N, Teletin M, Pasquali JL, Metzger D, Chambon P. Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin. Proceedings of the National Academy of Sciences of the United States of America. 102: 14795-800. PMID 16199515 DOI: 10.1073/Pnas.0507385102  0.319
2005 Indra AK, Dupé V, Bornert JM, Messaddeq N, Yaniv M, Mark M, Chambon P, Metzger D. Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation. Development (Cambridge, England). 132: 4533-44. PMID 16192310 DOI: 10.1242/Dev.02019  0.41
2005 Hoegberg P, Schmidt CK, Fletcher N, Nilsson CB, Trossvik C, Gerlienke Schuur A, Brouwer A, Nau H, Ghyselinck NB, Chambon P, HÃ¥kansson H. Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms. Chemico-Biological Interactions. 156: 25-39. PMID 16109390 DOI: 10.1016/J.Cbi.2005.06.006  0.336
2005 Martín M, Gallego-Llamas J, Ribes V, Kedinger M, Niederreither K, Chambon P, Dollé P, Gradwohl G. Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Developmental Biology. 284: 399-411. PMID 16026781 DOI: 10.1016/J.Ydbio.2005.05.035  0.372
2005 Wietrzych M, Meziane H, Sutter A, Ghyselinck N, Chapman PF, Chambon P, Krezel W. Working memory deficits in retinoid X receptor gamma-deficient mice. Learning & Memory (Cold Spring Harbor, N.Y.). 12: 318-26. PMID 15897255 DOI: 10.1101/Lm.89805  0.66
2005 Schnütgen F, De-Zolt S, Van Sloun P, Hollatz M, Floss T, Hansen J, Altschmied J, Seisenberger C, Ghyselinck NB, Ruiz P, Chambon P, Wurst W, von Melchner H. Genomewide production of multipurpose alleles for the functional analysis of the mouse genome. Proceedings of the National Academy of Sciences of the United States of America. 102: 7221-6. PMID 15870191 DOI: 10.1073/Pnas.0502273102  0.332
2005 Pavri R, Lewis B, Kim TK, Dilworth FJ, Erdjument-Bromage H, Tempst P, de Murcia G, Evans R, Chambon P, Reinberg D. PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Molecular Cell. 18: 83-96. PMID 15808511 DOI: 10.1016/J.Molcel.2005.02.034  0.392
2005 Matt N, Schmidt CK, Dupé V, Dennefeld C, Nau H, Chambon P, Mark M, Ghyselinck NB. Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 167-76. PMID 15765518 DOI: 10.1002/Dvdy.20313  0.35
2005 Vermot J, Schuhbaur B, Le Mouellic H, McCaffery P, Garnier JM, Hentsch D, Brûlet P, Niederreither K, Chambon P, Dollé P, Le Roux I. Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons. Development (Cambridge, England). 132: 1611-21. PMID 15753214 DOI: 10.1242/Dev.01718  0.331
2005 Liao WL, Wang HF, Tsai HC, Chambon P, Wagner M, Kakizuka A, Liu FC. Retinoid signaling competence and RARbeta-mediated gene regulation in the developing mammalian telencephalon. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 887-900. PMID 15736225 DOI: 10.1002/Dvdy.20281  0.395
2005 Serpente P, Tümpel S, Ghyselinck NB, Niederreither K, Wiedemann LM, Dollé P, Chambon P, Krumlauf R, Gould AP. Direct crossregulation between retinoic acid receptor {beta} and Hox genes during hindbrain segmentation. Development (Cambridge, England). 132: 503-13. PMID 15634700 DOI: 10.1242/Dev.01593  0.38
2005 Metzger D, Li M, Chambon P. Targeted somatic mutagenesis in the mouse epidermis. Methods in Molecular Biology (Clifton, N.J.). 289: 329-40. PMID 15502196 DOI: 10.1385/1-59259-830-7:329  0.366
2004 Mark M, Ghyselinck NB, Chambon P. Retinoic acid signalling in the development of branchial arches. Current Opinion in Genetics & Development. 14: 591-8. PMID 15380252 DOI: 10.1016/J.Gde.2004.07.012  0.302
2004 Cammas F, Herzog M, Lerouge T, Chambon P, Losson R. Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation. Genes & Development. 18: 2147-60. PMID 15342492 DOI: 10.1101/Gad.302904  0.37
2004 Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, et al. The European dimension for the mouse genome mutagenesis program. Nature Genetics. 36: 925-7. PMID 15340424 DOI: 10.1038/Ng0904-925  0.468
2004 Khetchoumian K, Teletin M, Mark M, Lerouge T, Cerviño M, Oulad-Abdelghani M, Chambon P, Losson R. TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids. The Journal of Biological Chemistry. 279: 48329-41. PMID 15322135 DOI: 10.1074/Jbc.M404779200  0.368
2004 Garidou L, Laffont S, Douin-Echinard V, Coureau C, Krust A, Chambon P, Guéry JC. Estrogen receptor alpha signaling in inflammatory leukocytes is dispensable for 17beta-estradiol-mediated inhibition of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 2435-42. PMID 15294957 DOI: 10.4049/Jimmunol.173.4.2435  0.33
2004 el Marjou F, Janssen KP, Chang BH, Li M, Hindie V, Chan L, Louvard D, Chambon P, Metzger D, Robine S. Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis (New York, N.Y. : 2000). 39: 186-93. PMID 15282745 DOI: 10.1002/Gene.20042  0.373
2004 Schuler M, Dierich A, Chambon P, Metzger D. Efficient temporally controlled targeted somatic mutagenesis in hepatocytes of the mouse. Genesis (New York, N.Y. : 2000). 39: 167-72. PMID 15282742 DOI: 10.1002/Gene.20039  0.365
2004 Yan KP, Dollé P, Mark M, Lerouge T, Wendling O, Chambon P, Losson R. Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1 gamma gene. Gene. 334: 3-13. PMID 15256250 DOI: 10.1016/J.Gene.2004.02.056  0.39
2004 Rieusset J, Seydoux J, Anghel SI, Escher P, Michalik L, Soon Tan N, Metzger D, Chambon P, Wahli W, Desvergne B. Altered growth in male peroxisome proliferator-activated receptor gamma (PPARgamma) heterozygous mice: involvement of PPARgamma in a negative feedback regulation of growth hormone action. Molecular Endocrinology (Baltimore, Md.). 18: 2363-77. PMID 15231871 DOI: 10.1210/Me.2003-0325  0.362
2004 Molotkov A, Ghyselinck NB, Chambon P, Duester G. Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation. The Biochemical Journal. 383: 295-302. PMID 15193143 DOI: 10.1042/Bj20040621  0.325
2004 Okada A, Ohta Y, Brody SL, Watanabe H, Krust A, Chambon P, Iguchi T. Role of foxj1 and estrogen receptor alpha in ciliated epithelial cell differentiation of the neonatal oviduct. Journal of Molecular Endocrinology. 32: 615-25. PMID 15171704 DOI: 10.1677/Jme.0.0320615  0.369
2004 Nielsen AL, Jørgensen P, Lerouge T, Cerviño M, Chambon P, Losson R. Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif. Molecular and Cellular Biology. 24: 5184-96. PMID 15169884 DOI: 10.1128/Mcb.24.12.5184-5196.2004  0.33
2004 Jia Y, Qi C, Kashireddi P, Surapureddi S, Zhu YJ, Rao MS, Le Roith D, Chambon P, Gonzalez FJ, Reddy JK. Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver. The Journal of Biological Chemistry. 279: 24427-34. PMID 15150259 DOI: 10.1074/Jbc.M402391200  0.397
2004 IJpenberg A, Tan NS, Gelman L, Kersten S, Seydoux J, Xu J, Metzger D, Canaple L, Chambon P, Wahli W, Desvergne B. In vivo activation of PPAR target genes by RXR homodimers. The Embo Journal. 23: 2083-91. PMID 15103326 DOI: 10.1038/Sj.Emboj.7600209  0.392
2004 Andl T, Ahn K, Kairo A, Chu EY, Wine-Lee L, Reddy ST, Croft NJ, Cebra-Thomas JA, Metzger D, Chambon P, Lyons KM, Mishina Y, Seykora JT, Crenshaw EB, Millar SE. Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (Cambridge, England). 131: 2257-68. PMID 15102710 DOI: 10.1242/Dev.01125  0.368
2004 Schmuth M, Haqq CM, Cairns WJ, Holder JC, Dorsam S, Chang S, Lau P, Fowler AJ, Chuang G, Moser AH, Brown BE, Mao-Qiang M, Uchida Y, Schoonjans K, Auwerx J, ... Chambon P, et al. Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes. The Journal of Investigative Dermatology. 122: 971-83. PMID 15102088 DOI: 10.1111/J.0022-202X.2004.22412.X  0.348
2004 Haugen BR, Jensen DR, Sharma V, Pulawa LK, Hays WR, Krezel W, Chambon P, Eckel RH. Retinoid X receptor gamma-deficient mice have increased skeletal muscle lipoprotein lipase activity and less weight gain when fed a high-fat diet. Endocrinology. 145: 3679-85. PMID 15087432 DOI: 10.1210/En.2003-1401  0.658
2004 Imai T, Takakuwa R, Marchand S, Dentz E, Bornert JM, Messaddeq N, Wendling O, Mark M, Desvergne B, Wahli W, Chambon P, Metzger D. Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 101: 4543-7. PMID 15070754 DOI: 10.1073/Pnas.0400356101  0.343
2004 Mark M, Yoshida-Komiya H, Gehin M, Liao L, Tsai MJ, O'Malley BW, Chambon P, Xu J. Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proceedings of the National Academy of Sciences of the United States of America. 101: 4453-8. PMID 15070739 DOI: 10.1073/Pnas.0400234101  0.332
2004 Mascrez B, Ghyselinck NB, Watanabe M, Annicotte JS, Chambon P, Auwerx J, Mark M. Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells. Embo Reports. 5: 285-90. PMID 14993927 DOI: 10.1038/Sj.Embor.7400094  0.362
2004 Mori M, Metzger D, Picaud S, Hindelang C, Simonutti M, Sahel J, Chambon P, Mark M. Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epithelium. The American Journal of Pathology. 164: 701-10. PMID 14742273 DOI: 10.1016/S0002-9440(10)63157-4  0.307
2004 Walkley CR, Purton LE, Snelling HJ, Yuan YD, Nakajima H, Chambon P, Chandraratna RA, McArthur GA. Identification of the molecular requirements for an RAR alpha-mediated cell cycle arrest during granulocytic differentiation. Blood. 103: 1286-95. PMID 14576045 DOI: 10.1182/Blood-2003-07-2391  0.37
2004 H??lter S, Auwerx J, Brown S, Chambon P, Coghill E, Gale K, Golini E, Jacquot S, Krezel W, Lad H, Mandillo S, Marazziti D, Meziane H, Nolan P, Ouagazzal A, et al. P30 EUROPEAN COMPREHENSIVE FIRST-LINE PHENOTYPING PROTOCOL FOR MICE: CROSS-LABORATORY VALIDATION OF A PRIMARY BEHAVIOURAL SCREEN TEST BATTERY Behavioural Pharmacology. 15: A17. DOI: 10.1097/00008877-200409000-00070  0.602
2003 Metzger D, Indra AK, Li M, Chapellier B, Calleja C, Ghyselinck NB, Chambon P. Targeted conditional somatic mutagenesis in the mouse: temporally-controlled knock out of retinoid receptors in epidermal keratinocytes. Methods in Enzymology. 364: 379-408. PMID 14631857 DOI: 10.1016/S0076-6879(03)64022-X  0.37
2003 Dupé V, Matt N, Garnier JM, Chambon P, Mark M, Ghyselinck NB. A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment. Proceedings of the National Academy of Sciences of the United States of America. 100: 14036-41. PMID 14623956 DOI: 10.1073/Pnas.2336223100  0.33
2003 Chi TH, Wan M, Lee PP, Akashi K, Metzger D, Chambon P, Wilson CB, Crabtree GR. Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity. 19: 169-82. PMID 12932351 DOI: 10.1016/S1074-7613(03)00199-7  0.329
2003 Geissmann F, Revy P, Brousse N, Lepelletier Y, Folli C, Durandy A, Chambon P, Dy M. Retinoids regulate survival and antigen presentation by immature dendritic cells. The Journal of Experimental Medicine. 198: 623-34. PMID 12925678 DOI: 10.1084/Jem.20030390  0.334
2003 Vegeto E, Belcredito S, Etteri S, Ghisletti S, Brusadelli A, Meda C, Krust A, Dupont S, Ciana P, Chambon P, Maggi A. Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol. Proceedings of the National Academy of Sciences of the United States of America. 100: 9614-9. PMID 12878732 DOI: 10.1073/Pnas.1531957100  0.303
2003 Kawano H, Sato T, Yamada T, Matsumoto T, Sekine K, Watanabe T, Nakamura T, Fukuda T, Yoshimura K, Yoshizawa T, Aihara K, Yamamoto Y, Nakamichi Y, Metzger D, Chambon P, et al. Suppressive function of androgen receptor in bone resorption. Proceedings of the National Academy of Sciences of the United States of America. 100: 9416-21. PMID 12872002 DOI: 10.1073/Pnas.1533500100  0.314
2003 Rayasam GV, Wendling O, Angrand PO, Mark M, Niederreither K, Song L, Lerouge T, Hager GL, Chambon P, Losson R. NSD1 is essential for early post-implantation development and has a catalytically active SET domain. The Embo Journal. 22: 3153-63. PMID 12805229 DOI: 10.1093/Emboj/Cdg288  0.318
2003 Ohtake F, Takeyama K, Matsumoto T, Kitagawa H, Yamamoto Y, Nohara K, Tohyama C, Krust A, Mimura J, Chambon P, Yanagisawa J, Fujii-Kuriyama Y, Kato S. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature. 423: 545-50. PMID 12774124 DOI: 10.1038/Nature01606  0.361
2003 Ménissier de Murcia J, Ricoul M, Tartier L, Niedergang C, Huber A, Dantzer F, Schreiber V, Amé JC, Dierich A, LeMeur M, Sabatier L, Chambon P, de Murcia G. Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse. The Embo Journal. 22: 2255-63. PMID 12727891 DOI: 10.1093/Emboj/Cdg206  0.329
2003 Leone DP, Genoud S, Atanasoski S, Grausenburger R, Berger P, Metzger D, Macklin WB, Chambon P, Suter U. Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells. Molecular and Cellular Neurosciences. 22: 430-40. PMID 12727441 DOI: 10.1016/S1044-7431(03)00029-0  0.375
2003 Niederreither K, Vermot J, Le Roux I, Schuhbaur B, Chambon P, Dollé P. The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system. Development (Cambridge, England). 130: 2525-34. PMID 12702665 DOI: 10.1242/Dev.00463  0.344
2003 Matt N, Ghyselinck NB, Wendling O, Chambon P, Mark M. Retinoic acid-induced developmental defects are mediated by RARbeta/RXR heterodimers in the pharyngeal endoderm. Development (Cambridge, England). 130: 2083-93. PMID 12668623 DOI: 10.1242/Dev.00428  0.372
2003 Schnütgen F, Doerflinger N, Calléja C, Wendling O, Chambon P, Ghyselinck NB. A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse. Nature Biotechnology. 21: 562-5. PMID 12665802 DOI: 10.1038/Nbt811  0.386
2003 Maret A, Coudert JD, Garidou L, Foucras G, Gourdy P, Krust A, Dupont S, Chambon P, Druet P, Bayard F, Guéry JC. Estradiol enhances primary antigen-specific CD4 T cell responses and Th1 development in vivo. Essential role of estrogen receptor alpha expression in hematopoietic cells. European Journal of Immunology. 33: 512-21. PMID 12645950 DOI: 10.1002/Immu.200310027  0.331
2003 Abu-Abed S, Dollé P, Metzger D, Wood C, MacLean G, Chambon P, Petkovich M. Developing with lethal RA levels: genetic ablation of Rarg can restore the viability of mice lacking Cyp26a1. Development (Cambridge, England). 130: 1449-59. PMID 12588859 DOI: 10.1242/Dev.00357  0.329
2003 Vermot J, Niederreither K, Garnier JM, Chambon P, Dollé P. Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 1763-8. PMID 12563036 DOI: 10.1073/Pnas.0437920100  0.337
2003 Wen F, Cecena G, Munoz-Ritchie V, Fuchs E, Chambon P, Oshima RG. Expression of conditional cre recombinase in epithelial tissues of transgenic mice. Genesis (New York, N.Y. : 2000). 35: 100-6. PMID 12533792 DOI: 10.1002/Gene.10169  0.378
2003 Weber P, Schuler M, Gérard C, Mark M, Metzger D, Chambon P. Temporally controlled site-specific mutagenesis in the germ cell lineage of the mouse testis. Biology of Reproduction. 68: 553-9. PMID 12533419 DOI: 10.1095/Biolreprod.102.005801  0.343
2003 Oosterveen T, Niederreither K, Dollé P, Chambon P, Meijlink F, Deschamps J. Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain. The Embo Journal. 22: 262-9. PMID 12514132 DOI: 10.1093/Emboj/Cdg029  0.364
2003 Dupont S, Dennefeld C, Krust A, Chambon P, Mark M. Expression of Sox9 in granulosa cells lacking the estrogen receptors, ERalpha and ERbeta. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 226: 103-6. PMID 12508230 DOI: 10.1002/Dvdy.10202  0.355
2003 Mark M, Chambon P. Functions of RARs and RXRs in vivo: Genetic dissection of the retinoid signaling pathway Pure and Applied Chemistry. 75: 1709-1732. DOI: 10.1351/Pac200375111709  0.388
2002 Romand R, Hashino E, Dollé P, Vonesch JL, Chambon P, Ghyselinck NB. The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Mechanisms of Development. 119: 213-23. PMID 12464434 DOI: 10.1016/S0925-4773(02)00385-4  0.41
2002 Niederreither K, Vermot J, Fraulob V, Chambon P, Dolle P. Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo. Proceedings of the National Academy of Sciences of the United States of America. 99: 16111-6. PMID 12454286 DOI: 10.1073/Pnas.252626599  0.596
2002 Nielsen AL, Sanchez C, Ichinose H, Cerviño M, Lerouge T, Chambon P, Losson R. Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha. The Embo Journal. 21: 5797-806. PMID 12411497 DOI: 10.1093/Emboj/Cdf560  0.33
2002 Gehin M, Mark M, Dennefeld C, Dierich A, Gronemeyer H, Chambon P. The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP. Molecular and Cellular Biology. 22: 5923-37. PMID 12138202 DOI: 10.1128/Mcb.22.16.5923-5937.2002  0.357
2002 Giannì M, Bauer A, Garattini E, Chambon P, Rochette-Egly C. Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RAR gamma degradation and transactivation. The Embo Journal. 21: 3760-9. PMID 12110588 DOI: 10.1093/Emboj/Cdf374  0.323
2002 Chapellier B, Mark M, Messaddeq N, Calléja C, Warot X, Brocard J, Gérard C, Li M, Metzger D, Ghyselinck NB, Chambon P. Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled. The Embo Journal. 21: 3402-13. PMID 12093741 DOI: 10.1093/Emboj/Cdf331  0.34
2002 Pare G, Krust A, Karas RH, Dupont S, Aronovitz M, Chambon P, Mendelsohn ME. Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury. Circulation Research. 90: 1087-92. PMID 12039798 DOI: 10.1161/01.Res.0000021114.92282.Fa  0.321
2002 Benecke A, Gaudon C, Garnier JM, vom Baur E, Chambon P, Losson R. ADA3-containing complexes associate with estrogen receptor alpha. Nucleic Acids Research. 30: 2508-14. PMID 12034840 DOI: 10.1093/Nar/30.11.2508  0.376
2002 Bastien J, Adam-Stitah S, Plassat JL, Chambon P, Rochette-Egly C. The phosphorylation site located in the A region of retinoic X receptor alpha is required for the antiproliferative effect of retinoic acid (RA) and the activation of RA target genes in F9 cells. The Journal of Biological Chemistry. 277: 28683-9. PMID 12032153 DOI: 10.1074/Jbc.M203623200  0.349
2002 Gianni M, Kopf E, Bastien J, Oulad-Abdelghani M, Garattini E, Chambon P, Rochette-Egly C. Down-regulation of the phosphatidylinositol 3-kinase/Akt pathway is involved in retinoic acid-induced phosphorylation, degradation, and transcriptional activity of retinoic acid receptor gamma 2. The Journal of Biological Chemistry. 277: 24859-62. PMID 12032135 DOI: 10.1074/Jbc.C200230200  0.311
2002 Niederreither K, Abu-Abed S, Schuhbaur B, Petkovich M, Chambon P, Dollé P. Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development. Nature Genetics. 31: 84-8. PMID 11953746 DOI: 10.1038/Ng876  0.351
2002 Weiss RE, Gehin M, Xu J, Sadow PM, O'Malley BW, Chambon P, Refetoff S. Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency. Endocrinology. 143: 1554-7. PMID 11897715 DOI: 10.1210/Endo.143.4.8828  0.334
2002 Darblade B, Pendaries C, Krust A, Dupont S, Fouque MJ, Rami J, Chambon P, Bayard F, Arnal JF. Estradiol alters nitric oxide production in the mouse aorta through the alpha-, but not beta-, estrogen receptor. Circulation Research. 90: 413-9. PMID 11884370 DOI: 10.1161/Hh0402.105096  0.302
2002 Chapellier B, Mark M, Garnier JM, Dierich A, Chambon P, Ghyselinck NB. A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RARgamma) gene. Genesis (New York, N.Y. : 2000). 32: 95-8. PMID 11857788 DOI: 10.1002/Gene.10072  0.344
2002 Pendaries C, Darblade B, Rochaix P, Krust A, Chambon P, Korach KS, Bayard F, Arnal JF. The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 2205-10. PMID 11854517 DOI: 10.1073/Pnas.042688499  0.351
2002 Ciana P, Vegeto E, Beato M, Chambon P, Gustafsson JA, Parker M, Wahli W, Maggi A. Looking at nuclear receptors from the heights of Erice. Workshop on nuclear receptor structure and function. Embo Reports. 3: 125-9. PMID 11839696 DOI: 10.1093/Embo-Reports/Kvf029  0.372
2002 Crocoll A, Herzer U, Ghyselinck NB, Chambon P, Cato AC. Interdigital apoptosis and downregulation of BAG-1 expression in mouse autopods. Mechanisms of Development. 111: 149-52. PMID 11804787 DOI: 10.1016/S0925-4773(01)00598-6  0.326
2002 Abu-Abed S, MacLean G, Fraulob V, Chambon P, Petkovich M, Dollé P. Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis. Mechanisms of Development. 110: 173-7. PMID 11744378 DOI: 10.1016/S0925-4773(01)00572-X  0.351
2002 Niederreither K, Fraulob V, Garnier JM, Chambon P, Dollé P. Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mechanisms of Development. 110: 165-71. PMID 11744377 DOI: 10.1016/S0925-4773(01)00561-5  0.333
2001 Weber P, Metzger D, Chambon P. Temporally controlled targeted somatic mutagenesis in the mouse brain. The European Journal of Neuroscience. 14: 1777-83. PMID 11860472 DOI: 10.1046/J.0953-816X.2001.01803.X  0.328
2001 Yagishita N, Yamamoto Y, Yoshizawa T, Sekine K, Uematsu Y, Murayama H, Nagai Y, Krezel W, Chambon P, Matsumoto T, Kato S. Aberrant growth plate development in VDR/RXR gamma double null mutant mice. Endocrinology. 142: 5332-41. PMID 11713233 DOI: 10.1210/Endo.142.12.8544  0.673
2001 Krezel W, Dupont S, Krust A, Chambon P, Chapman PF. Increased anxiety and synaptic plasticity in estrogen receptor beta -deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 12278-82. PMID 11593044 DOI: 10.1073/Pnas.221451898  0.662
2001 MacLean G, Abu-Abed S, Dollé P, Tahayato A, Chambon P, Petkovich M. Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development. Mechanisms of Development. 107: 195-201. PMID 11520679 DOI: 10.1016/S0925-4773(01)00463-4  0.346
2001 Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W. Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. The Journal of Cell Biology. 154: 799-814. PMID 11514592 DOI: 10.1083/Jcb.200011148  0.545
2001 Romand R, Albuisson E, Niederreither K, Fraulob V, Chambon P, Dollé P. Specific expression of the retinoic acid-synthesizing enzyme RALDH2 during mouse inner ear development. Mechanisms of Development. 106: 185-9. PMID 11472854 DOI: 10.1016/S0925-4773(01)00447-6  0.394
2001 Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh H, Aster JC, Krishna S, Metzger D, Chambon P, Miele L, Aguet M, Radtke F, Dotto GP. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. The Embo Journal. 20: 3427-36. PMID 11432830 DOI: 10.1093/Emboj/20.13.3427  0.349
2001 Dilworth FJ, Chambon P. Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription. Oncogene. 20: 3047-54. PMID 11420720 DOI: 10.1038/Sj.Onc.1204329  0.357
2001 Angrand PO, Apiou F, Stewart AF, Dutrillaux B, Losson R, Chambon P. NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines. Genomics. 74: 79-88. PMID 11374904 DOI: 10.1006/Geno.2001.6524  0.351
2001 Beckstead R, Ortiz JA, Sanchez C, Prokopenko SN, Chambon P, Losson R, Bellen HJ. Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription. Molecular Cell. 7: 753-65. PMID 11336699 DOI: 10.1016/S1097-2765(01)00220-9  0.384
2001 Metzger D, Chambon P. Site- and time-specific gene targeting in the mouse. Methods (San Diego, Calif.). 24: 71-80. PMID 11327805 DOI: 10.1006/Meth.2001.1159  0.387
2001 Imai T, Jiang M, Kastner P, Chambon P, Metzger D. Selective ablation of retinoid X receptor alpha in hepatocytes impairs their lifespan and regenerative capacity. Proceedings of the National Academy of Sciences of the United States of America. 98: 4581-4586. PMID 11287642 DOI: 10.1073/Pnas.071056098  0.343
2001 Desreumaux P, Dubuquoy L, Nutten S, Peuchmaur M, Englaro W, Schoonjans K, Derijard B, Desvergne B, Wahli W, Chambon P, Leibowitz MD, Colombel J, Auwerx J. Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies. Journal of Experimental Medicine. 193: 827-838. PMID 11283155 DOI: 10.1084/Jem.193.7.827  0.358
2001 Vallier L, Mancip J, Markossian S, Lukaszewicz A, Dehay C, Metzger D, Chambon P, Samarut J, Savatier P. An efficient system for conditional gene expression in embryonic stem cells and in their in vitro and in vivo differentiated derivatives. Proceedings of the National Academy of Sciences of the United States of America. 98: 2467-2472. PMID 11226262 DOI: 10.1073/Pnas.041617198  0.4
2001 Kastner P, Lawrence HJ, Waltzinger C, Ghyselinck NB, Chambon P, Chan S. Positive and negative regulation of granulopoiesis by endogenous RARalpha. Blood. 97: 1314-20. PMID 11222375 DOI: 10.1182/Blood.V97.5.1314  0.4
2001 Abrink M, Ortiz JA, Mark C, Sanchez C, Looman C, Hellman L, Chambon P, Losson R. Conserved interaction between distinct Krüppel-associated box domains and the transcriptional intermediary factor 1 beta. Proceedings of the National Academy of Sciences of the United States of America. 98: 1422-6. PMID 11171966 DOI: 10.1073/Pnas.041616998  0.34
2001 Abu-Abed S, Dollé P, Metzger D, Beckett B, Chambon P, Petkovich M. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes & Development. 15: 226-40. PMID 11157778 DOI: 10.1101/Gad.855001  0.591
2001 Brouchet L, Krust A, Dupont S, Chambon P, Bayard F, Arnal JF. Estradiol Accelerates Reendothelialization in Mouse Carotid Artery Through Estrogen Receptor-α but Not Estrogen Receptor-β Circulation. 103: 423-428. PMID 11157695 DOI: 10.1161/01.Cir.103.3.423  0.331
2001 Imai T, Jiang M, Chambon P, Metzger D. Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 224-228. DOI: 10.1073/Pnas.98.1.224  0.383
2000 Indra AK, Li M, Brocard J, Warot X, Bornert JM, Gérard C, Messaddeq N, Chambon P, Metzger D. Targeted somatic mutagenesis in mouse epidermis. Hormone Research. 54: 296-300. PMID 11595821 DOI: 10.1159/000053275  0.318
2000 Benecke A, Chambon P, Gronemeyer H. Synergy between estrogen receptor α activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2 Embo Reports. 1: 151-157. PMID 11265755 DOI: 10.1093/Embo-Reports/Kvd028  0.355
2000 Bultman S, Gebuhr T, Yee D, La Mantia C, Nicholson J, Gilliam A, Randazzo F, Metzger D, Chambon P, Crabtree G, Magnuson T. A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Molecular Cell. 6: 1287-95. PMID 11163203 DOI: 10.1016/S1097-2765(00)00127-1  0.335
2000 Martin MB, Franke TF, Stoica GE, Chambon P, Katzenellenbogen BS, Stoica BA, McLemore MS, Olivo SE, Stoica A. A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I Endocrinology. 141: 4503-4511. PMID 11108261 DOI: 10.1210/Endo.141.12.7836  0.327
2000 Massaro GD, Massaro D, Chan WY, Clerch LB, Ghyselinck N, Chambon P, Chandraratna RA. Retinoic acid receptor-beta: an endogenous inhibitor of the perinatal formation of pulmonary alveoli. Physiological Genomics. 4: 51-7. PMID 11074013 DOI: 10.1152/Physiolgenomics.2000.4.1.51  0.343
2000 Chiba H, Chambon P, Metzger D. F9 Embryonal Carcinoma Cells Engineered for Tamoxifen-Dependent Cre-Mediated Site-Directed Mutagenesis and Doxycycline-Inducible Gene Expression Experimental Cell Research. 260: 334-339. PMID 11035928 DOI: 10.1006/Excr.2000.5022  0.364
2000 Li M, Indra AK, Warot X, Brocard J, Messaddeq N, Kato S, Metzger D, Chambon P. Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis. Nature. 407: 633-6. PMID 11034212 DOI: 10.1038/35036595  0.375
2000 Kühbandner S, Brummer S, Metzger D, Chambon P, Hofmann F, Feil R. Temporally controlled somatic mutagenesis in smooth muscle Genesis. 28: 15-22. PMID 11020712 DOI: 10.1002/1526-968X(200009)28:1<15::Aid-Gene20>3.0.Co;2-C  0.326
2000 Rochette-Egly C, Plassat J, Taneja R, Chambon P. The AF-1 and AF-2 Activating Domains of Retinoic Acid Receptor-α (RARα) and Their Phosphorylation Are Differentially Involved in Parietal Endodermal Differentiation of F9 Cells and Retinoid-Induced Expression of Target Genes Molecular Endocrinology. 14: 1398-1410. PMID 10976918 DOI: 10.1210/Mend.14.9.0527  0.335
2000 Romand R, Sapin V, Ghyselinck NB, Avan P, Le Calvez S, Dollé P, Chambon P, Mark M. Spatio-temporal distribution of cellular retinoid binding protein gene transcripts in the developing and the adult cochlea. Morphological and functional consequences in CRABP- and CRBPI-null mutant mice. The European Journal of Neuroscience. 12: 2793-804. PMID 10971621 DOI: 10.1046/J.1460-9568.2000.00165.X  0.626
2000 Cammas F, Garnier J, Chambon P, Losson R. Correlation of the exon/intron organization to the conserved domains of the mouse transcriptional corepressor TIF1β ☆ Gene. 253: 231-235. PMID 10940561 DOI: 10.1016/S0378-1119(00)00263-8  0.334
2000 Bourguet W, Vivat V, Wurtz JM, Chambon P, Gronemeyer H, Moras D. Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains Molecular Cell. 5: 289-298. PMID 10882070 DOI: 10.1016/S1097-2765(00)80424-4  0.319
2000 Brown NS, Smart A, Sharma V, Brinkmeier ML, Greenlee L, Camper SA, Jensen DR, Eckel RH, Krezel W, Chambon P, Haugen BR. Thyroid hormone resistance and increased metabolic rate in the RXR-γ- deficient mouse Journal of Clinical Investigation. 106: 73-79. PMID 10880050 DOI: 10.1172/Jci9422  0.669
2000 Bourguet W, Andry V, Iltis C, Klaholz B, Potier N, Van Dorsselaer A, Chambon P, Gronemeyer H, Moras D. Heterodimeric complex of RAR and RXR nuclear receptor ligand-binding domains: Purification, crystallization, and preliminary X-ray diffraction analysis Protein Expression and Purification. 19: 284-288. PMID 10873543 DOI: 10.1006/Prep.2000.1248  0.307
2000 Kopf E, Plassat J, Vivat V, Chambon P, Rochette-Egly C. Dimerization with Retinoid X Receptors and Phosphorylation Modulate the Retinoic Acid-induced Degradation of Retinoic Acid Receptors α and γ through the Ubiquitin-Proteasome Pathway Journal of Biological Chemistry. 275: 33280-33288. PMID 10869350 DOI: 10.1074/Jbc.M002840200  0.335
2000 Mollard R, Viville S, Ward SJ, Décimo D, Chambon P, Dollé P. Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo. Mechanisms of Development. 94: 223-32. PMID 10842077 DOI: 10.1016/S0925-4773(00)00303-8  0.378
2000 Egea PF, Mitschler A, Rochel N, Ruff M, Chambon P, Moras D. Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid. The Embo Journal. 19: 2592-601. PMID 10835357 DOI: 10.1093/Emboj/19.11.2592  0.349
2000 Bastien J, Adam-Stitah S, Riedl T, Egly JM, Chambon P, Rochette-Egly C. TFIIH interacts with the retinoic acid receptor γ and phosphorylates its AF-1-activating domain through cdk7 Journal of Biological Chemistry. 275: 21896-21904. PMID 10748061 DOI: 10.1074/Jbc.M001985200  0.314
2000 Sapin V, Bouillet P, Oulad-Abdelghani M, Dastugue B, Chambon P, Dollé P. Differential expression of retinoic acid-inducible (Stra) genes during mouse placentation. Mechanisms of Development. 92: 295-9. PMID 10727869 DOI: 10.1016/S0925-4773(00)00241-0  0.65
2000 Imai T, Chambon P, Metzger D. Inducible site-specific somatic mutagenesis in mouse hepatocytes. Genesis. 26: 147-148. PMID 10686613 DOI: 10.1002/(Sici)1526-968X(200002)26:2<147::Aid-Gene15>3.0.Co;2-3  0.324
2000 Subbarayan V, Mark M, Messadeq N, Rustin P, Chambon P, Kastner P. RXRα overexpression in cardiomyocytes causes dilated cardiomyopathy but fails to rescue myocardial hypoplasia in RXRα-null fetuses Journal of Clinical Investigation. 105: 387-394. PMID 10675365 DOI: 10.1172/Jci8150  0.337
1999 Nielsen AL, Ortiz JA, You J, Oulad-Abdelghani M, Khechumian R, Gansmuller A, Chambon P, Losson R. Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. The Embo Journal. 18: 6385-95. PMID 10562550 DOI: 10.1093/Emboj/18.22.6385  0.312
1999 Indra AK, Warot X, Brocard J, Bornert JM, Xiao JH, Chambon P, Metzger D. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Research. 27: 4324-7. PMID 10536138 DOI: 10.1093/Nar/27.22.4324  0.318
1999 Delva L, Bastie J, Rochette-Egly C, Kraïba R, Balitrand N, Despouy G, Chambon P, Chomienne C. Physical and Functional Interactions between Cellular Retinoic Acid Binding Protein II and the Retinoic Acid-Dependent Nuclear Complex Molecular and Cellular Biology. 19: 7158-7167. PMID 10490651 DOI: 10.1128/Mcb.19.10.7158  0.383
1999 Ghyselinck NB, Båvik C, Sapin V, Mark M, Bonnier D, Hindelang C, Dierich A, Nilsson CB, Håkansson H, Sauvant P, Azaïs‐Braesco V, Frasson M, Picaud S, Chambon P. Cellular retinol-binding protein I is essential for vitamin A homeostasis. The Embo Journal. 18: 4903-4914. PMID 10487743 DOI: 10.1093/Emboj/18.18.4903  0.321
1999 Géhin M, Vivat V, Wurtz JM, Losson R, Chambon P, Moras D, Gronemeyer H. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists Chemistry and Biology. 6: 519-529. PMID 10421757 DOI: 10.1016/S1074-5521(99)80084-2  0.351
1999 Adam-Stitah S, Penna L, Chambon P, Rochette-Egly C. Hyperphosphorylation of the Retinoid X Receptor α by Activated c-Jun NH2-terminal Kinases Journal of Biological Chemistry. 274: 18932-18941. PMID 10383391 DOI: 10.1074/Jbc.274.27.18932  0.323
1999 Kreżel W, Kastner P, Chambon P. Differential expression of retinoid receptors in the adult mouse central nervous system. Neuroscience. 89: 1291-1300. PMID 10362315 DOI: 10.1016/S0306-4522(98)00342-X  0.684
1999 Davenne M, Maconochie MK, Neun R, Pattyn A, Chambon P, Krumlauf R, Rijli FM. Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain. Neuron. 22: 677-91. PMID 10230789 DOI: 10.1016/S0896-6273(00)80728-X  0.593
1999 Gaudon C, Chambon P, Losson R. Role of the essential yeast protein PSU1 in transcriptional enhancement by the ligand‐dependent activation function AF‐2 of nuclear receptors The Embo Journal. 18: 2229-2240. PMID 10205176 DOI: 10.1093/Emboj/18.8.2229  0.401
1999 Niederreither K, Subbarayan V, Dollé P, Chambon P. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nature Genetics. 21: 444-8. PMID 10192400 DOI: 10.1038/7788  0.6
1999 Xiao JH, Feng X, Di W, Peng ZH, Li LA, Chambon P, Voorhees JJ. Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors. The Embo Journal. 18: 1539-48. PMID 10075925 DOI: 10.1093/Emboj/18.6.1539  0.406
1999 Dupé V, Ghyselinck NB, Thomazy V, Nagy L, Davies PJ, Chambon P, Mark M. Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Developmental Biology. 208: 30-43. PMID 10075839 DOI: 10.1006/Dbio.1998.9176  0.404
1999 Venturini L, You J, Stadler M, Galien R, Lallemand V, Koken MHM, Mattei MG, Ganser A, Chambon P, Losson R, De Thé H. TIF1γ, a novel member of the Transcriptional Intermediary Factor 1 family Oncogene. 18: 1209-1217. PMID 10022127 DOI: 10.1038/Sj.Onc.1202655  0.37
1999 Wendling O, Chambon P, Mark M. Retinoid X receptors are essential for early mouse development and placentogenesis Proceedings of the National Academy of Sciences of the United States of America. 96: 547-551. PMID 9892670 DOI: 10.1073/Pnas.96.2.547  0.358
1998 Barros AC, Erway LC, Krezel W, Curran T, Kastner P, Chambon P, Forrest D. Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis. Neuroreport. 9: 2933-7. PMID 9804293 DOI: 10.1097/00001756-199809140-00003  0.672
1998 Niederreither K, Harbers M, Chambon P, Dollé P. Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis. Oncogene. 17: 1577-85. PMID 9794235 DOI: 10.1038/Sj.Onc.1202072  0.619
1998 Gaub M, Lutz Y, Ghyselinck NB, Scheuer I, Pfister V, Chambon P, Rochette-Egly C. Nuclear detection of cellular retinoic acid binding proteins I and II with new antibodies. Journal of Histochemistry and Cytochemistry. 46: 1103-1111. PMID 9742066 DOI: 10.1177/002215549804601002  0.324
1998 Brocard J, Feil R, Chambon P, Metzger D. A chimeric Cre recombinase inducible by synthetic, but not by natural ligands of the glucocorticoid receptor Nucleic Acids Research. 26: 4086-4090. PMID 9705523 DOI: 10.1093/Nar/26.17.4086  0.359
1998 Le Douarin B, You J, Nielsen AL, Chambon P, Losson R. TIF1α: A possible link between KRAB zinc finger proteins and nuclear receptors Journal of Steroid Biochemistry and Molecular Biology. 65: 43-50. PMID 9699856 DOI: 10.1016/S0960-0760(97)00175-1  0.353
1998 Blanchet S, Favier B, Chevalier G, Michaille J, Dhouailly D, Kastner P, Chambon P. Both Retinoic Acid Receptors α (RARα) and γ (RARγ) Are Able to Initiate Mouse Upper-Lip Skin Glandular Metaplasia Journal of Investigative Dermatology. 111: 206-212. PMID 9699718 DOI: 10.1046/J.1523-1747.1998.00275.X  0.334
1998 Um S, Harbers M, Benecke A, Pierrat B, Losson R, Chambon P. Retinoic Acid Receptors Interact Physically and Functionally with the T:G Mismatch-specific Thymine-DNA Glycosylase* Journal of Biological Chemistry. 273: 20728-20736. PMID 9694815 DOI: 10.1074/Jbc.273.33.20728  0.369
1998 Rijli FM, Gavalas A, Chambon P. Segmentation and specification in the branchial region of the head: the role of the Hox selector genes. The International Journal of Developmental Biology. 42: 393-401. PMID 9654024  0.599
1998 Fraser RA, Heard DJ, Adam S, Lavigne AC, Douarin BL, Tora L, Losson R, Rochette-Egly C, Chambon P. The Putative Cofactor TIF1α Is a Protein Kinase That Is Hyperphosphorylated upon Interaction with Liganded Nuclear Receptors Journal of Biological Chemistry. 273: 16199-16204. PMID 9632676 DOI: 10.1074/Jbc.273.26.16199  0.352
1998 Huang N, Baur Ev, Garnier J, Lerouge T, Vonesch J, Lutz Y, Chambon P, Losson R. Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators The Embo Journal. 17: 3398-3412. PMID 9628876 DOI: 10.1093/Emboj/17.12.3398  0.36
1998 Baur Ev, Harbers M, Um S, Benecke A, Chambon P, Losson R. The yeast Ada complex mediates the ligand-dependent activation function AF-2 of retinoid X and estrogen receptors Genes & Development. 12: 1278-1289. PMID 9573045 DOI: 10.1101/Gad.12.9.1278  0.347
1998 Mark M, Ghyselinck NB, Kastner P, Dupé V, Wendling O, Krezel W, Mascrez B, Chambon P. Mesectoderm is a major target of retinoic acid action. European Journal of Oral Sciences. 106: 24-31. PMID 9541199 DOI: 10.1111/J.1600-0722.1998.Tb02149.X  0.706
1998 Klaholz BP, Renaud JP, Mitschler A, Zusi C, Chambon P, Gronemeyer H, Moras D. Conformational adaptation of agonists to the human nuclear receptor RAR gamma. Nature Structural Biology. 5: 199-202. PMID 9501913 DOI: 10.1038/Nsb0398-199  0.3
1998 Oulad-Abdelghani M, Chazaud C, Bouillet P, Mattei MG, Dollé P, Chambon P. Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily. The International Journal of Developmental Biology. 42: 23-32. PMID 9496783  0.591
1998 El WKŻ, Ghyselinck N, Samad TA, Dupe V, Kastner P, Borrelli E, Chambon P. Impaired Locomotion and Dopamine Signaling in Retinoid Receptor Mutant Mice Science. 279: 863-867. PMID 9452386 DOI: 10.1126/Science.279.5352.863  0.333
1998 Voegel JJ, Heine MJ, Tini M, Vivat V, Chambon P, Gronemeyer H. The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways. The Embo Journal. 17: 507-19. PMID 9430642 DOI: 10.1093/Emboj/17.2.507  0.315
1998 Rijli FM, Gavalas A, Chambon P. Segmentation and specification in the branchial region of the head: the role of the Hox selector genes. The International Journal of Developmental Biology. 42: 393-401. DOI: 10.1387/Ijdb.9654024  0.349
1998 Oulad-Abdelghani M, Chazaud C, Bouillet P, Mattei MG, Dolle P, Chambon P. Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily. The International Journal of Developmental Biology. 42: 23-32. DOI: 10.1387/Ijdb.9496783  0.381
1998 Labrecque J, Allan D, Chambon P, Iscove NN, Lohnes D, Hoang T. Impaired Granulocytic Differentiation In Vitro in Hematopoietic Cells Lacking Retinoic Acid Receptors α1 and γ Blood. 92: 607-615. DOI: 10.1182/Blood.V92.2.607  0.344
1998 Sapin V, Bègue R, Dastugue B, Chambon P, Dollé P. Retinoids and mouse placentation Placenta. 19: 57-76. DOI: 10.1016/S0143-4004(98)80033-7  0.626
1998 Ghyselinck NB, Wendling O, Messaddeq N, Dierich A, Lampron C, Décimo D, Viville S, Chambon P, Mark M. Contribution of retinoic acid receptor β isoforms to the formation of the conotruncal septum of the embryonic heart Developmental Biology. 198: 303-318. DOI: 10.1016/S0012-1606(98)80007-9  0.336
1997 Brocard J, Warot X, Wendling O, Messaddeq N, Vonesch J, Chambon P, Metzger D. Spatio-temporally controlled site-specific somatic mutagenesis in the mouse Proceedings of the National Academy of Sciences of the United States of America. 94: 14559-14563. PMID 9405652 DOI: 10.1073/Pnas.94.26.14559  0.394
1997 Samad TA, Krezel W, Chambon P, Borrelli E. Regulation of dopaminergic pathways by retinoids: Activation of the D2 receptor promoter by members of the retinoic acid receptor–retinoid X receptor family Proceedings of the National Academy of Sciences of the United States of America. 94: 14349-14354. PMID 9405615 DOI: 10.1073/Pnas.94.26.14349  0.702
1997 Mark M, Rijli FM, Chambon P. Homeobox genes in embryogenesis and pathogenesis. Pediatric Research. 42: 421-9. PMID 9380431 DOI: 10.1203/00006450-199710000-00001  0.645
1997 Subbarayan V, Kastner P, Mark M, Dierich A, Gorry P, Chambon P. Limited specificity and large overlap of the functions of the mouse RARγ1 and RARγ2 isoforms Mechanisms of Development. 66: 131-142. PMID 9376317 DOI: 10.1016/S0925-4773(97)00098-1  0.345
1997 Sapin V, Dollé P, Hindelang C, Kastner P, Chambon P. Defects of the chorioallantoic placenta in mouse RXRα null fetuses Developmental Biology. 191: 29-41. PMID 9356169 DOI: 10.1006/Dbio.1997.8687  0.608
1997 Chiba H, Clifford J, Metzger D, Chambon P. Specific and Redundant Functions of Retinoid X Receptor/Retinoic Acid Receptor Heterodimers in Differentiation, Proliferation, and Apoptosis of F9 Embryonal Carcinoma Cells Journal of Cell Biology. 139: 735-747. PMID 9348290 DOI: 10.1083/Jcb.139.3.735  0.378
1997 Oulad-Abdelghani M, Chazaud C, Bouillet P, Sapin V, Chambon P, Dollé P. Meis2, a novel mouse Pbx-related homeobox gene induced by retinoic acid during differentiation of P19 embryonal carcinoma cells Developmental Dynamics. 210: 173-183. PMID 9337137 DOI: 10.1002/(Sici)1097-0177(199710)210:2<173::Aid-Aja9>3.0.Co;2-D  0.634
1997 Sumi-Ichinose C, Ichinose H, Metzger D, Chambon P. SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells. Molecular and Cellular Biology. 17: 5976-5986. PMID 9315656 DOI: 10.1128/Mcb.17.10.5976  0.393
1997 Ward SJ, Chambon P, Ong DE, BÃ¥vik C. A retinol-binding protein receptor-mediated mechanism for uptake of vitamin A to postimplantation rat embryos. Biology of Reproduction. 57: 751-5. PMID 9314576 DOI: 10.1095/Biolreprod57.4.751  0.317
1997 Vivat V, Zechel C, Wurtz JM, Bourguet W, Kagechika H, Umemiya H, Shudo K, Moras D, Gronemeyer H, Chambon P. A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers. The Embo Journal. 16: 5697-709. PMID 9312028 DOI: 10.1093/Emboj/16.18.5697  0.365
1997 Rijli FM, Chambon P. Genetic interactions of Hox genes in limb development: learning from compound mutants. Current Opinion in Genetics & Development. 7: 481-7. PMID 9309178 DOI: 10.1016/S0959-437X(97)80074-3  0.623
1997 Feil R, Wagner J, Metzger D, Chambon P. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochemical and Biophysical Research Communications. 237: 752-757. PMID 9299439 DOI: 10.1006/Bbrc.1997.7124  0.347
1997 Boudjelal M, Taneja R, Matsubara S, Bouillet P, Dollé P, Chambon P. Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells Genes and Development. 11: 2052-2065. PMID 9284045 DOI: 10.1101/Gad.11.16.2052  0.63
1997 Rochette-Egly C, Adam S, Rossignol M, Egly J, Chambon P. Stimulation of RARα Activation Function AF-1 through Binding to the General Transcription Factor TFIIH and Phosphorylation by CDK7 Cell. 90: 97-107. PMID 9230306 DOI: 10.1016/S0092-8674(00)80317-7  0.301
1997 Murcia JMd, Niedergang C, Trucco C, Ricoul M, Dutrillaux B, Mark M, Oliver FJ, Masson M, Dierich A, LeMeur M, Walztinger C, Chambon P, Murcia Gd. Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells Proceedings of the National Academy of Sciences of the United States of America. 94: 7303-7307. PMID 9207086 DOI: 10.1073/Pnas.94.14.7303  0.328
1997 Bouillet P, Sapin V, Chazaud C, Messaddeq N, Décimo D, Dollé P, Chambon P. Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein Mechanisms of Development. 63: 173-186. PMID 9203140 DOI: 10.1016/S0925-4773(97)00039-7  0.624
1997 Mengus G, May M, Carré L, Chambon P, Davidson I. Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells. Genes & Development. 11: 1381-95. PMID 9192867 DOI: 10.1101/Gad.11.11.1381  0.324
1997 Le Douarin B, Nielsen AL, You J, Chambon P, Losson R. TIF1α: A chromatin-specific mediator for the ligand-dependent activation function AF-2 of nuclear receptors? Biochemical Society Transactions. 25: 605-612. PMID 9191165 DOI: 10.1042/Bst0250605  0.329
1997 Chiba H, Clifford J, Metzger D, Chambon P. Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells. Molecular and Cellular Biology. 17: 3013-3020. PMID 9154799 DOI: 10.1128/Mcb.17.6.3013  0.388
1997 Umemiya H, Kagechika H, Fukasawa H, Kawachi E, Ebisawa M, Hashimoto Y, Eisenmann G, Erb C, Pornon A, Chambon P, Gronemeyer H, Shudo K. Action mechanism of retinoid-synergistic dibenzodiazepines. Biochemical and Biophysical Research Communications. 233: 121-125. PMID 9144408 DOI: 10.1006/Bbrc.1997.6414  0.398
1997 Niederreither K, McCaffery P, Dräger UC, Chambon P, Dollé P. Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development. Mechanisms of Development. 62: 67-78. PMID 9106168 DOI: 10.1016/S0925-4773(96)00653-3  0.382
1997 Ichinose H, Garnier J, Chambon P, Losson R. Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2 Gene. 188: 95-100. PMID 9099865 DOI: 10.1016/S0378-1119(96)00785-8  0.367
1997 Fraser RA, Rossignol M, Heard DJ, Egly J, Chambon P. SUG1, a Putative Transcriptional Mediator and Subunit of the PA700 Proteasome Regulatory Complex, Is a DNA Helicase Journal of Biological Chemistry. 272: 7122-7126. PMID 9054406 DOI: 10.1074/Jbc.272.11.7122  0.341
1997 Sapin V, Ward SJ, Bronner S, Chambon P, Dollé P. Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 208: 199-210. PMID 9022057 DOI: 10.1002/(Sici)1097-0177(199702)208:2<199::Aid-Aja7>3.0.Co;2-D  0.404
1997 Feng X, Peng ZH, Di W, Li XY, Rochette-Egly C, Chambon P, Voorhees JJ, Xiao JH. Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids. Genes & Development. 11: 59-71. PMID 9000050 DOI: 10.1101/Gad.11.1.59  0.387
1997 Ghyselinck NB, Dupe V, Dierich A, Messaddeq N, Garnier JM, Rochette-Egly C, Chambon P, Mark M. Role of the retinoic acid receptor beta (RARbeta) during mouse development. The International Journal of Developmental Biology. 41: 425-447. DOI: 10.1387/Ijdb.9240560  0.305
1996 Roux S, Térouanne B, Balaguer P, Jausons-Loffreda N, Pons M, Chambon P, Gronemeyer H, Nicolas JC. Mutation of isoleucine 747 by a threonine alters the ligand responsiveness of the human glucocorticoid receptor. Molecular Endocrinology. 10: 1214-1226. PMID 9121489 DOI: 10.1210/Mend.10.10.9121489  0.33
1996 Brocard J, Kastner P, Chambon P. Two Novel RXRα Isoforms from Mouse Testis Biochemical and Biophysical Research Communications. 229: 211-218. PMID 8954108 DOI: 10.1006/Bbrc.1996.1782  0.362
1996 Oulad-Abdelghani M, Bouillet P, Décimo D, Gansmuller A, Heyberger S, Dollé P, Bronner S, Lutz Y, Chambon P. Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene. The Journal of Cell Biology. 135: 469-77. PMID 8896602 DOI: 10.1083/Jcb.135.2.469  0.628
1996 Bouillet P, Oulad-Abdelghani M, Ward SJ, Bronner S, Chambon P, Dollé P. A new mouse member of the Wnt gene family, mWnt-8, is expressed during early embryogenesis and is ectopically induced by retinoic acid. Mechanisms of Development. 58: 141-52. PMID 8887323 DOI: 10.1016/S0925-4773(96)00569-2  0.39
1996 Nakshatri H, Bouillet P, Bhat-Nakshatri P, Chambon P. Isolation of retinoic acid-repressed genes from P19 embryonal carcinoma cells Gene. 174: 79-84. PMID 8863732 DOI: 10.1016/0378-1119(96)00391-5  0.373
1996 Feil R, Brocard J, Mascrez B, LeMeur M, Metzger D, Chambon P. Ligand-Activated Site-Specific Recombination In Mice Proceedings of the National Academy of Sciences of the United States of America. 93: 10887-10890. PMID 8855277 DOI: 10.1073/Pnas.93.20.10887  0.377
1996 Gérard M, Chen JY, Gronemeyer H, Chambon P, Duboule D, Zákány J. In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries. Genes & Development. 10: 2326-34. PMID 8824591 DOI: 10.1101/Gad.10.18.2326  0.613
1996 Chazaud C, Oulad-Abdelghani M, Bouillet P, Décimo D, Chambon P, Dollé P. AP-2.2, a novel gene related to AP-2, is expressed in the forebrain, limbs and face during mouse embryogenesis Mechanisms of Development. 54: 83-94. PMID 8808408 DOI: 10.1016/0925-4773(95)00463-7  0.621
1996 Taneja R, Thisse B, Rijli FM, Thisse C, Bouillet P, Dollé P, Chambon P. The expression pattern of the mouse receptor tyrosine kinase gene MDK1 is conserved through evolution and requires Hoxa-2 for rhombomere-specific expression in mouse embryos Developmental Biology. 177: 397-412. PMID 8806819 DOI: 10.1006/Dbio.1996.0173  0.753
1996 Krezel W, Dupe V, Mark M, Dierich A, Kastner P, Chambon P. RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable Proceedings of the National Academy of Sciences of the United States of America. 93: 9010-9014. PMID 8799145 DOI: 10.1073/Pnas.93.17.9010  0.663
1996 Chen J, Clifford J, Zusi C, Starrett J, Tortolani D, Ostrowski J, Reczek PR, Chambon P, Gronemeyer H. Two distinct actions of retinoid-receptor ligands. Nature. 382: 819-822. PMID 8752277 DOI: 10.1038/382819A0  0.366
1996 Le Douarin B, vom Baur E, Zechel C, Heery D, Heine M, Vivat V, Gronemeyer H, Losson R, Chambon P. Ligand-dependent interaction of nuclear receptors with potential transcriptional intermediary factors (mediators). Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 351: 569-78. PMID 8735280 DOI: 10.1098/Rstb.1996.0056  0.338
1996 Oulad-Abdelghani M, Bouillet P, Chazaud C, Dollé P, Chambon P. AP-2.2: A novel AP-2-related transcription factor induced by retinoic acid during differentiation of P19 embryonal carcinoma cells Experimental Cell Research. 225: 338-347. PMID 8660922 DOI: 10.1006/Excr.1996.0184  0.625
1996 Niederreither K, Ward SJ, Dollé P, Chambon P. Morphological and molecular characterization of retinoic acid-induced limb duplications in mice. Developmental Biology. 176: 185-98. PMID 8660860 DOI: 10.1006/Dbio.1996.0126  0.33
1996 Taneja R, Roy B, Plassat J, Zusi CF, Ostrowski J, Reczek PR, Chambon P. Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts Proceedings of the National Academy of Sciences of the United States of America. 93: 6197-6202. PMID 8650243 DOI: 10.1073/Pnas.93.12.6197  0.387
1996 BÃ¥vik C, Ward SJ, Chambon P. Developmental abnormalities in cultured mouse embryos deprived of retinoic by inhibition of yolk-sac retinol binding protein synthesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 3110-4. PMID 8610177 DOI: 10.1073/Pnas.93.7.3110  0.325
1996 Bouillet P, Chazaud C, Oulad-Abdelghani M, Dollé P, Chambon P. Sequence and expression pattern of the Stra7 (Gbx-2) homeobox-containing gene induced by retinoic acid in P19 embryonal carcinoma cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 204: 372-82. PMID 8601031 DOI: 10.1002/Aja.1002040404  0.633
1996 Kastner P, Mark M, Leid M, Gansmuller A, Chin W, Grondona JM, Décimo D, Krezel W, Dierich A, Chambon P. Abnormal spermatogenesis in RXR beta mutant mice. Genes & Development. 10: 80-92. PMID 8557197 DOI: 10.1101/Gad.10.1.80  0.683
1996 Wurtz JM, Bourguet W, Renaud JP, Vivat V, Chambon P, Moras D, Gronemeyer H. A canonical structure for the ligand-binding domain of nuclear receptors. Nature Structural Biology. 3: 87-94. PMID 8548460 DOI: 10.1038/Nsb0196-87  0.336
1996 Chambon P. A decade of molecular biology of retinoic acid receptors. The Faseb Journal. 10: 940-954. DOI: 10.1096/Fasebj.10.9.8801176  0.388
1996 Podhajcer OL, Wolf C, Lefebvre O, Segain J-, Rouyer N, Stoll I, Rio M-, Chambon P, Basset P. Comparative expression of the SPARC and stromelysin-3 genes in mammary tumours The Breast. 5: 13-20. DOI: 10.1016/S0960-9776(96)90044-2  0.321
1996 Douarin BL, Nielsen AL, Garnier JM, Ichinose H, Jeanmougin F, Losson R, Chambon P. A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. The Embo Journal. 15: 6701-6715. DOI: 10.1002/J.1460-2075.1996.Tb01060.X  0.389
1996 Clifford J, Chiba H, Sobieszczuk D, Metzger D, Chambon P. RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids. The Embo Journal. 15: 4142-4155. DOI: 10.1002/J.1460-2075.1996.Tb00789.X  0.356
1996 Voegel JJ, Heine MJ, Zechel C, Chambon P, Gronemeyer H. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors The Embo Journal. 15: 3667-3675. DOI: 10.1002/J.1460-2075.1996.Tb00736.X  0.399
1996 May M, Mengus G, Lavigne AC, Chambon P, Davidson I. Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors. The Embo Journal. 15: 3093-3104. DOI: 10.1002/J.1460-2075.1996.Tb00672.X  0.356
1996 Baur EV, Zechel C, Heery D, Heine MJS, Garnier JM, Vivat V, Douarin BL, Gronemeyer H, Chambon P, Losson R. Differential ligand‐dependent interactions between the AF‐2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. The Embo Journal. 15: 110-124. DOI: 10.1002/J.1460-2075.1996.Tb00339.X  0.333
1995 Scheer E, Mattei M, Jacq X, Chambon P, Tora L. Organization and chromosomal localization of the gene (TAF2H) encoding the human TBP-associated factor II 30 (TAFII30). Genomics. 29: 269-272. PMID 8530084 DOI: 10.1006/Geno.1995.1243  0.335
1995 Roy B, Taneja R, Chambon P. Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand. Molecular and Cellular Biology. 15: 6481-6487. PMID 8524212 DOI: 10.1128/Mcb.15.12.6481  0.397
1995 Favier B, Le Meur M, Chambon P, Dollé P. Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice Proceedings of the National Academy of Sciences of the United States of America. 92: 310-314. PMID 7816839 DOI: 10.1073/Pnas.92.1.310  0.601
1995 Bourguet W, Ruff M, Chambon P, Gronemeyer H, Moras D. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature. 375: 377-82. PMID 7760929 DOI: 10.1038/375377A0  0.309
1995 Chambon P. The Molecular and Genetic Dissection of the Retinoid Signaling Pathway Recent Progress in Hormone Research. 50: 317-332. PMID 7740164 DOI: 10.1016/B978-0-12-571150-0.50019-6  0.358
1995 Metzger D, Ali S, Bornert J, Chambon P. Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells Journal of Biological Chemistry. 270: 9535-9542. PMID 7721882 DOI: 10.1074/Jbc.270.16.9535  0.38
1995 Rijli FM, Matyas R, Pellegrini M, Dierich A, Gruss P, Dollé P, Chambon P. Cryptorchidism and homeotic transformations of spinal nerves and vertebrae in Hoxa-10 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 8185-9. PMID 7667266 DOI: 10.1073/Pnas.92.18.8185  0.619
1995 Bouillet P, Oulad-Abdelghani M, Vicaire S, Garnier JM, Schuhbaur B, Dollé P, Chambon P. Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, stral (mouse LERK-2/Eplg2) Developmental Biology. 170: 420-433. PMID 7649373 DOI: 10.1006/Dbio.1995.1226  0.619
1995 Taneja R, Bouillet P, Boylan JF, Gaub MP, Roy B, Gudas LJ, Chambon P. Reexpression of retinoic acid receptor (RAR)γ or overexpression of RARα or RARβ in RARγ-null F9 cells reveals a partial functional redundancy between the three RAR types Proceedings of the National Academy of Sciences of the United States of America. 92: 7854-7858. PMID 7644503 DOI: 10.1073/Pnas.92.17.7854  0.39
1995 Boam DS, Davidson I, Chambon P. A TATA-less promoter containing binding sites for ubiquitous transcription factors mediates cell type-specific regulation of the gene for transcription enhancer factor-1 (TEF-1). The Journal of Biological Chemistry. 270: 19487-94. PMID 7642633 DOI: 10.1074/Jbc.270.33.19487  0.363
1995 Lohnes D, Mark M, Mendelsohn C, Dollé P, Decimo D, LeMeur M, Dierich A, Gorry P, Chambon P. Developmental roles of the retinoic acid receptors Journal of Steroid Biochemistry and Molecular Biology. 53: 475-486. PMID 7626498 DOI: 10.1016/0960-0760(95)00094-G  0.609
1995 Mark M, Lohnes D, Mendelsohn C, Dupé V, Vonesch JL, Kastner P, Rijli F, Bloch-Zupan A, Chambon P. Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton. The International Journal of Developmental Biology. 39: 111-21. PMID 7626396  0.635
1995 Metzger D, Clifford J, Chiba H, Chambon P. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase Proceedings of the National Academy of Sciences of the United States of America. 92: 6991-6995. PMID 7624356 DOI: 10.1073/Pnas.92.15.6991  0.392
1995 Fisher GJ, Reddy AP, Datta SC, Kang S, Yi JY, Chambon P, Voorhees JJ. All-trans retinoic acid induces cellular retinol-binding protein in human skin in vivo. The Journal of Investigative Dermatology. 105: 80-6. PMID 7615982 DOI: 10.1111/1523-1747.Ep12313352  0.327
1995 Kersten S, Pan L, Chambon P, Gronemeyer H, Noy N. Role of ligand in retinoid signaling. 9-cis-retinoic acid modulates the oligomeric state of the retinoid X receptor. Biochemistry. 34: 13717-21. PMID 7577963 DOI: 10.1021/Bi00042A001  0.374
1995 Kersten S, Kelleher D, Chambon P, Gronemeyer H, Noy N. Retinoid X receptor alpha forms tetramers in solution. Proceedings of the National Academy of Sciences of the United States of America. 92: 8645-9. PMID 7567990 DOI: 10.1073/Pnas.92.19.8645  0.361
1995 Metzger D, Berry M, Ali S, Chambon P. Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo. Molecular Endocrinology. 9: 579-591. PMID 7565805 DOI: 10.1210/Mend.9.5.7565805  0.349
1995 Renaud JP, Rochel N, Ruff M, Vivat V, Chambon P, Gronemeyer H, Moras D. Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature. 378: 681-9. PMID 7501014 DOI: 10.1038/378681A0  0.314
1995 Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H, Masushige S, Gotoh Y, Nishida E, Kawashima H, Metzger D, Chambon P. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (New York, N.Y.). 270: 1491-4. PMID 7491495 DOI: 10.1126/Science.270.5241.1491  0.322
1995 Cicatiello L, Cobellis G, Addeo R, Papa M, Altucci L, Sica V, Bresciani F, LeMeur M, Kumar VL, Chambon P. In vivo functional analysis of the mouse estrogen receptor gene promoter: a transgenic mouse model to study tissue-specific and developmental regulation of estrogen receptor gene transcription. Molecular Endocrinology (Baltimore, Md.). 9: 1077-90. PMID 7476981 DOI: 10.1210/Mend.9.8.7476981  0.418
1995 Rochette-Egly C, Oulad-Abdelghani M, Staub A, Pfister V, Scheuer I, Chambon P, Gaub MP. Phosphorylation of the retinoic acid receptor-α by protein kinase A Molecular Endocrinology. 9: 860-871. PMID 7476969 DOI: 10.1210/Mend.9.7.7476969  0.352
1995 Mark M, Lohnes D, Mendelsohn C, Dupe V, Vonesch JL, Kastner P, Rijli F, Bloch-Zupan A, Chambon P. Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton. The International Journal of Developmental Biology. 39: 111-121. DOI: 10.1387/Ijdb.7626396  0.408
1995 Mark M, Rijli FM, Chambon P. Alteration of Hox gene expression in the branchial region of the head causes homeotic transformations, hindbrain segmentation defects and atavistic changes Seminars in Developmental Biology. 6: 275-284. DOI: 10.1016/S1044-5781(06)80053-8  0.629
1995 Douarin BL, Zechel C, Garnier JM, Lutz Y, Tora L, Pierrat P, Heery D, Gronemeyer H, Chambon P, Losson R. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. The Embo Journal. 14: 2020-2033. DOI: 10.1002/J.1460-2075.1995.Tb07194.X  0.382
1995 Mengus G, May M, Jacq X, Staub A, Tora L, Chambon P, Davidson I. Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID. The Embo Journal. 14: 1520-1531. DOI: 10.1002/J.1460-2075.1995.Tb07138.X  0.324
1995 Chen JY, Penco S, Ostrowski J, Balaguer P, Pons M, Starrett JE, Reczek P, Chambon P, Gronemeyer H. RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. The Embo Journal. 14: 1187-1197. DOI: 10.1002/J.1460-2075.1995.Tb07102.X  0.349
1994 Pierrat B, Heery DM, Chambon P, Losson R. A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast Gene. 143: 193-200. PMID 8206373 DOI: 10.1016/0378-1119(94)90096-5  0.375
1994 Dollé P, Fraulob V, Kastner P, Chambon P. Developmental expression of murine retinoid X receptor (RXR) genes Mechanisms of Development. 45: 91-104. PMID 8199055 DOI: 10.1016/0925-4773(94)90023-X  0.636
1994 Heery DM, Pierrat B, Gronemeyer H, Chambon P, Losson R. Homo- and heterodimers of the retinoid X receptor (RXR) activate transcription in yeast Nucleic Acids Research. 22: 726-731. PMID 8139911 DOI: 10.1093/Nar/22.5.726  0.354
1994 Gorry P, Lufkin T, Dierich A, Rochette-Egly C, Décimo D, Dollé P, Mark M, Durand B, Chambon P. The cellular retinoic acid binding protein I is dispensable Proceedings of the National Academy of Sciences of the United States of America. 91: 9032-9036. PMID 8090764 DOI: 10.1073/Pnas.91.19.9032  0.618
1994 Chambon P. The retinoid signaling pathway: molecular and genetic analyses Seminars in Cell Biology. 5: 115-125. PMID 8068884 DOI: 10.1006/Scel.1994.1015  0.388
1994 Chaudhary S, Brou C, Valentin ME, Burton N, Tora L, Chambon P, Davidson I. A cell-specific factor represses stimulation of transcription in vitro by transcriptional enhancer factor 1. Molecular and Cellular Biology. 14: 5290-9. PMID 8035807 DOI: 10.1128/Mcb.14.8.5290  0.33
1994 Vonesch JL, Nakshatri H, Philippe M, Chambon P, Dollé P. Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 199: 199-213. PMID 8018987 DOI: 10.1002/Aja.1001990305  0.637
1994 Ahnen DJ, Poulsom R, Stamp GWH, Elia G, Pike C, Jeffery R, Longcroft J, Rio M, Chambon P, Wright NA. The ulceration-associated cell lineage (UACL) reiterates the Brunner's gland differentiation programme but acquires the proliferative organization of the gastric gland. The Journal of Pathology. 173: 317-326. PMID 7965391 DOI: 10.1002/Path.1711730406  0.318
1994 Mendelsohn C, Mark M, Dollé P, Dierich A, Gaub MP, Krust A, Lampron C, Chambon P. Retinoic acid receptor beta 2 (RAR beta 2) null mutant mice appear normal. Developmental Biology. 166: 246-58. PMID 7958449 DOI: 10.1006/Dbio.1994.1311  0.606
1994 Jacq X, Brou C, Lutz Y, Davidson I, Chambon P, Tora L. Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell. 79: 107-17. PMID 7923369 DOI: 10.1016/0092-8674(94)90404-9  0.349
1994 Kastner P, Grondona JM, Mark M, Gansmuller A, LeMeur M, Decimo D, Vonesch JL, Dollé P, Chambon P. Genetic analysis of RXRα developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis Cell. 78: 987-1003. PMID 7923367 DOI: 10.1016/0092-8674(94)90274-7  0.575
1994 Rijli FM, Dollé P, Fraulob V, LeMeur M, Chambon P. Insertion of a targeting construct in a Hoxd-10 allele can influence the control of Hoxd-9 expression. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 201: 366-77. PMID 7894075 DOI: 10.1002/Aja.1002010408  0.748
1994 Törmä H, Asselineau D, Andersson E, Martin B, Reiniche P, Chambon P, Shroot B, Darmon M, Vahlquist A. Biologic activities of retinoic acid and 3,4-didehydroretinoic acid in human keratinocytes are similar and correlate with receptor affinities and transactivation properties Journal of Investigative Dermatology. 102: 49-54. PMID 7507153 DOI: 10.1111/1523-1747.Ep12371731  0.339
1994 Saurat J, Didierjean L, Lampron C, Lufin T, Gorry P, Carraux P, Tamm K, Chambon P. Distinct alteration in the biological effects of topical retinoic acid and precursors in mice with disrupted genes for cellular retinoic acid binding proteins (CRABP1 and 2) Journal of Investigative Dermatology. 103: 420. DOI: 10.5555/Uri:Pii:0022202X9492323X  0.354
1994 Durand B, Saunders M, Gaudon C, Roy B, Losson R, Chambon P. Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity. The Embo Journal. 13: 5370-5382. DOI: 10.1002/J.1460-2075.1994.Tb06872.X  0.371
1994 Zechel C, Shen X, Chen J, Chen Z, Chambon P, Gronemeyer H. The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats. The Embo Journal. 13: 1425-1433. DOI: 10.1002/J.1460-2075.1994.Tb06396.X  0.343
1994 Zechel C, Shen X, Chambon P, Gronemeyer H. Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements. The Embo Journal. 13: 1414-1424. DOI: 10.1002/J.1460-2075.1994.Tb06395.X  0.352
1994 Lescure A, Lutz Y, Eberhard D, Jacq X, Krol A, Grummt I, Davidson I, Chambon P, Tora L. The N‐terminal domain of the human TATA‐binding protein plays a role in transcription from TATA‐containing RNA polymerase II and III promoters. The Embo Journal. 13: 1166-1175. DOI: 10.1002/J.1460-2075.1994.Tb06366.X  0.314
1993 Bocquel M, Ji J, Ylikomi T, Benhamou B, Vergezac A, Chambon P, Gronemeyer H. Type II antagonists impair the DNA binding of steroid hormone receptors without affecting dimerization The Journal of Steroid Biochemistry and Molecular Biology. 45: 205-215. PMID 8499329 DOI: 10.1016/0960-0760(93)90334-S  0.338
1993 Schaeffer L, Roy R, Humbert S, Moncollin V, Vermeulen W, Hoeijmakers JHJ, Chambon P, Egly J. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor Science. 260: 58-63. PMID 8465201 DOI: 10.1126/Science.8465201  0.341
1993 Wolf C, Rouyer N, Lutz Y, Adida C, Loriot M, Bellocq JP, Chambon P, Basset P. Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 90: 1843-1847. PMID 8446598 DOI: 10.1073/Pnas.90.5.1843  0.303
1993 Brou C, Wu J, Ali S, Scheer E, Lang C, Davidson I, Chambon P, Tora L. Different TBP-associated factors are required for mediating the stimulation of transcription in vitro by the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor. Nucleic Acids Research. 21: 5-12. PMID 8441620 DOI: 10.1093/Nar/21.1.5  0.368
1993 Gilbert DM, Heery DM, Losson R, Chambon P, Lemoine Y. Estradiol-inducible squelching and cell growth arrest by a chimeric VP16-estrogen receptor expressed in Saccharomyces cerevisiae: suppression by an allele of PDR1. Molecular and Cellular Biology. 13: 462-72. PMID 8417344 DOI: 10.1128/mcb.13.1.462-472.1993  0.404
1993 Lufkin T, Lohnes D, Mark M, Dierich A, Gorry P, Gaub MP, LeMeur M, Chambon P. High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 7225-9. PMID 8394014 DOI: 10.1073/Pnas.90.15.7225  0.34
1993 Lohnes D, Kastner P, Dierich A, Mark M, LeMeur M, Chambon P. Function of retinoic acid receptor gamma in the mouse. Cell. 73: 643-58. PMID 8388780 DOI: 10.1016/0092-8674(93)90246-M  0.365
1993 Heery DM, Zacharewski T, Pierrat B, Gronemeyer H, Chambon P, Losson R. Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors. Proceedings of the National Academy of Sciences of the United States of America. 90: 4281-4285. PMID 8387213 DOI: 10.1073/Pnas.90.9.4281  0.387
1993 Mader S, Chambon P, White JH. Defining a minimal estrogen receptor DNA binding domain. Nucleic Acids Research. 21: 1125-32. PMID 8385312 DOI: 10.1093/Nar/21.5.1125  0.586
1993 Leid M, Kastner P, Durand B, Krust A, Leroy P, Lyons R, Mendelsohn C, Nagpal S, Nakshatri H, Reibel C, Saunders M, Chambon P. Retinoic acid signal transduction pathways. Annals of the New York Academy of Sciences. 684: 19-34. PMID 8317828 DOI: 10.1111/J.1749-6632.1993.Tb32268.X  0.353
1993 Lefebvre O, Wolf C, Kédinger M, Chenard M, Tomasetto C, Chambon P, Rio M. The mouse one P-domain (pS2) and two P-domain (mSP) genes exhibit distinct patterns of expression. Journal of Cell Biology. 122: 191-198. PMID 8314841 DOI: 10.1083/Jcb.122.1.191  0.364
1993 Dollé P, Dierich A, LeMeur M, Schimmang T, Schuhbaur B, Chambon P, Duboule D. Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell. 75: 431-41. PMID 8106170 DOI: 10.1016/0092-8674(93)90378-4  0.708
1993 Boylan JF, Lohnes D, Taneja R, Chambon P, Gudas LJ. Loss of retinoic acid receptor γ function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment Proceedings of the National Academy of Sciences of the United States of America. 90: 9601-9605. PMID 8105479 DOI: 10.1073/Pnas.90.20.9601  0.401
1993 Dollé P, Lufkin T, Krumlauf R, Mark M, Duboule D, Chambon P. Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos. Proceedings of the National Academy of Sciences of the United States of America. 90: 7666-70. PMID 8102800 DOI: 10.1073/Pnas.90.16.7666  0.717
1993 Rijli FM, Mark M, Lakkaraju S, Dierich A, Dollé P, Chambon P. A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene Cell. 75: 1333-1349. PMID 7903601 DOI: 10.1016/0092-8674(93)90620-6  0.735
1993 Lohnes D, Dierich A, Ghyselinck N, Kastner P, Lampron C, LeMeur M, Lufkin T, Mendelsohn C, Nakshatri H, Chambon P. Retinoid receptors and binding proteins. Journal of Cell Science. Supplement. 16: 69-76. PMID 1338435 DOI: 10.1242/Jcs.1992.Supplement_16.9  0.385
1993 Mader S, Chen J, Chen Z, White J, Chambon P, Gronemeyer H. The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains. The Embo Journal. 12: 5029-5041. DOI: 10.1002/J.1460-2075.1993.Tb06196.X  0.562
1993 Perez A, Kastner P, Sethi S, Lutz Y, Reibel C, Chambon P. PMLRAR homodimers: Distinct DNA binding properties and heteromeric interactions with RXR The Embo Journal. 12: 3171-3182. DOI: 10.1002/J.1460-2075.1993.Tb05986.X  0.366
1993 Nagpal S, Friant S, Nakshatri H, Chambon P. RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo. The Embo Journal. 12: 2349-2360. DOI: 10.1002/J.1460-2075.1993.Tb05889.X  0.384
1993 Hwang J, Chambon P, Davidson I. Characterization of the transcription activation function and the DNA binding domain of transcriptional enhancer factor-1. The Embo Journal. 12: 2337-2348. DOI: 10.1002/J.1460-2075.1993.Tb05888.X  0.336
1993 Ali S, Metzger D, Bornert J-, Chambon P. Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region. The Embo Journal. 12: 1153-1160. DOI: 10.1002/J.1460-2075.1993.Tb05756.X  0.376
1993 Brou C, Chaudhary S, Davidson I, Lutz Y, Wu J, Egly JM, Tora L, Chambon P. Distinct TFIID complexes mediate the effect of different transcriptional activators. The Embo Journal. 12: 489-499. DOI: 10.1002/J.1460-2075.1993.Tb05681.X  0.32
1992 Kato S, Tora L, Yamauchi J, Masushige S, Bellard M, Chambon P. A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically Cell. 68: 731-742. PMID 1739978 DOI: 10.1016/0092-8674(92)90148-6  0.346
1992 Moncollin V, Fischer L, Cavallini B, Egly J, Chambon P. Class II (B) general transcription factor (TFIIB) that binds to the template-committed preinitiation complex is different from general transcription factor BTF3. Proceedings of the National Academy of Sciences of the United States of America. 89: 397-401. PMID 1729710 DOI: 10.1073/Pnas.89.1.397  0.324
1992 Metzger D, Losson R, Bornert JM, Lemoine Y, Chambon P. Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast. Nucleic Acids Research. 20: 2813-7. PMID 1614867 DOI: 10.1093/Nar/20.11.2813  0.374
1992 Fischer L, Gerard M, Chalut C, Lutz Y, Humbert S, Kanno M, Chambon P, Egly J. Cloning of the 62-Kilodalton Component of Basic Transcription Factor BTF2 Science. 257: 1392-1395. PMID 1529339 DOI: 10.1126/Science.1529339  0.3
1992 Wolf C, Chenard M, Grossouvre PDd, Bellocq J, Chambon P, Basset P. Breast-cancer-associated stromelysin-3 gene is expressed in basal cell carcinoma and during cutaneous wound healing. Journal of Investigative Dermatology. 99: 870-872. PMID 1469302 DOI: 10.1111/1523-1747.Ep12614846  0.331
1992 Gilbert DM, Losson R, Chambon P. Ligand dependence of estrogen receptor induced changes in chromatin structure. Nucleic Acids Research. 20: 4525-4531. PMID 1408752 DOI: 10.1093/Nar/20.17.4525  0.341
1992 Benhamou B, Garcia T, Lerouge T, Vergezac A, Gofflo D, Bigogne C, Chambon P, Gronemeyer H. A single amino acid that determines the sensitivity of progesterone receptors to RU486 Science. 255: 206-209. PMID 1372753 DOI: 10.1126/Science.1372753  0.336
1992 Lufkin T, Mark M, Hart CP, Dollé P, Lemeur M, Chambon P. Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene Nature. 359: 835-841. PMID 1359423 DOI: 10.1038/359835A0  0.613
1992 Mendelsohn C, Ruberte E, Chambon P. Retinoid receptors in vertebrate limb development. Developmental Biology. 152: 50-61. PMID 1352757 DOI: 10.1016/0012-1606(92)90155-A  0.345
1992 Garcia T, Benhamou B, Gofflo D, Vergezac A, Philibert D, Chambon P, Gronemeyer H. Switching agonistic, antagonistic, and mixed transcriptional responses to 11 beta-substituted progestins by mutation of the progesterone receptor. Molecular Endocrinology. 6: 2071-2078. PMID 1337143 DOI: 10.1210/Mend.6.12.1337143  0.354
1992 Leid M, Kastner P, Chambon P. Multiplicity generates diversity in the retinoic acid signalling pathways Trends in Biochemical Sciences. 17: 427-433. PMID 1333659 DOI: 10.1016/0968-0004(92)90014-Z  0.339
1992 Duell EA, Aström A, Griffiths CEM, Chambon P, Voorhees JJ. Human skin levels of retinoic acid and cytochrome P-450-derived 4-hydroxyretinoic acid after topical application of retinoic acid in vivo compared to concentrations required to stimulate retinoic acid receptor-mediated transcription in vitro Journal of Clinical Investigation. 90: 1269-1274. PMID 1328295 DOI: 10.1172/Jci115990  0.333
1992 Durand B, Saunders M, Leroy P, Leid M, Chambon P. All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs. Cell. 71: 73-85. PMID 1327537 DOI: 10.1016/0092-8674(92)90267-G  0.367
1992 Nagpal S, Saunders M, Kastner P, Durand B, Nakshatri H, Chambon P. Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors Cell. 70: 1007-1019. PMID 1326406 DOI: 10.1016/0092-8674(92)90250-G  0.388
1992 Costa-Giomi MP, Gaub MP, Chambon P, Abarzúa P. Characterization of a retinoic acid responsive element isolated by whole genome PCR Nucleic Acids Research. 20: 3223-3232. PMID 1320257 DOI: 10.1093/Nar/20.12.3223  0.329
1992 Elder JT, Aström A, Pettersson U, Tavakkol A, Krust A, Kastner P, Chambon P, Voorhees JJ. Retinoic acid receptors and binding proteins in human skin. The Journal of Investigative Dermatology. 98: 36S-41S. PMID 1316927 DOI: 10.1111/1523-1747.Ep12462180  0.376
1992 Pauly M, Treger M, Westhof E, Chambon P. The initiation accuracy of the SV40 early transcription is determined by the functional domains of two TATA elements. Nucleic Acids Research. 20: 975-982. PMID 1312710 DOI: 10.1093/Nar/20.5.975  0.328
1992 Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T, Chen JY, Staub A, Garnier JM, Mader S, Chambon P. Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently Cell. 68: 377-395. PMID 1310259 DOI: 10.1016/0092-8674(92)90478-U  0.59
1992 Ylikomi T, Bocquel MT, Berry M, Gronemeyer H, Chambon P. Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors. The Embo Journal. 11: 3681-3694. DOI: 10.1002/J.1460-2075.1992.Tb05453.X  0.323
1992 White J, Brou C, Wu J, Lutz Y, Moncollin V, Chambon P. The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes. The Embo Journal. 11: 2229-2240. DOI: 10.1002/J.1460-2075.1992.Tb05282.X  0.346
1992 Kastner P, Perez A, Lutz Y, Rochette-Egly C, Gaub MP, Durand B, Lanotte M, Berger R, Chambon P. Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins. The Embo Journal. 11: 629-642. DOI: 10.1002/J.1460-2075.1992.Tb05095.X  0.366
1991 Clifford JL, Petkovich M, Chambon P, Lotan R. Modulation by retinoids of mRNA levels for nuclear retinoic acid receptors in murine melanoma cells. Molecular Endocrinology (Baltimore, Md.). 4: 1546-55. PMID 2178220 DOI: 10.1210/Mend-4-10-1546  0.326
1991 Rio MC, Chenard MP, Wolf C, Marcellin L, Tomasetto C, Lathe R, Bellocq JP, Chambon P. Induction of pS2 and hSP genes as markers of mucosal ulceration of the digestive tract. Gastroenterology. 100: 375-9. PMID 1985035 DOI: 10.1016/0016-5085(91)90205-Y  0.36
1991 Gronemeyer H, Meyer ME, Bocquel MT, Kastner P, Turcotte B, Chambon P. Progestin receptors: isoforms and antihormone action. The Journal of Steroid Biochemistry and Molecular Biology. 40: 271-8. PMID 1958531 DOI: 10.1016/0960-0760(91)90192-8  0.372
1991 Hareuveni M, Wreschner DH, Kieny MP, Dott K, Gautier C, Tomasetto C, Keydar I, Chambon P, Lathe R. Vaccinia recombinants expressing secreted and transmembrane forms of breast cancer-associated epithelial tumour antigen (ETA). Vaccine. 9: 618-26. PMID 1950095 DOI: 10.1016/0264-410X(91)90185-9  0.307
1991 White JH, Brou C, Wu J, Burton N, Egly J-, Chambon P. Evidence for a factor required for transcriptional stimulation by the chimeric acidic activator GAL-VP16 in HeLa cell extracts. Proceedings of the National Academy of Sciences of the United States of America. 88: 7674-7678. PMID 1881909 DOI: 10.1073/Pnas.88.17.7674  0.323
1991 Xiao JH, Davidson I, Matthes H, Garnier JM, Chambon P. Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1 Cell. 65: 551-568. PMID 1851669 DOI: 10.1016/0092-8674(91)90088-G  0.377
1991 Migliaccio A, Castoria G, Falco Ad, Domenico MD, Galdiero M, Nola E, Chambon P, Auricchio F. In vitro phosphorylation and hormone binding activation of the synthetic wild type human estradiol receptor The Journal of Steroid Biochemistry and Molecular Biology. 38: 407-413. PMID 1851630 DOI: 10.1016/0960-0760(91)90328-3  0.312
1991 Elder JT, Fisher GJ, Zhang QY, Eisen D, Krust A, Kastner P, Chambon P, Voorhees JJ. Retinoic Acid Receptor Gene Expression in Human Skin Journal of Investigative Dermatology. 96: 425-433. PMID 1848877 DOI: 10.1111/1523-1747.Ep12469889  0.365
1991 Theisinger B, Welter C, Seitz G, Rio MC, Lathe R, Chambon P, Blin N. Expression of the breast cancer associated gene pS2 and the pancreatic spasmolytic polypeptide gene (hSP) in diffuse type of stomach carcinoma. European Journal of Cancer (Oxford, England : 1990). 27: 770-3. PMID 1829922 DOI: 10.1016/0277-5379(91)90186-H  0.317
1991 Lufkin T, Dierich A, LeMeur M, Mark M, Chambon P. Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression Cell. 66: 1105-1119. PMID 1680563 DOI: 10.1016/0092-8674(91)90034-V  0.368
1991 Nervi C, Vollberg TM, George MD, Zelent A, Chambon P, Jetten AM. Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cells. Experimental Cell Research. 195: 163-170. PMID 1675998 DOI: 10.1016/0014-4827(91)90512-S  0.36
1991 Leroy P, Nakshatri H, Chambon P. Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element Proceedings of the National Academy of Sciences of the United States of America. 88: 10138-10142. PMID 1658797 DOI: 10.1073/Pnas.88.22.10138  0.322
1991 Kruyt FAE, Brink CEvd, Defize LHK, Donath M, Kastner P, Kruijer W, Chambon P, Saag PTvd. Transcriptional regulation of retinoic acid receptor β in retinoic acid-sensitive and -resistant P19 embryocarcinoma cells Mechanisms of Development. 33: 171-178. PMID 1650576 DOI: 10.1016/0925-4773(91)90025-2  0.391
1991 Vasios G, Mader S, Gold JD, Leid M, Lutz Y, Gaub MP, Chambon P, Gudas L. The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element. The Embo Journal. 10: 1149-1158. DOI: 10.1002/J.1460-2075.1991.Tb08055.X  0.566
1991 Zelent A, Mendelsohn C, Kastner P, Krust A, Garnier JM, Ruffenach F, Leroy P, Chambon P. Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing. The Embo Journal. 10: 71-81. DOI: 10.1002/J.1460-2075.1991.Tb07922.X  0.309
1991 Leroy P, Krust A, Zelent A, Mendelsohn C, Garnier JM, Kastner P, Dierich A, Chambon P. Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid. The Embo Journal. 10: 59-69. DOI: 10.1002/J.1460-2075.1991.Tb07921.X  0.31
1991 Smith WC, Nakshatri H, Leroy P, Rees J, Chambon P. A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter. The Embo Journal. 10: 2223-2230. DOI: 10.1002/J.1460-2075.1991.Tb07758.X  0.381
1990 Zheng XM, Black D, Chambon P, Egly JM. Sequencing and expression of complementary DNA for the general transcription factor BTF3. Nature. 344: 556-559. PMID 2320128 DOI: 10.1038/344556A0  0.328
1990 Wright NA, Poulsom R, Stamp GWH, Hall PA, Jeffery RE, Longcroft JM, Rio M, Tomasetto C, Chambon P. Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues. The Journal of Pathology. 162: 279-284. PMID 2290113 DOI: 10.1002/Path.1711620402  0.331
1990 Mukherjee R, Chambon P. A single-stranded DNA-binding protein promotes the binding of the purified oestrogen receptor to its responsive element. Nucleic Acids Research. 18: 5713-5716. PMID 2216763 DOI: 10.1093/Nar/18.19.5713  0.333
1990 Tasset D, Tora L, Fromental C, Scheer E, Chambon P. Distinct classes of transcriptional activating domains function by different mechanisms. Cell. 62: 1177-1187. PMID 2205398 DOI: 10.1016/0092-8674(90)90394-T  0.35
1990 Brand NJ, Petkovich M, Chambon P. Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-α) Nucleic Acids Research. 18: 6799-6806. PMID 2175878 DOI: 10.1093/Nar/18.23.6799  0.367
1990 Åström A, Pettersson U, Krust A, Chambon P, Voorhees JJ. Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription Biochemical and Biophysical Research Communications. 173: 339-345. PMID 2175182 DOI: 10.1016/S0006-291X(05)81062-9  0.311
1990 Kastner P, Krust A, Mendelsohn C, Garnier JM, Zelent A, Leroy P, Staub A, Chambon P. Murine isoforms of retinoic acid receptor gamma with specific patterns of expression. Proceedings of the National Academy of Sciences of the United States of America. 87: 2700-2704. PMID 2157210 DOI: 10.1073/Pnas.87.7.2700  0.356
1990 Rochette-Egly C, Fromental C, Chambon P. General repression of enhanson activity by the adenovirus-2 E1A proteins. Genes & Development. 4: 137-150. PMID 2155159 DOI: 10.1101/Gad.4.1.137  0.404
1990 Gaub M, Bellard M, Scheuer I, Chambon P, Sassone-Corsi P. Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex. Cell. 63: 1267-1276. PMID 2124518 DOI: 10.1016/0092-8674(90)90422-B  0.347
1990 Basset P, Bellocq JP, Wolf C, Stoll I, Hutin P, Limacher JM, Podhajcer OL, Chenard MP, Rio MC, Chambon P. A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas Nature. 348: 699-704. PMID 1701851 DOI: 10.1038/348699A0  0.308
1990 Turcotte B, Meyer ME, Bocquel MT, Bélanger L, Chambon P. Repression of the alpha-fetoprotein gene promoter by progesterone and chimeric receptors in the presence of hormones and antihormones. Molecular and Cellular Biology. 10: 5002-6. PMID 1697036 DOI: 10.1128/Mcb.10.9.5002  0.372
1990 Kastner P, Krust A, Turcotte B, Stropp U, Tora L, Gronemeyer H, Chambon P. Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. The Embo Journal. 9: 1603-1614. DOI: 10.1002/J.1460-2075.1990.Tb08280.X  0.405
1990 Nicholson RC, Mader S, Nagpal S, Leid M, Rochette-Egly C, Chambon P. Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site. The Embo Journal. 9: 4443-4454. DOI: 10.1002/J.1460-2075.1990.Tb07895.X  0.608
1990 Meyer M-, Pornon A, Ji J, Bocquel MT, Chambon P, Gronemeyer H. Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor. The Embo Journal. 9: 3923-3932. DOI: 10.1002/J.1460-2075.1990.Tb07613.X  0.377
1990 Berry M, Metzger D, Chambon P. Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. The Embo Journal. 9: 2811-2818. DOI: 10.1002/J.1460-2075.1990.Tb07469.X  0.378
1990 Ponglikitmongkol M, White JH, Chambon P. Synergistic activation of transcription by the human estrogen receptor bound to tandem responsive elements. The Embo Journal. 9: 2221-2231. DOI: 10.1002/J.1460-2075.1990.Tb07392.X  0.345
1989 Mader S, Kumar V, Verneuil Hd, Chambon P. Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element. Nature. 338: 271-274. PMID 2922054 DOI: 10.1038/338271A0  0.606
1989 Berry M, Nunez AM, Chambon P. Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence. Proceedings of the National Academy of Sciences of the United States of America. 86: 1218-22. PMID 2919170 DOI: 10.1073/Pnas.86.4.1218  0.369
1989 Migliaccio A, Domenico MD, Green S, Falco Ad, Kajtaniak EL, Blasi F, Chambon P, Auricchio F. Phosphorylation on tyrosine of in vitro synthesized human estrogen receptor activates its hormone binding. Molecular Endocrinology. 3: 1061-1069. PMID 2797002 DOI: 10.1210/Mend-3-7-1061  0.343
1989 Meyer M, Gronemeyer H, Turcotte B, Bocquel M, Tasset D, Chambon P. Steroid hormone receptors compete for factors that mediate their enhancer function Cell. 57: 433-442. PMID 2720778 DOI: 10.1016/0092-8674(89)90918-5  0.387
1989 Bocquel MT, Kumar V, Stricker C, Chambon P, Gronemeyer H. The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific. Nucleic Acids Research. 17: 2581-95. PMID 2717402 DOI: 10.1093/Nar/17.7.2581  0.412
1989 Cavallini B, Faus I, Matthes H, Chipoulet JM, Winsor B, Egly JM, Chambon P. Cloning of the gene encoding the yeast protein BTF1Y, which can substitute for the human TATA box-binding factor. Proceedings of the National Academy of Sciences of the United States of America. 86: 9803-9807. PMID 2690073 DOI: 10.1073/Pnas.86.24.9803  0.377
1989 Luqmani Y, Bennett C, Paterson I, Corbishley CM, Rio M, Chambon P, Ryall G. Expression of the pS2 gene in normal, benign and neoplastic human stomach. International Journal of Cancer. 44: 806-812. PMID 2583860 DOI: 10.1002/Ijc.2910440510  0.359
1989 Vasios GW, Gold JD, Petkovich M, Chambon P, Gudas LJ. A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene Proceedings of the National Academy of Sciences of the United States of America. 86: 9099-9103. PMID 2556699 DOI: 10.1073/Pnas.86.23.9099  0.377
1989 Dollé P, Ruberte E, Kastner P, Petkovich M, Stoner CM, Gudas LJ, Chambon P. Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse Nature. 342: 702-705. PMID 2556642 DOI: 10.1038/342702A0  0.647
1989 Ragsdale CW, Petkovich M, Gates PB, Chambon P, Brockes JP. Identification of a novel retinoic acid receptor in regenerative tissues of the newt. Nature. 341: 654-7. PMID 2552324 DOI: 10.1038/341654A0  0.385
1989 Hashimoto Y, Petkovich M, Gaub MP, Kagechika H, Shudo K, Chambon P. The retinoic acid receptors alpha and beta are expressed in the human promyelocytic leukemia cell line HL-60. Molecular Endocrinology (Baltimore, Md.). 3: 1046-52. PMID 2552297 DOI: 10.1210/Mend-3-7-1046  0.317
1989 Lennard AC, Matthes HWD, Egly JM, Chambon P. Stereospecific relationships between elements in an SV40/Adenovirus-2 heterologous promoter Nucleic Acids Research. 17: 6903-6914. PMID 2550902 DOI: 10.1093/Nar/17.17.6903  0.302
1989 Krust A, Kastner P, Petkovich M, Zelent A, Chambon P. A third human retinoic acid receptor, hRAR-gamma. Proceedings of the National Academy of Sciences of the United States of America. 86: 5310-4. PMID 2546152 DOI: 10.1073/Pnas.86.14.5310  0.362
1989 Zelent A, Krust A, Petkovich M, Kastner P, Chambon P. Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin. Nature. 339: 714-7. PMID 2544807 DOI: 10.1038/339714A0  0.343
1989 Gaub MP, Lutz Y, Ruberte E, Petkovich M, Brand N, Chambon P. Antibodies specific to the retinoic acid human nuclear receptors alpha and beta. Proceedings of the National Academy of Sciences of the United States of America. 86: 3089-93. PMID 2541430 DOI: 10.1073/Pnas.86.9.3089  0.316
1989 Tomasetto C, Wolf C, Rio MC, Mehtali M, LeMeur M, Gerlinger P, Chambon P, Lathe R. Breast cancer protein PS2 synthesis in mammary gland of transgenic mice and secretion into milk. Molecular Endocrinology (Baltimore, Md.). 3: 1579-84. PMID 2481815 DOI: 10.1210/Mend-3-10-1579  0.363
1989 Noji S, Koyama E, Yamaai T, Nohno T, Petkovich M, Chambon P, Taniguchi S. Developmental expression of the retinoic acid receptor genes, as revealed by hybridization Cell Differentiation and Development. 27: 169. DOI: 10.1016/0922-3371(89)90519-4  0.378
1989 Macchi M, Bornert JM, Davidson I, Kanno M, Rosales R, Vigneron M, Xiao JH, Fromental C, Chambon P. The SV40 TC-II(kappa B) enhanson binds ubiquitous and cell type specifically inducible nuclear proteins from lymphoid and non-lymphoid cell lines. The Embo Journal. 8: 4215-4227. DOI: 10.1002/J.1460-2075.1989.Tb08607.X  0.304
1989 Kanno M, Fromental C, Staub A, Ruffenach F, Davidson I, Chambon P. The SV40 TC-II(kappa B) and the related H-2Kb enhansons exhibit different cell type specific and inducible proto-enhancer activities, but the SV40 core sequence and the AP-2 binding site have no enhanson properties. The Embo Journal. 8: 4205-4214. DOI: 10.1002/J.1460-2075.1989.Tb08606.X  0.328
1989 Tora L, Mullick A, Metzger D, Ponglikitmongkol M, Park I, Chambon P. The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties. The Embo Journal. 8: 1981-1986. DOI: 10.1002/J.1460-2075.1989.Tb03604.X  0.335
1989 Webster NJ, Green S, Tasset D, Ponglikitmongkol M, Chambon P. The transcriptional activation function located in the hormone-binding domain of the human oestrogen receptor is not encoded in a single exon. The Embo Journal. 8: 1441-1446. DOI: 10.1002/J.1460-2075.1989.Tb03526.X  0.374
1989 Nunez AM, Berry M, Imler JL, Chambon P. The 5' flanking region of the pS2 gene contains a complex enhancer region responsive to oestrogens, epidermal growth factor, a tumour promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein. The Embo Journal. 8: 823-829. DOI: 10.1002/J.1460-2075.1989.Tb03443.X  0.35
1989 Eul J, Meyer ME, Tora L, Bocquel MT, Quirin-Stricker C, Chambon P, Gronemeyer H. Expression of active hormone and DNA-binding domains of the chicken progesterone receptor in E. coli. The Embo Journal. 8: 83-90. DOI: 10.1002/J.1460-2075.1989.Tb03351.X  0.362
1988 Webster NJ, Green S, Jin JR, Chambon P. The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell. 54: 199-207. PMID 3390864 DOI: 10.1016/0092-8674(88)90552-1  0.37
1988 Cavallini B, Huet J, Plassat JL, Sentenac A, Egly JM, Chambon P. A yeast activity can substitute for the HeLa cell TATA box factor. Nature. 334: 77-80. PMID 3290688 DOI: 10.1038/334077A0  0.349
1988 Metzger D, White JH, Chambon P. The human oestrogen receptor functions in yeast Nature. 334: 31-36. PMID 3290686 DOI: 10.1038/334031A0  0.367
1988 Saceda M, Lippman ME, Chambon P, Lindsey RL, Ponglikitmongkol M, Puente M, Martin MB. Regulation of the estrogen receptor in MCF-7 cells by estradiol Molecular Endocrinology. 2: 1157-1162. PMID 3216858 DOI: 10.1210/Mend-2-12-1157  0.343
1988 Kumar V, Chambon P. The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer. Cell. 55: 145-156. PMID 3167974 DOI: 10.1016/0092-8674(88)90017-7  0.316
1988 White JH, Metzger D, Chambon P. Expression and function of the human estrogen receptor in yeast. Cold Spring Harbor Symposia On Quantitative Biology. 53: 819-828. PMID 3076099 DOI: 10.1101/Sqb.1988.053.01.093  0.331
1988 Rio MC, Bellocq JP, Daniel JY, Tomasetto C, Lathe R, Chenard MP, Batzenschlager A, Chambon P. Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. Science (New York, N.Y.). 241: 705-8. PMID 3041593 DOI: 10.1126/Science.3041593  0.359
1988 Green S, Chambon P. Nuclear receptors enhance our understanding of transcription regulation Trends in Genetics. 4: 309-314. PMID 2853466 DOI: 10.1016/0168-9525(88)90108-4  0.37
1988 Fromental C, Kanno M, Nomiyama H, Chambon P. Cooperativity and hierarchical levels of functional organization in the SV40 enhancer Cell. 54: 943-953. PMID 2843294 DOI: 10.1016/0092-8674(88)90109-2  0.343
1988 Davidson I, Xiao JH, Rosales R, Staub A, Chambon P. The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence. Cell. 54: 931-942. PMID 2843293 DOI: 10.1016/0092-8674(88)90108-0  0.305
1988 Tora L, Gronemeyer H, Turcotte B, Gaub M, Chambon P. The N-terminal region of the chicken progesterone receptor specifies target gene activation. Nature. 333: 185-188. PMID 2835683 DOI: 10.1038/333185A0  0.391
1988 Brand N, Petkovich M, Krust A, Chambon P, de Thé H, Marchio A, Tiollais P, Dejean A. Identification of a second human retinoic acid receptor. Nature. 332: 850-3. PMID 2833708 DOI: 10.1038/332850A0  0.386
1988 Webster N, Jin JR, Green S, Hollis M, Chambon P. The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator. Cell. 52: 169-78. PMID 2830022 DOI: 10.1016/0092-8674(88)90505-3  0.381
1988 Tora L, Gaub MP, Mader S, Dierich A, Bellard M, Chambon P. Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter. The Embo Journal. 7: 3771-3778. DOI: 10.1002/J.1460-2075.1988.Tb03261.X  0.612
1988 Ponglikitmongkol M, Green S, Chambon P. Genomic organization of the human oestrogen receptor gene. The Embo Journal. 7: 3385-3388. DOI: 10.1002/J.1460-2075.1988.Tb03211.X  0.388
1988 Green S, Kumar V, Theulaz I, Wahli W, Chambon P. The N-terminal DNA-binding 'zinc finger' of the oestrogen and glucocorticoid receptors determines target gene specificity. The Embo Journal. 7: 3037-3044. DOI: 10.1002/J.1460-2075.1988.Tb03168.X  0.378
1988 Theulaz I, Hipskind R, Heggeler-Bordier Bt, Green S, Kumar V, Chambon P, Wahli W. Expression of human estrogen receptor mutants in Xenopus oocytes: correlation between transcriptional activity and ability to form protein-DNA complexes. The Embo Journal. 7: 1653-1660. DOI: 10.1002/J.1460-2075.1988.Tb02992.X  0.418
1987 Jeltsch JM, Roberts M, Schatz C, Garnier JM, Brown AM, Chambon P. Structure of the human oestrogen-responsive gene pS2. Nucleic Acids Research. 15: 1401-14. PMID 3822834 DOI: 10.1093/Nar/15.4.1401  0.353
1987 Kumar V, Green S, Stack G, Berry M, Jin J, Chambon P. Functional domains of the human estrogen receptor. Cell. 51: 941-951. PMID 3690665 DOI: 10.1016/0092-8674(87)90581-2  0.38
1987 Schaeffer E, Lucero MA, Jeltsch JM, Py MC, Levin MJ, Chambon P, Cohen GN, Zakin MM. Complete structure of the human transferrin gene. Comparison with analogous chicken gene and human pseudogene. Gene. 56: 109-16. PMID 3678832 DOI: 10.1016/0378-1119(87)90163-6  0.302
1987 Nunez AM, Jakowlev S, Briand JP, Gaire M, Krust A, Rio MC, Chambon P. Characterization of the estrogen-induced pS2 protein secreted by the human breast cancer cell line MCF-7. Endocrinology. 121: 1759-65. PMID 3665845 DOI: 10.1210/Endo-121-5-1759  0.313
1987 Zheng X, Moncollin V, Egly J, Chambon P. A General Transcription Factor Forms a Stable Complex With RNA Polymerase B (II) Cell. 50: 361-368. PMID 3607874 DOI: 10.1016/0092-8674(87)90490-9  0.304
1987 Rio MC, Bellocq JP, Gairard B, Rasmussen UB, Krust A, Koehl C, Calderoli H, Schiff V, Renaud R, Chambon P. Specific expression of the pS2 gene in subclasses of breast cancers in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2. Proceedings of the National Academy of Sciences of the United States of America. 84: 9243-9247. PMID 3321071 DOI: 10.1073/Pnas.84.24.9243  0.334
1987 Green S, Chambon P. Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor. Nature. 325: 75-78. PMID 3025750 DOI: 10.1038/325075A0  0.423
1987 Matthes HWD, Staub A, Chambon P. [14] The segmented paper method: DNA synthesis and mutagenesis by rapid microscale “shotgun gene synthesis” Methods in Enzymology. 154: 249-287. PMID 2828854 DOI: 10.1016/0076-6879(87)54080-0  0.34
1987 Xiao JH, Davidson I, Macchi M, Rosales R, Vigneron M, Staub A, Chambon P. In vitro binding of several cell-specific and ubiquitous nuclear proteins to the GT-I motif of the SV40 enhancer. Genes & Development. 1: 794-807. PMID 2828172 DOI: 10.1101/Gad.1.8.794  0.334
1987 Nomiyama H, Fromental C, Xiao JH, Chambon P. Cell-specific activity of the constituent elements of the simian virus 40 enhancer. Proceedings of the National Academy of Sciences of the United States of America. 84: 7881-7885. PMID 2825168 DOI: 10.1073/Pnas.84.22.7881  0.349
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