Frank Longo - Publications

Affiliations: 
Stanford University, Palo Alto, CA 

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mufson EJ, Counts SE, Ginsberg SD, Mahady L, Perez SE, Massa SM, Longo FM, Ikonomovic MD. Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease. Frontiers in Neuroscience. 13: 533. PMID 31312116 DOI: 10.3389/fnins.2019.00533  0.44
2019 Simmons DA, Lartey FM, Schüler E, Rafat M, King G, Kim A, Ko R, Semaan S, Gonzalez S, Jenkins M, Pradhan P, Shih Z, Wang J, von Eyben R, Graves EE, ... ... Longo FM, et al. Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 31253467 DOI: 10.1016/j.radonc.2019.06.006  0.44
2019 Xie Y, Meeker RB, Massa SM, Longo FM. Modulation of the p75 neurotrophin receptor suppresses age-related basal forebrain cholinergic neuron degeneration. Scientific Reports. 9: 5273. PMID 30918278 DOI: 10.1038/s41598-019-41654-8  0.44
2018 Simmons DA, James ML, Belichenko NP, Semaan S, Condon C, Kuan J, Shuhendler AJ, Miao Z, Chin FT, Longo FM. TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31. Human Molecular Genetics. PMID 29860333 DOI: 10.1093/hmg/ddy202  0.44
2016 Simmons DA, Belichenko NP, Ford EC, Semaan S, Monbureau M, Aiyaswamy S, Holman CM, Condon C, Shamloo M, Massa SM, Longo FM. A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics. 25: 4920-4938. PMID 28171570 DOI: 10.1093/hmg/ddw316  0.44
2016 Simmons DA, Longo FM, Massa SM. Neurotrophin receptor signaling as a therapeutic target for Huntington's Disease. Cns & Neurological Disorders Drug Targets. PMID 27823570  0.44
2016 Darcq E, Morisot N, Phamluong K, Warnault V, Jeanblanc J, Longo FM, Massa SM, Ron D. The Neurotrophic Factor Receptor p75 in the Rat Dorsolateral Striatum Drives Excessive Alcohol Drinking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 10116-27. PMID 27683907 DOI: 10.1523/JNEUROSCI.4597-14.2016  0.44
2016 Simmons DA, Belichenko NP, Ford EC, Semaan S, Monbureau M, Aiyaswamy S, Holman CM, Condon C, Shamloo M, Massa SM, Longo FM. A small molecule p75NTR ligand normalizes signaling and reduces Huntington's Disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics. PMID 27638888 DOI: 10.1093/hmg/ddw316  0.44
2016 Yang T, Massa SM, Tran KC, Simmons DA, Rajadas J, Zeng AY, Jang T, Carsanaro S, Longo FM. A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth. Neuropharmacology. PMID 27334657 DOI: 10.1016/j.neuropharm.2016.06.015  0.44
2015 Warnault V, Darcq E, Morisot N, Phamluong K, Wilbrecht L, Massa SM, Longo FM, Ron D. The BDNF Valine 68 to Methionine Polymorphism Increases Compulsive Alcohol Drinking in Mice that Is Reversed by Tropomyosin Receptor Kinase B Activation. Biological Psychiatry. PMID 26204799 DOI: 10.1016/j.biopsych.2015.06.007  0.44
2014 Friesland A, Weng Z, Duenas M, Massa SM, Longo FM, Lu Q. Amelioration of cisplatin-induced experimental peripheral neuropathy by a small molecule targeting p75 NTR. Neurotoxicology. 45: 81-90. PMID 25277379 DOI: 10.1016/j.neuro.2014.09.005  0.44
2014 Simmons DA, Knowles JK, Belichenko NP, Banerjee G, Finkle C, Massa SM, Longo FM. A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression. Plos One. 9: e102136. PMID 25153701 DOI: 10.1371/journal.pone.0102136  0.44
2014 Nguyen TV, Shen L, Vander Griend L, Quach LN, Belichenko NP, Saw N, Yang T, Shamloo M, Wyss-Coray T, Massa SM, Longo FM. Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice. Journal of Alzheimer's Disease : Jad. 42: 459-83. PMID 24898660 DOI: 10.3233/JAD-140036  0.44
2014 Villeda SA, Plambeck KE, Middeldorp J, Castellano JM, Mosher KI, Luo J, Smith LK, Bieri G, Lin K, Berdnik D, Wabl R, Udeochu J, Wheatley EG, Zou B, Simmons DA, ... ... Longo FM, et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nature Medicine. 20: 659-63. PMID 24793238 DOI: 10.1038/nm.3569  0.44
2013 Simmons DA, Belichenko NP, Yang T, Condon C, Monbureau M, Shamloo M, Jing D, Massa SM, Longo FM. A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18712-27. PMID 24285878 DOI: 10.1523/JNEUROSCI.1310-13.2013  0.44
2013 Longo FM, Massa SM. Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease. Nature Reviews. Drug Discovery. 12: 507-25. PMID 23977697 DOI: 10.1038/nrd4024  0.44
2013 Shi J, Longo FM, Massa SM. A small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injury. Stem Cells (Dayton, Ohio). 31: 2561-74. PMID 23940017 DOI: 10.1002/stem.1516  0.44
2013 Knowles JK, Simmons DA, Nguyen TV, Vander Griend L, Xie Y, Zhang H, Yang T, Pollak J, Chang T, Arancio O, Buckwalter MS, Wyss-Coray T, Massa SM, Longo FM. Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model. Neurobiology of Aging. 34: 2052-63. PMID 23545424 DOI: 10.1016/j.neurobiolaging.2013.02.015  0.44
2013 Tep C, Lim TH, Ko PO, Getahun S, Ryu JC, Goettl VM, Massa SM, Basso M, Longo FM, Yoon SO. Oral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 397-410. PMID 23303920 DOI: 10.1523/JNEUROSCI.0399-12.2013  0.44
2012 Han J, Pollak J, Yang T, Siddiqui MR, Doyle KP, Taravosh-Lahn K, Cekanaviciute E, Han A, Goodman JZ, Jones B, Jing D, Massa SM, Longo FM, Buckwalter MS. Delayed administration of a small molecule tropomyosin-related kinase B ligand promotes recovery after hypoxic-ischemic stroke. Stroke; a Journal of Cerebral Circulation. 43: 1918-24. PMID 22535263 DOI: 10.1161/STROKEAHA.111.641878  0.44
2012 Schmid DA, Yang T, Ogier M, Adams I, Mirakhur Y, Wang Q, Massa SM, Longo FM, Katz DM. A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1803-10. PMID 22302819 DOI: 10.1523/JNEUROSCI.0865-11.2012  0.44
2010 Massa SM, Yang T, Xie Y, Shi J, Bilgen M, Joyce JN, Nehama D, Rajadas J, Longo FM. Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. The Journal of Clinical Investigation. 120: 1774-85. PMID 20407211 DOI: 10.1172/JCI41356  0.44
2009 Knowles JK, Rajadas J, Nguyen TV, Yang T, LeMieux MC, Vander Griend L, Ishikawa C, Massa SM, Wyss-Coray T, Longo FM. The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10627-37. PMID 19710315 DOI: 10.1523/JNEUROSCI.0620-09.2009  0.44
2009 Lu Q, Longo FM, Zhou H, Massa SM, Chen YH. Signaling through Rho GTPase pathway as viable drug target. Current Medicinal Chemistry. 16: 1355-65. PMID 19355891 DOI: 10.2174/092986709787846569  0.44
2008 Yang T, Knowles JK, Lu Q, Zhang H, Arancio O, Moore LA, Chang T, Wang Q, Andreasson K, Rajadas J, Fuller GG, Xie Y, Massa SM, Longo FM. Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment. Plos One. 3: e3604. PMID 18978948 DOI: 10.1371/journal.pone.0003604  0.44
2008 James SE, Burden H, Burgess R, Xie Y, Yang T, Massa SM, Longo FM, Lu Q. Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants. Neurotoxicology. 29: 605-12. PMID 18539332 DOI: 10.1016/j.neuro.2008.04.008  0.44
2008 Longo FM, Massa SM. Small molecule modulation of p75 neurotrophin receptor functions. Cns & Neurological Disorders Drug Targets. 7: 63-70. PMID 18289033 DOI: 10.2174/187152708783885093  0.44
2007 Longo FM, Yang T, Knowles JK, Xie Y, Moore LA, Massa SM. Small molecule neurotrophin receptor ligands: novel strategies for targeting Alzheimer's disease mechanisms. Current Alzheimer Research. 4: 503-6. PMID 18220511 DOI: 10.2174/156720507783018316  0.44
2006 Yang T, Massa SM, Longo FM. LAR protein tyrosine phosphatase receptor associates with TrkB and modulates neurotrophic signaling pathways. Journal of Neurobiology. 66: 1420-36. PMID 17013927 DOI: 10.1002/neu.20291  0.44
2006 Pehar M, Cassina P, Vargas MR, Xie Y, Beckman JS, Massa SM, Longo FM, Barbeito L. Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain. The European Journal of Neuroscience. 24: 1575-80. PMID 17004921 DOI: 10.1111/j.1460-9568.2006.05040.x  0.44
2006 Massa SM, Xie Y, Yang T, Harrington AW, Kim ML, Yoon SO, Kraemer R, Moore LA, Hempstead BL, Longo FM. Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5288-300. PMID 16707781 DOI: 10.1523/JNEUROSCI.3547-05.2006  0.44
2006 Xie Y, Massa SM, Ensslen-Craig SE, Major DL, Yang T, Tisi MA, Derevyanny VD, Runge WO, Mehta BP, Moore LA, Brady-Kalnay SM, Longo FM. Protein-tyrosine phosphatase (PTP) wedge domain peptides: a novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase function. The Journal of Biological Chemistry. 281: 16482-92. PMID 16613844 DOI: 10.1074/jbc.M603131200  0.44
2006 Longo FM, Yang T, Xie Y, Massa SM. Small molecule approaches for promoting neurogenesis. Current Alzheimer Research. 3: 5-10. PMID 16472196 DOI: 10.2174/156720506775697089  0.44
2005 Longo FM, Massa SM. Neurotrophin receptor-based strategies for Alzheimer's disease. Current Alzheimer Research. 2: 167-9. PMID 15974914 DOI: 10.2174/1567205053585819  0.44
2004 Longo FM, Massa SM. Neuroprotective strategies in Alzheimer's disease. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 1: 117-27. PMID 15717012 DOI: 10.1602/neurorx.1.1.117  0.44
2004 Longo FM, Massa SM. Neurotrophin-based strategies for neuroprotection. Journal of Alzheimer's Disease : Jad. 6: S13-7. PMID 15665408  0.44
2003 Massa SM, Xie Y, Longo FM. Alzheimer's therapeutics: neurotrophin domain small molecule mimetics. Journal of Molecular Neuroscience : Mn. 20: 323-6. PMID 14501015 DOI: 10.1385/JMN:20:3:323  0.44
2003 Zhang C, Xie Y, Martignetti JA, Yeo TT, Massa SM, Longo FM. A candidate chimeric mammalian mRNA transcript is derived from distinct chromosomes and is associated with nonconsensus splice junction motifs. Dna and Cell Biology. 22: 303-15. PMID 12941158 DOI: 10.1089/104454903322216653  0.44
2003 Yang T, Bernabeu R, Xie Y, Zhang JS, Massa SM, Rempel HC, Longo FM. Leukocyte antigen-related protein tyrosine phosphatase receptor: a small ectodomain isoform functions as a homophilic ligand and promotes neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3353-63. PMID 12716943  0.44
2002 Massa SM, Xie Y, Longo FM. Alzheimer's therapeutics: neurotrophin small molecule mimetics. Journal of Molecular Neuroscience : Mn. 19: 107-11. PMID 12212765 DOI: 10.1007/s12031-002-0019-1  0.44
2001 Xie Y, Yeo TT, Zhang C, Yang T, Tisi MA, Massa SM, Longo FM. The leukocyte common antigen-related protein tyrosine phosphatase receptor regulates regenerative neurite outgrowth in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5130-8. PMID 11438588  0.44
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