Shannon D. Shields - Publications

Affiliations: 
Neuroscience Genentech, Inc., San Francisco, CA, United States 
Area:
Pain

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Deng L, Dourado M, Reese RM, Huang K, Shields SD, Stark KL, Maksymetz J, Lin H, Kaminker JS, Jung M, Foreman O, Tao J, Ngu H, Joseph V, Roose-Girma M, et al. Nav1.7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids. Neuron. PMID 37352856 DOI: 10.1016/j.neuron.2023.05.024  0.364
2020 Reese RM, Dourado M, Anderson K, Warming S, Stark KL, Balestrini A, Suto E, Lee W, Riol-Blanco L, Shields SD, Hackos DH. Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma. Scientific Reports. 10: 979. PMID 31969645 DOI: 10.1038/s41598-020-57936-5  0.304
2018 Shields SD, Deng L, Reese RM, Dourado M, Tao J, Foreman O, Chang JH, Hackos DH. Insensitivity to pain upon adult-onset deletion of Na1.7 or its blockade with selective inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30301756 DOI: 10.1523/Jneurosci.1049-18.2018  0.458
2018 Chen H, Volgraf M, Do S, Kolesnikov A, Shore DG, Verma VA, Villemure E, Wang L, Chen Y, Hu B, Lu AJ, Wu G, Xu X, Yuen PW, Zhang Y, ... ... Shields SD, et al. Discovery of a Potent (4R,5S)-4-Fluoro-5-Methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist and its Methylene Phosphate Prodrug Guided By Molecular Modeling. Journal of Medicinal Chemistry. PMID 29590749 DOI: 10.1021/Acs.Jmedchem.8B00117  0.361
2015 Shields SD, Butt RP, Dib-Hajj SD, Waxman SG. Oral administration of PF-01247324, a subtype-selective Nav1.8 blocker, reverses cerebellar deficits in a mouse model of multiple sclerosis. Plos One. 10: e0119067. PMID 25747279 DOI: 10.1371/Journal.Pone.0119067  0.493
2014 González-Fernández C, Fernández-Martos CM, Shields SD, Arenas E, Javier Rodríguez F. Wnts are expressed in the spinal cord of adult mice and are differentially induced after injury. Journal of Neurotrauma. 31: 565-81. PMID 24367909 DOI: 10.1089/neu.2013.3067  0.308
2012 Shields SD, Cheng X, Uçeyler N, Sommer C, Dib-Hajj SD, Waxman SG. Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10819-32. PMID 22875917 DOI: 10.1523/Jneurosci.0304-12.2012  0.585
2012 Shields SD, Ahn HS, Yang Y, Han C, Seal RP, Wood JN, Waxman SG, Dib-Hajj SD. Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system. Pain. 153: 2017-30. PMID 22703890 DOI: 10.1016/J.Pain.2012.04.022  0.62
2012 Shields SD, Cheng X, Gasser A, Saab CY, Tyrrell L, Eastman EM, Iwata M, Zwinger PJ, Black JA, Dib-Hajj SD, Waxman SG. A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis. Annals of Neurology. 71: 186-94. PMID 22367990 DOI: 10.1002/Ana.22665  0.512
2011 Shields SD, Waxman SG. Cerebellar dysfunction in multiple sclerosis: in the blink of an eye. Multiple Sclerosis (Houndmills, Basingstoke, England). 17: 1152-4. PMID 21980147 DOI: 10.1177/1352458511410345  0.355
2011 Shields SD. Intracellular pH in primary somatosensory neurons. Neuroscience Letters. 501: 1-3. PMID 21763397 DOI: 10.1016/J.Neulet.2011.06.046  0.36
2010 Shields SD, Moore KD, Phelps PE, Basbaum AI. Olfactory ensheathing glia express aquaporin 1. The Journal of Comparative Neurology. 518: 4329-41. PMID 20853510 DOI: 10.1002/Cne.22459  0.583
2010 Shields SD, Cavanaugh DJ, Lee H, Anderson DJ, Basbaum AI. Pain behavior in the formalin test persists after ablation of the great majority of C-fiber nociceptors. Pain. 151: 422-9. PMID 20832171 DOI: 10.1016/J.Pain.2010.08.001  0.701
2009 Cavanaugh DJ, Lee H, Lo L, Shields SD, Zylka MJ, Basbaum AI, Anderson DJ. Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proceedings of the National Academy of Sciences of the United States of America. 106: 9075-80. PMID 19451647 DOI: 10.1073/Pnas.0901507106  0.718
2009 Cavanaugh DJ, Lee H, Lo L, Shields SD, Zylka MJ, Basbaum AI, Anderson DJ. Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 22, (9075-9080) DOI: 10.1073/pnas.0901507106) Proceedings of the National Academy of Sciences of the United States of America. 106: 11424. DOI: 10.1073/Pnas.0906213106  0.72
2007 Shields SD, Mazario J, Skinner K, Basbaum AI. Anatomical and functional analysis of aquaporin 1, a water channel in primary afferent neurons. Pain. 131: 8-20. PMID 17257750 DOI: 10.1016/J.Pain.2006.11.018  0.661
2003 Shields SD, Eckert WA, Basbaum AI. Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis. The Journal of Pain : Official Journal of the American Pain Society. 4: 465-70. PMID 14622667 DOI: 10.1067/S1526-5900(03)00781-8  0.576
2001 Chuang HH, Prescott ED, Kong H, Shields S, Jordt SE, Basbaum AI, Chao MV, Julius D. Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature. 411: 957-62. PMID 11418861 DOI: 10.1038/35082088  0.679
2001 Lyeth BG, Gong QZ, Shields S, Muizelaar JP, Berman RF. Group I metabotropic glutamate antagonist reduces acute neuronal degeneration and behavioral deficits after traumatic brain injury in rats. Experimental Neurology. 169: 191-9. PMID 11312571 DOI: 10.1006/Exnr.2001.7643  0.305
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