Year |
Citation |
Score |
2024 |
Rose EP, Osterberg VR, Banga JS, Gorbunova V, Unni VK. Alpha-synuclein regulates the repair of genomic DNA double-strand breaks in a DNA-PK -dependent manner. Biorxiv : the Preprint Server For Biology. PMID 38496612 DOI: 10.1101/2024.02.29.582819 |
0.311 |
|
2022 |
Weston LJ, Bowman AM, Osterberg VR, Meshul CK, Woltjer RL, Unni VK. Aggregated Alpha-Synuclein Inclusions within the Nucleus Predict Impending Neuronal Cell Death in a Mouse Model of Parkinsonism. International Journal of Molecular Sciences. 23. PMID 36499619 DOI: 10.3390/ijms232315294 |
0.348 |
|
2021 |
Dent SE, King DP, Osterberg VR, Adams EK, Mackiewicz MR, Weissman TA, Unni VK. Phosphorylation of the aggregate-forming protein alpha-synuclein on serine-129 inhibits its DNA-bending properties. The Journal of Biological Chemistry. 101552. PMID 34973339 DOI: 10.1016/j.jbc.2021.101552 |
0.69 |
|
2021 |
Weber Boutros S, Raber J, Unni VK. Effects of Alpha-Synuclein Targeted Antisense Oligonucleotides on Lewy Body-Like Pathology and Behavioral Disturbances Induced by Injections of Pre-Formed Fibrils in the Mouse Motor Cortex. Journal of Parkinson's Disease. PMID 34057097 DOI: 10.3233/JPD-212566 |
0.348 |
|
2021 |
Weston LJ, Cook ZT, Stackhouse TL, Sal MK, Schultz B, Tobias ZJC, Osterberg VR, Brockway NL, Pizano S, Glover G, Weissman TA, Unni VK. In vivo aggregation of presynaptic alpha-synuclein is not influenced by its phosphorylation at serine-129. Neurobiology of Disease. 105291. PMID 33556542 DOI: 10.1016/j.nbd.2021.105291 |
0.731 |
|
2021 |
Weston LJ, Stackhouse TL, Spinelli KJ, Boutros SW, Rose EP, Osterberg VR, Luk KC, Raber J, Weissman TA, Unni VK. Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies. The Journal of Biological Chemistry. 100273. PMID 33428941 DOI: 10.1016/j.jbc.2021.100273 |
0.745 |
|
2020 |
Schaser AJ, Stackhouse TL, Weston LJ, Kerstein PC, Osterberg VR, López CS, Dickson DW, Luk KC, Meshul CK, Woltjer RL, Unni VK. Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy. Acta Neuropathologica Communications. 8: 150. PMID 32859276 DOI: 10.1186/S40478-020-01026-0 |
0.497 |
|
2019 |
Schaser AJ, Osterberg VR, Dent SE, Stackhouse TL, Wakeham CM, Boutros SW, Weston LJ, Owen N, Weissman TA, Luna E, Raber J, Luk KC, McCullough AK, Woltjer RL, Unni VK. Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders. Scientific Reports. 9: 10919. PMID 31358782 DOI: 10.1038/S41598-019-47227-Z |
0.741 |
|
2019 |
Brockway NL, Cook ZT, O'Gallagher M, Tobias ZJC, Gedi M, Carey KM, Unni VK, Pan YA, Metz MR, Weissman TA. Multicolor lineage tracing using in vivo time-lapse imaging reveals coordinated death of clonally related cells in the developing vertebrate brain. Developmental Biology. PMID 31102591 DOI: 10.1016/J.Ydbio.2019.05.006 |
0.691 |
|
2019 |
Schaser A, López CS, Unni V. Utilizing Correlated Light and Electron Microscopy to Examine Alpha-Synuclein Pathology in a Mouse Model of Parkinson's Disease Microscopy and Microanalysis. 25: 1132-1133. DOI: 10.1017/S1431927619006391 |
0.388 |
|
2016 |
Volpicelli-Daley LA, Abdelmotilib H, Liu Z, Stoyka L, Daher JP, Milnerwood AJ, Unni VK, Hirst WD, Yue Z, Zhao HT, Fraser K, Kennedy RE, West AB. G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7415-27. PMID 27413152 DOI: 10.1523/Jneurosci.3642-15.2016 |
0.369 |
|
2015 |
Spinelli KJ, Osterberg VR, Meshul CK, Soumyanath A, Unni VK. Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice. Plos One. 10: e0128510. PMID 26035833 DOI: 10.1371/journal.pone.0128510 |
0.684 |
|
2015 |
Osterberg VR, Spinelli KJ, Weston LJ, Luk KC, Woltjer RL, Unni VK. Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism. Cell Reports. 10: 1252-60. PMID 25732816 DOI: 10.1016/j.celrep.2015.01.060 |
0.73 |
|
2014 |
Spinelli KJ, Taylor JK, Osterberg VR, Churchill MJ, Pollock E, Moore C, Meshul CK, Unni VK. Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2037-50. PMID 24501346 DOI: 10.1523/JNEUROSCI.2581-13.2014 |
0.728 |
|
2013 |
Santiago JA, Scherzer CR, Potashkin JA, Hyman BT, Ivinson AJ, Trisini-Lipsanopoulos A, Dhima K, Bayer S, Lockhart KC, Yi T, Liao Z, Hoesing AN, Duong K, Roderick S, Sudarsky LR, ... ... Unni VK, et al. Specific splice variants are associated with Parkinson's disease Movement Disorders. 28: 1724-1727. PMID 24108702 DOI: 10.1002/mds.25635 |
0.354 |
|
2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Unni VK, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.55 |
|
2012 |
Ebrahimi-Fakhari D, McLean PJ, Unni VK. Alpha-synuclein's degradation in vivo: opening a new (cranial) window on the roles of degradation pathways in Parkinson disease. Autophagy. 8: 281-3. PMID 22301995 DOI: 10.4161/Auto.8.2.18938 |
0.651 |
|
2011 |
Ebrahimi-Fakhari D, Cantuti-Castelvetri I, Fan Z, Rockenstein E, Masliah E, Hyman BT, McLean PJ, Unni VK. Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14508-20. PMID 21994367 DOI: 10.1523/Jneurosci.1560-11.2011 |
0.688 |
|
2011 |
Ding H, Sarokhan AK, Roderick SS, Bakshi R, Maher NE, Ashourian P, Kan CG, Chang S, Santarlasci A, Swords KE, Ravina BM, Hayes MT, Sohur US, Wills AM, Flaherty AW, ... Unni VK, et al. Association of SNCA with Parkinson: replication in the Harvard NeuroDiscovery Center Biomarker Study. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 2283-6. PMID 21953863 DOI: 10.1002/Mds.23934 |
0.445 |
|
2011 |
Unni VK, Ebrahimi-Fakhari D, Vanderburg CR, McLean PJ, Hyman BT. Studying protein degradation pathways in vivo using a cranial window-based approach. Methods (San Diego, Calif.). 53: 194-200. PMID 21187150 DOI: 10.1016/J.Ymeth.2010.12.032 |
0.657 |
|
2010 |
Unni VK, Weissman TA, Rockenstein E, Masliah E, McLean PJ, Hyman BT. In vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility. Plos One. 5: e10589. PMID 20485674 DOI: 10.1371/Journal.Pone.0010589 |
0.756 |
|
2004 |
Unni VK, Zakharenko SS, Zablow L, DeCostanzo AJ, Siegelbaum SA. Calcium release from presynaptic ryanodine-sensitive stores is required for long-term depression at hippocampal CA3-CA3 pyramidal neuron synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9612-22. PMID 15509748 DOI: 10.1523/JNEUROSCI.5583-03.2004 |
0.659 |
|
1999 |
Janz R, Südhof TC, Hammer RE, Unni V, Siegelbaum SA, Bolshakov VY. Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron. 24: 687-700. PMID 10595519 DOI: 10.1016/S0896-6273(00)81122-8 |
0.704 |
|
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