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Heather True - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Findlay AR, Paing MM, Daw JA, Haller M, Bengoechea R, Pittman SK, Li S, Wang F, Miller TM, True HL, Chou TF, Weihl CC. DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1. Molecular Therapy. Nucleic Acids. 32: 937-948. PMID 37346979 DOI: 10.1016/j.omtn.2023.05.017  0.326
2022 Bhadra AK, Rau MJ, Daw JA, Fitzpatrick JAJ, Weihl CC, True HL. Disease-associated mutations within the yeast DNAJB6 homolog Sis1 slow conformer-specific substrate processing and can be corrected by the modulation of nucleotide exchange factors. Nature Communications. 13: 4570. PMID 35931773 DOI: 10.1038/s41467-022-32318-9  0.426
2020 Pullen MY, Weihl CC, True HL. Client processing is altered by novel myopathy-causing mutations in the HSP40 J domain. Plos One. 15: e0234207. PMID 32497100 DOI: 10.1371/Journal.Pone.0234207  0.426
2020 Bengoechea R, Findlay AR, Bhadra AK, Shao H, Stein KC, Pittman SK, Daw J, Gestwicki JE, True HL, Weihl CC. Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy. The Journal of Clinical Investigation. PMID 32427588 DOI: 10.1172/Jci136167  0.334
2017 Arthur LL, Chung JJ, Janakirama P, Keefer KM, Kolotilin I, Pavlovic-Djuranovic S, Chalker DL, Grbic V, Green R, Menassa R, True HL, Skeath JB, Djuranovic S. Corrigendum: Rapid generation of hypomorphic mutations. Nature Communications. 8: 14705. PMID 28205645 DOI: 10.1038/Ncomms14705  0.313
2017 Arthur LL, Chung JJ, Jankirama P, Keefer KM, Kolotilin I, Pavlovic-Djuranovic S, Chalker DL, Grbic V, Green R, Menassa R, True HL, Skeath JB, Djuranovic S. Rapid generation of hypomorphic mutations. Nature Communications. 8: 14112. PMID 28106166 DOI: 10.1038/Ncomms14112  0.311
2016 Keefer KM, True HL. Prion-Associated Toxicity is Rescued by Elimination of Cotranslational Chaperones. Plos Genetics. 12: e1006431. PMID 27828954 DOI: 10.1371/journal.pgen.1006431  0.321
2014 Stein KC, True HL. Structural variants of yeast prions show conformer-specific requirements for chaperone activity. Molecular Microbiology. 93: 1156-71. PMID 25060529 DOI: 10.1111/mmi.12725  0.389
2014 Stein KC, Bengoechea R, Harms MB, Weihl CC, True HL. Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers. The Journal of Biological Chemistry. 289: 21120-30. PMID 24920671 DOI: 10.1074/jbc.M114.572461  0.407
2014 Stein KC, True HL. Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions. Plos Genetics. 10: e1004337. PMID 24811344 DOI: 10.1371/journal.pgen.1004337  0.415
2014 Westergard L, True HL. Wild yeast harbour a variety of distinct amyloid structures with strong prion-inducing capabilities. Molecular Microbiology. 92: 183-93. PMID 24673812 DOI: 10.1111/mmi.12543  0.46
2014 Westergard L, True HL. Extracellular environment modulates the formation and propagation of particular amyloid structures. Molecular Microbiology. 92: 698-715. PMID 24628771 DOI: 10.1111/mmi.12579  0.388
2014 Dulle JE, Stein KC, True HL. Regulation of the Hsp104 middle domain activity is critical for yeast prion propagation. Plos One. 9: e87521. PMID 24466354 DOI: 10.1371/Journal.Pone.0087521  0.316
2013 Huang VJ, Stein KC, True HL. Spontaneous variants of the [RNQ+] prion in yeast demonstrate the extensive conformational diversity possible with prion proteins. Plos One. 8: e79582. PMID 24205387 DOI: 10.1371/journal.pone.0079582  0.447
2013 Dulle JE, Bouttenot RE, Underwood LA, True HL. Soluble oligomers are sufficient for transmission of a yeast prion but do not confer phenotype. The Journal of Cell Biology. 203: 197-204. PMID 24145167 DOI: 10.1083/Jcb.201307040  0.341
2013 Dulle JE, True HL. Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variants. Prion. 7: 394-403. PMID 24064980 DOI: 10.4161/Pri.26547  0.416
2011 Stein KC, True HL. The [RNQ+] prion: a model of both functional and pathological amyloid. Prion. 5: 291-8. PMID 22052347 DOI: 10.4161/pri.18213  0.326
2010 Kalastavadi T, True HL. Analysis of the [RNQ+] prion reveals stability of amyloid fibers as the key determinant of yeast prion variant propagation. The Journal of Biological Chemistry. 285: 20748-55. PMID 20442412 DOI: 10.1074/Jbc.M110.115303  0.385
2010 Lancaster AK, Bardill JP, True HL, Masel J. The spontaneous appearance rate of the yeast prion [PSI+] and its implications for the evolution of the evolvability properties of the [PSI+] system. Genetics. 184: 393-400. PMID 19917766 DOI: 10.1534/Genetics.109.110213  0.593
2010 Lin CA, Ellis SR, True HL. The Sua5 protein is essential for normal translational regulation in yeast. Molecular and Cellular Biology. 30: 354-63. PMID 19884342 DOI: 10.1128/Mcb.00754-09  0.533
2009 Bardill JP, Dulle JE, Fisher JR, True HL. Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion. Prion. 3: 151-60. PMID 19770577 DOI: 10.4161/Pri.3.3.9662  0.628
2009 Bardill JP, True HL. Heterologous prion interactions are altered by mutations in the prion protein Rnq1p. Journal of Molecular Biology. 388: 583-96. PMID 19324054 DOI: 10.1016/j.jmb.2009.03.036  0.629
2009 Strawn LA, Lin CA, Tank EM, Osman MM, Simpson SA, True HL. Mutants of the Paf1 complex alter phenotypic expression of the yeast prion [PSI+]. Molecular Biology of the Cell. 20: 2229-41. PMID 19225160 DOI: 10.1091/Mbc.E08-08-0813  0.618
2009 Tank EM, True HL. Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates. Plos Genetics. 5: e1000382. PMID 19214209 DOI: 10.1371/journal.pgen.1000382  0.34
2008 True HL, Kalastavadi T, Tank EM. Insights into intragenic and extragenic effectors of prion propagation using chimeric prion proteins. Prion. 2: 45-7. PMID 19098443 DOI: 10.4161/Pri.2.2.6509  0.304
2008 Kalastavadi T, True HL. Prion protein insertional mutations increase aggregation propensity but not fiber stability. Bmc Biochemistry. 9: 7. PMID 18366654 DOI: 10.1186/1471-2091-9-7  0.414
2007 Tank EM, Harris DA, Desai AA, True HL. Prion protein repeat expansion results in increased aggregation and reveals phenotypic variability. Molecular and Cellular Biology. 27: 5445-55. PMID 17548473 DOI: 10.1128/MCB.02127-06  0.362
2006 Strawn LA, True HL. Deletion of RNQ1 gene reveals novel functional relationship between divergently transcribed Bik1p/CLIP-170 and Sfi1p in spindle pole body separation. Current Genetics. 50: 347-66. PMID 16972090 DOI: 10.1007/s00294-006-0098-6  0.375
2004 True HL, Berlin I, Lindquist SL. Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits. Nature. 431: 184-7. PMID 15311209 DOI: 10.1038/Nature02885  0.332
2000 True HL, Lindquist SL. A yeast prion provides a mechanism for genetic variation and phenotypic diversity. Nature. 407: 477-83. PMID 11028992 DOI: 10.1038/35035005  0.322
1999 Li PL, Hwang I, Miyagi H, True H, Farrand SK. Essential components of the Ti plasmid trb system, a type IV macromolecular transporter. Journal of Bacteriology. 181: 5033-41. PMID 10438776 DOI: 10.1128/Jb.181.16.5033-5041.1999  0.308
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