J William Harbour - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology, Cell Biology, Oncology

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Field MG, Kuznetsoff JN, Zhang MG, Dollar JJ, Durante MA, Sayegh Y, Decatur CL, Kurtenbach S, Pelaez D, Harbour JW. RB1 loss triggers dependence on ESRRG in retinoblastoma. Science Advances. 8: eabm8466. PMID 35984874 DOI: 10.1126/sciadv.abm8466  0.323
2020 Carbone M, Harbour JW, Brugarolas J, Bononi A, Pagano I, Dey A, Krausz T, Pass HI, Yang H, Gaudino G. Biological Mechanisms and Clinical Significance of Mutations in Human Cancer. Cancer Discovery. PMID 32690542 DOI: 10.1158/2159-8290.Cd-19-1220  0.428
2020 Studenski MT, Patel NV, Markoe A, Harbour JW, Samuels SE. Influence of tumor shape and location in eye plaque brachytherapy dosimetry. Brachytherapy. PMID 32061535 DOI: 10.1016/J.Brachy.2020.01.001  0.348
2020 Durante MA, Rodriguez DA, Kurtenbach S, Kuznetsov JN, Sanchez MI, Decatur CL, Snyder H, Feun LG, Livingstone AS, Harbour JW. Single-cell analysis reveals new evolutionary complexity in uveal melanoma. Nature Communications. 11: 496. PMID 31980621 DOI: 10.1038/S41467-019-14256-1  0.398
2020 Decatur CL, Durante MA, Correa ZM, Aaberg TM, Mruthyunjaya P, Schefler AC, Harbour JW. Abstract 5442: The Collaborative Ocular Oncology Group study number 2: A prospective multi-center evaluation of uveal melanoma prognostic biomarkers Cancer Research. 80: 5442-5442. DOI: 10.1158/1538-7445.Am2020-5442  0.35
2020 Owens DA, Kuznetsov JN, Lopez A, Kurtenbach S, Bilbao D, Roberts ER, Volmar C, Wahlestedt CR, Harbour JW. Abstract 4025: New candidate therapy for BAP1-mutant cancer identified using novel screen Cancer Research. 80: 4025-4025. DOI: 10.1158/1538-7445.Am2020-4025  0.34
2020 Durante MA, Rodriguez DA, Kurtenbach S, Kuznetsoff JN, Sanchez MI, Decatur CL, Snyder H, Feun LG, Livingstone AS, Harbour JW. Abstract 1591: Single cell analysis of uveal melanoma reveals new evolutionary complexity Cancer Research. 80: 1591-1591. DOI: 10.1158/1538-7445.Am2020-1591  0.367
2019 Gonçalves J, Emmons MF, Faião-Flores F, Aplin AE, Harbour JW, Licht JD, Wink MR, Smalley KSM. Decitabine limits escape from MEK inhibition in uveal melanoma. Pigment Cell & Melanoma Research. PMID 31758842 DOI: 10.1111/Pcmr.12849  0.356
2019 Paez-Escamilla M, Walter SD, Mohsenin A, Decatur CL, Harocopos GJ, Dubovy S, Harbour JW. Intraocular Dissemination of Uveal Melanoma Cells Following Radiotherapy: Evolving Management Over the Past Decade. Ophthalmic Surgery, Lasers & Imaging Retina. 50: 573-579. PMID 31589755 DOI: 10.3928/23258160-20190905-06  0.322
2019 Durante MA, Walter SD, Paez-Escamilla M, Tokarev J, Decatur CL, Dubovy SR, Schefler AC, Harbour JW. Intraocular Metastasis in Unilateral Multifocal Uveal Melanoma Without Melanocytosis or Germline BAP1 Mutations. Jama Ophthalmology. PMID 31580399 DOI: 10.1001/Jamaophthalmol.2019.3941  0.357
2019 Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA, Rodriguez DA, King ML, Harbour JW. BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Science Advances. 5: eaax1738. PMID 31555735 DOI: 10.1126/Sciadv.Aax1738  0.381
2019 Field MG, Kuznetsov JN, Bussies PL, Cai L, Alawa KA, Decatur C, Kurtenbach S, Harbour JW. BAP1 loss is associated with DNA methylomic repatterning in highly aggressive Class 2 uveal melanomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31285370 DOI: 10.1158/1078-0432.Ccr-19-0366  0.35
2019 Bowcock AM, Anbunathan H, Verstraten R, Singh AD, Harbour JW. Integrative copy number analysis of uveal melanoma reveals novel candidate genes involved in tumorigenesis including a tumor suppressor role for PHF10/BAF45a. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31227497 DOI: 10.1158/1078-0432.Ccr-18-3052  0.409
2019 Dean MK, Studenski MT, Paez-Escamilla MA, Walter SD, Kwon D, Markoe AM, Harbour JW, Samuels SE. Dosimetric comparison of circular Eye Physics and Collaborative Ocular Melanoma Study plaques to treat uveal melanoma. Brachytherapy. PMID 30797699 DOI: 10.1016/J.Brachy.2019.01.005  0.328
2019 Owens DA, Kuznetsov JN, Kurtenbach S, Agüero T, King ML, Harbour JW. Abstract 5199: A novel role for BAP1 in development and tumor suppression Cancer Research. 79: 5199-5199. DOI: 10.1158/1538-7445.Am2019-5199  0.387
2019 Rodriguez DA, Kuznetsov JN, Sanchez MI, Kurtenbach S, Harbour JW. Abstract 4244: Novel expressed long non-coding RNAs in uveal melanoma Cancer Research. 79: 4244-4244. DOI: 10.1158/1538-7445.Am2019-4244  0.338
2018 Stathias V, Jermakowicz AM, Maloof ME, Forlin M, Walters W, Suter RK, Durante MA, Williams SL, Harbour JW, Volmar CH, Lyons NJ, Wahlestedt C, Graham RM, Ivan ME, Komotar RJ, et al. Drug and disease signature integration identifies synergistic combinations in glioblastoma. Nature Communications. 9: 5315. PMID 30552330 DOI: 10.1038/S41467-018-07659-Z  0.317
2018 Walpole S, Pritchard AL, Cebulla CM, Pilarski R, Stautberg M, Davidorf FH, de la Fouchardière A, Cabaret O, Golmard L, Stoppa-Lyonnet D, Garfield E, Njauw CN, Cheung M, Turunen JA, Repo P, ... ... Harbour JW, et al. Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide. Journal of the National Cancer Institute. PMID 30517737 DOI: 10.1093/Jnci/Djy171  0.385
2018 Paez-Escamilla M, Walter SD, Ramaiya KJ, Harbour JW. Diagnosis of Bilateral Retinocytoma in an Adolescent Patient Using Multimodal Imaging and Genetic Testing. Ophthalmic Surgery and Lasers. 49: 812-814. PMID 30395669 DOI: 10.3928/23258160-20181002-11  0.349
2018 Cai L, Paez-Escamilla M, Walter SD, Tarlan B, Decatur CL, Perez BM, Harbour JW. Gene Expression Profiling and PRAME Status Versus Tumor-Node-Metastasis Staging for Prognostication in Uveal Melanoma. American Journal of Ophthalmology. PMID 30092184 DOI: 10.1016/J.Ajo.2018.07.045  0.355
2018 Field MG, Durante MA, Anbunathan H, Cai LZ, Decatur CL, Bowcock AM, Kurtenbach S, Harbour JW. Punctuated evolution of canonical genomic aberrations in uveal melanoma. Nature Communications. 9: 116. PMID 29317634 DOI: 10.1038/S41467-017-02428-W  0.372
2018 Peng H, Prokop J, Karar J, Park K, Malkowicz SB, Cao L, Harbour JW, Bowcock A, Cheung M, Testa JA, Rauscher FJ. PD46-01 BAP1 DE-UBIQUITINASE IS ALLOSTERICALLY REGULATED BY ASXL1/2: SOMATIC BAP1 MUTATION IN RCC AND OTHER TUMORS INACTIVE THIS REGULATION BY TARGETING MULTIPLE INDEPENDENT DOMAINS Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.2149  0.321
2017 Peng H, Prokop J, Karar J, Park K, Cao L, Harbour JW, Bowcock AM, Malkowicz SB, Cheung M, Testa JR, Rauscher FJ. Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains. Cancer Research. PMID 29284740 DOI: 10.1158/0008-5472.Can-17-2876  0.301
2017 Swaminathan SS, Field MG, Sant D, Wang G, Galor A, Dubovy SR, Harbour JW, Karp CL. Molecular Characteristics of Conjunctival Melanoma Using Whole-Exome Sequencing. Jama Ophthalmology. PMID 29121185 DOI: 10.1001/Jamaophthalmol.2017.4837  0.317
2017 Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, ... ... Harbour JW, et al. Gain-of-function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies. Blood. PMID 29113963 DOI: 10.1182/Blood-2017-06-789669  0.367
2017 Harbour JW, Paez-Escamilla M. Letter to the editor: Comparison of alternative tumor size classifications for posterior uveal melanomas Investigative Ophthalmology & Visual Science. 58: 5444-5444. PMID 29059310 DOI: 10.1167/Iovs.17-22603  0.359
2017 Gezgin G, Luk SJ, Cao J, Dogrusöz M, van der Steen DM, Hagedoorn RS, Krijgsman D, van der Velden PA, Field MG, Luyten GPM, Szuhai K, Harbour JW, Jordanova ES, Heemskerk MHM, Jager MJ. PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma. Jama Ophthalmology. PMID 28448663 DOI: 10.1001/Jamaophthalmol.2017.0729  0.333
2017 Li Z, Zhang P, Yan A, Guo Z, Ban Y, Li J, Chen S, Yang H, He Y, Li J, Guo Y, Zhang W, Hajiramezanali E, An H, Fajardo D, ... Harbour JW, et al. ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis. Science Advances. 3: e1601602. PMID 28116354 DOI: 10.1126/Sciadv.1601602  0.352
2017 Harbour JW. Prognostic Implications of the Largest Basal Tumor Diameter vs the TNM Staging System in Association With the Gene Expression Profile for Uveal Melanoma—Reply Jama Ophthalmology. 135: 175-176. PMID 28056125 DOI: 10.1001/Jamaophthalmol.2016.5109  0.347
2017 Durante M, Field M, Kurtenbach S, Bussies P, Decatur C, Harbour JW. Abstract 4348: Methylation analysis of uveal melanoma reveals definitive patterns in tumors harboring BAP1 mutations Cancer Research. 77: 4348-4348. DOI: 10.1158/1538-7445.Am2017-4348  0.353
2017 Field MG, Anbunathan H, Durante MA, Cai L, Alawa K, Decatur CL, Kurtenbach S, Bowcock A, Harbour JW. Abstract 3390: Clonal evolution in uveal melanoma Cancer Research. 77: 3390-3390. DOI: 10.1158/1538-7445.Am2017-3390  0.398
2017 Kuznetsov JN, Aguero T, Kurtenbach S, Field MG, King ML, Harbour JW. Abstract 1541: The tumor suppressor BAP1 promotes a developmental switch from pluripotency to differentiation Cancer Research. 77: 1541-1541. DOI: 10.1158/1538-7445.Am2017-1541  0.343
2016 Rao RC, Harbour JW. An Iris Tumor. Jama Ophthalmology. PMID 27442779 DOI: 10.1001/Jamaophthalmol.2016.0924  0.349
2016 Fedorenko IV, Evernden B, Kenchappa RS, Sahebjam S, Ryzhova E, Puskas J, McIntosh L, Caceres G, Magliocco A, Etame A, Harbour JW, Smalley KS, Forsyth PA. A rare case of leptomeningeal carcinomatosis in a patient with uveal melanoma: case report and review of literature. Melanoma Research. PMID 27285292 DOI: 10.1097/Cmr.0000000000000274  0.344
2016 Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, ... ... Harbour JW, et al. ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma. Cancer Cell. PMID 27265506 DOI: 10.1016/J.Ccell.2016.04.015  0.323
2016 Walter SD, Chao DL, Feuer W, Schiffman J, Char DH, Harbour JW. Prognostic Implications of Tumor Diameter in Association With Gene Expression Profile for Uveal Melanoma. Jama Ophthalmology. PMID 27123792 DOI: 10.1001/Jamaophthalmol.2016.0913  0.355
2016 Decatur CL, Ong E, Garg N, Anbunathan H, Bowcock AM, Field MG, Harbour JW. Driver Mutations in Uveal Melanoma: Associations With Gene Expression Profile and Patient Outcomes. Jama Ophthalmology. PMID 27123562 DOI: 10.1001/Jamaophthalmol.2016.0903  0.325
2016 Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, et al. The state of melanoma: challenges and opportunities. Pigment Cell & Melanoma Research. PMID 27087480 DOI: 10.1111/Pcmr.12475  0.303
2016 Field MG, Decatur CL, Kurtenbach S, Gezgin G, van der Velden PA, Jager MJ, Kozak KN, Harbour JW. PRAME as an Independent Biomarker for Metastasis in Uveal Melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 22: 1234-42. PMID 26933176 DOI: 10.1158/1078-0432.Ccr-15-2071  0.391
2015 Gustafson CB, Yang C, Dickson KM, Shao H, Van Booven D, Harbour JW, Liu ZJ, Wang G. Epigenetic reprogramming of melanoma cells by vitamin C treatment. Clinical Epigenetics. 7: 51. PMID 25977731 DOI: 10.1186/S13148-015-0087-Z  0.317
2015 Rao RC, Khan M, Badiyan SN, Harbour JW. Gene expression profiling and regression rate of irradiated uveal melanomas. Ophthalmic Surgery, Lasers & Imaging Retina. 46: 333-7. PMID 25856819 DOI: 10.3928/23258160-20150323-06  0.386
2015 Herlihy N, Dogrusöz M, van Essen TH, Harbour JW, van der Velden PA, van Eggermond MC, Haasnoot GW, van den Elsen PJ, Jager MJ. Skewed expression of the genes encoding epigenetic modifiers in high-risk uveal melanoma. Investigative Ophthalmology & Visual Science. 56: 1447-58. PMID 25593028 DOI: 10.1167/Iovs.14-15250  0.358
2015 Field MG, Decatur CL, Harbour JW. Abstract 4262: PRAME as a biomarker for a new molecular subclass of uveal melanoma Cancer Research. 75: 4262-4262. DOI: 10.1158/1538-7445.Am2015-4262  0.413
2015 Walter SD, Harbour JW. Molecular biology of retinoblastoma. Clinical & Translational Oncology. 10: 389-394. DOI: 10.1007/978-3-319-19467-7_1  0.405
2014 van Essen TH, van Pelt SI, Versluis M, Bronkhorst IH, van Duinen SG, Marinkovic M, Kroes WG, Ruivenkamp CA, Shukla S, de Klein A, Kiliç E, Harbour JW, Luyten GP, van der Velden PA, Verdijk RM, et al. Prognostic parameters in uveal melanoma and their association with BAP1 expression. The British Journal of Ophthalmology. 98: 1738-43. PMID 25147369 DOI: 10.1136/Bjophthalmol-2014-305047  0.312
2014 Field MG, Harbour JW. GNAQ/11 mutations in uveal melanoma: is YAP the key to targeted therapy? Cancer Cell. 25: 714-5. PMID 24937456 DOI: 10.1016/J.Ccr.2014.05.028  0.342
2014 Harbour JW, Chao DL. A molecular revolution in uveal melanoma: implications for patient care and targeted therapy. Ophthalmology. 121: 1281-8. PMID 24480708 DOI: 10.1016/J.Ophtha.2013.12.014  0.359
2014 Badiyan SN, Rao RC, Apicelli AJ, Acharya S, Verma V, Garsa AA, DeWees T, Speirs CK, Garcia-Ramirez J, Esthappan J, Grigsby PW, Harbour JW. Outcomes of iodine-125 plaque brachytherapy for uveal melanoma with intraoperative ultrasonography and supplemental transpupillary thermotherapy. International Journal of Radiation Oncology, Biology, Physics. 88: 801-5. PMID 24462385 DOI: 10.1016/J.Ijrobp.2013.12.014  0.313
2014 Harbour JW. A prognostic test to predict the risk of metastasis in uveal melanoma based on a 15-gene expression profile. Methods in Molecular Biology (Clifton, N.J.). 1102: 427-40. PMID 24258991 DOI: 10.1007/978-1-62703-727-3_22  0.352
2013 Matatall KA, Agapova OA, Onken MD, Worley LA, Bowcock AM, Harbour JW. BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma. Bmc Cancer. 13: 371. PMID 23915344 DOI: 10.1186/1471-2407-13-371  0.457
2013 Harbour JW, Chen R. The DecisionDx-UM Gene Expression Profile Test Provides Risk Stratification and Individualized Patient Care in Uveal Melanoma. Plos Currents. 5. PMID 23591547 DOI: 10.1371/Currents.Eogt.Af8Ba80Fc776C8F1Ce8F5Dc485D4A618  0.327
2013 Harbour JW, Roberson ED, Anbunathan H, Onken MD, Worley LA, Bowcock AM. Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma. Nature Genetics. 45: 133-5. PMID 23313955 DOI: 10.1038/Ng.2523  0.355
2013 Dimaras H, Parulekar MV, Kwok G, Simpson ER, Ali A, Halliday W, Shago M, Harbour JW, Héon E, Gallie BL, Chan HS. Molecular testing prognostic of low risk in epithelioid uveal melanoma in a child. The British Journal of Ophthalmology. 97: 323-6. PMID 23292925 DOI: 10.1136/Bjophthalmol-2012-302561  0.331
2013 Harbour JW, Wilson D, Finger PT, Worley LA, Onken MD. Gene expressing profiling of iris melanomas. Ophthalmology. 120: 213, 213.e1-3. PMID 23283188 DOI: 10.1016/J.Ophtha.2012.08.016  0.418
2013 Asnaghi L, Handa JT, Merbs SL, Harbour JW, Eberhart CG. A role for Jag2 in promoting uveal melanoma dissemination and growth. Investigative Ophthalmology & Visual Science. 54: 295-306. PMID 23211831 DOI: 10.1167/Iovs.12-10209  0.4
2012 Daniels AB, Lee JE, MacConaill LE, Palescandolo E, Van Hummelen P, Adams SM, DeAngelis MM, Hahn WC, Gragoudas ES, Harbour JW, Garraway LA, Kim IK. High throughput mass spectrometry-based mutation profiling of primary uveal melanoma. Investigative Ophthalmology & Visual Science. 53: 6991-6. PMID 22977135 DOI: 10.1167/Iovs.12-10427  0.374
2012 Harbour JW. The genetics of uveal melanoma: an emerging framework for targeted therapy. Pigment Cell & Melanoma Research. 25: 171-81. PMID 22268848 DOI: 10.1111/J.1755-148X.2012.00979.X  0.375
2012 Asnaghi L, Ebrahimi KB, Schreck KC, Bar EE, Coonfield ML, Bell WR, Handa J, Merbs SL, Harbour JW, Eberhart CG. Notch signaling promotes growth and invasion in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 654-65. PMID 22228632 DOI: 10.1158/1078-0432.Ccr-11-1406  0.382
2012 Landreville S, Agapova OA, Matatall KA, Kneass ZT, Onken MD, Lee RS, Bowcock AM, Harbour JW. Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 408-16. PMID 22038994 DOI: 10.1158/1078-0432.Ccr-11-0946  0.414
2011 Chan CC, Rubenstein JL, Coupland SE, Davis JL, Harbour JW, Johnston PB, Cassoux N, Touitou V, Smith JR, Batchelor TT, Pulido JS. Primary vitreoretinal lymphoma: a report from an International Primary Central Nervous System Lymphoma Collaborative Group symposium. The Oncologist. 16: 1589-99. PMID 22045784 DOI: 10.1634/Theoncologist.2011-0210  0.346
2011 Landreville S, Agapova OA, Kneass ZT, Salesse C, Harbour JW. ABCB1 identifies a subpopulation of uveal melanoma cells with high metastatic propensity. Pigment Cell & Melanoma Research. 24: 430-7. PMID 21575142 DOI: 10.1111/J.1755-148X.2011.00841.X  0.428
2011 Delston RB, Matatall KA, Sun Y, Onken MD, Harbour JW. p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis. Oncogene. 30: 588-99. PMID 20871633 DOI: 10.1038/Onc.2010.442  0.75
2011 Asnaghi L, Coonfield ML, Schreck KC, Bar EE, Handa J, Merbs S, Ebrahimi KB, Harbour JW, Eberhart CG. Abstract 1415: The Notch ligand Jag 2 promotes growth and invasion in uveal melanoma cells Cancer Research. 71: 1415-1415. DOI: 10.1158/1538-7445.Am2011-1415  0.395
2010 Harbour JW, Onken MD, Roberson ED, Duan S, Cao L, Worley LA, Council ML, Matatall KA, Helms C, Bowcock AM. Frequent mutation of BAP1 in metastasizing uveal melanomas. Science (New York, N.Y.). 330: 1410-3. PMID 21051595 DOI: 10.1126/Science.1194472  0.412
2010 Onken MD, Worley LA, Harbour JW. Association between gene expression profile, proliferation and metastasis in uveal melanoma. Current Eye Research. 35: 857-63. PMID 20795869 DOI: 10.3109/02713683.2010.493265  0.387
2010 Woo KI, Harbour JW. Review of 676 second primary tumors in patients with retinoblastoma: association between age at onset and tumor type. Archives of Ophthalmology (Chicago, Ill. : 1960). 128: 865-70. PMID 20625047 DOI: 10.1001/Archophthalmol.2010.126  0.355
2010 Onken MD, Worley LA, Tuscan MD, Harbour JW. An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal melanoma. The Journal of Molecular Diagnostics : Jmd. 12: 461-8. PMID 20413675 DOI: 10.2353/Jmoldx.2010.090220  0.387
2010 Agapova OA, Person E, Harbour JW. Id2 deficiency promotes metastasis in a mouse model of ocular cancer. Clinical & Experimental Metastasis. 27: 91-6. PMID 20127274 DOI: 10.1007/S10585-010-9304-5  0.36
2010 Asnaghi L, Coonfield ML, Schreck KC, Bar EE, Handa J, Merbs S, Ebrahimi K, Harbour JW, Eberhart CG. Abstract 4141: Notch signaling: A new potential target in the treatment of uveal melanoma Cancer Research. 70: 4141-4141. DOI: 10.1158/1538-7445.Am10-4141  0.395
2008 Landreville S, Agapova OA, Harbour JW. Emerging insights into the molecular pathogenesis of uveal melanoma. Future Oncology (London, England). 4: 629-36. PMID 18922120 DOI: 10.2217/14796694.4.5.629  0.44
2008 Onken MD, Worley LA, Long MD, Duan S, Council ML, Bowcock AM, Harbour JW. Oncogenic mutations in GNAQ occur early in uveal melanoma. Investigative Ophthalmology & Visual Science. 49: 5230-4. PMID 18719078 DOI: 10.1167/Iovs.08-2145  0.305
2008 Onken MD, Worley LA, Harbour JW. A metastasis modifier locus on human chromosome 8p in uveal melanoma identified by integrative genomic analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3737-45. PMID 18559591 DOI: 10.1158/1078-0432.Ccr-07-5144  0.359
2008 Chang SH, Worley LA, Onken MD, Harbour JW. Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis. Melanoma Research. 18: 191-200. PMID 18477893 DOI: 10.1097/Cmr.0B013E3283005270  0.411
2008 Ehlers JP, Worley L, Onken MD, Harbour JW. Integrative genomic analysis of aneuploidy in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 115-22. PMID 18172260 DOI: 10.1158/1078-0432.Ccr-07-1825  0.384
2007 Worley LA, Onken MD, Person E, Robirds D, Branson J, Char DH, Perry A, Harbour JW. Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1466-71. PMID 17332290 DOI: 10.1158/1078-0432.Ccr-06-2401  0.312
2007 Ramaiya KJ, Harbour JW. Current management of uveal melanoma Expert Review of Ophthalmology. 2: 939-946. DOI: 10.1586/17469899.2.6.939  0.365
2007 Ramaiya KJ, Harbour JW. Molecular prognostic testing in uveal melanoma Expert Review of Ophthalmology. 2: 65-69. DOI: 10.1586/17469899.2.1.65  0.35
2006 Delston RB, Harbour JW. Rb at the interface between cell cycle and apoptotic decisions. Current Molecular Medicine. 6: 713-8. PMID 17100597 DOI: 10.2174/1566524010606070713  0.776
2006 Onken MD, Worley LA, Dávila RM, Char DH, Harbour JW. Prognostic testing in uveal melanoma by transcriptomic profiling of fine needle biopsy specimens. The Journal of Molecular Diagnostics : Jmd. 8: 567-73. PMID 17065425 DOI: 10.2353/Jmoldx.2006.060077  0.377
2006 Onken MD, Ehlers JP, Worley LA, Makita J, Yokota Y, Harbour JW. Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas. Cancer Research. 66: 4602-9. PMID 16651410 DOI: 10.1158/0008-5472.Can-05-4196  0.407
2006 Harbour JW. Eye cancer: unique insights into oncogenesis: the Cogan Lecture. Investigative Ophthalmology & Visual Science. 47: 1736-45. PMID 16638975 DOI: 10.1167/Iovs.05-1291  0.383
2006 Ehlers JP, Harbour JW. Molecular pathobiology of uveal melanoma. International Ophthalmology Clinics. 46: 167-80. PMID 16365562 DOI: 10.1097/01.Iio.0000195855.31324.Db  0.316
2005 Onken MD, Lin AY, Worley LA, Folberg R, Harbour JW. Association between microarray gene expression signature and extravascular matrix patterns in primary uveal melanomas. American Journal of Ophthalmology. 140: 748-9. PMID 16226537 DOI: 10.1016/J.Ajo.2005.04.024  0.303
2005 Faulkner-Jones BE, Foster WJ, Harbour JW, Smith ME, Dávila RM. Fine needle aspiration biopsy with adjunct immunohistochemistry in intraocular tumor management. Acta Cytologica. 49: 297-308. PMID 15966293 DOI: 10.1159/000326153  0.321
2005 Ehlers JP, Worley L, Onken MD, Harbour JW. DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3609-13. PMID 15897555 DOI: 10.1158/1078-0432.Ccr-04-1941  0.309
2005 Sun Y, Tran BN, Worley LA, Delston RB, Harbour JW. Functional analysis of the p53 pathway in response to ionizing radiation in uveal melanoma. Investigative Ophthalmology & Visual Science. 46: 1561-4. PMID 15851551 DOI: 10.1167/iovs.04-1362  0.753
2005 Ehlers JP, Harbour JW. NBS1 expression as a prognostic marker in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 1849-53. PMID 15756009 DOI: 10.1158/1078-0432.Ccr-04-2054  0.377
2005 Lieman JH, Worley LA, Harbour JW. Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase. The Journal of Biological Chemistry. 280: 10484-90. PMID 15640164 DOI: 10.1074/Jbc.M409371200  0.761
2005 Loercher AE, Tank EM, Delston RB, Harbour JW. MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A. The Journal of Cell Biology. 168: 35-40. PMID 15623583 DOI: 10.1083/Jcb.200410115  0.762
2004 Onken MD, Worley LA, Ehlers JP, Harbour JW. Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death. Cancer Research. 64: 7205-9. PMID 15492234 DOI: 10.1158/0008-5472.Can-04-1750  0.365
2004 Espinoza G, Rosenblatt B, Harbour JW. Optical coherence tomography in the evaluation of retinal changes associated with suspicious choroidal melanocytic tumors. American Journal of Ophthalmology. 137: 90-5. PMID 14700649 DOI: 10.1016/S0002-9394(03)00868-7  0.322
2003 Loercher AE, Harbour JW. Molecular genetics of uveal melanoma. Current Eye Research. 27: 69-74. PMID 14632157 DOI: 10.1076/Ceyr.27.2.69.15952  0.317
2003 Foster WJ, Fuller CE, Perry A, Harbour JW. Status of the NF1 tumor suppressor locus in uveal melanoma. Archives of Ophthalmology (Chicago, Ill. : 1960). 121: 1311-5. PMID 12963615 DOI: 10.1001/Archopht.121.9.1311  0.388
2003 Hurst EA, Harbour JW, Cornelius LA. Ocular melanoma: a review and the relationship to cutaneous melanoma. Archives of Dermatology. 139: 1067-73. PMID 12925397 DOI: 10.1001/Archderm.139.8.1067  0.344
2003 Ma D, Zhou P, Harbour JW. Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb. The Journal of Biological Chemistry. 278: 19358-66. PMID 12646568 DOI: 10.1074/Jbc.M301761200  0.428
2003 Harbour JW. Radiotherapy of Intraocular and Orbital Tumors, 2nd Revised ed Archives of Ophthalmology. 121: 1517-1517. DOI: 10.1001/Archopht.121.10.1517-A  0.347
2002 Brantley MA, Worley L, Harbour JW. Altered expression of Rb and p53 in uveal melanomas following plaque radiotherapy. American Journal of Ophthalmology. 133: 242-8. PMID 11812429 DOI: 10.1016/S0002-9394(01)01362-9  0.396
2002 Finger PT, Harbour JW, Karcioglu ZA. Risk factors for metastasis in retinoblastoma. Survey of Ophthalmology. 47: 1-16. PMID 11801265 DOI: 10.1016/S0039-6257(01)00279-X  0.331
2001 Harbour JW. Molecular basis of low-penetrance retinoblastoma. Archives of Ophthalmology (Chicago, Ill. : 1960). 119: 1699-704. PMID 11709023 DOI: 10.1001/Archopht.119.11.1699  0.361
2001 Brantley MA, Harbour JW. The molecular biology of retinoblastoma. Ocular Immunology and Inflammation. 9: 1-8. PMID 11262663 DOI: 10.1076/Ocii.9.1.1.3984  0.435
2000 Brantley MA, Harbour JW. Deregulation of the Rb and p53 pathways in uveal melanoma. The American Journal of Pathology. 157: 1795-801. PMID 11106551 DOI: 10.1016/S0002-9440(10)64817-1  0.427
2000 Harbour JW, Dean DC. Chromatin remodeling and Rb activity. Current Opinion in Cell Biology. 12: 685-9. PMID 11063932 DOI: 10.1016/S0955-0674(00)00152-6  0.347
2000 Harbour JW, Dean DC. The Rb/E2F pathway: Expanding roles and emerging paradigms Genes and Development. 14: 2393-2409. PMID 11018009 DOI: 10.1101/Gad.813200  0.321
2000 Brantley M.A. J, Harbour JW. Inactivation of retinoblastoma protein in uveal melanoma by phosphorylation of sites in the COOH-terminal region Cancer Research. 60: 4320-4323. PMID 10969768  0.317
2000 Harbour JW, Dean DC. Rb function in cell-cycle regulation and apoptosis Nature Cell Biology. 2: E65-E67. PMID 10783254 DOI: 10.1038/35008695  0.364
2000 Zhang HS, Gavin M, Dahiya A, Postigo AA, Ma D, Luo RX, Harbour JW, Dean DC. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell. 101: 79-89. PMID 10778858 DOI: 10.1016/S0092-8674(00)80625-X  0.314
1999 Harbour JW. Tumor suppressor genes in ophthalmology Survey of Ophthalmology. 44: 235-246. PMID 10588442 DOI: 10.1016/S0039-6257(99)00102-2  0.413
1997 Char D, Weidner N, Ahn J, Harbour JW. Solitary fibrous tumor of the orbit Orbit. 16: 113-118. DOI: 10.3109/01676839709019126  0.357
1996 Harbour JW, Murray TG, Byrne SF, Hughes JR, Gendron EK, Ehlies FJ, Markoe AM. Intraoperative echographic localization of iodine 125 episcleral radioactive plaques for posterior uveal melanoma. Retina-the Journal of Retinal and Vitreous Diseases. 16: 129-134. PMID 8724957 DOI: 10.1097/00006982-199616020-00008  0.31
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