| Year |
Citation |
Score |
| 2023 |
Ferguson CA, Firulli BA, Zoia M, Osterwalder M, Firulli AB. Identification and characterization of Hand2 upstream genomic enhancers active in developing stomach and limbs. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 37551791 DOI: 10.1002/dvdy.646 |
0.414 |
|
| 2023 |
George RM, Firulli BA, Podicheti R, Rusch DB, Mannion BJ, Pennacchio LA, Osterwalder M, Firulli AB. Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis. Development (Cambridge, England). PMID 36620995 DOI: 10.1242/dev.201341 |
0.489 |
|
| 2022 |
George RM, Guo S, Firulli BA, Rubart M, Firulli AB. Neonatal Deletion of and within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis. Journal of Cardiovascular Development and Disease. 9. PMID 35877576 DOI: 10.3390/jcdd9070214 |
0.386 |
|
| 2022 |
Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, et al. Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma. Nature Communications. 13: 1677. PMID 35354817 DOI: 10.1038/s41467-022-29311-7 |
0.426 |
|
| 2021 |
Abe M, Cox TC, Firulli AB, Kanai SM, Dalhka J, Lim KC, Engel JD, Clouthier DE. GATA3 is essential for separating patterning domains during facial morphogenesis. Development (Cambridge, England). PMID 34383890 DOI: 10.1242/dev.199534 |
0.311 |
|
| 2021 |
George RM, Firulli AB. Deletion of a lncRNA-Containing Septum Transversum Enhancer Alters lncRNA Expression but Is Not Required for Expression. Journal of Cardiovascular Development and Disease. 8. PMID 34064373 DOI: 10.3390/jcdd8050050 |
0.336 |
|
| 2021 |
George RM, Firulli AB. Epigenetics and Heart Development. Frontiers in Cell and Developmental Biology. 9: 637996. PMID 34026751 DOI: 10.3389/fcell.2021.637996 |
0.392 |
|
| 2021 |
Vincentz JW, Firulli BA, Toolan KP, Osterwalder M, Pennacchio LA, Firulli AB. HAND transcription factors cooperatively specify the aorta and pulmonary trunk. Developmental Biology. 476: 1-10. PMID 33757801 DOI: 10.1016/j.ydbio.2021.03.011 |
0.531 |
|
| 2020 |
George RM, Maldonado-Velez G, Firulli AB. The heart of the neural crest: cardiac neural crest cells in development and regeneration. Development (Cambridge, England). 147. PMID 33060096 DOI: 10.1242/dev.188706 |
0.348 |
|
| 2020 |
Durbin MD, O'Kane J, Lorentz S, Firulli AB, Ware SM. SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Developmental Biology. PMID 32511952 DOI: 10.1016/j.ydbio.2020.05.013 |
0.409 |
|
| 2020 |
Vincentz JW, Clouthier DE, Firulli AB. Mis-Expression of a Cranial Neural Crest Cell-Specific Gene Program in Cardiac Neural Crest Cells Modulates HAND Factor Expression, Causing Cardiac Outflow Tract Phenotypes. Journal of Cardiovascular Development and Disease. 7. PMID 32325975 DOI: 10.3390/Jcdd7020013 |
0.497 |
|
| 2019 |
Firulli BA, Firulli AB. Partially Penetrant Cardiac Neural Crest Defects in Hand1 Phosphomutant Mice: Dimer Choice That Is Not So Critical. Pediatric Cardiology. PMID 31338559 DOI: 10.1007/s00246-019-02162-8 |
0.452 |
|
| 2019 |
Firulli BA, George R, Harkin J, Toolan KP, Gao H, Liu Y, Zhang W, Field LJ, Liu Y, Shou W, Payne RM, Rubart-von der Lohe M, Firulli AB. HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure. Cardiovascular Research. PMID 31286141 DOI: 10.1093/Cvr/Cvz182 |
0.387 |
|
| 2018 |
George RM, Firulli AB. Hand Factors in Cardiac Development. Anatomical Record (Hoboken, N.J. : 2007). PMID 30288953 DOI: 10.1002/Ar.23910 |
0.486 |
|
| 2018 |
Miao L, Li J, Li J, Tian X, Lu Y, Hu S, Shieh D, Kanai R, Zhou BY, Zhou B, Liu J, Firulli AB, Martin JF, Singer H, Zhou B, et al. Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification. Scientific Reports. 8: 2678. PMID 29422515 DOI: 10.1038/S41598-018-20917-W |
0.604 |
|
| 2017 |
Vincentz JW, Toolan KP, Zhang W, Firulli AB. Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function. Plos Genetics. 13: e1006922. PMID 28732025 DOI: 10.1371/journal.pgen.1006922 |
0.467 |
|
| 2017 |
Firulli BA, Milliar H, Toolan KP, Harkin J, Fuchs RK, Robling AG, Firulli AB. Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis. Development (Cambridge, England). PMID 28576769 DOI: 10.1242/dev.149963 |
0.424 |
|
| 2016 |
Vincentz JW, Casasnovas JJ, Barnes RM, Que J, Clouthier DE, Wang J, Firulli AB. Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap. Proceedings of the National Academy of Sciences of the United States of America. PMID 27335460 DOI: 10.1073/Pnas.1603930113 |
0.586 |
|
| 2014 |
VanDusen NJ, Casanovas J, Vincentz JW, Firulli BA, Osterwalder M, Lopez-Rios J, Zeller R, Zhou B, Grego-Bessa J, De La Pompa JL, Shou W, Firulli AB. Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium. Cell Reports. 9: 2071-83. PMID 25497097 DOI: 10.1016/J.Celrep.2014.11.021 |
0.761 |
|
| 2014 |
Firulli BA, Fuchs RK, Vincentz JW, Clouthier DE, Firulli AB. Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis. Development (Cambridge, England). 141: 3050-61. PMID 25053435 DOI: 10.1242/Dev.107680 |
0.39 |
|
| 2014 |
Schindler YL, Garske KM, Wang J, Firulli BA, Firulli AB, Poss KD, Yelon D. Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration. Development (Cambridge, England). 141: 3112-22. PMID 25038045 DOI: 10.1242/Dev.106336 |
0.412 |
|
| 2014 |
VanDusen NJ, Vincentz JW, Firulli BA, Howard MJ, Rubart M, Firulli AB. Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death. Developmental Biology. 388: 149-58. PMID 24565998 DOI: 10.1016/j.ydbio.2014.02.010 |
0.75 |
|
| 2014 |
Vincentz JW, Firulli AB. The Cardiac Neural Crest and Their Role in Development and Disease Neural Crest Cells: Evolution, Development and Disease. 205-229. DOI: 10.1016/B978-0-12-401730-6.00012-0 |
0.398 |
|
| 2013 |
Zhang W, Firulli AB, Shou W. A glimpse of Cre-mediated controversies in epicardial signalling. Cardiovascular Research. 100: 347-9. PMID 24148896 DOI: 10.1093/Cvr/Cvt241 |
0.371 |
|
| 2013 |
Chen H, Zhang W, Sun X, Yoshimoto M, Chen Z, Zhu W, Liu J, Shen Y, Yong W, Li D, Zhang J, Lin Y, Li B, VanDusen NJ, Snider P, ... ... Firulli AB, et al. Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development (Cambridge, England). 140: 1946-57. PMID 23571217 DOI: 10.1242/Dev.089920 |
0.733 |
|
| 2013 |
Vincentz JW, Firulli BA, Lin A, Spicer DB, Howard MJ, Firulli AB. Twist1 controls a cell-specification switch governing cell fate decisions within the cardiac neural crest. Plos Genetics. 9: e1003405. PMID 23555309 DOI: 10.1371/Journal.Pgen.1003405 |
0.4 |
|
| 2012 |
VanDusen NJ, Firulli AB. Twist factor regulation of non-cardiomyocyte cell lineages in the developing heart. Differentiation; Research in Biological Diversity. 84: 79-88. PMID 22516205 DOI: 10.1016/j.diff.2012.03.002 |
0.74 |
|
| 2012 |
Vincentz JW, Rubart M, Firulli AB. Ontogeny of cardiac sympathetic innervation and its implications for cardiac disease. Pediatric Cardiology. 33: 923-8. PMID 22395650 DOI: 10.1007/s00246-012-0248-1 |
0.39 |
|
| 2012 |
Vincentz JW, VanDusen NJ, Fleming AB, Rubart M, Firulli BA, Howard MJ, Firulli AB. A Phox2- and Hand2-dependent Hand1 cis-regulatory element reveals a unique gene dosage requirement for Hand2 during sympathetic neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2110-20. PMID 22323723 DOI: 10.1523/JNEUROSCI.3584-11.2012 |
0.737 |
|
| 2011 |
Vincentz JW, Barnes RM, Firulli AB. Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defects. Birth Defects Research. Part a, Clinical and Molecular Teratology. 91: 485-94. PMID 21462297 DOI: 10.1002/Bdra.20796 |
0.662 |
|
| 2011 |
Barnes RM, Firulli BA, VanDusen NJ, Morikawa Y, Conway SJ, Cserjesi P, Vincentz JW, Firulli AB. Hand2 loss-of-function in Hand1-expressing cells reveals distinct roles in epicardial and coronary vessel development. Circulation Research. 108: 940-9. PMID 21350214 DOI: 10.1161/Circresaha.110.233171 |
0.75 |
|
| 2010 |
Barnes RM, Firulli BA, Conway SJ, Vincentz JW, Firulli AB. Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 3086-97. PMID 20882677 DOI: 10.1002/Dvdy.22428 |
0.663 |
|
| 2010 |
Firulli BA, McConville DP, Byers JS, Vincentz JW, Barnes RM, Firulli AB. Analysis of a Hand1 hypomorphic allele reveals a critical threshold for embryonic viability. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 2748-60. PMID 20737509 DOI: 10.1002/Dvdy.22402 |
0.66 |
|
| 2010 |
Tang S, Snider P, Firulli AB, Conway SJ. Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects. Developmental Biology. 344: 233-47. PMID 20457144 DOI: 10.1016/j.ydbio.2010.05.004 |
0.422 |
|
| 2010 |
Firulli AB, Firulli BA, Wang J, Rogers RH, Conway SJ. Gene replacement strategies to test the functional redundancy of basic helix-loop-helix transcription factor. Pediatric Cardiology. 31: 438-48. PMID 20155416 DOI: 10.1007/s00246-010-9669-x |
0.508 |
|
| 2010 |
Holler KL, Hendershot TJ, Troy SE, Vincentz JW, Firulli AB, Howard MJ. Targeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract development. Developmental Biology. 341: 291-304. PMID 20144608 DOI: 10.1016/j.ydbio.2010.02.001 |
0.449 |
|
| 2010 |
Conway SJ, Firulli B, Firulli AB. A bHLH code for cardiac morphogenesis. Pediatric Cardiology. 31: 318-24. PMID 20033146 DOI: 10.1007/s00246-009-9608-x |
0.44 |
|
| 2009 |
Barnes RM, Firulli AB. A twist of insight - the role of Twist-family bHLH factors in development. The International Journal of Developmental Biology. 53: 909-24. PMID 19378251 DOI: 10.1387/Ijdb.082747Rb |
0.534 |
|
| 2008 |
Vincentz JW, Barnes RM, Firulli BA, Conway SJ, Firulli AB. Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 3809-19. PMID 19035347 DOI: 10.1002/Dvdy.21803 |
0.629 |
|
| 2008 |
Firulli AB, Conway SJ. Phosphoregulation of Twist1 provides a mechanism of cell fate control. Current Medicinal Chemistry. 15: 2641-7. PMID 18855684 DOI: 10.2174/092986708785908987 |
0.41 |
|
| 2008 |
Vincentz JW, Barnes RM, Rodgers R, Firulli BA, Conway SJ, Firulli AB. An absence of Twist1 results in aberrant cardiac neural crest morphogenesis. Developmental Biology. 320: 131-9. PMID 18539270 DOI: 10.1016/J.Ydbio.2008.04.037 |
0.64 |
|
| 2008 |
Hendershot TJ, Liu H, Clouthier DE, Shepherd IT, Coppola E, Studer M, Firulli AB, Pittman DL, Howard MJ. Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons. Developmental Biology. 319: 179-91. PMID 18501887 DOI: 10.1016/J.Ydbio.2008.03.036 |
0.415 |
|
| 2008 |
Snider P, Hinton RB, Moreno-Rodriguez RA, Wang J, Rogers R, Lindsley A, Li F, Ingram DA, Menick D, Field L, Firulli AB, Molkentin JD, Markwald R, Conway SJ. Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart. Circulation Research. 102: 752-60. PMID 18296617 DOI: 10.1161/Circresaha.107.159517 |
0.526 |
|
| 2007 |
Firulli BA, Redick BA, Conway SJ, Firulli AB. Mutations within helix I of Twist1 result in distinct limb defects and variation of DNA binding affinities. The Journal of Biological Chemistry. 282: 27536-46. PMID 17652084 DOI: 10.1074/jbc.M702613200 |
0.369 |
|
| 2007 |
Snider P, Olaopa M, Firulli AB, Conway SJ. Cardiovascular development and the colonizing cardiac neural crest lineage. Thescientificworldjournal. 7: 1090-113. PMID 17619792 DOI: 10.1100/tsw.2007.189 |
0.446 |
|
| 2007 |
Lindsley A, Snider P, Zhou H, Rogers R, Wang J, Olaopa M, Kruzynska-Frejtag A, Koushik SV, Lilly B, Burch JB, Firulli AB, Conway SJ. Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer. Developmental Biology. 307: 340-55. PMID 17540359 DOI: 10.1016/j.ydbio.2007.04.041 |
0.405 |
|
| 2004 |
Firulli AB, Conway SJ. Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation. Birth Defects Research. Part C, Embryo Today : Reviews. 72: 151-61. PMID 15269889 DOI: 10.1002/bdrc.20009 |
0.462 |
|
| 2003 |
Firulli BA, Howard MJ, McDaid JR, McIlreavey L, Dionne KM, Centonze VE, Cserjesi P, Virshup DM, Firulli AB. PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation. Molecular Cell. 12: 1225-37. PMID 14636580 DOI: 10.1016/S1097-2765(03)00425-8 |
0.326 |
|
| 2003 |
Xu H, Firulli AB, Zhang X, Howard MJ. HAND2 synergistically enhances transcription of dopamine-beta-hydroxylase in the presence of Phox2a. Developmental Biology. 262: 183-93. PMID 14512028 DOI: 10.1016/S0012-1606(03)00361-0 |
0.386 |
|
| 2003 |
Firulli AB. A HANDful of questions: the molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors. Gene. 312: 27-40. PMID 12909338 DOI: 10.1016/S0378-1119(03)00669-3 |
0.472 |
|
| 2002 |
Thattaliyath BD, Firulli BA, Firulli AB. The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene. Journal of Molecular and Cellular Cardiology. 34: 1335-44. PMID 12392994 DOI: 10.1016/S0022-2828(02)92085-7 |
0.469 |
|
| 2002 |
Thattaliyath BD, Livi CB, Steinhelper ME, Toney GM, Firulli AB. HAND1 and HAND2 are expressed in the adult-rodent heart and are modulated during cardiac hypertrophy. Biochemical and Biophysical Research Communications. 297: 870-5. PMID 12359233 DOI: 10.1016/S0006-291X(02)02297-0 |
0.444 |
|
| 2002 |
Firulli AB, Thattaliyath BD. Transcription factors in cardiogenesis: the combinations that unlock the mysteries of the heart. International Review of Cytology. 214: 1-62. PMID 11893163 DOI: 10.1016/S0074-7696(02)14002-2 |
0.465 |
|
| 2000 |
McFadden DG, Charité J, Richardson JA, Srivastava D, Firulli AB, Olson EN. A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart. Development (Cambridge, England). 127: 5331-41. PMID 11076755 |
0.489 |
|
| 2000 |
Firulli BA, Hadzic DB, McDaid JR, Firulli AB. The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function* Journal of Biological Chemistry. 275: 33567-33573. PMID 10924525 DOI: 10.1074/jbc.M005888200 |
0.443 |
|
| 1998 |
Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nature Genetics. 18: 266-70. PMID 9500550 DOI: 10.1038/Ng0398-266 |
0.701 |
|
| 1997 |
Firulli AB, Olson EN. Modular regulation of muscle gene transcription: A mechanism for muscle cell diversity Trends in Genetics. 13: 364-369. PMID 9287492 DOI: 10.1016/S0168-9525(97)01171-2 |
0.475 |
|
| 1996 |
Molkentin JD, Firulli AB, Black BL, Martin JF, Hustad CM, Copeland N, Jenkins N, Lyons G, Olson EN. MEF2B is a potent transactivator expressed in early myogenic lineages Molecular and Cellular Biology. 16: 3814-3824. PMID 8668199 DOI: 10.1128/Mcb.16.7.3814 |
0.688 |
|
| 1996 |
Firulli AB, Miano JM, Bi W, Johnson AD, Casscells W, Olson EN, Schwarz JJ. Myocyte enhancer binding factor-2 expression and activity in vascular smooth muscle cells: Association with the activated phenotype Circulation Research. 78: 196-204. PMID 8575062 DOI: 10.1161/01.Res.78.2.196 |
0.705 |
|
| 1996 |
Miano JM, Firulli AB, Olson EN, Hara P, Giachelli CM, Schwartz SM. Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells Proceedings of the National Academy of Sciences of the United States of America. 93: 900-905. PMID 8570656 DOI: 10.1073/Pnas.93.2.900 |
0.457 |
|
| 1994 |
Lilly B, Galewsky S, Firulli AB, Schulz RA, Olson EN. D-MEF2: a MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 91: 5662-6. PMID 8202544 DOI: 10.1073/Pnas.91.12.5662 |
0.513 |
|
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