| Year |
Citation |
Score |
| 2020 |
Khanna A, Côté A, Arora S, Moine L, Gehling VS, Brenneman J, Cantone N, Stuckey JI, Apte S, Ramakrishnan A, Bruderek K, Bradley WD, Audia JE, Cummings RT, Sims RJ, et al. Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time. Acs Medicinal Chemistry Letters. 11: 1205-1212. PMID 32551002 DOI: 10.1021/Acsmedchemlett.0C00045 |
0.304 |
|
| 2019 |
Taplin M, Hussain A, Shah S, Shore ND, Edenfield WJ, Sartor OA, Nordquist LT, Agrawal M, Clark W, Wise DR, Oh WK, Fleming MT, Butrynski JE, Chatta GS, Bupathi M, ... ... Bradley WD, et al. Abstract CT094: Phase Ib results of ProSTAR: CPI-1205, EZH2 inhibitor, combined with enzalutamide (E) or abiraterone/prednisone (A/P) in patients with metastatic castration-resistant prostate cancer (mCRPC) Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct094 |
0.304 |
|
| 2016 |
Bradley WD, Yuan C, Zhao F, Lee C, Williamson KE, Arora S, Hatton C, Bryant BM, Trojer P. Abstract B31: EZH2 suppresses the interferon-stimulated gene response in non-Hodgkin lymphoma Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B31 |
0.371 |
|
| 2015 |
Simpson MA, Bradley WD, Harburger D, Parsons M, Calderwood DA, Koleske AJ. Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase. The Journal of Biological Chemistry. 290: 8360-72. PMID 25694433 DOI: 10.1074/Jbc.M115.638874 |
0.625 |
|
| 2014 |
Bradley WD, Arora S, Busby J, Balasubramanian S, Gehling VS, Nasveschuk CG, Vaswani RG, Yuan CC, Hatton C, Zhao F, Williamson KE, Iyer P, Méndez J, Campbell R, Cantone N, et al. EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation. Chemistry & Biology. 21: 1463-75. PMID 25457180 DOI: 10.1016/J.Chembiol.2014.09.017 |
0.327 |
|
| 2012 |
Warren MS, Bradley WD, Gourley SL, Lin YC, Simpson MA, Reichardt LF, Greer CA, Taylor JR, Koleske AJ. Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2824-34. PMID 22357865 DOI: 10.1523/Jneurosci.3942-11.2012 |
0.643 |
|
| 2012 |
Su F, Bradley WD, Wang Q, Yang H, Xu L, Higgins B, Kolinsky K, Packman K, Kim MJ, Trunzer K, Lee RJ, Schostack K, Carter J, Albert T, Germer S, et al. Resistance to selective BRAF inhibition can be mediated by modest upstream pathway activation. Cancer Research. 72: 969-78. PMID 22205714 DOI: 10.1158/0008-5472.Can-11-1875 |
0.516 |
|
| 2012 |
Yang H, Higgins B, Kolinsky K, Packman K, Bradley WD, Lee RJ, Schostack K, Simcox ME, Kopetz S, Heimbrook D, Lestini B, Bollag G, Su F. Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer. Cancer Research. 72: 779-89. PMID 22180495 DOI: 10.1158/0008-5472.Can-11-2941 |
0.522 |
|
| 2009 |
Bradley WD, Koleske AJ. Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts. Journal of Cell Science. 122: 3441-54. PMID 19759284 DOI: 10.1242/Jcs.039859 |
0.613 |
|
| 2007 |
Sfakianos MK, Eisman A, Gourley SL, Bradley WD, Scheetz AJ, Settleman J, Taylor JR, Greer CA, Williamson A, Koleske AJ. Inhibition of Rho via Arg and p190RhoGAP in the postnatal mouse hippocampus regulates dendritic spine maturation, synapse and dendrite stability, and behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10982-92. PMID 17928439 DOI: 10.1523/Jneurosci.0793-07.2007 |
0.594 |
|
| 2007 |
Peacock JG, Miller AL, Bradley WD, Rodriguez OC, Webb DJ, Koleske AJ. The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin. Molecular Biology of the Cell. 18: 3860-72. PMID 17652459 DOI: 10.1091/Mbc.E07-01-0075 |
0.666 |
|
| 2006 |
Bradley WD, Hernández SE, Settleman J, Koleske AJ. Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane. Molecular Biology of the Cell. 17: 4827-36. PMID 16971514 DOI: 10.1091/Mbc.E06-02-0132 |
0.647 |
|
| 2003 |
Feng J, Bradley WD, Roberts MF. Optimizing the interfacial binding and activity of a bacterial phosphatidylinositol-specific phospholipase C. The Journal of Biological Chemistry. 278: 24651-7. PMID 12714598 DOI: 10.1074/Jbc.M301207200 |
0.306 |
|
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