Andrew Randall - Publications

Affiliations: 
University of Bristol, Bristol, England, United Kingdom 

145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Smithers HE, Terry JR, Brown JT, Randall AD. Sex-associated differences in excitability within the bed nucleus of the stria terminalis are reflective of cell-type. Neurobiology of Stress. 10: 100143. PMID 30937349 DOI: 10.1016/j.ynstr.2018.100143  0.92
2018 Winter MJ, Windell D, Metz J, Matthews P, Pinion J, Brown JT, Hetheridge MJ, Ball JS, Owen SF, Redfern WS, Moger J, Randall AD, Tyler CR. Author Correction: 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Scientific Reports. 8: 15903. PMID 30349014 DOI: 10.1038/s41598-018-32731-5  0.92
2018 Telezhkin V, Straccia M, Yarova P, Pardo M, Yung S, Vinh NN, Hancock JM, Barriga GG, Brown DA, Rosser AE, Brown JT, Canals JM, Randall AD, Allen ND, Kemp PJ. Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. Pflugers Archiv : European Journal of Physiology. PMID 29797067 DOI: 10.1007/s00424-018-2155-7  0.92
2018 Ridler T, Matthews P, Phillips KG, Randall AD, Brown JT. Initiation and slow propagation of epileptiform activity from ventral to dorsal medial entorhinal cortex is constrained by an inhibitory gradient. The Journal of Physiology. PMID 29604046 DOI: 10.1113/JP275871  0.92
2018 Scullion SE, Barker GRI, Warburton EC, Randall AD, Brown JT. Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy. Neurochemical Research. PMID 29484523 DOI: 10.1007/s11064-018-2487-x  0.92
2017 Smithers HE, Terry JR, Brown JT, Randall AD. Aging-Associated Changes to Intrinsic Neuronal Excitability in the Bed Nucleus of the Stria Terminalis Is Cell Type-Dependent. Frontiers in Aging Neuroscience. 9: 424. PMID 29311907 DOI: 10.3389/fnagi.2017.00424  0.92
2017 Palombo F, Tamagnini F, Jeynes JCG, Mattana S, Swift I, Nallala J, Hancock J, Brown JT, Randall AD, Stone N. Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry. The Analyst. PMID 29230441 DOI: 10.1039/c7an01747b  0.92
2017 Tamagnini F, Walsh DA, Brown JT, Bondulich MK, Hanger DP, Randall AD. Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein. Neurobiology of Aging. 60: 44-56. PMID 28917666 DOI: 10.1016/j.neurobiolaging.2017.07.005  0.92
2017 Winter MJ, Windell D, Metz J, Matthews P, Pinion J, Brown JT, Hetheridge MJ, Ball JS, Owen SF, Redfern WS, Moger J, Randall AD, Tyler CR. 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Scientific Reports. 7: 6581. PMID 28747660 DOI: 10.1038/s41598-017-06646-6  0.92
2017 Manso Y, Holland PR, Kitamura A, Szymkowiak S, Duncombe J, Hennessy E, Searcy JL, Marangoni M, Randall AD, Brown JT, McColl BW, Horsburgh K. Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease. Glia. PMID 28722234 DOI: 10.1002/glia.23190  0.92
2017 Jackson JS, Witton J, Johnson JD, Ahmed Z, Ward M, Randall AD, Hutton ML, Isaac JT, O'Neill MJ, Ashby MC. Altered Synapse Stability in the Early Stages of Tauopathy. Cell Reports. 18: 3063-3068. PMID 28355559 DOI: 10.1016/j.celrep.2017.03.013  0.44
2017 Walsh DA, Brown JT, Randall AD. In vitro characterisation of cell-level neurophysiological diversity in the rostral nucleus reuniens of adult mice. The Journal of Physiology. PMID 28295330 DOI: 10.1113/JP273915  0.92
2016 Kemp PJ, Rushton DJ, Yarova PL, Schnell C, Geater C, Hancock JM, Wieland A, Hughes A, Badder L, Cope E, Riccardi D, Randall AD, Brown JT, Allen ND, Telezhkin V. Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA. The Journal of Physiology. PMID 27616476 DOI: 10.1113/JP270655  0.92
2016 Booth CA, Witton J, Nowacki J, Tsaneva-Atanasova K, Jones MW, Randall AD, Brown JT. Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 350-63. PMID 26758828 DOI: 10.1523/JNEUROSCI.2151-15.2016  0.92
2016 Booth CA, Ridler T, Murray TK, Ward MA, de Groot E, Goodfellow M, Phillips KG, Randall AD, Brown JT. Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 312-24. PMID 26758825 DOI: 10.1523/JNEUROSCI.2845-14.2016  0.92
2015 Telezhkin V, Schnell C, Yarova PL, Yung S, Sanders P, Cope E, Hughes A, Thompson BA, Geater C, Hancock JM, Joy S, Badder L, Connor-Robson N, Comella A, Straccia M, ... ... Randall AD, et al. Forced cell-cycle exit and modulation of GABAA, CREB and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology. Cell Physiology. ajpcell.00166.2015. PMID 26718628 DOI: 10.1152/ajpcell.00166.2015  0.92
2015 Tamagnini F, Novelia J, Kerrigan TL, Brown JT, Tsaneva-Atanasova K, Randall AD. Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice. Frontiers in Cellular Neuroscience. 9: 372. PMID 26528126 DOI: 10.3389/fncel.2015.00372  1
2015 Mehrban N, Zhu B, Tamagnini F, Young FI, Wasmuth A, Hudson KL, Thomson AR, Birchall MA, Randall AD, Song B, Woolfson DN. Functionalized α-Helical Peptide Hydrogels for Neural Tissue Engineering. Acs Biomaterials Science & Engineering. 1: 431-439. PMID 26240838 DOI: 10.1021/acsbiomaterials.5b00051  0.56
2015 Witton J, Padmashri R, Zinyuk LE, Popov VI, Kraev I, Line SJ, Jensen TP, Tedoldi A, Cummings DM, Tybulewicz VL, Fisher EM, Bannerman DM, Randall AD, Brown JT, Edwards FA, et al. Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome. Nature Neuroscience. 18: 1291-8. PMID 26237367 DOI: 10.1038/nn.4072  0.92
2015 Nistor PA, May PW, Tamagnini F, Randall AD, Caldwell MA. Long-term culture of pluripotent stem-cell-derived human neurons on diamond--A substrate for neurodegeneration research and therapy. Biomaterials. 61: 139-49. PMID 26002787 DOI: 10.1016/j.biomaterials.2015.04.050  0.56
2015 Dawson N, Kurihara M, Thomson DM, Winchester CL, McVie A, Hedde JR, Randall AD, Shen S, Seymour PA, Hughes ZA, Dunlop J, Brown JT, Brandon NJ, Morris BJ, Pratt JA. Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1. Translational Psychiatry. 5: e569. PMID 25989143 DOI: 10.1038/tp.2015.60  0.92
2015 Tamagnini F, Scullion S, Brown JT, Randall AD. Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid β peptide. Hippocampus. 25: 786-97. PMID 25515596 DOI: 10.1002/hipo.22403  1
2015 Witton J, Padmashri R, Zinyuk LE, Popov VI, Kraev I, Line SJ, Jensen TP, Tedoldi A, Cummings DM, Tybulewicz VLJ, Fisher EMC, Bannerman DM, Randall AD, Brown JT, Edwards FA, et al. Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome Nature Neuroscience. DOI: 10.1038/nn.4072  1
2015 Nistor PA, May PW, Tamagnini F, Randall AD, Caldwell MA. Long-term culture of pluripotent stem-cell-derived human neurons on diamond - A substrate for neurodegeneration research and therapy Biomaterials. 61: 139-149. DOI: 10.1016/j.biomaterials.2015.04.050  1
2014 Witton J, Staniaszek LE, Bartsch U, Randall AD, Jones MW, Brown JT. Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia. The Journal of Physiology. PMID 25480798 DOI: 10.1113/jphysiol.2014.282889  1
2014 Curtis DJ, Sood A, Phillips TJ, Leinster VH, Nishiguchi A, Coyle C, Lacharme-Lora L, Beaumont O, Kemp H, Goodall R, Cornes L, Giugliano M, Barone RA, Matsusaki M, Akashi M, ... ... Randall A, et al. Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions. Experimental Neurology. 261: 386-95. PMID 24818543 DOI: 10.1016/j.expneurol.2014.05.003  1
2014 Booth CA, Brown JT, Randall AD. Neurophysiological modification of CA1 pyramidal neurons in a transgenic mouse expressing a truncated form of disrupted-in-schizophrenia 1. The European Journal of Neuroscience. 39: 1074-90. PMID 24712988 DOI: 10.1111/ejn.12549  1
2014 Randall AD, Kurihara M, Brandon NJ, Brown JT. Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system. The European Journal of Neuroscience. 39: 1068-73. PMID 24712987 DOI: 10.1111/ejn.12500  1
2014 Tamagnini F, Scullion S, Brown JT, Randall AD. Low concentrations of the solvent dimethyl sulphoxide alter intrinsic excitability properties of cortical and hippocampal pyramidal cells. Plos One. 9: e92557. PMID 24647720 DOI: 10.1371/journal.pone.0092557  1
2014 Kerrigan TL, Brown JT, Randall AD. Characterization of altered intrinsic excitability in hippocampal CA1 pyramidal cells of the Aβ-overproducing PDAPP mouse. Neuropharmacology. 79: 515-24. PMID 24055500 DOI: 10.1016/j.neuropharm.2013.09.004  1
2013 Corbett BF, Leiser SC, Ling HP, Nagy R, Breysse N, Zhang X, Hazra A, Brown JT, Randall AD, Wood A, Pangalos MN, Reinhart PH, Chin J. Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7020-6. PMID 23595759 DOI: 10.1523/JNEUROSCI.2325-12.2013  0.48
2013 Kerrigan TL, Randall AD. A new player in the "synaptopathy" of Alzheimer's disease - arc/arg 3.1. Frontiers in Neurology. 4: 9. PMID 23407382 DOI: 10.3389/fneur.2013.00009  1
2013 Brown J, Hainsworth AH, Stefani A, Randall AD. Whole-cell patch-clamp recording of voltage-sensitive Ca²⁺ channel currents in single cells: heterologous expression systems and neurones. Methods in Molecular Biology (Clifton, N.J.). 937: 123-48. PMID 23007583 DOI: 10.1007/978-1-62703-086-1_7  1
2013 Brown J, Hainsworth AH, Stefani A, Randall AD. Whole-cell patch-clamp recording of voltage-sensitive Ca2+ channel currents in single cells: Heterologous expression systems and neurones Methods in Molecular Biology. 937: 123-148. DOI: 10.1007/978-1-62703-86-1_7  1
2012 Forsyth LH, Witton J, Brown JT, Randall AD, Jones MW. In Vitro and In Vivo Recording of Local Field Potential Oscillations in Mouse Hippocampus. Current Protocols in Mouse Biology. 2: 273-94. PMID 26069015 DOI: 10.1002/9780470942390.mo120089  0.92
2012 Petrovic MM, Nowacki J, Olivo V, Tsaneva-Atanasova K, Randall AD, Mellor JR. Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampus. Plos One. 7: e30402. PMID 22348007 DOI: 10.1371/journal.pone.0030402  1
2012 Randall AD, Booth C, Brown JT. Age-related changes to Na+ channel gating contribute to modified intrinsic neuronal excitability. Neurobiology of Aging. 33: 2715-20. PMID 22284989 DOI: 10.1016/j.neurobiolaging.2011.12.030  1
2011 Sitzia F, Brown JT, Randall AD, Dunlop J. Voltage- and Temperature-Dependent Allosteric Modulation of α7 Nicotinic Receptors by PNU120596. Frontiers in Pharmacology. 2: 81. PMID 22207849 DOI: 10.3389/fphar.2011.00081  1
2011 Sood A, Salih S, Roh D, Lacharme-Lora L, Parry M, Hardiman B, Keehan R, Grummer R, Winterhager E, Gokhale PJ, Andrews PW, Abbott C, Forbes K, Westwood M, Aplin JD, ... ... Randall A, et al. Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness. Nature Nanotechnology. 6: 824-33. PMID 22056725 DOI: 10.1038/nnano.2011.188  1
2011 Brown JT, Chin J, Leiser SC, Pangalos MN, Randall AD. Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease. Neurobiology of Aging. 32: 2109.e1-14. PMID 21794952 DOI: 10.1016/j.neurobiolaging.2011.05.025  1
2011 Sukoff Rizzo SJ, Leonard SK, Gilbert A, Dollings P, Smith DL, Zhang MY, Di L, Platt BJ, Neal S, Dwyer JM, Bender CN, Zhang J, Lock T, Kowal D, Kramer A, ... Randall A, et al. The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise? The Journal of Pharmacology and Experimental Therapeutics. 338: 345-52. PMID 21508084 DOI: 10.1124/jpet.110.177378  1
2011 Brown JT, Booth CA, Randall AD. Synaptic activation of mGluR1 generates persistent depression of a fast after-depolarizing potential in CA3 pyramidal neurons. The European Journal of Neuroscience. 33: 879-89. PMID 21269340 DOI: 10.1111/j.1460-9568.2010.07565.x  1
2011 Nowacki J, Osinga HM, Brown JT, Randall AD, Tsaneva-Atanasova K. A unified model of CA1/3 pyramidal cells: an investigation into excitability. Progress in Biophysics and Molecular Biology. 105: 34-48. PMID 20887748 DOI: 10.1016/j.pbiomolbio.2010.09.020  1
2010 Witton J, Brown JT, Jones MW, Randall AD. Altered synaptic plasticity in the mossy fibre pathway of transgenic mice expressing mutant amyloid precursor protein. Molecular Brain. 3: 32. PMID 21040543 DOI: 10.1186/1756-6606-3-32  1
2010 Pangalos MN, Randall AD. Introduction to the special issue on Alzheimer's disease. Neuropharmacology. 59: 219-20. PMID 20728692 DOI: 10.1016/j.neuropharm.2010.07.021  1
2010 Chater TE, Henley JM, Brown JT, Randall AD. Voltage- and temperature-dependent gating of heterologously expressed channelrhodopsin-2. Journal of Neuroscience Methods. 193: 7-13. PMID 20691205 DOI: 10.1016/j.jneumeth.2010.07.033  1
2010 Randall AD, Witton J, Booth C, Hynes-Allen A, Brown JT. The functional neurophysiology of the amyloid precursor protein (APP) processing pathway. Neuropharmacology. 59: 243-67. PMID 20167227 DOI: 10.1016/j.neuropharm.2010.02.011  1
2009 Oldfield S, Hancock J, Mason A, Hobson SA, Wynick D, Kelly E, Randall AD, Marrion NV. Receptor-mediated suppression of potassium currents requires colocalization within lipid rafts. Molecular Pharmacology. 76: 1279-89. PMID 19726551 DOI: 10.1124/mol.109.058008  1
2009 Nicholson E, Randall AD. Na(v)1.5 sodium channels in a human microglial cell line. Journal of Neuroimmunology. 215: 25-30. PMID 19698999 DOI: 10.1016/j.jneuroim.2009.07.009  1
2009 Clement JP, Randall AD, Brown JT. Metabotropic glutamate receptor 1 activity generates persistent, N-methyl-D-aspartate receptor-dependent depression of hippocampal pyramidal cell excitability. The European Journal of Neuroscience. 29: 2347-62. PMID 19490024 DOI: 10.1111/j.1460-9568.2009.06780.x  1
2009 Brown JT, Randall AD. Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons. The Journal of Physiology. 587: 1265-81. PMID 19171653 DOI: 10.1113/jphysiol.2008.167007  1
2009 Dunlop J, Lock T, Jow B, Sitzia F, Grauer S, Jow F, Kramer A, Bowlby MR, Randall A, Kowal D, Gilbert A, Comery TA, Larocque J, Soloveva V, Brown J, et al. Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide). The Journal of Pharmacology and Experimental Therapeutics. 328: 766-76. PMID 19050173 DOI: 10.1124/jpet.108.146514  1
2008 Piccinin S, Thuault SJ, Doherty AJ, Brown JT, Randall AD, Davies CH, Bortolotto ZA, Collingridge GL. The induction of long-term plasticity of non-synaptic, synchronized activity by the activation of group I mGluRs. Neuropharmacology. 55: 459-63. PMID 18619627 DOI: 10.1016/j.neuropharm.2008.05.017  1
2008 Langmead CJ, Austin NE, Branch CL, Brown JT, Buchanan KA, Davies CH, Forbes IT, Fry VA, Hagan JJ, Herdon HJ, Jones GA, Jeggo R, Kew JN, Mazzali A, Melarange R, ... ... Randall AD, et al. Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1. British Journal of Pharmacology. 154: 1104-15. PMID 18454168 DOI: 10.1038/bjp.2008.152  1
2007 Brown JT, Davies CH, Randall AD. Synaptic activation of GABA(B) receptors regulates neuronal network activity and entrainment. The European Journal of Neuroscience. 25: 2982-90. PMID 17561812 DOI: 10.1111/j.1460-9568.2007.05544.x  1
2007 Gunthorpe MJ, Hannan SL, Smart D, Jerman JC, Arpino S, Smith GD, Brough S, Wright J, Egerton J, Lappin SC, Holland VA, Winborn K, Thompson M, Rami HK, Randall A, et al. Characterization of SB-705498, a potent and selective vanilloid receptor-1 (VR1/TRPV1) antagonist that inhibits the capsaicin-, acid-, and heat-mediated activation of the receptor. The Journal of Pharmacology and Experimental Therapeutics. 321: 1183-92. PMID 17392405 DOI: 10.1124/jpet.106.116657  1
2006 Teriakidis A, Brown JT, Randall A. Frequency-dependent inhibition of antidromic hippocampal compound action potentials by anti-convulsants. Pharmacological Reports : Pr. 58: 859-69. PMID 17220543  1
2006 Fonfria E, Mattei C, Hill K, Brown JT, Randall A, Benham CD, Skaper SD, Campbell CA, Crook B, Murdock PR, Wilson JM, Maurio FP, Owen DE, Tilling PL, McNulty S. TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia. Journal of Receptor and Signal Transduction Research. 26: 179-98. PMID 16777714 DOI: 10.1080/10799890600637522  1
2006 Lappin SC, Randall AD, Gunthorpe MJ, Morisset V. TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation. European Journal of Pharmacology. 540: 73-81. PMID 16737693 DOI: 10.1016/j.ejphar.2006.04.046  1
2006 Randall A, McNaughton N, Green P. Properties of voltage-gated Na+ channels in the human rhabdomyosarcoma cell-line SJ-RH30: conventional and automated patch clamp analysis. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 54: 118-28. PMID 16675265 DOI: 10.1016/j.phrs.2006.03.005  1
2006 Rami HK, Thompson M, Stemp G, Fell S, Jerman JC, Stevens AJ, Smart D, Sargent B, Sanderson D, Randall AD, Gunthorpe MJ, Davis JB. Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development. Bioorganic & Medicinal Chemistry Letters. 16: 3287-91. PMID 16580202 DOI: 10.1016/j.bmcl.2006.03.030  1
2006 Piccinin S, Randall AD, Brown JT. KCNQ/Kv7 channel regulation of hippocampal gamma-frequency firing in the absence of synaptic transmission. Journal of Neurophysiology. 95: 3105-12. PMID 16467425 DOI: 10.1152/jn.01083.2005  1
2006 Gill CH, Brown JT, Shivji N, Lappin SC, Farmer C, Randall A, McNaughton NC, Cobb SR, Davies CH. Inhibition of Ih reduces epileptiform activity in rodent hippocampal slices. Synapse (New York, N.Y.). 59: 308-16. PMID 16421904 DOI: 10.1002/syn.20242  1
2006 Spencer JP, Weil A, Hill K, Hussain I, Richardson JC, Cusdin FS, Chen YH, Randall AD. Transgenic mice over-expressing human beta-amyloid have functional nicotinic alpha 7 receptors. Neuroscience. 137: 795-805. PMID 16303255 DOI: 10.1016/j.neuroscience.2005.10.007  1
2006 Hill K, Tigue NJ, Kelsell RE, Benham CD, McNulty S, Schaefer M, Randall AD. Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones. Neuropharmacology. 50: 89-97. PMID 16260005 DOI: 10.1016/j.neuropharm.2005.08.021  1
2006 Brown JT, Teriakidis A, Randall AD. A pharmacological investigation of the role of GLUK5-containing receptors in kainate-driven hippocampal gamma band oscillations. Neuropharmacology. 50: 47-56. PMID 16153668 DOI: 10.1016/j.neuropharm.2005.07.017  1
2005 Hainsworth AH, Randall AD, Stefani A. Whole-cell patch clamp recording of voltage-sensitive Ca²+ channel currents: heterologous expression systems and dissociated brain neurons. Methods in Molecular Biology (Clifton, N.J.). 312: 161-79. PMID 21341098 DOI: 10.1385/1-59259-949-4:161  1
2005 Thuault SJ, Brown JT, Calver AR, Collingridge GL, Randall A, Davies CH. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit. Epilepsy Research. 65: 41-51. PMID 15979855 DOI: 10.1016/j.eplepsyres.2005.04.004  1
2005 Weil A, Moore SE, Waite NJ, Randall A, Gunthorpe MJ. Conservation of functional and pharmacological properties in the distantly related temperature sensors TRVP1 and TRPM8. Molecular Pharmacology. 68: 518-27. PMID 15911692 DOI: 10.1124/mol.105.012146  1
2005 McNamara FN, Randall A, Gunthorpe MJ. Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1). British Journal of Pharmacology. 144: 781-90. PMID 15685214 DOI: 10.1038/sj.bjp.0706040  1
2005 Brown JT, Randall A. Gabapentin fails to alter P/Q-type Ca2+ channel-mediated synaptic transmission in the hippocampus in vitro. Synapse (New York, N.Y.). 55: 262-9. PMID 15668986 DOI: 10.1002/syn.20115  1
2005 Gitterman DP, Wilson J, Randall AD. Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line. The Journal of Physiology. 562: 759-69. PMID 15576453 DOI: 10.1113/jphysiol.2004.075069  1
2005 Brown JT, Richardson JC, Collingridge GL, Randall AD, Davies CH. Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice. Hippocampus. 15: 110-7. PMID 15390159 DOI: 10.1002/hipo.20036  1
2004 Hill K, McNulty S, Randall AD. Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole. Naunyn-Schmiedeberg's Archives of Pharmacology. 370: 227-37. PMID 15549272 DOI: 10.1007/s00210-004-0981-y  1
2004 Spencer JP, Brown JT, Richardson JC, Medhurst AD, Sehmi SS, Calver AR, Randall AD. Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease. Neuroscience. 129: 49-54. PMID 15489027 DOI: 10.1016/j.neuroscience.2004.06.070  1
2004 Thuault SJ, Brown JT, Sheardown SA, Jourdain S, Fairfax B, Spencer JP, Restituito S, Nation JH, Topps S, Medhurst AD, Randall AD, Couve A, Moss SJ, Collingridge GL, Pangalos MN, et al. The GABA(B2) subunit is critical for the trafficking and function of native GABA(B) receptors. Biochemical Pharmacology. 68: 1655-66. PMID 15451409 DOI: 10.1016/j.bcp.2004.07.032  1
2004 Gill CH, Randall A, Bates SA, Hill K, Owen D, Larkman PM, Cairns W, Yusaf SP, Murdock PR, Strijbos PJ, Powell AJ, Benham CD, Davies CH. Characterization of the human HCN1 channel and its inhibition by capsazepine. British Journal of Pharmacology. 143: 411-21. PMID 15351778 DOI: 10.1038/sj.bjp.0705945  1
2004 Hill K, Benham CD, McNulty S, Randall AD. Flufenamic acid is a pH-dependent antagonist of TRPM2 channels. Neuropharmacology. 47: 450-60. PMID 15275834 DOI: 10.1016/j.neuropharm.2004.04.014  1
2004 McNaughton NC, Davies CH, Randall A. Inhibition of alpha(1E) Ca(2+) channels by carbonic anhydrase inhibitors. Journal of Pharmacological Sciences. 95: 240-7. PMID 15215649 DOI: JST.JSTAGE/jphs/FP0040032  1
2004 Rami HK, Thompson M, Wyman P, Jerman JC, Egerton J, Brough S, Stevens AJ, Randall AD, Smart D, Gunthorpe MJ, Davis JB. Discovery of small molecule antagonists of TRPV1. Bioorganic & Medicinal Chemistry Letters. 14: 3631-4. PMID 15203132 DOI: 10.1016/j.bmcl.2004.05.028  1
2004 Gadalla AE, Pearson T, Currie AJ, Dale N, Hawley SA, Sheehan M, Hirst W, Michel AD, Randall A, Hardie DG, Frenguelli BG. AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus. Journal of Neurochemistry. 88: 1272-82. PMID 15009683 DOI: 10.1046/j.1471-4159.2003.02253.x  1
2004 Gunthorpe MJ, Rami HK, Jerman JC, Smart D, Gill CH, Soffin EM, Luis Hannan S, Lappin SC, Egerton J, Smith GD, Worby A, Howett L, Owen D, Nasir S, Davies CH, ... ... Randall AD, et al. Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist. Neuropharmacology. 46: 133-49. PMID 14654105 DOI: 10.1016/S0028-3908(03)00305-8  1
2003 Brown JT, Gill CH, Farmer CE, Lanneau C, Randall AD, Pangalos MN, Collingridge GL, Davies CH. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices of GABAB1 receptor subunit knockout mice. Epilepsy Research. 57: 121-36. PMID 15013053 DOI: 10.1016/j.eplepsyres.2003.10.013  1
2003 Hainsworth AH, McNaughton NC, Pereverzev A, Schneider T, Randall AD. Actions of sipatrigine, 202W92 and lamotrigine on R-type and T-type Ca2+ channel currents. European Journal of Pharmacology. 467: 77-80. PMID 12706458 DOI: 10.1016/S0014-2999(03)01625-X  1
2002 Riccio A, Medhurst AD, Mattei C, Kelsell RE, Calver AR, Randall AD, Benham CD, Pangalos MN. mRNA distribution analysis of human TRPC family in CNS and peripheral tissues. Brain Research. Molecular Brain Research. 109: 95-104. PMID 12531519 DOI: 10.1016/S0169-328X(02)00527-2  1
2002 Thuault SJ, Davies CH, Randall AD, Collingridge GL. Group I mGluRs modulate the pattern of non-synaptic epileptiform activity in the hippocampus. Neuropharmacology. 43: 141-6. PMID 12213268 DOI: 10.1016/S0028-3908(02)00095-3  1
2002 Lanneau C, Harries MH, Ray AM, Cobb SR, Randall A, Davies CH. Complex interactions between mGluR1 and mGluR5 shape neuronal network activity in the rat hippocampus. Neuropharmacology. 43: 131-40. PMID 12213267 DOI: 10.1016/S0028-3908(02)00086-2  1
2002 Smith GD, Gunthorpe MJ, Kelsell RE, Hayes PD, Reilly P, Facer P, Wright JE, Jerman JC, Walhin JP, Ooi L, Egerton J, Charles KJ, Smart D, Randall AD, Anand P, et al. TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature. 418: 186-90. PMID 12077606 DOI: 10.1038/nature00894  1
2002 Benham CD, Davis JB, Randall AD. Vanilloid and TRP channels: a family of lipid-gated cation channels. Neuropharmacology. 42: 873-88. PMID 12069898 DOI: 10.1016/S0028-3908(02)00047-3  1
2002 Trevisani M, Smart D, Gunthorpe MJ, Tognetto M, Barbieri M, Campi B, Amadesi S, Gray J, Jerman JC, Brough SJ, Owen D, Smith GD, Randall AD, Harrison S, Bianchi A, et al. Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nature Neuroscience. 5: 546-51. PMID 11992116 DOI: 10.1038/nn852  1
2002 Warre RC, McNaughton NC, Randall AD. Differential discrimination of fast and slow synaptic waveforms by two low-voltage-activated calcium channels. Neuroscience. 110: 375-88. PMID 11958878 DOI: 10.1016/S0306-4522(01)00576-0  1
2002 Gunthorpe MJ, Benham CD, Randall A, Davis JB. The diversity in the vanilloid (TRPV) receptor family of ion channels. Trends in Pharmacological Sciences. 23: 183-91. PMID 11931994 DOI: 10.1016/S0165-6147(02)01999-5  1
2002 Riccio A, Mattei C, Kelsell RE, Medhurst AD, Calver AR, Randall AD, Davis JB, Benham CD, Pangalos MN. Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx. The Journal of Biological Chemistry. 277: 12302-9. PMID 11805119 DOI: 10.1074/jbc.M112313200  1
2001 McNaughton NC, Green PJ, Randall AD. Inhibition of human alpha1E subunit-mediated ca2+ channels by the antipsychotic agent chlorpromazine. Acta Physiologica Scandinavica. 173: 401-8. PMID 11903132 DOI: 10.1046/j.1365-201X.2001.00914.x  1
2001 Caputi L, Hainsworth AH, Lavaroni F, Leach MJ, McNaughton NC, Mercuri NB, Randall AD, Spadoni F, Swan JH, Stefani A. Neuroprotective actions in vivo and electrophysiological actions in vitro of 202W92. Brain Research. 919: 259-68. PMID 11701138 DOI: 10.1016/S0006-8993(01)03029-3  1
2001 Gunthorpe MJ, Smith GD, Davis JB, Randall AD. Characterisation of a human acid-sensing ion channel (hASIC1a) endogenously expressed in HEK293 cells. PflüGers Archiv : European Journal of Physiology. 442: 668-74. PMID 11512022 DOI: 10.1007/s004240100584  1
2001 Watson J, Roberts C, Scott C, Kendall I, Collin L, Day NC, Harries MH, Soffin E, Davies CH, Randall AD, Heightman T, Gaster L, Wyman P, Parker C, Price GW, et al. SB-272183, a selective 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptor antagonist in native tissue. British Journal of Pharmacology. 133: 797-806. PMID 11454652 DOI: 10.1038/sj.bjp.0704133  1
2001 Prosser HM, Gill CH, Hirst WD, Grau E, Robbins M, Calver A, Soffin EM, Farmer CE, Lanneau C, Gray J, Schenck E, Warmerdam BS, Clapham C, Reavill C, Rogers DC, ... ... Randall A, et al. Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice. Molecular and Cellular Neurosciences. 17: 1059-70. PMID 11414794 DOI: 10.1006/mcne.2001.0995  1
2001 Green PJ, Warre R, Hayes PD, McNaughton NC, Medhurst AD, Pangalos M, Duckworth DM, Randall AD. Kinetic modification of the alpha(1I) subunit-mediated T-type Ca(2+) channel by a human neuronal Ca(2+) channel gamma subunit. The Journal of Physiology. 533: 467-78. PMID 11389205 DOI: 10.1111/j.1469-7793.2001.0467a.x  1
2001 Mellor JR, Randall AD. Synaptically released neurotransmitter fails to desensitize postsynaptic GABA(A) receptors in cerebellar cultures. Journal of Neurophysiology. 85: 1847-57. PMID 11353001  1
2001 Hervieu GJ, Cluderay JE, Gray CW, Green PJ, Ranson JL, Randall AD, Meadows HJ. Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS. Neuroscience. 103: 899-919. PMID 11301200 DOI: 10.1016/S0306-4522(01)00030-6  1
2001 Smart D, Jerman JC, Gunthorpe MJ, Brough SJ, Ranson J, Cairns W, Hayes PD, Randall AD, Davis JB. Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology. European Journal of Pharmacology. 417: 51-8. PMID 11301059 DOI: 10.1016/S0014-2999(01)00901-3  1
2001 Meadows HJ, Randall AD. Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel. Neuropharmacology. 40: 551-9. PMID 11249964 DOI: 10.1016/S0028-3908(00)00189-1  1
2001 Meadows HJ, Chapman CG, Duckworth DM, Kelsell RE, Murdock PR, Nasir S, Rennie G, Randall AD. The neuroprotective agent sipatrigine (BW619C89) potently inhibits the human tandem pore-domain K(+) channels TREK-1 and TRAAK. Brain Research. 892: 94-101. PMID 11172753 DOI: 10.1016/S0006-8993(00)03239-X  1
2000 Fearon IM, Randall AD, Perez-Reyes E, Peers C. Modulation of recombinant T-type Ca2+ channels by hypoxia and glutathione. PflüGers Archiv : European Journal of Physiology. 441: 181-8. PMID 11211102 DOI: 10.1007/s004240000424  1
2000 Hayes P, Meadows HJ, Gunthorpe MJ, Harries MH, Duckworth DM, Cairns W, Harrison DC, Clarke CE, Ellington K, Prinjha RK, Barton AJ, Medhurst AD, Smith GD, Topp S, Murdock P, ... ... Randall AD, et al. Cloning and functional expression of a human orthologue of rat vanilloid receptor-1. Pain. 88: 205-15. PMID 11050376 DOI: 10.1016/S0304-3959(00)00353-5  1
2000 McNaughton NC, Warre R, Cooper DG, Nasir S, Ranson JL, Randall A. Potent inhibition of a recombinant low voltage-activated Ca(2+) channel by SB-209712. European Journal of Pharmacology. 407: 53-60. PMID 11050290 DOI: 10.1016/S0014-2999(00)00740-8  1
2000 Chapman CG, Meadows HJ, Godden RJ, Campbell DA, Duckworth M, Kelsell RE, Murdock PR, Randall AD, Rennie GI, Gloger IS. Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel. Brain Research. Molecular Brain Research. 82: 74-83. PMID 11042359 DOI: 10.1016/S0169-328X(00)00183-2  1
2000 Warre R, Randall A. Modulation of the deactivation kinetics of a recombinant rat T-type Ca(2+) channel by prior inactivation. Neuroscience Letters. 293: 216-20. PMID 11036199 DOI: 10.1016/S0304-3940(00)01531-7  1
2000 Gunthorpe MJ, Harries MH, Prinjha RK, Davis JB, Randall A. Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1). The Journal of Physiology. 525: 747-59. PMID 10856126  1
2000 Mellor JR, Wisden W, Randall AD. Somato-synaptic variation of GABA(A) receptors in cultured murine cerebellar granule cells: investigation of the role of the alpha6 subunit. Neuropharmacology. 39: 1495-513. PMID 10854895 DOI: 10.1016/S0028-3908(00)00007-1  1
2000 Mellor JR, Gunthorpe MJ, Randall AD. The taurine uptake inhibitor guanidinoethyl sulphonate is an agonist at gamma-aminobutyric acid(A) receptors in cultured murine cerebellar granule cells. Neuroscience Letters. 286: 25-8. PMID 10822144 DOI: 10.1016/S0304-3940(00)01082-X  1
2000 Davis JB, Gray J, Gunthorpe MJ, Hatcher JP, Davey PT, Overend P, Harries MH, Latcham J, Clapham C, Atkinson K, Hughes SA, Rance K, Grau E, Harper AJ, Pugh PL, ... ... Randall A, et al. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature. 405: 183-7. PMID 10821274 DOI: 10.1038/35012076  1
2000 McNaughton NC, Hainsworth AH, Green PJ, Randall AD. Inhibition of recombinant low-voltage-activated Ca(2+) channels by the neuroprotective agent BW619C89 (Sipatrigine). Neuropharmacology. 39: 1247-53. PMID 10760366 DOI: 10.1016/S0028-3908(99)00201-4  1
2000 Leao RM, Mellor JR, Randall AD. Tonic benzodiazepine-sensitive GABAergic inhibition in cultured rodent cerebellar granule cells. Neuropharmacology. 39: 990-1003. PMID 10727709 DOI: 10.1016/S0028-3908(99)00177-X  1
2000 Smart D, Gunthorpe MJ, Jerman JC, Nasir S, Gray J, Muir AI, Chambers JK, Randall AD, Davis JB. The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). British Journal of Pharmacology. 129: 227-30. PMID 10694225 DOI: 10.1038/sj.bjp.0703050  1
1999 Randall A, Benham CD. Recent advances in the molecular understanding of voltage-gated Ca2+ channels. Molecular and Cellular Neurosciences. 14: 255-72. PMID 10588383 DOI: 10.1006/mcne.1999.0795  1
1999 McNaughton NC, White C, Clark B, Bath C, Bleakman D, Randall AD. Electrophysiological characterisation of the human N-type Ca2+ channel III: pH-dependent inhibition by a synthetic macrocyclic polyamine. Neuropharmacology. 38: 19-38. PMID 10193896 DOI: 10.1016/S0028-3908(98)00156-7  1
1998 Williamson AV, Mellor JR, Grant AL, Randall AD. Properties of GABA(A) receptors in cultured rat oligodendrocyte progenitor cells. Neuropharmacology. 37: 859-73. PMID 9776382 DOI: 10.1016/S0028-3908(98)00016-1  1
1998 Frischknecht F, Randall AD. Voltage- and ligand-gated ion channels in floor plate neuroepithelia of the rat. Neuroscience. 85: 1135-49. PMID 9681952 DOI: 10.1016/S0306-4522(97)00641-6  1
1998 McNaughton NC, Bleakman D, Randall AD. Electrophysiological characterisation of the human N-type Ca2+ channel II: activation and inactivation by physiological patterns of activity. Neuropharmacology. 37: 67-81. PMID 9680260 DOI: 10.1016/S0028-3908(97)00153-6  1
1998 Mellor JR, Merlo D, Jones A, Wisden W, Randall AD. Mouse cerebellar granule cell differentiation: electrical activity regulates the GABAA receptor alpha 6 subunit gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2822-33. PMID 9525999  1
1998 Randall AD. The molecular basis of voltage-gated Ca2+ channel diversity: is it time for T? The Journal of Membrane Biology. 161: 207-13. PMID 9493126 DOI: 10.1007/s002329900327  1
1998 Mellor JR, Randall AD. Voltage-dependent deactivation and desensitization of GABA responses in cultured murine cerebellar granule cells. The Journal of Physiology. 506: 377-90. PMID 9490866 DOI: 10.1111/j.1469-7793.1998.377bw.x  1
1997 McNaughton NC, Leach MJ, Hainsworth AH, Randall AD. Inhibition of human N-type voltage-gated Ca2+ channels by the neuroprotective agent BW619C89. Neuropharmacology. 36: 1795-8. PMID 9517454 DOI: 10.1016/S0028-3908(97)00187-1  1
1997 Mellor JR, Randall AD. Frequency-dependent actions of benzodiazepines on GABAA receptors in cultured murine cerebellar granule cells. The Journal of Physiology. 503: 353-69. PMID 9306278 DOI: 10.1111/j.1469-7793.1997.353bh.x  1
1997 McNaughton NC, Randall AD. Electrophysiological properties of the human N-type Ca2+ channel: I. Channel gating in Ca2+, Ba2+ and Sr2+ containing solutions. Neuropharmacology. 36: 895-915. PMID 9257935 DOI: 10.1016/S0028-3908(97)00085-3  1
1997 Randall AD, Tsien RW. Contrasting biophysical and pharmacological properties of T-type and R-type calcium channels. Neuropharmacology. 36: 879-93. PMID 9257934 DOI: 10.1016/S0028-3908(97)00086-5  1
1997 Williamson AV, Compston DA, Randall AD. Analysis of the ion channel complement of the rat oligodendrocyte progenitor in a commonly studied in vitro preparation. The European Journal of Neuroscience. 9: 706-20. PMID 9153577  1
1997 Jones A, Korpi ER, McKernan RM, Pelz R, Nusser Z, Mäkelä R, Mellor JR, Pollard S, Bahn S, Stephenson FA, Randall AD, Sieghart W, Somogyi P, Smith AJ, Wisden W. Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1350-62. PMID 9006978  1
1996 Wheeler DB, Randall A, Tsien RW. Changes in action potential duration alter reliance of excitatory synaptic transmission on multiple types of Ca2+ channels in rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2226-37. PMID 8601803  1
1995 Randall A, Tsien RW. Pharmacological dissection of multiple types of Ca2+ channel currents in rat cerebellar granule neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 2995-3012. PMID 7722641  1
1995 Wheeler DB, Randall A, Sather WA, Tsien RW. Neuronal calcium channels encoded by the alpha 1A subunit and their contribution to excitatory synaptic transmission in the CNS. Progress in Brain Research. 105: 65-78. PMID 7568898  1
1994 Wheeler DB, Tsien RW, Randall A. Response. Science (New York, N.Y.). 266: 830-1. PMID 17730402 DOI: 10.1126/science.266.5186.830  1
1994 Wheeler DB, Sather WA, Randall A, Tsien RW. Distinctive properties of a neuronal calcium channel and its contribution to excitatory synaptic transmission in the central nervous system. Advances in Second Messenger and Phosphoprotein Research. 29: 155-71. PMID 7848709  1
1994 Clark KA, Randall AD, Collingridge GL. A comparison of paired-pulsed facilitation of AMPA and NMDA receptor-mediated excitatory postsynaptic currents in the hippocampus. Experimental Brain Research. 101: 272-8. PMID 7843313 DOI: 10.1007/BF00228747  1
1994 Wheeler DB, Randall A, Tsien RW. Roles of N-type and Q-type Ca2+ channels in supporting hippocampal synaptic transmission. Science (New York, N.Y.). 264: 107-11. PMID 7832825  1
1993 Ellinor PT, Zhang JF, Randall AD, Zhou M, Schwarz TL, Tsien RW, Horne WA. Functional expression of a rapidly inactivating neuronal calcium channel. Nature. 363: 455-8. PMID 8389006 DOI: 10.1038/363455a0  1
1993 Zhang JF, Randall AD, Ellinor PT, Horne WA, Sather WA, Tanabe T, Schwarz TL, Tsien RW. Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons. Neuropharmacology. 32: 1075-88. PMID 8107963 DOI: 10.1016/0028-3908(93)90003-L  1
1992 Randall AD, Collingridge GL. Amino acid receptor-mediated synaptic currents in the CA1 region of the hippocampus. Ion Channels. 3: 63-81. PMID 1330058  1
1992 Collingridge GL, Randall AD, Davies CH, Alford S. The synaptic activation of NMDA receptors and Ca2+ signalling in neurons. Ciba Foundation Symposium. 164: 162-71; discussion 1. PMID 1327677  1
1991 Shorte SL, Collingridge GL, Randall AD, Chappell JB, Schofield JG. Ammonium ions mobilize calcium from an internal pool which is insensitive to TRH and ionomycin in bovine anterior pituitary cells. Cell Calcium. 12: 301-12. PMID 1906784 DOI: 10.1016/0143-4160(91)90004-X  1
1991 Bashir ZI, Alford S, Davies SN, Randall AD, Collingridge GL. Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus. Nature. 349: 156-8. PMID 1846031 DOI: 10.1038/349156a0  1
1990 Randall AD, Schofield JG, Collingridge GL. Characterization of synaptic components in rat hippocampal slices using whole cell patch clamp techniques. Biochemical Society Transactions. 18: 430-1. PMID 2373230  1
1990 Randall AD, Schofield JG, Collingridge GL. Whole-cell patch-clamp recordings of an NMDA receptor-mediated synaptic current in rat hippocampal slices. Neuroscience Letters. 114: 191-6. PMID 1975659 DOI: 10.1016/0304-3940(90)90070-P  1
Show low-probability matches.