| Year |
Citation |
Score |
| 2023 |
Bartkowiak T, Lima SM, Hayes MJ, Mistry AM, Brockman AA, Sinnaeve J, Leelatian N, Roe CE, Mobley BC, Chotai S, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. An immunosuppressed microenvironment distinguishes lateral ventricle-contacting glioblastomas. Jci Insight. PMID 37192001 DOI: 10.1172/jci.insight.160652 |
0.318 |
|
| 2022 |
Medina S, Ihrie RA, Irish JM. Learning cell identity in immunology, neuroscience, and cancer. Seminars in Immunopathology. 1-14. PMID 36534139 DOI: 10.1007/s00281-022-00976-y |
0.323 |
|
| 2020 |
Ferrant J, Lhomme F, Le Gallou S, Irish JM, Roussel M. Circulating Myeloid Regulatory Cells: Promising Biomarkers in B-Cell Lymphomas. Frontiers in Immunology. 11: 623993. PMID 33603754 DOI: 10.3389/fimmu.2020.623993 |
0.309 |
|
| 2020 |
Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC. CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation. Jci Insight. 5. PMID 32814710 DOI: 10.1172/Jci.Insight.138729 |
0.31 |
|
| 2020 |
Leelatian N, Sinnaeve J, Mistry AM, Barone SM, Brockman AA, Diggins KE, Greenplate AR, Weaver KD, Thompson RC, Chambless LB, Mobley BC, Ihrie RA, Irish JM. Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells. Elife. 9. PMID 32573435 DOI: 10.7554/Elife.56879 |
0.436 |
|
| 2020 |
Lim SP, Costantini B, Mian SA, Perez Abellan P, Gandhi SA, Martinez Llordella M, Lozano JJ, Antunes Dos Reis R, Povoleri GAM, Mourikis TP, Abarrategi A, Ariza-McNaughton L, Heck S, Irish JM, Lombardi G, et al. Treg sensitivity to FasL and relative IL-2 deprivation drive Idiopathic Aplastic Anemia immune dysfunction. Blood. PMID 32294156 DOI: 10.1182/Blood.2019001347 |
0.303 |
|
| 2020 |
Ferrer-Font L, Mayer JU, Old S, Hermans IF, Irish J, Price KM. High-Dimensional Data Analysis Algorithms Yield Comparable Results for Mass Cytometry and Spectral Flow Cytometry Data. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 32293794 DOI: 10.1002/Cyto.A.24016 |
0.338 |
|
| 2020 |
Roe CE, Hayes MJ, Barone SM, Irish JM. Training Novices in Generation and Analysis of High-Dimensional Human Cell Phospho-Flow Cytometry Data. Current Protocols in Cytometry. 93: e71. PMID 32250555 DOI: 10.1002/Cpcy.71 |
0.422 |
|
| 2020 |
Roussel M, Lhomme F, Roe CE, Bartkowiak T, Gravelle P, Laurent C, Fest T, Irish JM. Mass cytometry defines distinct immune profile in germinal center B-cell lymphomas. Cancer Immunology, Immunotherapy : Cii. PMID 31919622 DOI: 10.1007/S00262-019-02464-Z |
0.369 |
|
| 2020 |
Beckermann K, Young K, Hongo R, Ye X, Contreras D, Barone S, Roe CE, Smith CC, Vincent BG, Irish JM, Rathmell WK, Rathmell JC. Targeting metabolic dysregulation of T cells in kidney cancer. Journal of Clinical Oncology. 38: 722-722. DOI: 10.1200/Jco.2020.38.6_Suppl.722 |
0.365 |
|
| 2020 |
Lehman JM, Staub J, Zou Y, Irish J, Massion P. Abstract 2692: Novel chemotherapy stable subpopulations are conserved across multiple small cell lung carcinoma patient derived xenograft models Tumor Biology. DOI: 10.1158/1538-7445.Am2020-2692 |
0.303 |
|
| 2019 |
Roussel M, Bartkowiak T, Irish JM. Picturing Polarized Myeloid Phagocytes and Regulatory Cells by Mass Cytometry. Methods in Molecular Biology (Clifton, N.J.). 1989: 217-226. PMID 31077108 DOI: 10.1007/978-1-4939-9454-0_14 |
0.338 |
|
| 2019 |
Huse K, Wogsland CE, Polikowsky HG, Diggins KE, Smeland EB, Myklebust JH, Irish JM. Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 30838773 DOI: 10.1002/Cyto.A.23737 |
0.395 |
|
| 2019 |
Alexander MR, Dale BL, Elijovich F, Wogsland CE, Irish JM, Madhur MS. Abstract 021: Single Cell Multiplex Mass Cytometry Reveals Differential Abundance of Specific Memory and Regulatory T Cell Populations in Human Hypertension Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.021 |
0.333 |
|
| 2019 |
Senosain M, Zou Y, Doxie DB, Balar A, Eisenberg R, Lehman JM, Irish JM, Massion PP. Abstract 4701: Single cell mass cytometry analysis distinguishes indolent from aggressive lung adenocarcinomas Cancer Research. 79: 4701-4701. DOI: 10.1158/1538-7445.Am2019-4701 |
0.379 |
|
| 2019 |
Bartkowiak T, Barone S, Greenplate A, Sinnaeve J, Leelatian N, Mistry A, Roe C, Mobley B, Chambless L, Thompson R, Weaver K, Ihrie R, Irish J. IMMU-37. SINGLE-CELL SYSTEMS NEUROIMMUNOLOGY REVEALS IMMUNOSUPPRESSIVE CORRELATES WITH VENTRICULAR STEM CELL NICHE CONTACT IN HUMAN GLIOBLASTOMA Neuro-Oncology. 21: vi127-vi127. DOI: 10.1093/Neuonc/Noz175.529 |
0.374 |
|
| 2019 |
Leelatian N, Sinnaeve J, Mistry A, Barone S, Diggins K, Greenplate A, Bartkowiak T, Roe C, Weaver K, Thompson R, Chambless L, Mobley B, Irish J, Ihrie R. COMP-11. SINGLE CELL MASS CYTOMETRY SIGNALING PROFILES AND A NOVEL COMPUTATIONAL TOOL IDENTIFY HIGH RISK GLIOBLASTOMA CELLS Neuro-Oncology. 21: vi63-vi63. DOI: 10.1093/Neuonc/Noz175.254 |
0.486 |
|
| 2018 |
Mistry AM, Greenplate AR, Ihrie RA, Irish JM. Beyond the message: advantages of snapshot proteomics with single-cell mass cytometry in solid tumors. The Febs Journal. PMID 30549207 DOI: 10.1111/Febs.14730 |
0.407 |
|
| 2018 |
Greenplate AR, McClanahan DD, Oberholtzer BK, Doxie DB, Roe CE, Diggins KE, Leelatian N, Rasmussen ML, Kelley MC, Gama V, Siska PJ, Rathmell JC, Ferrell PB, Johnson DB, Irish JM. Computational immune monitoring reveals abnormal double negative T cells present across human tumor types. Cancer Immunology Research. PMID 30413431 DOI: 10.1158/2326-6066.Cir-17-0692 |
0.404 |
|
| 2018 |
Doxie DB, Greenplate AR, Gandelman JS, Diggins KE, Roe CE, Dahlman KB, Sosman JA, Kelley MC, Irish JM. BRAF and MEK inhibitor therapy eliminates nestin expressing melanoma cells in human tumors. Pigment Cell & Melanoma Research. PMID 29778085 DOI: 10.1111/Pcmr.12712 |
0.413 |
|
| 2018 |
Diggins KE, Gandelman JS, Roe CE, Irish JM. Generating Quantitative Cell Identity Labels with Marker Enrichment Modeling (MEM). Current Protocols in Cytometry. 83: 10.21.1-10.21.28. PMID 29345329 DOI: 10.1002/Cpcy.34 |
0.328 |
|
| 2018 |
Earl DC, Ferrell PB, Leelatian N, Froese JT, Reisman BJ, Irish JM, Bachmann BO. Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics. Nature Communications. 9: 39. PMID 29295987 DOI: 10.1038/S41467-017-02470-8 |
0.413 |
|
| 2018 |
Alexander MR, Dale BL, Wogsland CE, Elijovich F, Irish JM, Madhur MS. Abstract P157: Immunophenotyping Human Hypertension Using Single Cell Mass Cytometry Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P157 |
0.302 |
|
| 2018 |
Senosain-Ortega M, Zou Y, Doxie DB, Roe CE, Lehman JM, Irish JM, Massion PP. Abstract 2180: Investigating lung adenocarcinoma tumor heterogeneity with single-cell mass cytometry Cancer Research. 78: 2180-2180. DOI: 10.1158/1538-7445.Am2018-2180 |
0.446 |
|
| 2017 |
Josefsson SE, Huse K, Kolstad A, Beiske K, Pende D, Steen CB, Inderberg EM, Lingjærde OC, Østenstad B, Smeland EB, Levy R, Irish JM, Myklebust JH. T cells expressing checkpoint receptor TIGIT are enriched in follicular lymphoma tumors and characterized by reversible suppression of T-cell receptor signaling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29217528 DOI: 10.1158/1078-0432.Ccr-17-2337 |
0.38 |
|
| 2017 |
Roussel M, Irish JM, Menard C, Lhomme F, Tarte K, Fest T. Regulatory myeloid cells: an underexplored continent in B-cell lymphomas. Cancer Immunology, Immunotherapy : Cii. PMID 28689360 DOI: 10.1007/S00262-017-2036-5 |
0.433 |
|
| 2017 |
Siska PJ, Beckermann KE, Mason FM, Andrejeva G, Greenplate AR, Sendor AB, Chiang YJ, Corona AL, Gemta LF, Vincent BG, Wang RC, Kim B, Hong J, Chen CL, Bullock TN, ... Irish JM, et al. Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma. Jci Insight. 2. PMID 28614802 DOI: 10.1172/Jci.Insight.93411 |
0.358 |
|
| 2017 |
Diggins KE, Greenplate AR, Leelatian N, Wogsland CE, Irish JM. Characterizing cell subsets using marker enrichment modeling. Nature Methods. PMID 28135256 DOI: 10.1038/Nmeth.4149 |
0.388 |
|
| 2017 |
Wogsland CE, Greenplate AR, Kolstad A, Myklebust JH, Irish JM, Huse K. Mass Cytometry of Follicular Lymphoma Tumors Reveals Intrinsic Heterogeneity in Proteins Including HLA-DR and a Deficit in Nonmalignant Plasmablast and Germinal Center B-Cell Populations. Cytometry. Part B, Clinical Cytometry. 92: 79-87. PMID 27933753 DOI: 10.1002/Cyto.B.21498 |
0.376 |
|
| 2017 |
Simmons AJ, Scurrah CR, McKinley ET, Herring CA, Irish JM, Washington MK, Coffey RJ, Lau KS. Abstract B29: Reorganization of signaling modules revealed in human colorectal cancer using single-cell mass cytometry Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-B29 |
0.39 |
|
| 2017 |
Lehman JM, Leelatian N, Harris B, Hoeksema M, Yong Z, Doxie DB, Irish JM, Massion PP. Abstract 3935: Dissecting small cell lung carcinoma heterogeneity and chemotherapy resistance with mass cytometry Cancer Research. 77: 3935-3935. DOI: 10.1158/1538-7445.Am2017-3935 |
0.463 |
|
| 2017 |
Leelatian N, Sinnaeve J, Mobley BC, Mistry AM, Liu D, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. Abstract 364: Mass cytometry of human glioblastoma characterizes more than 99 percent of cells and reveals intratumoral cell subsets defined by contrasting signaling network profiles Cancer Research. 77: 364-364. DOI: 10.1158/1538-7445.Am2017-364 |
0.495 |
|
| 2017 |
Doxie DB, Greenplate AR, Diggins KE, Maier CE, Sosman JA, Kelley MC, Irish JM. Abstract 2920: Characterizing human melanoma treatment responsein vivousing single-cell mass cytometry analysis of longitudinal tumor biopsies Cancer Research. 77: 2920-2920. DOI: 10.1158/1538-7445.Am2017-2920 |
0.347 |
|
| 2017 |
Doxie DB, Lehman JM, Zou Y, Ortega MS, Maier CE, Irish JM, Massion PP. Abstract 2911: Single cell mass cytometry analysis of human lung adenocarcinoma Cancer Research. 77: 2911-2911. DOI: 10.1158/1538-7445.Am2017-2911 |
0.304 |
|
| 2016 |
Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, Wälchli S, Green MR, Trøen G, Liestøl K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R. Distinct patterns of B-cell receptor signaling in non-Hodgkins' lymphomas identified by single cell profiling. Blood. PMID 28011673 DOI: 10.1182/Blood-2016-05-718494 |
0.451 |
|
| 2016 |
Simmons AJ, Scurrah CR, McKinley ET, Herring CA, Irish JM, Washington MK, Coffey RJ, Lau KS. Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks. Science Signaling. 9: rs11. PMID 27729552 DOI: 10.1126/Scisignal.Aah4413 |
0.455 |
|
| 2016 |
Leelatian N, Doxie DB, Greenplate AR, Mobley BC, Lehman JM, Sinnaeve J, Kauffmann RM, Werkhaven JA, Mistry AM, Weaver KD, Thompson RC, Massion PP, Hooks MA, Kelley MC, Chambless LB, ... ... Irish JM, et al. Single cell analysis of human tissues and solid tumors with mass cytometry. Cytometry. Part B, Clinical Cytometry. PMID 27598832 DOI: 10.1002/Cyto.B.21481 |
0.379 |
|
| 2016 |
Kordasti S, Costantini B, Seidl T, Perez Abellan P, Martinez Llordella M, McLornan D, Diggins KE, Kulasekararaj A, Benfatto C, Feng X, Smith A, Mian SA, Melchiotti R, de Rinaldis E, Ellis R, ... ... Irish JM, et al. Deep-phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment. Blood. PMID 27281795 DOI: 10.1182/Blood-2016-03-703702 |
0.337 |
|
| 2016 |
Greenplate AR, Johnson DB, Ferrell PB, Irish JM. Systems immune monitoring in cancer therapy. European Journal of Cancer (Oxford, England : 1990). 61: 77-84. PMID 27155446 DOI: 10.1016/J.Ejca.2016.03.085 |
0.438 |
|
| 2016 |
Ferrell PB, Diggins KE, Polikowsky HG, Mohan SR, Seegmiller AC, Irish JM. High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy. Plos One. 11: e0153207. PMID 27074138 DOI: 10.1371/Journal.Pone.0153207 |
0.406 |
|
| 2016 |
Greenplate AR, Johnson DB, Roussel M, Savona MR, Sosman JA, Puzanov I, Ferrell PB, Irish JM. Myelodysplastic Syndrome Revealed by Systems Immunology in a Melanoma Patient Undergoing Anti-PD-1 Therapy. Cancer Immunology Research. PMID 26966176 DOI: 10.1158/2326-6066.Cir-15-0213 |
0.36 |
|
| 2016 |
Chong KM, Leelatian N, Deguire SM, Brockman AA, Earl D, Ihrie RA, Irish JM, Bachmann BO, Sulikowski GA. The use of fluorescently-tagged apoptolidins in cellular uptake and response studies. The Journal of Antibiotics. PMID 26956792 DOI: 10.1038/Ja.2016.22 |
0.349 |
|
| 2016 |
Johnson DB, Estrada MV, Salgado R, Sanchez V, Doxie DB, Opalenik SR, Vilgelm AE, Feld E, Johnson AS, Greenplate AR, Sanders ME, Lovly CM, Frederick DT, Kelley MC, Richmond A, ... Irish JM, et al. Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy. Nature Communications. 7: 10582. PMID 26822383 DOI: 10.1038/Ncomms10582 |
0.301 |
|
| 2016 |
Gothberg S, Huse K, Kolstad A, Lingjærde OC, Østenstad B, Smeland E, Levy R, Irish JM, Myklebust JH. Identification of Tigit on Intra-Tumor T Cells As a New Target for Immune Checkpoint Blockade in Follicular Lymphoma Blood. 128: 917-917. DOI: 10.1182/Blood.V128.22.917.917 |
0.388 |
|
| 2016 |
Polikowsky HG, Byrne MT, Maier CE, Greenplate AR, Jagasia MH, Irish JM. Systems Immune Monitoring with Mass Cytometry Characterizes Altered Peripheral Immune Cell Environments in Patients with Chronic Graft Versus Host Disease Blood. 128: 4572-4572. DOI: 10.1182/Blood.V128.22.4572.4572 |
0.411 |
|
| 2016 |
Ferrell PB, Maier CR, Roussel M, Savona MR, Irish JM. Expression of S100A9 in Bone Marrow Cells Differentiates Refractory Cytopenia with Multilineage Dysplasia (RCMD) from Refractory Anemia with Excess Blasts (RAEB) and Acute Myeloid Leukemia (AML) Blood. 128: 4303-4303. DOI: 10.1182/Blood.V128.22.4303.4303 |
0.389 |
|
| 2016 |
Coats T, Smith Ae, Mourikis TP, Irish JM, Kordasti S, Mufti GJ. Mass Cytometry Reveals PD1 Upregulation Is an Early Step in MDS Disease Progression Blood. 128: 4296-4296. DOI: 10.1182/Blood.V128.22.4296.4296 |
0.342 |
|
| 2016 |
Simmons A, Banerjee A, McKinley E, Scurrah C, Franklin J, Gerdes M, Irish J, Coffey R, Lau K. P-165 Cytometry-Based Single Cell Analysis of Intact Epithelial Signaling Reveals MAPK Activation Divergent from TNF-α-Induced Apoptosis in Vivo Inflammatory Bowel Diseases. 22. DOI: 10.1097/01.Mib.0000480283.46656.D8 |
0.351 |
|
| 2016 |
Leelatian N, Sinnaeve J, Mobley B, Weaver K, Thompson R, Chambless L, Ihrie R, Irish J. CBIO-19. DISSECTING THE MULTICELLULAR ECOSYSTEM OF HUMAN GLIOBLASTOMA TUMORS USING SINGLE CELL MASS CYTOMETRY Neuro-Oncology. 18: vi39-vi39. DOI: 10.1093/Neuonc/Now212.157 |
0.341 |
|
| 2016 |
Jagasia MH, Basu T, Engelhardt BG, Chen H, Clark W, Waller EK, Giver C, Chen Y, Savani BN, Kassim AA, Jung DK, Polikowsky H, Benmebarek R, Heck S, Ellis R, ... ... Irish J, et al. Single Cell Mass Cytometry Identifies T-Regulatory Cell Subsets Associated with ECP Response in Chronic GVHD Biology of Blood and Marrow Transplantation. 22: S400-S401. DOI: 10.1016/J.Bbmt.2015.11.928 |
0.368 |
|
| 2015 |
Shah AT, Diggins KE, Walsh AJ, Irish JM, Skala MC. In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment. Neoplasia (New York, N.Y.). 17: 862-70. PMID 26696368 DOI: 10.1016/J.Neo.2015.11.006 |
0.313 |
|
| 2015 |
Nicholas KJ, Greenplate AR, Flaherty DK, Matlock BK, Juan JS, Smith RM, Irish JM, Kalams SA. Multiparameter analysis of stimulated human peripheral blood mononuclear cells: A comparison of mass and fluorescence cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 26599989 DOI: 10.1002/Cyto.A.22799 |
0.387 |
|
| 2015 |
Leelatian N, Diggins KE, Irish JM. Characterizing Phenotypes and Signaling Networks of Single Human Cells by Mass Cytometry. Methods in Molecular Biology (Clifton, N.J.). 1346: 99-113. PMID 26542718 DOI: 10.1007/978-1-4939-2987-0_8 |
0.446 |
|
| 2015 |
Simmons AJ, Banerjee A, McKinley ET, Scurrah CR, Herring CA, Gewin LS, Masuzaki R, Karp SJ, Franklin JL, Gerdes MJ, Irish JM, Coffey RJ, Lau KS. Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo. Molecular Systems Biology. 11: 835. PMID 26519361 DOI: 10.15252/Msb.20156282 |
0.471 |
|
| 2015 |
Polikowsky HG, Wogsland CE, Diggins KE, Huse K, Irish JM. Cutting Edge: Redox Signaling Hypersensitivity Distinguishes Human Germinal Center B Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 1364-7. PMID 26157177 DOI: 10.4049/Jimmunol.1500904 |
0.409 |
|
| 2015 |
Karr JR, Guturu H, Chen EY, Blair SL, Irish JM, Kotecha N, Covert MW. NetworkPainter: dynamic intracellular pathway animation in Cytobank. Bmc Bioinformatics. 16: 172. PMID 26003204 DOI: 10.1186/S12859-015-0602-4 |
0.676 |
|
| 2015 |
Diggins KE, Ferrell PB, Irish JM. Methods for discovery and characterization of cell subsets in high dimensional mass cytometry data. Methods (San Diego, Calif.). 82: 55-63. PMID 25979346 DOI: 10.1016/J.Ymeth.2015.05.008 |
0.416 |
|
| 2015 |
Green MR, Kihira S, Liu CL, Nair RV, Salari R, Gentles AJ, Irish J, Stehr H, Vicente-Dueñas C, Romero-Camarero I, Sanchez-Garcia I, Plevritis SK, Arber DA, Batzoglou S, Levy R, et al. Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation. Proceedings of the National Academy of Sciences of the United States of America. 112: E1116-25. PMID 25713363 DOI: 10.1073/Pnas.1501199112 |
0.353 |
|
| 2015 |
Ferrell PB, Senapedis W, Cook A, Baloglu E, Landesman Y, Irish JM, Savona MR. Dissecting Signaling Network Responses to PAK4 Allosteric Modulators (PAMs) in Cell Subsets within Primary Human Acute Myeloid Leukemia Samples Blood. 126: 3686-3686. DOI: 10.1182/Blood.V126.23.3686.3686 |
0.471 |
|
| 2015 |
Muehling L, Wogsland C, Agrawal R, Heymann PW, Irish JM, Woodfolk JA. High-Dimensional Single-Cell Monitoring of Circulating Cells in Allergic Asthmatics Infected with Rhinovirus Reveals Dynamic Flux in Diverse Immune Cells Journal of Allergy and Clinical Immunology. 135: AB382. DOI: 10.1016/J.Jaci.2014.12.1878 |
0.369 |
|
| 2014 |
Irish JM. Beyond the age of cellular discovery Nature Immunology. 15: 1095-1097. PMID 25396342 DOI: 10.1038/Ni.3034 |
0.356 |
|
| 2014 |
Pyne S, Lee SX, Wang K, Irish J, Tamayo P, Nazaire MD, Duong T, Ng SK, Hafler D, Levy R, Nolan GP, Mesirov J, McLachlan GJ. Joint modeling and registration of cell populations in cohorts of high-dimensional flow cytometric data. Plos One. 9: e100334. PMID 24983991 DOI: 10.1371/Journal.Pone.0100334 |
0.518 |
|
| 2014 |
Irish JM, Doxie DB. High-dimensional single-cell cancer biology. Current Topics in Microbiology and Immunology. 377: 1-21. PMID 24671264 DOI: 10.1007/82_2014_367 |
0.501 |
|
| 2014 |
Ferrell PB, Diggins KE, Polikowsky HG, Irish JM. Mass Cytometry of Acute Myeloid Leukemia Captures Early Therapy Response in Rare Cell Subsets Blood. 124: 2381-2381. DOI: 10.1182/Blood.V124.21.2381.2381 |
0.436 |
|
| 2014 |
Dave UP, Palma N, Wang K, Reddy NM, Ali S, Tripathi R, Greenplate A, Irish JM, Unutmaz D, Stephens PJ, Miller VA. Comprehensive Hybrid Capture-Based Genomic Profiling of T-Cell Leukemias and Lymphomas Reveals Targetable JAK1 and JAK3 Co-Existing Mutations Blood. 124: 1672-1672. DOI: 10.1182/Blood.V124.21.1672.1672 |
0.373 |
|
| 2014 |
Udyavar AR, Hoeksema M, Diggins K, Irish J, Massion PP, Quaranta V. Abstract B27: Phenotypic plasticity and heterogeneity in small cell lung cancer (SCLC): Novel molecular subtypes and potential for targeted therapy. Clinical Cancer Research. 20: B27-B27. DOI: 10.1158/1078-0432.14Aacriaslc-B27 |
0.43 |
|
| 2013 |
Myklebust JH, Irish JM, Brody J, Czerwinski DK, Houot R, Kohrt HE, Timmerman J, Said J, Green MR, Delabie J, Kolstad A, Alizadeh AA, Levy R. High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells. Blood. 121: 1367-76. PMID 23297127 DOI: 10.1182/Blood-2012-04-421826 |
0.355 |
|
| 2013 |
Green MR, Gentles AJ, Nair RV, Irish JM, Kihira S, Liu CL, Kela I, Hopmans ES, Myklebust JH, Ji H, Plevritis SK, Levy R, Alizadeh AA. Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma. Blood. 121: 1604-11. PMID 23297126 DOI: 10.1182/Blood-2012-09-457283 |
0.302 |
|
| 2013 |
Myklebust JH, Brody J, Alizadeh AA, Czerwinski DK, Kolstad A, Green MR, Houot R, Delabie J, Kohrt HE, Irish JM, Levy R. Potentiated B-Cell Antigen Receptor Signaling In Mantle Cell Lymphoma Is Associated With Overexpression Of Surface CD79B and IgM Blood. 122: 1768-1768. DOI: 10.1182/Blood.V122.21.1768.1768 |
0.438 |
|
| 2012 |
Blix ES, Irish JM, Husebekk A, Delabie J, Forfang L, Tierens AM, Myklebust JH, Kolstad A. Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma. Bmc Cancer. 12: 478. PMID 23072591 DOI: 10.1186/1471-2407-12-478 |
0.458 |
|
| 2012 |
Blix ES, Irish JM, Husebekk A, Delabie J, Tierens AM, Myklebust JH, Kolstad A. Altered BCR and CD40 signalling are associated with clinical outcome in small lymphocytic lymphoma/chronic lymphocytic leukaemia and marginal zone lymphoma patients. British Journal of Haematology. 159: 604-8. PMID 23043253 DOI: 10.1111/Bjh.12073 |
0.42 |
|
| 2010 |
Kotecha N, Krutzik PO, Irish JM. Web-based analysis and publication of flow cytometry experiments. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit10.17. PMID 20578106 DOI: 10.1002/0471142956.Cy1017S53 |
0.752 |
|
| 2010 |
Irish JM, Myklebust JH, Alizadeh AA, Houot R, Sharman JP, Czerwinski DK, Nolan GP, Levy R. B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 12747-54. PMID 20543139 DOI: 10.1073/Pnas.1002057107 |
0.624 |
|
| 2010 |
Irish JM, Czerwinski DK, Nolan GP, Levy R. Clinical Translation of a Prognostic Follicular Lymphoma Signaling Profile Blood. 116: 636-636. DOI: 10.1182/Blood.V116.21.636.636 |
0.632 |
|
| 2010 |
Myklebust JH, Irish JM, Brody J, Alizadeh AA, Czerwinski D, Houot R, Kohrt HE, Kolstad A, Levy R. NF-κB Signaling In Response to CpG Stratifies Mantle Cell Lymphoma Patient Outcome Blood. 116: 144-144. DOI: 10.1182/Blood.V116.21.144.144 |
0.466 |
|
| 2010 |
Hsu F, Irish J, Sachs K, Nolan G. Altered T Cell Antigen-specific Receptor Signaling in Tumor Infiltrating T Cells in Follicular Lymphomas Clinical Immunology. 135: S66. DOI: 10.1016/J.Clim.2010.03.202 |
0.544 |
|
| 2010 |
Krutzik PO, Bendall SC, Hale MB, Irish JM, Nolan GP. Phospho Flow Cytometry: Single-Cell Signaling Networks in Next-Generation Drug Discovery and Patient Stratification Flow Cytometry in Drug Discovery and Development. 303-334. DOI: 10.1002/9780470910085.ch15 |
0.738 |
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| 2009 |
Sachs K, Gentles AJ, Youland R, Itani S, Irish J, Nolan GP, Plevritis SK. Characterization of patient specific signaling via augmentation of Bayesian networks with disease and patient state nodes. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 6624-7. PMID 19963681 DOI: 10.1109/IEMBS.2009.5332563 |
0.492 |
|
| 2009 |
Houot R, Goldstein MJ, Kohrt HE, Myklebust JH, Alizadeh AA, Lin JT, Irish JM, Torchia JA, Kolstad A, Chen L, Levy R. Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion. Blood. 114: 3431-8. PMID 19641184 DOI: 10.1182/Blood-2009-05-223958 |
0.308 |
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| 2009 |
Hammer MM, Kotecha N, Irish JM, Nolan GP, Krutzik PO. WebFlow: a software package for high-throughput analysis of flow cytometry data. Assay and Drug Development Technologies. 7: 44-55. PMID 19187010 DOI: 10.1089/Adt.2008.174 |
0.76 |
|
| 2009 |
Myklebust JH, Irish JM, Houot R, Brody J, Czerwinski DK, Alizadeh AA, Kolstad A, Levy R. A Subpopulation of Follicular Lymphoma Tumor Infiltrating T Cells Shows Suppressed Common Gamma Chain Cytokine Signaling. Blood. 114: 759-759. DOI: 10.1182/Blood.V114.22.759.759 |
0.438 |
|
| 2009 |
Houot R, Goldstein MJ, Kohrt HE, Myklebust JH, Alizadeh AA, Lin JT, Irish JM, Torchia JA, Kolstad A, Chen L, Levy R. Therapeutic Potential of Anti-CD137 Antibody in Lymphoma. Blood. 114: 722-722. DOI: 10.1182/Blood.V114.22.722.722 |
0.328 |
|
| 2009 |
Law J, Ammon K, Zinter M, Wen J, Cook B, Irish JM, Hermiston ML. Distinct Signaling Profiles and Drug Responses Identify Subpopulations of Pediatric T-Cell Acute Lymphoblastic Leukemia and Lymphoma Patients. Blood. 114: 1595-1595. DOI: 10.1182/Blood.V114.22.1595.1595 |
0.479 |
|
| 2008 |
Kotecha N, Flores NJ, Irish JM, Simonds EF, Sakai DS, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell. 14: 335-43. PMID 18835035 DOI: 10.1016/J.Ccr.2008.08.014 |
0.781 |
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| 2008 |
Irish JM, Houot R, Myklebust JH, Czerwinski DK, Nolan GP, Levy R. Signaling Diversity in Human Lymphoma B Cells and in Tumor Infiltrating T Cells Correlates with Follicular Lymphoma Patient Clinical Outcomes Blood. 112: 377-377. DOI: 10.1182/Blood.V112.11.377.377 |
0.624 |
|
| 2007 |
Van Meter ME, Díaz-Flores E, Archard JA, Passegué E, Irish JM, Kotecha N, Nolan GP, Shannon K, Braun BS. K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells. Blood. 109: 3945-52. PMID 17192389 DOI: 10.1182/Blood-2006-09-047530 |
0.757 |
|
| 2007 |
Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT. Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53. Blood. 109: 2589-96. PMID 17105820 DOI: 10.1182/Blood-2006-02-004234 |
0.533 |
|
| 2007 |
Sharman JP, Irish J, Coffey G, Czerwinski D, Hitoshi Y, Levy R. Targeting syk kinase for the treatment of B-cell lymphoma Journal of Clinical Oncology. 25: 3600-3600. DOI: 10.1200/Jco.2007.25.18_Suppl.3600 |
0.431 |
|
| 2007 |
Sharman JP, Irish J, Hatton O, Martinez O, Levy R. Syk Kinase Inhibition by R406 Inhibits BCR Mediated B Cell Proliferation and Interferes with BCR Signal Transduction in Primary Tumor Samples. Blood. 110: 802-802. DOI: 10.1182/Blood.V110.11.802.802 |
0.414 |
|
| 2007 |
Kotecha N, Flores NJ, Irish JM, Sakaguchi D, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML. A Novel Assay for Juvenile Myelomonocytic Leukemia Based on Aberrant Signaling Networks Measured Via Phospho-Specific Flow Cytometry Reduces Diagnosis Time from Weeks to Days. Blood. 110: 546-546. DOI: 10.1182/Blood.V110.11.546.546 |
0.773 |
|
| 2007 |
Irish JM, Hsu FY, Sharman JP, Houot R, Brody JD, Czerwinski DK, Nolan GP, Levy R. A Profile of 648 Signaling Network Events Identifies Cell Subsets with Diverse, Abnormal Responses to Lymphocyte Stimuli within Follicular Lymphoma Tumors. Blood. 110: 356-356. DOI: 10.1182/Blood.V110.11.356.356 |
0.61 |
|
| 2006 |
Irish JM, Czerwinski DK, Nolan GP, Levy R. Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 177: 1581-9. PMID 16849466 DOI: 10.4049/Jimmunol.177.3.1581 |
0.6 |
|
| 2006 |
Irish JM, Czerwinski DK, Nolan GP, Levy R. Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Blood. 108: 3135-42. PMID 16835385 DOI: 10.1182/Blood-2006-02-003921 |
0.583 |
|
| 2006 |
Irish JM, Kotecha N, Nolan GP. Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nature Reviews. Cancer. 6: 146-55. PMID 16491074 DOI: 10.1038/Nrc1804 |
0.776 |
|
| 2006 |
Thurnher D, Reis PPd, Galloni NN, Freeman J, Brown D, Gilbert R, Gullane P, Irish J, Kamel-Reid S. P225 Genetic Analysis of Genes Involved in Signal Transduction Pathways in Oral Squamous Cell Carcinomas Archives of Otolaryngology-Head & Neck Surgery. 132: 909-910. DOI: 10.1001/Archotol.132.8.909-C |
0.349 |
|
| 2006 |
Machado J, Pintor dos Reis P, Galloni NN, Wang Y, Xu W, MacMillan C, Perez-Ordonez B, Gullane P, Irish J, Kamel-Reid S. P095 Investigation of the Mismatch Repair Genes hPMS1,hPMS2, and hMLH1 in Younger Patients With Oral Squamous Cell Carcinoma Archives of Otolaryngology–Head & Neck Surgery. 132: 884. DOI: 10.1001/Archotol.132.8.884-A |
0.302 |
|
| 2005 |
Irish J, Hovland R, Krutzik P, Perez O, Bruserud O, Gjertsen B, Nolan G. Potentiated phospho-protein networks in cancer cells Breast Cancer Research. 7: 1-1. DOI: 10.1186/Bcr1194 |
0.762 |
|
| 2005 |
Irish JM, Czerwinski DK, Nolan GP, Levy R. Rapid, Sustained B Cell Receptor Signaling in Lymphoma B Cells Differs from Normal Signaling in Tumor Infiltrating Nonmalignant B Cells. Blood. 106: 283-283. DOI: 10.1182/Blood.V106.11.283.283 |
0.6 |
|
| 2005 |
Van Meter ME, Diaz-Flores E, Archard JA, Kotecha N, Sabnis AJ, Irish JM, Nolan GP, Shannon KM, Braun BS. Multiparameter Flow Cytometric Analysis Reveals Aberrant Phosphorylation of a Network of Effector Molecules in Defined Populations of Kras Mutant Bone Marrow. Blood. 106: 239-239. DOI: 10.1182/Blood.V106.11.239.239 |
0.741 |
|
| 2004 |
Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, Gjertsen BT, Nolan GP. Single cell profiling of potentiated phospho-protein networks in cancer cells Cell. 118: 217-228. PMID 15260991 DOI: 10.1016/J.Cell.2004.06.028 |
0.763 |
|
| 2004 |
Krutzik PO, Irish JM, Nolan GP, Perez OD. Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications Clinical Immunology. 110: 206-221. PMID 15047199 DOI: 10.1016/J.Clim.2003.11.009 |
0.753 |
|
| 2002 |
Armstrong JS, Steinauer KK, Hornung B, Irish JM, Lecane P, Birrell GW, Peehl DM, Knox SJ. Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line Cell Death and Differentiation. 9: 252-263. PMID 11859408 DOI: 10.1038/Sj.Cdd.4400959 |
0.315 |
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