Philip Stork - Related publications

Affiliations: 
Vollum Institute Oregon Health and Science University, Portland, OR 
Area:
cAMP signaling, Rap1 signaling
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature Chemical Biology. PMID 32989297 DOI: 10.1038/s41589-020-00660-y   
2020 Mitchell K, Mikwar M, Da Fonte D, Lu C, Tao B, Peng D, Udeesha Erandani WKC, Hu W, Trudeau VL. Secretoneurin is a secretogranin-2 derived hormonal peptide in vertebrate neuroendocrine systems. General and Comparative Endocrinology. 113588. PMID 32828813 DOI: 10.1016/j.ygcen.2020.113588   
2020 Song P, Song B, Liu J, Wang X, Nan X, Wang J. Blockage of PAK1 alleviates the proliferation and invasion of NSCLC cells via inhibiting ERK and AKT signaling activity. Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. PMID 32974862 DOI: 10.1007/s12094-020-02486-5   
2020 Colella B, Colardo M, Iannone G, Contadini C, Saiz-Ladera C, Fuoco C, Barilà D, Velasco G, Segatto M, Di Bartolomeo S. mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells. Cancers. 12. PMID 32823532 DOI: 10.3390/cancers12082266   
2020 Kiyatkin A, van Alderwerelt van Rosenburgh IK, Klein DE, Lemmon MA. Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics. Science Signaling. 13. PMID 32817373 DOI: 10.1126/scisignal.aaz5267   
2020 Lacey BM, Xu Z, Chai X, Laskey J, Fradera X, Mittal P, Mishra S, Piesvaux J, Saradjian P, Shaffer L, Vassileva G, Gerdt C, Wang Y, Ferguson H, Smith DM, et al. Development of High-Throughput Assays for Evaluation of Hematopoietic Progenitor Kinase 1 Inhibitors. Slas Discovery : Advancing Life Sciences R & D. 2472555220952071. PMID 32844715 DOI: 10.1177/2472555220952071   
2020 Gillies TE, Pargett M, Silva JM, Teragawa CK, McCormick F, Albeck JG. Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway. Molecular Systems Biology. 16: e9518. PMID 33073539 DOI: 10.15252/msb.20209518   
2020 Tran T, Mitra J, Ha T, Kavran JM. Increasing kinase domain proximity promotes MST2 autophosphorylation during Hippo signaling. The Journal of Biological Chemistry. PMID 32994222 DOI: 10.1074/jbc.RA120.015723   
2020 Dai C, Shen L, Jin W, Lv B, Liu P, Wang X, Yin Y, Fu Y, Liang L, Ma Z, Zhang X, Wang Y, Xu D, Chen Z. Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway. Toxicology and Applied Pharmacology. 115273. PMID 33035574 DOI: 10.1016/j.taap.2020.115273   
2020 He Y, Wu Y, Mei B, Fang X, Cai G, Cai N, Wu Q, Huang Z, Ge C, Liang H, Zhang B, Chen X, Chu L. A small nucleolar RNA, SNORD126, promotes adipogenesis in cells and rats by activating the PI3K-AKT pathway. Journal of Cellular Physiology. PMID 32960468 DOI: 10.1002/jcp.30066   
2020 Spengler K, Zibrova D, Woods A, Langendorf CG, Scott JW, Carling D, Heller R. Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495. The Biochemical Journal. PMID 32869834 DOI: 10.1042/BCJ20200555   
2020 Pan L, De Smet I. Expanding the Mitogen-Activated Protein Kinase (MAPK) Universe: An Update on MAP4Ks. Frontiers in Plant Science. 11: 1220. PMID 32849755 DOI: 10.3389/fpls.2020.01220   
2020 Hu B, Zhang Y, Deng T, Gu J, Liu J, Yang H, Xu Y, Yan Y, Yang F, Zhang H, Jin Y, Zhou J. PDPK1 regulates autophagosome biogenesis by binding to PIK3C3. Autophagy. PMID 32876514 DOI: 10.1080/15548627.2020.1817279   
2020 Adam K, Ning J, Reina J, Hunter T. NME/NM23/NDPK and Histidine Phosphorylation. International Journal of Molecular Sciences. 21. PMID 32823988 DOI: 10.3390/ijms21165848   
2020 Mittal S, Kamath A, Joseph AM, Rajala MS. PLCγ1‑dependent invasion and migration of cells expressing NSCLC‑associated EGFR mutants. International Journal of Oncology. PMID 32945365 DOI: 10.3892/ijo.2020.5112   
2020 Zhao L, Geng T, Sun K, Su S, Zhao Y, Bao N, Pan L, Sun H, Li M. Proteomic analysis reveals the molecular mechanism of Hippophae rhamnoides polysaccharide intervention in LPS-induced inflammation of IPEC-J2 cells in piglets. International Journal of Biological Macromolecules. PMID 32888998 DOI: 10.1016/j.ijbiomac.2020.08.235   
2020 Brian BF, Guerrero CR, Freedman TS. Immunopharmacology and Quantitative Analysis of Tyrosine Kinase Signaling. Current Protocols in Immunology. 130: e104. PMID 32931655 DOI: 10.1002/cpim.104   
2020 Amraei R, Alwani T, Ho RX, Aryan Z, Wang S, Rahimi N. Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy. The Journal of Biological Chemistry. PMID 32978258 DOI: 10.1074/jbc.RA120.014790   
2020 Yang HW, Jung Y, Kim HD, Kim J. Ribosomal protein S3-derived repair domain peptides regulate UV-induced matrix metalloproteinase-1. Biochemical and Biophysical Research Communications. 530: 149-154. PMID 32828277 DOI: 10.1016/j.bbrc.2020.06.094   
2020 Liu R, Chen Y, Liu G, Li C, Song Y, Cao Z, Li W, Hu J, Lu C, Liu Y. PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers. Cell Death & Disease. 11: 797. PMID 32973135 DOI: 10.1038/s41419-020-02998-6   
2020 Shaaya M, Fauser J, Zhurikhina A, Conage-Pough JE, Huyot V, Brennan M, Flower CT, Matsche J, Khan S, Natarajan V, Rehman J, Kota P, White FM, Tsygankov D, Karginov AV. Light-Regulated allosteric switch enables temporal and subcellular control of enzyme activity. Elife. 9. PMID 32965214 DOI: 10.7554/eLife.60647   
2020 Diering S, Stathopoulou K, Goetz M, Rathjens L, Harder S, Piasecki A, Raabe J, Schulz S, Brandt M, Pflaumenbaum J, Fuchs U, Donzelli S, Sadayappan S, Nikolaev VO, Flenner F, et al. Receptor-independent modulation of cAMP-dependent protein kinase and protein phosphatase signaling in cardiac myocytes by oxidizing agents. The Journal of Biological Chemistry. PMID 32868295 DOI: 10.1074/jbc.RA120.014467   
2020 Asih PR, Prikas E, Stefanoska K, Tan ARP, Ahel HI, Ittner A. Functions of p38 MAP Kinases in the Central Nervous System. Frontiers in Molecular Neuroscience. 13: 570586. PMID 33013322 DOI: 10.3389/fnmol.2020.570586   
2020 Gonzalez-Magaldi M, McCabe JM, Cartwright HN, Sun N, Leahy DJ. Conserved Roles for Receptor Tyrosine Kinase Extracellular Regions in Regulating Receptor and Pathway Activity. The Biochemical Journal. PMID 33043983 DOI: 10.1042/BCJ20200702   
2020 Xu X, Lemmens LJM, den Hamer A, Merkx M, Ottmann C, Brunsveld L. Modular bioengineered kinase sensors scaffold protein-mediated split-luciferase complementation. Chemical Science. 11: 5532-5536. PMID 32874496 DOI: 10.1039/d0sc00074d   
2020 Zhang H, Lu S, Xu R, Tang Y, Liu J, Li C, Wei J, Yao R, Zhao X, Wei Q, Ma B. Mechanisms of estradiol-induced EGF-like factor expression and oocyte maturation via G protein-coupled estrogen receptor. Endocrinology. PMID 33068422 DOI: 10.1210/endocr/bqaa190   
2020 Huang JB, Hsu SP, Pan HY, Chen SD, Chen SF, Lin TK, Liu XP, Li JH, Chen NC, Liou CW, Hsu CY, Chuang HY, Chuang YC. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International Journal of Molecular Sciences. 21. PMID 33008083 DOI: 10.3390/ijms21197247   
2020 Liu QQ, Zeng XL, Guan YL, Lu JX, Tu K, Liu FY. Verticillin A inhibits colon cancer cell migration and invasion by targeting c-Met. Journal of Zhejiang University. Science. B. 21: 779-795. PMID 33043644 DOI: 10.1631/jzus.B2000190   
2020 Fang CY, Lai TC, Hsiao M, Chang YC. The Diverse Roles of TAO Kinases in Health and Diseases. International Journal of Molecular Sciences. 21. PMID 33050415 DOI: 10.3390/ijms21207463   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 CB Hanna, D Mudaliar, K John, CL Allen, L Sun, JE Hawkinson, Schönbrunn E, Georg GI, Jensen JT. Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis Biology of Reproduction. 103. PMID 32667031 DOI: 10.1093/biolre/ioaa097   
2020 Hanna CB, Mudaliar D, John K, Allen CL, Sun L, Hawkinson JE, Schönbrunn E, Georg GI, Jensen JT. Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis Biology of Reproduction. 103. PMID 32667031 DOI: 10.1093/biolre/ioaa097   
2020 Jeong H, Park S, Kim SY, Cho SH, Jeong MS, Kim SR, Seo JB, Kim SH, Kim KN. 1-Cinnamoyltrichilinin from Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells. International Journal of Molecular Sciences. 21. PMID 33053881 DOI: 10.3390/ijms21207506   
2020 He P, Mann-Collura O, Fling J, Edara N, Hetz R, Razzaque MS. High phosphate actively induces cytotoxicity by rewiring pro-survival and pro-apoptotic signaling networks in HEK293 and HeLa cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32892444 DOI: 10.1096/fj.202000799RR   
2020 Zhang M, Jang H, Nussinov R. Structural Features that Distinguish Inactive and Active PI3K Lipid Kinases. Journal of Molecular Biology. PMID 32918948 DOI: 10.1016/j.jmb.2020.09.002   
2020 Wang Q, Zhang Y, Zhu J, Zheng H, Chen S, Chen L, Yang HS. IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas. Signal Transduction and Targeted Therapy. 5: 153. PMID 32843616 DOI: 10.1038/s41392-020-0204-0   
2020 Huang J, Feng W, Li S, Tang H, Qin S, Li W, Gong Y, Fang Y, Liu Y, Wang S, Guo Y, Xu Z, Shen Q. Berberine Exerts Anti-cancer Activity by Modulating Adenosine Monophosphate-Activated Protein Kinase (AMPK) and the Phosphatidylinositol 3-Kinase/Protein Kinase B (PI3K/AKT) Signaling Pathways. Current Pharmaceutical Design. PMID 32988344 DOI: 10.2174/1381612826666200928155728   
2020 Hoy JJ, Salinas Parra N, Park J, Kuhn S, Iglesias-Bartolome R. Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32830375 DOI: 10.1096/fj.202001515R   
2020 Jena S, Damayanti NP, Tan J, Pratt ED, Irudayaraj JMK, Parker LL. Multiplexable fluorescence lifetime imaging (FLIM) probes for Abl and Src-family kinases. Chemical Communications (Cambridge, England). PMID 33035286 DOI: 10.1039/d0cc05030j   
2020 Lee SW, Commisso C. Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras. Biochemical and Biophysical Research Communications. PMID 32972751 DOI: 10.1016/j.bbrc.2020.09.029   
2020 Sammon D, Hohenester E, Leitinger B. Two-step release of kinase autoinhibition in discoidin domain receptor 1. Proceedings of the National Academy of Sciences of the United States of America. 117: 22051-22060. PMID 32839343 DOI: 10.1073/pnas.2007271117   
2020 Junaid M, Akter Y, Afrose SS, Tania M, Khan MA. Biological role of AKT, and regulation of AKT signaling pathway by thymoquinone: perspectives in cancer therapeutics. Mini Reviews in Medicinal Chemistry. PMID 33019927 DOI: 10.2174/1389557520666201005143818   
2020 Wu W, Stork B. The phospho-barcode of RIPK1: complementarity or redundancy? Molecular & Cellular Oncology. 7: 1776085. PMID 32944633 DOI: 10.1080/23723556.2020.1776085   
2020 Liu J, Ma X, Cooper GF, Lu X. Explicit representation of protein activity states significantly improves causal discovery of protein phosphorylation networks. Bmc Bioinformatics. 21: 379. PMID 32938361 DOI: 10.1186/s12859-020-03676-2   
2020 Cook SJ, Tucker JA, Lochhead PA. Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for…. Biochemical Society Transactions. PMID 32915196 DOI: 10.1042/BST20190338   
2020 Pakharukova N, Masoudi A, Pani B, Staus DP, Lefkowitz RJ. Allosteric activation of proto-oncogene kinase Src by GPCR-beta-arrestin complexes. The Journal of Biological Chemistry. PMID 32978252 DOI: 10.1074/jbc.RA120.015400   
2020 Melick CH, Jewell JL. Regulation of mTORC1 by Upstream Stimuli. Genes. 11. PMID 32854217 DOI: 10.3390/genes11090989   
2020 Kumar S, Agrawal S, Maity S, AlRaawi Z, Al-Ameer M. Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell Signaling. Current Drug Targets. PMID 33045958 DOI: 10.2174/1389450121999201012201926   
2020 Choi H, Roh J. LH-induced Transcriptional Regulation of Expression in Granulosa Cells Occurs via the cAMP/PKA Pathway and Requires a Putative Sp1 Binding Site. International Journal of Molecular Sciences. 21. PMID 33036290 DOI: 10.3390/ijms21197385