| Year |
Citation |
Score |
| 2015 |
Sheets MF, Fozzard HA, Hanck DA. Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels. Biophysical Journal. 109: 2277-86. PMID 26636939 DOI: 10.1016/j.bpj.2015.10.012 |
0.478 |
|
| 2013 |
Sheets MF, Chen T, Hanck DA. Outward stabilization of the voltage sensor in domain II but not domain I speeds inactivation of voltage-gated sodium channels. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1213-21. PMID 23893162 DOI: 10.1152/ajpheart.00225.2013 |
0.516 |
|
| 2013 |
Liu M, Hanck D, Dudley S. The Molecular Mechanism of Cardiac Sodium Channel Current Reduction with Metabolic Stress Heart Rhythm. 10: 1742-1743. DOI: 10.1016/j.hrthm.2013.09.017 |
0.566 |
|
| 2011 |
Fozzard HA, Sheets MF, Hanck DA. The sodium channel as a target for local anesthetic drugs. Frontiers in Pharmacology. 2: 68. PMID 22053156 DOI: 10.3389/fphar.2011.00068 |
0.453 |
|
| 2011 |
Lipkind GM, Fozzard HA, Hanck DA. A molecular model of the inner pore of the Ca channel in its open state. Channels (Austin, Tex.). 5: 482-8. PMID 22020562 DOI: 10.4161/chan.5.6.18354 |
0.55 |
|
| 2011 |
Bergson P, Lipkind G, Lee SP, Duban ME, Hanck DA. Verapamil block of T-type calcium channels. Molecular Pharmacology. 79: 411-9. PMID 21149638 DOI: 10.1124/mol.110.069492 |
0.578 |
|
| 2011 |
Sheets MF, Chen T, Hanck DA. Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel. PflüGers Archiv : European Journal of Physiology. 461: 91-7. PMID 20981437 DOI: 10.1007/s00424-010-0894-1 |
0.579 |
|
| 2011 |
Bergson P, Uebele VN, Renger JJ, Hanck DA. Novel Blockers of T-Type Calcium Channels Modify Gating Biophysical Journal. 100: 568a. DOI: 10.1016/j.bpj.2010.12.3293 |
0.474 |
|
| 2010 |
Sheets MF, Fozzard HA, Lipkind GM, Hanck DA. Sodium channel molecular conformations and antiarrhythmic drug affinity. Trends in Cardiovascular Medicine. 20: 16-21. PMID 20685573 DOI: 10.1016/j.tcm.2010.03.002 |
0.359 |
|
| 2010 |
Edgerton GB, Blumenthal KM, Hanck DA. Inhibition of the activation pathway of the T-type calcium channel Ca(V)3.1 by ProTxII. Toxicon : Official Journal of the International Society On Toxinology. 56: 624-36. PMID 20600227 DOI: 10.1016/J.Toxicon.2010.06.009 |
0.84 |
|
| 2010 |
Bergson P, Hu T, Uebele VN, Renger JJ, Hanck DA. Novel Blockers of T-type Calcium Channels Modify Gating Heart Rhythm. 7: 1714. DOI: 10.1016/j.hrthm.2010.09.035 |
0.474 |
|
| 2009 |
Hanck DA, Nikitina E, McNulty MM, Fozzard HA, Lipkind GM, Sheets MF. Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity. Circulation Research. 105: 492-9. PMID 19661462 DOI: 10.1161/Circresaha.109.198572 |
0.834 |
|
| 2009 |
Kyle JW, Berthoud VM, Kurutz J, Minogue PJ, Greenspan M, Hanck DA, Beyer EC. The N terminus of connexin37 contains an alpha-helix that is required for channel function. The Journal of Biological Chemistry. 284: 20418-27. PMID 19478091 DOI: 10.1074/jbc.M109.016907 |
0.361 |
|
| 2009 |
Bittner KC, Milescu L, Hanck DA. Kinetic Modeling of CaV3.1 Biophysical Journal. 96: 184a. DOI: 10.1016/J.Bpj.2008.12.861 |
0.835 |
|
| 2009 |
Edgerton GB, Hall E, Blumenthal KM, Hanck D. Charge-dependent And Isoform-specific Interactions Between ProTxii And T-type Calcium Channels Biophysical Journal. 96: 182a. DOI: 10.1016/J.Bpj.2008.12.852 |
0.846 |
|
| 2009 |
Edgerton GB, Campos FV, Blumenthal KM, Bezanilla F, Hanck DA. ProTxII Interacts Specifically with the Domain II Voltage Sensor of NaV1.4 Modifying Gating Without Immobilization Biophysical Journal. 96: 248a. DOI: 10.1016/J.Bpj.2008.12.1220 |
0.81 |
|
| 2008 |
Edgerton GB, Blumenthal KM, Hanck DA. Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5. Toxicon : Official Journal of the International Society On Toxinology. 52: 489-500. PMID 18657562 DOI: 10.1016/J.Toxicon.2008.06.023 |
0.832 |
|
| 2008 |
Bittner KC, Hanck DA. The relationship between single-channel and whole-cell conductance in the T-type Ca2+ channel CaV3.1. Biophysical Journal. 95: 931-41. PMID 18375519 DOI: 10.1529/Biophysj.107.128124 |
0.795 |
|
| 2007 |
Sheets MF, Hanck DA. Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels. The Journal of Physiology. 582: 317-34. PMID 17510181 DOI: 10.1113/jphysiol.2007.134262 |
0.543 |
|
| 2007 |
McNulty MM, Edgerton GB, Shah RD, Hanck DA, Fozzard HA, Lipkind GM. Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. The Journal of Physiology. 581: 741-55. PMID 17363383 DOI: 10.1113/Jphysiol.2007.130161 |
0.74 |
|
| 2007 |
Hanck DA, Sheets MF. Site-3 toxins and cardiac sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 181-93. PMID 17092528 DOI: 10.1016/j.toxicon.2006.09.017 |
0.566 |
|
| 2006 |
McNulty MM, Kyle JW, Lipkind GM, Hanck DA. An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels. Molecular Pharmacology. 70: 1514-23. PMID 16885209 DOI: 10.1124/Mol.106.027177 |
0.852 |
|
| 2006 |
Khan A, Kyle JW, Hanck DA, Lipkind GM, Fozzard HA. Isoform-dependent interaction of voltage-gated sodium channels with protons Journal of Physiology. 576: 493-501. PMID 16873405 DOI: 10.1113/jphysiol.2006.115659 |
0.51 |
|
| 2006 |
Freeze BS, McNulty MM, Hanck DA. State-dependent verapamil block of the cloned human Ca(v)3.1 T-type Ca(2+) channel. Molecular Pharmacology. 70: 718-26. PMID 16699084 DOI: 10.1124/Mol.106.023473 |
0.847 |
|
| 2006 |
Emerick MC, Stein R, Kunze R, McNulty MM, Regan MR, Hanck DA, Agnew WS. Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations. Proteins. 64: 320-42. PMID 16671074 DOI: 10.1002/Prot.20877 |
0.784 |
|
| 2006 |
Zhong X, Liu JR, Kyle JW, Hanck DA, Agnew WS. A profile of alternative RNA splicing and transcript variation of CACNA1H, a human T-channel gene candidate for idiopathic generalized epilepsies. Human Molecular Genetics. 15: 1497-512. PMID 16565161 DOI: 10.1093/hmg/ddl068 |
0.34 |
|
| 2005 |
Lam AD, Chikina MD, McNulty MM, Glaaser IW, Hanck DA. Role of Domain IV/S4 outermost arginines in gating of T-type calcium channels. Pflã¼Gers Archiv : European Journal of Physiology. 451: 349-61. PMID 16133267 DOI: 10.1007/S00424-005-1407-5 |
0.845 |
|
| 2005 |
Sheets MF, Hanck DA. Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation. The Journal of Physiology. 563: 83-93. PMID 15576449 DOI: 10.1113/jphysiol.2004.077644 |
0.477 |
|
| 2004 |
Sunami A, Tracey A, Glaaser IW, Lipkind GM, Hanck DA, Fozzard HA. Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents. The Journal of Physiology. 561: 403-13. PMID 15579536 DOI: 10.1113/jphysiol.2004.067579 |
0.567 |
|
| 2004 |
McNulty MM, Hanck DA. State-dependent mibefradil block of Na+ channels. Molecular Pharmacology. 66: 1652-61. PMID 15562257 DOI: 10.1124/Mol.66.6.1652 |
0.843 |
|
| 2004 |
Puljung MC, Berthoud VM, Beyer EC, Hanck DA. Polyvalent cations constitute the voltage gating particle in human connexin37 hemichannels. The Journal of General Physiology. 124: 587-603. PMID 15504903 DOI: 10.1085/Jgp.200409023 |
0.818 |
|
| 2004 |
Seibert AL, Liu J, Hanck DA, Blumenthal KM. Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3. Biochemistry. 43: 7082-9. PMID 15170345 DOI: 10.1021/Bi0496135 |
0.45 |
|
| 2003 |
Seibert AL, Liu J, Hanck DA, Blumenthal KM. Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity. Biochemistry. 42: 14515-21. PMID 14661964 DOI: 10.1021/Bi035291D |
0.502 |
|
| 2003 |
Sheets MF, Hanck DA. Molecular action of lidocaine on the voltage sensors of sodium channels. The Journal of General Physiology. 121: 163-75. PMID 12566542 DOI: 10.1085/jgp.20028651 |
0.575 |
|
| 2002 |
Sheets MF, Hanck DA. The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels. Biophysical Journal. 82: 3048-55. PMID 12023227 DOI: 10.1016/S0006-3495(02)75645-2 |
0.504 |
|
| 2000 |
Martin RL, Lee JH, Cribbs LL, Perez-Reyes E, Hanck DA. Mibefradil block of cloned T-type calcium channels. The Journal of Pharmacology and Experimental Therapeutics. 295: 302-8. PMID 10991994 |
0.589 |
|
| 2000 |
Martin RL, Pittendrigh B, Liu J, Reenan R, ffrench-Constant R, Hanck DA. Point mutations in domain III of a Drosophila neuronal Na channel confer resistance to allethrin. Insect Biochemistry and Molecular Biology. 30: 1051-9. PMID 10989292 DOI: 10.1016/S0965-1748(00)00080-1 |
0.454 |
|
| 2000 |
Hanck DA, Makielski JC, Sheets MF. Lidocaine alters activation gating of cardiac Na channels. PflüGers Archiv : European Journal of Physiology. 439: 814-21. PMID 10784357 DOI: 10.1007/S004249900217 |
0.658 |
|
| 2000 |
Sheets MF, Kyle JW, Hanck DA. The role of the putative inactivation lid in sodium channel gating current immobilization. The Journal of General Physiology. 115: 609-20. PMID 10779318 DOI: 10.1085/jgp.115.5.609 |
0.531 |
|
| 1999 |
Sheets MF, Kyle JW, Kallen RG, Hanck DA. The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. Biophysical Journal. 77: 747-57. PMID 10423423 DOI: 10.1016/S0006-3495(99)76929-8 |
0.642 |
|
| 1999 |
Benzinger GR, Tonkovich GS, Hanck DA. Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of persistent currents Journal of General Physiology. 113: 333-346. PMID 9925828 DOI: 10.1085/jgp.113.2.333 |
0.566 |
|
| 1999 |
Sheets MF, Hanck DA. Gating of skeletal and cardiac muscle sodium channels in mammalian cells. The Journal of Physiology. 514: 425-36. PMID 9852324 DOI: 10.1111/j.1469-7793.1999.425ae.x |
0.612 |
|
| 1998 |
Millonas MM, Hanck DA. Nonequilibrium response spectroscopy of voltage-sensitive ion channel gating Biophysical Journal. 74: 210-229. PMID 9449324 |
0.551 |
|
| 1998 |
Benzinger GR, Kyle JW, Blumenthal KM, Hanck DA. A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B Journal of Biological Chemistry. 273: 80-84. PMID 9417050 DOI: 10.1074/jbc.273.1.80 |
0.614 |
|
| 1997 |
Richard Benzinger G, Drum CL, Chen LQ, Kallen RG, Hanck DA. Differences in the binding sites of two site-3 sodium channel toxins Pflugers Archiv European Journal of Physiology. 434: 742-749. PMID 9306007 DOI: 10.1007/S004240050460 |
0.607 |
|
| 1996 |
Zeng D, Kyle JW, Martin RL, Ambler KS, Hanck D. Cardiac sodium channels expressed in a peripheral neurotumor-derived cell line, RT4-B8 American Journal of Physiology - Cell Physiology. 270. PMID 8967455 |
0.477 |
|
| 1996 |
Kelso GJ, Drum CL, Hanck DA, Blumenthal KM. Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel Biochemistry. 35: 14157-14164. PMID 8916901 DOI: 10.1021/Bi961584D |
0.548 |
|
| 1996 |
Sheets MF, Kyle JW, Krueger S, Hanck DA. Optimization of a mammalian expression system for the measurement of sodium channel gating currents. The American Journal of Physiology. 271: C1001-6. PMID 8843731 |
0.524 |
|
| 1996 |
Dias-Kadambi BL, Combs KA, Drum CL, Hanck DA, Blumenthal KM. The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B Journal of Biological Chemistry. 271: 23828-23835. PMID 8798612 DOI: 10.1074/Jbc.271.39.23828 |
0.54 |
|
| 1996 |
Fozzard HA, Hanck DA. Structure and function of voltage-dependent sodium channels: Comparison of brain II and cardiac isoforms Physiological Reviews. 76: 887-926. PMID 8757791 |
0.513 |
|
| 1996 |
Dias-Kadambi BL, Drum CL, Hanck DA, Blumenthal KM. Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel Journal of Biological Chemistry. 271: 9422-9428. PMID 8621610 DOI: 10.1074/Jbc.271.16.9422 |
0.463 |
|
| 1996 |
Kelso GJ, Drum CL, Hanck DA, Blumenthal KM. Replacement of individual residues of anthopleurin b with those native to anthopleurin A: A functional analysis Faseb Journal. 10. |
0.542 |
|
| 1995 |
Sheets MF, Hanck DA. Voltage-dependent open-state inactivation of cardiac sodium channels: gating current studies with Anthopleurin-A toxin. The Journal of General Physiology. 106: 617-40. PMID 8576700 DOI: 10.1085/jgp.106.4.617 |
0.589 |
|
| 1995 |
Hanck DA, Sheets MF. Modification of inactivation in cardiac sodium channels: ionic current studies with Anthopleurin-A toxin. The Journal of General Physiology. 106: 601-16. PMID 8576699 DOI: 10.1085/jgp.106.4.601 |
0.582 |
|
| 1995 |
Ono K, Fozzard HA, Hanck DA. A direct effect of forskolin on sodium channel bursting PflüGers Archiv European Journal of Physiology. 429: 561-569. PMID 7617447 DOI: 10.1007/BF00704162 |
0.493 |
|
| 1995 |
Khera PK, Benzinger GR, Lipkind G, Drum CL, Hanck DA, Blumenthal KM. Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination Biochemistry. 34: 8533-8541. PMID 7612595 DOI: 10.1021/bi00027a003 |
0.519 |
|
| 1995 |
Lipkind GM, Hanck DA, Fozzard HA. A structural motif for the voltage-gated potassium channel pore Proceedings of the National Academy of Sciences of the United States of America. 92: 9215-9219. PMID 7568104 DOI: 10.1073/pnas.92.20.9215 |
0.485 |
|
| 1994 |
Hanck DA, Makielski JC, Sheets MF. Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. The Journal of General Physiology. 103: 19-43. PMID 8169596 DOI: 10.1085/Jgp.103.1.19 |
0.569 |
|
| 1994 |
Ono K, Hanck DA, Fozzard HA. Protein kinase a-dependent phosphorylation modulation of cardiac sodium channel kinetics Japanese Heart Journal. 35: 125-126. |
0.333 |
|
| 1993 |
Ono K, Fozzard HA, Hanck DA. Mechanism of cAMP-dependent modulation of cardiac sodium channel current kinetics Circulation Research. 72: 807-815. PMID 8383015 |
0.568 |
|
| 1993 |
Sheets MF, Hanck DA. Modification of sodium channel inactivation by alpha-chymotrypsin in canine cardiac Purkinje cells. Journal of Cardiovascular Electrophysiology. 4: 686-94. PMID 8305988 |
0.584 |
|
| 1992 |
El-Sherif N, Fozzard HA, Hanck DA. Dose-dependent modulation of the cardiac sodium channel by sea anemone toxin ATXII Circulation Research. 70: 285-301. PMID 1346508 |
0.54 |
|
| 1992 |
Sheets MF, Hanck DA. Mechanisms of extracellular divalent and trivalent cation block of the sodium current in canine cardiac Purkinje cells. The Journal of Physiology. 454: 299-320. PMID 1335503 |
0.511 |
|
| 1992 |
Hanck DA, Sheets MF. Extracellular divalent and trivalent cation effects on sodium current kinetics in single canine cardiac Purkinje cells. The Journal of Physiology. 454: 267-98. PMID 1335501 |
0.403 |
|
| 1992 |
Hanck DA, Sheets MF. Time-dependent changes in kinetics of Na+ current in single canine cardiac Purkinje cells. The American Journal of Physiology. 262: H1197-207. PMID 1314510 |
0.471 |
|
| 1991 |
Sheets MF, Hanck DA. Atrionatriuretic peptide and calcium-conducting sodium channels. Science (New York, N.Y.). 252: 449-52. PMID 1850170 DOI: 10.1126/Science.1850170 |
0.49 |
|
| 1991 |
Makielski JC, Alpert LA, Hanck DA. Two components of use-dependent block of sodium current by lidocaine in voltage clamped cardiac Purkinje cells Journal of Molecular and Cellular Cardiology. 23: 95-102. PMID 1645416 DOI: 10.1016/0022-2828(91)90028-K |
0.444 |
|
| 1990 |
Hanck DA, Sheets MF, Fozzard HA. Gating currents associated with Na channels in canine cardiac Purkinje cells. The Journal of General Physiology. 95: 439-57. PMID 2157792 |
0.602 |
|
| 1990 |
Scanley BE, Hanck DA, Chay T, Fozzard HA. Kinetic analysis of single sodium channels from canine cardiac Purkinje cells Journal of General Physiology. 95: 411-437. PMID 2157791 |
0.555 |
|
| 1989 |
Alpert LA, Fozzard HA, Hanck DA, Makielski JC. Is there a second external lidocaine binding site on mammalian cardiac cells? American Journal of Physiology - Heart and Circulatory Physiology. 257. PMID 2546451 DOI: 10.1152/Ajpheart.1989.257.1.H79 |
0.429 |
|
| 1989 |
Makielski JC, Hanck DA, Fozzard HA. Ionic channels, arrhythmias and antiarrhythmic drugs Electrocardiology 1988: Proceedings of the Xvth International Congress On Electrocardiology. Ics830. 27-30. |
0.447 |
|
| 1988 |
Makielski JC, Undrovinas AI, Hanck DA, Sheets MF, Nesterenko VV, Alpert LA, Rosenshtraukh LV, Fozzard HA. Use-dependent block of sodium current by ethmozin in voltage-clamped internally perfused canine cardiac Purkinje cells. Journal of Molecular and Cellular Cardiology. 20: 255-65. PMID 2456399 DOI: 10.1016/S0022-2828(88)80058-0 |
0.48 |
|
| 1988 |
Sheets MF, Hanck DA, Fozzard HA. Nonlinear relation between Vmax and INa in canine cardiac Purkinje cells. Circulation Research. 63: 386-98. PMID 2456164 |
0.582 |
|
| 1987 |
Makielski JC, Sheets MF, Hanck DA, January CT, Fozzard HA. Sodium current in voltage clamped internally perfused canine cardiac Purkinje cells. Biophysical Journal. 52: 1-11. PMID 3607218 DOI: 10.1016/S0006-3495(87)83182-X |
0.431 |
|
| 1987 |
Fozzard HA, Hanck DA, Makielski JC, Scanley BE, Sheets MF. Sodium channels in cardiac Purkinje cells. Experientia. 43: 1162-8. PMID 2446909 DOI: 10.1007/Bf01945516 |
0.465 |
|
| 1987 |
Sheets MF, Scanley BE, Hanck DA, Makielski JC, Fozzard HA. Open sodium channel properties of single canine cardiac Purkinje cells. Biophysical Journal. 52: 13-22. PMID 2440490 DOI: 10.1016/S0006-3495(87)83183-1 |
0.608 |
|
| 1986 |
Fozzard HA, Friedlander IR, Hanck DA, January CT, Makielski JC, Sheets MF. Sodium currents in single cardiac Purkinje cells. Journal of the American College of Cardiology. 8: 79A-85A. PMID 2423574 DOI: 10.1016/S0735-1097(86)80033-X |
0.542 |
|
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