David E. Briles - Publications

Affiliations: 
University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Microbiology Biology

307 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang J, An H, Ding M, Liu Y, Wang S, Jin Q, Wu Q, Dong H, Guo Q, Tian X, Liu J, Zhang J, Zhu T, Li J, Shao Z, ... Briles DE, et al. Liver macrophages and sinusoidal endothelial cells execute vaccine-elicited capture of invasive bacteria. Science Translational Medicine. 15: eade0054. PMID 38117903 DOI: 10.1126/scitranslmed.ade0054  0.315
2022 Lane JR, Tata M, Briles DE, Orihuela CJ. A Jack of All Trades: The Role of Pneumococcal Surface Protein A in the Pathogenesis of . Frontiers in Cellular and Infection Microbiology. 12: 826264. PMID 35186799 DOI: 10.3389/fcimb.2022.826264  0.457
2021 Park SS, Gonzalez-Juarbe N, Riegler AN, Im H, Hale Y, Platt MP, Croney C, Briles DE, Orihuela CJ. Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza. Cell Reports. 35: 109267. PMID 34133917 DOI: 10.1016/j.celrep.2021.109267  0.796
2021 Nakahashi-Ouchida R, Uchida Y, Yuki Y, Katakai Y, Yamanoue T, Ogawa H, Munesue Y, Nakano N, Hanari K, Miyazaki T, Saito Y, Umemoto S, Sawada SI, Mukerji R, Briles DE, et al. A nanogel-based trivalent PspA nasal vaccine protects macaques from intratracheal challenge with pneumococci. Vaccine. PMID 34016473 DOI: 10.1016/j.vaccine.2021.04.069  0.409
2021 Park SS, Gonzalez-Juarbe N, Martínez E, Hale JY, Lin YH, Huffines JT, Kruckow KL, Briles DE, Orihuela CJ. Streptococcus pneumoniae Binds to Host Lactate Dehydrogenase via PspA and PspC To Enhance Virulence. Mbio. 12. PMID 33947761 DOI: 10.1128/mBio.00673-21  0.397
2021 Yuki Y, Uchida Y, Sawada SI, Nakahashi-Ouchida R, Sugiura K, Mori H, Yamanoue T, Machita T, Honma A, Kurokawa S, Mukerji R, Briles DE, Akiyoshi K, Kiyono H. Characterization and Specification of a Trivalent Protein-Based Pneumococcal Vaccine Formulation Using an Adjuvant-Free Nanogel Nasal Delivery System. Molecular Pharmaceutics. PMID 33621107 DOI: 10.1021/acs.molpharmaceut.0c01003  0.402
2021 Takeda S, Kono M, Sugita G, Arai J, Briles DE, Hotomi M. Pneumococcal capsular phase shift is associated with invasion into cell-to-cell junctions and is inhibited by macrolides. Microbial Pathogenesis. 104787. PMID 33609643 DOI: 10.1016/j.micpath.2021.104787  0.302
2020 Mukerji R, Briles DE. New Strategy Is Needed to Prevent Pneumococcal Meningitis. The Pediatric Infectious Disease Journal. PMID 32032170 DOI: 10.1097/Inf.0000000000002581  0.475
2020 Briles DE, Paton JC, Mukerji R, Swiatlo E, Crain MJ. Pneumococcal Vaccines. Microbiology Spectrum. 7. PMID 31858954 DOI: 10.1128/microbiolspec.gpp3-0028-2018  0.404
2019 Keech CA, Morrison R, Anderson P, Tate A, Flores J, Goldblatt D, Briles D, Hural J, Malley R, Alderson MR. A Phase 1 Randomized, Placebo-controlled, Observer-blinded Trial to Evaluate the Safety and Immunogenicity of Inactivated Streptococcus pneumoniae Whole-cell Vaccine in Adults. The Pediatric Infectious Disease Journal. PMID 31895881 DOI: 10.1097/Inf.0000000000002567  0.491
2019 Genschmer KR, Vadesilho CFM, McDaniel LS, Park SS, Hale Y, Miyaji EN, Briles DE. The Modified Surface Killing Assay Distinguishes between Protective and Nonprotective Antibodies to PspA. Msphere. 4. PMID 31826968 DOI: 10.1128/mSphere.00589-19  0.801
2019 Martinez PJ, Farhan A, Mustafa M, Javaid N, Darkoh C, Garrido-Sanabria E, Fisher-Hoch SP, Briles DE, Kantarci A, Mirza S. PspA facilitates evasion of pneumococci from bactericidal activity of neutrophil extracellular traps (NETs). Microbial Pathogenesis. 103653. PMID 31398527 DOI: 10.1016/J.Micpath.2019.103653  0.666
2018 Mukerji R, Hendrickson C, Genschmer KR, Park SS, Bouchet V, Goldstein R, Lefkowitz EJ, Briles DE. The diversity of the proline-rich domain of pneumococcal surface protein A (PspA): Potential relevance to a broad-spectrum vaccine. Vaccine. PMID 30293761 DOI: 10.1016/J.Vaccine.2018.08.045  0.8
2018 Dennis EA, Coats MT, Griffin S, Pang B, Briles DE, Crain MJ, Swords WE. Hyperencapsulated Mucoid Pneumococcal Isolates from Patients with Cystic Fibrosis Have Increased Biofilm Density and Persistence In vivo. Pathogens and Disease. PMID 30265307 DOI: 10.1093/Femspd/Fty073  0.786
2018 Totten AH, Xiao L, Luo D, Briles D, Hale JY, Crabb DM, Schoeb TR, Alishlash AS, Waites KB, Atkinson TP. Allergic Airway Sensitization Impairs Anti-Bacterial IgG Antibody Responses During Bacterial Respiratory Infections. The Journal of Allergy and Clinical Immunology. PMID 30092287 DOI: 10.1016/J.Jaci.2018.07.021  0.446
2018 Larson-Casey JL, Gu L, Jackson PL, Briles DE, Hale JY, Blalock JE, Wells JM, Deshane JS, Wang Y, Davis D, Antony VB, Massicano AVF, Lapi SE, Carter AB. Macrophage Rac2 Is Required to Reduce the Severity of Cigarette Smoke-induced Pneumonia. American Journal of Respiratory and Critical Care Medicine. PMID 29897791 DOI: 10.1164/Rccm.201712-2388Oc  0.568
2018 Wang Y, Wen Z, Pan X, Briles DE, He Y, Zhang JR. Novel Immunoprotective Proteins of Identified by Opsonophagocytosis Killing Screen. Infection and Immunity. PMID 29891544 DOI: 10.1128/Iai.00423-18  0.515
2017 Kim GL, Luong TT, Park SS, Lee S, Ha JA, Nguyen CT, Ahn JH, Park KT, Paik MJ, Suhkneung-Pyo, Briles DE, Rhee DK. Inhibition of Autolysis by Lipase LipA in Streptococcus pneumoniae Sepsis. Molecules and Cells. 40: 935-944. PMID 29281779 DOI: 10.14348/Molcells.2017.0201  0.504
2017 Nagano H, Kawabata M, Sugita G, Tsuruhara A, Ohori J, Jimura T, Miyashita K, Kurono Y, Tomonaga K, Briles DE, Fujihashi K. Transcutaneous immunization with pneumococcal surface protein A in mice. The Laryngoscope. PMID 29226330 DOI: 10.1002/Lary.26971  0.542
2017 Schachern PA, Kwon G, Briles DE, Ferrieri P, Juhn S, Cureoglu S, Paparella MM, Tsuprun V. Neutrophil Extracellular Traps and Fibrin in Otitis Media: Analysis of Human and Chinchilla Temporal Bones. Jama Otolaryngology-- Head & Neck Surgery. PMID 28796849 DOI: 10.1001/Jamaoto.2017.1320  0.394
2017 Kataoka K, Fukuyama Y, Briles DE, Miyake T, Fujihashi K. Dendritic cell-targeting DNA-based nasal adjuvants for protective mucosal immunity to Streptococcus pneumoniae. Microbiology and Immunology. PMID 28463465 DOI: 10.1111/1348-0421.12487  0.515
2016 Kim GL, Choi SY, Seon SH, Lee S, Park SS, Song JY, Briles DE, Rhee DK. Pneumococcal pep27 mutant immunization stimulates cytokine secretion and confers long-term immunity with a wide range of protection, including against non-typeable strains. Vaccine. PMID 27865564 DOI: 10.1016/J.Vaccine.2016.10.071  0.525
2016 Mirza S, Benjamin WH, Coan PA, Hwang SA, Winslett AK, Yother J, Hollingshead SK, Fujihashi K, Briles DE. The effects of differences in pspA alleles and capsular types on the resistance of Streptococcus pneumoniae to killing by apolactoferrin. Microbial Pathogenesis. PMID 27569531 DOI: 10.1016/J.Micpath.2016.08.029  0.771
2016 Hatcher BL, Hale JY, Briles DE. Free Sialic Acid: A Signal That Promotes Streptococcus pneumoniae Invasion of Nasal Tissue and Nonhematogenous Invasion of the Central Nervous System. Infection and Immunity. PMID 27354445 DOI: 10.1128/Iai.01514-15  0.423
2016 Walker MM, Novak L, Widener R, Grubbs JA, King J, Hale JY, Ochs MM, Myers LE, Briles DE, Deshane J. PcpA Promotes Higher Levels of Infection and Modulates Recruitment of Myeloid-Derived Suppressor Cells during Pneumococcal Pneumonia. Journal of Immunology (Baltimore, Md. : 1950). PMID 26829988 DOI: 10.4049/Jimmunol.1402518  0.482
2016 Hotomi M, Yuasa J, Briles DE, Yamanaka N. Pneumolysin plays a key role at the initial step of establishing pneumococcal nasal colonization. Folia Microbiologica. PMID 26803756 DOI: 10.1007/S12223-016-0445-Z  0.425
2015 Kim JY, Paton JC, Briles DE, Rhee DK, Pyo S. Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia. Oncotarget. PMID 26683708 DOI: 10.18632/Oncotarget.6592  0.397
2015 Dennis EA, Coats MT, Griffin SE, Hale JY, Novak L, Briles DE, Crain MJ. The Effects of CFTR and Mucoid Phenotype on Susceptibility and Innate Immune Responses in a Mouse Model of Pneumococcal Lung Disease. Plos One. 10: e0140335. PMID 26469863 DOI: 10.1371/Journal.Pone.0140335  0.797
2015 Chen A, Mann B, Gao G, Heath R, King J, Maissoneuve J, Alderson M, Tate A, Hollingshead SK, Tweten RK, Briles DE, Tuomanen EI, Paton JC. Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection. Clinical and Vaccine Immunology : Cvi. 22: 1079-89. PMID 26245351 DOI: 10.1128/Cvi.00293-15  0.52
2015 Fukuyama Y, Ikeda Y, Ohori J, Sugita G, Aso K, Fujihashi K, Briles DE, McGhee JR, Fujihashi K. A molecular mucosal adjuvant to enhance immunity against pneumococcal infection in the elderly. Immune Network. 15: 9-15. PMID 25713504 DOI: 10.4110/In.2015.15.1.9  0.542
2015 Fukuyama Y, Yuki Y, Katakai Y, Harada N, Takahashi H, Takeda S, Mejima M, Joo S, Kurokawa S, Sawada S, Shibata H, Park EJ, Fujihashi K, Briles DE, Yasutomi Y, et al. Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques. Mucosal Immunology. PMID 25669148 DOI: 10.1038/Mi.2015.5  0.5
2015 Park SS, Kwon HY, Tran TD, Choi MH, Jung SH, Lee S, Briles DE, Rhee DK. ClpL is a chaperone without auxiliary factors. The Febs Journal. 282: 1352-67. PMID 25662392 DOI: 10.1111/Febs.13228  0.379
2015 Kothari N, Kothari S, Choi YJ, Dey A, Briles DE, Rhee DK, Carbis R. A bivalent conjugate vaccine containing PspA families 1 and 2 has the potential to protect against a wide range of Streptococcus pneumoniae strains and Salmonella Typhi. Vaccine. 33: 783-8. PMID 25545593 DOI: 10.1016/J.Vaccine.2014.12.032  0.512
2015 Miyaji EN, Vadesilho CF, Oliveira ML, Zelanis A, Briles DE, Ho PL. Evaluation of a vaccine formulation against Streptococcus pneumoniae based on choline-binding proteins. Clinical and Vaccine Immunology : Cvi. 22: 213-20. PMID 25520146 DOI: 10.1128/Cvi.00692-14  0.553
2015 Luong TT, Kim EH, Bak JP, Nguyen CT, Choi S, Briles DE, Pyo S, Rhee DK. Ethanol-induced alcohol dehydrogenase E (AdhE) potentiates pneumolysin in Streptococcus pneumoniae. Infection and Immunity. 83: 108-19. PMID 25312953 DOI: 10.1128/Iai.02434-14  0.432
2015 Kothari N, Kothari S, Choi YJ, Dey A, Briles DE, Rhee DK, Carbis R. A bivalent conjugate vaccine containing PspA families 1 and 2 has the potential to protect against a wide range of Streptococcus pneumoniae strains and Salmonella Typhi Vaccine. 33: 783-788. DOI: 10.1016/j.vaccine.2014.12.032  0.414
2014 Wade KR, Hotze EM, Briles DE, Tweten RK. Mouse, but not human, ApoB-100 lipoprotein cholesterol is a potent innate inhibitor of Streptococcus pneumoniae pneumolysin. Plos Pathogens. 10: e1004353. PMID 25188225 DOI: 10.1371/Journal.Ppat.1004353  0.377
2014 Kothari N, Genschmer KR, Kothari S, Kim JA, Briles DE, Rhee DK, Carbis R. Preparation and testing of a Vi conjugate vaccine using pneumococcal surface protein A (PspA) from Streptococcus pneumoniae as the carrier protein. Vaccine. 32: 5755-60. PMID 25171842 DOI: 10.1016/J.Vaccine.2014.08.041  0.797
2014 Piao Z, Akeda Y, Takeuchi D, Ishii KJ, Ubukata K, Briles DE, Tomono K, Oishi K. Protective properties of a fusion pneumococcal surface protein A (PspA) vaccine against pneumococcal challenge by five different PspA clades in mice. Vaccine. 32: 5607-13. PMID 25132335 DOI: 10.1016/J.Vaccine.2014.07.108  0.579
2014 Schachern PA, Tsuprun V, Ferrieri P, Briles DE, Goetz S, Cureoglu S, Paparella MM, Juhn S. Pneumococcal PspA and PspC proteins: potential vaccine candidates for experimental otitis media. International Journal of Pediatric Otorhinolaryngology. 78: 1517-21. PMID 25015773 DOI: 10.1016/J.Ijporl.2014.06.024  0.519
2014 Vadesilho CF, Ferreira DM, Gordon SB, Briles DE, Moreno AT, Oliveira ML, Ho PL, Miyaji EN. Mapping of epitopes recognized by antibodies induced by immunization of mice with PspA and PspC. Clinical and Vaccine Immunology : Cvi. 21: 940-8. PMID 24807052 DOI: 10.1128/Cvi.00239-14  0.559
2014 Bischof A, Brumshagen C, Ding N, Kirchhof G, Briles DE, Gessner JE, Welte T, Mack M, Maus UA. Basophil expansion protects against invasive pneumococcal disease in mice. The Journal of Infectious Diseases. 210: 14-24. PMID 24470504 DOI: 10.1093/Infdis/Jiu056  0.494
2013 Genschmer KR, Accavitti-Loper MA, Briles DE. A modified surface killing assay (MSKA) as a functional in vitro assay for identifying protective antibodies against pneumococcal surface protein A (PspA). Vaccine. 32: 39-47. PMID 24211169 DOI: 10.1016/J.Vaccine.2013.10.080  0.826
2013 Schachern PA, Tsuprun V, Goetz S, Cureoglu S, Juhn SK, Briles DE, Paparella MM, Ferrieri P. Viability and virulence of pneumolysin, pneumococcal surface protein A, and pneumolysin/pneumococcal surface protein A mutants in the ear. Jama Otolaryngology-- Head & Neck Surgery. 139: 937-43. PMID 24051749 DOI: 10.1001/Jamaoto.2013.4104  0.437
2013 Croney CM, Nahm MH, Juhn SK, Briles DE, Crain MJ. Invasive and noninvasive Streptococcus pneumoniae capsule and surface protein diversity following the use of a conjugate vaccine. Clinical and Vaccine Immunology : Cvi. 20: 1711-8. PMID 24006139 DOI: 10.1128/Cvi.00381-13  0.816
2013 Daniels CC, Kim KH, Burton RL, Mirza S, Walker M, King J, Hale Y, Coan P, Rhee DK, Nahm MH, Briles DE. Modified opsonization, phagocytosis, and killing assays to measure potentially protective antibodies against pneumococcal surface protein A. Clinical and Vaccine Immunology : Cvi. 20: 1549-58. PMID 23925886 DOI: 10.1128/Cvi.00371-13  0.813
2013 Darrieux M, Goulart C, Briles D, Leite LC. Current status and perspectives on protein-based pneumococcal vaccines. Critical Reviews in Microbiology. 41: 190-200. PMID 23895377 DOI: 10.3109/1040841X.2013.813902  0.475
2013 Haughney SL, Petersen LK, Schoofs AD, Ramer-Tait AE, King JD, Briles DE, Wannemuehler MJ, Narasimhan B. Retention of structure, antigenicity, and biological function of pneumococcal surface protein A (PspA) released from polyanhydride nanoparticles. Acta Biomaterialia. 9: 8262-71. PMID 23774257 DOI: 10.1016/J.Actbio.2013.06.006  0.488
2013 Zhao H, Jung JA, Briles DE, Kita H, Tsigrelis C, Juhn YJ. Asthma and antibodies to pneumococcal virulence proteins. Infection. 41: 927-34. PMID 23749296 DOI: 10.1007/S15010-013-0482-3  0.463
2013 Choi SY, Tran TD, Briles DE, Rhee DK. Inactivated pep27 mutant as an effective mucosal vaccine against a secondary lethal pneumococcal challenge in mice. Clinical and Experimental Vaccine Research. 2: 58-65. PMID 23596592 DOI: 10.7774/Cevr.2013.2.1.58  0.547
2013 Vale AM, Kapoor P, Skibinski GA, Elgavish A, Mahmoud TI, Zemlin C, Zemlin M, Burrows PD, Nobrega A, Kearney JF, Briles DE, Schroeder HW. The link between antibodies to OxLDL and natural protection against pneumococci depends on D(H) gene conservation. The Journal of Experimental Medicine. 210: 875-90. PMID 23589567 DOI: 10.1084/Jem.20121861  0.471
2013 Hotomi M, Togawa A, Kono M, Ikeda Y, Takei S, Hollingshead SK, Briles DE, Suzuki K, Yamanaka N. PspA family distribution, antimicrobial resistance and serotype of Streptococcus pneumoniae isolated from upper respiratory tract infections in Japan. Plos One. 8: e58124. PMID 23483982 DOI: 10.1371/Journal.Pone.0058124  0.506
2013 Kong IG, Sato A, Yuki Y, Nochi T, Takahashi H, Sawada S, Mejima M, Kurokawa S, Okada K, Sato S, Briles DE, Kunisawa J, Inoue Y, Yamamoto M, Akiyoshi K, et al. Nanogel-based PspA intranasal vaccine prevents invasive disease and nasal colonization by Streptococcus pneumoniae. Infection and Immunity. 81: 1625-34. PMID 23460513 DOI: 10.1128/Iai.00240-13  0.519
2012 Mukerji R, Mirza S, Roche AM, Widener RW, Croney CM, Rhee DK, Weiser JN, Szalai AJ, Briles DE. Pneumococcal surface protein A inhibits complement deposition on the pneumococcal surface by competing with the binding of C-reactive protein to cell-surface phosphocholine. Journal of Immunology (Baltimore, Md. : 1950). 189: 5327-35. PMID 23105137 DOI: 10.4049/Jimmunol.1201967  0.794
2012 Ren B, Li J, Genschmer K, Hollingshead SK, Briles DE. The absence of PspA or presence of antibody to PspA facilitates the complement-dependent phagocytosis of pneumococci in vitro. Clinical and Vaccine Immunology : Cvi. 19: 1574-82. PMID 22855389 DOI: 10.1128/Cvi.00393-12  0.803
2012 Croney CM, Coats MT, Nahm MH, Briles DE, Crain MJ. PspA family distribution, unlike capsular serotype, remains unaltered following introduction of the heptavalent pneumococcal conjugate vaccine. Clinical and Vaccine Immunology : Cvi. 19: 891-6. PMID 22539473 DOI: 10.1128/Cvi.05671-11  0.787
2012 Park IH, Kim KH, Andrade AL, Briles DE, McDaniel LS, Nahm MH. Nontypeable pneumococci can be divided into multiple cps types, including one type expressing the novel gene pspK. Mbio. 3. PMID 22532557 DOI: 10.1128/Mbio.00035-12  0.495
2012 Weber M, Lambeck S, Ding N, Henken S, Kohl M, Deigner HP, Enot DP, Igwe EI, Frappart L, Kiehntopf M, Claus RA, Kamradt T, Weih D, Vodovotz Y, Briles DE, et al. Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2424-36. PMID 22415311 DOI: 10.1096/Fj.11-191957  0.451
2012 Bieghs V, van Gorp PJ, Walenbergh SM, Gijbels MJ, Verheyen F, Buurman WA, Briles DE, Hofker MH, Binder CJ, Shiri-Sverdlov R. Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice. Hepatology (Baltimore, Md.). 56: 894-903. PMID 22334337 DOI: 10.1002/Hep.25660  0.445
2012 Singh R, Singh S, Briles DE, Taub DD, Hollingshead SK, Lillard JW. CCL5-independent helper T lymphocyte responses to immuno-dominant pneumococcal surface protein A epitopes. Vaccine. 30: 1181-90. PMID 22178100 DOI: 10.1016/J.Vaccine.2011.12.020  0.487
2012 Kim EH, Choi SY, Kwon MK, Tran TD, Park SS, Lee KJ, Bae SM, Briles DE, Rhee DK. Streptococcus pneumoniae pep27 mutant as a live vaccine for serotype-independent protection in mice. Vaccine. 30: 2008-19. PMID 22154770 DOI: 10.1016/J.Vaccine.2011.11.073  0.549
2011 Kono M, Hotomi M, Hollingshead SK, Briles DE, Yamanaka N. Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring. Plos One. 6: e27102. PMID 22073127 DOI: 10.1371/Journal.Pone.0027102  0.516
2011 Tran TD, Kwon HY, Kim EH, Kim KW, Briles DE, Pyo S, Rhee DK. Heat-shock protein ClpL/HSP100 increases penicillin tolerance in Streptococcus pneumoniae. Advances in Oto-Rhino-Laryngology. 72: 126-8. PMID 21865709 DOI: 10.1159/000324658  0.393
2011 Hotomi M, Kono M, Hollingshead SK, Briles DE, Yamanaka N. Protection of pneumococcal infection by maternal intranasal immunization with pneumococcal surface protein A. Advances in Oto-Rhino-Laryngology. 72: 121-5. PMID 21865708 DOI: 10.1159/000324656  0.522
2011 Briles DE, Miyaji E, Fukuyama Y, Ferreira DM, Fujihashi K. Elicitation of mucosal immunity by proteins of Streptococcus pneumoniae. Advances in Oto-Rhino-Laryngology. 72: 25-7. PMID 21865682 DOI: 10.1159/000324589  0.499
2011 Kataoka K, Fujihashi K, Oma K, Fukuyama Y, Hollingshead SK, Sekine S, Kawabata S, Ito HO, Briles DE, Oishi K. The nasal dendritic cell-targeting Flt3 ligand as a safe adjuvant elicits effective protection against fatal pneumococcal pneumonia. Infection and Immunity. 79: 2819-28. PMID 21536790 DOI: 10.1128/Iai.01360-10  0.518
2011 Tran TD, Kwon HY, Kim EH, Kim KW, Briles DE, Pyo S, Rhee DK. Decrease in penicillin susceptibility due to heat shock protein ClpL in Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy. 55: 2714-28. PMID 21422206 DOI: 10.1128/Aac.01383-10  0.445
2011 Mirza S, Wilson L, Benjamin WH, Novak J, Barnes S, Hollingshead SK, Briles DE. Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin. Infection and Immunity. 79: 2440-50. PMID 21422179 DOI: 10.1128/Iai.00489-10  0.599
2011 Coats MT, Murphy T, Paton JC, Gray B, Briles DE. Exposure of Thomsen-Friedenreich antigen in Streptococcus pneumoniae infection is dependent on pneumococcal neuraminidase A. Microbial Pathogenesis. 50: 343-9. PMID 21377521 DOI: 10.1016/J.Micpath.2011.02.010  0.798
2011 Arai J, Hotomi M, Hollingshead SK, Ueno Y, Briles DE, Yamanaka N. Streptococcus pneumoniae isolates from middle ear fluid and nasopharynx of children with acute otitis media exhibit phase variation. Journal of Clinical Microbiology. 49: 1646-9. PMID 21346044 DOI: 10.1128/Jcm.01990-10  0.374
2011 Fukuyama Y, King JD, Kataoka K, Kobayashi R, Gilbert RS, Hollingshead SK, Briles DE, Fujihashi K. A combination of Flt3 ligand cDNA and CpG oligodeoxynucleotide as nasal adjuvant elicits protective secretory-IgA immunity to Streptococcus pneumoniae in aged mice. Journal of Immunology (Baltimore, Md. : 1950). 186: 2454-61. PMID 21242514 DOI: 10.4049/Jimmunol.1002837  0.487
2011 Gwinn WM, Kirwan SM, Wang SH, Ashcraft KA, Sparks NL, Doil CR, Tlusty TG, Casey LS, Hollingshead SK, Briles DE, Dondero RS, Hickey AJ, Foster WM, Staats HF. Erratum to “Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1” [Vaccine 28 (42) (2010) 6901–6914] Vaccine. 29: 2821. DOI: 10.1016/J.Vaccine.2011.01.096  0.394
2010 Schachern PA, Tsuprun V, Cureoglu S, Ferrieri PA, Briles DE, Paparella MM, Juhn SK. Effect of apolactoferrin on experimental pneumococcal otitis media. Archives of Otolaryngology--Head & Neck Surgery. 136: 1127-31. PMID 21079169 DOI: 10.1001/Archoto.2010.192  0.358
2010 Gwinn WM, Kirwan SM, Wang SH, Ashcraft KA, Sparks NL, Doil CR, Tlusty TG, Casey LS, Hollingshead SK, Briles DE, Dondero RS, Hickey AJ, Foster WM, Staats HF. Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1. Vaccine. 28: 6901-14. PMID 20723629 DOI: 10.1016/J.Vaccine.2010.08.006  0.495
2010 Fukuyama Y, King JD, Kataoka K, Kobayashi R, Gilbert RS, Oishi K, Hollingshead SK, Briles DE, Fujihashi K. Secretory-IgA antibodies play an important role in the immunity to Streptococcus pneumoniae. Journal of Immunology (Baltimore, Md. : 1950). 185: 1755-62. PMID 20585031 DOI: 10.4049/Jimmunol.1000831  0.558
2010 Li J, Wang JP, Ghiran I, Cerny A, Szalai AJ, Briles DE, Finberg RW. Complement receptor 1 expression on mouse erythrocytes mediates clearance of Streptococcus pneumoniae by immune adherence. Infection and Immunity. 78: 3129-35. PMID 20439480 DOI: 10.1128/Iai.01263-09  0.449
2010 Herbold W, Maus R, Hahn I, Ding N, Srivastava M, Christman JW, Mack M, Reutershan J, Briles DE, Paton JC, Winter C, Welte T, Maus UA. Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection. Infection and Immunity. 78: 2620-30. PMID 20368349 DOI: 10.1128/Iai.01169-09  0.462
2010 Ferreira DM, Oliveira ML, Moreno AT, Ho PL, Briles DE, Miyaji EN. Protection against nasal colonization with Streptococcus pneumoniae by parenteral immunization with a DNA vaccine encoding PspA (Pneumococcal surface protein A). Microbial Pathogenesis. 48: 205-13. PMID 20206678 DOI: 10.1016/J.Micpath.2010.02.009  0.551
2010 Singh R, Singh S, Sharma PK, Singh UP, Briles DE, Hollingshead SK, Lillard JW. Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A. Plos One. 5: e9432. PMID 20195541 DOI: 10.1371/Journal.Pone.0009432  0.459
2010 Daniels CC, Coan P, King J, Hale J, Benton KA, Briles DE, Hollingshead SK. The proline-rich region of pneumococcal surface proteins A and C contains surface-accessible epitopes common to all pneumococci and elicits antibody-mediated protection against sepsis. Infection and Immunity. 78: 2163-72. PMID 20194601 DOI: 10.1128/Iai.01199-09  0.771
2010 Diavatopoulos DA, Short KR, Price JT, Wilksch JJ, Brown LE, Briles DE, Strugnell RA, Wijburg OL. Influenza A virus facilitates Streptococcus pneumoniae transmission and disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1789-98. PMID 20097876 DOI: 10.1096/Fj.09-146779  0.49
2010 Henken S, Bohling J, Martens-Lobenhoffer J, Paton JC, Ogunniyi AD, Briles DE, Salisbury VC, Wedekind D, Bode-Böger SM, Welsh T, Bange FC, Welte T, Maus UA. Efficacy profiles of daptomycin for treatment of invasive and noninvasive pulmonary infections with Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy. 54: 707-17. PMID 19917756 DOI: 10.1128/Aac.00943-09  0.51
2009 Schachern PA, Tsuprun V, Cureoglu S, Ferrieri P, Briles DE, Paparella MM, Juhn S. Virulence of pneumococcal proteins on the inner ear. Archives of Otolaryngology--Head & Neck Surgery. 135: 657-61. PMID 19620586 DOI: 10.1001/Archoto.2009.72  0.44
2009 Winter C, Herbold W, Maus R, Länger F, Briles DE, Paton JC, Welte T, Maus UA. Important role for CC chemokine ligand 2-dependent lung mononuclear phagocyte recruitment to inhibit sepsis in mice infected with Streptococcus pneumoniae. Journal of Immunology (Baltimore, Md. : 1950). 182: 4931-7. PMID 19342672 DOI: 10.4049/Jimmunol.0804096  0.495
2009 Arévalo MT, Xu Q, Paton JC, Hollingshead SK, Pichichero ME, Briles DE, Girgis N, Zeng M. Mucosal vaccination with a multicomponent adenovirus-vectored vaccine protects against Streptococcus pneumoniae infection in the lung. Fems Immunology and Medical Microbiology. 55: 346-51. PMID 19291171 DOI: 10.1111/J.1574-695X.2008.00518.X  0.535
2009 Shah P, Briles DE, King J, Hale Y, Swiatlo E. Mucosal immunization with polyamine transport protein D (PotD) protects mice against nasopharyngeal colonization with Streptococcus pneumoniae. Experimental Biology and Medicine (Maywood, N.J.). 234: 403-9. PMID 19176871 DOI: 10.3181/0809-Rm-269  0.562
2009 Li J, Szalai AJ, Hollingshead SK, Nahm MH, Briles DE. Antibody to the type 3 capsule facilitates immune adherence of pneumococci to erythrocytes and augments their transfer to macrophages. Infection and Immunity. 77: 464-71. PMID 19001076 DOI: 10.1128/Iai.00892-08  0.472
2009 Schacher P, Ferrieri P, Tsuprun V, Briles D, Juhn S. SP328 – Effect of apolactoferrin on the middle-ear infection Otolaryngology - Head and Neck Surgery. 141: P185-P185. DOI: 10.1016/J.Otohns.2009.06.592  0.383
2008 Tsuprun V, Cureoglu S, Schachern PA, Ferrieri P, Briles DE, Paparella MM, Juhn SK. Role of pneumococcal proteins in sensorineural hearing loss due to otitis media. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 29: 1056-60. PMID 18833010 DOI: 10.1097/Mao.0B013E31818Af3Ad  0.418
2008 Torii I, Oka S, Hotomi M, Benjamin WH, Takai T, Kearney JF, Briles DE, Kubagawa H. PIR-B-deficient mice are susceptible to Salmonella infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 4229-39. PMID 18768880 DOI: 10.1182/Blood.V110.11.2420.2420  0.451
2008 Melin MM, Hollingshead SK, Briles DE, Lahdenkari MI, Kilpi TM, Käyhty HM. Development of antibodies to PspA families 1 and 2 in children after exposure to Streptococcus pneumoniae. Clinical and Vaccine Immunology : Cvi. 15: 1529-35. PMID 18753341 DOI: 10.1128/Cvi.00181-08  0.444
2008 Melin MM, Hollingshead SK, Briles DE, Hanage WP, Lahdenkari M, Kaijalainen T, Kilpi TM, Käyhty HM. Distribution of pneumococcal surface protein A families 1 and 2 among Streptococcus pneumoniae isolates from children in finland who had acute otitis media or were nasopharyngeal carriers. Clinical and Vaccine Immunology : Cvi. 15: 1555-63. PMID 18753340 DOI: 10.1128/Cvi.00177-08  0.427
2008 Wright AKA, Briles DE, Metzger DW, Gordon SB. Prospects for use of interleukin-12 as a mucosal adjuvant for vaccination of humans to protect against respiratory pneumococcal infection Vaccine. 26: 4893-4903. PMID 18602438 DOI: 10.1016/J.Vaccine.2008.06.058  0.462
2008 Schachern P, Tsuprun V, Cureoglu S, Ferrieri P, Briles D, Paparella M, Juhn S. The round window membrane in otitis media: effect of pneumococcal proteins. Archives of Otolaryngology--Head & Neck Surgery. 134: 658-62. PMID 18559736 DOI: 10.1001/Archotol.134.6.658  0.454
2008 Denzel A, Maus UA, Rodriguez Gomez M, Moll C, Niedermeier M, Winter C, Maus R, Hollingshead S, Briles DE, Kunz-Schughart LA, Talke Y, Mack M. Basophils enhance immunological memory responses. Nature Immunology. 9: 733-42. PMID 18516038 DOI: 10.1038/Ni.1621  0.429
2008 Glover DT, Hollingshead SK, Briles DE. Streptococcus pneumoniae surface protein PcpA elicits protection against lung infection and fatal sepsis. Infection and Immunity. 76: 2767-76. PMID 18391008 DOI: 10.1128/Iai.01126-07  0.547
2008 Ochs MM, Bartlett W, Briles DE, Hicks B, Jurkuvenas A, Lau P, Ren B, Millar A. Vaccine-induced human antibodies to PspA augment complement C3 deposition on Streptococcus pneumoniae. Microbial Pathogenesis. 44: 204-14. PMID 18006268 DOI: 10.1016/J.Micpath.2007.09.007  0.534
2008 Hembre BS, Briles DE, Grewal HM, Strand TA. Effect of high dose oral zinc in mice with severe infection with Streptococcus pneumoniae. Scandinavian Journal of Infectious Diseases. 40: 363-7. PMID 17963160 DOI: 10.1080/00365540701716833  0.46
2008 Taut K, Winter C, Briles DE, Paton JC, Christman JW, Maus R, Baumann R, Welte T, Maus UA. Macrophage Turnover Kinetics in the Lungs of Mice Infected with Streptococcus pneumoniae. American Journal of Respiratory Cell and Molecular Biology. 38: 105-13. PMID 17690327 DOI: 10.1165/Rcmb.2007-0132Oc  0.438
2007 Simell B, Melin M, Lahdenkari M, Briles DE, Hollingshead SK, Kilpi TM, Kayhty H. Antibodies to pneumococcal surface protein A families 1 and 2 in serum and saliva of children and the risk of pneumococcal acute otitis media. The Journal of Infectious Diseases. 196: 1528-36. PMID 18008233 DOI: 10.1086/522607  0.443
2007 Li J, Glover DT, Szalai AJ, Hollingshead SK, Briles DE. PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation. Infection and Immunity. 75: 5877-85. PMID 17923519 DOI: 10.1128/Iai.00839-07  0.495
2007 Darrieux M, Miyaji EN, Ferreira DM, Lopes LM, Lopes APY, Ren B, Briles DE, Hollingshead SK, Leite LCC. Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition Infection and Immunity. 75: 5930-5938. PMID 17923518 DOI: 10.1128/Iai.00940-07  0.495
2007 Lim JH, Stirling B, Derry J, Koga T, Jono H, Woo CH, Xu H, Bourne P, Ha UH, Ishinaga H, Xu H, Andalibi A, Feng XH, Zhu H, Huang Y, ... ... Briles DE, et al. Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections. Immunity. 27: 349-60. PMID 17723219 DOI: 10.1016/J.Immuni.2007.07.011  0.417
2007 Winter C, Taut K, Länger F, Mack M, Briles DE, Paton JC, Maus R, Srivastava M, Welte T, Maus UA. FMS-like tyrosine kinase 3 ligand aggravates the lung inflammatory response to Streptococcus pneumoniae infection in mice: role of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 3099-108. PMID 17709524 DOI: 10.4049/Jimmunol.179.5.3099  0.464
2007 Basset A, Thompson CM, Hollingshead SK, Briles DE, Ades EW, Lipsitch M, Malley R. Antibody-independent, CD4+ T-cell-dependent protection against pneumococcal colonization elicited by intranasal immunization with purified pneumococcal proteins. Infection and Immunity. 75: 5460-4. PMID 17698570 DOI: 10.1128/Iai.00773-07  0.506
2007 Senkovich O, Cook WJ, Mirza S, Hollingshead SK, Protasevich II, Briles DE, Chattopadhyay D. Structure of a complex of human lactoferrin N-lobe with pneumococcal surface protein a provides insight into microbial defense mechanism. Journal of Molecular Biology. 370: 701-13. PMID 17543335 DOI: 10.1016/J.Jmb.2007.04.075  0.641
2007 Winter C, Taut K, Srivastava M, Länger F, Mack M, Briles DE, Paton JC, Maus R, Welte T, Gunn MD, Maus UA. Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis. Journal of Immunology (Baltimore, Md. : 1950). 178: 5828-38. PMID 17442967 DOI: 10.1055/S-2007-1032293  0.5
2007 Maus UA, Backi M, Winter C, Srivastava M, Schwarz MK, Rückle T, Paton JC, Briles D, Mack M, Welte T, Maus R, Bohle RM, Seeger W, Rommel C, Hirsch E, et al. Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection. American Journal of Respiratory and Critical Care Medicine. 175: 958-66. PMID 17322108 DOI: 10.1164/Rccm.200610-1533Oc  0.388
2007 Ogunniyi AD, LeMessurier KS, Graham RM, Watt JM, Briles DE, Stroeher UH, Paton JC. Contributions of pneumolysin, pneumococcal surface protein A (PspA), and PspC to pathogenicity of Streptococcus pneumoniae D39 in a mouse model. Infection and Immunity. 75: 1843-51. PMID 17261599 DOI: 10.1128/Iai.01384-06  0.516
2007 Ogunniyi AD, Grabowicz M, Briles DE, Cook J, Paton JC. Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae. Infection and Immunity. 75: 350-7. PMID 17088353 DOI: 10.1128/Iai.01103-06  0.564
2006 Simell B, Jaakkola T, Lahdenkari M, Briles D, Hollingshead S, Kilpi TM, Käyhty H. Serum antibodies to pneumococcal neuraminidase NanA in relation to pneumococcal carriage and acute otitis media. Clinical and Vaccine Immunology : Cvi. 13: 1177-9. PMID 16928889 DOI: 10.1128/Cvi.00257-06  0.472
2006 Baril L, Dietemann J, Essevaz-Roulet M, Béniguel L, Coan P, Briles DE, Guy B, Cozon G. Pneumococcal surface protein A (PspA) is effective at eliciting T cell-mediated responses during invasive pneumococcal disease in adults. Clinical and Experimental Immunology. 145: 277-86. PMID 16879247 DOI: 10.1111/J.1365-2249.2006.03148.X  0.506
2006 Bernstein JM, Haase E, Hasse E, Scannapieco F, Dryja D, Wolf J, Briles D, King J, Wilding GE. Bacterial interference of penicillin-sensitive and -resistant Streptococcus pneumoniae by Streptococcus oralis in an adenoid organ culture: implications for the treatment of recurrent upper respiratory tract infections in children and adults. The Annals of Otology, Rhinology, and Laryngology. 115: 350-6. PMID 16739666 DOI: 10.1177/000348940611500506  0.402
2006 Daniels CC, Briles TC, Mirza S, Håkansson AP, Briles DE. Capsule does not block antibody binding to PspA, a surface virulence protein of Streptococcus pneumoniae. Microbial Pathogenesis. 40: 228-33. PMID 16540281 DOI: 10.1016/J.Micpath.2006.01.007  0.792
2006 Palaniappan R, Singh S, Singh UP, Singh R, Ades EW, Briles DE, Hollingshead SK, Royal W, Sampson JS, Stiles JK, Taub DD, Lillard JW. CCL5 modulates pneumococcal immunity and carriage. Journal of Immunology (Baltimore, Md. : 1950). 176: 2346-56. PMID 16455992 DOI: 10.4049/Jimmunol.176.4.2346  0.466
2006 Hollingshead SK, Baril L, Ferro S, King J, Coan P, Briles DE. Pneumococcal surface protein A (PspA) family distribution among clinical isolates from adults over 50 years of age collected in seven countries. Journal of Medical Microbiology. 55: 215-21. PMID 16434715 DOI: 10.1099/Jmm.0.46268-0  0.455
2006 Johnston JW, Briles DE, Myers LE, Hollingshead SK. Mn2+-dependent regulation of multiple genes in Streptococcus pneumoniae through PsaR and the resultant impact on virulence. Infection and Immunity. 74: 1171-80. PMID 16428766 DOI: 10.1128/Iai.74.2.1171-1180.2006  0.618
2005 Briles DE, Novak L, Hotomi M, van Ginkel FW, King J. Nasal colonization with Streptococcus pneumoniae includes subpopulations of surface and invasive pneumococci. Infection and Immunity. 73: 6945-51. PMID 16177374 DOI: 10.1128/Iai.73.10.6945-6951.2005  0.413
2005 Coats MT, Benjamin WH, Hollingshead SK, Briles DE. Antibodies to the pneumococcal surface protein A, PspA, can be produced in splenectomized and can protect splenectomized mice from infection with Streptococcus pneumoniae. Vaccine. 23: 4257-62. PMID 16005736 DOI: 10.1016/J.Vaccine.2005.03.039  0.825
2005 Johnson CN, Briles DE, Benjamin WH, Hollingshead SK, Waites KB. Relative fitness of fluoroquinolone-resistant Streptococcus pneumoniae. Emerging Infectious Diseases. 11: 814-20. PMID 15963274 DOI: 10.3201/Eid1106.040840  0.446
2005 Gor DO, Ding X, Briles DE, Jacobs MR, Greenspan NS. Relationship between surface accessibility for PpmA, PsaA, and PspA and antibody-mediated immunity to systemic infection by Streptococcus pneumoniae. Infection and Immunity. 73: 1304-12. PMID 15731027 DOI: 10.1128/Iai.73.3.1304-1312.2005  0.603
2005 Payne DB, Sun A, Butler JC, Singh SP, Hollingshead SK, Briles DE. PspA family typing and PCR-based DNA fingerprinting with BOX A1R primer of pneumococci from the blood of patients in the USA with and without sickle cell disease. Epidemiology and Infection. 133: 173-8. PMID 15724724 DOI: 10.1017/S0950268804003085  0.714
2005 Palaniappan R, Singh S, Singh UP, Sakthivel SK, Ades EW, Briles DE, Hollingshead SK, Paton JC, Sampson JS, Lillard JW. Differential PsaA-, PspA-, PspC-, and PdB-specific immune responses in a mouse model of pneumococcal carriage. Infection and Immunity. 73: 1006-13. PMID 15664944 DOI: 10.1128/Iai.73.2.1006-1013.2005  0.498
2005 Janoff EN, Briles DE, Rubins JB. Respiratory bacterial vaccines Mucosal Immunology, Two-Volume Set. 905-921. DOI: 10.1016/B978-012491543-5/50054-1  0.436
2004 Ren B, McCrory MA, Pass C, Bullard DC, Ballantyne CM, Xu Y, Briles DE, Szalai AJ. The virulence function of Streptococcus pneumoniae surface protein A involves inhibition of complement activation and impairment of complement receptor-mediated protection. Journal of Immunology (Baltimore, Md. : 1950). 173: 7506-12. PMID 15585877 DOI: 10.4049/Jimmunol.173.12.7506  0.437
2004 Baril L, Briles DE, Crozier P, King J, Punar M, Hollingshead SK, McCormick JB. Characterization of antibodies to PspA and PsaA in adults over 50 years of age with invasive pneumococcal disease. Vaccine. 23: 789-93. PMID 15542203 DOI: 10.1016/J.Vaccine.2004.07.033  0.43
2004 Johnston JW, Myers LE, Ochs MM, Benjamin WH, Briles DE, Hollingshead SK. Lipoprotein PsaA in virulence of Streptococcus pneumoniae: surface accessibility and role in protection from superoxide. Infection and Immunity. 72: 5858-67. PMID 15385487 DOI: 10.1128/Iai.72.10.5858-5867.2004  0.588
2004 Shaper M, Hollingshead SK, Benjamin WH, Briles DE. PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin [corrected]. Infection and Immunity. 72: 5031-40. PMID 15321996 DOI: 10.1128/Iai.72.9.5031-5040.2004  0.532
2004 Mollerach M, Regueira M, Bonofiglio L, Callejo R, Pace J, Di Fabio JL, Hollingshead S, Briles D, Tregnaghi M, Balbi de Aguirre L, Aprá E, Vazquez M, Galanternic L, Procopio A, Logarzo D, et al. Invasive Streptococcus pneumoniae isolates from Argentinian children: Serotypes, families of pneumococcal surface protein A (PspA) and genetic diversity Epidemiology and Infection. 132: 177-184. PMID 15061491 DOI: 10.1017/S0950268803001626  0.474
2004 Briles DE. Protection of the elderly from pneumococcal pneumonia with a protein-based vaccine? Mechanisms of Ageing and Development. 125: 129-31. PMID 15037017 DOI: 10.1016/J.Mad.2003.11.008  0.542
2004 Baril L, Briles DE, Crozier P, King JD, Hollingshead SK, Murphy TF, Mccormick JB. Natural materno-fetal transfer of antibodies to PspA and to PsaA Clinical and Experimental Immunology. 135: 474-477. PMID 15008981 DOI: 10.1111/J.1365-2249.2003.02357.X  0.456
2004 Ren B, Szalai AJ, Hollingshead SK, Briles DE. Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface. Infection and Immunity. 72: 114-22. PMID 14688088 DOI: 10.1128/Iai.72.1.114-122.2004  0.495
2003 Swiatlo E, King J, Nabors GS, Mathews B, Briles DE. Pneumococcal Surface Protein A Is Expressed in Vivo, and Antibodies to PspA Are Effective for Therapy in a Murine Model of Pneumococcal Sepsis Infection and Immunity. 71: 7149-7153. PMID 14638806 DOI: 10.1128/Iai.71.12.7149-7153.2003  0.583
2003 van Ginkel FW, McGhee JR, Watt JM, Campos-Torres A, Parish LA, Briles DE. Pneumococcal carriage results in ganglioside-mediated olfactory tissue infection. Proceedings of the National Academy of Sciences of the United States of America. 100: 14363-7. PMID 14610280 DOI: 10.1073/Pnas.2235844100  0.356
2003 Lynch JM, Briles DE, Metzger DW. Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12. Infection and Immunity. 71: 4780-8. PMID 12874361 DOI: 10.1128/Iai.71.8.4780-4788.2003  0.528
2003 Roche H, Ren B, McDaniel LS, Håkansson A, Briles DE. Relative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae. Infection and Immunity. 71: 4498-505. PMID 12874329 DOI: 10.1128/Iai.71.8.4498-4505.2003  0.717
2003 Briles DE, Hollingshead SK, Paton JC, Ades EW, Novak L, van Ginkel FW, Benjamin WH. Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae. The Journal of Infectious Diseases. 188: 339-48. PMID 12870114 DOI: 10.1086/376571  0.588
2003 Yu J, Briles DE, Englund JA, Hollingshead SK, Glezen WP, Nahm MH. Immunogenic protein contaminants in pneumococcal vaccines. The Journal of Infectious Diseases. 187: 1019-23. PMID 12660950 DOI: 10.1086/368200  0.482
2003 Strand TA, Hollingshead SK, Julshamn K, Briles DE, Blomberg B, Sommerfelt H. Effects of zinc deficiency and pneumococcal surface protein a immunization on zinc status and the risk of severe infection in mice. Infection and Immunity. 71: 2009-13. PMID 12654820 DOI: 10.1128/Iai.71.4.2009-2013.2003  0.521
2003 Roche H, Håkansson A, Hollingshead SK, Briles DE. Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection model. Infection and Immunity. 71: 1033-41. PMID 12595413 DOI: 10.1128/Iai.71.3.1033-1041.2003  0.672
2003 Ren B, Szalai AJ, Thomas O, Hollingshead SK, Briles DE. Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae. Infection and Immunity. 71: 75-85. PMID 12496151 DOI: 10.1128/Iai.71.1.75-85.2003  0.463
2003 Briles DE, Hollingshead SK, Crain MJ, Ren B, Mirza S, Watt J, Johnston J. Pneumococcal proteins that may constitute the next generation vaccine for pneumococcal disease International Congress Series. 1257: 27-31. DOI: 10.1016/S0531-5131(03)01157-9  0.698
2002 Haas KM, Hasegawa M, Steeber DA, Poe JC, Zabel MD, Bock CB, Karp DR, Briles DE, Weis JH, Tedder TF. Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses. Immunity. 17: 713-23. PMID 12479818 DOI: 10.1016/S1074-7613(02)00483-1  0.456
2002 Robinson DA, Briles DE, Crain MJ, Hollingshead SK. Evolution and virulence of serogroup 6 pneumococci on a global scale. Journal of Bacteriology. 184: 6367-75. PMID 12399507 DOI: 10.1128/Jb.184.22.6367-6375.2002  0.42
2002 Smith AW, Roche H, Trombe MC, Briles DE, HÃ¥kansson A. Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection. Molecular Microbiology. 44: 431-48. PMID 11972781 DOI: 10.1046/J.1365-2958.2002.02883.X  0.676
2002 Balachandran P, Brooks-Walter A, Virolainen-Julkunen A, Hollingshead SK, Briles DE. Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae. Infection and Immunity. 70: 2526-34. PMID 11953392 DOI: 10.1128/Iai.70.5.2526-2534.2002  0.739
2001 Vela Coral MC, Fonseca N, Castañeda E, Di Fabio JL, Hollingshead SK, Briles DE. Pneumococcal surface protein A of invasive Streptococcus pneumoniae isolates from Colombian children Emerging Infectious Diseases. 7: 832-836. PMID 11747695 DOI: 10.3201/Eid0705.017510  0.511
2001 Arulanandam BP, Lynch JM, Briles DE, Hollingshead S, Metzger DW. Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection. Infection and Immunity. 69: 6718-24. PMID 11598043 DOI: 10.1128/Iai.69.11.6718-6724.2001  0.499
2001 Strand TA, Briles DE, Gjessing HK, Maage A, Bhan MK, Sommerfelt H. Pneumococcal pulmonary infection, septicaemia and survival in young zinc-depleted mice British Journal of Nutrition. 86: 301-306. PMID 11502245 DOI: 10.1079/Bjn2001399  0.449
2001 Malley R, Lipsitch M, Stack A, Saladino R, Fleisher G, Pelton S, Thompson C, Briles D, Anderson P. Intranasal immunization with killed unencapsulated whole cells prevents colonization and invasive disease by capsulated pneumococci. Infection and Immunity. 69: 4870-3. PMID 11447162 DOI: 10.1128/Iai.69.8.4870-4873.2001  0.535
2001 Depiero A, Kaminski DA, Halsey JF, Briles D, Burrows PD, Hostoffer RW. Immunologic compensation in a patient with a large IgH constant region deletion. The Journal of Allergy and Clinical Immunology. 107: 1051-5. PMID 11398084 DOI: 10.1067/Mai.2001.115094  0.501
2001 Balachandran P, Hollingshead SK, Paton JC, Briles DE. The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin. Journal of Bacteriology. 183: 3108-16. PMID 11325939 DOI: 10.1128/Jb.183.10.3108-3116.2001  0.69
2001 Robinson DA, Edwards KM, Waites KB, Briles DE, Crain MJ, Hollingshead SK. Clones of Streptococcus pneumoniae isolated from nasopharyngeal carriage and invasive disease in young children in central Tennessee. The Journal of Infectious Diseases. 183: 1501-7. PMID 11319686 DOI: 10.1086/320194  0.394
2001 Håkansson A, Roche H, Mirza S, McDaniel LS, Brooks-Walter A, Briles DE. Characterization of binding of human lactoferrin to pneumococcal surface protein A. Infection and Immunity. 69: 3372-81. PMID 11292760 DOI: 10.1128/Iai.69.5.3372-3381.2001  0.733
2001 Buchanan RM, Briles DE, Arulanandam BP, Westerink MAJ, Raeder RH, Metzger DW. IL-12-mediated increases in protection elicited by pneumococcal and meningococcal conjugate vaccines Vaccine. 19: 2020-2028. PMID 11228373 DOI: 10.1016/S0264-410X(00)00421-7  0.472
2001 Hollingshead SK, Briles DE. Streptococcus pneumoniae: New tools for an old pathogen Current Opinion in Microbiology. 4: 71-77. PMID 11173037 DOI: 10.1016/S1369-5274(00)00167-3  0.447
2000 Briles DE, Hollingshead SK, Nabors GS, Paton JC, Brooks-Walter A. The potential for using protein vaccines to protect against otitis media caused by Streptococcus pneumoniae Vaccine. 19. PMID 11163470 DOI: 10.1016/S0264-410X(00)00285-1  0.513
2000 Briles DE, Hollingshead SK, King J, Swift A, Braun PA, Park MK, Ferguson LM, Nahm MH, Nabors GS. Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA Journal of Infectious Diseases. 182: 1694-1701. PMID 11069242 DOI: 10.1086/317602  0.586
2000 Hollingshead SK, Becker R, Briles DE. Diversity of PspA: Mosaic genes and evidence for past recombination in Streptococcus pneumoniae Infection and Immunity. 68: 5889-5900. PMID 10992499 DOI: 10.1128/Iai.68.10.5889-5900.2000  0.448
2000 Rapola S, Jäntti V, Haikala R, Syrjänen R, Carlone GM, Sampson JS, Briles DE, Paton JC, Takala AK, Kilpi TM, Käyhty H. Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and acute otitis media. The Journal of Infectious Diseases. 182: 1146-52. PMID 10979911 DOI: 10.1086/315822  0.528
2000 Lipsitch M, Dykes JK, Johnson SE, Ades EW, King J, Briles DE, Carlone GM. Competition among Streptococcus pneumoniae for intranasal colonization in a mouse model Vaccine. 18: 2895-2901. PMID 10812233 DOI: 10.1016/S0264-410X(00)00046-3  0.52
2000 Park MK, Briles DE, Nahm MH. A latex bead-based flow cytometric immunoassay capable of simultaneous typing of multiple pneumococcal serotypes (multibead assay) Clinical and Diagnostic Laboratory Immunology. 7: 486-489. PMID 10799465 DOI: 10.1128/Cdli.7.3.486-489.2000  0.401
2000 Nahm MH, Briles DE, Yu X. Development of a multi-specificity opsonophagocytic killing assay Vaccine. 18: 2768-2771. PMID 10781864 DOI: 10.1016/S0264-410X(00)00044-X  0.471
2000 Ogunniyi AD, Folland RL, Briles DE, Hollingshead SK, Paton JC. Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae Infection and Immunity. 68: 3028-3033. PMID 10769009 DOI: 10.1128/IAI.68.5.3028-3033.2000  0.471
2000 De BK, Sampson JS, Ades EW, Huebner RC, Jue DL, Johnson SE, Espina M, Stinson AR, Briles DE, Carlone GM. Purification and characterization of Streptococcus pneumoniae palmitoylated pneumococcal surface adhesin A expressed in Escherichia coli. Vaccine. 18: 1811-21. PMID 10699329 DOI: 10.1016/S0264-410X(99)00481-8  0.501
2000 Nabors GS, Braun PA, Herrmann DJ, Heise ML, Pyle DJ, Gravenstein S, Schilling M, Ferguson LM, Hollingshead SK, Briles DE, Becker RS. Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules Vaccine. 18: 1743-1754. PMID 10699322 DOI: 10.1016/S0264-410X(99)00530-7  0.544
2000 Virolainen A, Russell W, Crain MJ, Rapola S, Käyhty H, Briles DE. Human antibodies to pneumococcal surface protein A in health and disease Pediatric Infectious Disease Journal. 19: 134-138. PMID 10694000 DOI: 10.1097/00006454-200002000-00011  0.484
2000 Briles DE, Hollingshead S, Brooks-Walter A, Nabors GS, Ferguson L, Schilling M, Gravenstein S, Braun P, King J, Swift A. The potential to use PspA and other pneumococcal proteins to elicit protection against pneumococcal infection Vaccine. 18: 1707-1711. PMID 10689153 DOI: 10.1016/S0264-410X(99)00511-3  0.555
2000 Briles DE, Ades E, Paton JC, Sampson JS, Carlone GM, Huebner RC, Virolainen A, Swiatlo E, Hollingshead SK. Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae. Infection and Immunity. 68: 796-800. PMID 10639448 DOI: 10.1128/Iai.68.2.796-800.2000  0.535
2000 Hwang YI, Nahm MH, Briles DE, Thomas D, Purkerson JM. Acquired, but not innate, immune responses to Streptococcus pneumoniae are compromised by neutralization of CD40L Infection and Immunity. 68: 511-517. PMID 10639411 DOI: 10.1128/Iai.68.2.511-517.2000  0.55
2000 Jedrzejas MJ, Hollingshead SK, Lebowitz J, Chantalat L, Briles DE, Lamani E. Production and characterization of the functional fragment of pneumococcal surface protein A. Archives of Biochemistry and Biophysics. 373: 116-25. PMID 10620330 DOI: 10.1006/Abbi.1999.1544  0.476
1999 Brooks-Walter A, Briles DE, Hollingshead SK. The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia Infection and Immunity. 67: 6533-6542. PMID 10569772 DOI: 10.1128/Iai.67.12.6533-6542.1999  0.5
1999 Tu AHT, Fulgham RL, Mccrory MA, Briles DE, Szalai AJ. Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae Infection and Immunity. 67: 4720-4724. PMID 10456922 DOI: 10.1128/Iai.67.9.4720-4724.1999  0.543
1999 White P, Hermansson A, Svanborg C, Briles D, Prellner K. Effects of active immunization with a pneumococcal surface protein (PspA) and of locally applied antibodies in experimental otitis media. Operations Research Letters. 61: 206-211. PMID 10450055 DOI: 10.1159/000027672  0.5
1999 Circolo A, Garnier G, Fukuda W, Wang X, Hidvegi T, Szalai AJ, Briles DE, Volanakis JE, Wetsel RA, Colten HR. Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA. Immunopharmacology. 42: 135-49. PMID 10408374 DOI: 10.1016/S0162-3109(99)00021-1  0.428
1999 Prellner K, Hermansson A, White P, Melhus Å, Briles D. Immunization and protection in pneumococcal otitis media studied in a rat model. Microbial Drug Resistance. 5: 73-82. PMID 10332724 DOI: 10.1089/Mdr.1999.5.73  0.482
1999 O'Brien DP, Briles DE, Szalai AJ, Tu AH, Sanz I, Nahm MH. Tumor necrosis factor alpha receptor I is important for survival from Streptococcus pneumoniae infections Infection and Immunity. 67: 595-601. PMID 9916064 DOI: 10.1128/Iai.67.2.595-601.1999  0.465
1999 Robinson DA, Turner JS, Facklam RR, Parkinson AJ, Breiman RF, Gratten M, Steinhoff MC, Hollingshead SK, Briles DE, Crain MJ. Molecular characterization of a globally distributed lineage of serotype 12F Streptococcus pneumoniae causing invasive disease. The Journal of Infectious Diseases. 179: 414-22. PMID 9878026 DOI: 10.1086/314589  0.441
1998 Yamamoto M, Briles DE, Yamamoto S, Ohmura M, Kiyono H, McGhee JR. A nontoxic adjuvant for mucosal immunity to pneumococcal surface protein A. Journal of Immunology (Baltimore, Md. : 1950). 161: 4115-21. PMID 9780183  0.456
1998 Robinson DA, Hollingshead SK, Musser JM, Parkinson AJ, Briles DE, Crain MJ. The IS1167 insertion sequence is a phylogenetically informative marker among isolates of serotype 6B Streptococcus pneumoniae. Journal of Molecular Evolution. 47: 222-9. PMID 9694671 DOI: 10.1007/Pl00006379  0.413
1998 Nayak AR, Tinge SA, Tart RC, McDaniel LS, Briles DE, Curtiss R. A live recombinant avirulent oral Salmonella vaccine expressing pneumococcal surface protein a induces protective responses against Streptococcus pneumoniae Infection and Immunity. 66: 3744-3751. PMID 9673257 DOI: 10.1128/Iai.66.8.3744-3751.1998  0.576
1998 Wortham C, Grinberg L, Kaslow DC, Briles DE, Mcdaniel LS, Lees A, Flora M, Snapper CM, Mond JJ. Enhanced Protective Antibody Responses to PspA after Intranasal or Subcutaneous Injections of PspA Genetically Fused to Granulocyte-Macrophage Colony-Stimulating Factor or Interleukin-2 Infection and Immunity. 66: 1513-1520. PMID 9529075 DOI: 10.1128/Iai.66.4.1513-1520.1998  0.491
1998 Benton KA, VanCott JL, Briles DE. Role of tumor necrosis factor alpha in the host response of mice to bacteremia caused by pneumolysin-deficient Streptococcus pneumoniae. Infection and Immunity. 66: 839-42. PMID 9453652 DOI: 10.1128/Iai.66.2.839-842.1998  0.457
1998 Wortham C, Grinberg L, Kaslow DC, Briles DE, McDaniel LS, Lees A, Flora M, Snapper CM, Mond JJ. Enhanced Protective Antibody Responses to PspA after Intranasal or Subcutaneous Injections of PspA Genetically Fused to Granulocyte-Macrophage Colony-Stimulating Factor or Interleukin-2 Infection and Immunity. 66: 1513-1520. DOI: 10.1128/iai.66.4.1513-1520.1998  0.442
1998 McDaniel LS, McDaniel DO, Hollingshead SK, Briles DE. Comparison of the PspA Sequence from Streptococcus pneumoniae EF5668 to the Previously Identified PspA Sequence from Strain Rx1 and Ability of PspA from EF5668 To Elicit Protection against Pneumococci of Different Capsular Types Infection and Immunity. 66: 4748-4754. DOI: 10.1128/iai.66.10.4748-4754.1998  0.438
1998 Briles DE, Tart RC, Swiatlo E, Dillard JP, Smith P, Benton KA, Ralph BA, Brooks-Walter A, Crain MJ, Hollingshead SK, McDaniel LS. Pneumococcal Diversity: Considerations for New Vaccine Strategies with Emphasis on Pneumococcal Surface Protein A (PspA) Clinical Microbiology Reviews. 11: 645-657. DOI: 10.1128/Cmr.11.4.645  0.541
1997 Briles DE, Hollingshead SK, Swiatlo E, Brooks-Walter A, Szalai A, Virolainen A, McDaniel LS, Benton KA, White P, Prellner K, Hermansson A, Aerts PC, Van Dijk H, Crain MJ. PspA and PspC: their potential for use as pneumococcal vaccines. Microbial Drug Resistance (Larchmont, N.Y.). 3: 401-8. PMID 9442494 DOI: 10.1089/Mdr.1997.3.401  0.43
1997 Saladino RA, Stack AM, Fleisher GR, Thompson CM, Briles DE, Kobzik L, Siber GR. Development of a model of low-inoculum Streptococcus pneumoniae intrapulmonary infection in infant rats Infection and Immunity. 65: 4701-4704. PMID 9353053 DOI: 10.1128/Iai.65.11.4701-4704.1997  0.411
1997 Benton KA, Paton JC, Briles DE. The hemolytic and complement-activating properties of pneumolysin do not contribute individually to virulence in a pneumococcal bacteremia model. Microbial Pathogenesis. 23: 201-9. PMID 9344781 DOI: 10.1006/Mpat.1997.0150  0.444
1997 Wu HY, Virolainen A, Mathews B, King J, Russell MW, Briles DE. Establishment of a Streptococcus pneumoniae nasopharyngeal colonization model in adult mice Microbial Pathogenesis. 23: 127-137. PMID 9281471 DOI: 10.1006/Mpat.1997.0142  0.532
1997 McDaniel LS, Loechel F, Benedict C, Greenway T, Briles DE, Corny RM, Curiel DT. Immunization with a plasmid expressing pneumococcal surface protein A (PspA) can elicit protection against fatal infection with Streptococcus pneumoniae Gene Therapy. 4: 375-377. PMID 9176525 DOI: 10.1038/Sj.Gt.3300401  0.527
1997 Swiatlo E, Brooks-Walter A, Briles DE, McDaniel LS. Oligonucleotides identify conserved and variable regions of pspA and pspA-like sequences of Streptococcus pneumoniae Gene. 188: 279-284. PMID 9133603 DOI: 10.1016/S0378-1119(96)00823-2  0.435
1997 Benton KA, Paton JC, Briles DE. Differences in virulence for mice among Streptococcus pneumoniae strains of capsular types 2, 3, 4, 5, and 6 are not attributable to differences in pneumolysin production. Infection and Immunity. 65: 1237-44. PMID 9119457 DOI: 10.1128/Iai.65.4.1237-1244.1997  0.46
1997 Wu HY, Nahm MH, Guo Y, Russell MW, Briles DE. Intranasal immunization of mice with PspA (Pneumococcal surface protein A) can prevent lntranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae Journal of Infectious Diseases. 175: 839-846. PMID 9086139 DOI: 10.1086/513980  0.541
1997 Yamamoto M, McDaniel LS, Kawabata K, Briles DE, Jackson RJ, McGhee JR, Kiyono H. Oral immunization with PspA elicits protective humoral immunity against Streptococcus pneumoniae infection. Infection and Immunity. 65: 640-4. PMID 9009325 DOI: 10.1128/Iai.65.2.640-644.1997  0.55
1996 Briles DE, Tart RC, Wu HY, Ralph BA, Russell MW, McDaniel LS. Systemic and mucosal protective immunity to pneumococcal surface protein A Annals of the New York Academy of Sciences. 797: 118-126. PMID 8993356 DOI: 10.1111/J.1749-6632.1996.Tb52954.X  0.53
1996 Cartner SC, Simecka JW, Briles DE, Cassell GH, Lindsey JR. Resistance to mycoplasmal lung disease in mice is a complex genetic trait Infection and Immunity. 64: 5326-5331. PMID 8945584 DOI: 10.1128/Iai.64.12.5326-5331.1996  0.465
1996 Crain MJ, Turner JS, Robinson DA, Coffey TJ, Brooks-Walter A, McDaniel LS, Briles DE. Evidence for the simultaneous expression of two PspAs by a clone of capsular serotype 6B Streptococcus pneumoniae. Microbial Pathogenesis. 21: 265-75. PMID 8905615 DOI: 10.1006/mpat.1996.0060  0.423
1996 Szalai AJ, Briles DE, Volanakis JE. Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae Infection and Immunity. 64: 4850-4853. PMID 8890251 DOI: 10.1128/Iai.64.11.4850-4853.1996  0.497
1996 Briles DE, King JD, Gray MA, McDaniel LS, Swiatlo E, Benton KA. PspA, a protection-eliciting pneumococcal protein: immunogenicity of isolated native PspA in mice. Vaccine. 14: 858-67. PMID 8843627 DOI: 10.1016/0264-410X(96)82948-3  0.536
1996 Swiatlo E, Crain MJ, McDaniel LS, Brooks-Walter A, Coffey TJ, Spratt BG, Morrison DA, Briles DE. DNA polymorphisms and variant penicillin-binding proteins as evidence that relatively penicillin-resistant pneumococci in western Canada are clonally related. The Journal of Infectious Diseases. 174: 884-8. PMID 8843237 DOI: 10.1093/Infdis/174.4.884  0.429
1996 Swiatlo E, Benton K, Briles DE. Pneumococcal vaccine response in human immunodeficiency virus-infected patients. The Journal of Infectious Diseases. 173: 777-8. PMID 8627053 DOI: 10.1093/Infdis/173.3.777  0.446
1996 Tart RC, McDaniel LS, Ralph BA, Briles DE. Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice Journal of Infectious Diseases. 173: 380-386. PMID 8568299 DOI: 10.1093/Infdis/173.2.380  0.559
1996 Wu HY, Briles DE, Russell MW. Recombinant cholera toxin B subuntt (RCTB) as a mucosal adjuvant Faseb Journal. 10.  0.436
1996 Russell MW, Wu HY, Hajishengallis G, Harokopakis E, Briles DE, Michalek SM, Mestecky J. IgA antibodies and mucosal immune protection Periodicum Biologorum. 98: 413-419.  0.455
1995 Benton KA, Everson MP, Briles DE. A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice. Infection and Immunity. 63: 448-55. PMID 7822009 DOI: 10.1128/Iai.63.2.448-455.1995  0.495
1995 Szalai AJ, Briles DE, Volanakis JE. Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice Journal of Immunology. 155: 2557-2563. PMID 7650385  0.423
1994 Dunlap NE, Benjamin WH, Briles DE. The intracellular nature of Salmonella infection during the early stages of mouse typhoid Immunology Series. 60: 303-312. PMID 8251577  0.345
1994 Langermann S, Palaszynski SR, Burlein JE, Koenig S, Hanson MS, Briles DE, Stover CK. Protective humoral response against pneumococcal infection in mice elicited by recombinant bacille Calmette-Guérin vaccines expressing pneumococcal surface protein A Journal of Experimental Medicine. 180: 2277-2286. PMID 7964500  0.536
1994 Ralph BA, Briles DE, McDaniel LS. Cross-reactive protection eliciting epitopes of pneumococcal surface protein A Annals of the New York Academy of Sciences. 730: 361-363. PMID 7521605 DOI: 10.1111/J.1749-6632.1994.Tb44293.X  0.458
1993 Dunlap NE, Ballinger S, Reed T, Christian JC, Koopman WJ, Briles DE. The Use of Monozygotic and Dizygotic Twins to Estimate the Effects of Inheritance on the Levels of Immunoglobulin Isotypes and Antibodies to Phosphocholine Clinical Immunology and Immunopathology. 66: 176-180. PMID 8453788 DOI: 10.1006/Clin.1993.1022  0.441
1993 Dunlap NE, Briles DE. Immunology of tuberculosis Medical Clinics of North America. 77: 1235-1251. PMID 8231409 DOI: 10.1016/S0025-7125(16)30190-0  0.403
1992 Yother J, Handsome GL, Briles DE. Truncated forms of PspA that are secreted from Streptococcus pneumoniae and their use in functional studies and cloning of the pspA gene Journal of Bacteriology. 174: 610-618. PMID 1729250 DOI: 10.1128/Jb.174.2.610-618.1992  0.722
1992 Yother J, Briles DE. Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis Journal of Bacteriology. 174: 601-609. PMID 1729249 DOI: 10.1128/Jb.174.2.601-609.1992  0.701
1992 Briles DE, Crain MJ, Gray BM, Forman C, Yother J. Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae. Infection and Immunity. 60: 111-6. PMID 1729176 DOI: 10.1128/Iai.60.1.111-116.1992  0.741
1992 Munoz R, Musser JM, Crain M, Briles DE, Marton A, Parkinson AJ, Sorensen U, Tomasz A. Geographic distribution of penicillin-resistant clones of Streptococcus pneumoniae: characterization by penicillin-binding protein profile, surface protein A typing, and multilocus enzyme analysis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 15: 112-8. PMID 1617050 DOI: 10.1093/Clinids/15.1.112  0.452
1992 Briles DE, Forman C, Crain M. Mouse antibody to phosphocholine can protect mice from infection with mouse-virulent human isolates of Streptococcus pneumoniae Infection and Immunity. 60: 1957-1962. PMID 1563788 DOI: 10.1128/Iai.60.5.1957-1962.1992  0.546
1992 Kraft AS, Hall P, Pettit GR, Adler V, Benjamin WH, Briles DE. In Vivo Administration of Bryostatin 1, a Protein Kinase C Activator, Decreases Murine Resistance to Salmonella typhimurium Cancer Research. 52: 2143-2147. PMID 1559218  0.398
1992 Douglas Waltman W, Talkington DF, Lipinski AE, Crain MJ, Dixon JMS, Briles DE. Evidence for a Clonal Origin of Relative Penicillin Resistance among Type 9L Pneumococci in Northwestern Canada Journal of Infectious Diseases. 165: 671-675. PMID 1552195 DOI: 10.1093/Infdis/165.4.671  0.417
1992 McDaniel LS, Sheffield JS, Swiatlo E, Yother J, Crain MJ, Briles DE. Molecular localization of variable and conserved regions of pspA and identification of additional pspA homologous sequences in Streptococcus pneumoniae Microbial Pathogenesis. 13: 261-269. PMID 1363703 DOI: 10.1016/0882-4010(92)90036-N  0.706
1992 Talkington DF, Voellinger DC, Mcdaniel LS, Briles DE. Analysis of pneumococcal PspA microheterogeneity in SDS polyacrylamide gels and the association of PspA with the cell membrane Microbial Pathogenesis. 13: 343-355. PMID 1297913 DOI: 10.1016/0882-4010(92)90078-3  0.424
1992 Dunlap NE, Benjamin WH, Berry AK, Eldridge JH, Briles DE. A 'safe-site' for Salmonella typhimurium is within splenic polymorphonuclear cells Microbial Pathogenesis. 13: 181-190. PMID 1291841 DOI: 10.1016/0882-4010(92)90019-K  0.424
1991 Waltman WD, Gray BM, Svanborg C, Facklam R, Briles DE. Epidemiologic studies of group 9 pneumococci in terms of protein type and 9N versus 9V capsular type. The Journal of Infectious Diseases. 163: 812-8. PMID 2010634 DOI: 10.1093/Infdis/163.4.812  0.456
1991 Talkington DF, Crimmins DL, Voellinger DC, Yother J, Briles DE. A 43-kilodalton pneumococcal surface protein, PspA: Isolation, protective abilities, and structural analysis of the amino-terminal sequence Infection and Immunity. 59: 1285-1289. PMID 2004810 DOI: 10.1128/Iai.59.4.1285-1289.1991  0.762
1991 McDaniel LS, Sheffield JS, Delucchi P, Briles DE. PspA, a surface protein of Streptococcus pneumonia, is capable of eliciting protection against pneumococci of more than one capsular type Infection and Immunity. 59: 222-228. PMID 1987036 DOI: 10.1128/Iai.59.1.222-228.1991  0.6
1991 Benjamin WH, Yother J, Hall P, Briles DE. The Salmonella typhimurium locus mviA regulates virulence in Itys but not Ityr mice: Functional mviA results in avirulence; mutant (nonfunctional) mviA results in virulence Journal of Experimental Medicine. 174: 1073-1083. PMID 1940789 DOI: 10.1084/Jem.174.5.1073  0.725
1991 Dunlap NE, Benjamin WH, McCall RD, Tilden AB, Briles DE. A 'safe-site' for Salmonella typhimurium is within splenic cells during the early phase of infection in mice Microbial Pathogenesis. 10: 297-310. PMID 1895929 DOI: 10.1016/0882-4010(91)90013-Z  0.486
1991 Fallon MT, Benjamin WH, Schoeb TR, Briles DE. Mouse hepatitis virus strain UAB infection enhances resistance to Salmonella typhimurium in mice by inducing suppression of bacterial growth Infection and Immunity. 59: 852-856. PMID 1847697 DOI: 10.1128/Iai.59.3.852-856.1991  0.5
1991 Vakil M, Briles DE, Kearney JF. Antigen-Independent Selection of T15 Idiotype During B-Cell Ontogeny in Mice Developmental Immunology. 1: 203-212. PMID 1821697 DOI: 10.1155/1991/45352  0.473
1991 Benjamin WH, Hall P, Briles DE. A hemA mutation renders Salmonella typhimurium avirulent in mice, yet capable of eliciting protection against intravenous infection with S. typhimurium Microbial Pathogenesis. 11: 289-295. PMID 1813780 DOI: 10.1016/0882-4010(91)90033-7  0.532
1990 Waltman WD, McDaniel LS, Gray BM, Briles DE. Variation in the molecular weight of PspA (pneumococcal surface protein A) among Streptococcus pneumoniae. Microbial Pathogenesis. 8: 61-9. PMID 2333033 DOI: 10.1016/0882-4010(90)90008-E  0.487
1990 Benjamin WH, Hall P, Roberts SJ, Briles DE. The primary effect of the Ity locus is on the rate of growth of Salmonella typhimurium that are relatively protected from killing Journal of Immunology. 144: 3143-3151. PMID 2182715  0.396
1990 Crain MJ, Waltman WD, Turner JS, Yother J, Talkington DF, McDaniel LS, Gray BM, Briles DE. Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae. Infection and Immunity. 58: 3293-9. PMID 1698178 DOI: 10.1128/Iai.58.10.3293-3299.1990  0.754
1989 Nordenstam G, Andersson B, Bengtsson C, Briles D, Scott G, Svanborg A, Edén CS. Age-Related Change In Anti-Carbohydrate Antibody Levels American Journal of Epidemiology. 129: 89-96. PMID 2910075 DOI: 10.1093/Oxfordjournals.Aje.A115127  0.416
1989 Marion TN, Bothwell ALM, Briles DE, Janeway CA. IgG anti-DNA autoantibodies within an individual autoimmune mouse are the products of clonal selection Journal of Immunology. 142: 4269-4274. PMID 2786025  0.376
1989 Berry AM, Yother J, Briles DE, Hansman D, Paton JC. Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae Infection and Immunity. 57: 2037-2042. PMID 2731982 DOI: 10.1128/Iai.57.7.2037-2042.1989  0.721
1989 Briles DE, Forman C, Horowitz JC, Volanakis JE, Benjamin WH, McDaniel LS, Eldridge J, Brooks J. Antipneumococcal effects of C-reactive protein and monoclonal antibodies to pneumococcal cell wall and capsular antigens. Infection and Immunity. 57: 1457-64. PMID 2707854 DOI: 10.1128/Iai.57.5.1457-1464.1989  0.535
1989 Fallon MT, Schoeb TR, Benjamin WH, Lindsey JR, Briles DE. Modulation of resistance to Salmonella typhimurium infection in mice by mouse hepatitis virus (MHV) Microbial Pathogenesis. 6: 81-91. PMID 2541308 DOI: 10.1016/0882-4010(89)90011-9  0.479
1989 Briles DE, Forman C, Horowitz JC, Volanakis JE, Benjamin WH, McDaniel LS, Eldridge J, Brooks J. Antipneumococcal effects of C-reactive protein and monoclonal antibodies to pneumococcal cell wall and capsular antigens. Infection and Immunity. 57: 1457-1464. DOI: 10.1128/iai.57.5.1457-1464.1989  0.378
1988 Scott MG, Shackelford PG, Briles DE, Nahm MH. Human IgG subclasses and their relation to carbohydrate antigen immunocompetence Diagnostic and Clinical Immunology. 5: 241-248. PMID 3282712  0.41
1988 Waltman WD, McDaniel LS, Andersson B, Bland L, Gray BM, Eden CS, Briles DE. Protein serotyping of Streptococcus pneumoniae based on reactivity to six monoclonal antibodies. Microbial Pathogenesis. 5: 159-67. PMID 3216776 DOI: 10.1016/0882-4010(88)90018-6  0.512
1988 Briles DE, Yother J, McDaniel LS. Role of pneumococcal surface protein A in the virulence of Streptococcus pneumoniae Reviews of Infectious Diseases. 10. PMID 3187321 DOI: 10.1093/Cid/10.Supplement_2.S372  0.789
1988 McDaniel LS, Briles DE. A pneumococcal surface protein (PspB) that exhibits the same protease sensitivity as streptococcal R antigen Infection and Immunity. 56: 3001-3003. PMID 3139568 DOI: 10.1128/Iai.56.11.3001-3003.1988  0.451
1988 Waltman WD, Gray B, McDaniel LS, Briles DE. Cross-reactive monoclonal antibodies for diagnosis of pneumococcal meningitis Journal of Clinical Microbiology. 26: 1635-1640. PMID 2460493 DOI: 10.1128/Jcm.26.9.1635-1640.1988  0.43
1987 Briles DE, Scott G, Gray B, Crain MJ, Blaese M, Nahm M, Scott V, Haber P. Naturally occurring antibodies to phosphocholine as a potential index of antibody responsiveness to polysaccharides. The Journal of Infectious Diseases. 155: 1307-14. PMID 3572041 DOI: 10.1093/Infdis/155.6.1307  0.446
1987 Scott MG, Briles DE, Shackelford PG, Smith DS, Nahm MH. Human antibodies to phosphocholine. IgG anti-PC antibodies express restricted numbers of V and C regions Journal of Immunology. 138: 3325-3331. PMID 3571975  0.348
1987 Horowitz J, Volanakis JE, Briles DE. Blood clearance of Streptococcus pneumoniae by C-reactive protein Journal of Immunology. 138: 2598-2603. PMID 3559209  0.439
1987 McDaniel LS, Yother J, Vijayakumar M, McGarry L, Guild WR, Briles DE. Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA) Journal of Experimental Medicine. 165: 381-394. PMID 3546575 DOI: 10.1084/Jem.165.2.381  0.779
1987 McDaniel LS, Waltman WD, Gray B, Briles DE. A protective monoclonal antibody that reacts with a novel antigen of pneumococcal teichoic acid Microbial Pathogenesis. 3: 249-260. PMID 2462151 DOI: 10.1016/0882-4010(87)90058-1  0.5
1987 Lal RB, Paranjape RS, Briles DE, Nutman TB, Ottesen EA. Circulating parasite antigen(s) in lymphatic filariasis: Use of monoclonal antibodies to phosphocholine for immunodiagnosis Journal of Immunology. 138: 3454-3460. PMID 2437195  0.397
1986 Nahm MH, Blaese RM, Crain MJ, Briles DE. Patients with Wiskott-Aldrich Syndrome have normal IgG2 levels Journal of Immunology. 137: 3484-3487. PMID 3782789  0.414
1986 Yother J, McDaniel LS, Briles DE. Transformation of encapsulated Streptococcus pneumoniae Journal of Bacteriology. 168: 1463-1465. PMID 3782044 DOI: 10.1128/Jb.168.3.1463-1465.1986  0.676
1986 Musher DM, Chapman AJ, Goree A, Jonsson S, Briles D, Baughn RE. Natural and vaccine-related immunity to Streptococcus pneumoniae. The Journal of Infectious Diseases. 154: 245-56. PMID 3722865 DOI: 10.1093/Infdis/154.2.245  0.518
1986 Benjamin WH, Posey BS, Briles DE. Effects of in vitro growth phase on the pathogenesis of Salmonella typhimurium in mice Journal of General Microbiology. 132: 1283-1295. PMID 3534136 DOI: 10.1099/00221287-132-5-1283  0.409
1986 Benjamin WH, Turnbough CL, Posey BS, Briles DE. Salmonella typhimurium virulence genes necessary to exploit the Ity(s/s) genotype of the mouse Infection and Immunity. 51: 872-878. PMID 3512437 DOI: 10.1128/Iai.51.3.872-878.1986  0.494
1986 McDaniel LS, Scott G, Widenhofer K, Carroll JM, Briles DE. Analysis of a surface protein of Streptococcus pneumoniae recognised by protective monoclonal antibodies. Microbial Pathogenesis. 1: 519-31. PMID 3508498 DOI: 10.1016/0882-4010(86)90038-0  0.527
1986 Benjamin WH, Turnbough CL, Goguen JD, Posey BS, Briles DE. Genetic mapping of novel virulence determinants of Salmonella typhimurium to the region between trpD and supD Microbial Pathogenesis. 1: 115-124. PMID 3334153 DOI: 10.1016/0882-4010(86)90014-8  0.684
1986 Briles DE, Benjamin W, Posey B, Michalek SM, McGhee JR. Independence of macrophage activation and expression of the alleles of the Ity (immunity to typhimurium) locus Microbial Pathogenesis. 1: 33-41. PMID 3150024 DOI: 10.1016/0882-4010(86)90029-X  0.397
1986 Briles DE, Benjamin WH, Huster WJ, Posey B. Genetic approaches to the study of disease resistance: with special emphasis on the use of recombinant inbred mice Current Topics in Microbiology and Immunology. 124: 21-35. PMID 3086038 DOI: 10.1007/978-3-642-70986-9_2  0.407
1986 Briles DE, Horowitz J, McDaniel LS, Benjamin WH, Claflin JL, Booker CL, Scott G, Forman C. Genetic control of the susceptibility to pneumococcal infection. Current Topics in Microbiology and Immunology. 124: 103-20. PMID 3086036 DOI: 10.1007/978-3-642-70986-9_7  0.483
1985 Briles DE, Kearney JF. Antiidiotypic antibodies Methods in Enzymology. 174-189. PMID 3937022 DOI: 10.1016/S0076-6879(85)16012-X  0.452
1985 Hagberg L, Briles DE, Eden CS. Evidence for separate genetic defects in C3H/HeJ and C3HeB/FeJ mice, that affect susceptibility to gram-negative infections Journal of Immunology. 134: 4118-4122. PMID 3886795  0.315
1985 Benjamin WH, Turnbough CL, Posey BS, Briles DE. The ability of Salmonella typhimurium to produce the siderophore enterobactin is not a virulence factor in mouse typhoid Infection and Immunity. 50: 392-397. PMID 2932389 DOI: 10.1128/Iai.50.2.392-397.1985  0.459
1985 Kearney JF, McCarthy MT, Stohrer R, Benjamin WH, Briles DE. Induction of germ-line anti-alpha 1-3 dextran antibody responses in mice by members of the Enterobacteriaceae family. Journal of Immunology (Baltimore, Md. : 1950). 135: 3468-72. PMID 2413122  0.387
1985 Horowitz J, Volanakis JE, Briles DE. Blood clearance of pneumococci by C-reactive protein Federation Proceedings. 44.  0.264
1985 Kiyotaki M, Briles DE, Clement LT. Monoclonal antibodies against idiotopes on human anti-hapten antibodies Federation Proceedings. 44.  0.321
1984 McDaniel LS, Benjamin WH, Forman C, Briles DE. Blood clearance by anti-phosphocholine antibodies as a mechanism of protection in experimental pneumococcal bacteremia Journal of Immunology. 133: 3308-3312. PMID 6491288  0.413
1984 Conley ME, Briles DE. Lack of IgA subclass restriction in antibody response to phosphorylcholine, β lactoglobulin and tetanus toxoid Immunology. 53: 419-426. PMID 6490093  0.394
1984 Basta P, Briles DE. The mouse heavy chain variable region marker, J606-GAC, is not restricted to particular B cell isotypes or subsets Journal of Immunology. 132: 783-786. PMID 6418810  0.373
1984 McDaniel LS, Scott G, Kearney JF, Briles DE. Monoclonal antibodies against protease-sensitive pneumococcal antigens can protect mice from fatal infection with Streptococcus pneumoniae Journal of Experimental Medicine. 160: 386-397. PMID 6381634 DOI: 10.1084/Jem.160.2.386  0.532
1984 Edén CS, Briles D, Hagberg L, McGhee J, Michalec S. Genetic factors in host resistance to urinary tract infection Infection. 12: 118-122. PMID 6376364 DOI: 10.1007/Bf01641692  0.435
1984 Briles DE, Forman C, Hudak S, Claflin JL. The effects of subclass on the ability of anti-phosphocholine antibodies to protect mice from fatal infection with Streptococcus pneumoniae Journal of Molecular and Cellular Immunology. 1: 305-309. PMID 6336560  0.45
1984 Briles DE, Forman C, Hudak S, Claflin JL. The effects of idiotype on the ability of IgG1 anti-phosphorylcholine antibodies to protect mice from fatal infection with Streptococcus pneumniae European Journal of Immunology. 14: 1027-1030. PMID 6333985  0.395
1984 Colwell DE, Michalek SM, Briles DE, Jirillo E, McGhee JR. Monoclonal antibodies to Salmonella lipopolysaccharide: Anti-O-polysaccharide antibodies protect C3H mice against challenge with virulent Salmonella typhimurium Journal of Immunology. 133: 950-957. PMID 6203984  0.426
1984 Basta P, Griffin JA, Briles DE. The J606-GAC subset of antibody is composed of the products of several - different variable region gene segments Federation Proceedings. 43.  0.283
1984 McDaniel LS, Scott G, Svanborg Eden C, Briles DE. Monoclonal antibodies against surface polypeptides on mouse virulent strains of Streptococcus pneumoniae Federation Proceedings. 43.  0.436
1983 Wallick S, Claflin JL, Briles DE. Resistance to Streptococcus pneumoniae is induced by a phosphocholine-protein conjugate Journal of Immunology. 130: 2871-2875. PMID 6854020  0.467
1983 Gray BM, Dillon HC, Briles DE. Epidemiological studies of Streptococcus pneumoniae in infants: development of antibody to phosphocholine. Journal of Clinical Microbiology. 18: 1102-7. PMID 6643664 DOI: 10.1128/Jcm.18.5.1102-1107.1983  0.466
1983 Cooper MD, Haber P, Gathings WE, Mayumi M, Kuritani T, Briles DE. Deficient IgA synthesis viewed in the context of normal development of IgA B-cells Annals of the New York Academy of Sciences. 409: 461-468. PMID 6346996 DOI: 10.1111/J.1749-6632.1983.Tb26890.X  0.35
1983 Basta P, Kubagawa H, Kearney JF, Briles DE. Ten percent of normal B cells and plasma cells share A V(H) determinants) (J606-GAC) with a distinct subset of murine V(H)III plasmacytomas Journal of Immunology. 130: 2423-2428. PMID 6187856  0.333
1982 Marion TN, Lawton AR, Kearney JF, Briles DE. Anti-DNA autoantibodies in (NZB x NZW)F1 mice are clonally heterogeneous, but the majority share a common idiotype Journal of Immunology. 128: 668-674. PMID 7198664  0.344
1982 Briles DE, Forman C, Hudak S, Claflin JL. Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae Journal of Experimental Medicine. 156: 1177-1185. PMID 7153709 DOI: 10.1084/Jem.156.4.1177  0.464
1982 Yother J, Forman C, Gray BM, Briles DE. Protection of mice from infection with Streptococcus pneumoniae by anti-phosphocholine antibody. Infection and Immunity. 36: 184-8. PMID 7076292 DOI: 10.1128/Iai.36.1.184-188.1982  0.769
1982 Yother J, Volanakis JE, Briles DE. Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in mice Journal of Immunology. 128: 2374-2376. PMID 7061864  0.729
1982 Briles DE, Nahm M, Marion TN, Perlmutter RM, Davie JM. Streptococcal group A carbohydrate has properties of both a thymus-independent (TI-2) and a thymus-dependent antigen. Journal of Immunology (Baltimore, Md. : 1950). 128: 2032-5. PMID 7037958  0.399
1982 LeJeune JM, Briles DE, Lawton AR, Kearney JF. Estimate of the light chain repertoire size of fetal and adult BALB/cJ and CBA/J mice Journal of Immunology. 129: 673-677. PMID 6806379  0.28
1981 Briles DE, Nahm M, Schroer K, Davie J, Baker P, Kearney J, Barletta R. Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 Streptococcus pneumoniae Journal of Experimental Medicine. 153: 694-705. PMID 7252411 DOI: 10.1084/Jem.153.3.694  0.544
1981 Briles DE, Lehmeyer J, Forman C. Phagocytosis and killing of Salmonella typhimurium by peritoneal exudate cells Infection and Immunity. 33: 380-388. PMID 7024128 DOI: 10.1128/Iai.33.2.380-388.1981  0.456
1981 Briles DE, Carroll RJ. A simple method for estimating the probable numbers of different antibodies by examining the repeat frequencies of sequences or isoelectric focusing patterns Molecular Immunology. 18: 29-38. PMID 6790935 DOI: 10.1016/0161-5890(81)90045-6  0.4
1981 Briles DE, Benjamin WH, Williams CA, Davie JM. A genetic locus responsible for salmonella susceptibility in BSVS mice is not responsible for the limited T-dependent immune responsiveness of BSVS mice. Journal of Immunology (Baltimore, Md. : 1950). 127: 906-11. PMID 6790621  0.387
1981 Briles DE, Latham Claflin J, Schroer K, Forman C. Mouse IgG3 antibodies are highly protective against infection with Streptococcus pneumoniae Nature. 294: 88-90. PMID 6170000 DOI: 10.1038/294088A0  0.52
1980 Briles DE, Davie JM. Clonal nature of the immune response. II. The effect of immunization on clonal commitment. The Journal of Experimental Medicine. 152: 151-60. PMID 6995551 DOI: 10.1084/Jem.152.1.151  0.484
1980 Nicolotti RA, Briles DE, Schroer JA, Davie JM. Isoelectric focusing of immunoglobulins: improved methodology. Journal of Immunological Methods. 33: 101-15. PMID 6768804 DOI: 10.1016/S0022-1759(80)80001-9  0.446
1979 Briles DE, Perlmutter RM, Hansburg D, Little JR, Davie JM. Immune response deficiency of BSVS mice. II. Generalized deficiency to thymus-dependent antigens. European Journal of Immunology. 9: 255-61. PMID 89033 DOI: 10.1002/Eji.1830090402  0.503
1978 Hansburg D, Perlmutter RM, Briles DE, Davie JM. Analysis of the diversity of murine antibodies to dextran B1355. III. Idiotypic and spectrotypic correlations. European Journal of Immunology. 8: 352-9. PMID 689075 DOI: 10.1002/Eji.1830080512  0.441
1978 Perlmutter RM, Briles DE, Greve JM, Davie JM. Light chain diversity of murine anti-streptococcal antibodies: IgCH-linked effects on L chain expression. Journal of Immunology (Baltimore, Md. : 1950). 121: 149-58. PMID 97345  0.325
1978 Perlmutter RM, Hansburg D, Briles DE, Nicolotti RA, Davie JM. Subclass restriction of murine anti-carbohydrate antibodies. Journal of Immunology (Baltimore, Md. : 1950). 121: 566-72. PMID 79606  0.391
1977 Hansburg D, Briles DE, Davie JM. Analysis of the diversity of murine antibodies to dextran B1355. II. Demonstration of multiple idiotypes with variable expression in several strains. Journal of Immunology (Baltimore, Md. : 1950). 119: 1406-12. PMID 408420  0.403
1977 Perlmutter RM, Briles DE, Davie JM. Complete sharing of light chain spectrotypes by murine IgM and IgG anti-streptococcal antibodies. Journal of Immunology (Baltimore, Md. : 1950). 118: 2161-6. PMID 405425  0.349
1977 Briles DE, Krause RM, Davie JM. Immune response deficiency of BSVS mice - I. Identification of Ir gene differences between A/J and BSVS mice in the antistreptococcal group A carbohydrate response Immunogenetics. 4: 381-392. DOI: 10.1007/Bf01575676  0.718
1976 Hansburg D, Briles DE, Davie JM. Analysis of the diversity of murine antibodies to dextran B1355. I. Generation of a larger, pauci-clonal response by a bacterial vaccine. Journal of Immunology (Baltimore, Md. : 1950). 117: 569-75. PMID 59782  0.397
1975 Briles DE, Davie JM. Detection of isoelectric focused antibody by autoradiography and hemolysis of antigen-coated erythrocytes. A comparison of methods. Journal of Immunological Methods. 8: 363-72. PMID 1104713 DOI: 10.1016/0022-1759(75)90058-7  0.434
1975 Briles DE, Davie JM. Clonal dominance. I. Restricted nature of the IgM antibody response to group A streptococcal carbohydrate in mice Journal of Experimental Medicine. 141: 1291-1307. PMID 1092797 DOI: 10.1084/Jem.141.6.1291  0.505
1974 Briles DE, Krause RM. Mouse strain-specific idiotypy and interstrain idiotypic cross-reactions. Journal of Immunology (Baltimore, Md. : 1950). 113: 522-30. PMID 4858626  0.683
1974 Schroer KR, Briles DE, Van Boxel JA, Davie JM. Idiotypic uniformity of cell surface immunoglobulin in chronic lymphocytic leukemia. Evidence for monoclonal proliferation Journal of Experimental Medicine. 140: 1416-1420. PMID 4138880 DOI: 10.1084/Jem.140.5.1416  0.386
1974 Briles DE, Davie JM. Restriction of early IgM antibody response to streptococcal group A carbohydrate Federation Proceedings. 33: 3390.  0.317
1972 Briles DE, Krause RM. Mouse antibodies to group A streptococcal carbohydrate; use of idiotypy to detect inbred strain specificity and to monitor spleen cell transfer in syngenetic mice. Journal of Immunology (Baltimore, Md. : 1950). 109: 1311-20. PMID 5086237  0.726
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