Serpil C. Erzurum - Publications

Affiliations: 
Cleveland State University, Cleveland, OH, United States 
Area:
Cell Biology, Molecular Biology, Microbiology Biology

263 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sumi MP, Tupta B, Roychowdhury S, Comhair S, Asosingh K, Stuehr DJ, Erzurum SC, Ghosh A. Hemoglobin resident in the lung epithelium is protective for smooth muscle soluble guanylate cyclase function. Redox Biology. 63: 102717. PMID 37120930 DOI: 10.1016/j.redox.2023.102717  0.325
2022 Tattersall MC, Lee KE, Tsuchiya N, Osman F, Korcarz CE, Hansen KM, Peters MC, Fahy JV, Longhurst CA, Dunican E, Wentzel SE, Leader JK, Israel E, Levy BD, Castro M, ... Erzurum SC, et al. Skeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program (SARP). American Journal of Respiratory and Critical Care Medicine. PMID 36194556 DOI: 10.1164/rccm.202203-0597OC  0.325
2021 Asosingh K, Comhair S, Mavrakis L, Xu W, Horton D, Taylor I, Tkachenko S, Hu B, Erzurum S. Single-cell transcriptomic profile of human pulmonary artery endothelial cells in health and pulmonary arterial hypertension. Scientific Reports. 11: 14714. PMID 34282213 DOI: 10.1038/s41598-021-94163-y  0.315
2021 Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips BR, Wenzel SE, Fahy JV, Israel E, Bleecker ER, et al. Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program. American Journal of Respiratory and Critical Care Medicine. PMID 33545021 DOI: 10.1164/rccm.202009-3713OC  0.323
2020 Ghosh A, Koziol-White CJ, Jester WF, Erzurum SC, Asosingh K, Panettieri RA, Stuehr DJ. An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling. Redox Biology. 39: 101832. PMID 33360351 DOI: 10.1016/j.redox.2020.101832  0.336
2020 Denlinger LC, Phillips BR, Sorkness RL, Bleecker ER, Castro M, DeBoer MD, Fitzpatrick AM, Hastie AT, Gaffin JM, Moore WC, Peters MC, Peters SP, Phipatanakul W, Cardet JC, Erzurum SC, et al. Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate to Severe Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 33290668 DOI: 10.1164/rccm.202002-0454OC  0.301
2020 Li X, Christenson SA, Modena B, Li H, Busse WW, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Moore WC, et al. Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways. The Journal of Allergy and Clinical Immunology. PMID 32795586 DOI: 10.1016/J.Jaci.2020.07.030  0.349
2020 Peters MC, Sajuthi S, Deford P, Christenson S, Rios CL, Montgomery MT, Woodruff PG, Mauger DT, Erzurum SC, Johansson MW, Denlinger LC, Jarjour NN, Castro M, Hastie AT, Moore W, et al. COVID-19 Related Genes in Sputum Cells in Asthma: Relationship to Demographic Features and Corticosteroids. American Journal of Respiratory and Critical Care Medicine. PMID 32348692 DOI: 10.1164/Rccm.202003-0821Oc  0.395
2020 Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips B, Wenzel SE, Fahy JV, Israel E, Bleecker ER, et al. Baseline sputum eosinophil+neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) Cohort. The Journal of Allergy and Clinical Immunology. PMID 32032631 DOI: 10.1016/J.Jaci.2020.01.039  0.438
2020 Asosingh K, Lauruschkat CD, Alemagno M, Frimel M, Wanner N, Weiss K, Kessler S, Meyers DA, Bennett C, Xu W, Erzurum S. Arginine metabolic control of airway inflammation. Jci Insight. 5. PMID 31996482 DOI: 10.1172/Jci.Insight.127801  0.422
2020 Zein J, Gaston B, Bazeley P, DeBoer MD, Igo RP, Bleecker ER, Meyers D, Comhair S, Marozkina NV, Cotton C, Patel M, Alyamani M, Xu W, Busse WW, Calhoun WJ, ... ... Erzurum SC, et al. genotype identifies glucocorticoid responsiveness in severe asthma. Proceedings of the National Academy of Sciences of the United States of America. PMID 31932420 DOI: 10.1073/Pnas.1918819117  0.334
2020 McManus JM, Le THN, Min B, Asosingh K, Zein J, Erzurum S, Sharifi N. SAT-734 HSD3B1 Expression in the Human Immune System Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.617  0.389
2020 Fajt M, Nouraie SM, Wojcik R, Trudeau J, Bleecker E, Meyers D, Jarjour N, Denlinger L, Castro M, Bacharier L, Israel E, Levy B, Phipatanakul W, Fitzpatrick A, Erzurum S, et al. Age of Asthma Onset, not Severity, Predicts Environmental Allergy Clusters The Journal of Allergy and Clinical Immunology. 145. DOI: 10.1016/J.Jaci.2019.12.223  0.329
2019 Xu W, Comhair SAA, Chen R, Hu B, Hou Y, Zhou Y, Mavrakis LA, Janocha AJ, Li L, Zhang D, Willard BB, Asosingh K, Cheng F, Erzurum SC. Integrative proteomics and phosphoproteomics in pulmonary arterial hypertension. Scientific Reports. 9: 18623. PMID 31819116 DOI: 10.1038/S41598-019-55053-6  0.364
2019 Ross KR, Gupta R, DeBoer MD, Zein J, Phillips BR, Mauger DT, Li C, Myers RE, Phipatanakul W, Fitzpatrick AM, Ly NP, Bacharier LB, Jackson DJ, Celedón JC, Larkin A, ... ... Erzurum SC, et al. Severe asthma during childhood and adolescence: A longitudinal study. The Journal of Allergy and Clinical Immunology. PMID 31622688 DOI: 10.1016/J.Jaci.2019.09.030  0.368
2019 Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, et al. Development and Initial Validation of the Asthma Severity Scoring System (ASSESS). The Journal of Allergy and Clinical Immunology. PMID 31604088 DOI: 10.1016/J.Jaci.2019.09.018  0.378
2019 Li X, Hastie AT, Peters MC, Hawkins GA, Phipatanakul W, Li H, Moore WC, Busse WW, Castro M, Erzurum SC, Gaston B, Israel E, Jarjour NN, Levy BD, Wenzel SE, et al. Investigation of the relationship between IL-6 and type 2 biomarkers in severe asthma. The Journal of Allergy and Clinical Immunology. PMID 31513878 DOI: 10.1016/J.Jaci.2019.08.031  0.374
2019 Stephens OR, Weiss K, Frimel M, Rose JA, Sun Y, Asosingh K, Farha S, Highland KB, Naga Prasad SV, Erzurum SC. Interdependence of hypoxia and β-adrenergic receptor signaling in Pulmonary Arterial Hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31242023 DOI: 10.1152/Ajplung.00015.2019  0.344
2019 Weathington N, O'Brien ME, Radder JE, Whisenant TC, Bleecker ER, Busse WW, Erzurum SC, Gaston B, Jarjour NN, Meyers DA, Milosevic J, Tedrow JR, Trudeau JB, Wong HP, Wu W, et al. Bronchoalveolar Lavage Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications. American Journal of Respiratory and Critical Care Medicine. PMID 31161938 DOI: 10.1164/Rccm.201811-2221Oc  0.414
2019 Oliveira SDS, Chen J, Castellon M, Mao M, Usha Raj J, Comhair S, Erzurum S, Silva CLM, Machado RF, Bonini MG, Minshall RD. Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)-Dependent Pulmonary Arterial Hypertension. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA118312038. PMID 30943774 DOI: 10.1161/Atvbaha.118.312038  0.383
2019 Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, et al. Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 30888839 DOI: 10.1164/Rccm.201810-1869Oc  0.359
2019 Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, Fahy JV, Fitzpatrick AM, Gaston BM, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Meyers DA, et al. Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 30682261 DOI: 10.1164/Rccm.201808-1543Oc  0.323
2018 Cheong HI, Farha S, Park MM, Thomas JD, Saygin D, Comhair SAA, Sharp J, Highland KB, Tang WHW, Erzurum SC. Endothelial Phenotype Evoked by Low Dose Carvedilol in Pulmonary Hypertension. Frontiers in Cardiovascular Medicine. 5: 180. PMID 30619887 DOI: 10.3389/Fcvm.2018.00180  0.33
2018 Comhair SAA, Bochenek G, Baicker-McKee S, Wang Z, Stachura T, Sanak M, Hammel JP, Hazen SL, Erzurum SC, Nizankowska-Mogilnicka E. The utility of biomarkers in diagnosis of aspirin exacerbated respiratory disease. Respiratory Research. 19: 210. PMID 30376852 DOI: 10.1186/S12931-018-0909-6  0.403
2018 Sofer A, Lee S, Papangeli I, Adachi T, Hwangbo C, Comhair S, DaSilva-Jardine P, Kim J, Schwarz JJ, Erzurum SC, Chun HJ. Therapeutic Engagement of the HDAC IIA-MEF2 Axis Improves Experimental Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 30106596 DOI: 10.1164/Rccm.201805-0817Le  0.323
2018 Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, et al. Neutrophil cytoplasts induce T17 differentiation and skew inflammation toward neutrophilia in severe asthma. Science Immunology. 3. PMID 30076281 DOI: 10.1126/Sciimmunol.Aao4747  0.442
2018 Majors AK, Chakravarti R, Ruple LM, Leahy R, Stuehr DJ, Lauer M, Erzurum SC, Janocha A, Aronica MA. Nitric oxide alters hyaluronan deposition by airway smooth muscle cells. Plos One. 13: e0200074. PMID 29966020 DOI: 10.1371/Journal.Pone.0200074  0.421
2018 Asosingh K, Weiss K, Queisser K, Wanner N, Yin M, Aronica M, Erzurum S. Endothelial cells in the innate response to allergens and initiation of atopic asthma. The Journal of Clinical Investigation. PMID 29911993 DOI: 10.1172/Jci97720  0.451
2018 Reichard A, Wanner N, Stuehr E, Alemagno M, Weiss K, Queisser K, Erzurum S, Asosingh K. Quantification of airway fibrosis in asthma by flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 93: 952-958. PMID 29659138 DOI: 10.1002/Cyto.A.23373  0.431
2018 DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, et al. Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. Bmc Pulmonary Medicine. 18: 58. PMID 29631584 DOI: 10.1186/S12890-018-0612-X  0.369
2018 Peters MC, Kerr S, Dunican EM, Woodruff PG, Fajt ML, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, et al. Refractory Airway Type-2 Inflammation in a Large Subgroup of Asthmatics treated with Inhaled Corticosteroids. The Journal of Allergy and Clinical Immunology. PMID 29524537 DOI: 10.1016/J.Jaci.2017.12.1009  0.383
2018 Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, ... Erzurum SC, et al. Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of Clinical Investigation. PMID 29400693 DOI: 10.1172/Jci95693  0.419
2018 Fajt ML, Peters M, Bleecker ER, Cardet JC, Castro M, Comhair S, Coverstone A, Denlinger LC, Erzurum SC, Hastie AT, Israel E, Jarjour NN, Johansson MW, Levy BD, Mauger DM, et al. Sputum Mast Cells and Eosinophils Identify Asthmatics with Lower Lung Function and Proneness to Exacerbations Journal of Allergy and Clinical Immunology. 141: AB196. DOI: 10.1016/J.Jaci.2017.12.621  0.401
2018 Ilges DT, Zhou L, Hall C, Sood S, Kozlowski J, Goss C, Cahill KN, Cui J, Crosby-Thompson A, Jarjour NN, DiMango E, Erzurum SC, Trevor JL, Wechsler ME, Boyce JA, et al. KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma - Impact on Airway Remodeling measured by MDCT Journal of Allergy and Clinical Immunology. 141: AB11. DOI: 10.1016/J.Jaci.2017.12.035  0.398
2017 Asosingh K, Wanner N, Weiss K, Queisser K, Gebreab L, Kassa B, Stuehr E, Graham B, Erzurum S. Bone marrow transplantation prevents right ventricle disease in the caveolin-1-deficient mouse model of pulmonary hypertension. Blood Advances. 1: 526-534. PMID 29296972 DOI: 10.1182/Bloodadvances.2016002691  0.352
2017 Asosingh K, Erzurum S. Mechanisms of right heart disease in pulmonary hypertension (2017 Grover Conference Series). Pulmonary Circulation. 8: 2045893217753121. PMID 29264954 DOI: 10.1177/2045893217753121  0.309
2017 Allawzi AM, Vang A, Clements RT, Jhun BS, Kue NR, Mancini TJ, Landi AK, Terentyev D, O-Uchi J, Comhair SA, Erzurum SC, Choudhary G. Activation of Anoctamin-1 Limits Pulmonary Endothelial Cell Proliferation via p38-MAPK-dependent Apoptosis. American Journal of Respiratory Cell and Molecular Biology. PMID 29100477 DOI: 10.1165/Rcmb.2016-0344Oc  0.391
2017 Hemnes AR, Beck GJ, Newman JH, Abidov A, Aldred MA, Barnard J, Berman Rosenzweig E, Borlaug BA, Chung WK, Comhair SAA, Erzurum SC, Frantz RP, Gray MP, Grunig G, Hassoun PM, et al. PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics. Circulation Research. 121: 1136-1139. PMID 29074534 DOI: 10.1161/Circresaha.117.311737  0.362
2017 Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, ... ... Erzurum SC, et al. Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. The Journal of Allergy and Clinical Immunology. in Practice. PMID 28866107 DOI: 10.1016/J.Jaip.2017.05.032  0.363
2017 Husta BC, Raoof S, Erzurum S, Mehta AC. Tracheobronchopathy from Inhaled Corticosteroids. Chest. PMID 28864055 DOI: 10.1016/J.Chest.2017.08.013  0.365
2017 Xu W, Comhair SAA, Janocha AJ, Lara A, Mavrakis LA, Bennett CD, Kalhan SC, Erzurum SC. Arginine metabolic endotypes related to asthma severity. Plos One. 12: e0183066. PMID 28797075 DOI: 10.1371/Journal.Pone.0183066  0.394
2017 Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, et al. Natural killer cell-mediated inflammation resolution is disabled in severe asthma. Science Immunology. 2. PMID 28783702 DOI: 10.1126/Sciimmunol.Aam5446  0.42
2017 Janocha AJ, Comhair SAA, Basnyat B, Neupane M, Gebremedhin A, Khan A, Ricci KS, Zhang R, Erzurum SC, Beall CM. Antioxidant defense and oxidative damage vary widely among high-altitude residents. American Journal of Human Biology : the Official Journal of the Human Biology Council. PMID 28726295 DOI: 10.1002/Ajhb.23039  0.301
2017 Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, et al. ALX receptor ligands define a biochemical endotype for severe asthma. Jci Insight. 2. PMID 28724795 DOI: 10.1172/Jci.Insight.93534  0.337
2017 Drake KM, Federici C, Duong HT, Comhair SA, Erzurum SC, Asosingh K, Aldred MA. Genomic stability of pulmonary artery endothelial colony-forming cells in culture. Pulmonary Circulation. 7: 421-427. PMID 28597778 DOI: 10.1177/2045893217700901  0.366
2017 Zein JG, Love TE, Erzurum SC. Asthma is Associated with a Lower Risk of Sepsis and Sepsis Related Mortality. American Journal of Respiratory and Critical Care Medicine. PMID 28530491 DOI: 10.1164/Rccm.201608-1583Le  0.322
2017 Cahill KN, Katz HR, Cui J, Lai J, Kazani S, Crosby-Thompson A, Garofalo D, Castro M, Jarjour N, DiMango E, Erzurum S, Trevor JL, Shenoy K, Chinchilli VM, Wechsler ME, et al. KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma. The New England Journal of Medicine. 376: 1911-1920. PMID 28514613 DOI: 10.1056/Nejmoa1613125  0.422
2017 Newman JH, Rich S, Abman SH, Alexander JH, Barnard J, Beck GJ, Benza RL, Bull TM, Chan SY, Chun HJ, Doogan D, Dupuis J, Erzurum SC, Frantz RP, Geraci M, et al. Enhancing Insights into Pulmonary Vascular Disease (PVD) Through a Precision Medicine Approach. A Joint NHLBI-CMREF Workshop Report. American Journal of Respiratory and Critical Care Medicine. PMID 28430547 DOI: 10.1164/Rccm.201701-0150Ws  0.365
2017 Hwangbo C, Lee HW, Kang H, Ju H, Wiley DS, Papangeli I, Han J, Kim JD, Dunworth WP, Hu X, Lee S, El-Hely O, Sofer A, Pak B, Peterson L, ... ... Erzurum SC, et al. Modulation of Endothelial BMPR2 Activity by VEGFR3 in Pulmonary Arterial Hypertension. Circulation. PMID 28356442 DOI: 10.1161/Circulationaha.116.025390  0.38
2017 Kartha GK, Li I, Comhair S, Erzurum SC, Monga M. Co-Occurrence of Asthma and Nephrolithiasis in Children. Plos One. 12: e0168813. PMID 28081237 DOI: 10.1371/Journal.Pone.0168813  0.392
2017 Ketelaar ME, Van De Kant K, Dijk FN, Klaassen EMM, Grotenboer N, Nawijn MC, Dompeling E, Koppelman GH, Murray C, Foden P, Lowe L, Durrington H, Custovic A, Simpson A, Simpson AJ, ... ... Erzurum S, et al. Abstracts from the 3rd International Severe Asthma Forum (ISAF) Clinical and Translational Allergy. 7. DOI: 10.1186/S13601-017-0149-8  0.391
2017 Cahill KN, Katz H, Cui J, Lai J, Kazani S, Crosby-Thompson A, Garofalo D, Castro M, Jarjour NN, DiMango E, Erzurum SC, Trevor JL, Shenoy K, Chinchilli VM, Wechsler ME, et al. Effect of KIT Inhibition by Imatinib on Airway Mast Cells in Patients with Severe Refractory Asthma (KIA) Journal of Allergy and Clinical Immunology. 139: AB169. DOI: 10.1016/J.Jaci.2016.12.553  0.42
2016 Modena BD, Bleecker ER, Busse WW, Erzurum SC, Gaston BM, Jarjour NN, Meyers DA, Milosevic J, Tedrow JR, Wu W, Kaminski N, Wenzel SE. Gene Expression Correlated to Severe Asthma Characteristics Reveals Heterogeneous Mechanisms of Severe Disease. American Journal of Respiratory and Critical Care Medicine. PMID 27984699 DOI: 10.1164/Rccm.201607-1407Oc  0.4
2016 Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy J, ... ... Erzurum SC, et al. Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 27967215 DOI: 10.1164/Rccm.201607-1453Oc  0.401
2016 Wang Z, DiDonato JA, Buffa JA, Comhair SA, Aronica MA, Dweik R, Lee NA, Lee JJ, Thomassen MJ, Kavuru M, Erzurum SC, Hazen SL. Eosinophil Peroxidase Catalyzed Protein Carbamylation Participates in Asthma. The Journal of Biological Chemistry. PMID 27587397 DOI: 10.1074/Jbc.M116.750034  0.423
2016 Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, ... Erzurum SC, et al. Inflammatory and Co-Morbid Features of Patients with Severe Asthma and Frequent Exacerbations. American Journal of Respiratory and Critical Care Medicine. PMID 27556234 DOI: 10.1164/Rccm.201602-0419Oc  0.397
2016 Asosingh K, Farha S, Erzurum SC. Myeloid Targets for Pulmonary Arterial Hypertension: Time for Another Look. American Journal of Respiratory and Critical Care Medicine. 194: 384. PMID 27479064 DOI: 10.1164/Rccm.201603-0465Le  0.319
2016 Panchabhai TS, Mukhopadhyay S, Sehgal S, Bandyopadhyay D, Erzurum SC, Mehta AC. Plugs of the Air Passages: A Clinicopathologic Review. Chest. PMID 27445091 DOI: 10.1016/J.Chest.2016.07.003  0.402
2016 Liu F, Haeger CM, Dieffenbach PB, Sicard D, Chrobak I, Coronata AM, Suárez Velandia MM, Vitali S, Colas RA, Norris PC, Marinković A, Liu X, Ma J, Rose CD, Lee SJ, ... ... Erzurum SC, et al. Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension. Jci Insight. 1. PMID 27347562 DOI: 10.1172/Jci.Insight.86987  0.368
2016 Zein JG, Udeh BL, Teague WG, Koroukian SM, Schlitz NK, Bleecker ER, Busse WB, Calhoun WJ, Castro M, Comhair SA, Fitzpatrick AM, Israel E, Wenzel SE, Holguin F, Gaston BM, ... Erzurum SC, et al. Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012. Plos One. 11: e0157301. PMID 27294365 DOI: 10.1371/Journal.Pone.0157301  0.343
2016 Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, et al. Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts. The Lancet. Respiratory Medicine. PMID 27283230 DOI: 10.1016/S2213-2600(16)30048-0  0.394
2016 Rose JA, Wanner N, Cheong HI, Queisser K, Barrett P, Park M, Hite C, Naga Prasad SV, Erzurum S, Asosingh K. Flow Cytometric Quantification of Peripheral Blood Cell β-Adrenergic Receptor Density and Urinary Endothelial Cell-Derived Microparticles in Pulmonary Arterial Hypertension. Plos One. 11: e0156940. PMID 27270458 DOI: 10.1371/Journal.Pone.0156940  0.351
2016 Farha S, Hu B, Comhair S, Zein J, Dweik R, Erzurum SC, Aldred MA. Mitochondrial Haplogroups and Risk of Pulmonary Arterial Hypertension. Plos One. 11: e0156042. PMID 27224443 DOI: 10.1371/Journal.Pone.0156042  0.342
2016 Xu W, Ghosh S, Comhair SA, Asosingh K, Janocha AJ, Mavrakis DA, Bennett CD, Gruca LL, Graham BB, Queisser KA, Kao CC, Wedes SH, Petrich JM, Tuder RM, Kalhan SC, ... Erzurum SC, et al. Increased mitochondrial arginine metabolism supports bioenergetics in asthma. The Journal of Clinical Investigation. PMID 27214549 DOI: 10.1172/Jci82925  0.441
2016 Ghosh S, Gupta MK, Xu W, Mavrakis DA, Janocha AJ, Comhair SA, Haque MM, Stuehr DJ, Yu J, Polgar P, Naga Prasad SV, Erzurum SC. Phosphorylation inactivation of endothelial nitric oxide synthesis in pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00092.2016. PMID 27130529 DOI: 10.1152/Ajplung.00092.2016  0.409
2016 Ghosh A, Koziol-White CJ, Asosingh K, Cheng G, Ruple L, Groneberg D, Friebe A, Comhair SA, Stasch JP, Panettieri RA, Aronica MA, Erzurum SC, Stuehr DJ. Soluble guanylate cyclase as an alternative target for bronchodilator therapy in asthma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27071111 DOI: 10.1073/Pnas.1524398113  0.469
2016 Li X, Hawkins GA, Moore WC, Hastie AT, Ampleford EJ, Milosevic J, Li H, Busse WW, Erzurum SC, Kaminski N, Wenzel SE, Bleecker ER, Meyers DA. Expression of asthma susceptibility genes in bronchial epithelial cells and bronchial alveolar lavage in the Severe Asthma Research Program (SARP) cohort. The Journal of Asthma : Official Journal of the Association For the Care of Asthma. 0. PMID 27050946 DOI: 10.3109/02770903.2016.1158268  0.405
2016 Erzurum SC. New Insights in Oxidant Biology in Asthma. Annals of the American Thoracic Society. 13: S35-9. PMID 27027950 DOI: 10.1513/Annalsats.201506-385Mg  0.438
2016 Asosingh K, Vasanji A, Tipton A, Queisser K, Wanner N, Janocha A, Grandon D, Anand-Apte B, Rothenberg ME, Dweik R, Erzurum SC. Eotaxin-Rich Proangiogenic Hematopoietic Progenitor Cells and CCR3+ Endothelium in the Atopic Asthmatic Response. Journal of Immunology (Baltimore, Md. : 1950). PMID 26810221 DOI: 10.4049/Jimmunol.1500770  0.452
2016 Moore W, Li X, Li H, Castro M, Erzurum S, Fahy J, Israel E, Jarjour N, Levy B, Bacharier L, Fitzpatrick A, Gaston B, Ly N, Myers R, Ramratnam S, et al. Reproducibility and stability of severe asthma research program (SARP) clinical cluster phenotypes in SARP3 European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa3033  0.346
2016 Park MM, Uzunaslan D, Chirakarnjanakorn S, Roach EC, Highland KB, Farha S, Erzurum S, Thomas J, Jellis C, Neumann D, DiFilippo F, Tang WW. RIGHT VENTRICULAR FDG-PET UPTAKE SUGGESTS A SHIFT TO GLYCOLYTIC METABOLISM IN THE SETTING OF RIGHT VENTRICULAR DYSFUNCTION RELATED TO PULMONARY ARTERIAL HYPERTENSION Journal of the American College of Cardiology. 67: 2052. DOI: 10.1016/S0735-1097(16)32053-8  0.326
2015 Riley CM, Wenzel SE, Castro M, Erzurum SC, Chung KF, Fitzpatrick AM, Gaston B, Israel E, Moore WC, Bleecker ER, Calhoun WJ, Jarjour NN, Busse WW, Peters SP, Teague WG, et al. Clinical Implications of Having Reduced Mid Forced Expiratory Flow Rates (FEF25-75), Independently of FEV1, in Adult Patients with Asthma. Plos One. 10: e0145476. PMID 26717486 DOI: 10.1371/Journal.Pone.0145476  0.311
2015 Hoffman SM, Chapman DG, Lahue KG, Cahoon JM, Rattu GK, Daphtary N, Aliyeva M, Fortner KA, Erzurum SC, Comhair SA, Woodruff PG, Bhakta N, Dixon AE, Irvin CG, Janssen-Heininger YM, et al. Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness. The Journal of Allergy and Clinical Immunology. PMID 26435004 DOI: 10.1016/J.Jaci.2015.08.018  0.413
2015 Park JH, Kusunose K, Kwon DH, Park MM, Erzurum SC, Thomas JD, Grimm RA, Griffin BP, Marwick TH, Popović ZB. Relationship between Right Ventricular Longitudinal Strain, Invasive Hemodynamics, and Functional Assessment in Pulmonary Arterial Hypertension. Korean Circulation Journal. 45: 398-407. PMID 26413108 DOI: 10.4070/Kcj.2015.45.5.398  0.302
2015 Zein JG, Menegay MC, Singer ME, Erzurum SC, Gildea TR, Cicenia JC, Khatri S, Castro M, Udeh BL. Cost effectiveness of bronchial thermoplasty in patients with severe uncontrolled asthma. The Journal of Asthma : Official Journal of the Association For the Care of Asthma. 1-7. PMID 26377375 DOI: 10.3109/02770903.2015.1072552  0.381
2015 Lauer ME, Majors AK, Comhair S, Ruple LM, Matuska B, Subramanian A, Farver C, Dworski R, Grandon D, Laskowski D, Dweik RA, Erzurum SC, Hascall VC, Aronica MA. Hyaluronan and Its Heavy Chain Modification in Asthma Severity and Experimental Asthma Exacerbation. The Journal of Biological Chemistry. 290: 23124-34. PMID 26209637 DOI: 10.1074/jbc.M115.663823  0.323
2015 Zein JG, Dweik RA, Comhair SA, Bleecker ER, Moore WC, Peters SP, Busse WW, Jarjour NN, Calhoun WJ, Castro M, Chung KF, Fitzpatrick A, Israel E, Teague WG, Wenzel SE, ... ... Erzurum SC, et al. Asthma Is More Severe in Older Adults. Plos One. 10: e0133490. PMID 26200463 DOI: 10.1371/Journal.Pone.0133490  0.385
2015 Xu W, Cardenes N, Corey C, Erzurum SC, Shiva S. Platelets from Asthmatic Individuals Show Less Reliance on Glycolysis. Plos One. 10: e0132007. PMID 26147848 DOI: 10.1371/Journal.Pone.0132007  0.432
2015 Zein JG, Erzurum SC. Asthma is Different in Women. Current Allergy and Asthma Reports. 15: 28. PMID 26141573 DOI: 10.1007/S11882-015-0528-Y  0.376
2015 Li X, Hastie AT, Hawkins GA, Moore WC, Ampleford EJ, Milosevic J, Li H, Busse WW, Erzurum SC, Kaminski N, Wenzel SE, Meyers DA, Bleecker ER. eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes. Allergy. PMID 26119467 DOI: 10.1111/All.12683  0.36
2015 Comhair SA, Grandon D, Khan A, Zhang R, Hazen SL, Erzurum SC. Coenzyme Q in asthma. American Journal of Respiratory and Critical Care Medicine. 191: 1336-8. PMID 26029840 DOI: 10.1164/Rccm.201412-2259Le  0.433
2015 Marozkina NV, Wang XQ, Stsiapura V, Fitzpatrick A, Carraro S, Hawkins GA, Bleecker E, Meyers D, Jarjour N, Fain SB, Wenzel S, Busse W, Castro M, Panettieri RA, Moore W, ... ... Erzurum S, et al. Erratum. Phenotype of asthmatics with increased airway S-nitrosoglutathione reductase activity. The European Respiratory Journal. 45: 1763. PMID 26028625 DOI: 10.1183/09031936.50042414  0.362
2015 Gupta MK, Asosingh K, Aronica M, Comhair S, Cao G, Erzurum S, Panettieri RA, Naga Prasad SV. Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe Asthma. Plos One. 10: e0125803. PMID 26023787 DOI: 10.1371/Journal.Pone.0125803  0.379
2015 Teodorescu M, Broytman O, Curran-Everett D, Sorkness RL, Crisafi G, Bleecker ER, Erzurum S, Gaston BM, Wenzel SE, Jarjour NN. Obstructive Sleep Apnea Risk, Asthma Burden, and Lower Airway Inflammation in Adults in the Severe Asthma Research Program (SARP) II. The Journal of Allergy and Clinical Immunology. in Practice. 3: 566-575.e1. PMID 26004304 DOI: 10.1016/J.Jaip.2015.04.002  0.359
2015 Kao CC, Wedes SH, Hsu JW, Bohren KM, Comhair SA, Jahoor F, Erzurum SC. Arginine metabolic endotypes in pulmonary arterial hypertension. Pulmonary Circulation. 5: 124-34. PMID 25992277 DOI: 10.1086/679720  0.375
2015 Federici C, Drake KM, Rigelsky CM, McNelly LN, Meade SL, Comhair SA, Erzurum SC, Aldred MA. Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. 192: 219-28. PMID 25918951 DOI: 10.1164/Rccm.201411-2128Oc  0.391
2015 Haslip M, Dostanic I, Huang Y, Zhang Y, Russell KS, Jurczak MJ, Mannam P, Giordano F, Erzurum SC, Lee PJ. Endothelial uncoupling protein 2 regulates mitophagy and pulmonary hypertension during intermittent hypoxia. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1166-78. PMID 25814675 DOI: 10.1161/Atvbaha.114.304865  0.376
2015 Yuan S, Hollinger M, Lachowicz-Scroggins ME, Kerr SC, Dunican EM, Daniel BM, Ghosh S, Erzurum SC, Willard B, Hazen SL, Huang X, Carrington SD, Oscarson S, Fahy JV. Oxidation increases mucin polymer cross-links to stiffen airway mucus gels. Science Translational Medicine. 7: 276ra27. PMID 25717100 DOI: 10.1126/Scitranslmed.3010525  0.372
2015 Naples R, Laskowski D, McCarthy K, Mattox E, Comhair SA, Erzurum SC. Carboxyhemoglobin and methemoglobin in asthma. Lung. 193: 183-7. PMID 25680415 DOI: 10.1007/S00408-015-9686-X  0.418
2015 Roach EC, Park MM, Tang WH, Thomas JD, Asosingh K, Kalaycio M, Erzurum SC, Farha S. Impaired right ventricular-pulmonary vascular function in myeloproliferative neoplasms. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 34: 390-4. PMID 25638299 DOI: 10.1016/J.Healun.2014.09.009  0.374
2015 Cowan DC, Taylor DR, Peterson LE, Cowan JO, Palmay R, Williamson A, Hammel J, Erzurum SC, Hazen SL, Comhair SA. Biomarker-based asthma phenotypes of corticosteroid response. The Journal of Allergy and Clinical Immunology. 135: 877-83.e1. PMID 25488689 DOI: 10.1016/J.Jaci.2014.10.026  0.385
2015 Marozkina NV, Wang XQ, Stsiapura V, Fitzpatrick A, Carraro S, Hawkins GA, Bleecker E, Meyers D, Jarjour N, Fain SB, Wenzel S, Busse W, Castro M, Panettieri RA, Moore W, ... ... Erzurum S, et al. Phenotype of asthmatics with increased airway S-nitrosoglutathione reductase activity. The European Respiratory Journal. 45: 87-97. PMID 25359343 DOI: 10.1183/09031936.00042414  0.421
2015 Kim J, Hwangbo C, Hu X, Kang Y, Papangeli I, Mehrotra D, Park H, Ju H, McLean DL, Comhair SA, Erzurum SC, Chun HJ. Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension. Circulation. 131: 190-9. PMID 25336633 DOI: 10.1161/Circulationaha.114.013339  0.382
2015 Stuehr DJ, Ghosh A, Koziol-White CJ, Asosingh K, Cheng G, Ruple L, Rodgers J, Groneberg D, Friebe A, Stasch J, Panettieri RA, Aronical MA, Erzurum SC. sGC redox regulation and asthma Bmc Pharmacology and Toxicology. 16. DOI: 10.1186/2050-6511-16-S1-A26  0.465
2015 Kartha G, Comhair S, Monga M, Erzurum SC. PD51-09 HIGH PREVALENCE OF KIDNEY STONES IN PEDIATRIC PATIENTS WITH ASTHMA Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.1769  0.307
2015 Okamoto T, Wheeler D, Chakravarti R, Liu Q, Janocha A, Laskowski D, Quintini C, Stuehr D, Erzurum S, Dweik R, McCurry K. Treatment With Sodium Nitrite Improves the Pulmonary Function of Rejected Human Lungs in Cellular Ex Vivo Lung Perfusion Model The Journal of Heart and Lung Transplantation. 34: S139. DOI: 10.1016/J.Healun.2015.01.374  0.351
2015 Zein JG, Erzurum SC. Asthma in the elderly Current Geriatrics Reports. 4: 174-182. DOI: 10.1007/S13670-015-0124-Y  0.416
2014 Farha S, Dweik R, Rahaghi F, Benza R, Hassoun P, Frantz R, Torres F, Quinn DA, Comhair S, Erzurum S, Asosingh K. Imatinib in pulmonary arterial hypertension: c-Kit inhibition. Pulmonary Circulation. 4: 452-5. PMID 25621158 DOI: 10.1086/677359  0.362
2014 Modena BD, Tedrow JR, Milosevic J, Bleecker ER, Meyers DA, Wu W, Bar-Joseph Z, Erzurum SC, Gaston BM, Busse WW, Jarjour NN, Kaminski N, Wenzel SE. Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways. American Journal of Respiratory and Critical Care Medicine. 190: 1363-72. PMID 25338189 DOI: 10.1164/Rccm.201406-1099Oc  0.411
2014 Sharma A, Janocha AJ, Hill BT, Smith MR, Erzurum SC, Almasan A. Targeting mTORC1-mediated metabolic addiction overcomes fludarabine resistance in malignant B cells. Molecular Cancer Research : McR. 12: 1205-15. PMID 25061101 DOI: 10.1158/1541-7786.Mcr-14-0124  0.311
2014 Fernandez-Bustamante A, Klawitter J, Repine JE, Agazio A, Janocha AJ, Shah C, Moss M, Douglas IS, Tran ZV, Erzurum SC, Christians U, Seres T. Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs. Anesthesiology. 121: 469-81. PMID 24809976 DOI: 10.1097/Sa.0000000000000162  0.336
2014 Busse WW, Erzurum SC, Blaisdell CJ, Noel P. Executive Summary: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Annals of the American Thoracic Society. 11: S123-4. PMID 24754820 DOI: 10.1513/Annalsats.201312-421Ld  0.346
2014 Ratanamaneechat S, Neumann DR, Difilippo FP, Comhair SA, Asosingh K, Ghosh S, Grandon D, Khan A, Aronica MA, Erzurum SC. Redox imaging of inflammation in asthma. American Journal of Respiratory and Critical Care Medicine. 189: 743-6. PMID 24628314 DOI: 10.1164/Rccm.201310-1872Le  0.46
2014 Xu W, Janocha AJ, Leahy RA, Klatte R, Dudzinski D, Mavrakis LA, Comhair SA, Lauer ME, Cotton CU, Erzurum SC. A novel method for pulmonary research: assessment of bioenergetic function at the air-liquid interface. Redox Biology. 2: 513-9. PMID 24624341 DOI: 10.1016/J.Redox.2014.01.004  0.378
2014 Ortega VE, Hawkins GA, Moore WC, Hastie AT, Ampleford EJ, Busse WW, Castro M, Chardon D, Erzurum SC, Israel E, Montealegre F, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Effect of rare variants in ADRB2 on risk of severe exacerbations and symptom control during longacting β agonist treatment in a multiethnic asthma population: a genetic study. The Lancet. Respiratory Medicine. 2: 204-13. PMID 24621682 DOI: 10.1016/S2213-2600(13)70289-3  0.309
2014 Wu W, Bleecker E, Moore W, Busse WW, Castro M, Chung KF, Calhoun WJ, Erzurum S, Gaston B, Israel E, Curran-Everett D, Wenzel SE. Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data. The Journal of Allergy and Clinical Immunology. 133: 1280-8. PMID 24589344 DOI: 10.1016/J.Jaci.2013.11.042  0.392
2014 Voraphani N, Gladwin MT, Contreras AU, Kaminski N, Tedrow JR, Milosevic J, Bleecker ER, Meyers DA, Ray A, Ray P, Erzurum SC, Busse WW, Zhao J, Trudeau JB, Wenzel SE. An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma. Mucosal Immunology. 7: 1175-85. PMID 24518246 DOI: 10.1038/Mi.2014.6  0.362
2014 Wysocki K, Park SY, Bleecker E, Busse W, Castro M, Chung KF, Gaston B, Erzurum S, Israel E, Teague WG, Moore CG, Wenzel S. Characterization of factors associated with systemic corticosteroid use in severe asthma: data from the Severe Asthma Research Program. The Journal of Allergy and Clinical Immunology. 133: 915-8. PMID 24332222 DOI: 10.1016/J.Jaci.2013.10.031  0.403
2014 Narula T, Farver C, Erzurum S, Aldred M, Lane C, Budev M, Akindipe O. Recurrence of Idiopathic Pulmonary Arterial Hypertension After Lung Transplantation Chest. 145: 624A. DOI: 10.1378/Chest.1826554  0.352
2014 Zein J, Comhair S, Bleecker E, Busse W, Calhoun W, Castro M, Chung KF, Dweik R, Fitzpatrick A, Gaston B, Israel E, Jarjour N, Moore W, Teague G, Wenzel S, ... Erzurum S, et al. The Effect of Aging and Menopause on Asthma Severity in Women Chest. 145: 22A. DOI: 10.1378/Chest.1783148  0.332
2014 Okamoto T, Wheeler D, Liu Q, Chakravarti R, Janocha A, Dan L, Cristiano Q, Stuehr D, Erzurum S, Dweik R, McCurry K. Pre-clinical treatment with sodium nitrite improves the pulmonary function of rejected human lungs in an ex vivo lung perfusion model Nitric Oxide. 42: 110. DOI: 10.1016/J.Niox.2014.09.036  0.346
2014 Majors A, Subramanian A, Ruple L, Chakravarti R, Comhair S, Leahy R, Erzurum S, Stuehr D, Aronica M. Nitric oxide alters hyaluronan deposition by cultured airway smooth muscle cells and correlates with hyaluronan levels in asthmatics Nitric Oxide. 42: 99. DOI: 10.1016/J.Niox.2014.09.007  0.344
2014 Hundal M, Cahill KN, Pedicini R, Crosby-Thompson A, Dutile S, Govindarajulu U, Shenoy K, Dransfield M, DiMango E, Erzurum SC, Castro M, Jarjour NN, Katz H, Boyce JA, Israel E. Bronchial Mast Cell Markers and Clinical Asthma Severity In Steroid Refractory Asthmatics Journal of Allergy and Clinical Immunology. 133: AB161. DOI: 10.1016/J.Jaci.2013.12.583  0.409
2013 Bakhshi FR, Mao M, Shajahan AN, Piegeler T, Chen Z, Chernaya O, Sharma T, Elliott WM, Szulcek R, Bogaard HJ, Comhair S, Erzurum S, van Nieuw Amerongen GP, Bonini MG, Minshall RD. Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertension. Pulmonary Circulation. 3: 816-30. PMID 25006397 DOI: 10.1086/674753  0.429
2013 Lanzola E, Farha S, Erzurum SC, Asosingh K. Bone marrow-derived vascular modulatory cells in pulmonary arterial hypertension. Pulmonary Circulation. 3: 781-91. PMID 25006394 DOI: 10.1086/674769  0.369
2013 Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW. Relevant issues in the pathology and pathobiology of pulmonary hypertension. Journal of the American College of Cardiology. 62: D4-12. PMID 24355640 DOI: 10.1016/J.Jacc.2013.10.025  0.374
2013 Wechsler ME, Laviolette M, Rubin AS, Fiterman J, Lapa e Silva JR, Shah PL, Fiss E, Olivenstein R, Thomson NC, Niven RM, Pavord ID, Simoff M, Hales JB, McEvoy C, Slebos DJ, ... ... Erzurum SC, et al. Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. The Journal of Allergy and Clinical Immunology. 132: 1295-302. PMID 23998657 DOI: 10.1016/J.Jaci.2013.08.009  0.39
2013 Patel M, Predescu D, Tandon R, Bardita C, Pogoriler J, Bhorade S, Wang M, Comhair S, Hemnes AR, Ryan-Hemnes A, Chen J, Machado R, Husain A, Erzurum S, Predescu S. A novel p38 mitogen-activated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension. The Journal of Biological Chemistry. 288: 25701-16. PMID 23893408 DOI: 10.1074/Jbc.M113.502674  0.4
2013 Rao CK, Moore CG, Bleecker E, Busse WW, Calhoun W, Castro M, Chung KF, Erzurum SC, Israel E, Curran-Everett D, Wenzel SE. Characteristics of perimenstrual asthma and its relation to asthma severity and control: data from the Severe Asthma Research Program. Chest. 143: 984-92. PMID 23632943 DOI: 10.1378/Chest.12-0973  0.415
2013 Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, et al. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. The Journal of Allergy and Clinical Immunology. 132: 313-20.e15. PMID 23541324 DOI: 10.1016/J.Jaci.2013.01.051  0.306
2013 Asosingh K, Cheng G, Xu W, Savasky BM, Aronica MA, Li X, Erzurum SC. Nascent endothelium initiates Th2 polarization of asthma. Journal of Immunology (Baltimore, Md. : 1950). 190: 3458-65. PMID 23427249 DOI: 10.4049/Jimmunol.1202095  0.438
2013 Ghelfi E, Yu CW, Elmasri H, Terwelp M, Lee CG, Bhandari V, Comhair SA, Erzurum SC, Hotamisligil GS, Elias JA, Cataltepe S. Fatty acid binding protein 4 regulates VEGF-induced airway angiogenesis and inflammation in a transgenic mouse model: implications for asthma. The American Journal of Pathology. 182: 1425-33. PMID 23391391 DOI: 10.1016/J.Ajpath.2012.12.009  0.408
2013 Kim J, Kang Y, Kojima Y, Lighthouse JK, Hu X, Aldred MA, McLean DL, Park H, Comhair SA, Greif DM, Erzurum SC, Chun HJ. An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension. Nature Medicine. 19: 74-82. PMID 23263626 DOI: 10.1038/Nm.3040  0.305
2013 Holguin F, Comhair SA, Hazen SL, Powers RW, Khatri SS, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Moore WC, Peters SP, ... ... Erzurum SC, et al. An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. American Journal of Respiratory and Critical Care Medicine. 187: 153-9. PMID 23204252 DOI: 10.1164/Rccm.201207-1270Oc  0.323
2013 Ghosh S, Willard B, Comhair SA, Dibello P, Xu W, Shiva S, Aulak KS, Kinter M, Erzurum SC. Disulfide bond as a switch for copper-zinc superoxide dismutase activity in asthma. Antioxidants & Redox Signaling. 18: 412-23. PMID 22867017 DOI: 10.1089/Ars.2012.4566  0.419
2013 Yu J, Taylor L, Wilson J, Comhair S, Erzurum S, Polgar P. Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension. Journal of Cellular Physiology. 228: 322-9. PMID 22688668 DOI: 10.1002/Jcp.24132  0.335
2013 Patel M, Predescu D, Tandon R, Bardita C, Pogoriler J, Bhorade S, Wang M, Comhair S, Ryan-Hemnes A, Chen J, Machado R, Husain A, Erzurum S, Predescu S. A novel p38 mitogen-activated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension. Journal of Biological Chemistry. 288: 36855-36855. DOI: 10.1074/Jbc.A113.502674  0.359
2013 Bakhshi FR, Shinin V, Mao M, Chen Z, Comhair S, Erzurum S, Bonini MG. P67 Nitric Oxide. 31: S42. DOI: 10.1016/J.Niox.2013.02.069  0.376
2013 Subramanian A, Majors A, Comhair SA, Erzurum SC, Aronica MA. Hyaluronan and Nitric Oxide Collaborate As Inflammatory Mediators in Asthma Journal of Allergy and Clinical Immunology. 131: AB44. DOI: 10.1016/J.Jaci.2012.12.840  0.397
2012 Ghosh S, Erzurum SC. Modulation of Asthma Pathogenesis by Nitric Oxide Pathways and Therapeutic Opportunities. Drug Discovery Today. Disease Mechanisms. 9: e89-e94. PMID 23976894 DOI: 10.1016/J.Ddmec.2012.10.004  0.439
2012 Bauer EM, Shapiro R, Zheng H, Ahmad F, Ishizawar D, Comhair SA, Erzurum SC, Billiar TR, Bauer PM. High mobility group box 1 contributes to the pathogenesis of experimental pulmonary hypertension via activation of Toll-like receptor 4. Molecular Medicine (Cambridge, Mass.). 18: 1509-18. PMID 23269975 DOI: 10.2119/Molmed.2012.00283  0.34
2012 Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O. Oxidative stress and antioxidant defense. The World Allergy Organization Journal. 5: 9-19. PMID 23268465 DOI: 10.1097/Wox.0B013E3182439613  0.355
2012 Farha S, Sharp J, Asosingh K, Park M, Comhair SA, Tang WH, Thomas J, Farver C, Hsieh F, Loyd JE, Erzurum SC. Mast cell number, phenotype, and function in human pulmonary arterial hypertension. Pulmonary Circulation. 2: 220-8. PMID 22837863 DOI: 10.4103/2045-8932.97609  0.445
2012 Asosingh K, Farha S, Lichtin A, Graham B, George D, Aldred M, Hazen SL, Loyd J, Tuder R, Erzurum SC. Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension. Blood. 120: 1218-27. PMID 22745307 DOI: 10.1182/Blood-2012-03-419275  0.353
2012 Torgerson DG, Capurso D, Ampleford EJ, Li X, Moore WC, Gignoux CR, Hu D, Eng C, Mathias RA, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, et al. Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects. The Journal of Allergy and Clinical Immunology. 130: 622-629.e9. PMID 22607992 DOI: 10.1016/J.Jaci.2012.03.045  0.318
2012 Hawkins GA, Robinson MB, Hastie AT, Li X, Li H, Moore WC, Howard TD, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma. The Journal of Allergy and Clinical Immunology. 130: 510-5.e1. PMID 22554704 DOI: 10.1016/J.Jaci.2012.03.018  0.314
2012 Wei L, Warburton RR, Preston IR, Roberts KE, Comhair SA, Erzurum SC, Hill NS, Fanburg BL. Serotonylated fibronectin is elevated in pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L1273-9. PMID 22523280 DOI: 10.1152/Ajplung.00082.2012  0.323
2012 Comhair SA, Xu W, Mavrakis L, Aldred MA, Asosingh K, Erzurum SC. Human primary lung endothelial cells in culture. American Journal of Respiratory Cell and Molecular Biology. 46: 723-30. PMID 22427538 DOI: 10.1165/Rcmb.2011-0416Te  0.411
2012 Szefler SJ, Wenzel S, Brown R, Erzurum SC, Fahy JV, Hamilton RG, Hunt JF, Kita H, Liu AH, Panettieri RA, Schleimer RP, Minnicozzi M. Asthma outcomes: biomarkers. The Journal of Allergy and Clinical Immunology. 129: S9-23. PMID 22386512 DOI: 10.1016/J.Jaci.2011.12.979  0.365
2012 Beall CM, Laskowski D, Erzurum SC. Nitric oxide in adaptation to altitude. Free Radical Biology & Medicine. 52: 1123-34. PMID 22300645 DOI: 10.1016/J.Freeradbiomed.2011.12.028  0.353
2012 Luyster FS, Teodorescu M, Bleecker E, Busse W, Calhoun W, Castro M, Chung KF, Erzurum S, Israel E, Strollo PJ, Wenzel SE. Sleep quality and asthma control and quality of life in non-severe and severe asthma. Sleep & Breathing = Schlaf & Atmung. 16: 1129-37. PMID 22102290 DOI: 10.1007/S11325-011-0616-8  0.328
2012 Jarjour NN, Erzurum SC, Bleecker ER, Calhoun WJ, Castro M, Comhair SA, Chung KF, Curran-Everett D, Dweik RA, Fain SB, Fitzpatrick AM, Gaston BM, Israel E, Hastie A, Hoffman EA, et al. Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program. American Journal of Respiratory and Critical Care Medicine. 185: 356-62. PMID 22095547 DOI: 10.1164/Rccm.201107-1317Pp  0.427
2012 Slager R, Moore W, Li H, Busse W, Castro M, Erzurum S, Fitzpatrick A, Wenzel S, Meyers D, Bleecker ER. 24 Common and Rare Variation in the T Helper 2 Gene Pathway Predicts Allergic Asthma Phenotypes World Allergy Organization Journal. 5: S8-S9. DOI: 10.1097/01.Wox.0000411769.14940.76  0.365
2011 Xu W, Erzurum SC. Endothelial cell energy metabolism, proliferation, and apoptosis in pulmonary hypertension. Comprehensive Physiology. 1: 357-72. PMID 23737177 DOI: 10.1002/Cphy.C090005  0.431
2011 Sahiner UM, Birben E, Erzurum S, Sackesen C, Kalayci O. Oxidative stress in asthma. The World Allergy Organization Journal. 4: 151-8. PMID 23268432 DOI: 10.1097/Wox.0B013E318232389E  0.427
2011 Duong HT, Comhair SA, Aldred MA, Mavrakis L, Savasky BM, Erzurum SC, Asosingh K. Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension. Pulmonary Circulation. 1: 475-86. PMID 22530103 DOI: 10.4103/2045-8932.93547  0.386
2011 Bauer EM, Zheng H, Comhair S, Erzurum S, Billiar TR, Bauer PM. Complement C3 deficiency attenuates chronic hypoxia-induced pulmonary hypertension in mice. Plos One. 6: e28578. PMID 22194859 DOI: 10.1371/Journal.Pone.0028578  0.335
2011 Janocha AJ, Koch CD, Tiso M, Ponchia A, Doctor A, Gibbons L, Gaston B, Beall CM, Erzurum SC. Nitric oxide during altitude acclimatization. The New England Journal of Medicine. 365: 1942-4. PMID 22087700 DOI: 10.1056/Nejmc1107887  0.304
2011 Drake KM, Zygmunt D, Mavrakis L, Harbor P, Wang L, Comhair SA, Erzurum SC, Aldred MA. Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8. American Journal of Respiratory and Critical Care Medicine. 184: 1400-8. PMID 21920918 DOI: 10.1164/Rccm.201106-1130Oc  0.327
2011 Dweik RA, Boggs PB, Erzurum SC, Irvin CG, Leigh MW, Lundberg JO, Olin AC, Plummer AL, Taylor DR. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. American Journal of Respiratory and Critical Care Medicine. 184: 602-15. PMID 21885636 DOI: 10.1164/Rccm.9120-11St  0.345
2011 Gangopahyay A, Oran M, Bauer EM, Wertz JW, Comhair SA, Erzurum SC, Bauer PM. Bone morphogenetic protein receptor II is a novel mediator of endothelial nitric-oxide synthase activation. The Journal of Biological Chemistry. 286: 33134-40. PMID 21808054 DOI: 10.1074/Jbc.M111.274100  0.357
2011 Duong HT, Erzurum SC, Asosingh K. Pro-angiogenic hematopoietic progenitor cells and endothelial colony-forming cells in pathological angiogenesis of bronchial and pulmonary circulation. Angiogenesis. 14: 411-22. PMID 21796417 DOI: 10.1007/S10456-011-9228-Y  0.449
2011 Dweik RA, Erzurum SC. Update on pulmonary vascular diseases 2010. American Journal of Respiratory and Critical Care Medicine. 184: 26-31. PMID 21737591 DOI: 10.1164/Rccm.201103-0394Up  0.354
2011 Ghosh S, Erzurum SC. Nitric oxide metabolism in asthma pathophysiology. Biochimica Et Biophysica Acta. 1810: 1008-16. PMID 21718755 DOI: 10.1016/J.Bbagen.2011.06.009  0.425
2011 Castro M, Fain SB, Hoffman EA, Gierada DS, Erzurum SC, Wenzel S. Lung imaging in asthmatic patients: the picture is clearer. The Journal of Allergy and Clinical Immunology. 128: 467-78. PMID 21636118 DOI: 10.1016/J.Jaci.2011.04.051  0.342
2011 Holguin F, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Moore WC, Peters SP, Yonas M, Teague WG, Wenzel SE. Obesity and asthma: an association modified by age of asthma onset. The Journal of Allergy and Clinical Immunology. 127: 1486-93.e2. PMID 21624618 DOI: 10.1016/J.Jaci.2011.03.036  0.369
2011 Comhair SA, Gaston BM, Ricci KS, Hammel J, Dweik RA, Teague WG, Meyers D, Ampleford EJ, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Israel E, ... ... Erzurum SC, et al. Detrimental effects of environmental tobacco smoke in relation to asthma severity. Plos One. 6: e18574. PMID 21572527 DOI: 10.1371/Journal.Pone.0018574  0.378
2011 Moore WC, Evans MD, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Curran-Everett D, Dweik RA, Gaston B, Hew M, Israel E, Mayse ML, Pascual RM, et al. Safety of investigative bronchoscopy in the Severe Asthma Research Program. The Journal of Allergy and Clinical Immunology. 128: 328-336.e3. PMID 21496892 DOI: 10.1016/J.Jaci.2011.02.042  0.429
2011 Li X, Howard TD, Moore WC, Ampleford EJ, Li H, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, et al. Importance of hedgehog interacting protein and other lung function genes in asthma. The Journal of Allergy and Clinical Immunology. 127: 1457-65. PMID 21397937 DOI: 10.1016/J.Jaci.2011.01.056  0.391
2011 Wedes SH, Wu W, Comhair SA, McDowell KM, DiDonato JA, Erzurum SC, Hazen SL. Urinary bromotyrosine measures asthma control and predicts asthma exacerbations in children. The Journal of Pediatrics. 159: 248-55.e1. PMID 21392781 DOI: 10.1016/J.Jpeds.2011.01.029  0.389
2011 Hoit BD, Dalton ND, Gebremedhin A, Janocha A, Zimmerman PA, Zimmerman AM, Strohl KP, Erzurum SC, Beall CM. Elevated pulmonary artery pressure among Amhara highlanders in Ethiopia. American Journal of Human Biology : the Official Journal of the Human Biology Council. 23: 168-76. PMID 21319245 DOI: 10.1002/Ajhb.21130  0.356
2011 Farha S, Asosingh K, Xu W, Sharp J, George D, Comhair S, Park M, Tang WH, Loyd JE, Theil K, Tubbs R, Hsi E, Lichtin A, Erzurum SC. Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities. Blood. 117: 3485-93. PMID 21258008 DOI: 10.1182/Blood-2010-09-306357  0.375
2011 Liu L, Teague WG, Erzurum S, Fitzpatrick A, Mantri S, Dweik RA, Bleecker ER, Meyers D, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Israel E, Jarjour WN, et al. Determinants of exhaled breath condensate pH in a large population with asthma. Chest. 139: 328-36. PMID 20966042 DOI: 10.1378/Chest.10-0163  0.376
2011 Balzar S, Fajt ML, Comhair SA, Erzurum SC, Bleecker E, Busse WW, Castro M, Gaston B, Israel E, Schwartz LB, Curran-Everett D, Moore CG, Wenzel SE. Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program. American Journal of Respiratory and Critical Care Medicine. 183: 299-309. PMID 20813890 DOI: 10.1164/Rccm.201002-0295Oc  0.413
2011 Harper Y, Asosingh K, Erzurum SC, Tang WHW. DEFICIENCY RATHER THAN MOBILIZATION OF CIRCULATING ENDOTHELIAL PROGENITOR CELLS IN SECONDARY PULMONARY HYPERTENSION Journal of the American College of Cardiology. 57: E1479. DOI: 10.1016/S0735-1097(11)61479-4  0.377
2011 Harper Y, Asosingh K, Anne C, Erzurum SC, Tang WW. Diminished Endothelial Progenitor Cells Were Associated with Endothelial Dysfunction in Patients with Pulmonary Hypertension Secondary to Left Heart Disease Journal of Cardiac Failure. 17: S27. DOI: 10.1016/J.Cardfail.2011.06.093  0.366
2010 Gamble C, Talbott E, Youk A, Holguin F, Pitt B, Silveira L, Bleecker E, Busse W, Calhoun W, Castro M, Chung KF, Erzurum S, Israel E, Wenzel S. Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program. The Journal of Allergy and Clinical Immunology. 126: 1149-56.e1. PMID 21051082 DOI: 10.1016/J.Jaci.2010.08.049  0.391
2010 Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, Asosingh K, Balaban R, Bauer N, Bhattacharya J, Bogaard H, Choudhary G, Dorn GW, Dweik R, Fagan K, et al. Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. American Journal of Respiratory and Critical Care Medicine. 182: 1554-62. PMID 20833821 DOI: 10.1164/Rccm.201006-0869Ws  0.355
2010 Brasier AR, Victor S, Ju H, Busse WW, Curran-Everett D, Bleecker E, Castro M, Chung KF, Gaston B, Israel E, Wenzel SE, Erzurum SC, Jarjour NN, Calhoun WJ. Predicting intermediate phenotypes in asthma using bronchoalveolar lavage-derived cytokines. Clinical and Translational Science. 3: 147-57. PMID 20718815 DOI: 10.1111/J.1752-8062.2010.00204.X  0.393
2010 Greenwald R, Fitzpatrick AM, Gaston B, Marozkina NV, Erzurum S, Teague WG. Breath formate is a marker of airway S-nitrosothiol depletion in severe asthma. Plos One. 5: e11919. PMID 20689836 DOI: 10.1371/Journal.Pone.0011919  0.43
2010 Aldred MA, Comhair SA, Varella-Garcia M, Asosingh K, Xu W, Noon GP, Thistlethwaite PA, Tuder RM, Erzurum SC, Geraci MW, Coldren CD. Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 182: 1153-60. PMID 20581168 DOI: 10.1164/Rccm.201003-0491Oc  0.37
2010 Asosingh K, Hanson JD, Cheng G, Aronica MA, Erzurum SC. Allergen-induced, eotaxin-rich, proangiogenic bone marrow progenitors: a blood-borne cellular envoy for lung eosinophilia. The Journal of Allergy and Clinical Immunology. 125: 918-25. PMID 20227754 DOI: 10.1016/J.Jaci.2010.01.017  0.364
2010 Dweik RA, Sorkness RL, Wenzel S, Hammel J, Curran-Everett D, Comhair SA, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Israel E, Jarjour N, Moore W, Peters S, ... ... Erzurum SC, et al. Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma. American Journal of Respiratory and Critical Care Medicine. 181: 1033-41. PMID 20133930 DOI: 10.1164/Rccm.200905-0695Oc  0.414
2010 Fijalkowska I, Xu W, Comhair SA, Janocha AJ, Mavrakis LA, Krishnamachary B, Zhen L, Mao T, Richter A, Erzurum SC, Tuder RM. Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells. The American Journal of Pathology. 176: 1130-8. PMID 20110409 DOI: 10.2353/Ajpath.2010.090832  0.376
2010 Castro M, Rubin AS, Laviolette M, Fiterman J, De Andrade Lima M, Shah PL, Fiss E, Olivenstein R, Thomson NC, Niven RM, Pavord ID, Simoff M, Duhamel DR, McEvoy C, Barbers R, ... ... Erzurum S, et al. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. American Journal of Respiratory and Critical Care Medicine. 181: 116-24. PMID 19815809 DOI: 10.1164/Rccm.200903-0354Oc  0.339
2010 Comhair SA, Erzurum SC. Redox control of asthma: molecular mechanisms and therapeutic opportunities. Antioxidants & Redox Signaling. 12: 93-124. PMID 19634987 DOI: 10.1089/Ars.2008.2425  0.438
2009 Wedes SH, Khatri SB, Zhang R, Wu W, Comhair SA, Wenzel S, Teague WG, Israel E, Erzurum SC, Hazen SL. Noninvasive markers of airway inflammation in asthma. Clinical and Translational Science. 2: 112-7. PMID 20234847 DOI: 10.1111/J.1752-8062.2009.00095.X  0.303
2009 Khatri SB, Holguin FC, Ryan PB, Mannino D, Erzurum SC, Teague WG. Association of ambient ozone exposure with airway inflammation and allergy in adults with asthma. The Journal of Asthma : Official Journal of the Association For the Care of Asthma. 46: 777-85. PMID 19863280 DOI: 10.1080/02770900902779284  0.314
2009 Asosingh K, Erzurum SC. Angioplasticity in asthma. Biochemical Society Transactions. 37: 805-10. PMID 19614598 DOI: 10.1042/Bst0370805  0.482
2009 Farha S, Asosingh K, Laskowski D, Hammel J, Dweik RA, Wiedemann HP, Erzurum SC. Effects of the menstrual cycle on lung function variables in women with asthma. American Journal of Respiratory and Critical Care Medicine. 180: 304-10. PMID 19520904 DOI: 10.1164/Rccm.200904-0497Oc  0.391
2009 Asosingh K, Erzurum SC, Yoder MC, Tuder RM. Letter by asosingh et Al regarding article, "circulating endothelial progenitor cells in patients with eisenmenger syndrome and idiopathic pulmonary arterial hypertension". Circulation. 119: e230; author reply e. PMID 19273727 DOI: 10.1161/Circulationaha.108.800961  0.348
2009 Chambellan A, Leahy R, Xu W, Cruickshank PJ, Janocha A, Szabo K, Cannady SB, Comhair SA, Erzurum SC. Pivotal role of c-Fos in nitric oxide synthase 2 expression in airway epithelial cells. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 20: 143-9. PMID 19135542 DOI: 10.1016/J.Niox.2008.12.004  0.34
2009 Lauer ME, Fulop C, Mukhopadhyay D, Comhair S, Erzurum SC, Hascall VC. Airway smooth muscle cells synthesize hyaluronan cable structures independent of inter-α-inhibitor heavy chain attachment Journal of Biological Chemistry. 284: 5313-5323. PMID 19075022 DOI: 10.1074/Jbc.M807979200  0.338
2009 Khatri S, Holguin F, Ryan PB, Mannino D, Erzurum S, Teague WG. Association of Ambient Ozone Exposure with Airway Inflammation and Allergy in Adults with Asthma Journal of Asthma. 46: 777-785. DOI: 10.3109/02770900902779284  0.421
2008 Masri FA, Comhair SA, Dostanic-Larson I, Kaneko FT, Dweik RA, Arroliga AC, Erzurum SC. Deficiency of lung antioxidants in idiopathic pulmonary arterial hypertension. Clinical and Translational Science. 1: 99-106. PMID 20443830 DOI: 10.1111/j.1752-8062.2008.00035.x  0.727
2008 Aytekin M, Comhair SA, de la Motte C, Bandyopadhyay SK, Farver CF, Hascall VC, Erzurum SC, Dweik RA. High levels of hyaluronan in idiopathic pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L789-99. PMID 18776053 DOI: 10.1152/Ajplung.90306.2008  0.346
2008 Lauer ME, Erzurum SC, Mukhopadhyay D, Vasanji A, Drazba J, Wang A, Fulop C, Hascall VC. Differentiated murine airway epithelial cells synthesize a leukocyte-adhesive hyaluronan matrix in response to endoplasmic reticulum stress. The Journal of Biological Chemistry. 283: 26283-96. PMID 18644783 DOI: 10.1074/Jbc.M803350200  0.345
2008 Lara A, Khatri SB, Wang Z, Comhair SA, Xu W, Dweik RA, Bodine M, Levison BS, Hammel J, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, ... ... Erzurum SC, et al. Alterations of the arginine metabolome in asthma. American Journal of Respiratory and Critical Care Medicine. 178: 673-81. PMID 18635886 DOI: 10.1164/Rccm.200710-1542Oc  0.351
2008 Planagumà A, Kazani S, Marigowda G, Haworth O, Mariani TJ, Israel E, Bleecker ER, Curran-Everett D, Erzurum SC, Calhoun WJ, Castro M, Chung KF, Gaston B, Jarjour NN, Busse WW, et al. Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma. American Journal of Respiratory and Critical Care Medicine. 178: 574-82. PMID 18583575 DOI: 10.1164/Rccm.200801-061Oc  0.385
2008 Asosingh K, Aldred MA, Vasanji A, Drazba J, Sharp J, Farver C, Comhair SA, Xu W, Licina L, Huang L, Anand-Apte B, Yoder MC, Tuder RM, Erzurum SC. Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. The American Journal of Pathology. 172: 615-27. PMID 18258847 DOI: 10.2353/Ajpath.2008.070705  0.357
2008 Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Erzurum SC, Gaston BM, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Wenzel SE, et al. Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. Journal of Applied Physiology (Bethesda, Md. : 1985). 104: 394-403. PMID 17991792 DOI: 10.1152/Japplphysiol.00329.2007  0.442
2007 Cannady SB, Batra PS, Leahy R, Citardi MJ, Janocha A, Ricci K, Comhair SAA, Bodine M, Wang Z, Hazen SL, Erzurum SC. Signal transduction and oxidative processes in sinonasal polyposis Journal of Allergy and Clinical Immunology. 120: 1346-1353. PMID 17935768 DOI: 10.1016/J.Jaci.2007.07.067  0.371
2007 Farha S, Asosingh K, Laskowski D, Licina L, Sekiguchi H, Sekigushi H, Losordo DW, Dweik RA, Wiedemann HP, Erzurum SC. Pulmonary gas transfer related to markers of angiogenesis during the menstrual cycle. Journal of Applied Physiology (Bethesda, Md. : 1985). 103: 1789-95. PMID 17717117 DOI: 10.1152/Japplphysiol.00614.2007  0.355
2007 Masri FA, Xu W, Comhair SA, Asosingh K, Koo M, Vasanji A, Drazba J, Anand-Apte B, Erzurum SC. Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L548-54. PMID 17526595 DOI: 10.1152/Ajplung.00428.2006  0.743
2007 Asosingh K, Swaidani S, Aronica M, Erzurum SC. Th1- and Th2-dependent endothelial progenitor cell recruitment and angiogenic switch in asthma Journal of Immunology. 178: 6482-6494. PMID 17475878 DOI: 10.4049/Jimmunol.178.10.6482  0.452
2007 Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. The Journal of Allergy and Clinical Immunology. 119: 405-13. PMID 17291857 DOI: 10.1016/J.Jaci.2006.11.639  0.422
2007 Xu W, Koeck T, Lara AR, Neumann D, DiFilippo FP, Koo M, Janocha AJ, Masri FA, Arroliga AC, Jennings C, Dweik RA, Tuder RM, Stuehr DJ, Erzurum SC. Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 1342-7. PMID 17227868 DOI: 10.1073/Pnas.0605080104  0.744
2007 Wenzel SE, Balzar S, Ampleford E, Hawkins GA, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum S, Gaston B, Israel E, Teague WG, Curran-Everett D, Meyers DA, Bleecker ER. IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression. American Journal of Respiratory and Critical Care Medicine. 175: 570-6. PMID 17170387 DOI: 10.1164/Rccm.200607-909Oc  0.399
2007 Xu W, Erzurum SC. Airways inflammation and reactive oxygen/nitrogen species in pulmonary hypertension Oxidative Stress: Clinical and Biomedical Implications. 259-276.  0.305
2006 Fitzpatrick AM, Gaston BM, Erzurum SC, Teague WG. Features of severe asthma in school-age children: Atopy and increased exhaled nitric oxide. The Journal of Allergy and Clinical Immunology. 118: 1218-25. PMID 17157650 DOI: 10.1016/J.Jaci.2006.08.019  0.367
2006 Gaston B, Kelly R, Urban P, Liu L, Henderson EM, Doctor A, Teague WG, Fitzpatrick A, Erzurum S, Hunt JF. Buffering airway acid decreases exhaled nitric oxide in asthma. The Journal of Allergy and Clinical Immunology. 118: 817-22. PMID 17030232 DOI: 10.1016/J.Jaci.2006.06.040  0.384
2006 Xu W, Zheng S, Goggans TM, Kiser P, Quinones-Mateu ME, Janocha AJ, Comhair SA, Slee R, Williams BR, Erzurum SC. Cystic fibrosis and normal human airway epithelial cell response to influenza a viral infection. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 609-27. PMID 16978065 DOI: 10.1089/Jir.2006.26.609  0.534
2006 Xu W, Zheng S, Dweik RA, Erzurum SC. Role of epithelial nitric oxide in airway viral infection. Free Radical Biology & Medicine. 41: 19-28. PMID 16781449 DOI: 10.1016/J.Freeradbiomed.2006.01.037  0.582
2006 Chambellan A, Cruickshank PJ, McKenzie P, Cannady SB, Szabo K, Comhair SA, Erzurum SC. Gene expression profile of human airway epithelium induced by hyperoxia in vivo. American Journal of Respiratory Cell and Molecular Biology. 35: 424-35. PMID 16690988 DOI: 10.1165/Rcmb.2005-0251Oc  0.363
2006 Ghosh S, Janocha AJ, Aronica MA, Swaidani S, Comhair SA, Xu W, Zheng L, Kaveti S, Kinter M, Hazen SL, Erzurum SC. Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation. Journal of Immunology (Baltimore, Md. : 1950). 176: 5587-97. PMID 16622028 DOI: 10.4049/Jimmunol.176.9.5587  0.434
2006 MUKHOPADHYAY D, LAUER M, DELAMOTTE C, ERZURUM S, FULOP C, HASCALL V. Can hyaluronan be the key player in lower airway inflammation? Matrix Biology. 25: S94-S94. DOI: 10.1016/J.Matbio.2006.08.257  0.386
2005 Masri FA, Anand-Apte B, Vasanji A, Xu W, Goggans T, Drazba J, Erzurum SC. Definitive evidence of fundamental and inherent alteration in the phenotype of primary pulmonary hypertension endothelial cells in angiogenesis. Chest. 128: 571S. PMID 16373830 DOI: 10.1378/Chest.128.6_Suppl.571S  0.72
2005 Hsieh FH, Sharma P, Gibbons A, Goggans T, Erzurum SC, Haque SJ. Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 14380-5. PMID 16186496 DOI: 10.1073/Pnas.0503948102  0.369
2005 Masini E, Bani D, Vannacci A, Pierpaoli S, Mannaioni PF, Comhair SA, Xu W, Muscoli C, Erzurum SC, Salvemini D. Reduction of antigen-induced respiratory abnormalities and airway inflammation in sensitized guinea pigs by a superoxide dismutase mimetic. Free Radical Biology & Medicine. 39: 520-31. PMID 16043023 DOI: 10.1016/J.Freeradbiomed.2005.04.006  0.45
2005 Lara AR, Erzurum SC. A urinary test for pulmonary arterial hypertension? American Journal of Respiratory and Critical Care Medicine. 172: 262-263. PMID 16040788 DOI: 10.1164/Rccm.2505009  0.323
2005 Hoit BD, Dalton ND, Erzurum SC, Laskowski D, Strohl KP, Beall CM. Nitric oxide and cardiopulmonary hemodynamics in Tibetan highlanders. Journal of Applied Physiology (Bethesda, Md. : 1985). 99: 1796-801. PMID 16024527 DOI: 10.1152/Japplphysiol.00205.2005  0.36
2005 Panda K, Chawla-Sarkar M, Santos C, Koeck T, Erzurum SC, Parkinson JF, Stuehr DJ. Visualizing inducible nitric-oxide synthase in living cells with a heme-binding fluorescent inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 102: 10117-22. PMID 16006534 DOI: 10.1073/Pnas.0408972102  0.325
2005 Masri FA, Comhair SA, Koeck T, Xu W, Janocha A, Ghosh S, Dweik RA, Golish J, Kinter M, Stuehr DJ, Erzurum SC, Aulak KS. Abnormalities in nitric oxide and its derivatives in lung cancer. American Journal of Respiratory and Critical Care Medicine. 172: 597-605. PMID 15947282 DOI: 10.1164/Rccm.200411-1523Oc  0.717
2005 Comhair SA, Ricci KS, Arroliga M, Lara AR, Dweik RA, Song W, Hazen SL, Bleecker ER, Busse WW, Chung KF, Gaston B, Hastie A, Hew M, Jarjour N, Moore W, ... ... Erzurum SC, et al. Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma. American Journal of Respiratory and Critical Care Medicine. 172: 306-13. PMID 15883124 DOI: 10.1164/Rccm.200502-180Oc  0.398
2005 Machado RF, Laskowski D, Deffenderfer O, Burch T, Zheng S, Mazzone PJ, Mekhail T, Jennings C, Stoller JK, Pyle J, Duncan J, Dweik RA, Erzurum SC. Detection of lung cancer by sensor array analyses of exhaled breath. American Journal of Respiratory and Critical Care Medicine. 171: 1286-91. PMID 15750044 DOI: 10.1164/Rccm.200409-1184Oc  0.515
2005 Comhair SA, Xu W, Ghosh S, Thunnissen FB, Almasan A, Calhoun WJ, Janocha AJ, Zheng L, Hazen SL, Erzurum SC. Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity. The American Journal of Pathology. 166: 663-74. PMID 15743779 DOI: 10.1016/S0002-9440(10)62288-2  0.438
2005 Comhair SAA, Erzurum SC. The regulation and role of extracellular glutathione peroxidase Antioxidants and Redox Signaling. 7: 72-79. PMID 15650397 DOI: 10.1089/Ars.2005.7.72  0.341
2004 Xu W, Kaneko FT, Zheng S, Comhair SA, Janocha AJ, Goggans T, Thunnissen FB, Farver C, Hazen SL, Jennings C, Dweik RA, Arroliga AC, Erzurum SC. Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1746-8. PMID 15364894 DOI: 10.1096/Fj.04-2317Fje  0.613
2004 Machado RF, Londhe Nerkar MV, Dweik RA, Hammel J, Janocha A, Pyle J, Laskowski D, Jennings C, Arroliga AC, Erzurum SC. Nitric oxide and pulmonary arterial pressures in pulmonary hypertension Free Radical Biology and Medicine. 37: 1010-1017. PMID 15336317 DOI: 10.1016/J.Freeradbiomed.2004.06.039  0.39
2004 Zheng S, Xu W, Bose S, Banerjee AK, Haque SJ, Erzurum SC. Impaired nitric oxide synthase-2 signaling pathway in cystic fibrosis airway epithelium. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L374-81. PMID 15107292 DOI: 10.1152/Ajplung.00039.2004  0.555
2003 Andreadis AA, Hazen SL, Comhair SAA, Erzurum SC. Oxidative and nitrosative events in asthma Free Radical Biology and Medicine. 35: 213-225. PMID 12885584 DOI: 10.1016/S0891-5849(03)00278-8  0.436
2003 Xu W, Comhair SA, Zheng S, Chu SC, Marks-Konczalik J, Moss J, Haque SJ, Erzurum SC. STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L137-48. PMID 12788789 DOI: 10.1152/Ajplung.00441.2002  0.508
2003 Zheng S, De BP, Choudhary S, Comhair SA, Goggans T, Slee R, Williams BR, Pilewski J, Haque SJ, Erzurum SC. Impaired innate host defense causes susceptibility to respiratory virus infections in cystic fibrosis. Immunity. 18: 619-30. PMID 12753739 DOI: 10.1016/S1074-7613(03)00114-6  0.519
2003 Khatri SB, Hammel J, Kavuru MS, Erzurum SC, Dweik RA. Temporal association of nitric oxide levels and airflow in asthma after whole lung allergen challenge Journal of Applied Physiology. 95: 436-440. PMID 12576414 DOI: 10.1152/Japplphysiol.01127.2002  0.406
2002 Machado RF, Stoller JK, Laskowski D, Zheng S, Lupica JA, Dweik RA, Erzurum SC. Low levels of nitric oxide and carbon monoxide in alpha 1-antitrypsin deficiency. Journal of Applied Physiology (Bethesda, Md. : 1985). 93: 2038-43. PMID 12391056 DOI: 10.1152/Japplphysiol.00659.2002  0.553
2002 Comhair SAA, Erzurum SC. Antioxidant responses to oxidant-mediated lung diseases American Journal of Physiology - Lung Cellular and Molecular Physiology. 283. PMID 12114185 DOI: 10.1152/Ajplung.00491.2001  0.344
2001 Özkan M, Dweik RA, Laskowski D, Arroliga AC, Erzurum SC. High levels of nitric oxide in individuals with pulmonary hypertension receiving epoprostenol therapy Lung. 179: 233-243. PMID 11891614 DOI: 10.1007/S004080000064  0.39
2001 Khatri SB, Özkan M, Mccarthy K, Laskowski D, Hammel J, Dweik RA, Erzurum SC. Alterations in exhaled gas profile during allergen-induced asthmatic response American Journal of Respiratory and Critical Care Medicine. 164: 1844-1848. PMID 11734434 DOI: 10.1164/Ajrccm.164.10.2106119  0.428
2001 Chung-man Ho J, Zheng S, Comhair SA, Farver C, Erzurum SC. Differential expression of manganese superoxide dismutase and catalase in lung cancer. Cancer Research. 61: 8578-85. PMID 11731445  0.52
2001 Beall CM, Laskowski D, Strohl KP, Soria R, Villena M, Vargas E, Alarcon AM, Gonzales C, Erzurum SC. Pulmonary nitric oxide in mountain dwellers Nature. 414: 411-412. PMID 11719794 DOI: 10.1038/35106641  0.368
2001 Eissa NT, Erzurum SC. Flexible bronchoscopy in molecular biology Clinics in Chest Medicine. 22: 343-353. PMID 11444117 DOI: 10.1016/S0272-5231(05)70048-4  0.342
2001 Uetani K, Arroliga ME, Erzurum SC. Double-stranded RNA dependence of nitric oxide synthase 2 expression in human bronchial epithelial cell lines BET-1A and BEAS-2B American Journal of Respiratory Cell and Molecular Biology. 24: 720-726. PMID 11415937 DOI: 10.1165/Ajrcmb.24.6.4297  0.338
2001 Uetani K, Thomassen MJ, Erzurum SC. Nitric oxide synthase 2 through an autocrine loop via respiratory epithelial cell-derived mediator American Journal of Physiology - Lung Cellular and Molecular Physiology. 280. PMID 11350796 DOI: 10.1152/Ajplung.2001.280.6.L1179  0.378
2001 MacPherson JC, Comhair SA, Erzurum SC, Klein DF, Lipscomb MF, Kavuru MS, Samoszuk MK, Hazen SL. Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species. Journal of Immunology (Baltimore, Md. : 1950). 166: 5763-72. PMID 11313420 DOI: 10.4049/Jimmunol.166.9.5763  0.408
2001 Dweik RA, Laskowski D, Özkan M, Farver C, Erzurum SC. High levels of exhaled nitric oxide (NO) and NO synthase III expression in lesional smooth muscle in lymphangioleiomyomatosis American Journal of Respiratory Cell and Molecular Biology. 24: 414-418. PMID 11306434 DOI: 10.1165/Ajrcmb.24.4.4127  0.352
2001 Dweik RA, Comhair SA, Gaston B, Thunnissen FB, Farver C, Thomassen MJ, Kavuru M, Hammel J, Abu-Soud HM, Erzurum SC. NO chemical events in the human airway during the immediate and late antigen-induced asthmatic response. Proceedings of the National Academy of Sciences of the United States of America. 98: 2622-7. PMID 11226289 DOI: 10.1073/Pnas.051629498  0.369
2001 Comhair SAA, Bhathena PR, Farver C, Thunnissen FBJM, Erzurum SC. Extracellular glutathione peroxidase induction in asthmatic lungs: Evidence for redox regulation of expression in human airway epithelial cells Faseb Journal. 15: 70-78. PMID 11149894 DOI: 10.1096/Fj.00-0085Com  0.427
2000 Comhair SAA, Thomassen MJ, Erzurum SC. Differential induction of extracellular glutathione peroxidase and nitric oxide synthase 2 in airways of healthy individuals exposed to 100% O2 or cigarette smoke American Journal of Respiratory Cell and Molecular Biology. 23: 350-354. PMID 10970826 DOI: 10.1165/Ajrcmb.23.3.4076  0.368
2000 Uetani K, Der SD, Zamanian-Daryoush M, De La Motte C, Lieberman BY, Williams BRG, Erzurum SC. Central role of double-stranded RNA-activated protein kinase in microbial induction of nitric oxide synthase Journal of Immunology. 165: 988-996. PMID 10878375 DOI: 10.4049/Jimmunol.165.2.988  0.322
2000 Bhathena PR, Comhair SAA, Holroyd KJ, Erzurum SC. Interleukin-9 receptor expression in asthmatic airways in vivo Lung. 178: 149-160. PMID 10871433 DOI: 10.1007/S004080000018  0.368
2000 Guo FH, Comhair SA, Zheng S, Dweik RA, Eissa NT, Thomassen MJ, Calhoun W, Erzurum SC. Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis. Journal of Immunology (Baltimore, Md. : 1950). 164: 5970-80. PMID 10820280 DOI: 10.4049/Jimmunol.164.11.5970  0.615
2000 Wu W, Samoszuk MK, Comhair SA, Thomassen MJ, Farver CF, Dweik RA, Kavuru MS, Erzurum SC, Hazen SL. Eosinophils generate brominating oxidants in allergen-induced asthma. The Journal of Clinical Investigation. 105: 1455-63. PMID 10811853 DOI: 10.1172/Jci9702  0.422
2000 Arroliga AC, Dweik RA, Kaneko FJT, Erzurum SC. Primary pulmonary hypertension: Update on pathogenesis and novel therapies Cleveland Clinic Journal of Medicine. 67: 175-190. PMID 10743306 DOI: 10.3949/Ccjm.67.3.175  0.322
2000 Comhair SAA, Bhathena PR, Dweik RA, Kavuru M, Erzurum SC. Rapid loss of superoxide dismutase activity during antigen-induced asthmatic response Lancet. 355: 624. PMID 10696986 DOI: 10.1016/S0140-6736(99)04736-4  0.424
1999 Thomassen MJ, Raychaudhuri B, Dweik RA, Farver C, Buhrow L, Malur A, Connors MJ, Drazba J, Hammel J, Erzurum SC, Kavuru MS. Nitric oxide regulation of asthmatic airway inflammation with segmental allergen challenge. The Journal of Allergy and Clinical Immunology. 104: 1174-82. PMID 10588998 DOI: 10.1016/S0091-6749(99)70010-2  0.399
1999 Raychaudhuri B, Dweik R, Connors MJ, Buhrow L, Malur A, Drazba J, Arroliga AC, Erzurum SC, Kavuru MS, Thomassen MJ. Nitric oxide blocks nuclear factor-kappaB activation in alveolar macrophages. American Journal of Respiratory Cell and Molecular Biology. 21: 311-6. PMID 10460748 DOI: 10.1165/Ajrcmb.21.3.3611  0.378
1999 Bhattacharyya N, Chen HC, Comhair S, Erzurum SC, Banerjee S. Variant forms of DNA polymerase β in primary lung carcinomas Dna and Cell Biology. 18: 549-554. PMID 10433553 DOI: 10.1089/104454999315097  0.317
1999 Comhair SA, Lewis MJ, Bhathena PR, Hammel JP, Erzurum SC. Increased glutathione and glutathione peroxidase in lungs of individuals with chronic beryllium disease. American Journal of Respiratory and Critical Care Medicine. 159: 1824-9. PMID 10351926 DOI: 10.1164/Ajrccm.159.6.9810044  0.35
1999 Khatri SB, Erzurum SC. Alternative therapies for corticosteroid-dependent asthma Clinical Pulmonary Medicine. 6: 271-277. DOI: 10.1097/00045413-199909000-00001  0.393
1998 Kaneko FT, Arroliga AC, Dweik RA, Comhair SA, Laskowski D, Oppedisano R, Thomassen MJ, Erzurum SC. Biochemical reaction products of nitric oxide as quantitative markers of primary pulmonary hypertension American Journal of Respiratory and Critical Care Medicine. 158: 917-923. PMID 9731026 DOI: 10.1164/Ajrccm.158.3.9802066  0.369
1998 Binion DG, Fu S, Ramanujam KS, Chai YC, Dweik RA, Drazba JA, Wade JG, Ziats NP, Erzurum SC, Wilson KT. iNOS expression in human intestinal microvascular endothelial cells inhibits leukocyte adhesion. The American Journal of Physiology. 275: G592-603. PMID 9724273 DOI: 10.1152/Ajpgi.1998.275.3.G592  0.343
1998 Dweik RA, Laskowski D, Abu-Soud HM, Kaneko FT, Hutte R, Stuehr DJ, Erzurum SC. Nitric oxide synthesis in the lung. Regulation by oxygen through a kinetic mechanism Journal of Clinical Investigation. 101: 660-666. PMID 9449700 DOI: 10.1172/Jci1378  0.332
1998 Dweik RA, Laskowski D, Erzurum SC. Kinetics of nitric oxide accumulation in the lower airways of asthmatics and controls Chest. 114.  0.302
1997 Dweik RA, Lewis M, Kavuru M, Buhrow L, Erzurum SC, Thomassen MJ. Inhaled corticosteroids and β-agonists inhibit oxidant production by bronchoalveolar lavage cells from normal volunteers in vivo Immunopharmacology. 37: 163-166. PMID 9403334 DOI: 10.1016/S0162-3109(97)00043-X  0.339
1997 Guo FH, Uetani K, Haque SJ, Williams BRG, Dweik RA, Thunnissen FBJM, Calhoun W, Erzurum SC. Interferon γ and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators Journal of Clinical Investigation. 100: 829-838. PMID 9259582 DOI: 10.1172/Jci119598  0.322
1997 De Raeve HR, Thunnissen FBJM, Kaneko FT, Guo FH, Lewis M, Kavuru MS, Secic M, Thomassen MJ, Erzurum SC. Decreased Cu,Zn-SOD activity in asthmatic airway epithelium: Correction by inhaled corticosteroid in vivo American Journal of Physiology - Lung Cellular and Molecular Physiology. 272. PMID 9038914 DOI: 10.1152/Ajplung.1997.272.1.L148  0.311
1996 Danel C, Erzurum SC, Mcelvaney NC, Crystal RC. Quantitative assessment of the epithelial and inflammatory cell populations in large airways of normals and individuals with cystic fibrosis American Journal of Respiratory and Critical Care Medicine. 153: 362-368. PMID 8542144 DOI: 10.1164/Ajrccm.153.1.8542144  0.353
1995 Kavuru MS, Pien L, Litwin D, Erzurum S, Ahmad M. Asthma: current controversies and emerging therapies. Cleveland Clinic Journal of Medicine. 62: 293-304. PMID 7586485 DOI: 10.3949/Ccjm.62.5.293  0.356
1995 Guo FH, De Raeve HR, Rice TW, Stuehr DJ, Thunnissen FBJM, Erzurum SC. Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo Proceedings of the National Academy of Sciences of the United States of America. 92: 7809-7813. PMID 7544004 DOI: 10.1073/Pnas.92.17.7809  0.456
1994 Yoo JH, Erzurum SC, Hay JG, Lemarchand P, Crystal RG. Vulnerability of the human airway epithelium to hyperoxia: Constitutive expression of the catalase gene in human bronchial epithelial cells despite oxidant stress Journal of Clinical Investigation. 93: 297-302. PMID 8282800 DOI: 10.1172/Jci116959  0.33
1993 Erzurum SC, Lemarchand P, Rosenfeld MA, Yoo JH, Crystal RG. Protection of human endothelial cells from oxidant injury by adenovirus-mediated transfer of the human catalase cDNA Nucleic Acids Research. 21: 1607-1612. PMID 8479912 DOI: 10.1093/Nar/21.7.1607  0.338
1993 Erzurum SC, Danel C, Gillissen A, Chu CS, Trapnell BC, Crystal RG. In vivo antioxidant gene expression in human airway epithelium of normal individuals exposed to 100% O2 Journal of Applied Physiology. 75: 1256-1262. PMID 8226538 DOI: 10.1152/Jappl.1993.75.3.1256  0.304
1991 Erzurum SC, Leff JA, Cochran JE, Ackerson LM, Szefler SJ, Martin RJ, Cott GR. Lack of benefit of methotrexate in severe, steroid-dependent asthma. A double-blind, placebo-controlled study. Annals of Internal Medicine. 114: 353-60. PMID 1992876 DOI: 10.7326/0003-4819-114-5-353  0.427
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