Daniel Flynn - Publications

Affiliations: 
West Virginia University, Morgantown, WV, United States 
Area:
Cell Biology, Molecular Biology, Microbiology Biology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Karagiannis GS, Sharma VP, Brizio S, Burt J, Wang Y, Entenberg D, Smith B, Flynn D, Oktay MH, Condeelis J. Abstract B030: Neoadjuvant chemotherapy promotes macrophage-induced MenaINV-dependent pro-metastatic changes in breast tumors Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B030  0.322
2017 Groot Jd, George S, Razak A, Gordon M, Janku F, Ligon K, Wen P, Friedlander S, Flynn D, Kaufman M, Pitman J, Ruiz-Soto R, Smith B, Westwood D, Rosen O, et al. ACTR-02. DCC-2618, A NOVEL pan-KIT AND PDGFRa KINASE SWITCH CONTROL INHIBITOR, SHOWS ENCOURAGING SIGNAL IN A PATIENT (PT) WITH GLIOBLASTOMA (GBM) Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.002  0.312
2015 Cunnick JM, Kim S, Hadsell J, Collins S, Cerra C, Reiser P, Flynn DC, Cho Y. Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland. Oncogene. 34: 2640-9. PMID 25043309 DOI: 10.1038/Onc.2014.205  0.395
2015 Leung E, Wang Y, Smith B, Flynn D, Condeelis J. Abstract 5091: Inhibiting endothelium directed tumor cell streaming by targeting the HGF/C-Met and EGF/CSF-1 signaling pathways Cancer Research. 75: 5091-5091. DOI: 10.1158/1538-7445.Am2015-5091  0.325
2015 Pignatelli J, Jones J, Chen X, Smith B, Flynn D, Condeelis J, Oktay M. Abstract 4112: Mechanisms of transendothelial migration by invasive breast carcinoma cells from patients Cancer Research. 75: 4112-4112. DOI: 10.1158/1538-7445.Am2015-4112  0.309
2014 Sims-Mourtada J, Opdenaker LM, Davis J, Arnold KM, Flynn D. Taxane-induced hedgehog signaling is linked to expansion of breast cancer stem-like populations after chemotherapy. Molecular Carcinogenesis. PMID 25263583 DOI: 10.1002/Mc.22225  0.302
2011 Snyder BN, Cho Y, Qian Y, Coad JE, Flynn DC, Cunnick JM. AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes. European Journal of Cell Biology. 90: 376-89. PMID 21333378 DOI: 10.1016/J.Ejcb.2010.11.016  0.764
2010 Clump DA, Yu JJ, Cho Y, Gao R, Jett J, Zot H, Cunnick JM, Snyder B, Clump AC, Dodrill M, Gannett P, Coad JE, Shurina R, Figg WD, Reed E, ... Flynn DC, et al. A Polymorphic Variant of AFAP-110 Enhances cSrc Activity. Translational Oncology. 3: 276-85. PMID 20689769 DOI: 10.1593/Tlo.10106  0.71
2009 Xu X, Harder J, Flynn DC, Lanier LM. AFAP120 regulates actin organization during neuronal differentiation. Differentiation; Research in Biological Diversity. 77: 38-47. PMID 19281763 DOI: 10.1016/j.diff.2008.09.006  0.399
2008 Dorfleutner A, Cho Y, Vincent D, Cunnick J, Lin H, Weed SA, Stehlik C, Flynn DC. Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells. Journal of Cell Science. 121: 2394-405. PMID 18577577 DOI: 10.1242/Jcs.026187  0.384
2007 Zhang J, Park SI, Artime MC, Summy JM, Shah AN, Bomser JA, Dorfleutner A, Flynn DC, Gallick GE. AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts. The Journal of Clinical Investigation. 117: 2962-73. PMID 17885682 DOI: 10.1172/Jci30710  0.711
2007 Walker VG, Ammer A, Cao Z, Clump AC, Jiang BH, Kelley LC, Weed SA, Zot H, Flynn DC. PI3K activation is required for PMA-directed activation of cSrc by AFAP-110. American Journal of Physiology. Cell Physiology. 293: C119-32. PMID 17360811 DOI: 10.1152/Ajpcell.00525.2006  0.752
2007 Dorfleutner A, Bryan NB, Talbott SJ, Funya KN, Rellick SL, Reed JC, Shi X, Rojanasakul Y, Flynn DC, Stehlik C. Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation. Infection and Immunity. 75: 1484-92. PMID 17178784 DOI: 10.1128/Iai.01315-06  0.346
2005 Clump DA, Qazi IH, Sudol M, Flynn DC. c-Yes response to growth factor activation. Growth Factors (Chur, Switzerland). 23: 263-72. PMID 16338789 DOI: 10.1080/08977190500199360  0.665
2005 Qian Y, Zhong X, Flynn DC, Zheng JZ, Qiao M, Wu C, Dedhar S, Shi X, Jiang BH. ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling. Oncogene. 24: 3154-65. PMID 15735674 DOI: 10.1038/Sj.Onc.1208525  0.417
2005 Qian Y, Liu KJ, Chen Y, Flynn DC, Castranova V, Shi X. Cdc42 regulates arsenic-induced NADPH oxidase activation and cell migration through actin filament reorganization. The Journal of Biological Chemistry. 280: 3875-84. PMID 15492012 DOI: 10.1074/jbc.M403788200  0.336
2004 Gatesman A, Walker VG, Baisden JM, Weed SA, Flynn DC. Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110. Molecular and Cellular Biology. 24: 7578-97. PMID 15314167 DOI: 10.1128/Mcb.24.17.7578-7597.2004  0.798
2004 Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. American Journal of Physiology. Cell Physiology. 287: C281-91. PMID 15028555 DOI: 10.1152/Ajpcell.00422.2003  0.711
2004 Qian Y, Gatesman AS, Baisden JM, Zot HG, Cherezova L, Qazi I, Mazloum N, Lee MY, Guappone-Koay A, Flynn DC. Analysis of the role of the leucine zipper motif in regulating the ability of AFAP-110 to alter actin filament integrity. Journal of Cellular Biochemistry. 91: 602-20. PMID 14755689 DOI: 10.1002/Jcb.10725  0.779
2004 Qian Y, Corum L, Meng Q, Blenis J, Zheng JZ, Shi X, Flynn DC, Jiang BH. PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration. American Journal of Physiology. Cell Physiology. 286: C153-63. PMID 12967912 DOI: 10.1152/Ajpcell.00142.2003  0.393
2003 Summy JM, Qian Y, Jiang BH, Guappone-Koay A, Gatesman A, Shi X, Flynn DC. The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src. Journal of Cell Science. 116: 2585-98. PMID 12734402 DOI: 10.1242/Jcs.00466  0.751
2003 Clump DA, Clem R, Qian Y, Guappone-Koay A, Berrebi AS, Flynn DC. Protein expression levels of the Src activating protein AFAP are developmentally regulated in brain. Journal of Neurobiology. 54: 473-85. PMID 12532398 DOI: 10.1002/Neu.10143  0.653
2003 Summy JM, Sudol M, Eck MJ, Monteiro AN, Gatesman A, Flynn DC. Specificity in signaling by c-Yes. Frontiers in Bioscience : a Journal and Virtual Library. 8: s185-205. PMID 12456296 DOI: 10.2741/1011  0.719
2002 Berwanger B, Hartmann O, Bergmann E, Bernard S, Nielsen D, Krause M, Kartal A, Flynn D, Wiedemeyer R, Schwab M, Schäfer H, Christiansen H, Eilers M. Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma. Cancer Cell. 2: 377-86. PMID 12450793 DOI: 10.1016/S1535-6108(02)00179-4  0.378
2002 Qian Y, Baisden JM, Cherezova L, Summy JM, Guappone-Koay A, Shi X, Mast T, Pustula J, Zot HG, Mazloum N, Lee MY, Flynn DC. PC phosphorylation increases the ability of AFAP-110 to cross-link actin filaments. Molecular Biology of the Cell. 13: 2311-22. PMID 12134071 DOI: 10.1091/Mbc.E01-12-0148  0.801
2002 Cherezova L, Gatesman A, Flynn DC. The effects of phosphorylation on adaptor protein function. Frontiers in Bioscience : a Journal and Virtual Library. 7: d164-203. PMID 11779691  0.318
2001 Baisden JM, Gatesman AS, Cherezova L, Jiang BH, Flynn DC. The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases. Oncogene. 20: 6607-16. PMID 11641786 DOI: 10.1038/Sj.Onc.1204802  0.806
2001 Baisden JM, Qian Y, Zot HM, Flynn DC. The actin filament-associated protein AFAP-110 is an adaptor protein that modulates changes in actin filament integrity. Oncogene. 20: 6435-47. PMID 11607843 DOI: 10.1038/Sj.Onc.1204784  0.804
2001 Hoey JG, Summy J, Flynn DC. Chimeric constructs containing the SH4/Unique domains of cYes can restrict the ability of Src(527F) to upregulate heme oxygenase-1 expression efficiently. Cellular Signalling. 12: 691-701. PMID 11080622 DOI: 10.1016/S0898-6568(00)00116-9  0.743
2001 Hoey JG, Summy J, Flynn DC. Erratum to “Chimeric construct containing the SH4/Unique domains of cYes can restrict the ability of Src527F to upregulate heme oxygenese-1 expression efficiently” [Cell. Signal. 12 (2000) 691–701] Cellular Signalling. 13: 71. DOI: 10.1016/S0898-6568(01)00128-0  0.723
2000 Qian Y, Baisden JM, Zot HG, Van Winkle WB, Flynn DC. The carboxy terminus of AFAP-110 modulates direct interactions with actin filaments and regulates its ability to alter actin filament integrity and induce lamellipodia formation. Experimental Cell Research. 255: 102-13. PMID 10666339 DOI: 10.1006/Excr.1999.4795  0.789
2000 Summy JM, Guappone AC, Sudol M, Flynn DC. The SH3 and SH2 domains are capable of directing specificity in protein interactions between the non-receptor tyrosine kinases cSrc and cYes. Oncogene. 19: 155-60. PMID 10644991 DOI: 10.1038/Sj.Onc.1203265  0.755
1999 Qian Y, Guappone AC, Baisden JM, Hill MW, Summy JM, Flynn DC. Monoclonal antibodies directed against AFAP-110 recognize species- specific and conserved epitopes Hybridoma. 18: 167-175. PMID 10380016  0.782
1998 Guappone AC, Weimer T, Flynn DC. Formation of a stable src-AFAP-110 complex through either an amino-terminal or a carboxy-terminal SH2-binding motif. Molecular Carcinogenesis. 22: 110-9. PMID 9655255 DOI: 10.1002/(SICI)1098-2744(199806)22:2<110::AID-MC6>3.0.CO;2-Q  0.389
1998 Qian Y, Baisden JM, Westin EH, Guappone AC, Koay TC, Flynn DC. Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and actin filament integrity. Oncogene. 16: 2185-95. PMID 9619827 DOI: 10.1038/Sj.Onc.1201753  0.779
1997 Guappone AC, Flynn DC. The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src. Molecular and Cellular Biochemistry. 175: 243-52. PMID 9350057 DOI: 10.1023/A:1006840104666  0.388
1993 Schaller MD, Bouton AH, Flynn DC, Parsons JT. Identification and characterization of novel substrates for protein tyrosine kinases Progress in Nucleic Acid Research and Molecular Biology. 44: 205-227. PMID 8434124 DOI: 10.1016/S0079-6603(08)60221-4  0.334
1993 Flynn DC, Leu TH, Reynolds AB, Parsons JT. Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate. Molecular and Cellular Biology. 13: 7892-900. PMID 8247004 DOI: 10.1128/mcb.13.12.7892-7900.1993  0.422
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