Carolina B. Lopez, Ph.D. - Publications

Affiliations: 
2002 Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Immunology, Microbiology Biology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Castro ÍA, Yang Y, Gnazzo V, Kim DH, Van Dyken SJ, López CB. Murine Parainfluenza Virus Persists in Lung Innate Immune Cells Sustaining Chronic Lung Pathology. Biorxiv : the Preprint Server For Biology. PMID 37986974 DOI: 10.1101/2023.11.07.566103  0.532
2023 González Aparicio LJ, Yang Y, Hackbart M, López CB. Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity. Plos Biology. 21: e3002381. PMID 37983241 DOI: 10.1371/journal.pbio.3002381  0.569
2023 Hackbart M, López CB. S RNA Intergenic Deletions Drive Viral Interference during Arenavirus Infections. Biorxiv : the Preprint Server For Biology. PMID 37961573 DOI: 10.1101/2023.10.31.564889  0.401
2023 Achouri E, Felt SA, Hackbart M, Rivera-Espinal NS, López CB. VODKA2: a fast and accurate method to detect non-standard viral genomes from large RNA-seq data sets. Rna (New York, N.Y.). 30: 16-25. PMID 37891004 DOI: 10.1261/rna.079747.123  0.361
2023 Aparicio LJG, Yang Y, Hackbart MS, Manzoni TB, López CB. Copyback viral genomes trigger stress granule formation independent of the antiviral response to interfere with viral translation in acute and persistent infections. Biorxiv : the Preprint Server For Biology. PMID 37292625 DOI: 10.1101/2023.05.17.541157  0.571
2023 Achouri E, Felt SA, Hackbart M, López CB. VODKA2: An accurate method to detect copy-back and deletion viral genomes from next-generation sequencing data. Biorxiv : the Preprint Server For Biology. PMID 37163001 DOI: 10.1101/2023.04.25.537842  0.331
2023 Cable J, Sun J, Cheon IS, Vaughan AE, Castro IA, Stein SR, López CB, Gostic KM, Openshaw PJM, Ellebedy AH, Wack A, Hutchinson E, Thomas MM, Langlois RA, Lingwood D, et al. Respiratory viruses: New frontiers-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 36722473 DOI: 10.1111/nyas.14958  0.402
2022 Fisher DG, Gnazzo V, Holthausen DJ, López CB. Non-standard viral genome-derived RNA activates TLR3 and type I IFN signaling to induce cDC1-dependent CD8+ T-cell responses during vaccination in mice. Vaccine. 40: 7270-7279. PMID 36333225 DOI: 10.1016/j.vaccine.2022.10.052  0.383
2022 Felt SA, Achouri E, Faber SR, López CB. Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back viral genome population followed by selection. Virus Evolution. 8: veac091. PMID 36325033 DOI: 10.1093/ve/veac091  0.539
2022 Hiller BE, Yin Y, Perng YC, de Araujo Castro Í, Fox LE, Locke MC, Monte KJ, López CB, Ornitz DM, Lenschow DJ. Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis. Plos Pathogens. 18: e1010228. PMID 35675358 DOI: 10.1371/journal.ppat.1010228  0.533
2022 González Aparicio LJ, López CB, Felt SA. A Virus Is a Community: Diversity within Negative-Sense RNA Virus Populations. Microbiology and Molecular Biology Reviews : Mmbr. e0008621. PMID 35658541 DOI: 10.1128/mmbr.00086-21  0.386
2022 Felt SA, López CB. Harnessing defective viruses to fight infections. Med (New York, N.Y.). 3: 1-2. PMID 35590140 DOI: 10.1016/j.medj.2021.12.006  0.448
2021 Felt SA, Sun Y, Jozwik A, Paras A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster KA, Cárdenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, et al. Detection of respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes. Nature Microbiology. PMID 33795879 DOI: 10.1038/s41564-021-00882-3  0.458
2020 Genoyer E, Kulej K, Hung CT, Thibault PA, Azarm K, Takimoto T, Garcia BA, Lee B, Lakdawala S, Weitzman MD, López CB. The Viral Polymerase Complex Mediates the Interaction of Viral Ribonucleoprotein Complexes with Recycling Endosomes during Sendai Virus Assembly. Mbio. 11. PMID 32843550 DOI: 10.1128/Mbio.02028-20  0.582
2020 Zhang T, Yin C, Boyd DF, Quarato G, Ingram JP, Shubina M, Ragan KB, Ishizuka T, Crawford JC, Tummers B, Rodriguez DA, Xue J, Peri S, Kaiser WJ, López CB, et al. Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis. Cell. 180: 1115-1129.e13. PMID 32200799 DOI: 10.1016/J.Cell.2020.02.050  0.524
2019 Garcia GL, Valenzuela A, Manzoni T, Vaughan A, López CB. Distinct chronic post-viral lung diseases upon infection with influenza or parainfluenza viruses differentially impact superinfection outcome. The American Journal of Pathology. PMID 31866346 DOI: 10.1016/J.Ajpath.2019.11.003  0.539
2019 Sun Y, Kim EJ, Felt SA, Taylor LJ, Agarwal D, Grant GR, López CB. Correction: A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes. Plos Pathogens. 15: e1008099. PMID 31581268 DOI: 10.1371/Journal.Ppat.1008099  0.399
2019 Sengupta S, Tang SY, Devine JC, Anderson ST, Nayak S, Zhang SL, Valenzuela A, Fisher DG, Grant GR, López CB, FitzGerald GA. Circadian control of lung inflammation in influenza infection. Nature Communications. 10: 4107. PMID 31511530 DOI: 10.1038/S41467-019-11400-9  0.527
2019 Vignuzzi M, López CB. Defective viral genomes are key drivers of the virus-host interaction. Nature Microbiology. PMID 31160826 DOI: 10.1038/S41564-019-0465-Y  0.546
2019 Genoyer E, López CB. The Impact of Defective Viruses on Infection and Immunity. Annual Review of Virology. PMID 31082310 DOI: 10.1146/Annurev-Virology-092818-015652  0.618
2019 Sun Y, Kim EJ, Felt SA, Taylor LJ, Agarwal D, Grant GR, López CB. A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes. Plos Pathogens. 15: e1007707. PMID 30995283 DOI: 10.1371/journal.ppat.1007707  0.426
2019 López CB. Unexpected lessons from the neglected: How defective viral genomes became important again. Plos Pathogens. 15: e1007450. PMID 30629697 DOI: 10.1371/Journal.Ppat.1007450  0.357
2018 Genoyer E, López CB. Defective viral genomes alter how Sendai virus interacts with cellular trafficking machinery leading to heterogeneity in the production of viral particles among infected cells. Journal of Virology. PMID 30463965 DOI: 10.1128/Jvi.01579-18  0.594
2018 Manzoni TB, López CB. Defective (interfering) viral genomes re-explored: impact on antiviral immunity and virus persistence. Future Virology. 13: 493-503. PMID 30245734 DOI: 10.2217/Fvl-2018-0021  0.575
2018 Fisher DG, Coppock GM, López CB. Virus-derived immunostimulatory RNA induces type I IFN-dependent antibodies and T-cell responses during vaccination. Vaccine. PMID 29861183 DOI: 10.1016/J.Vaccine.2018.05.100  0.548
2017 Xu J, Sun Y, Li Y, Ruthel G, Weiss SR, Raj A, Beiting D, López CB. Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence. Nature Communications. 8: 799. PMID 28986577 DOI: 10.1038/S41467-017-00909-6  0.631
2017 Kenney AD, Dowdle JA, Bozzacco L, McMichael TM, St Gelais C, Panfil AR, Sun Y, Schlesinger LS, Anderson MZ, Green PL, López CB, Rosenberg BR, Wu L, Yount JS. Human Genetic Determinants of Viral Diseases. Annual Review of Genetics. PMID 28853921 DOI: 10.1146/Annurev-Genet-120116-023425  0.804
2017 Muallem G, Wagage S, Sun Y, DeLong JH, Valenzuela A, Christian DA, Harms Pritchard G, Fang Q, Buza EL, Jain D, Elloso MM, López CB, Hunter CA. IL-27 LIMITS TYPE 2 IMMUNOPATHOLOGY FOLLOWING PARAINFLUENZA VIRUS INFECTION. Plos Pathogens. 13: e1006173. PMID 28129374 DOI: 10.1371/Journal.Ppat.1006173  0.425
2016 Sun Y, López CB. Respiratory Syncytial Virus Infection in Mice and Detection of Viral Genomes in the Lung Using RT-qPCR. Bio-Protocol. 6. PMID 30112423 DOI: 10.21769/BioProtoc.1819  0.441
2016 Sun Y, López CB. Preparation of Respiratory Syncytial Virus with High or Low Content of Defective Viral Particles and Their Purification from Viral Stocks. Bio-Protocol. 6. PMID 30079370 DOI: 10.21769/BioProtoc.1820  0.5
2016 Philip NH, DeLaney A, Peterson LW, Santos-Marrero M, Grier JT, Sun Y, Wynosky-Dolfi MA, Zwack EE, Hu B, Olsen TM, Rongvaux A, Pope SD, López CB, Oberst A, Beiting DP, et al. Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death. Plos Pathogens. 12: e1005910. PMID 27737018 DOI: 10.1371/Journal.Ppat.1005910  0.462
2016 Sun Y, López CB. The innate immune response to RSV: Advances in our understanding of critical viral and host factors. Vaccine. PMID 27686836 DOI: 10.1016/J.Vaccine.2016.09.030  0.638
2016 Nogusa S, Thapa RJ, Dillon CP, Liedmann S, Oguin TH, Ingram JP, Rodriguez DA, Kosoff R, Sharma S, Sturm O, Verbist K, Gough PJ, Bertin J, Hartmann BM, Sealfon SC, et al. RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus. Cell Host & Microbe. PMID 27321907 DOI: 10.1016/J.Chom.2016.05.011  0.601
2016 Penkala I, Wang J, Syrett CM, Goetzl L, López CB, Anguera MC. LNCRHOXF1: a long noncoding RNA from the X-chromosome that suppresses viral response genes during development of the early human placenta. Molecular and Cellular Biology. PMID 27066803 DOI: 10.1128/Mcb.01098-15  0.461
2016 Xue J, Chambers BS, Hensley SE, López CB. Propagation and Characterization of Influenza Virus Stocks That Lack High Levels of Defective Viral Genomes and Hemagglutinin Mutations. Frontiers in Microbiology. 7: 326. PMID 27047455 DOI: 10.3389/Fmicb.2016.00326  0.535
2015 Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M, Raj A, López CB. Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I. Mbio. 6. PMID 26443454 DOI: 10.1128/Mbio.01265-15  0.652
2015 Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA, Hodinka RL, López CB. Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans. Plos Pathogens. 11: e1005122. PMID 26336095 DOI: 10.1371/Journal.Ppat.1005122  0.614
2015 Benitez AA, Panis M, Xue J, Varble A, Shim JV, Frick AL, López CB, Sachs D, tenOever BR. In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus. Cell Reports. 11: 1714-26. PMID 26074083 DOI: 10.1016/J.Celrep.2015.05.032  0.585
2014 López CB. Defective viral genomes: critical danger signals of viral infections. Journal of Virology. 88: 8720-3. PMID 24872580 DOI: 10.1128/Jvi.00707-14  0.582
2014 Kim WK, Jain D, Sánchez MD, Koziol-White CJ, Matthews K, Ge MQ, Haczku A, Panettieri RA, Frieman MB, López CB. Deficiency of melanoma differentiation-associated protein 5 results in exacerbated chronic postviral lung inflammation. American Journal of Respiratory and Critical Care Medicine. 189: 437-48. PMID 24417465 DOI: 10.1164/Rccm.201307-1338Oc  0.631
2013 Tapia K, Kim WK, Sun Y, Mercado-López X, Dunay E, Wise M, Adu M, López CB. Defective viral genomes arising in vivo provide critical danger signals for the triggering of lung antiviral immunity. Plos Pathogens. 9: e1003703. PMID 24204261 DOI: 10.1371/Journal.Ppat.1003703  0.76
2013 Mercado-López X, Cotter CR, Kim WK, Sun Y, Muñoz L, Tapia K, López CB. Highly immunostimulatory RNA derived from a Sendai virus defective viral genome. Vaccine. 31: 5713-21. PMID 24099876 DOI: 10.1016/J.Vaccine.2013.09.040  0.778
2012 Hermesh T, Moran TM, Jain D, López CB. Granulocyte colony-stimulating factor protects mice during respiratory virus infections. Plos One. 7: e37334. PMID 22615983 DOI: 10.1371/Journal.Pone.0037334  0.828
2011 Harty RN, Schmitt AP, Bouamr F, Lopez CB, Krummenacher C. Virus budding/host interactions. Advances in Virology. 2011: 963192. PMID 22312359 DOI: 10.1155/2011/963192  0.566
2011 Cotter CR, Kim WK, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM. The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling. Journal of Virology. 85: 12662-72. PMID 21937652 DOI: 10.1128/Jvi.05557-11  0.839
2011 López CB, Hermesh T. Systemic responses during local viral infections: type I IFNs sound the alarm. Current Opinion in Immunology. 23: 495-9. PMID 21752617 DOI: 10.1016/J.Coi.2011.06.003  0.838
2011 Hu J, Nudelman G, Shimoni Y, Kumar M, Ding Y, López C, Hayot F, Wetmur JG, Sealfon SC. Role of cell-to-cell variability in activating a positive feedback antiviral response in human dendritic cells. Plos One. 6: e16614. PMID 21347441 DOI: 10.1371/Journal.Pone.0016614  0.5
2010 Hermesh T, Moltedo B, López CB, Moran TM. Buying time-the immune system determinants of the incubation period to respiratory viruses. Viruses. 2: 2541-58. PMID 21994630 DOI: 10.3390/V2112541  0.808
2010 Yount JS, Moltedo B, Yang YY, Charron G, Moran TM, López CB, Hang HC. Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3. Nature Chemical Biology. 6: 610-4. PMID 20601941 DOI: 10.1038/Nchembio.405  0.798
2010 Hermesh T, Moltedo B, Moran TM, López CB. Antiviral instruction of bone marrow leukocytes during respiratory viral infections. Cell Host & Microbe. 7: 343-53. PMID 20478536 DOI: 10.1016/J.Chom.2010.04.006  0.797
2010 Cotter CR, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM. The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells. Plos One. 5: e8684. PMID 20174621 DOI: 10.1371/Journal.Pone.0008684  0.856
2009 Moltedo B, López CB, Pazos M, Becker MI, Hermesh T, Moran TM. Cutting edge: stealth influenza virus replication precedes the initiation of adaptive immunity. Journal of Immunology (Baltimore, Md. : 1950). 183: 3569-73. PMID 19717515 DOI: 10.4049/Jimmunol.0900091  0.82
2008 Escribese MM, Kraus T, Rhee E, Fernandez-Sesma A, López CB, Moran TM. Estrogen inhibits dendritic cell maturation to RNA viruses. Blood. 112: 4574-84. PMID 18802009 DOI: 10.1182/Blood-2008-04-148692  0.776
2008 Yount JS, Gitlin L, Moran TM, López CB. MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai Virus defective interfering particles. Journal of Immunology (Baltimore, Md. : 1950). 180: 4910-8. PMID 18354215 DOI: 10.4049/Jimmunol.180.7.4910  0.821
2007 Yount JS, Moran TM, López CB. Cytokine-independent upregulation of MDA5 in viral infection. Journal of Virology. 81: 7316-9. PMID 17475649 DOI: 10.1128/Jvi.00545-07  0.854
2006 Yount JS, Kraus TA, Horvath CM, Moran TM, López CB. A novel role for viral-defective interfering particles in enhancing dendritic cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 177: 4503-13. PMID 16982887 DOI: 10.4049/Jimmunol.177.7.4503  0.832
2006 López CB, Yount JS, Hermesh T, Moran TM. Sendai virus infection induces efficient adaptive immunity independently of type I interferons. Journal of Virology. 80: 4538-45. PMID 16611914 DOI: 10.1128/Jvi.80.9.4538-4545.2006  0.822
2006 López CB, Yount JS, Moran TM. Toll-like receptor-independent triggering of dendritic cell maturation by viruses. Journal of Virology. 80: 3128-34. PMID 16537581 DOI: 10.1128/Jvi.80.7.3128-3134.2006  0.847
2004 López CB, Moltedo B, Alexopoulou L, Bonifaz L, Flavell RA, Moran TM. TLR-independent induction of dendritic cell maturation and adaptive immunity by negative-strand RNA viruses. Journal of Immunology (Baltimore, Md. : 1950). 173: 6882-9. PMID 15557183 DOI: 10.4049/Jimmunol.173.11.6882  0.857
2003 López CB, García-Sastre A, Williams BR, Moran TM. Type I interferon induction pathway, but not released interferon, participates in the maturation of dendritic cells induced by negative-strand RNA viruses. The Journal of Infectious Diseases. 187: 1126-36. PMID 12660927 DOI: 10.1086/368381  0.767
2003 Silva M, Lopez C, Menezes J, Cordeiro P, Seidman E. Herpes simplex virus type 1 (HSV-1) infects mature dendritic cells (DCs) in colonic explants from Crohn's disease Gastroenterology. 124: A499. DOI: 10.1016/S0016-5085(03)82528-3  0.584
1986 Kurimura T, Tsuchie H, Kobayashi S, Hinuma Y, Imai J, Lopez CB, Nitiyanant P, Petchclai B, Dominguez CE, Koiman I. Sporadic cases of carriers of human T-lymphotropic virus type 1 in Southeast Asia Japanese Journal of Medical Science and Biology. 39: 25-28. PMID 2874250  0.31
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