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Agnete Kirkeby - Publications

Affiliations: 
Lund University, Lund, Skåne län, Sweden 
Area:
Human embryonic stem cells, Parkinson's Disease, Regenerative therapy, Human neural development
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rifes P, Isaksson M, Rusimbi C, Ramón Santonja A, Nelander J, Laurell T, Kirkeby A. Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells. Stem Cell Research & Therapy. 14: 354. PMID 38072935 DOI: 10.1186/s13287-023-03580-5  0.49
2023 Garza R, Sharma Y, Atacho DAM, Thiruvalluvan A, Abu Hamdeh S, Jönsson ME, Horvath V, Adami A, Ingelsson M, Jern P, Hammell MG, Englund E, Kirkeby A, Jakobsson J, Marklund N. Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia. Cell Reports. 42: 113395. PMID 37967557 DOI: 10.1016/j.celrep.2023.113395  0.623
2023 Kirkeby A, Nelander J, Hoban DB, Rogelius N, Bjartmarz H, Storm P, Fiorenzano A, Adler AF, Vale S, Mudannayake J, Zhang Y, Cardoso T, Mattsson B, Landau AM, Glud AN, et al. Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD. Cell Stem Cell. 30: 1299-1314.e9. PMID 37802036 DOI: 10.1016/j.stem.2023.08.014  0.586
2022 Dubonyte U, Asenjo-Martinez A, Werge T, Lage K, Kirkeby A. Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells. Acta Neuropathologica Communications. 10: 183. PMID 36527106 DOI: 10.1186/s40478-022-01460-2  0.377
2022 Elabi OF, Pass R, Sormonta I, Nolbrant S, Drummond N, Kirkeby A, Kunath T, Parmar M, Lane EL. Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia. Journal of Parkinson's Disease. PMID 35466951 DOI: 10.3233/JPD-212920  0.674
2021 Brambach M, Ernst A, Nolbrant S, Drouin-Ouellet J, Kirkeby A, Parmar M, Olariu V. Neural tube patterning: from a minimal model for rostrocaudal patterning toward an integrated 3D model. Iscience. 24: 102559. PMID 34142058 DOI: 10.1016/j.isci.2021.102559  0.514
2020 Tiklová K, Nolbrant S, Fiorenzano A, Björklund ÅK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lundén-Miguel H, Volakakis N, Kirkeby A, Perlmann T, et al. Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. Nature Communications. 11: 3630. PMID 32669619 DOI: 10.1038/S41467-020-17421-Z  0.641
2020 Rifes P, Isaksson M, Rathore GS, Aldrin-Kirk P, Møller OK, Barzaghi G, Lee J, Egerod KL, Rausch DM, Parmar M, Pers TH, Laurell T, Kirkeby A. Publisher Correction: Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient. Nature Biotechnology. PMID 32528133 DOI: 10.1038/S41587-020-0590-4  0.65
2020 Rifes P, Isaksson M, Rathore GS, Aldrin-Kirk P, Møller OK, Barzaghi G, Lee J, Egerod KL, Rausch DM, Parmar M, Pers TH, Laurell T, Kirkeby A. Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient. Nature Biotechnology. PMID 32451506 DOI: 10.1038/S41587-020-0525-0  0.664
2020 Tiklová K, Nolbrant S, Fiorenzano A, Björklund ÅK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lundén-Miguel H, Volakakis N, Kirkeby A, Perlmann T, et al. Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. Nature Communications. 11: 2434. PMID 32415072 DOI: 10.1038/S41467-020-16225-5  0.715
2020 Korshunova I, Rhein S, García-González D, Stölting I, Pfisterer U, Barta A, Dmytriyeva O, Kirkeby A, Schwaninger M, Khodosevich K. Genetic modification increases the survival and the neuroregenerative properties of transplanted neural stem cells. Jci Insight. PMID 31999645 DOI: 10.1172/Jci.Insight.126268  0.457
2019 Kirkeby A, Barker RA. Parkinson disease and growth factors - is GDNF good enough? Nature Reviews. Neurology. PMID 30948845 DOI: 10.1038/S41582-019-0180-6  0.317
2018 Abbot S, Agbanyo F, Ahlfors JE, Baghbaderani BA, Bartido S, Bharti K, Burke C, Carlsson B, Cavagnaro J, Creasey A, DiGiusto D, Francissen K, Gaffney A, Goldring C, Gorba T, ... ... Kirkeby A, et al. Report of the international conference on manufacturing and testing of pluripotent stem cells. Biologicals : Journal of the International Association of Biological Standardization. PMID 30150108 DOI: 10.1016/J.Biologicals.2018.08.004  0.426
2018 Cardoso T, Adler A, Mattsson B, Hoban DB, Nolbrant S, Nelander Wahlestedt J, Kirkeby A, Grealish S, Björklund A, Parmar M. Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats. The Journal of Comparative Neurology. PMID 30007046 DOI: 10.1002/Cne.24500  0.656
2018 Porrello ER, Kirkeby A. A symphony of stem cells in Vienna - looking to the future. Development (Cambridge, England). 145. PMID 29884655 DOI: 10.1242/Dev.163501  0.449
2017 Lehnen D, Barral S, Cardoso T, Grealish S, Heuer A, Smiyakin A, Kirkeby A, Kollet J, Cremer H, Parmar M, Bosio A, Knöbel S. IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells. Stem Cell Reports. PMID 28943253 DOI: 10.1016/J.Stemcr.2017.08.016  0.731
2017 Nolbrant S, Heuer A, Parmar M, Kirkeby A. Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation. Nature Protocols. 12: 1962-1979. PMID 28858290 DOI: 10.1038/Nprot.2017.078  0.701
2017 Moraghebi R, Kirkeby A, Chaves P, Rönn RE, Sitnicka E, Parmar M, Larsson M, Herbst A, Woods NB. Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications. Stem Cell Research & Therapy. 8: 190. PMID 28841906 DOI: 10.1186/S13287-017-0582-6  0.587
2017 Kirkeby A, Parmar M, Barker RA. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD). Progress in Brain Research. 230: 165-190. PMID 28552228 DOI: 10.1016/Bs.Pbr.2016.11.011  0.652
2017 Kee N, Volakakis N, Kirkeby A, Dahl L, Storvall H, Nolbrant S, Lahti L, Björklund ÅK, Gillberg L, Joodmardi E, Sandberg R, Parmar M, Perlmann T. Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages. Cell Stem Cell. 20: 29-40. PMID 28094018 DOI: 10.1016/J.Stem.2016.10.003  0.698
2017 Kirkeby A, Nolbrant S, Tiklova K, Heuer A, Kee N, Cardoso T, Ottosson DR, Lelos MJ, Rifes P, Dunnett SB, Grealish S, Perlmann T, Parmar M. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease. Cell Stem Cell. 20: 135-148. PMID 28094017 DOI: 10.1016/J.Stem.2016.09.004  0.678
2016 Kirkeby A, Perlmann T, Pereira CF. The stem cell niche finds its true north. Development (Cambridge, England). 143: 2877-81. PMID 27531947 DOI: 10.1242/Dev.140095  0.495
2016 Heuer A, Jönsson ME, Pfisterer U, Kirkeby A, Parmar M. hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation. Experimental Neurology. 282: 78-85. PMID 27235932 DOI: 10.1016/J.Expneurol.2016.05.027  0.776
2016 Barker RA, Parmar M, Kirkeby A, Björklund A, Thompson L, Brundin P. Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016? Journal of Parkinson's Disease. PMID 27003785 DOI: 10.3233/Jpd-160798  0.669
2015 Jönsson ME, Nelander Wahlestedt J, Åkerblom M, Kirkeby A, Malmevik J, Brattaas PL, Jakobsson J, Parmar M. Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor. Development (Cambridge, England). 142: 3166-77. PMID 26395143 DOI: 10.1242/Dev.122747  0.694
2015 Grealish S, Heuer A, Cardoso T, Kirkeby A, Jönsson M, Johansson J, Björklund A, Jakobsson J, Parmar M. Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons. Stem Cell Reports. 4: 975-83. PMID 26004633 DOI: 10.1016/J.Stemcr.2015.04.011  0.759
2014 Grealish S, Diguet E, Kirkeby A, Mattsson B, Heuer A, Bramoulle Y, Van Camp N, Perrier AL, Hantraye P, Björklund A, Parmar M. Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease. Cell Stem Cell. 15: 653-65. PMID 25517469 DOI: 10.1016/J.Stem.2014.09.017  0.677
2013 Moraghebi R, Kirkeby A, Larsson M, Herbst A, Parmar M, Soneji S, Woods N. X-Reactivation Impacts Human iPSC Differentiation Potential Towards Blood Blood. 122: 4838-4838. DOI: 10.1182/Blood.V122.21.4838.4838  0.597
2012 Kirkeby A, Nelander J, Parmar M. Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Frontiers in Cellular Neuroscience. 6: 64. PMID 23316134 DOI: 10.3389/Fncel.2012.00064  0.718
2012 Kirkeby A, Grealish S, Wolf DA, Nelander J, Wood J, Lundblad M, Lindvall O, Parmar M. Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions. Cell Reports. 1: 703-14. PMID 22813745 DOI: 10.1016/J.Celrep.2012.04.009  0.727
2012 Kirkeby A, Parmar M. Building authentic midbrain dopaminergic neurons from stem CEllS - Lessons from development Translational Neuroscience. 3: 314-319. DOI: 10.2478/S13380-012-0041-X  0.711
2011 Pfisterer U, Kirkeby A, Torper O, Wood J, Nelander J, Dufour A, Björklund A, Lindvall O, Jakobsson J, Parmar M. Direct conversion of human fibroblasts to dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 108: 10343-8. PMID 21646515 DOI: 10.1073/Pnas.1105135108  0.658
2010 Sachdeva R, Jönsson ME, Nelander J, Kirkeby A, Guibentif C, Gentner B, Naldini L, Björklund A, Parmar M, Jakobsson J. Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 107: 11602-7. PMID 20534548 DOI: 10.1073/Pnas.1006568107  0.772
2008 Leist M, Bremer S, Brundin P, Hescheler J, Kirkeby A, Krause KH, Poerzgen P, Puceat M, Schmidt M, Schrattenholz A, Zak NB, Hentze H. The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy. Altex. 25: 163-90. PMID 18841314 DOI: 10.14573/Altex.2008.3.163  0.523
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