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Guanhua Xie, Ph.D. - Publications

Affiliations: 
2010 Systems Biology and Disease University of Southern California, Los Angeles, CA, United States 
Area:
Cell Biology, Pathology, Anatomy Biology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Dalton G, Michelotti GA, Chen Y, Xie G, Swiderska-Syn M, Diehl AM. Hedgehog-Dependent yap Signaling Activates Serine Biogenesis and Glutaminolysis to Promote Hepatic Stellate Cell Transdifferentiation Gastroenterology. 152: S559. DOI: 10.1016/S0016-5085(17)32023-1  0.42
2016 Xie G, Wang X, Liu P, Wei R, Chen W, Rajani C, Hernandez BY, Alegado R, Dong B, Li D, Jia W. Distinctly altered gut microbiota in the progression of liver disease. Oncotarget. PMID 27036035 DOI: 10.18632/Oncotarget.8466  0.303
2016 Swiderska-Syn M, Xie G, Michelotti GA, Jewell ML, Premont RT, Syn WK, Diehl AM. Hedgehog regulates Yes-associated protein 1 in regenerating mouse liver. Hepatology (Baltimore, Md.). PMID 26970079 DOI: 10.1002/Hep.28542  0.491
2016 Machado MV, Michelotti GA, Jewell ML, Pereira TA, Xie G, Premont RT, Diehl AM. Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease. Cell Death & Disease. 7: e2096. PMID 26890135 DOI: 10.1038/Cddis.2016.19  0.347
2015 Coombes JD, Choi SS, Swiderska-Syn M, Manka PP, Reid D, Palma E, Briones-Orta MA, Xie G, Younis R, Kitamura N, Della Peruta M, Bitencourt S, Dollé L, Oo YH, Mi Z, et al. Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis. Biochimica Et Biophysica Acta. PMID 26529285 DOI: 10.1016/J.Bbadis.2015.10.028  0.469
2015 Machado MV, Kruger L, Jewell ML, Michelotti GA, Pereira TA, Xie G, Moylan CA, Diehl AM. Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model. Digestive Diseases and Sciences. PMID 26403427 DOI: 10.1007/S10620-015-3871-X  0.421
2015 Pereira TA, Syn WK, MacHado MV, Vidigal PV, Resende V, Voieta I, Xie G, Otoni A, Souza MM, Santos ET, Chan IS, Trindade GV, Choi SS, Witek RP, Pereira FE, et al. Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni. Clinical Science (London, England : 1979). PMID 26201095 DOI: 10.1042/Cs20150117  0.423
2015 Machado MV, Michelotti GA, Pereira TA, Xie G, Premont R, Cortez-Pinto H, Diehl AM. Accumulation of duct cells with activated YAP parallels fibrosis progression in NonAlcoholic Fatty Liver Disease. Journal of Hepatology. PMID 26070409 DOI: 10.1016/J.Jhep.2015.05.031  0.491
2015 Machado MV, Michelotti GA, Xie G, de Almeida TP, Boursier J, Bohnic B, Guy CD, Diehl AM. Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease. Plos One. 10: e0127991. PMID 26017539 DOI: 10.1371/Journal.Pone.0127991  0.362
2015 Karaca G, Xie G, Moylan C, Swiderska-Syn M, Guy CD, Krüger L, Machado MV, Choi SS, Michelotti GA, Burkly LC, Diehl AM. Role of Fn14 in acute alcoholic steatohepatitis in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G325-34. PMID 25524063 DOI: 10.1152/Ajpgi.00429.2013  0.39
2015 Machado MV, Michelotti GA, Pereira Tde A, Boursier J, Kruger L, Swiderska-Syn M, Karaca G, Xie G, Guy CD, Bohinc B, Lindblom KR, Johnson E, Kornbluth S, Diehl AM. Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis. Gut. 64: 1148-57. PMID 25053716 DOI: 10.1136/Gutjnl-2014-307362  0.361
2014 Bohinc BN, Michelotti G, Xie G, Pang H, Suzuki A, Guy CD, Piercy D, Kruger L, Swiderska-Syn M, Machado M, Pereira T, Zavacki AM, Abdelmalek M, Diehl AM. Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism. Endocrinology. 155: 4591-601. PMID 25121996 DOI: 10.1210/En.2014-1302  0.408
2014 Karaca G, Swiderska-Syn M, Xie G, Syn WK, Krüger L, Machado MV, Garman K, Choi SS, Michelotti GA, Burkly LC, Ochoa B, Diehl AM. TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice. Plos One. 9: e83987. PMID 24416188 DOI: 10.1371/Journal.Pone.0083987  0.425
2014 Swiderska-Syn M, Syn WK, Xie G, Krüger L, Machado MV, Karaca G, Michelotti GA, Choi SS, Premont RT, Diehl AM. Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy. Gut. 63: 1333-44. PMID 24173292 DOI: 10.1136/Gutjnl-2013-305962  0.469
2013 Xie G, Diehl AM. Evidence for and against epithelial-to-mesenchymal transition in the liver. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G881-90. PMID 24157970 DOI: 10.1152/Ajpgi.00289.2013  0.489
2013 Xie G, Karaca G, Swiderska-Syn M, Michelotti GA, Krüger L, Chen Y, Premont RT, Choi SS, Diehl AM. Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice. Hepatology (Baltimore, Md.). 58: 1801-13. PMID 23703657 DOI: 10.1002/Hep.26511  0.427
2013 Michelotti GA, Xie G, Swiderska M, Choi SS, Karaca G, Krüger L, Premont R, Yang L, Syn WK, Metzger D, Diehl AM. Smoothened is a master regulator of adult liver repair. The Journal of Clinical Investigation. 123: 2380-94. PMID 23563311 DOI: 10.1172/Jci66904  0.503
2013 Pereira TA, Xie G, Choi SS, Syn WK, Voieta I, Lu J, Chan IS, Swiderska M, Amaral KB, Antunes CM, Secor WE, Witek RP, Lambertucci JR, Pereira FL, Diehl AM. Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni. Liver International : Official Journal of the International Association For the Study of the Liver. 33: 149-61. PMID 23121638 DOI: 10.1111/Liv.12016  0.415
2013 Xie G, Choi SS, Syn WK, Michelotti GA, Swiderska M, Karaca G, Chan IS, Chen Y, Diehl AM. Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation. Gut. 62: 299-309. PMID 22362915 DOI: 10.1136/Gutjnl-2011-301494  0.495
2013 Xie G, Karaca G, Swiderska M, Michelotti GA, Krüger L, Choi SS, Diehl AM. Su1676 Notch Signaling Regulates Hepatic Stellate Cell Fate by Cross-Talking With Hedgehog Signaling Gastroenterology. 144: S-995. DOI: 10.1016/S0016-5085(13)63693-8  0.415
2012 Chan IS, Guy CD, Chen Y, Lu J, Swiderska-Syn M, Michelotti GA, Karaca G, Xie G, Krüger L, Syn WK, Anderson BR, Pereira TA, Choi SS, Baldwin AS, Diehl AM. Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma. Cancer Research. 72: 6344-50. PMID 23066040 DOI: 10.1158/0008-5472.Can-12-1068  0.32
2012 Arzumanyan A, Sambandam V, Clayton MM, Choi SS, Xie G, Diehl AM, Yu DY, Feitelson MA. Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein. Cancer Research. 72: 5912-20. PMID 22986746 DOI: 10.1158/0008-5472.Can-12-2329  0.383
2012 Chen Y, Choi SS, Michelotti GA, Chan IS, Swiderska-Syn M, Karaca GF, Xie G, Moylan CA, Garibaldi F, Premont R, Suliman HB, Piantadosi CA, Diehl AM. Hedgehog controls hepatic stellate cell fate by regulating metabolism. Gastroenterology. 143: 1319-29.e1-11. PMID 22885334 DOI: 10.1053/J.Gastro.2012.07.115  0.432
2012 Syn WK, Agboola KM, Swiderska M, Michelotti GA, Liaskou E, Pang H, Xie G, Philips G, Chan IS, Karaca GF, Pereira Tde A, Chen Y, Mi Z, Kuo PC, Choi SS, et al. NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease. Gut. 61: 1323-9. PMID 22427237 DOI: 10.1136/Gutjnl-2011-301857  0.428
2012 Wang L, Wang X, Xie G, Wang L, Hill CK, DeLeve LD. Liver sinusoidal endothelial cell progenitor cells promote liver regeneration in rats. The Journal of Clinical Investigation. 122: 1567-73. PMID 22406533 DOI: 10.1172/Jci58789  0.675
2012 Xie G, Wang X, Wang L, Wang L, Atkinson RD, Kanel GC, Gaarde WA, Deleve LD. Role of differentiation of liver sinusoidal endothelial cells in progression and regression of hepatic fibrosis in rats. Gastroenterology. 142: 918-927.e6. PMID 22178212 DOI: 10.1053/J.Gastro.2011.12.017  0.665
2010 Xie G, Wang L, Wang X, Wang L, DeLeve LD. Isolation of periportal, midlobular, and centrilobular rat liver sinusoidal endothelial cells enables study of zonated drug toxicity. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G1204-10. PMID 20813915 DOI: 10.1152/Ajpgi.00302.2010  0.623
2010 Xie G, Kanel GC, DeLeve LD. 1 CGMP Signaling Regulates Liver Sinusoidal Endothelial Cell (SEC) Phenotype and Accelerates Reversal of Cirrhosis Gastroenterology. 138: S-773. DOI: 10.1016/S0016-5085(10)63562-7  0.612
2009 Harb R, Xie G, Lutzko C, Guo Y, Wang X, Hill CK, Kanel GC, DeLeve LD. Bone marrow progenitor cells repair rat hepatic sinusoidal endothelial cells after liver injury. Gastroenterology. 137: 704-12. PMID 19447108 DOI: 10.1053/J.Gastro.2009.05.009  0.608
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