| Year |
Citation |
Score |
| 2022 |
Chojnowski JE, Li R, Tsang T, Alfaran FH, Dick A, Cocklin S, Brady DC, Strochlic TI. Copper Modulates the Catalytic Activity of Protein Kinase CK2. Frontiers in Molecular Biosciences. 9: 878652. PMID 35755824 DOI: 10.3389/fmolb.2022.878652 |
0.313 |
|
| 2022 |
Brady DC, Hmeljak J, Dar AC. Understanding and drugging RAS: 40 years to break the tip of the iceberg. Disease Models & Mechanisms. 15. PMID 35244677 DOI: 10.1242/dmm.049519 |
0.307 |
|
| 2020 |
Tsang T, Posimo JM, Gudiel AA, Cicchini M, Feldser DM, Brady DC. Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma. Nature Cell Biology. PMID 32203415 DOI: 10.1038/S41556-020-0481-4 |
0.358 |
|
| 2020 |
Kim YJ, Tsang T, Anderson GR, Posimo JM, Brady DC. Inhibition of BCL2 family members increases the efficacy of copper chelation in BRAFV600E-driven melanoma. Cancer Research. PMID 32005716 DOI: 10.1158/0008-5472.Can-19-1784 |
0.385 |
|
| 2019 |
Rasool RU, Natesan R, Deng Q, Aras S, Lal P, Sander Effron S, Mitchell-Velasquez E, Posimo JM, Carskadon S, Baca SC, Pomerantz MM, Siddiqui J, Schwartz LE, Lee DJ, Palanisamy N, ... ... Brady DC, et al. CDK7 inhibition suppresses Castration-Resistant Prostate Cancer through MED1 inactivation. Cancer Discovery. PMID 31466944 DOI: 10.1158/2159-8290.Cd-19-0189 |
0.307 |
|
| 2019 |
Chung CY, Posimo JM, Lee S, Tsang T, Davis JM, Brady DC, Chang CJ. Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 31451653 DOI: 10.1073/Pnas.1904610116 |
0.337 |
|
| 2019 |
Kim YJ, Bond GJ, Tsang T, Posimo JM, Busino L, Brady DC. Copper chaperone ATOX1 is required for MAPK signaling and growth in BRAF mutation-positive melanoma. Metallomics : Integrated Biometal Science. PMID 31317143 DOI: 10.1039/C9Mt00042A |
0.364 |
|
| 2019 |
Katona BW, Glynn RA, Paulosky KE, Feng Z, Davis CI, Ma J, Berry CT, Szigety KM, Matkar S, Liu Y, Wang H, Wu Y, He X, Freedman BD, Brady DC, et al. Combined menin and EGFR inhibitors synergize to suppress colorectal cancer via EGFR-independent and calcium-mediated repression of SKP2 transcription. Cancer Research. PMID 30877106 DOI: 10.1158/0008-5472.Can-18-2133 |
0.319 |
|
| 2019 |
Rasool R, Natesan R, deng q, Aras S, Lal P, Posimo J, Palanisamy N, Narla G, Den R, Freedman M, brady d, asangani ia. Abstract B016: CDK7 inhibition suppresses AR addicted Castration-Resistant Prostate Cancer through MED1 inactivation Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-B016 |
0.335 |
|
| 2018 |
Sadeghi RS, Kulej K, Kathayat RS, Garcia BA, Dickinson BC, Brady DC, Witze E. Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior. Elife. 7. PMID 29648538 DOI: 10.7554/Elife.34362 |
0.428 |
|
| 2018 |
Sadeghi RS, Kulej K, Kathayat RS, Garcia BA, Dickinson BC, Brady DC, Witze ES. Author response: Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior Elife. DOI: 10.7554/Elife.34362.017 |
0.352 |
|
| 2017 |
Counter CM, Crowe MS, Greenberg DN, Brady DC. Copper Chelation Inhibits BRAFV600E-driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors. Cancer Research. PMID 28986383 DOI: 10.1158/0008-5472.Can-16-1190 |
0.39 |
|
| 2017 |
Rebecca VW, Nicastri MC, McLaughlin N, Fennelly C, McAfee Q, Ronghe A, Nofal M, Lim CY, Witze E, Chude CI, Zhang G, Alicea GM, Piao S, Murugan S, Ojha R, ... ... Brady DC, et al. A unified approach to targeting the lysosome's degradative and growth signaling roles. Cancer Discovery. PMID 28899863 DOI: 10.1158/2159-8290.Cd-17-0741 |
0.346 |
|
| 2016 |
Sammons S, Brady D, Vahdat L, Salama AK. Copper suppression as cancer therapy: the rationale for copper chelating agents in mutated melanoma. Melanoma Management. 3: 207-216. PMID 30190890 DOI: 10.2217/Mmt-2015-0005 |
0.304 |
|
| 2016 |
Chen HY, Brady DC, Villanueva J. Double Trouble: Kinase domain duplication as a new path to drug resistance. Pigment Cell & Melanoma Research. PMID 27399172 DOI: 10.1111/Pcmr.12508 |
0.315 |
|
| 2014 |
Brady DC, Crowe MS, Turski ML, Hobbs GA, Yao X, Chaikuad A, Knapp S, Xiao K, Campbell SL, Thiele DJ, Counter CM. Copper is required for oncogenic BRAF signalling and tumorigenesis. Nature. 509: 492-6. PMID 24717435 DOI: 10.1038/Nature13180 |
0.448 |
|
| 2014 |
Brady DC, Crowe MS, Turski ML, Hobbs GA, Chaikuad A, Knapp S, Campbell SL, Thiele DJ, Counter CM. Abstract 4427: Copper is required for oncogenic BRAF signaling and tumorigenesis Molecular and Cellular Biology. 74: 4427-4427. DOI: 10.1158/1538-7445.Am2014-4427 |
0.428 |
|
| 2013 |
Brady DC, Crowe MS, Turski ML, Thiele DJ, Counter CM. Abstract 4294: Copper is required for oncogenic BRAF signaling and tumorigenesis. Cancer Research. 73: 4294-4294. DOI: 10.1158/1538-7445.Am2013-4294 |
0.314 |
|
| 2012 |
Turski ML, Brady DC, Kim HJ, Kim BE, Nose Y, Counter CM, Winge DR, Thiele DJ. A novel role for copper in Ras/mitogen-activated protein kinase signaling. Molecular and Cellular Biology. 32: 1284-95. PMID 22290441 DOI: 10.1128/Mcb.05722-11 |
0.402 |
|
| 2011 |
Kashatus DF, Lim KH, Brady DC, Pershing NL, Cox AD, Counter CM. RALA and RALBP1 regulate mitochondrial fission at mitosis. Nature Cell Biology. 13: 1108-15. PMID 21822277 DOI: 10.1038/Ncb2310 |
0.54 |
|
| 2010 |
Zipfel PA, Brady DC, Kashatus DF, Ancrile BD, Tyler DS, Counter CM. Ral activation promotes melanomagenesis. Oncogene. 29: 4859-64. PMID 20562921 DOI: 10.1038/Onc.2010.224 |
0.474 |
|
| 2010 |
Lim KH, Brady DC, Kashatus DF, Ancrile BB, Der CJ, Cox AD, Counter CM. Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA. Molecular and Cellular Biology. 30: 508-23. PMID 19901077 DOI: 10.1128/Mcb.00916-08 |
0.658 |
|
| 2009 |
O'Hayer KM, Brady DC, Counter CM. ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis. Carcinogenesis. 30: 1841-7. PMID 19805574 DOI: 10.1093/Carcin/Bgp198 |
0.432 |
|
| 2009 |
Madigan JP, Bodemann BO, Brady DC, Dewar BJ, Keller PJ, Leitges M, Philips MR, Ridley AJ, Der CJ, Cox AD. Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation. The Biochemical Journal. 424: 153-61. PMID 19723022 DOI: 10.1042/Bj20082377 |
0.665 |
|
| 2009 |
Brady DC, Alan JK, Madigan JP, Fanning AS, Cox AD. The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis. Molecular and Cellular Biology. 29: 1035-49. PMID 19064640 DOI: 10.1128/Mcb.00336-08 |
0.657 |
|
| 2006 |
Berzat AC, Brady DC, Fiordalisi JJ, Cox AD. Using inhibitors of prenylation to block localization and transforming activity. Methods in Enzymology. 407: 575-97. PMID 16757354 DOI: 10.1016/S0076-6879(05)07046-1 |
0.577 |
|
| Show low-probability matches. |