| Year |
Citation |
Score |
| 2021 |
Chaudhary S, Ashok A, Wise AS, Rana NA, McDonald D, Kritikos AE, Kong Q, Singh N. Upregulation of brain hepcidin in prion diseases. Prion. 15: 126-137. PMID 34224321 DOI: 10.1080/19336896.2021.1946377 |
0.359 |
|
| 2021 |
Chaudhary S, Ashok A, Wise AS, Rana NA, McDonald D, Kritikos AE, Kong Q, Singh N. Upregulation of brain hepcidin in prion diseases. Prion. 15: 126-137. PMID 34224321 DOI: 10.1080/19336896.2021.1946377 |
0.359 |
|
| 2020 |
Singh N, Chaudhary S, Ashok A, Lindner E. Prions and prion diseases: Insights from the eye. Experimental Eye Research. 108200. PMID 32858007 DOI: 10.1016/J.Exer.2020.108200 |
0.419 |
|
| 2020 |
Ashok A, Chaudhary S, Kritikos AE, Kang MH, McDonald D, Rhee DJ, Singh N. TGFβ2-Hepcidin Feed-Forward Loop in the Trabecular Meshwork Implicates Iron in Glaucomatous Pathology. Investigative Ophthalmology & Visual Science. 61: 24. PMID 32182331 DOI: 10.1167/Iovs.61.3.24 |
0.353 |
|
| 2019 |
Ashok A, Chaudhary S, McDonald D, Kritikos A, Bhargava D, Singh N. Local synthesis of hepcidin in the anterior segment of the eye: A novel observation with physiological and pathological implications. Experimental Eye Research. 107890. PMID 31811823 DOI: 10.1016/J.Exer.2019.107890 |
0.412 |
|
| 2019 |
Ashok A, Kang MH, Wise AS, Pattabiraman P, Johnson WM, Lonigro M, Ravikumar R, Rhee DJ, Singh N. Prion protein modulates endothelial to mesenchyme-like transition in trabecular meshwork cells: Implications for primary open angle glaucoma. Scientific Reports. 9: 13090. PMID 31511544 DOI: 10.1038/S41598-019-49482-6 |
0.454 |
|
| 2018 |
Ashok A, Karmakar S, Chandel R, Ravikumar R, Dalal S, Kong Q, Singh N. Prion protein modulates iron transport in the anterior segment: Implications for ocular iron homeostasis and prion transmission. Experimental Eye Research. PMID 29859760 DOI: 10.1016/J.Exer.2018.05.031 |
0.501 |
|
| 2018 |
Ashok A, Singh N. Prion protein modulates glucose homeostasis by altering intracellular iron. Scientific Reports. 8: 6556. PMID 29700330 DOI: 10.1038/S41598-018-24786-1 |
0.452 |
|
| 2017 |
Baksi S, Singh N. α-Synuclein impairs ferritinophagy in the retinal pigment epithelium: Implications for retinal iron dyshomeostasis in Parkinson's disease. Scientific Reports. 7: 12843. PMID 28993630 DOI: 10.1038/S41598-017-12862-X |
0.36 |
|
| 2017 |
Asthana A, Baksi S, Ashok A, Karmakar S, Mammadova N, Kokemuller R, Greenlee MH, Kong Q, Singh N. Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders. Scientific Reports. 7: 9600. PMID 28851903 DOI: 10.1038/S41598-017-08821-1 |
0.507 |
|
| 2017 |
Tripathi AK, Karmakar S, Asthana A, Ashok A, Desai V, Baksi S, Singh N. Transport of Non-Transferrin Bound Iron to the Brain: Implications for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28550259 DOI: 10.3233/Jad-170097 |
0.381 |
|
| 2016 |
Baksi S, Tripathi AK, Singh N. Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson's disease. Free Radical Biology & Medicine. PMID 27343690 DOI: 10.1016/J.Freeradbiomed.2016.06.025 |
0.41 |
|
| 2016 |
Tripathi AK, Singh N. Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease. Journal of Alzheimer's Disease : Jad. PMID 26836195 DOI: 10.3233/Jad-151039 |
0.47 |
|
| 2015 |
Singh N, Asthana A, Baksi S, Desai V, Haldar S, Hari S, Tripathi AK. The prion-ZIP connection: From cousins to partners in iron uptake. Prion. 9: 420-8. PMID 26689487 DOI: 10.1080/19336896.2015.1118602 |
0.501 |
|
| 2015 |
Dev S, Kumari S, Singh N, Kumar Bal S, Seth P, Mukhopadhyay CK. Role of extracellular Hydrogen peroxide in regulation of iron homeostasis genes in neuronal cells: Implication in iron accumulation. Free Radical Biology & Medicine. 86: 78-89. PMID 26006106 DOI: 10.1016/J.Freeradbiomed.2015.05.025 |
0.404 |
|
| 2015 |
Tripathi AK, Haldar S, Qian J, Beserra A, Suda S, Singh A, Hopfer U, Chen SG, Garrick MD, Turner JR, Knutson MD, Singh N. Prion protein functions as a ferrireductase partner for ZIP14 and DMT1. Free Radical Biology & Medicine. 84: 322-30. PMID 25862412 DOI: 10.1016/J.Freeradbiomed.2015.03.037 |
0.483 |
|
| 2015 |
Haldar S, Tripathi A, Qian J, Beserra A, Suda S, McElwee M, Turner J, Hopfer U, Singh N. Prion protein promotes kidney iron uptake via its ferrireductase activity. The Journal of Biological Chemistry. 290: 5512-22. PMID 25572394 DOI: 10.1074/Jbc.M114.607507 |
0.502 |
|
| 2014 |
Singh N. The role of iron in prion disease and other neurodegenerative diseases. Plos Pathogens. 10: e1004335. PMID 25232824 DOI: 10.1371/Journal.Ppat.1004335 |
0.415 |
|
| 2014 |
Singh N, Haldar S, Tripathi AK, McElwee MK, Horback K, Beserra A. Iron in neurodegenerative disorders of protein misfolding: a case of prion disorders and Parkinson's disease. Antioxidants & Redox Signaling. 21: 471-84. PMID 24512387 DOI: 10.1089/Ars.2014.5874 |
0.481 |
|
| 2014 |
Singh N, Haldar S, Tripathi AK, Horback K, Wong J, Sharma D, Beserra A, Suda S, Anbalagan C, Dev S, Mukhopadhyay CK, Singh A. Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities. Antioxidants & Redox Signaling. 20: 1324-63. PMID 23815406 DOI: 10.1089/Ars.2012.4931 |
0.432 |
|
| 2013 |
Singh A, Haldar S, Horback K, Tom C, Zhou L, Meyerson H, Singh N. Prion protein regulates iron transport by functioning as a ferrireductase. Journal of Alzheimer's Disease : Jad. 35: 541-52. PMID 23478311 DOI: 10.3233/Jad-130218 |
0.468 |
|
| 2013 |
Haldar S, Beveridge 'J, Wong J, Singh A, Galimberti D, Borroni B, Zhu X, Blevins J, Greenlee J, Perry G, Mukhopadhyay CK, Schmotzer C, Singh N. A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD. Antioxidants & Redox Signaling. 19: 1662-75. PMID 23379482 DOI: 10.1089/Ars.2012.5032 |
0.39 |
|
| 2012 |
Singh A, Qing L, Kong Q, Singh N. Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains. Neurobiology of Disease. 45: 930-8. PMID 22182691 DOI: 10.1016/J.Nbd.2011.12.012 |
0.535 |
|
| 2010 |
Li C, Yu S, Nakamura F, Pentikäinen OT, Singh N, Yin S, Xin W, Sy MS. Pro-prion binds filamin A, facilitating its interaction with integrin beta1, and contributes to melanomagenesis. The Journal of Biological Chemistry. 285: 30328-39. PMID 20650901 DOI: 10.1074/Jbc.M110.147413 |
0.349 |
|
| 2010 |
Das D, Luo X, Singh A, Gu Y, Ghosh S, Mukhopadhyay CK, Chen SG, Sy MS, Kong Q, Singh N. Paradoxical role of prion protein aggregates in redox-iron induced toxicity. Plos One. 5: e11420. PMID 20625431 DOI: 10.1371/Journal.Pone.0011420 |
0.551 |
|
| 2010 |
Bhupanapadu Sunkesula SR, Luo X, Das D, Singh A, Singh N. Iron content of ferritin modulates its uptake by intestinal epithelium: implications for co-transport of prions. Molecular Brain. 3: 14. PMID 20429907 DOI: 10.1186/1756-6606-3-14 |
0.47 |
|
| 2010 |
Singh N, Singh A, Das D, Mohan ML. Redox control of prion and disease pathogenesis. Antioxidants & Redox Signaling. 12: 1271-94. PMID 19803746 DOI: 10.1089/Ars.2009.2628 |
0.436 |
|
| 2010 |
Singh N, Das D, Singh A, Mohan ML. Prion protein and metal interaction: physiological and pathological implications. Current Issues in Molecular Biology. 12: 99-107. PMID 19767653 |
0.33 |
|
| 2009 |
Li C, Yu S, Nakamura F, Yin S, Xu J, Petrolla AA, Singh N, Tartakoff A, Abbott DW, Xin W, Sy MS. Binding of pro-prion to filamin A disrupts cytoskeleton and correlates with poor prognosis in pancreatic cancer. The Journal of Clinical Investigation. 119: 2725-36. PMID 19690385 DOI: 10.1172/Jci39542 |
0.426 |
|
| 2009 |
Singh A, Kong Q, Luo X, Petersen RB, Meyerson H, Singh N. Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport. Plos One. 4: e6115. PMID 19568430 DOI: 10.1371/Journal.Pone.0006115 |
0.518 |
|
| 2009 |
Singh A, Isaac AO, Luo X, Mohan ML, Cohen ML, Chen F, Kong Q, Bartz J, Singh N. Abnormal brain iron homeostasis in human and animal prion disorders. Plos Pathogens. 5: e1000336. PMID 19283067 DOI: 10.1371/Journal.Ppat.1000336 |
0.494 |
|
| 2009 |
Singh A, Mohan ML, Isaac AO, Luo X, Petrak J, Vyoral D, Singh N. Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis. Plos One. 4: e4468. PMID 19212444 DOI: 10.1371/Journal.Pone.0004468 |
0.53 |
|
| 2009 |
Singh A, Mohan ML, Isaac AO, Luo X, Petrak J, Vyoral D, Singh N. Correction: Prion Protein Modulates Cellular Iron Uptake: A Novel Function with Implications for Prion Disease Pathogenesis Plos One. 4. DOI: 10.1371/annotation/194f4e44-20f0-48eb-bbe9-14e21d18909b |
0.403 |
|
| 2008 |
Gu Y, Singh A, Bose S, Singh N. Pathogenic mutations in the glycosylphosphatidylinositol signal peptide of PrP modulate its topology in neuroblastoma cells. Molecular and Cellular Neurosciences. 37: 647-56. PMID 18325785 DOI: 10.1016/J.Mcn.2007.08.018 |
0.436 |
|
| 2007 |
Gu Y, Verghese S, Bose S, Mohan M, Singh N. Mutant prion protein D202N associated with familial prion disease is retained in the endoplasmic reticulum and forms 'curly' intracellular aggregates. Journal of Molecular Neuroscience : Mn. 32: 90-6. PMID 17873292 DOI: 10.1007/S12031-007-0023-6 |
0.472 |
|
| 2007 |
Basu S, Mohan ML, Luo X, Kundu B, Kong Q, Singh N. Modulation of proteinase K-resistant prion protein in cells and infectious brain homogenate by redox iron: implications for prion replication and disease pathogenesis. Molecular Biology of the Cell. 18: 3302-12. PMID 17567949 DOI: 10.1091/Mbc.E07-04-0317 |
0.549 |
|
| 2006 |
Gu Y, Luo X, Basu S, Fujioka H, Singh N. Cell-specific metabolism and pathogenesis of transmembrane prion protein. Molecular and Cellular Biology. 26: 2697-715. PMID 16537913 DOI: 10.1128/Mcb.26.7.2697-2715.2006 |
0.452 |
|
| 2004 |
Mishra RS, Basu S, Gu Y, Luo X, Zou WQ, Mishra R, Li R, Chen SG, Gambetti P, Fujioka H, Singh N. Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11280-90. PMID 15601934 DOI: 10.1523/Jneurosci.2864-04.2004 |
0.618 |
|
| 2004 |
Gu Y, Singh N. Doxycycline and protein folding agents rescue the abnormal phenotype of familial CJD H187R in a cell model. Brain Research. Molecular Brain Research. 123: 37-44. PMID 15046864 DOI: 10.1016/J.Molbrainres.2004.01.006 |
0.447 |
|
| 2003 |
Gu Y, Hinnerwisch J, Fredricks R, Kalepu S, Mishra RS, Singh N. Identification of cryptic nuclear localization signals in the prion protein. Neurobiology of Disease. 12: 133-49. PMID 12667468 DOI: 10.1016/S0969-9961(02)00014-1 |
0.424 |
|
| 2003 |
Mishra RS, Bose S, Gu Y, Li R, Singh N. Aggresome formation by mutant prion proteins: the unfolding role of proteasomes in familial prion disorders. Journal of Alzheimer's Disease : Jad. 5: 15-23. PMID 12590162 DOI: 10.3233/Jad-2003-5103 |
0.463 |
|
| 2003 |
Gu Y, Verghese S, Mishra RS, Xu X, Shi Y, Singh N. Mutant prion protein-mediated aggregation of normal prion protein in the endoplasmic reticulum: implications for prion propagation and neurotoxicity. Journal of Neurochemistry. 84: 10-22. PMID 12485397 DOI: 10.1046/J.1471-4159.2003.01255.X |
0.484 |
|
| 2002 |
Mishra RS, Gu Y, Bose S, Verghese S, Kalepu S, Singh N. Cell surface accumulation of a truncated transmembrane prion protein in Gerstmann-Straussler-Scheinker disease P102L. The Journal of Biological Chemistry. 277: 24554-61. PMID 11967261 DOI: 10.1074/Jbc.M200213200 |
0.465 |
|
| 2002 |
Singh N, Gu Y, Bose S, Kalepu S, Mishra RS, Verghese S. Prion peptide 106-126 as a model for prion replication and neurotoxicity. Frontiers in Bioscience : a Journal and Virtual Library. 7: a60-71. PMID 11897566 DOI: 10.2741/Singh |
0.511 |
|
| 2002 |
Gu Y, Fujioka H, Mishra RS, Li R, Singh N. Prion peptide 106-126 modulates the aggregation of cellular prion protein and induces the synthesis of potentially neurotoxic transmembrane PrP. The Journal of Biological Chemistry. 277: 2275-86. PMID 11682469 DOI: 10.1074/Jbc.M104345200 |
0.508 |
|
| 2001 |
Gu Y, Jing Y, Kumar A, Sharma Y, Fujioka H, Singh N. Isolation of human neuronal cells resistant to toxicity by the prion protein peptide 106-126. Journal of Alzheimer's Disease : Jad. 3: 169-180. PMID 12214058 DOI: 10.3233/Jad-2001-3202 |
0.496 |
|
| 2000 |
Jin T, Gu Y, Zanusso G, Sy M, Kumar A, Cohen M, Gambetti P, Singh N. The chaperone protein BiP binds to a mutant prion protein and mediates its degradation by the proteasome. The Journal of Biological Chemistry. 275: 38699-704. PMID 10970892 DOI: 10.1074/Jbc.M005543200 |
0.636 |
|
| 1999 |
Zanusso G, Petersen RB, Jin T, Jing Y, Kanoush R, Ferrari S, Gambetti P, Singh N. Proteasomal degradation and N-terminal protease resistance of the codon 145 mutant prion protein. The Journal of Biological Chemistry. 274: 23396-404. PMID 10438517 DOI: 10.1074/Jbc.274.33.23396 |
0.615 |
|
| 1997 |
Singh N, Zanusso G, Chen SG, Fujioka H, Richardson S, Gambetti P, Petersen RB. Prion protein aggregation reverted by low temperature in transfected cells carrying a prion protein gene mutation. The Journal of Biological Chemistry. 272: 28461-70. PMID 9353306 DOI: 10.1074/Jbc.272.45.28461 |
0.631 |
|
| 1996 |
Singh N, Liang LN, Tykocinski ML, Tartakoff AM. A novel class of cell surface glycolipids of mammalian cells: Free glycosyl phosphatidylinositols Journal of Biological Chemistry. 271: 12879-12884. PMID 8663031 DOI: 10.1074/Jbc.271.22.12879 |
0.334 |
|
| 1994 |
Singh N, Zoeller RA, Tykocinski ML, Lazarow PB, Tartakoff AM. Addition of lipid substituents of mammalian protein glycosylphosphoinositol anchors. Molecular and Cellular Biology. 14: 21-31. PMID 8264589 DOI: 10.1128/Mcb.14.1.21 |
0.351 |
|
| 1992 |
Tartakoff AM, Singh N. How to make a glycoinositol phospholipid anchor Trends in Biochemical Sciences. 17: 470-473. PMID 1455519 DOI: 10.1016/0968-0004(92)90491-Q |
0.41 |
|
| 1991 |
Singh N, Tartakoff AM. Two Different Mutants Blocked in Synthesis of Dolichol-Phosphoryl-Mannose Do Not Add Glycophospholipid Anchors to Membrane Proteins: Quantitative Correction of the Phenotype of a CHO Cell Mutant with Tunicamycin Molecular and Cellular Biology. 11: 391-400. PMID 1986234 DOI: 10.1128/Mcb.11.1.391 |
0.381 |
|
| 1991 |
Singh N, Singleton D, Tartakoff AM. Anchoring and Degradation of Glycolipid-Anchored Membrane Proteins by L929 versus by LM-TK- Mouse Fibroblasts: Implications for Anchor Biosynthesis Molecular and Cellular Biology. 11: 2362-2374. PMID 1826759 DOI: 10.1128/Mcb.11.5.2362 |
0.372 |
|
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