Sergiu P. Pasca - Publications

Affiliations: 
Stanford University, Palo Alto, CA 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Birey F, Pașca SP. Imaging neuronal migration and network activity in human forebrain assembloids. Star Protocols. 3: 101478. PMID 35769932 DOI: 10.1016/j.xpro.2022.101478  0.331
2022 Miura Y, Li MY, Revah O, Yoon SJ, Narazaki G, Pașca SP. Engineering brain assembloids to interrogate human neural circuits. Nature Protocols. PMID 34992269 DOI: 10.1038/s41596-021-00632-z  0.801
2021 Birey F, Li MY, Gordon A, Thete MV, Valencia AM, Revah O, Paşca AM, Geschwind DH, Paşca SP. Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome. Cell Stem Cell. PMID 34990580 DOI: 10.1016/j.stem.2021.11.011  0.776
2021 Panagiotakos G, Pasca SP. A matter of space and time: Emerging roles of disease-associated proteins in neural development. Neuron. PMID 34847355 DOI: 10.1016/j.neuron.2021.10.035  0.733
2021 Kelley KW, Pașca SP. Human brain organogenesis: Toward a cellular understanding of development and disease. Cell. PMID 34774127 DOI: 10.1016/j.cell.2021.10.003  0.314
2021 Roth JG, Huang MS, Li TL, Feig VR, Jiang Y, Cui B, Greely HT, Bao Z, Paşca SP, Heilshorn SC. Advancing models of neural development with biomaterials. Nature Reviews. Neuroscience. PMID 34376834 DOI: 10.1038/s41583-021-00496-y  0.31
2021 Miura Y, Pașca SP. Mapping human brain organoids on a spatial atlas. Cell Stem Cell. 28: 983-984. PMID 34087156 DOI: 10.1016/j.stem.2021.05.004  0.647
2021 Agoglia RM, Sun D, Birey F, Yoon SJ, Miura Y, Sabatini K, Pașca SP, Fraser HB. Primate cell fusion disentangles gene regulatory divergence in neurodevelopment. Nature. PMID 33731928 DOI: 10.1038/s41586-021-03343-3  0.704
2021 Gordon A, Yoon SJ, Tran SS, Makinson CD, Park JY, Andersen J, Valencia AM, Horvath S, Xiao X, Huguenard JR, Pașca SP, Geschwind DH. Long-term maturation of human cortical organoids matches key early postnatal transitions. Nature Neuroscience. PMID 33619405 DOI: 10.1038/s41593-021-00802-y  0.595
2020 Andersen J, Revah O, Miura Y, Thom N, Amin ND, Kelley KW, Singh M, Chen X, Thete MV, Walczak EM, Vogel H, Fan HC, Paşca SP. Generation of Functional Human 3D Cortico-Motor Assembloids. Cell. PMID 33333020 DOI: 10.1016/j.cell.2020.11.017  0.741
2020 Miura Y, Li MY, Birey F, Ikeda K, Revah O, Thete MV, Park JY, Puno A, Lee SH, Porteus MH, Pașca SP. Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells. Nature Biotechnology. 38: 1421-1430. PMID 33273741 DOI: 10.1038/s41587-020-00763-w  0.811
2020 Khan TA, Revah O, Gordon A, Yoon SJ, Krawisz AK, Goold C, Sun Y, Kim CH, Tian Y, Li MY, Schaepe JM, Ikeda K, Amin ND, Sakai N, Yazawa M, et al. Neuronal defects in a human cellular model of 22q11.2 deletion syndrome. Nature Medicine. PMID 32989314 DOI: 10.1038/s41591-020-1043-9  0.726
2020 Teodorescu P, Pasca S, Dima D, Tomuleasa C, Ghiaur G. Targeting the Microenvironment in MDS: The Final Frontier. Frontiers in Pharmacology. 11: 1044. PMID 32742264 DOI: 10.3389/Fphar.2020.01044  0.311
2020 Jurj A, Pasca S, Teodorescu P, Tomuleasa C, Berindan-Neagoe I. Basic knowledge on BCR-ABL1-positive extracellular vesicles. Biomarkers in Medicine. PMID 32270699 DOI: 10.2217/Bmm-2019-0510  0.315
2020 Trevino AE, Sinnott-Armstrong N, Andersen J, Yoon SJ, Huber N, Pritchard JK, Chang HY, Greenleaf WJ, Pașca SP. Chromatin accessibility dynamics in a model of human forebrain development. Science (New York, N.Y.). 367. PMID 31974223 DOI: 10.1126/Science.Aay1645  0.323
2020 Pasca SP. Assembling Three‐Dimensional Models of the Human Brain to Study Development and Disease The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04536  0.382
2019 Marton RM, Pașca SP. Organoid and Assembloid Technologies for Investigating Cellular Crosstalk in Human Brain Development and Disease. Trends in Cell Biology. PMID 31879153 DOI: 10.1016/j.tcb.2019.11.004  0.354
2019 Panagiotakos G, Haveles C, Arjun A, Petrova R, Rana A, Portmann T, Paşca SP, Palmer TD, Dolmetsch RE. Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy Syndrome. Elife. 8. PMID 31868578 DOI: 10.7554/Elife.51037  0.814
2019 Sanders SJ, Sahin M, Hostyk J, Thurm A, Jacquemont S, Avillach P, Douard E, Martin CL, Modi ME, Moreno-De-Luca A, Raznahan A, Anticevic A, Dolmetsch R, Feng G, Geschwind DH, ... ... Pasca SP, et al. A framework for the investigation of rare genetic disorders in neuropsychiatry. Nature Medicine. PMID 31548702 DOI: 10.1038/S41591-019-0581-5  0.636
2019 Geraghty AC, Gibson EM, Ghanem RA, Greene JJ, Ocampo A, Goldstein AK, Ni L, Yang T, Marton RM, Paşca SP, Greenberg ME, Longo FM, Monje M. Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment. Neuron. PMID 31122677 DOI: 10.1016/J.Neuron.2019.04.032  0.475
2019 Pașca AM, Park JY, Shin HW, Qi Q, Revah O, Krasnoff R, O'Hara R, Willsey AJ, Palmer TD, Pașca SP. Human 3D cellular model of hypoxic brain injury of prematurity. Nature Medicine. PMID 31061540 DOI: 10.1038/s41591-019-0436-0  0.78
2019 Arlotta P, Paşca SP. Cell diversity in the human cerebral cortex: from the embryo to brain organoids. Current Opinion in Neurobiology. 56: 194-198. PMID 31051421 DOI: 10.1016/J.Conb.2019.03.001  0.433
2019 Miura Y, Pașca SP. Polarizing brain organoids. Nature Biotechnology. 37: 377-378. PMID 30936565 DOI: 10.1038/S41587-019-0084-4  0.6
2019 Marton RM, Miura Y, Sloan SA, Li Q, Revah O, Levy RJ, Huguenard JR, Pașca SP. Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures. Nature Neuroscience. PMID 30692691 DOI: 10.1038/S41593-018-0316-9  0.789
2019 Paşca SP. Assembling human brain organoids. Science (New York, N.Y.). 363: 126-127. PMID 30630918 DOI: 10.1126/Science.Aau5729  0.36
2019 Yoon SJ, Elahi LS, Pașca AM, Marton RM, Gordon A, Revah O, Miura Y, Walczak EM, Holdgate GM, Fan HC, Huguenard JR, Geschwind DH, Pașca SP. Reliability of human cortical organoid generation. Nature Methods. 16: 75-78. PMID 30573846 DOI: 10.1038/S41592-018-0255-0  0.789
2019 Panagiotakos G, Haveles C, Arjun A, Petrova R, Rana A, Portmann T, Paşca SP, Palmer TD, Dolmetsch RE. Author response: Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome Elife. DOI: 10.7554/Elife.51037.Sa2  0.785
2019 Kratochvil MJ, Seymour AJ, Li TL, Paşca SP, Kuo CJ, Heilshorn SC. Engineered materials for organoid systems Nature Reviews Materials. 4: 606-622. DOI: 10.1038/S41578-019-0129-9  0.316
2019 Pasca S. Assembling Three-Dimensional Models Of The Brain To Study Human Development And Disease European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.07.086  0.383
2019 Pasca S. Three-Dimensional Assembly of The Human Forebrain In Vitro To Study Development and Psychiatric Disorders European Neuropsychopharmacology. 29: S765. DOI: 10.1016/J.Euroneuro.2017.06.123  0.559
2019 Hallmayer J, Bernstein J, O'Hara R, Pasca S. Ipscs - A Platform To Study Autism Spectrum Disorder European Neuropsychopharmacology. 29: S764-S765. DOI: 10.1016/J.Euroneuro.2017.06.121  0.43
2018 Amin ND, Paşca SP. Building Models of Brain Disorders with Three-Dimensional Organoids. Neuron. 100: 389-405. PMID 30359604 DOI: 10.1016/J.Neuron.2018.10.007  0.784
2018 Sloan SA, Andersen J, Pașca AM, Birey F, Pașca SP. Generation and assembly of human brain region-specific three-dimensional cultures. Nature Protocols. PMID 30202107 DOI: 10.1038/S41596-018-0032-7  0.402
2018 Paşca SP. Building three-dimensional human brain organoids. Nature Neuroscience. PMID 29593345 DOI: 10.1038/S41593-018-0107-3  0.349
2018 Marton RM, Paşca SP. A human cellular model of amyotrophic lateral sclerosis. Nature Medicine. 24: 256-257. PMID 29509753 DOI: 10.1038/Nm.4509  0.441
2018 Pașca SP. The rise of three-dimensional human brain cultures. Nature. 553: 437-445. PMID 29364288 DOI: 10.1038/nature25032  0.349
2018 Pasca S, Yoon S. Feeder-free, Xeno-free Generation of Cortical Spheroids From Human Pluripotent Stem Cells Protocol Exchange. DOI: 10.1038/Protex.2018.123  0.43
2017 Khan TA, Paşca SP. The Zika threat to the periphery. Nature Neuroscience. 20: 1191-1192. PMID 28849792 DOI: 10.1038/Nn.4633  0.547
2017 Sloan SA, Darmanis S, Huber N, Khan TA, Birey F, Caneda C, Reimer R, Quake SR, Barres BA, Paşca SP. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells. Neuron. 95: 779-790.e6. PMID 28817799 DOI: 10.1016/J.Neuron.2017.07.035  0.685
2017 Madelaine R, Sloan SA, Huber N, Notwell JH, Leung LC, Skariah G, Halluin C, Paşca SP, Bejerano G, Krasnow MA, Barres BA, Mourrain P. MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis. Cell Reports. 20: 1533-1542. PMID 28813666 DOI: 10.1016/J.Celrep.2017.07.051  0.341
2017 Birey F, Andersen J, Makinson CD, Islam S, Wei W, Huber N, Fan HC, Metzler KRC, Panagiotakos G, Thom N, O'Rourke NA, Steinmetz LM, Bernstein JA, Hallmayer J, Huguenard JR, et al. Assembly of functionally integrated human forebrain spheroids. Nature. PMID 28445465 DOI: 10.1038/Nature22330  0.827
2017 Cao Y, Hjort M, Chen H, Birey F, Leal-Ortiz SA, Han CM, Santiago JG, Paşca SP, Wu JC, Melosh NA. Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223521 DOI: 10.1073/Pnas.1615375114  0.355
2016 Marton RM, Paşca SP. Neural Differentiation in the Third Dimension: Generating a Human Midbrain. Cell Stem Cell. 19: 145-6. PMID 27494668 DOI: 10.1016/J.Stem.2016.07.017  0.461
2016 Sun Y, Paşca SP, Portmann T, Goold C, Worringer KA, Guan W, Chan KC, Gai H, Vogt D, Chen YJ, Mao R, Chan K, Rubenstein JL, Madison DV, Hallmayer J, et al. A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients. Elife. 5. PMID 27458797 DOI: 10.7554/Elife.13073  0.699
2016 Paşca SP. Personalized Human Cortical Spheroids. The American Journal of Psychiatry. 173: 332-3. PMID 27035533 DOI: 10.1176/Appi.Ajp.2016.16020133  0.512
2016 Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, Wu WL, Yang B, Huber N, Pasca SP, Gradinaru V. Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nature Biotechnology. PMID 26829320 DOI: 10.1038/Nbt.3440  0.362
2016 Sun Y, Paşca SP, Portmann T, Goold C, Worringer KA, Guan W, Chan KC, Gai H, Vogt D, Chen YJ, Mao R, Chan K, Rubenstein JL, Madison DV, Hallmayer J, et al. Author response: A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients Elife. DOI: 10.7554/Elife.13073.042  0.643
2016 Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Luo Y, Chan KY, Banerjee A, Wu W, Yang B, Huber N, Pasca SP, Gradinaru V. 252. Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System Molecular Therapy. 24: S99. DOI: 10.1016/S1525-0016(16)33061-1  0.361
2013 Gomez-Ospina N, Panagiotakos G, Portmann T, Pasca SP, Rabah D, Budzillo A, Kinet JP, Dolmetsch RE. A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT. Plos One. 8: e60526. PMID 23613729 DOI: 10.1371/Journal.Pone.0060526  0.772
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