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Matthew Frieman, Ph.D. - Publications

Affiliations: 
1998-2004 Molecular Biology and Genetics Johns Hopkins University, Baltimore, MD 
 2004-2009 Epidemiology University of North Carolina at Chapel Hill School of Medicine 
 2009- Microbiology and Immunology University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Molecular Biology, Microbiology Biology, Virology
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106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jassey A, Logue J, Weston S, Wagner MA, Galitska G, Miller K, Frieman M, Jackson WT. SIRT-1 is required for release of enveloped enteroviruses. Elife. 12. PMID 37850626 DOI: 10.7554/eLife.87993  0.67
2023 Ardanuy J, Johnson R, Dillen C, Taylor L, Hammond H, Weston S, Frieman M. Pyronaridine tetraphosphate is an efficacious antiviral and anti-inflammatory active against multiple highly pathogenic coronaviruses. Mbio. e0158723. PMID 37581442 DOI: 10.1128/mbio.01587-23  0.747
2023 Li M, Ayyanathan K, Dittmar M, Miller J, Tapescu I, Lee JS, McGrath ME, Xue Y, Vashee S, Schultz DC, Frieman MB, Cherry S. SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection. Mbio. e0119423. PMID 37377442 DOI: 10.1128/mbio.01194-23  0.336
2023 Logue J, Melville VM, Ardanuy J, Frieman MB. 2',3' cyclic-nucleotide 3'-phosphodiesterase (CNP) inhibits SARS-CoV-2 virion assembly by blocking infection-induced mitochondria depolarization. Biorxiv : the Preprint Server For Biology. PMID 37333151 DOI: 10.1101/2023.06.09.544327  0.306
2023 Logue J, Johnson RM, Patel N, Zhou B, Maciejewski S, Foreman B, Zhou H, Portnoff AD, Tian JH, Rehman A, McGrath ME, Haupt RE, Weston SM, Baracco L, Hammond H, ... ... Frieman MB, et al. Immunogenicity and protection of a variant nanoparticle vaccine that confers broad neutralization against SARS-CoV-2 variants. Nature Communications. 14: 1130. PMID 36854666 DOI: 10.1038/s41467-022-35606-6  0.784
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Frieman M, et al. Virology under the Microscope-a Call for Rational Discourse. Msphere. e0003423. PMID 36700653 DOI: 10.1128/msphere.00034-23  0.685
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Frieman M, et al. Virology under the Microscope-a Call for Rational Discourse. Mbio. e0018823. PMID 36700642 DOI: 10.1128/mbio.00188-23  0.685
2023 Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Frieman M, et al. Virology under the Microscope-a Call for Rational Discourse. Journal of Virology. e0008923. PMID 36700640 DOI: 10.1128/jvi.00089-23  0.685
2023 Haupt R, Baracco L, Harberts EM, Loganathan M, Kerstetter LJ, Krammer F, Coughlan L, Ernst RK, Frieman MB. Enhancing the protection of influenza virus vaccines with BECC TLR4 adjuvant in aged mice. Scientific Reports. 13: 715. PMID 36639569 DOI: 10.1038/s41598-023-27965-x  0.788
2022 Sajadi MM, Myers A, Logue J, Saadat S, Shokatpour N, Quinn J, Newman M, Deming M, Rikhtegaran Tehrani Z, Magder LS, Karimi M, Abbasi A, Shlyak M, Baracco L, Frieman MB, et al. Mucosal and Systemic Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Determined by Severity of Primary Infection. Msphere. e0027922. PMID 36321826 DOI: 10.1128/msphere.00279-22  0.301
2022 Lai J, Coleman KK, Tai SS, German J, Hong F, Albert B, Esparza Y, Srikakulapu AK, Schanz M, Maldonado IS, Oertel M, Fadul N, Gold TL, Weston S, Mullins K, ... ... Frieman M, et al. Exhaled Breath Aerosol Shedding by Highly Transmissible Versus Prior SARS-CoV-2 Variants. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 36285523 DOI: 10.1093/cid/ciac846  0.693
2022 Jha A, Barker D, Lew J, Manoharan V, van Kessel J, Haupt R, Toth D, Frieman M, Falzarano D, Kodihalli S. Efficacy of COVID-HIGIV in animal models of SARS-CoV-2 infection. Scientific Reports. 12: 16956. PMID 36216961 DOI: 10.1038/s41598-022-21223-2  0.788
2022 Ji Y, Zhang Q, Cheng L, Ge J, Wang R, Fang M, Mucker EM, Chen P, Ma J, Zhang R, Li C, Hammond H, Baracco L, Holbrook M, Frieman M, et al. Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2. Frontiers in Immunology. 13: 980435. PMID 36189212 DOI: 10.3389/fimmu.2022.980435  0.355
2022 Logue J, Chakraborty AR, Johnson R, Goyal G, Rodas M, Taylor LJ, Baracco L, McGrath ME, Haupt R, Furlong BA, Soong M, Prabhala P, Horvath V, Carlson KE, Weston S, ... ... Frieman MB, et al. PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19. Communications Biology. 5: 808. PMID 35962188 DOI: 10.1038/s42003-022-03766-2  0.791
2022 Davenport BJ, Catala A, Weston SM, Johnson RM, Ardanuy J, Hammond HL, Dillen C, Frieman MB, Catalano CE, Morrison TE. Phage-like particle vaccines are highly immunogenic and protect against pathogenic coronavirus infection and disease. Npj Vaccines. 7: 57. PMID 35618725 DOI: 10.1038/s41541-022-00481-1  0.728
2022 DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, et al. Defining the risk of SARS-CoV-2 variants on immune protection. Nature. PMID 35361968 DOI: 10.1038/s41586-022-04690-5  0.759
2022 Schultz DC, Johnson RM, Ayyanathan K, Miller J, Whig K, Kamalia B, Dittmar M, Weston S, Hammond HL, Dillen C, Ardanuy J, Taylor L, Lee JS, Li M, Lee E, ... ... Frieman MB, et al. Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2. Nature. PMID 35130559 DOI: 10.1038/s41586-022-04482-x  0.76
2022 Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Cavazzoni CB, Brook B, Barman S, Chen J, Diray-Arce J, Doss-Gollin S, De Leon M, ... ... Frieman MB, et al. An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice. Science Translational Medicine. 14: eabj5305. PMID 34783582 DOI: 10.1126/scitranslmed.abj5305  0.781
2021 Boras B, Jones RM, Anson BJ, Arenson D, Aschenbrenner L, Bakowski MA, Beutler N, Binder J, Chen E, Eng H, Hammond H, Hammond J, Haupt RE, Hoffman R, Kadar EP, ... ... Frieman MB, et al. Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19. Nature Communications. 12: 6055. PMID 34663813 DOI: 10.1038/s41467-021-26239-2  0.802
2021 Dong J, Zost SJ, Greaney AJ, Starr TN, Dingens AS, Chen EC, Chen RE, Case JB, Sutton RE, Gilchuk P, Rodriguez J, Armstrong E, Gainza C, Nargi RS, Binshtein E, ... ... Frieman MB, et al. Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail. Nature Microbiology. PMID 34548634 DOI: 10.1038/s41564-021-00972-2  0.692
2021 Adenaiye OO, Lai J, de Mesquita PJB, Hong F, Youssefi S, German J, Tai SS, Albert B, Schanz M, Weston S, Hang J, Fung C, Chung HK, Coleman KK, Sapoval N, ... ... Frieman M, et al. Infectious SARS-CoV-2 in Exhaled Aerosols and Efficacy of Masks During Early Mild Infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34519774 DOI: 10.1093/cid/ciab797  0.717
2021 Haupt RE, Harberts EM, Kitz RJ, Strohmeier S, Krammer F, Ernst RK, Frieman MB. Novel TLR4 adjuvant elicits protection against homologous and heterologous Influenza A infection. Vaccine. PMID 34362603 DOI: 10.1016/j.vaccine.2021.06.085  0.781
2021 Schultz DC, Johnson RM, Ayyanathan K, Miller J, Whig K, Kamalia B, Dittmar M, Weston S, Hammond HL, Dillen C, Castellana L, Lee JS, Li M, Lee E, Constant S, ... ... Frieman MB, et al. Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 34189531 DOI: 10.1101/2021.06.24.449811  0.723
2021 Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Brook B, Chen J, Diray-Arce J, Doss-Gollin S, Leon M, Chew K, Menon M, ... ... Frieman MB, et al. Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity. Biorxiv : the Preprint Server For Biology. PMID 34031655 DOI: 10.1101/2021.05.20.444848  0.794
2021 Si L, Bai H, Rodas M, Cao W, Oh CY, Jiang A, Moller R, Hoagland D, Oishi K, Horiuchi S, Uhl S, Blanco-Melo D, Albrecht RA, Liu WC, Jordan T, ... ... Frieman M, et al. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nature Biomedical Engineering. PMID 33941899 DOI: 10.1038/s41551-021-00718-9  0.825
2021 Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Becker ME, Pratt D, Churas C, Rosenthal SB, Liu S, Weston S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, ... ... Frieman MB, et al. Functional landscape of SARS-CoV-2 cellular restriction. Molecular Cell. PMID 33930332 DOI: 10.1016/j.molcel.2021.04.008  0.749
2021 Puhl AC, Fritch EJ, Lane TR, Tse LV, Yount BL, Sacramento CQ, Fintelman-Rodrigues N, Tavella TA, Maranhão Costa FT, Weston S, Logue J, Frieman M, Premkumar L, Pearce KH, Hurst BL, et al. Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: Activity against SARS-CoV-2 and Potential Mechanisms. Acs Omega. 6: 7454-7468. PMID 33778258 DOI: 10.1021/acsomega.0c05996  0.772
2021 Dong J, Zost SJ, Greaney AJ, Starr TN, Dingens AS, Chen EC, Chen RE, Case JB, Sutton RE, Gilchuk P, Rodriguez J, Armstrong E, Gainza C, Nargi RS, Binshtein E, ... ... Frieman MB, et al. Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail. Biorxiv : the Preprint Server For Biology. PMID 33532768 DOI: 10.1101/2021.01.27.428529  0.702
2021 Sivapalasingam S, Saviolakis GA, Kulcsar K, Nakamura A, Conrad T, Hassanein M, Sumner G, Elango C, Kamal MA, Eng S, Kyratsous CA, Musser BJ, Frieman M, Kantrowitz J, Weinreich DM, et al. Human Monoclonal Antibody Cocktail for the Treatment or Prophylaxis of Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV). The Journal of Infectious Diseases. PMID 33507266 DOI: 10.1093/infdis/jiab036  0.802
2021 Tian JH, Patel N, Haupt R, Zhou H, Weston S, Hammond H, Logue J, Portnoff AD, Norton J, Guebre-Xabier M, Zhou B, Jacobson K, Maciejewski S, Khatoon R, Wisniewska M, ... ... Frieman MB, et al. SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice. Nature Communications. 12: 372. PMID 33446655 DOI: 10.1038/s41467-020-20653-8  0.812
2020 Puhl AC, Fritch EJ, Lane TR, Tse LV, Yount BL, Sacramento CQ, Tavella TA, Costa FTM, Weston S, Logue J, Frieman M, Premkumar L, Pearce KH, Hurst BL, Andrade CH, et al. Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms. Biorxiv : the Preprint Server For Biology. PMID 33299990 DOI: 10.1101/2020.12.01.407361  0.768
2020 Weston S, Baracco L, Keller C, Matthews K, McGrath ME, Logue J, Liang J, Dyall J, Holbrook MR, Hensley LE, Jahrling PB, Yu W, MacKerell AD, Frieman MB. The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 33184176 DOI: 10.1073/pnas.2012939117  0.728
2020 Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, ... ... Frieman MB, et al. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science (New York, N.Y.). PMID 33060197 DOI: 10.1126/science.abe9403  0.799
2020 Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Pratt D, Churas C, Rosenthal SB, Liu S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, Pu Y, Oom AL, ... ... Frieman MB, et al. Functional Landscape of SARS-CoV-2 Cellular Restriction. Biorxiv : the Preprint Server For Biology. PMID 33024967 DOI: 10.1101/2020.09.29.319566  0.342
2020 Muñoz-Fontela C, Dowling WE, Funnell SGP, Gsell PS, Balta XR, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, ... ... Frieman MB, et al. Animal models for COVID-19. Nature. PMID 32967005 DOI: 10.1038/s41586-020-2787-6  0.532
2020 Miller K, McGrath ME, Hu Z, Ariannejad S, Weston S, Frieman M, Jackson WT. Coronavirus interactions with the cellular autophagy machinery. Autophagy. 1-9. PMID 32964796 DOI: 10.1080/15548627.2020.1817280  0.735
2020 Keech C, Albert G, Cho I, Robertson A, Reed P, Neal S, Plested JS, Zhu M, Cloney-Clark S, Zhou H, Smith G, Patel N, Frieman MB, Haupt RE, Logue J, et al. Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine. The New England Journal of Medicine. PMID 32877576 DOI: 10.1056/Nejmoa2026920  0.791
2020 Weston S, Frieman M. Using Yeast to Identify Coronavirus-Host Protein Interactions. Methods in Molecular Biology (Clifton, N.J.). 2203: 205-221. PMID 32833214 DOI: 10.1007/978-1-0716-0900-2_15  0.731
2020 Weston S, Coleman CM, Haupt R, Logue J, Matthews K, Li Y, Reyes HM, Weiss SR, Frieman MB. Broad anti-coronaviral activity of FDA approved drugs against SARS-CoV-2 and SARS-CoV . Journal of Virology. PMID 32817221 DOI: 10.1128/Jvi.01218-20  0.805
2020 Sheahan TP, Frieman MB. The continued epidemic threat of SARS-CoV-2 and implications for the future of global public health. Current Opinion in Virology. 40: 37-40. PMID 32569751 DOI: 10.1016/J.Coviro.2020.05.010  0.6
2020 Hansen J, Baum A, Pascal KE, Russo V, Giordano S, Wloga E, Fulton BO, Yan Y, Koon K, Patel K, Chung KM, Hermann A, Ullman E, Cruz J, Rafique A, ... ... Frieman M, et al. Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail. Science (New York, N.Y.). PMID 32540901 DOI: 10.1126/Science.Abd0827  0.79
2020 Weston S, Frieman MB. COVID-19: Knowns, Unknowns, and Questions. Msphere. 5. PMID 32188753 DOI: 10.1128/mSphere.00203-20  0.72
2019 Kulcsar KA, Coleman CM, Beck SE, Frieman MB. Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection. Jci Insight. PMID 31550243 DOI: 10.1172/jci.insight.131774  0.781
2019 Weston S, Matthews KL, Lent R, Vlk A, Haupt R, Kingsbury T, Frieman MB. A yeast suppressor screen used to identify mammalian SIRT1 as a proviral factor for MERS-CoV replication. Journal of Virology. PMID 31142674 DOI: 10.1128/Jvi.00197-19  0.806
2019 Banerjee A, Kulcsar K, Misra V, Frieman M, Mossman K. Bats and Coronaviruses. Viruses. 11. PMID 30634396 DOI: 10.3390/V11010041  0.818
2018 Cong Y, Hart BJ, Gross R, Zhou H, Frieman M, Bollinger L, Wada J, Hensley LE, Jahrling PB, Dyall J, Holbrook MR. MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells. Plos One. 13: e0194868. PMID 29566060 DOI: 10.1371/Journal.Pone.0194868  0.444
2018 Sisk JM, Frieman MB, Machamer CE. Coronavirus S protein-induced fusion is blocked prior to hemifusion by Abl kinase inhibitors. The Journal of General Virology. PMID 29557770 DOI: 10.1099/jgv.0.001047  0.786
2017 Venkataraman T, Coleman C, Frieman M. Overactive EGFR Signaling Leads to Increased Fibrosis After SARS-CoV Infection. Journal of Virology. PMID 28404843 DOI: 10.1128/Jvi.00182-17  0.815
2017 Venkataraman T, Frieman MB. The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis. Antiviral Research. PMID 28390872 DOI: 10.1016/J.Antiviral.2017.03.022  0.781
2017 Coleman CM, Venkataraman T, Liu YV, Glenn GM, Smith GE, Flyer DC, Frieman MB. MERS-CoV spike nanoparticles protect mice from MERS-CoV infection. Vaccine. PMID 28237499 DOI: 10.1016/J.Vaccine.2017.02.012  0.812
2016 Wirblich C, Coleman CM, Kurup D, Abraham TS, Bernbaum JG, Jahrling PB, Hensley LE, Johnson RF, Frieman MB, Schnell MJ. One-Health: A Safe, Efficient Dual-use Vaccine for Humans and Animals against MERS-CoV and Rabies Virus. Journal of Virology. PMID 27807241 DOI: 10.1128/Jvi.02040-16  0.684
2016 Coleman CM, Sisk JM, Halasz G, Zhong J, Beck SE, Matthews KL, Venkataraman T, Rajagopalan S, Kyratsous CA, Frieman MB. CD8+ T cells and Macrophages Regulate Pathogenesis in a Mouse Model of MERS-CoV Disease. Journal of Virology. PMID 27795435 DOI: 10.1128/Jvi.01825-16  0.797
2016 Coleman CM, Sisk JM, Mingo RM, Nelson EA, White JM, Frieman MB. ABL kinase inhibitors are potent inhibitors of SARS-CoV and MERS-CoV fusion. Journal of Virology. PMID 27466418 DOI: 10.1128/Jvi.01429-16  0.816
2016 Luke T, Wu H, Zhao J, Channappanavar R, Coleman CM, Jiao JA, Matsushita H, Liu Y, Postnikova EN, Ork BL, Glenn G, Flyer D, Defang G, Raviprakash K, Kochel T, ... ... Frieman MB, et al. Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Science Translational Medicine. 8: 326ra21. PMID 26888429 DOI: 10.1126/Scitranslmed.Aaf1061  0.675
2016 Sisk JM, Frieman MB. Screening of FDA-Approved Drugs for Treatment of Emerging Pathogens Acs Infectious Diseases. 1: 401-402. DOI: 10.1021/acsinfecdis.5b00089  0.764
2015 Sisk JM, Frieman MB. Screening of FDA-Approved Drugs for Treatment of Emerging Pathogens. Acs Infectious Diseases. 1: 401-2. PMID 27617922 DOI: 10.1021/acsinfecdis.5b00089  0.765
2015 Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, et al. Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross. Plos Genetics. 11: e1005504. PMID 26452100 DOI: 10.1371/Journal.Pgen.1005504  0.738
2015 Taylor JK, Coleman CM, Postel S, Sisk JM, Bernbaum JG, Venkataraman T, Sundberg EJ, Frieman MB. Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference. Journal of Virology. 89: 11820-33. PMID 26378163 DOI: 10.1128/Jvi.02274-15  0.81
2015 Coleman CM, Frieman MB. Growth and Quantification of MERS-CoV Infection. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 64: 15E.2.1-9. PMID 26344222 DOI: 10.1002/9780471729259.mc15e02s37  0.604
2015 Coleman CM, Frieman MB. Growth and Quantification of MERS-CoV Infection. Current Protocols in Microbiology. 37: 15E.2.1-9. PMID 26344219 DOI: 10.1002/9780471729259.mc15e02s37  0.69
2015 Pascal KE, Coleman CM, Mujica AO, Kamat V, Badithe A, Fairhurst J, Hunt C, Strein J, Berrebi A, Sisk JM, Matthews KL, Babb R, Chen G, Lai KV, Huang TT, ... ... Frieman MB, et al. Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124093 DOI: 10.1073/Pnas.1510830112  0.812
2015 McSweegan E, Weaver SC, Lecuit M, Frieman M, Morrison TE, Hrynkow S. The Global Virus Network: Challenging chikungunya. Antiviral Research. 120: 147-52. PMID 26071007 DOI: 10.1016/J.Antiviral.2015.06.003  0.351
2015 Nita-Lazar M, Banerjee A, Feng C, Amin MN, Frieman MB, Chen WH, Cross AS, Wang LX, Vasta GR. Desialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin binding. Molecular Immunology. 65: 1-16. PMID 25597246 DOI: 10.1016/J.Molimm.2014.12.010  0.35
2014 Matthews K, Schäfer A, Pham A, Frieman M. The SARS coronavirus papain like protease can inhibit IRF3 at a post activation step that requires deubiquitination activity. Virology Journal. 11: 209. PMID 25481026 DOI: 10.1186/S12985-014-0209-9  0.372
2014 Coleman CM, Frieman MB. Treating MERS-CoV during an outbreak. The Lancet. Infectious Diseases. 14: 1030-1. PMID 25278219 DOI: 10.1016/S1473-3099(14)70939-9  0.624
2014 Li J, Sun W, Subrahmanyam PB, Page C, Younger KM, Tiper IV, Frieman M, Kimball AS, Webb TJ. NKT Cell Responses to B Cell Lymphoma. Medical Sciences : Open Access Journal. 2: 82-97. PMID 24955247 DOI: 10.3390/Medsci2020082  0.773
2014 Ladner JT, Beitzel B, Chain PS, Davenport MG, Donaldson EF, Frieman M, Kugelman JR, Kuhn JH, O'Rear J, Sabeti PC, Wentworth DE, Wiley MR, Yu GY, Sozhamannan S, et al. Standards for sequencing viral genomes in the era of high-throughput sequencing. Mbio. 5: e01360-14. PMID 24939889 DOI: 10.1128/Mbio.01360-14  0.589
2014 Frieman M. The art of war: battles between virus and host. Current Opinion in Virology. 6: 76-7. PMID 24886699 DOI: 10.1016/J.Coviro.2014.05.001  0.477
2014 Dyall J, Coleman CM, Hart BJ, Venkataraman T, Holbrook MR, Kindrachuk J, Johnson RF, Olinger GG, Jahrling PB, Laidlaw M, Johansen LM, Lear-Rooney CM, Glass PJ, Hensley LE, Frieman MB. Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrobial Agents and Chemotherapy. 58: 4885-93. PMID 24841273 DOI: 10.1128/Aac.03036-14  0.803
2014 Adedeji AO, Singh K, Kassim A, Coleman CM, Elliott R, Weiss SR, Frieman MB, Sarafianos SG. Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses. Antimicrobial Agents and Chemotherapy. 58: 4894-8. PMID 24841268 DOI: 10.1128/AAC.02994-14  0.675
2014 Coleman CM, Liu YV, Mu H, Taylor JK, Massare M, Flyer DC, Glenn GM, Smith GE, Frieman MB. Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice. Vaccine. 32: 3169-74. PMID 24736006 DOI: 10.1016/j.vaccine.2014.04.016  0.773
2014 Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. Journal of Virology. 88: 5209-12. PMID 24600003 DOI: 10.1128/JVI.03488-13  0.694
2014 Matthews KL, Coleman CM, van der Meer Y, Snijder EJ, Frieman MB. The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling. The Journal of General Virology. 95: 874-82. PMID 24443473 DOI: 10.1099/vir.0.062059-0  0.668
2014 Coleman CM, Matthews KL, Goicochea L, Frieman MB. Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus. The Journal of General Virology. 95: 408-12. PMID 24197535 DOI: 10.1099/vir.0.060640-0  0.69
2013 Coleman CM, Frieman MB. Emergence of the Middle East respiratory syndrome coronavirus. Plos Pathogens. 9: e1003595. PMID 24039577 DOI: 10.1371/journal.ppat.1003595  0.63
2012 Page C, Goicochea L, Matthews K, Zhang Y, Klover P, Holtzman MJ, Hennighausen L, Frieman M. Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection. Journal of Virology. 86: 13334-49. PMID 23015710 DOI: 10.1128/Jvi.01689-12  0.807
2012 Huynh J, Li S, Yount B, Smith A, Sturges L, Olsen JC, Nagel J, Johnson JB, Agnihothram S, Gates JE, Frieman MB, Baric RS, Donaldson EF. Evidence supporting a zoonotic origin of human coronavirus strain NL63. Journal of Virology. 86: 12816-25. PMID 22993147 DOI: 10.1128/Jvi.00906-12  0.706
2012 Frieman M, Yount B, Agnihothram S, Page C, Donaldson E, Roberts A, Vogel L, Woodruff B, Scorpio D, Subbarao K, Baric RS. Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease. Journal of Virology. 86: 884-97. PMID 22072787 DOI: 10.1128/Jvi.05957-11  0.812
2012 Chen WH, Toapanta FR, Shirey KA, Zhang L, Giannelou A, Page C, Frieman MB, Vogel SN, Cross AS. Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza. Immunology Letters. 141: 227-34. PMID 22037624 DOI: 10.1016/J.Imlet.2011.10.009  0.803
2011 Frieman M, Basu D, Matthews K, Taylor J, Jones G, Pickles R, Baric R, Engel DA. Yeast based small molecule screen for inhibitors of SARS-CoV. Plos One. 6: e28479. PMID 22164298 DOI: 10.1371/Journal.Pone.0028479  0.711
2011 Peng X, Gralinski L, Ferris MT, Frieman MB, Thomas MJ, Proll S, Korth MJ, Tisoncik JR, Heise M, Luo S, Schroth GP, Tumpey TM, Li C, Kawaoka Y, Baric RS, et al. Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection. Mbio. 2. PMID 22086488 DOI: 10.1128/Mbio.00198-11  0.467
2011 Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Research. 21: 1213-22. PMID 21406540 DOI: 10.1101/Gr.111310.110  0.353
2010 Peng X, Gralinski L, Armour CD, Ferris MT, Thomas MJ, Proll S, Bradel-Tretheway BG, Korth MJ, Castle JC, Biery MC, Bouzek HK, Haynor DR, Frieman MB, Heise M, Raymond CK, et al. Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling. Mbio. 1. PMID 20978541 DOI: 10.1128/Mbio.00206-10  0.528
2010 Donaldson EF, Haskew AN, Gates JE, Huynh J, Moore CJ, Frieman MB. Metagenomic analysis of the viromes of three North American bat species: viral diversity among different bat species that share a common habitat. Journal of Virology. 84: 13004-18. PMID 20926577 DOI: 10.1128/Jvi.01255-10  0.624
2010 Zornetzer GA, Frieman MB, Rosenzweig E, Korth MJ, Page C, Baric RS, Katze MG. Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection. Journal of Virology. 84: 11297-309. PMID 20702617 DOI: 10.1128/Jvi.01130-10  0.814
2010 Frieman MB, Chen J, Morrison TE, Whitmore A, Funkhouser W, Ward JM, Lamirande EW, Roberts A, Heise M, Subbarao K, Baric RS. SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism. Plos Pathogens. 6: e1000849. PMID 20386712 DOI: 10.1371/Journal.Ppat.1000849  0.522
2010 Rockx B, Donaldson E, Frieman M, Sheahan T, Corti D, Lanzavecchia A, Baric RS. Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. The Journal of Infectious Diseases. 201: 946-55. PMID 20144042 DOI: 10.1086/651022  0.797
2010 Freundt EC, Yu L, Goldsmith CS, Welsh S, Cheng A, Yount B, Liu W, Frieman MB, Buchholz UJ, Screaton GR, Lippincott-Schwartz J, Zaki SR, Xu XN, Baric RS, Subbarao K, et al. The open reading frame 3a protein of severe acute respiratory syndrome-associated coronavirus promotes membrane rearrangement and cell death. Journal of Virology. 84: 1097-109. PMID 19889773 DOI: 10.1128/Jvi.01662-09  0.461
2010 Ortiz-Alcantara J, Bhardwaj K, Palaninathan S, Frieman M, Baric RS, Kao CC. Small molecule inhibitors of the SARS-CoV Nsp15 endoribonuclease Virus Adaptation and Treatment. 2: 125-133. DOI: 10.2147/Vaat.S12733  0.495
2009 Day CW, Baric R, Cai SX, Frieman M, Kumaki Y, Morrey JD, Smee DF, Barnard DL. A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo. Virology. 395: 210-22. PMID 19853271 DOI: 10.1016/J.Virol.2009.09.023  0.529
2009 Rockx B, Baas T, Zornetzer GA, Haagmans B, Sheahan T, Frieman M, Dyer MD, Teal TH, Proll S, van den Brand J, Baric R, Katze MG. Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection. Journal of Virology. 83: 7062-74. PMID 19420084 DOI: 10.1128/Jvi.00127-09  0.746
2009 Frieman M, Ratia K, Johnston RE, Mesecar AD, Baric RS. Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling. Journal of Virology. 83: 6689-705. PMID 19369340 DOI: 10.1128/Jvi.02220-08  0.552
2009 Basu D, Walkiewicz MP, Frieman M, Baric RS, Auble DT, Engel DA. Novel influenza virus NS1 antagonists block replication and restore innate immune function. Journal of Virology. 83: 1881-91. PMID 19052087 DOI: 10.1128/Jvi.01805-08  0.59
2009 Rockx B, Baas T, Zornetzer GA, Haagmans B, Sheahan T, Frieman M, Dyer MD, Teal TH, Proll S, Van Den Brand J, Baric R, Katze MG. Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection (Journal of Virology (2009) 83, 14, (7062-7074)) Journal of Virology. 83: 9022. DOI: 10.1128/Jvi.01322-09  0.716
2008 Frieman M, Baric R. Mechanisms of severe acute respiratory syndrome pathogenesis and innate immunomodulation. Microbiology and Molecular Biology Reviews : Mmbr. 72: 672-85, Table of Con. PMID 19052324 DOI: 10.1128/Mmbr.00015-08  0.602
2008 Zupancic ML, Frieman M, Smith D, Alvarez RA, Cummings RD, Cormack BP. Glycan microarray analysis of Candida glabrata adhesin ligand specificity. Molecular Microbiology. 68: 547-59. PMID 18394144 DOI: 10.1111/J.1365-2958.2008.06184.X  0.77
2008 Frieman M, Heise M, Baric R. SARS coronavirus and innate immunity. Virus Research. 133: 101-12. PMID 17451827 DOI: 10.1016/J.Virusres.2007.03.015  0.53
2007 Wathelet MG, Orr M, Frieman MB, Baric RS. Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. Journal of Virology. 81: 11620-33. PMID 17715225 DOI: 10.1128/JVI.00702-07  0.521
2007 Frieman M, Yount B, Heise M, Kopecky-Bromberg SA, Palese P, Baric RS. Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane. Journal of Virology. 81: 9812-24. PMID 17596301 DOI: 10.1128/Jvi.01012-07  0.524
2007 Kopecky-Bromberg SA, Martínez-Sobrido L, Frieman M, Baric RA, Palese P. Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists. Journal of Virology. 81: 548-57. PMID 17108024 DOI: 10.1128/Jvi.01782-06  0.376
2006 Baric RS, Sheahan T, Deming D, Donaldson E, Yount B, Sims AC, Roberts RS, Frieman M, Rockx B. SARS coronavirus vaccine development. Advances in Experimental Medicine and Biology. 581: 553-60. PMID 17037597 DOI: 10.1007/978-0-387-33012-9_101  0.772
2006 Frieman MB, Yount B, Sims AC, Deming DJ, Morrison TE, Sparks J, Denison M, Heise M, Baric RS. SARS coronavirus accessory ORFs encode luxury functions. Advances in Experimental Medicine and Biology. 581: 149-52. PMID 17037522 DOI: 10.1007/978-0-387-33012-9_26  0.786
2005 Yount B, Roberts RS, Sims AC, Deming D, Frieman MB, Sparks J, Denison MR, Davis N, Baric RS. Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. Journal of Virology. 79: 14909-22. PMID 16282490 DOI: 10.1128/Jvi.79.23.14909-14922.2005  0.77
2004 Frieman MB, Cormack BP. Multiple sequence signals determine the distribution of glycosylphosphatidylinositol proteins between the plasma membrane and cell wall in Saccharomyces cerevisiae. Microbiology (Reading, England). 150: 3105-14. PMID 15470092 DOI: 10.1099/Mic.0.27420-0  0.589
2003 Frieman MB, Cormack BP. The omega-site sequence of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae can determine distribution between the membrane and the cell wall. Molecular Microbiology. 50: 883-96. PMID 14617149 DOI: 10.1046/J.1365-2958.2003.03722.X  0.589
2002 Frieman MB, McCaffery JM, Cormack BP. Modular domain structure in the Candida glabrata adhesin Epa1p, a beta1,6 glucan-cross-linked cell wall protein. Molecular Microbiology. 46: 479-92. PMID 12406223 DOI: 10.1046/J.1365-2958.2002.03166.X  0.595
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