Orly Lazarov - Publications

Affiliations: 
Anatomy and Cell Biology University of Illinois at Chicago, Chicago, IL, United States 
Area:
Neuroscience Biology

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Morrissey ZD, Gao J, Shetti A, Li W, Zhan L, Li W, Fortel I, Saido T, Saito T, Ajilore O, Cologna SM, Lazarov O, Leow AD. Temporal alterations in white matter in an knock-in mouse model of Alzheimer's disease. Eneuro. PMID 38290851 DOI: 10.1523/ENEURO.0496-23.2024  0.381
2023 Salta E, Lazarov O, Fitzsimons CP, Tanzi R, Lucassen PJ, Choi SH. Adult hippocampal neurogenesis in Alzheimer's disease: A roadmap to clinical relevance. Cell Stem Cell. 30: 120-136. PMID 36736288 DOI: 10.1016/j.stem.2023.01.002  0.35
2023 Morrissey ZD, Gao J, Zhan L, Li W, Fortel I, Saido T, Saito T, Bakker A, Mackin S, Ajilore O, Lazarov O, Leow AD. Hippocampal functional connectivity across age in an knock-in mouse model of Alzheimer's disease. Frontiers in Aging Neuroscience. 14: 1085989. PMID 36711209 DOI: 10.3389/fnagi.2022.1085989  0.356
2022 Mishra R, Phan T, Kumar P, Morrissey Z, Gupta M, Hollands C, Shetti A, Lopez KL, Maienschein-Cline M, Suh H, Hen R, Lazarov O. Augmenting neurogenesis rescues memory impairments in Alzheimer's disease by restoring the memory-storing neurons. The Journal of Experimental Medicine. 219. PMID 35984475 DOI: 10.1084/jem.20220391  0.388
2021 Disouky A, Lazarov O. Adult hippocampal neurogenesis in Alzheimer's disease. Progress in Molecular Biology and Translational Science. 177: 137-156. PMID 33453939 DOI: 10.1016/bs.pmbts.2020.09.002  0.423
2020 Bonds JA, Shetti A, Stephen TKL, Bonini MG, Minshall RD, Lazarov O. Deficits in hippocampal neurogenesis in obesity-dependent and -independent type-2 diabetes mellitus mouse models. Scientific Reports. 10: 16368. PMID 33004912 DOI: 10.1038/s41598-020-73401-9  0.365
2020 Lazarov O, Minshall RD, Bonini MG. Harnessing neurogenesis in the adult brain-A role in type 2 diabetes mellitus and Alzheimer's disease. International Review of Neurobiology. 155: 235-269. PMID 32854856 DOI: 10.1016/Bs.Irn.2020.03.020  0.496
2019 Bonds JA, Shetti A, Bheri A, Chen Z, Disoukey A, Tai L, Mao M, Head BP, Bonini MG, Haus JM, Minshall RD, Lazarov O. Depletion of Caveolin-1 in Type-2 Diabetes Model Induces Alzheimer's disease Pathology Precursors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31527120 DOI: 10.1523/Jneurosci.0730-19.2019  0.503
2019 Tobin MK, Musaraca K, Disouky A, Shetti A, Bheri A, Honer WG, Kim N, Dawe RJ, Bennett DA, Arfanakis K, Lazarov O. Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients. Cell Stem Cell. PMID 31130513 DOI: 10.1016/J.Stem.2019.05.003  0.447
2019 Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, ... ... Lazarov O, et al. Vascular dysfunction-The disregarded partner of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 15: 158-167. PMID 30642436 DOI: 10.1016/J.Jalz.2018.07.222  0.425
2019 Bartolotti N, Lazarov O. CREB signals as PBMC-based biomarkers of cognitive dysfunction: A novel perspective of the brain-immune axis. Brain, Behavior, and Immunity. PMID 30641141 DOI: 10.1016/J.Bbi.2019.01.004  0.476
2018 Bartolotti N, Disouky A, Kalinski A, Elmann A, Lazarov O. Phytochemicals from Achillea fragrantissima are Modulators of AβPP Metabolism. Journal of Alzheimer's Disease : Jad. PMID 30400087 DOI: 10.3233/Jad-180068  0.477
2018 Elmann A, Telerman A, Ofir R, Kashman Y, Lazarov O. β-amyloid cytotoxicity is prevented by natural achillolide A. Journal of Natural Medicines. PMID 29546477 DOI: 10.1007/S11418-018-1191-0  0.439
2017 Kuttner-Hirshler Y, Venkatasubramanian PN, Apolinario J, Bonds J, Wyrwicz AM, Lazarov O. Brain Biomarkers in Familial Alzheimer's Disease Mouse Models. Journal of Alzheimer's Disease : Jad. PMID 28922152 DOI: 10.3233/Jad-170269  0.569
2017 Hollands C, Tobin MK, Hsu M, Musaraca K, Yu TS, Mishra R, Kernie SG, Lazarov O. Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer's disease by compromising hippocampal inhibition. Molecular Neurodegeneration. 12: 64. PMID 28886753 DOI: 10.1186/S13024-017-0207-7  0.479
2016 Bartolotti N, Bennett DA, Lazarov O. Reduced pCREB in Alzheimer's disease prefrontal cortex is reflected in peripheral blood mononuclear cells. Molecular Psychiatry. PMID 27480489 DOI: 10.1038/Mp.2016.111  0.466
2016 Hollands C, Bartolotti N, Lazarov O. Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms. Frontiers in Neuroscience. 10: 178. PMID 27199641 DOI: 10.3389/Fnins.2016.00178  0.526
2016 Lazarov O, Hollands C. Hippocampal neurogenesis: learning to remember. Progress in Neurobiology. PMID 26855369 DOI: 10.1016/J.Pneurobio.2015.12.006  0.492
2016 Lazarov O, Tesco G. Genes, Environment and Alzheimer's Disease Genes, Environment and Alzheimer's Disease. 1-425.  0.348
2015 Bartolotti N, Segura L, Lazarov O. Diminished CRE-Induced Plasticity is Linked to Memory Deficits in Familial Alzheimer's Disease Mice. Journal of Alzheimer's Disease : Jad. 50: 477-89. PMID 26682682 DOI: 10.3233/Jad-150650  0.481
2015 Bonds JA, Kuttner-Hirshler Y, Bartolotti N, Tobin MK, Pizzi M, Marr R, Lazarov O. Presenilin-1 Dependent Neurogenesis Regulates Hippocampal Learning and Memory. Plos One. 10: e0131266. PMID 26098332 DOI: 10.1371/Journal.Pone.0131266  0.438
2013 Lazarov O, Marr RA. Of mice and men: neurogenesis, cognition and Alzheimer's disease. Frontiers in Aging Neuroscience. 5: 43. PMID 23986699 DOI: 10.3389/Fnagi.2013.00043  0.485
2013 Hu YS, Long N, Pigino G, Brady ST, Lazarov O. Molecular mechanisms of environmental enrichment: impairments in Akt/GSK3β, neurotrophin-3 and CREB signaling. Plos One. 8: e64460. PMID 23700479 DOI: 10.1371/Journal.Pone.0064460  0.618
2013 Demars MP, Hollands C, Zhao Kda T, Lazarov O. Soluble amyloid precursor protein-α rescues age-linked decline in neural progenitor cell proliferation. Neurobiology of Aging. 34: 2431-40. PMID 23683827 DOI: 10.1016/J.Neurobiolaging.2013.04.016  0.447
2013 Kanaan NM, Pigino GF, Brady ST, Lazarov O, Binder LI, Morfini GA. Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system. Experimental Neurology. 246: 44-53. PMID 22721767 DOI: 10.1016/J.Expneurol.2012.06.003  0.425
2012 Little DM, Foxely S, Lazarov O. A preliminary study targeting neuronal pathways activated following environmental enrichment by resting state functional magnetic resonance imaging. Journal of Alzheimer's Disease : Jad. 32: 101-7. PMID 22766734 DOI: 10.3233/Jad-2012-111508  0.441
2012 Lazarov O, Demars MP. All in the Family: How the APPs Regulate Neurogenesis. Frontiers in Neuroscience. 6: 81. PMID 22675290 DOI: 10.3389/Fnins.2012.00081  0.518
2012 Lazarov O, Demars MP, Zhao Kda T, Ali HM, Grauzas V, Kney A, Larson J. Impaired survival of neural progenitor cells in dentate gyrus of adult mice lacking fMRP. Hippocampus. 22: 1220-4. PMID 22128095 DOI: 10.1002/Hipo.20989  0.456
2012 Venkatasubramanian P, Kuttner Y, Aksenov D, Apolinario J, Wyrwicz A, Lazarov O. P4-149: In vivo proton MR spectroscopy of the metabolic effects of familial Alzheimer's-linked mutant variants Alzheimer's & Dementia. 8: P686-P686. DOI: 10.1016/J.Jalz.2012.05.1852  0.344
2011 Demars MP, Bartholomew A, Strakova Z, Lazarov O. Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin. Stem Cell Research & Therapy. 2: 36. PMID 21878106 DOI: 10.1186/Scrt77  0.384
2011 Gadadhar A, Marr R, Lazarov O. Presenilin-1 regulates neural progenitor cell differentiation in the adult brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2615-23. PMID 21325529 DOI: 10.1523/Jneurosci.4767-10.2011  0.383
2011 Jennifer Hu Y, Lazarov O. P4-425: Environmental enrichment modulates Alzheimer's disease pathology via AKT/GSK3ß dependent pathway Alzheimer's & Dementia. 7: e60-e61. DOI: 10.1016/J.Jalz.2011.09.121  0.402
2011 Lazarov O, Gadadhar A, Marr R. P3-191: Alzheimer's disease and neurogenesis: Familial(r) signaling, new roles Alzheimer's & Dementia. 7: S577-S578. DOI: 10.1016/J.Jalz.2011.05.1632  0.378
2010 Lazarov O, Mattson MP, Peterson DA, Pimplikar SW, van Praag H. When neurogenesis encounters aging and disease. Trends in Neurosciences. 33: 569-79. PMID 20961627 DOI: 10.1016/J.Tins.2010.09.003  0.487
2010 Demars M, Hu YS, Gadadhar A, Lazarov O. Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice. Journal of Neuroscience Research. 88: 2103-17. PMID 20209626 DOI: 10.1002/Jnr.22387  0.672
2010 Hu YS, Xu P, Pigino G, Brady ST, Larson J, Lazarov O. Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1667-81. PMID 20086049 DOI: 10.1096/Fj.09-136945  0.661
2010 Perez SE, Berg BM, Moore KA, He B, Counts SE, Fritz JJ, Hu YS, Lazarov O, Lah JJ, Mufson EJ. DHA diet reduces AD pathology in young APPswe/PS1 Delta E9 transgenic mice: possible gender effects. Journal of Neuroscience Research. 88: 1026-40. PMID 19859965 DOI: 10.1002/Jnr.22266  0.599
2010 Lazarov O, Marr RA. Neurogenesis and Alzheimer's disease: at the crossroads. Experimental Neurology. 223: 267-81. PMID 19699201 DOI: 10.1016/J.Expneurol.2009.08.009  0.528
2010 Jennifer Hu Y, Xu P, Pigino G, Brady ST, Larson J, Lazarov O. P2-244: Rescue of impaired neurogenesis and attenuation of neuropathology in FAD-linked transgenic mice by environmental factors Alzheimer's & Dementia. 6: S385-S386. DOI: 10.1016/J.Jalz.2010.05.1293  0.429
2010 Lazarov O. The Molecular Neuropathology of Alzheimer's Disease Principles and Practice of Geriatric Psychiatry: Third Edition. 287-294. DOI: 10.1002/9780470669600.ch49  0.312
2008 Choi SH, Veeraraghavalu K, Lazarov O, Marler S, Ransohoff RM, Ramirez JM, Sisodia SS. Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation. Neuron. 59: 568-80. PMID 18760694 DOI: 10.1016/J.Neuron.2008.07.033  0.505
2008 Gadadhar A, Marr R, Lazarov O. P3-382: The role Of presenilin-1 in adult neurogenesis: Implications for Alzheimer's disease Alzheimer's & Dementia. 4: T633-T633. DOI: 10.1016/J.Jalz.2008.05.1952  0.424
2008 Demars MP, Lazarov O. P3-381: Familial Alzheimer's disease pathology differentially affects discrete neurogenic niches in the adult brain Alzheimer's & Dementia. 4: T633-T633. DOI: 10.1016/J.Jalz.2008.05.1951  0.447
2007 Lazarov O, Morfini GA, Pigino G, Gadadhar A, Chen X, Robinson J, Ho H, Brady ST, Sisodia SS. Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7011-20. PMID 17596450 DOI: 10.1523/Jneurosci.4272-06.2007  0.481
2006 Lazarov O, Peterson LD, Peterson DA, Sisodia SS. Expression of a familial Alzheimer's disease-linked presenilin-1 variant enhances perforant pathway lesion-induced neuronal loss in the entorhinal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 429-34. PMID 16407539 DOI: 10.1523/JNEUROSCI.3961-05.2006  0.373
2005 Unger T, Korade Z, Lazarov O, Terrano D, Schor NF, Sisodia SS, Mirnics K. Transcriptome differences between the frontal cortex and hippocampus of wild-type and humanized presenilin-1 transgenic mice. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 13: 1041-51. PMID 16319296 DOI: 10.1097/00019442-200512000-00003  0.335
2005 Perez SE, Lazarov O, Koprich JB, Chen EY, Rodriguez-Menendez V, Lipton JW, Sisodia SS, Mufson EJ. Nigrostriatal dysfunction in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10220-9. PMID 16267229 DOI: 10.1523/Jneurosci.2773-05.2005  0.479
2005 Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, Lee VM, Hersh LB, Sapolsky RM, Mirnics K, Sisodia SS. Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell. 120: 701-13. PMID 15766532 DOI: 10.1016/J.Cell.2005.01.015  0.38
2005 Mirnics K, Korade Z, Arion D, Lazarov O, Unger T, Macioce M, Sabatini M, Terrano D, Douglass KC, Schor NF, Sisodia SS. Presenilin-1-dependent transcriptome changes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1571-8. PMID 15703411 DOI: 10.1523/Jneurosci.4145-04.2005  0.392
2004 Mirnics K, Mirnics ZK, Portugal CF, Terrano D, Lazarov O, Douglass KC, Lewis DA, Schor NF, Sisodia SS. P4-266 Brain transcriptome changes in presenilin-1 mutant mice Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81824-4  0.389
2004 Mufson EJ, Perez SE, Lazarov O, Rodriguez V, Sisodia S. P2-047 Axonal dystrophy in cholinergic, galaninergic and dopaminergic projection systems in APPSWE/PSIDE9 transgenic mice Neurobiology of Aging. 25: S237. DOI: 10.1016/S0197-4580(04)80794-2  0.315
2004 Lazarov O, Robinson J, Tang Y, Hairston IS, Lee VM, Hersh LB, Sapolsky RM, Sisodia SS. O2-03-01 Reduced amyloid deposition and enhanced Aβ-catabolism in FAD-linked APPSWE/PS1ΔE9 mice following exposure Neurobiology of Aging. 25: S36. DOI: 10.1016/S0197-4580(04)80119-2  0.39
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