Holly M. Brothers - Related publications

Ohio State University, Columbus, Columbus, OH 
Alzheimer's disease
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Kumar N, Sharma N, Khera R, Gupta R, Mehan S. Guggulsterone ameliorates ethidium bromide-induced experimental model of multiple sclerosis via restoration of behavioral, molecular, neurochemical and morphological alterations in rat brain. Metabolic Brain Disease. PMID 33635478 DOI: 10.1007/s11011-021-00691-x   
2021 Dos Santos Cardoso F, Dos Santos JCC, Gonzalez-Lima F, Araújo BHS, Lopes-Martins RÁB, Gomes da Silva S. Effects of Chronic Photobiomodulation with Transcranial Near-Infrared Laser on Brain Metabolomics of Young and Aged Rats. Molecular Neurobiology. PMID 33417219 DOI: 10.1007/s12035-020-02247-z   
2021 El-Missiry MA, Shabana S, Ghazala SJ, Othman AI, Amer ME. Melatonin exerts a neuroprotective effect against γ-radiation-induced brain injury in the rat through the modulation of neurotransmitters, inflammatory cytokines, oxidative stress, and apoptosis. Environmental Science and Pollution Research International. PMID 33598836 DOI: 10.1007/s11356-021-12951-5   
2021 Kaur J, Conti E. Dataset on inflammation induced after lumbar puncture. Data in Brief. 34: 106729. PMID 33521177 DOI: 10.1016/j.dib.2021.106729   
2021 Nalamolu KR, Challa SR, Fornal CA, Grudzien NA, Jorgenson LC, Choudry MM, Smith NJ, Palmer CJ, Pinson DM, Klopfenstein JD, Veeravalli KK. Attenuation of the Induction of TLRs 2 and 4 Mitigates Inflammation and Promotes Neurological Recovery After Focal Cerebral Ischemia. Translational Stroke Research. PMID 33426628 DOI: 10.1007/s12975-020-00884-z   
2021 Nakajima S, Saeki N, Tamano H, Nishio R, Katahira M, Takeuchi A, Takeda A. Age-related vulnerability to nigral dopaminergic degeneration in rats via Zn-permeable GluR2-lacking AMPA receptor activation. Neurotoxicology. 83: 69-76. PMID 33400970 DOI: 10.1016/j.neuro.2020.12.014   
2021 Gao H, Bigalke J, Jiang E, Fan Y, Chen B, Chen QH, Shan Z. TNFα Triggers an Augmented Inflammatory Response in Brain Neurons from Dahl Salt-Sensitive Rats Compared with Normal Sprague Dawley Rats. Cellular and Molecular Neurobiology. PMID 33625627 DOI: 10.1007/s10571-021-01056-9   
2021 Costa AJ, Erustes AG, Sinigaglia R, Girardi CEN, Pereira GJDS, Ureshino RP, Smaili SS. Lack of Autophagy Induction by Lithium Decreases Neuroprotective Effects in the Striatum of Aged Rats. Pharmaceutics. 13. PMID 33494241 DOI: 10.3390/pharmaceutics13020135   
2021 Tiwari V, Mishra A, Singh S, Kumar Mishra S, Kumari Sahu K, Parul, Kulkarni MJ, Shukla R, Shukla S. Protriptyline improves spatial memory and reduces oxidative damage by regulating NFκB-BDNF/CREB signaling axis in streptozotocin-induced rat model of Alzheimer's disease. Brain Research. 147261. PMID 33422534 DOI: 10.1016/j.brainres.2020.147261   
2021 Zhu J, Zhou B, Ma L, Liu L. Exploring the beneficial role of ROCK inhibitors in sepsis-induced cerebral and cognitive injury in rats. Fundamental & Clinical Pharmacology. PMID 33440039 DOI: 10.1111/fcp.12645   
2021 Mi X, Cao Y, Li Y, Li Y, Hong J, He J, Liang Y, Yang N, Liu T, Han D, Kuang C, Han Y, Zhou Y, Liu Y, Shi C, et al. The Non-peptide Angiotensin-(1-7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats. Frontiers in Aging Neuroscience. 13: 624387. PMID 33658918 DOI: 10.3389/fnagi.2021.624387   
2021 Jungling A, Reglodi D, Maasz G, Zrinyi Z, Schmidt J, Rivnyak A, Horvath G, Pirger Z, Tamas A. Alterations of Nigral Dopamine Levels in Parkinson's Disease after Environmental Enrichment and PACAP Treatment in Aging Rats. Life (Basel, Switzerland). 11. PMID 33429934 DOI: 10.3390/life11010035   
2021 Morishima Y, Shibutani T, Noguchi K, Ito Y, Honda Y. Edoxaban, a direct oral factor Xa inhibitor, ameliorates coagulation, microvascular thrombus formation, and acute liver injury in a lipopolysaccharide-induced coagulopathy model in rats. Journal of Thrombosis and Thrombolysis. PMID 33534029 DOI: 10.1007/s11239-021-02381-y   
2021 Lee KH, Kim UJ, Cha M, Lee BH. Chronic Treatment of Ascorbic Acid Leads to Age-Dependent Neuroprotection against Oxidative Injury in Hippocampal Slice Cultures. International Journal of Molecular Sciences. 22. PMID 33562628 DOI: 10.3390/ijms22041608   
2021 Popov A, Brazhe A, Denisov P, Sutyagina O, Li L, Lazareva N, Verkhratsky A, Semyanov A. Astrocyte dystrophy in ageing brain parallels impaired synaptic plasticity. Aging Cell. e13334. PMID 33675569 DOI: 10.1111/acel.13334   
2021 Yang B, Zhao W, Yin C, Bai Y, Wang S, Xing G, Li F, Bian J, Aschner M, Cai J, Shi H, Lu R. Acute acrylonitrile exposure inhibits endogenous HS biosynthesis in rat brain and liver: the role of CBS/3-MPST-HS pathway in its astrocytic toxicity. Toxicology. 152685. PMID 33486070 DOI: 10.1016/j.tox.2021.152685   
2021 Shi Y, Chen X, Liu J, Fan X, Jin Y, Gu J, Liang J, Liang X, Wang C. Isoquercetin Improves Inflammatory Response in Rats Following Ischemic Stroke. Frontiers in Neuroscience. 15: 555543. PMID 33633530 DOI: 10.3389/fnins.2021.555543   
2021 Guo H, Zhu L, Tang P, Chen D, Li Y, Li J, Bao C. Carthamin yellow improves cerebral ischemia‑reperfusion injury by attenuating inflammation and ferroptosis in rats. International Journal of Molecular Medicine. 47. PMID 33576458 DOI: 10.3892/ijmm.2021.4885   
2021 Ferreira RS, Teles-Souza J, Dos Santos Souza C, Pereira ÉPL, de Araújo FM, da Silva AB, Castro E Silva JH, Nonose Y, Núñez-Figueredo Y, de Assis AM, Souza DO, Costa MFD, Moreira JCF, Costa SL, da Silva VDA. Rutin improves glutamate uptake and inhibits glutamate excitotoxicity in rat brain slices. Molecular Biology Reports. PMID 33492574 DOI: 10.1007/s11033-021-06145-y   
2021 Djuretić J, Dimitrijević M, Stojanović M, Stevuljević JK, Hamblin MR, Micov A, Stepanović-Petrović R, Leposavić G. Infrared radiation from cage bedding moderates rat inflammatory and autoimmune responses in collagen-induced arthritis. Scientific Reports. 11: 2882. PMID 33536461 DOI: 10.1038/s41598-021-81999-7   
2021 Chen Z, Chen F, Fang Z, Zhao H, Zhan C, Li C, He Y, Huang C, Long L, Lai K. Glial Activation and Inflammation in the NTS in a Rat Model after Exposure to Diesel Exhaust Particles. Environmental Toxicology and Pharmacology. 103584. PMID 33460804 DOI: 10.1016/j.etap.2021.103584   
2021 Qu Y, Wu JY, Yuan Q. [Effect of acupuncture on hippocampal inflammation in rats with intrauterine distress induced hypoxic-ischemic brain injury]. Zhen Ci Yan Jiu = Acupuncture Research. 46: 14-20. PMID 33559420 DOI: 10.13702/j.1000-0607.200669   
2021 He N, Yu L, Xu M, Huang Y, Wang X, Chen L, Yue S. Near-infrared fluorescent probe for evaluating the acetylcholinesterase effect in the aging process and dietary restriction fluorescence imaging. Journal of Materials Chemistry. B. PMID 33666613 DOI: 10.1039/d0tb02833a   
2021 Clark IA, Vissel B. Broader Insights into Understanding Tumor Necrosis Factor and Neurodegenerative Disease Pathogenesis Infer New Therapeutic Approaches. Journal of Alzheimer's Disease : Jad. PMID 33459706 DOI: 10.3233/JAD-201186   
2021 Pilsner JR, Shershebnev A, Wu H, Marcho C, Dribnokhodova O, Shtratnikova V, Sergeyev O, Suvorov A. Aging-induced changes in sperm DNA methylation are modified by low dose of perinatal flame retardants. Epigenomics. PMID 33401928 DOI: 10.2217/epi-2020-0404   
2021 Yu S, Doycheva DM, Gamdzyk M, Yang Y, Lenahan C, Li G, Li D, Lian L, Tang J, Lu J, Zhang JH. Activation of MC1R with BMS-470539 attenuates neuroinflammation via cAMP/PKA/Nurr1 pathway after neonatal hypoxic-ischemic brain injury in rats. Journal of Neuroinflammation. 18: 26. PMID 33468172 DOI: 10.1186/s12974-021-02078-2   
2021 Li L, Gan H, Jin H, Fang Y, Yang Y, Zhang J, Hu X, Chu L. Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats. International Immunopharmacology. 92: 107335. PMID 33429332 DOI: 10.1016/j.intimp.2020.107335   
2021 Mohammed RA, El-Yamany MF, Abdel-Rahman AA, Nassar NN, Al-Shorbagy MY. Role of pERK1/2-NFκB signaling in the neuroprotective effect of thalidomide against cerebral ischemia reperfusion injury in rats. European Journal of Pharmacology. 895: 173872. PMID 33465355 DOI: 10.1016/j.ejphar.2021.173872   
2021 Zhang H, Zheng Q, Chen-Tsai RY. Establishment of a Cre-rat resource for creating conditional and physiological relevant models of human diseases. Transgenic Research. PMID 33481207 DOI: 10.1007/s11248-020-00226-7   
2021 Jeon H, Bae CH, Lee Y, Kim HY, Kim S. Korean red ginseng suppresses 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced inflammation in the substantia nigra and colon. Brain, Behavior, and Immunity. PMID 33662500 DOI: 10.1016/j.bbi.2021.02.028   
2021 Ragab GH, Halfaya FM, Ahmed OM, Abou El-Kheir W, Mahdi EA, Ali TM, Almehmadi MM, Hagag U. Platelet-Rich Plasma Ameliorates Monosodium Iodoacetate-Induced Ankle Osteoarthritis in the Rat Model via Suppression of Inflammation and Oxidative Stress. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 6692432. PMID 33531920 DOI: 10.1155/2021/6692432   
2021 Pereira PA, Coelho J, Silva A, Madeira MD. Effects of aging on the cholinergic innervation of the rat ventral tegmental area: A stereological study. Experimental Gerontology. 111298. PMID 33652122 DOI: 10.1016/j.exger.2021.111298   
2021 Luhach K, Kulkarni GT, Singh VP, Sharma B. Effect of papaverine on developmental hyperserotonemia induced autism spectrum disorder related behavioural phenotypes by altering markers of neuronal function, inflammation, and oxidative stress in rats. Clinical and Experimental Pharmacology & Physiology. PMID 33480092 DOI: 10.1111/1440-1681.13459   
2021 Soares MSP, Luduvico KP, Chaves VC, Spohr L, Meine BM, Lencina CL, Reginatto FH, Spanevello RM, Simões CMO, Stefanello FM. The Protective Action of Rubus sp. Fruit Extract Against Oxidative Damage in Mice Exposed to Lipopolysaccharide. Neurochemical Research. PMID 33547616 DOI: 10.1007/s11064-021-03248-7   
2021 Xiong LL, Chen J, Du RL, Liu J, Chen YJ, Hawwas MA, Zhou XF, Wang TH, Yang SJ, Bai X. Brain-derived neurotrophic factor and its related enzymes and receptors play important roles after hypoxic-ischemic brain damage. Neural Regeneration Research. 16: 1453-1459. PMID 33433458 DOI: 10.4103/1673-5374.303033   
2021 Chao G, Wang Z, Chen X, Zhang S. Cytokines in the colon, central nervous system and serum of irritable bowel syndrome rats. European Journal of Medical Research. 26: 7. PMID 33441166 DOI: 10.1186/s40001-021-00479-w   
2021 de Souza Cardoso J, Baldissarelli J, Reichert KP, Teixeira FC, Pereira Soares MS, Chitolina Schetinger MR, Morsch VM, Farias Martins Filho AO, Duarte Junior HR, Ribeiro Coriolano FH, Spanevello RM, Stefanello FM, Tavares RG. Neuroprotection elicited by resveratrol in a rat model of hypothyroidism: Possible involvement of cholinergic signaling and redox status. Molecular and Cellular Endocrinology. 524: 111157. PMID 33421531 DOI: 10.1016/j.mce.2021.111157   
2021 Chen X, Xiang X, Xie T, Chen Z, Mou Y, Gao Z, Xie X, Song M, Huang H, Gao Z, Chen M. Memantine protects blood-brain barrier integrity and attenuates neurological deficits through inhibiting nitric oxide synthase ser1412 phosphorylation in intracerebral hemorrhage rats: involvement of peroxynitrite-related matrix metalloproteinase-9/NLRP3 inflammasome activation. Neuroreport. PMID 33470757 DOI: 10.1097/WNR.0000000000001577   
2021 Jantsch MH, Bernardes VM, Oliveira JS, Passos DF, Dornelles GL, Manzoni AG, Cabral FL, da Silva JLG, Schetinger MRC, Leal DBR. Tucumã (Astrocaryum aculeatum) prevents memory loss and oxidative imbalance in the brain of rats with hyperlipidemia. Journal of Food Biochemistry. e13636. PMID 33533491 DOI: 10.1111/jfbc.13636   
2021 Bahadur Patel A, Veeraiah P, Shameem M, Mahesh Kumar J, Saba K. Impaired GABAergic and glutamatergic neurometabolic activity in aged mice brain as measured by H-[ C]-NMR spectroscopy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21321. PMID 33543543 DOI: 10.1096/fj.202001704RR   
2021 Fan W, Zhang Y, Li X, Xu C. S-oxiracetam Facilitates Cognitive Restoration after Ischemic Stroke by Activating α7nAChR and the PI3K-Mediated Pathway. Neurochemical Research. PMID 33481205 DOI: 10.1007/s11064-021-03233-0   
2021 Zhu LF, Wu XY, Liu X, Ma L, Zhang Q, Yu Z, He ZJ, Ying Y, Zhang ZT, Pan XY, Cai YQ, Gong L, He M. [Absence of BAX differentially affects astrocyte density in the mouse cortex and hippocampus]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 73: 1-9. PMID 33665654   
2021 Shi X, Aronson SJ, Ten Bloemendaal L, Duijst S, Bakker RS, de Waart DR, Bortolussi G, Collaud F, Oude Elferink RP, Muro AF, Mingozzi F, Ronzitti G, Bosma PJ. Efficacy of AAV8-h with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients. Molecular Therapy. Methods & Clinical Development. 20: 287-297. PMID 33511243 DOI: 10.1016/j.omtm.2020.11.016   
2021 Wang Z, Li X, Spasojevic I, Lu L, Shen Y, Qu X, Hoffmann U, Warner DS, Paschen W, Sheng H, Yang W. Increasing O-GlcNAcylation is neuroprotective in young and aged brains after ischemic stroke. Experimental Neurology. 113646. PMID 33600817 DOI: 10.1016/j.expneurol.2021.113646   
2021 Rojas A, Amaradhi R, Banik A, Jiang C, Abreu-Melon J, Wang S, Dingledine R, Ganesh T. A Novel Second-Generation EP2 Receptor Antagonist Reduces Neuroinflammation and Gliosis After Status Epilepticus in Rats. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33410110 DOI: 10.1007/s13311-020-00969-5   
2021 Chen F, Hu M, Zhu W, Cao A, Shen Y, Ni B, Qian J, Yang J. Isorhamnetin promotes functional recovery in rats with spinal cord injury by abating oxidative stress and modulating M2 macrophages/microglia polarization. European Journal of Pharmacology. 173878. PMID 33453223 DOI: 10.1016/j.ejphar.2021.173878   
2021 Dong X, Wu W, Yao S, Li H, Li Z, Zhang L, Jiang J, Xu J, Zhang F. PM disrupts thyroid hormone homeostasis through activation of the hypothalamic-pituitary-thyroid (HPT) axis and induction of hepatic transthyretin in female rats 2.5. Ecotoxicology and Environmental Safety. 208: 111720. PMID 33396051 DOI: 10.1016/j.ecoenv.2020.111720   
2021 Granja MG, Alves LP, Leardini-Tristão M, Saul ME, Bortoni LC, de Moraes FM, Ferreira EC, de Moraes BPT, da Silva VZ, Dos Santos AFR, Silva AR, Gonçalves-de-Albuquerque CF, Bambini-Junior V, Weyrich AS, Rondina MT, et al. Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life. Journal of Neuroinflammation. 18: 60. PMID 33632243 DOI: 10.1186/s12974-021-02106-1   
2021 Dumbuya JS, Chen L, Wu JY, Wang B. The role of G-CSF neuroprotective effects in neonatal hypoxic-ischemic encephalopathy (HIE): current status. Journal of Neuroinflammation. 18: 55. PMID 33612099 DOI: 10.1186/s12974-021-02084-4   
2021 Huang GR, Hao FG. Dexmedetomidine Inhibits Inflammation to Alleviate Early Neuronal Injury via TLR4/NF-κB Pathway in Rats with Traumatic Brain Injury. Critical Reviews in Eukaryotic Gene Expression. 31: 41-47. PMID 33639054 DOI: 10.1615/CritRevEukaryotGeneExpr.2021037390