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Loren Looger - Publications

HHMI Janelia Farm Research Campus, Ashburn, VA, United States 
Protein Engineering

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Jensen TP, Zheng K, Cole N, Marvin JS, Looger LL, Rusakov DA. Multiplex imaging relates quantal glutamate release to presynaptic Ca homeostasis at multiple synapses in situ. Nature Communications. 10: 1414. PMID 30926781 DOI: 10.1038/s41467-019-09216-8  0.72
2019 Marvin JS, Scholl B, Wilson DE, Podgorski K, Kazemipour A, Müller JA, Schoch S, Quiroz FJU, Rebola N, Bao H, Little JP, Tkachuk AN, Cai E, Hantman AW, Wang SS, ... ... Looger LL, et al. Author Correction: Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR. Nature Methods. PMID 30820033 DOI: 10.1038/s41592-019-0363-5  0.72
2019 Lobas MA, Tao R, Nagai J, Kronschläger MT, Borden PM, Marvin JS, Looger LL, Khakh BS. A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP. Nature Communications. 10: 711. PMID 30755613 DOI: 10.1038/s41467-019-08441-5  0.72
2019 Marvin JS, Scholl B, Wilson DE, Podgorski K, Kazemipour A, Müller JA, Schoch S, Urra Quiroz FJ, Rebola N, Bao H, Little JP, Tkachuk AN, Cai E, Hantman AW, Wang SS, ... ... Looger LL, et al. Publisher Correction: Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR. Nature Methods. PMID 30602783 DOI: 10.1038/s41592-018-0300-z  0.72
2018 Economo MN, Viswanathan S, Tasic B, Bas E, Winnubst J, Menon V, Graybuck LT, Nguyen TN, Smith KA, Yao Z, Wang L, Gerfen CR, Chandrashekar J, Zeng H, Looger LL, et al. Distinct descending motor cortex pathways and their roles in movement. Nature. 563: 79-84. PMID 30382200 DOI: 10.1038/s41586-018-0642-9  0.68
2018 Tasic B, Yao Z, Graybuck LT, Smith KA, Nguyen TN, Bertagnolli D, Goldy J, Garren E, Economo MN, Viswanathan S, Penn O, Bakken T, Menon V, Miller J, Fong O, ... ... Looger L, et al. Shared and distinct transcriptomic cell types across neocortical areas. Nature. 563: 72-78. PMID 30382198 DOI: 10.1038/s41586-018-0654-5  0.68
2018 Marvin JS, Scholl B, Wilson DE, Podgorski K, Kazemipour A, Müller JA, Schoch S, Quiroz FJU, Rebola N, Bao H, Little JP, Tkachuk AN, Cai E, Hantman AW, Wang SS, ... ... Looger LL, et al. Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR. Nature Methods. PMID 30377363 DOI: 10.1038/s41592-018-0171-3  0.72
2018 Mizuno GO, Wang Y, Shi G, Wang Y, Sun J, Papadopoulos S, Broussard GJ, Unger EK, Deng W, Weick J, Bhattacharyya A, Chen CY, Yu G, Looger LL, Tian L. Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model. Cell Reports. 24: 355-365. PMID 29996097 DOI: 10.1016/j.celrep.2018.06.033  1
2017 Sun Y, Nern A, Franconville R, Dana H, Schreiter ER, Looger LL, Svoboda K, Kim DS, Hermundstad AM, Jayaraman V. Neural signatures of dynamic stimulus selection in Drosophila. Nature Neuroscience. PMID 28604683 DOI: 10.1038/nn.4581  0.84
2017 Kopek BG, Paez-Segala MG, Shtengel G, Sochacki KA, Sun MG, Wang Y, Xu CS, van Engelenburg SB, Taraska JW, Looger LL, Hess HF. Diverse protocols for correlative super-resolution fluorescence imaging and electron microscopy of chemically fixed samples. Nature Protocols. 12: 916-946. PMID 28384138 DOI: 10.1038/nprot.2017.017  0.4
2016 Zolnik TA, Sha F, Johenning F, Schreiter ER, Looger LL, Larkum ME, Sachdev RN. All-optical functional synaptic connectivity mapping in acute brain slices using CaMPARI. The Journal of Physiology. PMID 27861906 DOI: 10.1113/JP273116  0.84
2016 Marvin JS, Looger LL. Falling apart. Elife. 5. PMID 27345573 DOI: 10.7554/eLife.18203  1
2016 Jiang R, Diaz-Castro B, Looger LL, Khakh BS. Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3453-70. PMID 27013675 DOI: 10.1523/JNEUROSCI.3693-15.2016  1
2016 Dana H, Mohar B, Sun Y, Narayan S, Gordus A, Hasseman JP, Tsegaye G, Holt GT, Hu A, Walpita D, Patel R, Macklin JJ, Bargmann CI, Ahrens MB, Schreiter ER, ... ... Looger LL, et al. Sensitive red protein calcium indicators for imaging neural activity. Elife. 5. PMID 27011354 DOI: 10.7554/eLife.12727  1
2016 Sun C, Molineros JE, Looger LL, Zhou XJ, Kim K, Okada Y, Ma J, Qi YY, Kim-Howard X, Motghare P, Bhattarai K, Adler A, Bang SY, Lee HS, Kim TH, et al. High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry. Nature Genetics. PMID 26808113 DOI: 10.1038/ng.3496  1
2015 Beerman RW, Matty MA, Au GG, Looger LL, Choudhury KR, Keller PJ, Tobin DM. Direct In Vivo Manipulation and Imaging of Calcium Transients in Neutrophils Identify a Critical Role for Leading-Edge Calcium Flux. Cell Reports. 13: 2107-17. PMID 26673320 DOI: 10.1016/j.celrep.2015.11.010  1
2015 Henderson MJ, Baldwin HA, Werley CA, Boccardo S, Whitaker LR, Yan X, Holt GT, Schreiter ER, Looger LL, Cohen AE, Kim DS, Harvey BK. A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store. Plos One. 10: e0139273. PMID 26451944 DOI: 10.1371/journal.pone.0139273  1
2015 Ai M, Mills H, Kanai M, Lai J, Deng J, Schreiter E, Looger L, Neubert T, Suh G. Green-to-Red Photoconversion of GCaMP. Plos One. 10: e0138127. PMID 26382605 DOI: 10.1371/journal.pone.0138127  1
2015 Viswanathan S, Williams ME, Bloss EB, Stasevich TJ, Speer CM, Nern A, Pfeiffer BD, Hooks BM, Li WP, English BP, Tian T, Henry GL, Macklin JJ, Patel R, Gerfen CR, ... ... Looger LL, et al. High-performance probes for light and electron microscopy. Nature Methods. 12: 568-76. PMID 25915120 DOI: 10.1038/nmeth.3365  1
2015 Enger R, Tang W, Vindedal GF, Jensen V, Johannes Helm P, Sprengel R, Looger LL, Nagelhus EA. Dynamics of Ionic Shifts in Cortical Spreading Depression. Cerebral Cortex (New York, N.Y. : 1991). PMID 25840424 DOI: 10.1093/cercor/bhv054  1
2015 Tang W, Szokol K, Jensen V, Enger R, Trivedi CA, Hvalby Ø, Helm PJ, Looger LL, Sprengel R, Nagelhus EA. Stimulation-evoked Ca2+ signals in astrocytic processes at hippocampal CA3-CA1 synapses of adult mice are modulated by glutamate and ATP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3016-21. PMID 25698739 DOI: 10.1523/JNEUROSCI.3319-14.2015  1
2015 Fosque BF, Sun Y, Dana H, Yang CT, Ohyama T, Tadross MR, Patel R, Zlatic M, Kim DS, Ahrens MB, Jayaraman V, Looger LL, Schreiter ER. Neural circuits. Labeling of active neural circuits in vivo with designed calcium integrators. Science (New York, N.Y.). 347: 755-60. PMID 25678659 DOI: 10.1126/science.1260922  1
2015 Paez-Segala MG, Sun MG, Shtengel G, Viswanathan S, Baird MA, Macklin JJ, Patel R, Allen JR, Howe ES, Piszczek G, Hess HF, Davidson MW, Wang Y, Looger LL. Fixation-resistant photoactivatable fluorescent proteins for CLEM. Nature Methods. 12: 215-8, 4 p following. PMID 25581799 DOI: 10.1038/nmeth.3225  1
2014 Dana H, Chen TW, Hu A, Shields BC, Guo C, Looger LL, Kim DS, Svoboda K. Thy1-GCaMP6 transgenic mice for neuronal population imaging in vivo. Plos One. 9: e108697. PMID 25250714 DOI: 10.1371/journal.pone.0108697  1
2014 Haga-Yamanaka S, Ma L, He J, Qiu Q, Lavis LD, Looger LL, Yu CR. Integrated action of pheromone signals in promoting courtship behavior in male mice. Elife. 3: e03025. PMID 25073926 DOI: 10.7554/eLife.03025.001  1
2014 Chen M, Lee S, Park SJ, Looger LL, Zhou ZJ. Receptive field properties of bipolar cell axon terminals in direction-selective sublaminas of the mouse retina. Journal of Neurophysiology. 112: 1950-62. PMID 25031256 DOI: 10.1152/jn.00283.2014  1
2014 Borghuis BG, Looger LL, Tomita S, Demb JB. Kainate receptors mediate signaling in both transient and sustained OFF bipolar cell pathways in mouse retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6128-39. PMID 24790183 DOI: 10.1523/JNEUROSCI.4941-13.2014  1
2014 Haustein MD, Kracun S, Lu XH, Shih T, Jackson-Weaver O, Tong X, Xu J, Yang XW, O'Dell TJ, Marvin JS, Ellisman MH, Bushong EA, Looger LL, Khakh BS. Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron. 82: 413-29. PMID 24742463 DOI: 10.1016/j.neuron.2014.02.041  1
2014 Park SJ, Kim IJ, Looger LL, Demb JB, Borghuis BG. Excitatory synaptic inputs to mouse on-off direction-selective retinal ganglion cells lack direction tuning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3976-81. PMID 24623775 DOI: 10.1523/JNEUROSCI.5017-13.2014  1
2014 Maiti AK, Kim-Howard X, Motghare P, Pradhan V, Chua KH, Sun C, Arango-Guerrero MT, Ghosh K, Niewold TB, Harley JB, Anaya JM, Looger LL, Nath SK. Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM. Human Molecular Genetics. 23: 4161-76. PMID 24608226 DOI: 10.1093/hmg/ddu106  1
2014 Kim-Howard X, Sun C, Molineros JE, Maiti AK, Chandru H, Adler A, Wiley GB, Kaufman KM, Kottyan L, Guthridge JM, Rasmussen A, Kelly J, Sánchez E, Raj P, Li QZ, ... ... Looger LL, et al. Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations. Human Molecular Genetics. 23: 1656-68. PMID 24163247 DOI: 10.1093/hmg/ddt532  1
2013 Wardill TJ, Chen TW, Schreiter ER, Hasseman JP, Tsegaye G, Fosque BF, Behnam R, Shields BC, Ramirez M, Kimmel BE, Kerr RA, Jayaraman V, Looger LL, Svoboda K, Kim DS. A neuron-based screening platform for optimizing genetically-encoded calcium indicators. Plos One. 8: e77728. PMID 24155972 DOI: 10.1371/journal.pone.0077728  1
2013 Munger SC, Natarajan A, Looger LL, Ohler U, Capel B. Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of mammalian sex determination. Plos Genetics. 9: e1003630. PMID 23874228 DOI: 10.1371/journal.pgen.1003630  1
2013 Chen TW, Wardill TJ, Sun Y, Pulver SR, Renninger SL, Baohan A, Schreiter ER, Kerr RA, Orger MB, Jayaraman V, Looger LL, Svoboda K, Kim DS. Ultrasensitive fluorescent proteins for imaging neuronal activity. Nature. 499: 295-300. PMID 23868258 DOI: 10.1038/nature12354  1
2013 Borghuis BG, Marvin JS, Looger LL, Demb JB. Two-photon imaging of nonlinear glutamate release dynamics at bipolar cell synapses in the mouse retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10972-85. PMID 23825403 DOI: 10.1523/JNEUROSCI.1241-13.2013  1
2013 Taschenberger G, Toloe J, Tereshchenko J, Akerboom J, Wales P, Benz R, Becker S, Outeiro TF, Looger LL, Bähr M, Zweckstetter M, Kügler S. β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Annals of Neurology. 74: 109-18. PMID 23536356 DOI: 10.1002/ana.23905  1
2013 Looger LL. The Author File: Loren L. Looger. Interview by Vivien Marx. Nature Methods. 10: 93. PMID 23479797 DOI: 10.1038/nmeth.2334  1
2013 Akerboom J, Carreras Calderón N, Tian L, Wabnig S, Prigge M, Tolö J, Gordus A, Orger MB, Severi KE, Macklin JJ, Patel R, Pulver SR, Wardill TJ, Fischer E, Schüler C, ... ... Looger LL, et al. Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics. Frontiers in Molecular Neuroscience. 6: 2. PMID 23459413 DOI: 10.3389/fnmol.2013.00002  1
2013 Molineros JE, Maiti AK, Sun C, Looger LL, Han S, Kim-Howard X, Glenn S, Adler A, Kelly JA, Niewold TB, Gilkeson GS, Brown EE, Alarcón GS, Edberg JC, Petri M, et al. Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. Plos Genetics. 9: e1003222. PMID 23441136 DOI: 10.1371/journal.pgen.1003222  1
2013 Marvin JS, Borghuis BG, Tian L, Cichon J, Harnett MT, Akerboom J, Gordus A, Renninger SL, Chen TW, Bargmann CI, Orger MB, Schreiter ER, Demb JB, Gan WB, Hires SA, ... Looger LL, et al. An optimized fluorescent probe for visualizing glutamate neurotransmission. Nature Methods. 10: 162-70. PMID 23314171 DOI: 10.1038/nmeth.2333  1
2013 Tong X, Shigetomi E, Looger LL, Khakh BS. Genetically encoded calcium indicators and astrocyte calcium microdomains. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 19: 274-91. PMID 23264008 DOI: 10.1177/1073858412468794  1
2012 Chen Q, Cichon J, Wang W, Qiu L, Lee SJ, Campbell NR, Destefino N, Goard MJ, Fu Z, Yasuda R, Looger LL, Arenkiel BR, Gan WB, Feng G. Imaging neural activity using Thy1-GCaMP transgenic mice. Neuron. 76: 297-308. PMID 23083733 DOI: 10.1016/j.neuron.2012.07.011  1
2012 Akerboom J, Chen TW, Wardill TJ, Tian L, Marvin JS, Mutlu S, Calderón NC, Esposti F, Borghuis BG, Sun XR, Gordus A, Orger MB, Portugues R, Engert F, Macklin JJ, ... ... Looger LL, et al. Optimization of a GCaMP calcium indicator for neural activity imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13819-40. PMID 23035093 DOI: 10.1523/JNEUROSCI.2601-12.2012  1
2012 Petreanu L, Gutnisky DA, Huber D, Xu NL, O'Connor DH, Tian L, Looger L, Svoboda K. Activity in motor-sensory projections reveals distributed coding in somatosensation. Nature. 489: 299-303. PMID 22922646 DOI: 10.1038/nature11321  1
2012 Tian L, Hires SA, Looger LL. Imaging neuronal activity with genetically encoded calcium indicators. Cold Spring Harbor Protocols. 2012: 647-56. PMID 22661439 DOI: 10.1101/pdb.top069609  1
2012 Huber D, Gutnisky DA, Peron S, O'Connor DH, Wiegert JS, Tian L, Oertner TG, Looger LL, Svoboda K. Multiple dynamic representations in the motor cortex during sensorimotor learning. Nature. 484: 473-8. PMID 22538608 DOI: 10.1038/nature11039  1
2012 Husson SJ, Costa WS, Wabnig S, Stirman JN, Watson JD, Spencer WC, Akerboom J, Looger LL, Treinin M, Miller DM, Lu H, Gottschalk A. Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors. Current Biology : Cb. 22: 743-52. PMID 22483941 DOI: 10.1016/j.cub.2012.02.066  1
2012 Tian L, Yang Y, Wysocki LM, Arnold AC, Hu A, Ravichandran B, Sternson SM, Looger LL, Lavis LD. Selective esterase-ester pair for targeting small molecules with cellular specificity. Proceedings of the National Academy of Sciences of the United States of America. 109: 4756-61. PMID 22411832 DOI: 10.1073/pnas.1111943109  1
2012 Mütze J, Iyer V, Macklin JJ, Colonell J, Karsh B, Petrášek Z, Schwille P, Looger LL, Lavis LD, Harris TD. Excitation spectra and brightness optimization of two-photon excited probes. Biophysical Journal. 102: 934-44. PMID 22385865 DOI: 10.1016/j.bpj.2011.12.056  1
2012 Zariwala HA, Borghuis BG, Hoogland TM, Madisen L, Tian L, De Zeeuw CI, Zeng H, Looger LL, Svoboda K, Chen TW. A Cre-dependent GCaMP3 reporter mouse for neuronal imaging in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3131-41. PMID 22378886 DOI: 10.1523/JNEUROSCI.4469-11.2012  1
2012 Tian L, Akerboom J, Schreiter ER, Looger LL. Neural activity imaging with genetically encoded calcium indicators. Progress in Brain Research. 196: 79-94. PMID 22341322 DOI: 10.1016/B978-0-444-59426-6.00005-7  1
2012 Lou X, Fan F, Messa M, Raimondi A, Wu Y, Looger LL, Ferguson SM, De Camilli P. Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses. Proceedings of the National Academy of Sciences of the United States of America. 109: E515-23. PMID 22308498 DOI: 10.1073/pnas.1121626109  1
2012 Looger LL. Running in reverse: rhodopsins sense voltage. Nature Methods. 9: 43-4. PMID 22205516 DOI: 10.1038/nmeth.1817  1
2012 Looger LL, Griesbeck O. Genetically encoded neural activity indicators. Current Opinion in Neurobiology. 22: 18-23. PMID 22104761 DOI: 10.1016/j.conb.2011.10.024  1
2012 Akerboom J, Tian L, Marvin JS, Looger LL. Engineering and application of genetically encoded calcium indicators Neuromethods. 72: 125-147. DOI: 10.1007/978-1-62703-014-4-8  1
2011 Alicea I, Marvin JS, Miklos AE, Ellington AD, Looger LL, Schreiter ER. Structure of the Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors. Journal of Molecular Biology. 414: 356-69. PMID 22019591 DOI: 10.1016/j.jmb.2011.09.047  1
2011 Marvin JS, Schreiter ER, Echevarría IM, Looger LL. A genetically encoded, high-signal-to-noise maltose sensor. Proteins. 79: 3025-36. PMID 21989929 DOI: 10.1002/prot.23118  1
2011 Magnus CJ, Lee PH, Atasoy D, Su HH, Looger LL, Sternson SM. Chemical and genetic engineering of selective ion channel-ligand interactions. Science (New York, N.Y.). 333: 1292-6. PMID 21885782 DOI: 10.1126/science.1206606  1
2011 Mittmann W, Wallace DJ, Czubayko U, Herb JT, Schaefer AT, Looger LL, Denk W, Kerr JN. Two-photon calcium imaging of evoked activity from L5 somatosensory neurons in vivo. Nature Neuroscience. 14: 1089-93. PMID 21743473 DOI: 10.1038/nn.2879  1
2011 Borghuis BG, Tian L, Xu Y, Nikonov SS, Vardi N, Zemelman BV, Looger LL. Imaging light responses of targeted neuron populations in the rodent retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2855-67. PMID 21414907 DOI: 10.1523/JNEUROSCI.6064-10.2011  1
2011 Hampel S, Chung P, McKellar CE, Hall D, Looger LL, Simpson JH. Drosophila Brainbow: a recombinase-based fluorescence labeling technique to subdivide neural expression patterns. Nature Methods. 8: 253-9. PMID 21297621 DOI: 10.1038/nmeth.1566  1
2010 Ruta V, Datta SR, Vasconcelos ML, Freeland J, Looger LL, Axel R. A dimorphic pheromone circuit in Drosophila from sensory input to descending output. Nature. 468: 686-90. PMID 21124455 DOI: 10.1038/nature09554  1
2010 Xiang Y, Yuan Q, Vogt N, Looger LL, Jan LY, Jan YN. Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall. Nature. 468: 921-6. PMID 21068723 DOI: 10.1038/nature09576  1
2010 Del Bene F, Wyart C, Robles E, Tran A, Looger L, Scott EK, Isacoff EY, Baier H. Filtering of visual information in the tectum by an identified neural circuit. Science (New York, N.Y.). 330: 669-73. PMID 21030657 DOI: 10.1126/science.1192949  1
2010 Dombeck DA, Harvey CD, Tian L, Looger LL, Tank DW. Functional imaging of hippocampal place cells at cellular resolution during virtual navigation. Nature Neuroscience. 13: 1433-40. PMID 20890294 DOI: 10.1038/nn.2648  1
2010 Cheng LE, Song W, Looger LL, Jan LY, Jan YN. The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron. 67: 373-80. PMID 20696376 DOI: 10.1016/j.neuron.2010.07.004  1
2010 Tang J, Akerboom J, Vaziri A, Looger LL, Shank CV. Near-isotropic 3D optical nanoscopy with photon-limited chromophores. Proceedings of the National Academy of Sciences of the United States of America. 107: 10068-73. PMID 20472826 DOI: 10.1073/pnas.1004899107  1
2009 Tian L, Hires SA, Mao T, Huber D, Chiappe ME, Chalasani SH, Petreanu L, Akerboom J, McKinney SA, Schreiter ER, Bargmann CI, Jayaraman V, Svoboda K, Looger LL. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nature Methods. 6: 875-81. PMID 19898485 DOI: 10.1038/nmeth.1398  1
2009 Kim CS, Pierre B, Ostermeier M, Looger LL, Kim JR. Enzyme stabilization by domain insertion into a thermophilic protein. Protein Engineering, Design & Selection : Peds. 22: 615-23. PMID 19622545 DOI: 10.1093/protein/gzp044  1
2009 McKinney SA, Murphy CS, Hazelwood KL, Davidson MW, Looger LL. A bright and photostable photoconvertible fluorescent protein. Nature Methods. 6: 131-3. PMID 19169260 DOI: 10.1038/nmeth.1296  1
2009 Akerboom J, Rivera JD, Guilbe MM, Malavé EC, Hernandez HH, Tian L, Hires SA, Marvin JS, Looger LL, Schreiter ER. Crystal structures of the GCaMP calcium sensor reveal the mechanism of fluorescence signal change and aid rational design. The Journal of Biological Chemistry. 284: 6455-64. PMID 19098007 DOI: 10.1074/jbc.M807657200  1
2009 Tang J, Vaziri A, Akerboom JP, Looger L, Shank CV. Three dimensional super resolution fluorescence imaging of single bacterial cells by stereo photoactivated localization microscopy Microscopy and Microanalysis. 15: 564-565. DOI: 10.1017/S1431927609095737  1
2009 Machielsen R, Looger LL, Raedts J, Dijkhuizen S, Hummel W, Henneman HG, Daussmann T, van der Oost J. Cofactor engineering of Lactobacillus brevis alcohol dehydrogenase by computational design Engineering in Life Sciences. 9: 38-44. DOI: 10.1002/elsc.200800046  1
2008 Tian L, Looger LL. Genetically encoded fluorescent sensors for studying healthy and diseased nervous systems. Drug Discovery Today. Disease Models. 5: 27-35. PMID 19461949 DOI: 10.1016/j.ddmod.2008.07.003  1
2008 Hires SA, Tian L, Looger LL. Reporting neural activity with genetically encoded calcium indicators. Brain Cell Biology. 36: 69-86. PMID 18941901 DOI: 10.1007/s11068-008-9029-4  1
2008 Rodríguez Guilbe MM, Alfaro Malavé EC, Akerboom J, Marvin JS, Looger LL, Schreiter ER. Crystallization and preliminary X-ray characterization of the genetically encoded fluorescent calcium indicator protein GCaMP2. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 629-31. PMID 18607093 DOI: 10.1107/S1744309108016059  1
2008 Kaper T, Lager I, Looger LL, Chermak D, Frommer WB. Fluorescence resonance energy transfer sensors for quantitative monitoring of pentose and disaccharide accumulation in bacteria. Biotechnology For Biofuels. 1: 11. PMID 18522753 DOI: 10.1186/1754-6834-1-11  1
2008 Dwyer MA, Looger LL, Hellinga HW. Retraction. Science (New York, N.Y.). 319: 569. PMID 18239106 DOI: 10.1126/science.319.5863.569b  1
2007 Kaper T, Looger LL, Takanaga H, Platten M, Steinman L, Frommer WB. Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle. Plos Biology. 5: e257. PMID 17896864 DOI: 10.1371/journal.pbio.0050257  1
2007 Trisler K, Looger LL, Sharma V, Baker M, Benson DE, Trauger S, Schultz PG, Smider VV. A metalloantibody that irreversibly binds a protein antigen. The Journal of Biological Chemistry. 282: 26344-53. PMID 17617633 DOI: 10.1074/jbc.M704675200  1
2007 Loqué D, Lalonde S, Looger LL, von Wirén N, Frommer WB. A cytosolic trans-activation domain essential for ammonium uptake. Nature. 446: 195-8. PMID 17293878 DOI: 10.1038/nature05579  1
2007 Machielsen R, Dijkhuizen S, Van Der Oost J, Kaper T, Looger L. Improving enzyme performance in food applications Novel Enzyme Technology For Food Applications. 16-42. DOI: 10.1533/9781845693718.1.16  1
2007 Gu H, Lalonde S, Okumoto S, Looger LL, Scharff-Poulsen AM, Grossman AR, Kossmann J, Jakobsen I, Frommer WB. Corrigendum to "A novel analytical method for in vivo phosphate tracking" [FEBS Lett. 580 (2006) 5885-5893] (DOI:10.1016/j.febslet.2006.09.048) Febs Letters. 581: 579. DOI: 10.1016/j.febslet.2007.01.002  1
2006 Gu H, Lalonde S, Okumoto S, Looger LL, Scharff-Poulsen AM, Grossman AR, Kossmann J, Jakobsen I, Frommer WB. A novel analytical method for in vivo phosphate tracking. Febs Letters. 580: 5885-93. PMID 17034793 DOI: 10.1016/j.febslet.2006.09.048  1
2006 Lager I, Looger LL, Hilpert M, Lalonde S, Frommer WB. Conversion of a putative Agrobacterium sugar-binding protein into a FRET sensor with high selectivity for sucrose. The Journal of Biological Chemistry. 281: 30875-83. PMID 16912038 DOI: 10.1074/jbc.M605257200  1
2005 Deuschle K, Okumoto S, Fehr M, Looger LL, Kozhukh L, Frommer WB. Construction and optimization of a family of genetically encoded metabolite sensors by semirational protein engineering. Protein Science : a Publication of the Protein Society. 14: 2304-14. PMID 16131659 DOI: 10.1110/ps.051508105  1
2005 Looger LL, Lalonde S, Frommer WB. Genetically encoded FRET sensors for visualizing metabolites with subcellular resolution in living cells. Plant Physiology. 138: 555-7. PMID 15955913 DOI: 10.1104/pp.104.900151  1
2005 Okumoto S, Looger LL, Micheva KD, Reimer RJ, Smith SJ, Frommer WB. Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors. Proceedings of the National Academy of Sciences of the United States of America. 102: 8740-5. PMID 15939876 DOI: 10.1073/pnas.0503274102  1
2005 Deuschle K, Fehr M, Hilpert M, Lager I, Lalonde S, Looger LL, Okumoto S, Persson J, Schmidt A, Frommer WB. Genetically encoded sensors for metabolites. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 64: 3-9. PMID 15688353 DOI: 10.1002/cyto.a.20119  1
2005 Fehr M, Okumoto S, Deuschle K, Lager I, Looger LL, Persson J, Kozhukh L, Lalonde S, Frommer WB. Development and use of fluorescent nanosensors for metabolite imaging in living cells. Biochemical Society Transactions. 33: 287-90. PMID 15667328 DOI: 10.1042/BST0330287  1
2004 Dwyer MA, Looger LL, Hellinga HW. Computational design of a biologically active enzyme. Science (New York, N.Y.). 304: 1967-71. PMID 15218149 DOI: 10.1126/science.1098432  1
2004 Allert M, Rizk SS, Looger LL, Hellinga HW. Computational design of receptors for an organophosphate surrogate of the nerve agent soman. Proceedings of the National Academy of Sciences of the United States of America. 101: 7907-12. PMID 15148405 DOI: 10.1073/pnas.0401309101  1
2004 Okumoto S, Deuschle K, Fehr M, Hilpert M, Lager I, Lalonde S, Looger LL, Persson J, Schmidt A, Frommer WB. Genetically encoded sensors for ions and metabolites Soil Science and Plant Nutrition. 50: 947-953.  1
2003 Dwyer MA, Looger LL, Hellinga HW. Computational design of a Zn2+ receptor that controls bacterial gene expression. Proceedings of the National Academy of Sciences of the United States of America. 100: 11255-60. PMID 14500902 DOI: 10.1073/pnas.2032284100  1
2003 Looger LL, Dwyer MA, Smith JJ, Hellinga HW. Computational design of receptor and sensor proteins with novel functions. Nature. 423: 185-90. PMID 12736688 DOI: 10.1038/nature01556  1
2002 Liu H, Schmidt JJ, Bachand GD, Rizk SS, Looger LL, Hellinga HW, Montemagno CD. Control of a biomolecular motor-powered nanodevice with an engineered chemical switch. Nature Materials. 1: 173-7. PMID 12618806 DOI: 10.1038/nmat761  1
2002 de Lorimier RM, Smith JJ, Dwyer MA, Looger LL, Sali KM, Paavola CD, Rizk SS, Sadigov S, Conrad DW, Loew L, Hellinga HW. Construction of a fluorescent biosensor family. Protein Science : a Publication of the Protein Society. 11: 2655-75. PMID 12381848 DOI: 10.1110/ps.021860  1
2001 Looger LL, Hellinga HW. Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: implications for protein design and structural genomics. Journal of Molecular Biology. 307: 429-45. PMID 11243829 DOI: 10.1006/jmbi.2000.4424  1
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