| Year |
Citation |
Score |
| 2022 |
Zablon HA, VonHandorf A, Puga A. Mechanisms of chromate carcinogenesis by chromatin alterations. Advances in Pharmacology (San Diego, Calif.). 96: 1-23. PMID 36858770 DOI: 10.1016/bs.apha.2022.07.001 |
0.331 |
|
| 2022 |
Ko CI, Biesiada J, Zablon HA, Zhang X, Medvedovic M, Puga A. The aryl hydrocarbon receptor directs the differentiation of murine progenitor blastomeres. Cell Biology and Toxicology. PMID 36029422 DOI: 10.1007/s10565-022-09755-9 |
0.301 |
|
| 2021 |
VonHandorf A, Zablon HA, Puga A. Hexavalent chromium disrupts chromatin architecture. Seminars in Cancer Biology. PMID 34274487 DOI: 10.1016/j.semcancer.2021.07.009 |
0.36 |
|
| 2021 |
Zablon HA, Ko CI, Puga A. Converging Roles of the Aryl Hydrocarbon Receptor in Early Embryonic Development, Maintenance of Stemness and Tissue Repair. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 34009372 DOI: 10.1093/toxsci/kfab050 |
0.322 |
|
| 2020 |
VonHandorf A, Zablon HA, Biesiada J, Zhang X, Medvedovic M, Puga A. Hexavalent Chromium Promotes Differential Binding of CTCF to its Cognate Sites in Euchromatin. Epigenetics. PMID 33319643 DOI: 10.1080/15592294.2020.1864168 |
0.331 |
|
| 2020 |
Lee JE, Cho SG, Ko SG, Ahrmad SA, Puga A, Kim K. Regulation of a long noncoding RNA MALAT1 by aryl hydrocarbon receptor in pancreatic cancer cells and tissues. Biochemical and Biophysical Research Communications. PMID 32900487 DOI: 10.1016/J.Bbrc.2020.08.053 |
0.407 |
|
| 2019 |
Zablon HA, VonHandorf A, Puga A. Chromium exposure disrupts chromatin architecture upsetting the mechanisms that regulate transcription. Experimental Biology and Medicine (Maywood, N.J.). 1535370219839953. PMID 30935235 DOI: 10.1177/1535370219839953 |
0.398 |
|
| 2018 |
Hufgard JR, Sprowles JLN, Pitzer EM, Koch SE, Jiang M, Wang Q, Zhang X, Biesiada J, Rubinstein J, Puga A, Williams MT, Vorhees CV. Prenatal exposure to PCBs in Cyp1a2 knock-out mice interferes with F fertility, impairs long-term potentiation, reduces acoustic startle and impairs conditioned freezing contextual memory with minimal transgenerational effects. Journal of Applied Toxicology : Jat. PMID 30561030 DOI: 10.1002/Jat.3751 |
0.317 |
|
| 2018 |
VonHandorf A, Sánchez-Martín FJ, Biesiada J, Zhang H, Zhang X, Medvedovic M, Puga A. Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes. Epigenetics. 1-32. PMID 29561703 DOI: 10.1080/15592294.2018.1454243 |
0.429 |
|
| 2018 |
Barouki R, Melén E, Herceg Z, Beckers J, Chen J, Karagas M, Puga A, Xia Y, Chadwick L, Yan W, Audouze K, Slama R, Heindel J, Grandjean P, Kawamoto T, et al. Epigenetics as a mechanism linking developmental exposures to long-term toxicity. Environment International. 114: 77-86. PMID 29499450 DOI: 10.1016/J.Envint.2018.02.014 |
0.344 |
|
| 2017 |
Wang Q, Fan Y, Kurita H, Jiang M, Koch S, Rao MB, Rubinstein J, Puga A. Aryl Hydrocarbon Receptor Ablation in Cardiomyocytes Protects Male Mice from Heart Dysfunction Induced by NKX2.5 Haploinsufficiency. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28973413 DOI: 10.1093/Toxsci/Kfx164 |
0.363 |
|
| 2017 |
Ko CI, Puga A. Does the Aryl Hydrocarbon Receptor Regulate Pluripotency? Current Opinion in Toxicology. 2: 1-7. PMID 28920102 DOI: 10.1016/J.Cotox.2017.01.004 |
0.452 |
|
| 2017 |
Khanal T, Choi K, Leung YK, Wang J, Kim D, Janakiram V, Cho SG, Puga A, Ho SM, Kim K. Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer. Scientific Reports. 7: 10662. PMID 28878246 DOI: 10.1038/S41598-017-11106-2 |
0.384 |
|
| 2016 |
Abiko Y, Lin FY, Lee H, Puga A, Kumagai Y. Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator. The Journal of Toxicological Sciences. 41: 775-781. PMID 27853106 DOI: 10.2131/Jts.41.775 |
0.429 |
|
| 2016 |
Ko CI, Fan Y, de Gannes M, Wang Q, Xia Y, Puga A. Repression of the Aryl Hydrocarbon Receptor is Required to Maintain Mitotic Progression and Prevent Loss of Pluripotency of Embryonic Stem Cells. Stem Cells (Dayton, Ohio). PMID 27374890 DOI: 10.1002/Stem.2456 |
0.448 |
|
| 2016 |
Kurita H, Carreira VS, Fan Y, Jiang M, Naticchioni M, Koch S, Rubinstein J, Puga A. Ah Receptor Expression in Cardiomyocytes Protects Adult Female Mice from Heart Dysfunction Induced by TCDD Exposure. Toxicology. PMID 27163630 DOI: 10.1016/J.Tox.2016.05.006 |
0.388 |
|
| 2015 |
Wang Q, Kurita H, Carreira V, Ko CI, Fan Y, Zhang X, Biesiada J, Medvedovic M, Puga A. Ah Receptor Activation by Dioxin Disrupts Activin, BMP, and WNT Signals during the Early Differentiation of Mouse Embryonic Stem Cells and Inhibits Cardiomyocyte Functions. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26572662 DOI: 10.1093/Toxsci/Kfv246 |
0.451 |
|
| 2015 |
Abiko Y, Puga A, Kumagai Y. Covalent binding of quinones activates the Ah receptor in Hepa1c1c7 cells. The Journal of Toxicological Sciences. 40: 873-86. PMID 26558468 DOI: 10.2131/Jts.40.873 |
0.447 |
|
| 2015 |
Carreira VS, Fan Y, Kurita H, Wang Q, Ko CI, Naticchioni M, Jiang M, Koch S, Zhang X, Biesiada J, Medvedovic M, Xia Y, Rubinstein J, Puga A. Disruption of Ah Receptor Signaling during Mouse Development Leads to Abnormal Cardiac Structure and Function in the Adult. Plos One. 10: e0142440. PMID 26555816 DOI: 10.1371/Journal.Pone.0142440 |
0.314 |
|
| 2015 |
Grandjean P, Barouki R, Bellinger DC, Casteleyn L, Chadwick LH, Cordier S, Etzel RA, Gray KA, Ha EH, Junien C, Karagas M, Kawamoto T, Paige Lawrence B, Perera FP, Prins GS, ... Puga A, et al. Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives. Endocrinology. 156: 3408-15. PMID 26241067 DOI: 10.1210/En.2015-1350 |
0.319 |
|
| 2015 |
Carreira VS, Fan Y, Wang Q, Zhang X, Kurita H, Ko CI, Natichioni M, Jiang M, Koch S, Medvedovic M, Xia Y, Rubinstein J, Puga A. Ah receptor signaling controls the expression of cardiac development and homeostasis genes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26139165 DOI: 10.1093/Toxsci/Kfv138 |
0.367 |
|
| 2015 |
Li Y, Xie C, Murphy SK, Skaar D, Nye M, Vidal AC, Cecil KM, Dietrich KN, Puga A, Jirtle RL, Hoyo C. Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood. Environmental Health Perspectives. PMID 26115033 DOI: 10.1289/Ehp.1408577 |
0.345 |
|
| 2015 |
Mongan M, Meng Q, Wang J, Kao WW, Puga A, Xia Y. Gene-environment interactions target MAP3K1 signaling in eyelid morphogenesis. The Journal of Biological Chemistry. PMID 26109068 DOI: 10.1074/Jbc.M115.665729 |
0.411 |
|
| 2015 |
Sánchez-Martín FJ, Fan Y, Carreira V, Ovesen JL, Vonhandorf A, Xia Y, Puga A. Long-term Coexposure to Hexavalent Chromium and B[a]P Causes Tissue-Specific Differential Biological Effects in Liver and Gastrointestinal Tract of Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 146: 52-64. PMID 25820237 DOI: 10.1093/Toxsci/Kfv070 |
0.773 |
|
| 2015 |
Winans B, Nagari A, Chae M, Post CM, Ko CI, Puga A, Kraus WL, Lawrence BP. Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 194: 4446-57. PMID 25810390 DOI: 10.4049/Jimmunol.1402044 |
0.402 |
|
| 2015 |
Sánchez-Martín FJ, Lindquist DM, Landero-Figueroa J, Zhang X, Chen J, Cecil KM, Medvedovic M, Puga A. Sex- and tissue-specific methylome changes in brains of mice perinatally exposed to lead. Neurotoxicology. 46: 92-100. PMID 25530354 DOI: 10.1016/J.Neuro.2014.12.004 |
0.353 |
|
| 2015 |
Carreira V, Fan Y, Wang Q, Zhang X, Kurita H, Ko C, Natichioni M, Jiang M, Kock S, Medvedovic M, Rubinstein J, Puga A. The Ah receptor signaling pathway critically regulates cardiac development Toxicology Letters. 238: S278. DOI: 10.1016/J.Toxlet.2015.08.801 |
0.308 |
|
| 2014 |
Ovesen JL, Fan Y, Zhang X, Chen J, Medvedovic M, Xia Y, Puga A. Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) analysis uncovers broad changes in chromatin structure resulting from hexavalent chromium exposure. Plos One. 9: e97849. PMID 24837440 DOI: 10.1371/Journal.Pone.0097849 |
0.777 |
|
| 2014 |
Kurita H, Schnekenburger M, Ovesen JL, Xia Y, Puga A. The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 139: 121-32. PMID 24519526 DOI: 10.1093/Toxsci/Kfu027 |
0.787 |
|
| 2014 |
Ovesen JL, Fan Y, Chen J, Medvedovic M, Xia Y, Puga A. Long-term exposure to low-concentrations of Cr(VI) induce DNA damage and disrupt the transcriptional response to benzo[a]pyrene. Toxicology. 316: 14-24. PMID 24374135 DOI: 10.1016/J.Tox.2013.12.001 |
0.787 |
|
| 2014 |
Ko CI, Wang Q, Fan Y, Xia Y, Puga A. Pluripotency factors and Polycomb Group proteins repress aryl hydrocarbon receptor expression in murine embryonic stem cells. Stem Cell Research. 12: 296-308. PMID 24316986 DOI: 10.1016/J.Scr.2013.11.007 |
0.48 |
|
| 2013 |
Sánchez-Martín FJ, Fan Y, Lindquist DM, Xia Y, Puga A. Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells. Plos One. 8: e80558. PMID 24260418 DOI: 10.1371/Journal.Pone.0080558 |
0.372 |
|
| 2013 |
Wang Q, Chen J, Ko CI, Fan Y, Carreira V, Chen Y, Xia Y, Medvedovic M, Puga A. Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis. Environmental Health Perspectives. 121: 1334-43. PMID 24058054 DOI: 10.1289/Ehp.1307297 |
0.493 |
|
| 2012 |
Fan Y, Ovesen JL, Puga A. Long-term exposure to hexavalent chromium inhibits expression of tumor suppressor genes in cultured cells and in mice. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 26: 188-91. PMID 22613061 DOI: 10.1016/J.Jtemb.2012.04.009 |
0.782 |
|
| 2012 |
Wang J, Chen L, Ko CI, Zhang L, Puga A, Xia Y. Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiation. The Journal of Biological Chemistry. 287: 2787-97. PMID 22130668 DOI: 10.1074/Jbc.M111.281915 |
0.435 |
|
| 2011 |
Geh E, Meng Q, Mongan M, Wang J, Takatori A, Zheng Y, Puga A, Lang RA, Xia Y. Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closure. Proceedings of the National Academy of Sciences of the United States of America. 108: 17349-54. PMID 21969564 DOI: 10.1073/Pnas.1102297108 |
0.372 |
|
| 2011 |
Ovesen JL, Schnekenburger M, Puga A. Aryl hydrocarbon receptor ligands of widely different toxic equivalency factors induce similar histone marks in target gene chromatin. Toxicological Sciences : An Official Journal of the Society of Toxicology. 121: 123-31. PMID 21292640 DOI: 10.1093/Toxsci/Kfr032 |
0.78 |
|
| 2011 |
Puga A. Perspectives on the potential involvement of the AH receptor-dioxin axis in cardiovascular disease. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 256-61. PMID 21205634 DOI: 10.1093/Toxsci/Kfq393 |
0.46 |
|
| 2010 |
Reichard JF, Puga A. Effects of arsenic exposure on DNA methylation and epigenetic gene regulation. Epigenomics. 2: 87-104. PMID 20514360 DOI: 10.2217/Epi.09.45 |
0.418 |
|
| 2010 |
Peng Z, Geh E, Chen L, Meng Q, Fan Y, Sartor M, Shertzer HG, Liu ZG, Puga A, Xia Y. Inhibitor of kappaB kinase beta regulates redox homeostasis by controlling the constitutive levels of glutathione. Molecular Pharmacology. 77: 784-92. PMID 20159942 DOI: 10.1124/Mol.109.061424 |
0.419 |
|
| 2010 |
Wang Y, Fan Y, Puga A. Dioxin exposure disrupts the differentiation of mouse embryonic stem cells into cardiomyocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 225-37. PMID 20130022 DOI: 10.1093/Toxsci/Kfq038 |
0.479 |
|
| 2010 |
Fan Y, Boivin GP, Knudsen ES, Nebert DW, Xia Y, Puga A. The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Research. 70: 212-20. PMID 19996281 DOI: 10.1158/0008-5472.Can-09-3090 |
0.455 |
|
| 2009 |
Sartor MA, Schnekenburger M, Marlowe JL, Reichard JF, Wang Y, Fan Y, Ma C, Karyala S, Halbleib D, Liu X, Medvedovic M, Puga A. Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs. Environmental Health Perspectives. 117: 1139-46. PMID 19654925 DOI: 10.1289/Ehp.0800485 |
0.463 |
|
| 2009 |
Chen L, Ovesen JL, Puga A, Xia Y. Distinct contributions of JNK and p38 to chromium cytotoxicity and inhibition of murine embryonic stem cell differentiation. Environmental Health Perspectives. 117: 1124-30. PMID 19654923 DOI: 10.1289/Ehp.0800157 |
0.79 |
|
| 2009 |
Ma C, Marlowe JL, Puga A. The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways. Exs. 99: 231-57. PMID 19157064 DOI: 10.1007/978-3-7643-8336-7_9 |
0.353 |
|
| 2009 |
Matsumura F, Puga A, Tohyama C. Biological functions of the arylhydrocarbon receptor: beyond induction of cytochrome P450s. Introduction to this special issue. Biochemical Pharmacology. 77: 473. PMID 19041850 DOI: 10.1016/J.Bcp.2008.10.037 |
0.339 |
|
| 2009 |
Puga A, Ma C, Marlowe JL. The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways. Biochemical Pharmacology. 77: 713-22. PMID 18817753 DOI: 10.1016/J.Bcp.2008.08.031 |
0.482 |
|
| 2009 |
Gomez-Duran A, Carvajal-Gonzalez JM, Mulero-Navarro S, Santiago-Josefat B, Puga A, Fernandez-Salguero PM. Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling. Biochemical Pharmacology. 77: 700-12. PMID 18812170 DOI: 10.1016/J.Bcp.2008.08.032 |
0.454 |
|
| 2009 |
Kroening KK, Solivio MJV, García-López M, Puga A, Caruso JA. Cytotoxicity of arsenic-containing chemical warfare agent degradation products with metallomic approaches for metabolite analysis Metallomics. 1: 59-66. DOI: 10.1039/B816980B |
0.345 |
|
| 2008 |
Reichard JF, Sartor MA, Puga A. BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite. The Journal of Biological Chemistry. 283: 22363-70. PMID 18550526 DOI: 10.1074/Jbc.M801784200 |
0.446 |
|
| 2008 |
Marlowe JL, Fan Y, Chang X, Peng L, Knudsen ES, Xia Y, Puga A. The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis. Molecular Biology of the Cell. 19: 3263-71. PMID 18524851 DOI: 10.1091/Mbc.E08-04-0359 |
0.523 |
|
| 2008 |
Gomez-Duran A, Ballestar E, Carvajal-Gonzalez JM, Marlowe JL, Puga A, Esteller M, Fernandez-Salguero PM. Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse Ltbp-1 promoter regulates its constitutive expression in a dioxin receptor-dependent manner. Journal of Molecular Biology. 380: 1-16. PMID 18508077 DOI: 10.1016/J.Jmb.2008.04.056 |
0.476 |
|
| 2008 |
Peng L, Mayhew CN, Schnekenburger M, Knudsen ES, Puga A. Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors. Toxicology. 246: 242-7. PMID 18282651 DOI: 10.1016/J.Tox.2008.01.002 |
0.424 |
|
| 2007 |
Reichard JF, Motz GT, Puga A. Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1. Nucleic Acids Research. 35: 7074-86. PMID 17942419 DOI: 10.1093/Nar/Gkm638 |
0.397 |
|
| 2007 |
Schnekenburger M, Peng L, Puga A. HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation. Biochimica Et Biophysica Acta. 1769: 569-78. PMID 17707923 DOI: 10.1016/J.Bbaexp.2007.07.002 |
0.494 |
|
| 2007 |
Schnekenburger M, Talaska G, Puga A. Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. Molecular and Cellular Biology. 27: 7089-101. PMID 17682057 DOI: 10.1128/Mcb.00838-07 |
0.462 |
|
| 2007 |
Chang X, Fan Y, Karyala S, Schwemberger S, Tomlinson CR, Sartor MA, Puga A. Ligand-independent regulation of transforming growth factor beta1 expression and cell cycle progression by the aryl hydrocarbon receptor. Molecular and Cellular Biology. 27: 6127-39. PMID 17606626 DOI: 10.1128/Mcb.00323-07 |
0.431 |
|
| 2007 |
Reichard JF, Schnekenburger M, Puga A. Long term low-dose arsenic exposure induces loss of DNA methylation. Biochemical and Biophysical Research Communications. 352: 188-92. PMID 17107663 DOI: 10.1016/J.Bbrc.2006.11.001 |
0.357 |
|
| 2006 |
Talaska G, Ginsburg D, LaDow K, Puga A, Dalton T, Warshawsky D. Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies. Toxicology Letters. 162: 246-9. PMID 16256281 DOI: 10.1016/J.Toxlet.2005.09.020 |
0.331 |
|
| 2006 |
Singleton DW, Feng Y, Yang J, Puga A, Lee AV, Khan SA. Gene expression profiling reveals novel regulation by bisphenol-A in estrogen receptor-alpha-positive human cells. Environmental Research. 100: 86-92. PMID 16029874 DOI: 10.1016/J.Envres.2005.05.004 |
0.444 |
|
| 2005 |
Reichard JF, Dalton TP, Shertzer HG, Puga A. Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor. Dose-Response : a Publication of International Hormesis Society. 3: 306-31. PMID 18648615 DOI: 10.2203/Dose-Response.003.03.003 |
0.339 |
|
| 2005 |
Marlowe JL, Puga A. Aryl hydrocarbon receptor, cell cycle regulation, toxicity, and tumorigenesis. Journal of Cellular Biochemistry. 96: 1174-84. PMID 16211578 DOI: 10.1002/Jcb.20656 |
0.471 |
|
| 2005 |
Kann S, Estes C, Reichard JF, Huang MY, Sartor MA, Schwemberger S, Chen Y, Dalton TP, Shertzer HG, Xia Y, Puga A. Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status. Toxicological Sciences : An Official Journal of the Society of Toxicology. 87: 365-84. PMID 16014739 DOI: 10.1093/Toxsci/Kfi253 |
0.461 |
|
| 2005 |
Kann S, Huang MY, Estes C, Reichard JF, Sartor MA, Xia Y, Puga A. Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes. Molecular Pharmacology. 68: 336-46. PMID 15894712 DOI: 10.1124/Mol.105.011841 |
0.499 |
|
| 2005 |
Puga A, Tomlinson CR, Xia Y. Ah receptor signals cross-talk with multiple developmental pathways. Biochemical Pharmacology. 69: 199-207. PMID 15627472 DOI: 10.1016/J.Bcp.2004.06.043 |
0.447 |
|
| 2004 |
Puga A, Sartor MA, Huang MY, Kerzee JK, Wei YD, Tomlinson CR, Baxter CS, Medvedovic M. Gene expression profiles of mouse aorta and cultured vascular smooth muscle cells differ widely, yet show common responses to dioxin exposure. Cardiovascular Toxicology. 4: 385-404. PMID 15531781 DOI: 10.1385/Ct:4:4:385 |
0.45 |
|
| 2004 |
Barnes-Ellerbe S, Knudsen KE, Puga A. 2,3,7,8-Tetrachlorodibenzo-p-dioxin blocks androgen-dependent cell proliferation of LNCaP cells through modulation of pRB phosphorylation. Molecular Pharmacology. 66: 502-11. PMID 15322241 DOI: 10.1124/Mol.104.000356 |
0.694 |
|
| 2004 |
Tan Z, Huang M, Puga A, Xia Y. A critical role for MAP kinases in the control of Ah receptor complex activity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 82: 80-7. PMID 15272135 DOI: 10.1093/Toxsci/Kfh228 |
0.506 |
|
| 2004 |
Singleton DW, Feng Y, Chen Y, Busch SJ, Lee AV, Puga A, Khan SA. Bisphenol-A and estradiol exert novel gene regulation in human MCF-7 derived breast cancer cells. Molecular and Cellular Endocrinology. 221: 47-55. PMID 15223131 DOI: 10.1016/J.Mce.2004.04.010 |
0.439 |
|
| 2004 |
Marlowe JL, Knudsen ES, Schwemberger S, Puga A. The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phase-specific gene expression. The Journal of Biological Chemistry. 279: 29013-22. PMID 15123621 DOI: 10.1074/Jbc.M404315200 |
0.563 |
|
| 2004 |
Karyala S, Guo J, Sartor M, Medvedovic M, Kann S, Puga A, Ryan P, Tomlinson CR. Different global gene expression profiles in benzo[a]pyrene- and dioxin-treated vascular smooth muscle cells of AHR-knockout and wild-type mice. Cardiovascular Toxicology. 4: 47-73. PMID 15034205 DOI: 10.1385/Ct:4:1:47 |
0.438 |
|
| 2004 |
Guo J, Sartor M, Karyala S, Medvedovic M, Kann S, Puga A, Ryan P, Tomlinson CR. Expression of genes in the TGF-beta signaling pathway is significantly deregulated in smooth muscle cells from aorta of aryl hydrocarbon receptor knockout mice. Toxicology and Applied Pharmacology. 194: 79-89. PMID 14728982 DOI: 10.1016/J.Taap.2003.09.002 |
0.4 |
|
| 2004 |
Wei YD, Tepperman K, Huang MY, Sartor MA, Puga A. Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin. The Journal of Biological Chemistry. 279: 4110-9. PMID 14625279 DOI: 10.1074/Jbc.M310800200 |
0.533 |
|
| 2002 |
Puga A, Marlowe J, Barnes S, Chang CY, Maier A, Tan Z, Kerzee JK, Chang X, Strobeck M, Knudsen ES. Role of the aryl hydrocarbon receptor in cell cycle regulation. Toxicology. 181: 171-7. PMID 12505305 DOI: 10.1016/S0300-483X(02)00276-7 |
0.525 |
|
| 2002 |
Senft AP, Dalton TP, Nebert DW, Genter MB, Puga A, Hutchinson RJ, Kerzee JK, Uno S, Shertzer HG. Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor. Free Radical Biology & Medicine. 33: 1268-78. PMID 12398935 DOI: 10.1016/S0891-5849(02)01014-6 |
0.302 |
|
| 2002 |
Tan Z, Chang X, Puga A, Xia Y. Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function. Biochemical Pharmacology. 64: 771-80. PMID 12213569 DOI: 10.1016/S0006-2952(02)01138-3 |
0.525 |
|
| 2002 |
Puga A, Xia Y, Elferink C. Role of the aryl hydrocarbon receptor in cell cycle regulation. Chemico-Biological Interactions. 141: 117-30. PMID 12213388 DOI: 10.1016/S0009-2797(02)00069-8 |
0.439 |
|
| 2002 |
Dalton TP, Puga A, Shertzer HG. Induction of cellular oxidative stress by aryl hydrocarbon receptor activation. Chemico-Biological Interactions. 141: 77-95. PMID 12213386 DOI: 10.1016/S0009-2797(02)00067-4 |
0.359 |
|
| 2002 |
Maier A, Schumann BL, Chang X, Talaska G, Puga A. Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity. Mutation Research. 517: 101-11. PMID 12034312 DOI: 10.1016/S1383-5718(02)00057-8 |
0.42 |
|
| 2001 |
Dalton TP, Kerzee JK, Wang B, Miller M, Dieter MZ, Lorenz JN, Shertzer HG, Nerbert DW, Puga A. Dioxin exposure is an environmental risk factor for ischemic heart disease Cardiovascular Toxicology. 1: 285-298. PMID 12213967 DOI: 10.1385/Ct:1:4:285 |
0.319 |
|
| 2001 |
Borde-Chiché P, Diedericha M, Morceau F, Puga A, Wellman M, Dicato M. Regulation of transcription of the glutathione S-transferase P1 gene by methylation of the minimal promoter in human leukemia cells Biochemical Pharmacology. 61: 605-612. PMID 11239504 DOI: 10.1016/S0006-2952(00)00581-5 |
0.428 |
|
| 2000 |
Puga A, Maier A, Medvedovic M. The transcriptional signature of dioxin in human hepatoma HepG2 cells Biochemical Pharmacology. 60: 1129-1142. PMID 11007951 DOI: 10.1016/S0006-2952(00)00403-2 |
0.491 |
|
| 2000 |
Maier A, Dalton TP, Puga A. Disruption of dioxin-inducible phase I and phase II gene expression patterns by cadmium, chromium, and arsenic Molecular Carcinogenesis. 28: 225-235. PMID 10972992 DOI: 10.1002/1098-2744(200008)28:4<225::Aid-Mc5>3.0.Co;2-O |
0.484 |
|
| 2000 |
Strobeck MW, Fribourg AF, Puga A, Knudsen ES. Restoration of retinoblastoma mediated signaling to Cdk2 results in cell cycle arrest Oncogene. 19: 1857-1867. PMID 10773875 DOI: 10.1038/Sj.Onc.1203510 |
0.431 |
|
| 2000 |
Puga A, Barnes SJ, Chang C, Zhu H, Nephew KP, Khan SA, Shertzer HG. Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochemical Pharmacology. 59: 997-1005. PMID 10692565 DOI: 10.1016/S0006-2952(99)00406-2 |
0.449 |
|
| 2000 |
Puga A, Barnes SJ, Dalton TP, Chang Cy, Knudsen ES, Maier MA. Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. The Journal of Biological Chemistry. 275: 2943-50. PMID 10644764 DOI: 10.1074/Jbc.275.4.2943 |
0.669 |
|
| 1999 |
Shertzer HG, Puga A, Chang CY, Smith P, Nebert DW, Setchell KDR, Dalton TP. Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones Chemico-Biological Interactions. 123: 31-49. PMID 10597900 DOI: 10.1016/S0009-2797(99)00121-0 |
0.371 |
|
| 1999 |
Vasiliou V, Reuter SF, Williams S, Puga A, Nebert DW. Mouse cytosolic class 3 aldehyde dehydrogenase (Aldh3a1): Gene structure and regulation of constitutive and dioxin-inducible expression Pharmacogenetics. 9: 569-580. PMID 10591537 DOI: 10.1097/00008571-199910000-00004 |
0.459 |
|
| 1999 |
Carvan MJ, Ponomareva LV, Solis WA, Matlib RS, Puga A, Nebert DW. Trout CYP1A3 Gene: Recognition of Fish DNA Motifs by Mouse Regulatory Proteins. Marine Biotechnology (New York, N.Y.). 1: 155-166. PMID 10373624 DOI: 10.1007/Pl00011763 |
0.465 |
|
| 1999 |
Dalton TP, Shertzer HG, Puga A. Regulation of gene expression by reactive oxygen Annual Review of Pharmacology and Toxicology. 39: 67-101. PMID 10331077 DOI: 10.1146/Annurev.Pharmtox.39.1.67 |
0.376 |
|
| 1999 |
Carvan MJ, Ponomareva LV, Solis WA, Matlib RS, Puga A, Nebert DW. Trout CYP1A3 gene: Recognition of fish DNA motifs by mouse regulatory proteins Marine Biotechnology. 1: 155-166. |
0.362 |
|
| 1998 |
Shertzer HG, Nebert DW, Puga A, Ary M, Sonntag D, Dixon K, Robinson LJ, Cianciolo E, Dalton TP. Dioxin causes a sustained oxidative stress response in the mouse Biochemical and Biophysical Research Communications. 253: 44-48. PMID 9875217 DOI: 10.1006/Bbrc.1998.9753 |
0.321 |
|
| 1998 |
Fitzgerald CT, Nebert DW, Puga A. Regulation of mouse Ah receptor (Ahr) gene basal expression by members of the Sp family of transcription factors Dna and Cell Biology. 17: 811-822. PMID 9778040 DOI: 10.1089/Dna.1998.17.811 |
0.353 |
|
| 1998 |
Chang CY, Puga A. Constitutive activation of the aromatic hydrocarbon receptor Molecular and Cellular Biology. 18: 525-535. PMID 9418899 DOI: 10.1128/Mcb.18.1.525 |
0.513 |
|
| 1997 |
Puga A, Hoffer A, Zhou S, Bohm JM, Leikauf GD, Shertzer HG. Sustained increase in intracellular free calcium and activation of cyclooxygenase-2 expression in mouse hepatoma cells treated with dioxin Biochemical Pharmacology. 54: 1287-1296. PMID 9393671 DOI: 10.1016/S0006-2952(97)00417-6 |
0.403 |
|
| 1997 |
Micka J, Milatovich A, Menon A, Grabowski GA, Puga A, Nebert DW. Human Ah receptor (AHR) gene: Localization to 7p15 and suggestive correlation of polymorphism with CYP1A1 inducibility Pharmacogenetics. 7: 95-101. PMID 9170146 DOI: 10.1097/00008571-199704000-00002 |
0.47 |
|
| 1996 |
Hoffer A, Chang CY, Puga A. Dioxin induces transcription of fos and jun genes by Ah receptor-dependent and -independent pathways Toxicology and Applied Pharmacology. 141: 238-247. PMID 8917696 DOI: 10.1016/S0041-008X(96)80029-9 |
0.506 |
|
| 1996 |
FitzGerald CT, Fernandez-Salguero P, Gonzalez FJ, Nebert DW, Puga A. Differential regulation of mouse Ah receptor gene expression in cell lines of different tissue origins Archives of Biochemistry and Biophysics. 333: 170-178. PMID 8806768 DOI: 10.1006/Abbi.1996.0378 |
0.474 |
|
| 1996 |
Puga A, Micka J, Chang CY, Liang HC, Nebert DW. Role of molecular biology in risk assessment Advances in Experimental Medicine and Biology. 387: 395-404. PMID 8794234 DOI: 10.1007/978-1-4757-9480-9_48 |
0.302 |
|
| 1996 |
Liang HCL, Li H, Mckinnon RA, Duffy JJ, Potter SS, Puga A, Nebert DW. Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism Proceedings of the National Academy of Sciences of the United States of America. 93: 1671-1676. PMID 8643688 DOI: 10.1073/Pnas.93.4.1671 |
0.345 |
|
| 1996 |
Nebert DW, McKinnon RA, Puga A. Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer Dna and Cell Biology. 15: 273-280. PMID 8639263 DOI: 10.1089/Dna.1996.15.273 |
0.367 |
|
| 1995 |
Vasiliou V, Puga A, Chang CY, Tabor MW, Nebert DW. Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression Biochemical Pharmacology. 50: 2057-2068. PMID 8849333 DOI: 10.1016/0006-2952(95)02108-6 |
0.425 |
|
| 1995 |
Duh JL, Zhu H, Shertzer HG, Nebert DW, Puga A. The Y-box motif mediates redox-dependent transcriptional activation in mouse cells Journal of Biological Chemistry. 270: 30499-30507. PMID 8530481 DOI: 10.1074/Jbc.270.51.30499 |
0.443 |
|
| 1995 |
Yao Y, Hoffer A, Chang -y. C, Puga A. Dioxin activates HIV-1 gene expression by an oxidative stress pathway requiring a functional cytochrome P450 CYP1A1 enzyme Environmental Health Perspectives. 103: 366-371. PMID 7607137 DOI: 10.1289/Ehp.95103366 |
0.448 |
|
| 1994 |
Vasunia KB, Miller ML, Puga A, Baxter CS. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is expressed in mouse skin in response to tumor-promoting agents and modulates dermal inflammation and epidermal dark cell numbers. Carcinogenesis. 15: 653-60. PMID 8149476 DOI: 10.1093/Carcin/15.4.653 |
0.339 |
|
| 1994 |
Carrier F, Chang CY, Duh JL, Nebert DW, Puga A. Interaction of the regulatory domains of the murine Cyp1a1 gene with two DNA-binding proteins in addition to the Ah receptor and the Ah receptor nuclear translocator (ARNT) Biochemical Pharmacology. 48: 1767-1778. PMID 7980646 DOI: 10.1016/0006-2952(94)90463-4 |
0.465 |
|
| 1994 |
Liu RM, Vasiliou V, Zhu H, Duh JL, Tabor MW, Puga A, Nebert DW, Sainsbury M, Shertzer HG. Regulation of [ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[l,2-b]indole in mouse hepatoma cell lines Carcinogenesis. 15: 2347-2352. PMID 7955076 DOI: 10.1093/Carcin/15.10.2347 |
0.428 |
|
| 1994 |
Vasiliou V, Theurer MJ, Puga A, Reuter SF, Nebert DW. Mouse dioxin-inducible NAD(P)H: Menadione oxidoreductase: NMO1 cDNA sequence and genetic differences in mRNA levels Pharmacogenetics. 4: 341-348. PMID 7704040 DOI: 10.1097/00008571-199412000-00007 |
0.431 |
|
| 1993 |
Vasiliou V, Puga A, Nebert DW. Mouse class 3 aldehyde dehydrogenases: Positive and negative regulation of gene expression Advances in Experimental Medicine and Biology. 328: 131-140. PMID 8493891 DOI: 10.1007/978-1-4615-2904-0_15 |
0.347 |
|
| 1993 |
Nebert DW, Puga A, Vasiliou V. Roel of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction Annals of the New York Academy of Sciences. 685: 624-640. PMID 8395783 DOI: 10.1111/J.1749-6632.1993.Tb35928.X |
0.482 |
|
| 1993 |
Pilon AL, Kozak CA, Nebert DW, Puga A. Localization of the murine Hmg1 gene, encoding an HMG-box protein, to mouse Chromosome 2 Mammalian Genome. 4: 612-614. PMID 8268661 DOI: 10.1007/Bf00361395 |
0.346 |
|
| 1993 |
Diederich M, Wellman M, Visvikis A, Puga A, Siest G. The 5' untranslated region of the human γ-glutamyl transferase mRNA contains a tissue-specific active translational enhancer Febs Letters. 332: 88-92. PMID 8104826 DOI: 10.1016/0014-5793(93)80490-L |
0.346 |
|
| 1992 |
Puga A, Nebert DW, Carrier F. Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1 Dna and Cell Biology. 11: 269-281. PMID 1605850 DOI: 10.1089/Dna.1992.11.269 |
0.428 |
|
| 1992 |
Vasiliou V, Puga A, Nebert DW. Negative regulation of the murine cytosolic aldehyde dehydrogenase-3 (Aldh-3c) gene by functional CYP1A1 and CYP1A2 proteins Biochemical and Biophysical Research Communications. 187: 413-419. PMID 1520328 DOI: 10.1016/S0006-291X(05)81508-6 |
0.437 |
|
| 1992 |
Carrier F, Owens RA, Nebert DW, Puga A. Dioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylation. Molecular and Cellular Biology. 12: 1856-63. PMID 1312672 DOI: 10.1128/Mcb.12.4.1856 |
0.485 |
|
| 1992 |
Puga A, Raychaudhuri B, Nebert DW. Transcriptional derepression of the murine Cyp1a-1 gene by mevinolin Faseb Journal. 6: 777-785. PMID 1311272 DOI: 10.1096/Fasebj.6.2.1311272 |
0.494 |
|
| 1991 |
Nebert DW, Petersen DD, Puga A. Human AH locus polymorphism and cancer inducibility of CYP1A1 and other genes by combustion products and dioxin Pharmacogenetics. 1: 68-78. PMID 1844873 DOI: 10.1097/00008571-199111000-00003 |
0.439 |
|
| 1990 |
Puga A, Raychaudhuri B, Salata K, Zhang YH, Nebert DW. Stable expression of mouse Cyp1a1 and human CYP1A2 cDNAs transfected into mouse hepatoma cells lacking detectable P450 enzyme activity Dna and Cell Biology. 9: 425-436. PMID 2206399 DOI: 10.1089/Dna.1990.9.425 |
0.436 |
|
| 1990 |
Puga A, Nebert DW. Evolution of the P450 gene superfamily and regulation of the murine Cyp1a1 gene Biochemical Society Transactions. 18: 7-10. PMID 2185093 DOI: 10.1042/Bst0180007 |
0.371 |
|
| 1990 |
RayChaudhuri B, Nebert DW, Puga A. The murine Cyp1a-1 gene negatively regulates its own transcription and that of other members of the aromatic hydrocarbon-responsive [Ah] gene battery Molecular Endocrinology. 4: 1773-1781. PMID 2082180 DOI: 10.1210/Mend-4-12-1773 |
0.469 |
|
| 1989 |
Shibata M, Puga A, Salata KF, Bachurski CJ, Lerman MI, Notkins AL. Expression of a viral gene in insulin-producing cell lines renders them susceptible to immunological destruction. Diabetologia. 32: 709-15. PMID 2556307 DOI: 10.1007/Bf00274529 |
0.375 |
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