Gideon Dreyfuss - Publications

Biochemistry and Biophysics University of Pennsylvania, Philadelphia, PA, United States 
Spinal Muscular Atrophy, RNA binding proteins, Splicing, High-Throughput Screening

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Venters CC, Oh JM, Di C, So BR, Dreyfuss G. U1 snRNP Telescripting: Suppression of Premature Transcription Termination in Introns as a New Layer of Gene Regulation. Cold Spring Harbor Perspectives in Biology. 11. PMID 30709878 DOI: 10.1101/cshperspect.a032235  0.32
2017 Wan L, Dreyfuss G. Splicing-Correcting Therapy for SMA. Cell. 170: 5. PMID 28666123 DOI: 10.1016/j.cell.2017.06.028  1
2016 So BR, Wan L, Zhang Z, Li P, Babiash E, Duan J, Younis I, Dreyfuss G. A U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange. Nature Structural & Molecular Biology. PMID 26828962 DOI: 10.1038/nsmb.3167  1
2015 Dreyfuss G. On the occasion of the 20th anniversary of the RNA journal. Rna (New York, N.Y.). 21: 603-4. PMID 25780157 DOI: 10.1261/rna.050690.115  1
2013 Zhang Z, Pinto AM, Wan L, Wang W, Berg MG, Oliva I, Singh LN, Dengler C, Wei Z, Dreyfuss G. Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: 19348-53. PMID 24191055 DOI: 10.1073/pnas.1319280110  1
2013 Younis I, Dittmar K, Wang W, Foley SW, Berg MG, Hu KY, Wei Z, Wan L, Dreyfuss G. Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA. Elife. 2: e00780. PMID 23908766 DOI: 10.7554/eLife.00780  1
2013 Liu X, Biswas S, Berg MG, Antapli CM, Xie F, Wang Q, Tang MC, Tang GL, Zhang L, Dreyfuss G, Cheng YQ. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. Journal of Natural Products. 76: 685-93. PMID 23517093 DOI: 10.1021/np300913h  1
2012 Berg MG, Singh LN, Younis I, Liu Q, Pinto AM, Kaida D, Zhang Z, Cho S, Sherrill-Mix S, Wan L, Dreyfuss G. U1 snRNP determines mRNA length and regulates isoform expression. Cell. 150: 53-64. PMID 22770214 DOI: 10.1016/j.cell.2012.05.029  1
2012 Berg MG, Wan L, Younis I, Diem MD, Soo M, Wang C, Dreyfuss G. A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis. Molecular and Cellular Biology. 32: 1271-83. PMID 22252314 DOI: 10.1128/MCB.05788-11  1
2012 Gruber JJ, Olejniczak SH, Yong J, La Rocca G, Dreyfuss G, Thompson CB. Ars2 promotes proper replication-dependent histone mRNA 3' end formation. Molecular Cell. 45: 87-98. PMID 22244333 DOI: 10.1016/j.molcel.2011.12.020  1
2011 Kataoka N, Diem MD, Yoshida M, Hatai C, Dobashi I, Dreyfuss G, Hagiwara M, Ohno M. Specific Y14 domains mediate its nucleo-cytoplasmic shuttling and association with spliced mRNA. Scientific Reports. 1: 92. PMID 22355610 DOI: 10.1038/srep00092  1
2011 Zhang R, So BR, Li P, Yong J, Glisovic T, Wan L, Dreyfuss G. Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly. Cell. 146: 384-95. PMID 21816274 DOI: 10.1016/j.cell.2011.06.043  1
2010 Kaida D, Berg MG, Younis I, Kasim M, Singh LN, Wan L, Dreyfuss G. U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation. Nature. 468: 664-8. PMID 20881964 DOI: 10.1038/nature09479  1
2010 Yong J, Kasim M, Bachorik JL, Wan L, Dreyfuss G. Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis. Molecular Cell. 38: 551-62. PMID 20513430 DOI: 10.1016/j.molcel.2010.03.014  1
2010 Mei Y, Yong J, Liu H, Shi Y, Meinkoth J, Dreyfuss G, Yang X. tRNA binds to cytochrome c and inhibits caspase activation. Molecular Cell. 37: 668-78. PMID 20227371 DOI: 10.1016/j.molcel.2010.01.023  1
2010 Cho S, Dreyfuss G. A degron created by SMN2 exon 7 skipping is a principal contributor to spinal muscular atrophy severity. Genes & Development. 24: 438-42. PMID 20194437 DOI: 10.1101/gad.1884910  1
2010 Younis I, Berg M, Kaida D, Dittmar K, Wang C, Dreyfuss G. Rapid-response splicing reporter screens identify differential regulators of constitutive and alternative splicing. Molecular and Cellular Biology. 30: 1718-28. PMID 20123975 DOI: 10.1128/MCB.01301-09  1
2009 Gruber JJ, Zatechka DS, Sabin LR, Yong J, Lum JJ, Kong M, Zong WX, Zhang Z, Lau CK, Rawlings J, Cherry S, Ihle JN, Dreyfuss G, Thompson CB. Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell. 138: 328-39. PMID 19632182 DOI: 10.1016/j.cell.2009.04.046  1
2009 Lau CK, Bachorik JL, Dreyfuss G. Gemin5-snRNA interaction reveals an RNA binding function for WD repeat domains. Nature Structural & Molecular Biology. 16: 486-91. PMID 19377484 DOI: 10.1038/nsmb.1584  1
2009 Cooper TA, Wan L, Dreyfuss G. RNA and disease. Cell. 136: 777-93. PMID 19239895 DOI: 10.1016/j.cell.2009.02.011  1
2008 Kataoka N, Dreyfuss G. Preparation of efficient splicing extracts from whole cells, nuclei, and cytoplasmic fractions. Methods in Molecular Biology (Clifton, N.J.). 488: 357-65. PMID 18982302 DOI: 10.1007/978-1-60327-475-3_23  1
2008 Wan L, Ottinger E, Cho S, Dreyfuss G. Inactivation of the SMN complex by oxidative stress. Molecular Cell. 31: 244-54. PMID 18657506 DOI: 10.1016/j.molcel.2008.06.004  1
2008 Steitz JA, Dreyfuss G, Krainer AR, Lamond AI, Matera AG, Padgett RA. Where in the cell is the minor spliceosome? Proceedings of the National Academy of Sciences of the United States of America. 105: 8485-6. PMID 18562285 DOI: 10.1073/pnas.0804024105  1
2008 Zhang Z, Lotti F, Dittmar K, Younis I, Wan L, Kasim M, Dreyfuss G. SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing. Cell. 133: 585-600. PMID 18485868 DOI: 10.1016/j.cell.2008.03.031  1
2008 Glisovic T, Bachorik JL, Yong J, Dreyfuss G. RNA-binding proteins and post-transcriptional gene regulation. Febs Letters. 582: 1977-86. PMID 18342629 DOI: 10.1016/j.febslet.2008.03.004  1
2008 Vignoles P, Rondelaud D, Dreyfuss G. Paramphistomum daubneyi: production dynamics and infectivity of metacercariae originating from snails dissected at regular intervals. Journal of Helminthology. 82: 175-80. PMID 18328114 DOI: 10.1017/S0022149X0893652X  0.01
2007 Diem MD, Chan CC, Younis I, Dreyfuss G. PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs. Nature Structural & Molecular Biology. 14: 1173-9. PMID 18026120 DOI: 10.1038/nsmb1321  1
2007 Kolb SJ, Battle DJ, Dreyfuss G. Molecular functions of the SMN complex. Journal of Child Neurology. 22: 990-4. PMID 17761654 DOI: 10.1177/0883073807305666  1
2007 Battle DJ, Kasim M, Wang J, Dreyfuss G. SMN-independent subunits of the SMN complex. Identification of a small nuclear ribonucleoprotein assembly intermediate. The Journal of Biological Chemistry. 282: 27953-9. PMID 17640873 DOI: 10.1074/jbc.M702317200  1
2007 Kim EK, Noh KT, Yoon JH, Cho JH, Yoon KW, Dreyfuss G, Choi EJ. Positive regulation of ASK1-mediated c-Jun NH(2)-terminal kinase signaling pathway by the WD-repeat protein Gemin5. Cell Death and Differentiation. 14: 1518-28. PMID 17541429 DOI: 10.1038/sj.cdd.4402157  1
2007 Neumann M, Igaz LM, Kwong LK, Nakashima-Yasuda H, Kolb SJ, Dreyfuss G, Kretzschmar HA, Trojanowski JQ, Lee VM. Absence of heterogeneous nuclear ribonucleoproteins and survival motor neuron protein in TDP-43 positive inclusions in frontotemporal lobar degeneration. Acta Neuropathologica. 113: 543-8. PMID 17415574 DOI: 10.1007/s00401-007-0221-x  1
2006 Battle DJ, Kasim M, Yong J, Lotti F, Lau CK, Mouaikel J, Zhang Z, Han K, Wan L, Dreyfuss G. The SMN complex: an assembly machine for RNPs. Cold Spring Harbor Symposia On Quantitative Biology. 71: 313-20. PMID 17381311 DOI: 10.1101/sqb.2006.71.001  1
2006 Battle DJ, Lau CK, Wan L, Deng H, Lotti F, Dreyfuss G. The Gemin5 protein of the SMN complex identifies snRNAs. Molecular Cell. 23: 273-9. PMID 16857593 DOI: 10.1016/j.molcel.2006.05.036  1
2006 Sumner CJ, Kolb SJ, Harmison GG, Jeffries NO, Schadt K, Finkel RS, Dreyfuss G, Fischbeck KH. SMN mRNA and protein levels in peripheral blood: biomarkers for SMA clinical trials. Neurology. 66: 1067-73. PMID 16481599 DOI: 10.1212/01.wnl.0000201929.56928.13  1
2006 Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S. Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes & Development. 20: 355-67. PMID 16452507 DOI: 10.1101/gad.1389006  1
2006 Kolb SJ, Gubitz AK, Olszewski RF, Ottinger E, Sumner CJ, Fischbeck KH, Dreyfuss G. A novel cell immunoassay to measure survival of motor neurons protein in blood cells. Bmc Neurology. 6: 6. PMID 16451734 DOI: 10.1186/1471-2377-6-6  1
2005 Golembe TJ, Yong J, Dreyfuss G. Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPs. Molecular and Cellular Biology. 25: 10989-1004. PMID 16314521 DOI: 10.1128/MCB.25.24.10989-11004.2005  1
2005 Wan L, Battle DJ, Yong J, Gubitz AK, Kolb SJ, Wang J, Dreyfuss G. The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy. Molecular and Cellular Biology. 25: 5543-51. PMID 15964810 DOI: 10.1128/MCB.25.13.5543-5551.2005  1
2005 Ma Y, Dostie J, Dreyfuss G, Van Duyne GD. The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure. Structure (London, England : 1993). 13: 883-92. PMID 15939020 DOI: 10.1016/j.str.2005.03.014  1
2005 Feng W, Gubitz AK, Wan L, Battle DJ, Dostie J, Golembe TJ, Dreyfuss G. Gemins modulate the expression and activity of the SMN complex. Human Molecular Genetics. 14: 1605-11. PMID 15843395 DOI: 10.1093/hmg/ddi168  1
2005 Rondelaud D, Hourdin P, Vignoles P, Dreyfuss G. The contamination of wild watercress with Fasciola hepatica in central France depends on the ability of several lymnaeid snails to migrate upstream towards the beds. Parasitology Research. 95: 305-9. PMID 15682339 DOI: 10.1007/s00436-004-1283-5  0.01
2005 Golembe TJ, Yong J, Battle DJ, Feng W, Wan L, Dreyfuss G. Lymphotropic Herpesvirus saimiri uses the SMN complex to assemble Sm cores on its small RNAs. Molecular and Cellular Biology. 25: 602-11. PMID 15632062 DOI: 10.1128/MCB.25.2.602-611.2005  1
2004 Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes? Trends in Cell Biology. 14: 226-32. PMID 15130578 DOI: 10.1016/j.tcb.2004.03.010  1
2004 Gubitz AK, Feng W, Dreyfuss G. The SMN complex. Experimental Cell Research. 296: 51-6. PMID 15120993 DOI: 10.1016/j.yexcr.2004.03.022  1
2004 Yong J, Golembe TJ, Battle DJ, Pellizzoni L, Dreyfuss G. snRNAs contain specific SMN-binding domains that are essential for snRNP assembly. Molecular and Cellular Biology. 24: 2747-56. PMID 15024064 DOI: 10.1128/MCB.24.7.2747-2756.2004  1
2004 Chan CC, Dostie J, Diem MD, Feng W, Mann M, Rappsilber J, Dreyfuss G. eIF4A3 is a novel component of the exon junction complex. Rna (New York, N.Y.). 10: 200-9. PMID 14730019 DOI: 10.1261/rna.5230104  1
2004 Kawano T, Kataoka N, Dreyfuss G, Sakamoto H. Ce-Y14 and MAG-1, components of the exon-exon junction complex, are required for embryogenesis and germline sexual switching in Caenorhabditis elegans. Mechanisms of Development. 121: 27-35. PMID 14706697 DOI: 10.1016/j.mod.2003.11.003  1
2004 Kataoka N, Dreyfuss G. A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex. The Journal of Biological Chemistry. 279: 7009-13. PMID 14625303 DOI: 10.1074/jbc.M307692200  1
2003 Rappsilber J, Friesen WJ, Paushkin S, Dreyfuss G, Mann M. Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode. Analytical Chemistry. 75: 3107-14. PMID 12964758 DOI: 10.1021/ac026283q  1
2003 Lau CK, Diem MD, Dreyfuss G, Van Duyne GD. Structure of the Y14-Magoh core of the exon junction complex. Current Biology : Cb. 13: 933-41. PMID 12781131 DOI: 10.1016/S0960-9822(03)00328-2  1
2003 Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T. A uniform system for microRNA annotation. Rna (New York, N.Y.). 9: 277-9. PMID 12592000 DOI: 10.1261/rna.2183803  1
2003 Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G. Numerous microRNPs in neuronal cells containing novel microRNAs. Rna (New York, N.Y.). 9: 180-6. PMID 12554860 DOI: 10.1261/rna.2141503  1
2002 Pellizzoni L, Yong J, Dreyfuss G. Essential role for the SMN complex in the specificity of snRNP assembly. Science (New York, N.Y.). 298: 1775-9. PMID 12459587 DOI: 10.1126/science.1074962  1
2002 Massenet S, Pellizzoni L, Paushkin S, Mattaj IW, Dreyfuss G. The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway. Molecular and Cellular Biology. 22: 6533-41. PMID 12192051 DOI: 10.1128/MCB.22.18.6533-6541.2002  1
2002 Dostie J, Dreyfuss G. Translation is required to remove Y14 from mRNAs in the cytoplasm. Current Biology : Cb. 12: 1060-7. PMID 12121612 DOI: 10.1016/S0960-9822(02)00902-8  1
2002 Paushkin S, Gubitz AK, Massenet S, Dreyfuss G. The SMN complex, an assemblyosome of ribonucleoproteins. Current Opinion in Cell Biology. 14: 305-12. PMID 12067652 DOI: 10.1016/S0955-0674(02)00332-0  1
2002 Baccon J, Pellizzoni L, Rappsilber J, Mann M, Dreyfuss G. Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. The Journal of Biological Chemistry. 277: 31957-62. PMID 12065586 DOI: 10.1074/jbc.M203478200  1
2002 Rondelaud D, Vignoles P, Dreyfuss G. The presence of predators modifies the larval development of Fasciola hepatica in surviving Lymnaea truncatula. Journal of Helminthology. 76: 175-8. PMID 12015831 DOI: 10.1079/JOH2001103  0.01
2002 Dreyfuss G, Kim VN, Kataoka N. Messenger-RNA-binding proteins and the messages they carry. Nature Reviews. Molecular Cell Biology. 3: 195-205. PMID 11994740 DOI: 10.1038/nrm760  1
2002 Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, Rappsilber J, Mann M, Dreyfuss G. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes & Development. 16: 720-8. PMID 11914277 DOI: 10.1101/gad.974702  1
2002 Yong J, Pellizzoni L, Dreyfuss G. Sequence-specific interaction of U1 snRNA with the SMN complex. The Embo Journal. 21: 1188-96. PMID 11867547 DOI: 10.1093/emboj/21.5.1188  1
2002 Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G. A novel WD repeat protein component of the methylosome binds Sm proteins. The Journal of Biological Chemistry. 277: 8243-7. PMID 11756452 DOI: 10.1074/jbc.M109984200  1
2002 Pellizzoni L, Baccon J, Rappsilber J, Mann M, Dreyfuss G. Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. The Journal of Biological Chemistry. 277: 7540-5. PMID 11748230 DOI: 10.1074/jbc.M110141200  1
2002 Gubitz AK, Mourelatos Z, Abel L, Rappsilber J, Mann M, Dreyfuss G. Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. The Journal of Biological Chemistry. 277: 5631-6. PMID 11714716 DOI: 10.1074/jbc.M109448200  1
2001 Friesen WJ, Paushkin S, Wyce A, Massenet S, Pesiridis GS, Van Duyne G, Rappsilber J, Mann M, Dreyfuss G. The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins. Molecular and Cellular Biology. 21: 8289-300. PMID 11713266 DOI: 10.1128/MCB.21.24.8289-8300.2001  1
2001 Kataoka N, Diem MD, Kim VN, Yong J, Dreyfuss G. Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex. The Embo Journal. 20: 6424-33. PMID 11707413 DOI: 10.1093/emboj/20.22.6424  1
2001 Mourelatos Z, Abel L, Yong J, Kataoka N, Dreyfuss G. SMN interacts with a novel family of hnRNP and spliceosomal proteins. The Embo Journal. 20: 5443-52. PMID 11574476 DOI: 10.1093/emboj/20.19.5443  1
2001 Wang J, Dreyfuss G. Characterization of functional domains of the SMN protein in vivo. The Journal of Biological Chemistry. 276: 45387-93. PMID 11572858 DOI: 10.1074/jbc.M105059200  1
2001 Kim VN, Dreyfuss G. Nuclear mRNA binding proteins couple pre-mRNA splicing and post-splicing events. Molecules and Cells. 12: 1-10. PMID 11561715  1
2001 Kim VN, Kataoka N, Dreyfuss G. Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex. Science (New York, N.Y.). 293: 1832-6. PMID 11546873 DOI: 10.1126/science.1062829  1
2001 Pellizzoni L, Baccon J, Charroux B, Dreyfuss G. The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1. Current Biology : Cb. 11: 1079-88. PMID 11509230 DOI: 10.1016/S0960-9822(01)00316-5  1
2001 Friesen WJ, Massenet S, Paushkin S, Wyce A, Dreyfuss G. SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets. Molecular Cell. 7: 1111-7. PMID 11389857 DOI: 10.1016/S1097-2765(01)00244-1  1
2001 Kim VN, Yong J, Kataoka N, Abel L, Diem MD, Dreyfuss G. The Y14 protein communicates to the cytoplasm the position of exon-exon junctions. The Embo Journal. 20: 2062-8. PMID 11296238 DOI: 10.1093/emboj/20.8.2062  1
2001 Pellizzoni L, Charroux B, Rappsilber J, Mann M, Dreyfuss G. A functional interaction between the survival motor neuron complex and RNA polymerase II. The Journal of Cell Biology. 152: 75-85. PMID 11149922 DOI: 10.1083/jcb.152.1.75  1
2001 Wang J, Dreyfuss G. A cell system with targeted disruption of the SMN gene: functional conservation of the SMN protein and dependence of Gemin2 on SMN. The Journal of Biological Chemistry. 276: 9599-605. PMID 11121410 DOI: 10.1074/jbc.M009162200  1
2001 Wan L, Kim JK, Pollard VW, Dreyfuss G. Mutational definition of RNA-binding and protein-protein interaction domains of heterogeneous nuclear RNP C1. The Journal of Biological Chemistry. 276: 7681-8. PMID 11113151 DOI: 10.1074/jbc.M010207200  1
2000 Wan L, Dockendorff TC, Jongens TA, Dreyfuss G. Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. Molecular and Cellular Biology. 20: 8536-47. PMID 11046149 DOI: 10.1128/MCB.20.22.8536-8547.2000  1
2000 Mizukami K, Kamma H, Ishikawa M, Dreyfuss G. Immunohistochemical study of the hnRNP A2 and B1 in the rat forebrain. Neuroreport. 11: 3099-102. PMID 11043530  1
2000 Kataoka N, Yong J, Kim VN, Velazquez F, Perkinson RA, Wang F, Dreyfuss G. Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm. Molecular Cell. 6: 673-82. PMID 11030346  1
2000 Paushkin S, Charroux B, Abel L, Perkinson RA, Pellizzoni L, Dreyfuss G. The survival motor neuron protein of Schizosacharomyces pombe. Conservation of survival motor neuron interaction domains in divergent organisms. The Journal of Biological Chemistry. 275: 23841-6. PMID 10816558 DOI: 10.1074/jbc.M001441200  1
2000 Charroux B, Pellizzoni L, Perkinson RA, Yong J, Shevchenko A, Mann M, Dreyfuss G. Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. The Journal of Cell Biology. 148: 1177-86. PMID 10725331 DOI: 10.1083/jcb.148.6.1177  1
1999 Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G. Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. The Journal of Cell Biology. 147: 1181-94. PMID 10601333 DOI: 10.1083/jcb.147.6.1181  1
1999 Swanson MS, Dreyfuss G. Preparation of heterogeneous nuclear ribonucleoprotein complexes. Methods in Molecular Biology (Clifton, N.J.). 118: 299-308. PMID 10549532 DOI: 10.1385/1-59259-676-2:299  1
1999 Fischer U, Pollard VW, Lührmann R, Teufel M, Michael MW, Dreyfuss G, Malim MH. Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle. Nucleic Acids Research. 27: 4128-34. PMID 10518602 DOI: 10.1093/nar/27.21.4128  1
1999 Pellizzoni L, Charroux B, Dreyfuss G. SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins. Proceedings of the National Academy of Sciences of the United States of America. 96: 11167-72. PMID 10500148 DOI: 10.1073/pnas.96.20.11167  1
1999 Kataoka N, Bachorik JL, Dreyfuss G. Transportin-SR, a nuclear import receptor for SR proteins. The Journal of Cell Biology. 145: 1145-52. PMID 10366588 DOI: 10.1083/jcb.145.6.1145  1
1999 Kamma H, Horiguchi H, Wan L, Matsui M, Fujiwara M, Fujimoto M, Yazawa T, Dreyfuss G. Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms. Experimental Cell Research. 246: 399-411. PMID 9925756 DOI: 10.1006/excr.1998.4323  1
1998 Pellizzoni L, Kataoka N, Charroux B, Dreyfuss G. A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing. Cell. 95: 615-24. PMID 9845364  1
1998 Siomi MC, Fromont M, Rain JC, Wan L, Wang F, Legrain P, Dreyfuss G. Functional conservation of the transportin nuclear import pathway in divergent organisms. Molecular and Cellular Biology. 18: 4141-8. PMID 9632798  1
1998 Hassfeld W, Chan EK, Mathison DA, Portman D, Dreyfuss G, Steiner G, Tan EM. Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P. Nucleic Acids Research. 26: 439-45. PMID 9421497 DOI: 10.1093/nar/26.2.439  1
1997 Fischer U, Liu Q, Dreyfuss G. The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis. Cell. 90: 1023-9. PMID 9323130  0.32
1997 Liu Q, Fischer U, Wang F, Dreyfuss G. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell. 90: 1013-21. PMID 9323129  0.32
1997 Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G. Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins. The Journal of Cell Biology. 138: 1181-92. PMID 9298975 DOI: 10.1083/jcb.138.6.1181  1
1997 Michael WM, Eder PS, Dreyfuss G. The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein. The Embo Journal. 16: 3587-98. PMID 9218800 DOI: 10.1093/emboj/16.12.3587  0.32
1997 Lefebvre S, Burlet P, Liu Q, Bertrandy S, Clermont O, Munnich A, Dreyfuss G, Melki J. Correlation between severity and SMN protein level in spinal muscular atrophy. Nature Genetics. 16: 265-9. PMID 9207792 DOI: 10.1038/ng0797-265  0.32
1997 Portman DS, O'Connor JP, Dreyfuss G. YRA1, an essential Saccharomyces cerevisiae gene, encodes a novel nuclear protein with RNA annealing activity. Rna (New York, N.Y.). 3: 527-37. PMID 9149233  1
1997 Izaurralde E, Jarmolowski A, Beisel C, Mattaj IW, Dreyfuss G, Fischer U. A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export. The Journal of Cell Biology. 137: 27-35. PMID 9105034 DOI: 10.1083/jcb.137.1.27  1
1996 Liu Q, Siomi H, Siomi MC, Fischer U, Zhang Y, Wan L, Dreyfuss G. Molecular characterization of the protein products of the fragile X syndrome gene and the survival of motor neurons gene. Cold Spring Harbor Symposia On Quantitative Biology. 61: 689-97. PMID 9246495  1
1996 Nakielny S, Siomi MC, Siomi H, Michael WM, Pollard V, Dreyfuss G. Transportin: nuclear transport receptor of a novel nuclear protein import pathway. Experimental Cell Research. 229: 261-6. PMID 8986607 DOI: 10.1006/excr.1996.0369  0.32
1996 Pollard VW, Michael WM, Nakielny S, Siomi MC, Wang F, Dreyfuss G. A novel receptor-mediated nuclear protein import pathway. Cell. 86: 985-94. PMID 8808633  0.32
1996 Dreyfuss G, Hentze M, Lamond AI. From transcript to protein. Cell. 85: 963-72. PMID 8674124 DOI: 10.1016/S0092-8674(00)81298-2  1
1996 Liu Q, Dreyfuss G. A novel nuclear structure containing the survival of motor neurons protein. The Embo Journal. 15: 3555-65. PMID 8670859  0.32
1996 Siomi MC, Zhang Y, Siomi H, Dreyfuss G. Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them. Molecular and Cellular Biology. 16: 3825-32. PMID 8668200  0.32
1995 Michael WM, Siomi H, Choi M, Piñol-Roma S, Nakielny S, Liu Q, Dreyfuss G. Signal sequences that target nuclear import and nuclear export of pre-mRNA-binding proteins. Cold Spring Harbor Symposia On Quantitative Biology. 60: 663-8. PMID 8824440  1
1995 Bustelo XR, Suen KL, Michael WM, Dreyfuss G, Barbacid M. Association of the vav proto-oncogene product with poly(rC)-specific RNA-binding proteins. Molecular and Cellular Biology. 15: 1324-32. PMID 7862126  1
1995 Siomi MC, Siomi H, Sauer WH, Srinivasan S, Nussbaum RL, Dreyfuss G. FXR1, an autosomal homolog of the fragile X mental retardation gene. The Embo Journal. 14: 2401-8. PMID 7781595  0.32
1995 Liu Q, Dreyfuss G. In vivo and in vitro arginine methylation of RNA-binding proteins. Molecular and Cellular Biology. 15: 2800-8. PMID 7739561  0.32
1995 Kamma H, Portman DS, Dreyfuss G. Cell type-specific expression of hnRNP proteins. Experimental Cell Research. 221: 187-96. PMID 7589244 DOI: 10.1006/excr.1995.1366  1
1995 Zhang Y, O'Connor JP, Siomi MC, Srinivasan S, Dutra A, Nussbaum RL, Dreyfuss G. The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. The Embo Journal. 14: 5358-66. PMID 7489725  0.6
1994 Siomi H, Choi M, Siomi MC, Nussbaum RL, Dreyfuss G. Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome. Cell. 77: 33-9. PMID 8156595  0.32
1994 Matunis EL, Kelley R, Dreyfuss G. Essential role for a heterogeneous nuclear ribonucleoprotein (hnRNP) in oogenesis: hrp40 is absent from the germ line in the dorsoventral mutant squid. Proceedings of the National Academy of Sciences of the United States of America. 91: 2781-4. PMID 8146191  1
1994 Görlach M, Burd CG, Dreyfuss G. The determinants of RNA-binding specificity of the heterogeneous nuclear ribonucleoprotein C proteins. The Journal of Biological Chemistry. 269: 23074-8. PMID 8083209  1
1994 Burd CG, Dreyfuss G. Conserved structures and diversity of functions of RNA-binding proteins. Science (New York, N.Y.). 265: 615-21. PMID 8036511  1
1994 Görlach M, Burd CG, Dreyfuss G. The mRNA poly(A)-binding protein: localization, abundance, and RNA-binding specificity. Experimental Cell Research. 211: 400-7. PMID 7908267 DOI: 10.1006/excr.1994.1104  1
1994 Matunis MJ, Matunis EL, Dreyfuss G. Isolation and characterization of RNA-binding proteins from Drosophila melanogaster. Methods in Cell Biology. 44: 191-205. PMID 7707952  1
1994 Weng Z, Thomas SM, Rickles RJ, Taylor JA, Brauer AW, Seidel-Dugan C, Michael WM, Dreyfuss G, Brugge JS. Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains. Molecular and Cellular Biology. 14: 4509-21. PMID 7516469  1
1994 Matunis MJ, Xing J, Dreyfuss G. The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. Nucleic Acids Research. 22: 1059-67. PMID 7512260  1
1994 Burd CG, Dreyfuss G. RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing. The Embo Journal. 13: 1197-204. PMID 7510636  1
1994 Portman DS, Dreyfuss G. RNA annealing activities in HeLa nuclei. The Embo Journal. 13: 213-21. PMID 7508381  1
1993 Matunis EL, Matunis MJ, Dreyfuss G. Association of individual hnRNP proteins and snRNPs with nascent transcripts. The Journal of Cell Biology. 121: 219-28. PMID 8468343  1
1993 Siomi H, Matunis MJ, Michael WM, Dreyfuss G. The pre-mRNA binding K protein contains a novel evolutionarily conserved motif. Nucleic Acids Research. 21: 1193-8. PMID 8464704  1
1993 Datar KV, Dreyfuss G, Swanson MS. The human hnRNP M proteins: identification of a methionine/arginine-rich repeat motif in ribonucleoproteins. Nucleic Acids Research. 21: 439-46. PMID 8441656 DOI: 10.1093/nar/21.3.439  1
1993 Matunis MJ, Matunis EL, Dreyfuss G. PUB1: a major yeast poly(A)+ RNA-binding protein. Molecular and Cellular Biology. 13: 6114-23. PMID 8413213  1
1993 Piñol-Roma S, Dreyfuss G. Cell cycle-regulated phosphorylation of the pre-mRNA-binding (heterogeneous nuclear ribonucleoprotein) C proteins. Molecular and Cellular Biology. 13: 5762-70. PMID 8395012  1
1993 Dreyfuss G, Matunis MJ, Piñol-Roma S, Burd CG. hnRNP proteins and the biogenesis of mRNA. Annual Review of Biochemistry. 62: 289-321. PMID 8352591 DOI: 10.1146/  1
1993 Takimoto M, Tomonaga T, Matunis M, Avigan M, Krutzsch H, Dreyfuss G, Levens D. Specific binding of heterogeneous ribonucleoprotein particle protein K to the human c-myc promoter, in vitro. The Journal of Biological Chemistry. 268: 18249-58. PMID 8349701  1
1993 Ishikawa F, Matunis MJ, Dreyfuss G, Cech TR. Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Molecular and Cellular Biology. 13: 4301-10. PMID 8321232  1
1993 Görlach M, Burd CG, Portman DS, Dreyfuss G. The hnRNP proteins. Molecular Biology Reports. 18: 73-8. PMID 8232298 DOI: 10.1007/BF00986759  1
1993 Soulard M, Della Valle V, Siomi MC, Piñol-Roma S, Codogno P, Bauvy C, Bellini M, Lacroix JC, Monod G, Dreyfuss G. hnRNP G: sequence and characterization of a glycosylated RNA-binding protein. Nucleic Acids Research. 21: 4210-7. PMID 7692398 DOI: 10.1093/nar/21.18.4210  0.32
1993 Siomi H, Siomi MC, Nussbaum RL, Dreyfuss G. The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein. Cell. 74: 291-8. PMID 7688265  0.32
1992 Matunis EL, Matunis MJ, Dreyfuss G. Characterization of the major hnRNP proteins from Drosophila melanogaster. The Journal of Cell Biology. 116: 257-69. PMID 1730754  1
1992 Matunis MJ, Matunis EL, Dreyfuss G. Isolation of hnRNP complexes from Drosophila melanogaster. The Journal of Cell Biology. 116: 245-55. PMID 1730753  1
1992 Matunis MJ, Michael WM, Dreyfuss G. Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein. Molecular and Cellular Biology. 12: 164-71. PMID 1729596  1
1992 Ghetti A, Piñol-Roma S, Michael WM, Morandi C, Dreyfuss G. hnRNP I, the polypyrimidine tract-binding protein: distinct nuclear localization and association with hnRNAs. Nucleic Acids Research. 20: 3671-8. PMID 1641332 DOI: 10.1093/nar/20.14.3671  1
1992 Kiledjian M, Dreyfuss G. Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. The Embo Journal. 11: 2655-64. PMID 1628625  1
1992 Bennett M, Piñol-Roma S, Staknis D, Dreyfuss G, Reed R. Differential binding of heterogeneous nuclear ribonucleoproteins to mRNA precursors prior to spliceosome assembly in vitro. Molecular and Cellular Biology. 12: 3165-75. PMID 1620124  1
1992 Wittekind M, Görlach M, Friedrichs M, Dreyfuss G, Mueller L. 1H, 13C, and 15N NMR assignments and global folding pattern of the RNA-binding domain of the human hnRNP C proteins. Biochemistry. 31: 6254-65. PMID 1385725  1
1992 Ludevid MD, Freire MA, Gómez J, Burd CG, Albericio F, Giralt E, Dreyfuss G, Pagès M. RNA binding characteristics of a 16 kDa glycine-rich protein from maize. The Plant Journal : For Cell and Molecular Biology. 2: 999-1003. PMID 1302645  1
1991 Piñol-Roma S, Dreyfuss G. Transcription-dependent and transcription-independent nuclear transport of hnRNP proteins. Science (New York, N.Y.). 253: 312-4. PMID 1857966  1
1991 Burd CG, Matunis EL, Dreyfuss G. The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities. Molecular and Cellular Biology. 11: 3419-24. PMID 1675426  1
1990 Piñol-Roma S, Swanson M, Görlach M, Burd C, Matunis M, Matunis E, Michael M, Dreyfuss G. Recent studies on hnRNP complexes. Molecular Biology Reports. 14: 85. PMID 2362581 DOI: 10.1007/BF00360426  1
1990 Piñol-Roma S, Swanson MS, Matunis MJ, Dreyfuss G. Purification and characterization of proteins of heterogeneous nuclear ribonucleoprotein complexes by affinity chromatography. Methods in Enzymology. 181: 326-31. PMID 2143257 DOI: 10.1016/0076-6879(90)81133-F  1
1990 Piñol-Roma S, Choi YD, Dreyfuss G. Immunological methods for purification and characterization of heterogeneous nuclear ribonucleoprotein particles. Methods in Enzymology. 181: 317-25. PMID 2143256 DOI: 10.1016/0076-6879(90)81132-E  1
1989 Piñol-Roma S, Swanson MS, Gall JG, Dreyfuss G. A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts. The Journal of Cell Biology. 109: 2575-87. PMID 2687284 DOI: 10.1083/jcb.109.6.2575  1
1989 Burd CG, Swanson MS, Görlach M, Dreyfuss G. Primary structures of the heterogeneous nuclear ribonucleoprotein A2, B1, and C2 proteins: a diversity of RNA binding proteins is generated by small peptide inserts. Proceedings of the National Academy of Sciences of the United States of America. 86: 9788-92. PMID 2557628 DOI: 10.1073/pnas.86.24.9788  1
1989 Mortenson E, Dreyfuss G. RNP in maize protein. Nature. 337: 312. PMID 2521378 DOI: 10.1038/337312b0  1
1989 Piñol-Roma S, Adam SA, Choi YD, Dreyfuss G. Ultraviolet-induced cross-linking of RNA to proteins in vivo. Methods in Enzymology. 180: 410-8. PMID 2515420 DOI: 10.1016/0076-6879(89)80114-4  1
1989 Bandziulis RJ, Swanson MS, Dreyfuss G. RNA-binding proteins as developmental regulators. Genes & Development. 3: 431-7. PMID 2470643  1
1988 Swanson MS, Dreyfuss G. Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities. Molecular and Cellular Biology. 8: 2237-41. PMID 3386636  1
1988 Swanson MS, Dreyfuss G. RNA binding specificity of hnRNP proteins: a subset bind to the 3' end of introns. The Embo Journal. 7: 3519-29. PMID 3208740  1
1988 Piñol-Roma S, Choi YD, Matunis MJ, Dreyfuss G. Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins. Genes & Development. 2: 215-27. PMID 3129338  1
1988 Dreyfuss G, Swanson MS, Piñol-Roma S. Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation. Trends in Biochemical Sciences. 13: 86-91. PMID 3072706 DOI: 10.1016/0968-0004(88)90046-1  1
1981 Boss MA, Dreyfuss G, Baltimore D. Localization of the Abelson murine leukemia virus protein in a detergent-insoluble subcellular matrix: architecture of the protein. Journal of Virology. 40: 472-81. PMID 6172595  0.72
1978 Dreyfuss G, Schwartz KJ, Blout ER. Compartmentalization of cyclic AMP-dependent protein kinases in human erythrocytes. Proceedings of the National Academy of Sciences of the United States of America. 75: 5926-30. PMID 216002  0.56
1978 Dreyfuss G, Schwartz K, Blout ER, Barrio JR, Liu FT, Leonard NJ. Fluorescent photoaffinity labeling: adenosine 3',5'-cyclic monophosphate receptor sites. Proceedings of the National Academy of Sciences of the United States of America. 75: 1199-203. PMID 206888  0.56
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