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Hanping Feng, Ph.D. - Publications

Affiliations: 
2002 University of Arizona, Tucson, AZ 
Area:
Immunology, Oncology, Microbiology Biology
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55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang J, Ortiz C, Fontenot L, Mukhopadhyay R, Xie Y, Chen X, Feng H, Pothoulakis C, Koon HW. The therapeutic mechanism macrophage inflammatory protein 1 alpha (MIP-1α/CCL3) neutralizing antibody in Clostridium difficile infection in mice. The Journal of Infectious Diseases. PMID 31793629 DOI: 10.1093/Infdis/Jiz640  0.341
2019 Chen P, Lam KH, Liu Z, Mindlin FA, Chen B, Gutierrez CB, Huang L, Zhang Y, Hamza T, Feng H, Matsui T, Bowen ME, Perry K, Jin R. Structure of the full-length Clostridium difficile toxin B. Nature Structural & Molecular Biology. PMID 31308519 DOI: 10.2210/Pdb6Oq6/Pdb  0.349
2019 Simeon R, Jiang M, Chamoun-Emanuelli AM, Yu H, Zhang Y, Meng R, Peng Z, Jakana J, Zhang J, Feng H, Chen Z. Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B. Plos Biology. 17: e3000311. PMID 31233493 DOI: 10.1371/Journal.Pbio.3000311  0.357
2018 Tam J, Hamza T, Ma B, Chen K, Beilhartz GL, Ravel J, Feng H, Melnyk RA. Host-targeted niclosamide inhibits C. difficile virulence and prevents disease in mice without disrupting the gut microbiota. Nature Communications. 9: 5233. PMID 30531960 DOI: 10.1038/S41467-018-07705-W  0.354
2018 Zhang Y, Li S, Yang Z, Shi L, Yu H, Salerno-Goncalves R, Saint Fleur A, Feng H. Cysteine Protease-Mediated Autocleavage of Toxins Regulates Their Proinflammatory Activity. Cellular and Molecular Gastroenterology and Hepatology. 5: 611-625. PMID 29930981 DOI: 10.1016/J.Jcmgh.2018.01.022  0.333
2017 Zhang Y, Yang Z, Gao S, Hamza T, Yfantis HG, Lipsky M, Feng H. The role of purified Clostridium difficile glucosylating toxins in disease pathogenesis utilizing a murine cecum injection model. Anaerobe. PMID 29031928 DOI: 10.1016/J.Anaerobe.2017.10.006  0.371
2016 Chen S, Wang H, Gu H, Sun C, Li S, Feng H, Wang J. Identification of an Essential Region for Translocation of Clostridium difficile Toxin B. Toxins. 8. PMID 27537911 DOI: 10.3390/Toxins8080241  0.331
2016 Yang Z, Shi L, Yu H, Zhang Y, Chen K, Fleur AS, Bai G, Feng H. Intravenous adenovirus expressing a multi-specific, single-domain antibody neutralizing TcdA and TcdB protects mice from Clostridium difficile infection. Pathogens and Disease. PMID 27502696 DOI: 10.1093/Femspd/Ftw078  0.362
2016 Maldarelli GA, Matz H, Gao S, Chen K, Hamza T, Yfantis HG, Feng H, Donnenberg MS. Pilin Vaccination Stimulates Weak Antibody Responses and Provides No Protection in a C57Bl/6 Murine Model of Acute Clostridium difficile Infection. Journal of Vaccines & Vaccination. 7. PMID 27375958 DOI: 10.4172/2157-7560.1000321  0.371
2016 Mehta KK, Paskaleva EE, Wu X, Grover N, Mundra RV, Chen K, Zhang Y, Yang Z, Feng H, Dordick JS, Kane RS. Newly identified bacteriolytic enzymes that target a wide range of clinical isolates of Clostridium difficile. Biotechnology and Bioengineering. PMID 27260850 DOI: 10.1002/Bit.26029  0.339
2016 Zhang Y, Feng H. Pathogenic effects of glucosyltransferase from Clostridium difficile toxins. Pathogens and Disease. PMID 27044305 DOI: 10.1093/Femspd/Ftw024  0.351
2015 Hamza T, Zhang Z, Melnyk RA, Feng H. Defective Mutations within the Translocation Domain of Clostridium difficile Toxin B Impair Disease Pathogenesis. Pathogens and Disease. PMID 26507679 DOI: 10.1093/Femspd/Ftv098  0.323
2015 Yang Z, Zhang Y, Huang T, Feng H. Glucosyltransferase activity of Clostridium difficile Toxin B is essential for disease pathogenesis. Gut Microbes. 221-224. PMID 26091306 DOI: 10.1080/19490976.2015.1062965  0.322
2015 Yu H, Chen K, Wu J, Yang Z, Shi L, Barlow LL, Aronoff DM, Garey KW, Savidge TC, von Rosenvinge EC, Kelly CP, Feng H. Identification of toxemia in patients with Clostridium difficile infection. Plos One. 10: e0124235. PMID 25885671 DOI: 10.1371/Journal.Pone.0124235  0.334
2015 Huang T, Perez-Cordon G, Shi L, Li G, Sun X, Wang X, Wang J, Feng H. Clostridium difficile toxin B intoxicated mouse colonic epithelial CT26 cells stimulate the activation of dendritic cells. Pathogens and Disease. 73. PMID 25743476 DOI: 10.1093/Femspd/Ftv008  0.406
2015 Zhang Y, Hamza T, Gao S, Feng H. Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides. Biochemical and Biophysical Research Communications. 459: 259-63. PMID 25725153 DOI: 10.1016/J.Bbrc.2015.02.095  0.338
2015 Yuan P, Zhang H, Cai C, Zhu S, Zhou Y, Yang X, He R, Li C, Guo S, Li S, Huang T, Perez-Cordon G, Feng H, Wei W. Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B. Cell Research. 25: 157-68. PMID 25547119 DOI: 10.1038/Cr.2014.169  0.401
2015 Yang Z, Ramsey J, Hamza T, Zhang Y, Li S, Yfantis HG, Lee D, Hernandez LD, Seghezzi W, Furneisen JM, Davis NM, Therien AG, Feng H. Mechanisms of protection against Clostridium difficile infection by the monoclonal antitoxin antibodies actoxumab and bezlotoxumab. Infection and Immunity. 83: 822-31. PMID 25486992 DOI: 10.1128/Iai.02897-14  0.353
2015 Li S, Shi L, Yang Z, Zhang Y, Perez-Cordon G, Huang T, Ramsey J, Oezguen N, Savidge TC, Feng H. Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis. Infection and Immunity. 83: 502-13. PMID 25404023 DOI: 10.1128/Iai.02316-14  0.354
2014 Huang T, Li S, Li G, Tian Y, Wang H, Shi L, Perez-Cordon G, Mao L, Wang X, Wang J, Feng H. Utility of Clostridium difficile toxin B for inducing anti-tumor immunity. Plos One. 9: e110826. PMID 25340750 DOI: 10.1371/Journal.Pone.0110826  0.463
2014 Yang Z, Schmidt D, Liu W, Li S, Shi L, Sheng J, Chen K, Yu H, Tremblay JM, Chen X, Piepenbrink KH, Sundberg EJ, Kelly CP, Bai G, Shoemaker CB, ... Feng H, et al. A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice. The Journal of Infectious Diseases. 210: 964-72. PMID 24683195 DOI: 10.1093/Infdis/Jiu196  0.359
2014 Perez-Cordon G, Yang G, Zhou B, Nie W, Li S, Shi L, Tzipori S, Feng H. Interaction of Cryptosporidium parvum with mouse dendritic cells leads to their activation and parasite transportation to mesenteric lymph nodes. Pathogens and Disease. 70: 17-27. PMID 23913680 DOI: 10.1111/2049-632X.12078  0.383
2013 Li S, Shi L, Yang Z, Feng H. Cytotoxicity of Clostridium difficile toxin B does not require cysteine protease-mediated autocleavage and release of the glucosyltransferase domain into the host cell cytosol. Pathogens and Disease. 67: 11-8. PMID 23620115 DOI: 10.1111/2049-632X.12016  0.36
2013 Zhang Y, Shi L, Li S, Yang Z, Standley C, Yang Z, ZhuGe R, Savidge T, Wang X, Feng H. A segment of 97 amino acids within the translocation domain of Clostridium difficile toxin B is essential for toxicity. Plos One. 8: e58634. PMID 23484044 DOI: 10.1371/Journal.Pone.0058634  0.364
2012 Tian Y, Huang T, Li G, Liu J, Wang X, Feng H, Wang J. Retraction notice to “Apoptosis of CT26 colorectal cancer cells induced by Clostridium difficile toxin A stimulates potent anti-tumor immunity” [Biochem. Biophys. Res. Commun. 422 (2012) 15–21] Biochemical and Biophysical Research Communications. 425: 119. PMID 23071973 DOI: 10.1016/J.Bbrc.2012.07.039  0.317
2012 Butler MM, Shinabarger DL, Citron DM, Kelly CP, Dvoskin S, Wright GE, Feng H, Tzipori S, Bowlin TL. MBX-500, a hybrid antibiotic with in vitro and in vivo efficacy against toxigenic Clostridium difficile. Antimicrobial Agents and Chemotherapy. 56: 4786-92. PMID 22733075 DOI: 10.1128/Aac.00508-12  0.332
2012 Wang H, Sun X, Zhang Y, Li S, Chen K, Shi L, Nie W, Kumar R, Tzipori S, Wang J, Savidge T, Feng H. A chimeric toxin vaccine protects against primary and recurrent Clostridium difficile infection. Infection and Immunity. 80: 2678-88. PMID 22615245 DOI: 10.1128/Iai.00215-12  0.398
2012 Tian Y, Huang T, Li G, Liu J, Wang X, Feng H, Wang J. Retracted: Apoptosis of CT26 colorectal cancer cells induced by Clostridium difficile toxin A stimulates potent anti-tumor immunity. Biochemical and Biophysical Research Communications. 422: 15-21. PMID 22548800 DOI: 10.1016/J.Bbrc.2012.04.068  0.412
2012 Oezguen N, Power TD, Urvil P, Feng H, Pothoulakis C, Stamler JS, Braun W, Savidge TC. Clostridial toxins: sensing a target in a hostile gut environment. Gut Microbes. 3: 35-41. PMID 22356854 DOI: 10.4161/Gmic.19250  0.336
2012 Steele J, Chen K, Sun X, Zhang Y, Wang H, Tzipori S, Feng H. Systemic dissemination of Clostridium difficile toxins A and B is associated with severe, fatal disease in animal models. The Journal of Infectious Diseases. 205: 384-91. PMID 22147798 DOI: 10.1093/Infdis/Jir748  0.321
2012 Krautz-Peterson G, Zhang Y, Chen K, Oyler GA, Feng H, Shoemaker CB. Retargeting Clostridium difficile Toxin B to Neuronal Cells as a Potential Vehicle for Cytosolic Delivery of Therapeutic Biomolecules to Treat Botulism. Journal of Toxicology. 2012: 760142. PMID 21941543 DOI: 10.1155/2012/760142  0.309
2011 Savidge TC, Urvil P, Oezguen N, Ali K, Choudhury A, Acharya V, Pinchuk I, Torres AG, English RD, Wiktorowicz JE, Loeffelholz M, Kumar R, Shi L, Nie W, Braun W, ... ... Feng H, et al. Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins. Nature Medicine. 17: 1136-41. PMID 21857653 DOI: 10.1038/Nm.2405  0.36
2011 Sun X, Wang H, Zhang Y, Chen K, Davis B, Feng H. Mouse relapse model of Clostridium difficile infection. Infection and Immunity. 79: 2856-64. PMID 21576341 DOI: 10.1128/Iai.01336-10  0.364
2011 Zhang Q, Feng X, Nie W, Golenbock DT, Mayanja-Kizza H, Tzipori S, Feng H. MyD88-dependent pathway is essential for the innate immunity to Enterocytozoon bieneusi Parasite Immunology. 33: 217-225. PMID 21204848 DOI: 10.1111/J.1365-3024.2010.01269.X  0.383
2011 Perez-Cordon G, Nie W, Schmidt D, Tzipori S, Feng H. Involvement of host calpain in the invasion of Cryptosporidium parvum. Microbes and Infection / Institut Pasteur. 13: 103-7. PMID 21087681 DOI: 10.1016/J.Micinf.2010.10.007  0.321
2010 Sun X, Savidge T, Feng H. The enterotoxicity of Clostridium difficile toxins. Toxins. 2: 1848-80. PMID 22069662 DOI: 10.3390/Toxins2071848  0.414
2010 Steele J, Feng H, Parry N, Tzipori S. Piglet models of acute or chronic Clostridium difficile illness. The Journal of Infectious Diseases. 201: 428-34. PMID 20039803 DOI: 10.1086/649799  0.307
2009 Sun X, He X, Tzipori S, Gerhard R, Feng H. Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-alpha by macrophages. Microbial Pathogenesis. 46: 298-305. PMID 19324080 DOI: 10.1016/J.Micpath.2009.03.002  0.316
2009 He X, Sun X, Wang J, Wang X, Zhang Q, Tzipori S, Feng H. Antibody-enhanced, Fc gamma receptor-mediated endocytosis of Clostridium difficile toxin A. Infection and Immunity. 77: 2294-303. PMID 19307220 DOI: 10.1128/Iai.01577-08  0.39
2008 Yang G, Zhou B, Wang J, He X, Sun X, Nie W, Tzipori S, Feng H. Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium. Bmc Microbiology. 8: 192. PMID 18990232 DOI: 10.1186/1471-2180-8-192  0.302
2008 Krautz-Peterson G, Chapman-Bonofiglio S, Boisvert K, Feng H, Herman IM, Tzipori S, Sheoran AS. Intracellular neutralization of shiga toxin 2 by an a subunit-specific human monoclonal antibody. Infection and Immunity. 76: 1931-9. PMID 18285498 DOI: 10.1128/Iai.01282-07  0.366
2006 Feng H, Nie W, Bonilla R, Widmer G, Sheoran A, Tzipori S. Quantitative tracking of Cryptosporidium infection in cell culture with CFSE. The Journal of Parasitology. 92: 1350-4. PMID 17304819 DOI: 10.1645/Ge-853R.1  0.322
2006 Feng H, Nie W, Sheoran A, Zhang Q, Tzipori S. Bile acids enhance invasiveness of Cryptosporidium spp. into cultured cells. Infection and Immunity. 74: 3342-6. PMID 16714562 DOI: 10.1128/Iai.00169-06  0.321
2005 Feng H, Zhang D, Palliser D, Zhu P, Cai S, Schlesinger A, Maliszewski L, Lieberman J. Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 175: 421-32. PMID 15972676 DOI: 10.4049/Jimmunol.175.1.421  0.394
2005 Zhu P, Sang Y, Xu H, Zhao J, Xu R, Sun Y, Xu T, Wang X, Chen L, Feng H, Li C, Zhao S. ADAM22 plays an important role in cell adhesion and spreading with the assistance of 14-3-3. Biochemical and Biophysical Research Communications. 331: 938-46. PMID 15882968 DOI: 10.1016/J.Bbrc.2005.03.229  0.324
2005 Cai S, Dole VS, Bergmeier W, Scafidi J, Feng H, Wagner DD, Davis AE. A direct role for C1 inhibitor in regulation of leukocyte adhesion. Journal of Immunology (Baltimore, Md. : 1950). 174: 6462-6. PMID 15879149 DOI: 10.4049/Jimmunol.174.10.6462  0.331
2005 Shi L, Keefe D, Durand E, Feng H, Zhang D, Lieberman J. Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 174: 5456-61. PMID 15843543 DOI: 10.4049/Jimmunol.174.9.5456  0.368
2004 Feng H, Zeng Y, Graner MW, Whitesell L, Katsanis E. Evidence for a Novel, Caspase-8-Independent, Fas Death Domain-Mediated Apoptotic Pathway. Journal of Biomedicine & Biotechnology. 2004: 41-51. PMID 15123887 DOI: 10.1155/S1110724304308041  0.588
2004 Zeng Y, Graner MW, Feng H, Li G, Katsanis E. Imatinib mesylate effectively combines with chaperone-rich cell lysate-loaded dendritic cells to treat bcr-abl+ murine leukemia. International Journal of Cancer. Journal International Du Cancer. 110: 251-9. PMID 15069690 DOI: 10.1002/Ijc.20115  0.656
2003 Graner MW, Zeng Y, Feng H, Katsanis E. Tumor-derived chaperone-rich cell lysates are effective therapeutic vaccines against a variety of cancers. Cancer Immunology, Immunotherapy : Cii. 52: 226-34. PMID 12669247 DOI: 10.1007/S00262-002-0359-2  0.604
2003 Zeng Y, Feng H, Graner MW, Katsanis E. Tumor-derived, chaperone-rich cell lysate activates dendritic cells and elicits potent antitumor immunity. Blood. 101: 4485-91. PMID 12576309 DOI: 10.1182/Blood-2002-10-3108  0.646
2003 Feng H, Zeng Y, Graner MW, Likhacheva A, Katsanis E. Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity. Blood. 101: 245-52. PMID 12393411 DOI: 10.1182/Blood-2002-05-1580  0.663
2002 Feng H, Zeng Y, Graner MW, Katsanis E. Stressed apoptotic tumor cells stimulate dendritic cells and induce specific cytotoxic T cells. Blood. 100: 4108-15. PMID 12393401 DOI: 10.1182/Blood-2002-05-1389  0.65
2001 Feng H, Zeng Y, Whitesell L, Katsanis E. Stressed apoptotic tumor cells express heat shock proteins and elicit tumor-specific immunity. Blood. 97: 3505-12. PMID 11369644 DOI: 10.1182/Blood.V97.11.3505  0.662
2001 He L, Feng H, Raymond A, Kreeger M, Zeng Y, Graner M, Whitesell L, Katsanis E. Dendritic-cell-peptide immunization provides immunoprotection against bcr-abl-positive leukemia in mice. Cancer Immunology, Immunotherapy : Cii. 50: 31-40. PMID 11315508 DOI: 10.1007/Pl00006680  0.65
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