Greg E. Lemke - Publications

Affiliations: 
Salk Institute for Biological Studies, La Jolla, CA, United States 
 Neurosciences University of California, San Diego, La Jolla, CA 
Area:
Development

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Year Citation  Score
2024 Miao S, Fourgeaud L, Burrola PG, Stern S, Zhang Y, Happonen KE, Novak SW, Gage FH, Lemke G. Tyro3 promotes the maturation of glutamatergic synapses. Frontiers in Neuroscience. 18: 1327423. PMID 38410160 DOI: 10.3389/fnins.2024.1327423  0.721
2022 Huang Y, Lemke G. Adaptable toolbox to characterize Alzheimer's disease pathology in mouse models. Star Protocols. 3: 101891. PMID 36472212 DOI: 10.1016/j.xpro.2022.101891  0.745
2022 Huang Y, Lemke G. Early death in a mouse model of Alzheimer's disease exacerbated by microglial loss of TAM receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 119: e2204306119. PMID 36191221 DOI: 10.1073/pnas.2204306119  0.757
2022 Jiménez-García L, Mayer C, Burrola PG, Huang Y, Shokhirev MN, Lemke G. The TAM receptor tyrosine kinases Axl and Mer drive the maintenance of highly phagocytic macrophages. Frontiers in Immunology. 13: 960401. PMID 35967387 DOI: 10.3389/fimmu.2022.960401  0.767
2022 Lemke G, Huang Y. The dense-core plaques of Alzheimer's disease are granulomas. The Journal of Experimental Medicine. 219. PMID 35731195 DOI: 10.1084/jem.20212477  0.754
2021 Huang Y, Happonen KE, Burrola PG, O'Connor C, Hah N, Huang L, Nimmerjahn A, Lemke G. Microglia use TAM receptors to detect and engulf amyloid β plaques. Nature Immunology. PMID 33859405 DOI: 10.1038/s41590-021-00913-5  0.767
2020 Diaz-Aparicio I, Paris I, Sierra-Torre V, Plaza-Zabala A, Rodríguez-Iglesias N, Márquez-Ropero M, Beccari S, Huguet P, Abiega O, Alberdi E, Matute C, Bernales I, Schulz A, Otrokocsi L, Sperlagh B, ... ... Lemke G, et al. Microglia actively remodel adult hippocampal neurogenesis through the phagocytosis secretome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31896673 DOI: 10.1523/Jneurosci.0993-19.2019  0.344
2019 Lemke G. How macrophages deal with death. Nature Reviews Immunology. 19: 539-549. PMID 31019284 DOI: 10.1038/S41577-019-0167-Y  0.344
2019 McShane L, Tabas I, Lemke G, Kurowska-Stolarska M, Maffia P. TAM Receptors in Cardiovascular Disease. Cardiovascular Research. PMID 30980657 DOI: 10.1093/Cvr/Cvz100  0.313
2017 Lemke G. Phosphatidylserine Is the Signal for TAM Receptors and Their Ligands. Trends in Biochemical Sciences. 42: 738-748. PMID 28734578 DOI: 10.1016/J.Tibs.2017.06.004  0.311
2017 Savier E, Eglen SJ, Bathélémy A, Perraut M, Pfrieger FW, Lemke G, Reber M. A molecular mechanism for the topographic alignment of convergent neural maps. Elife. 6. PMID 28322188 DOI: 10.7554/Elife.20470  0.764
2017 Tufail Y, Cook D, Fourgeaud L, Powers CJ, Merten K, Clark CL, Hoffman E, Ngo A, Sekiguchi KJ, O'Shea CC, Lemke G, Nimmerjahn A. Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia. Neuron. PMID 28111081 DOI: 10.1016/J.Neuron.2016.12.021  0.732
2016 Fourgeaud L, Través PG, Tufail Y, Leal-Bailey H, Lew ED, Burrola PG, Callaway P, Zagórska A, Rothlin CV, Nimmerjahn A, Lemke G. TAM receptors regulate multiple features of microglial physiology. Nature. PMID 27049947 DOI: 10.1038/Nature17630  0.759
2016 Savier E, Eglen SJ, Bathélémy A, Perraut M, Pfrieger FW, Lemke G, Reber M. Author response: A molecular mechanism for the topographic alignment of convergent neural maps Elife. DOI: 10.7554/Elife.20470.029  0.745
2015 Lemke G. Adopting ALK and LTK Proceedings of the National Academy of Sciences of the United States of America. 112: 15783-15784. PMID 26676577 DOI: 10.1073/Pnas.1521923113  0.31
2015 Miner JJ, Daniels BP, Shrestha B, Proenca-Modena JL, Lew ED, Lazear HM, Gorman MJ, Lemke G, Klein RS, Diamond MS. The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity. Nature Medicine. PMID 26523970 DOI: 10.1038/Nm.3974  0.323
2015 Dransfield I, Zagórska A, Lew ED, Michail K, Lemke G. Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells. Cell Death & Disease. 6: e1646. PMID 25695599 DOI: 10.1038/Cddis.2015.18  0.315
2014 Lemke G, Julius D. Stephen F. Heinemann: A true original. Proceedings of the National Academy of Sciences of the United States of America. 111: 14314-5. PMID 25258411 DOI: 10.1073/pnas.1416208111  0.482
2014 Zagórska A, Través PG, Lew ED, Dransfield I, Lemke G. Diversification of TAM receptor tyrosine kinase function. Nature Immunology. 15: 920-8. PMID 25194421 DOI: 10.1038/Ni.2986  0.349
2013 Lemke G. Biology of the TAM receptors Cold Spring Harbor Perspectives in Biology. 5. PMID 24186067 DOI: 10.1101/Cshperspect.A009076  0.332
2013 Bhattacharyya S, Zagórska A, Lew ED, Shrestha B, Rothlin CV, Naughton J, Diamond MS, Lemke G, Young JA. Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors. Cell Host & Microbe. 14: 136-47. PMID 23954153 DOI: 10.1016/J.Chom.2013.07.005  0.319
2013 Sullivan BM, Welch MJ, Lemke G, Oldstone MB. Is the TAM receptor Axl a receptor for lymphocytic choriomeningitis virus? Journal of Virology. 87: 4071-4. PMID 23325690 DOI: 10.1128/Jvi.03268-12  0.312
2012 Burstyn-Cohen T, Lew ED, Través PG, Burrola PG, Hash JC, Lemke G. Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis. Neuron. 76: 1123-32. PMID 23259948 DOI: 10.1016/J.Neuron.2012.10.015  0.375
2012 Meertens L, Carnec X, Lecoin MP, Ramdasi R, Guivel-Benhassine F, Lew E, Lemke G, Schwartz O, Amara A. The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. Cell Host & Microbe. 12: 544-57. PMID 23084921 DOI: 10.1016/J.Chom.2012.08.009  0.338
2012 Bauer T, Zagórska A, Jurkin J, Yasmin N, Köffel R, Richter S, Gesslbauer B, Lemke G, Strobl H. Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis Journal of Experimental Medicine. 209: 2033-2047. PMID 23071254 DOI: 10.1084/Jem.20120493  0.302
2011 Vacik T, Stubbs JL, Lemke G. A novel mechanism for the transcriptional regulation of Wnt signaling in development. Genes & Development. 25: 1783-95. PMID 21856776 DOI: 10.1101/gad.17227011  0.32
2011 Wang J, Zhang H, Young AG, Qiu R, Argalian S, Li X, Wu X, Lemke G, Lu Q. Transcriptome analysis of neural progenitor cells by a genetic dual reporter strategy. Stem Cells (Dayton, Ohio). 29: 1589-600. PMID 21805534 DOI: 10.1002/Stem.699  0.309
2011 Bevins N, Lemke G, Reber M. Genetic dissection of EphA receptor signaling dynamics during retinotopic mapping. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10302-10. PMID 21753007 DOI: 10.1523/Jneurosci.1652-11.2011  0.738
2011 Silva EAC, Chan PY, Joannas L, Burstyn-Cohen T, Lemke G, Ghosh S, Rothlin C. T cell derived Protein S inhibits the activation of Dendritic cells through the TAM receptors Axl and Mer: O-26. Inflammatory Bowel Diseases. 17. DOI: 10.1097/00054725-201112002-00028  0.315
2010 Rothlin CV, Lemke G. TAM receptor signaling and autoimmune disease Current Opinion in Immunology. 22: 740-746. PMID 21030229 DOI: 10.1016/J.Coi.2010.10.001  0.362
2010 Lemke G, Burstyn-Cohen T. TAM receptors and the clearance of apoptotic cells Annals of the New York Academy of Sciences. 1209: 23-29. PMID 20958312 DOI: 10.1111/J.1749-6632.2010.05744.X  0.358
2009 Triplett JW, Owens MT, Yamada J, Lemke G, Cang J, Stryker MP, Feldheim DA. Retinal input instructs alignment of visual topographic maps. Cell. 139: 175-85. PMID 19804762 DOI: 10.1016/j.cell.2009.08.028  0.342
2009 Burstyn-Cohen T, Heeb MJ, Lemke G. Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis Journal of Clinical Investigation. 119: 2942-2953. PMID 19729839 DOI: 10.1172/Jci39325  0.316
2009 Stanojcic M, Burstyn-Cohen T, Nashi N, Lemke G, Sakic B. Disturbed distribution of proliferative brain cells during lupus-like disease Brain Behavior and Immunity. 23: 1003-1013. PMID 19501646 DOI: 10.1016/J.Bbi.2009.05.061  0.317
2009 Kang KH, Lemke G, Kim JW. The PI3K–PTEN tug-of-war, oxidative stress and retinal degeneration Trends in Molecular Medicine. 15: 191-198. PMID 19380252 DOI: 10.1016/J.Molmed.2009.03.005  0.461
2009 Monuki ES, Lemke G. Molecular biology of myelination The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0007  0.562
2008 Kim JW, Kang KH, Burrola P, Mak TW, Lemke G. Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium Genes & Development. 22: 3147-3157. PMID 18997061 DOI: 10.1101/Gad.1700108  0.511
2008 Lemke G, Rothlin CV. Immunobiology of the TAM receptors Nature Reviews Immunology. 8: 327-336. PMID 18421305 DOI: 10.1038/Nri2303  0.35
2008 Gallarda BW, Bonanomi D, Müller D, Brown A, Alaynick WA, Andrews SE, Lemke G, Pfaff SL, Marquardt T. Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling. Science (New York, N.Y.). 320: 233-6. PMID 18403711 DOI: 10.1126/Science.1153758  0.312
2008 Angelillo-Scherrer A, Burnier L, Lambrechts D, Fish RJ, Tjwa M, Plaisance S, Sugamele R, DeMol M, Martinez-Soria E, Maxwell PH, Lemke G, Goff SP, Matsushima GK, Earp HS, Chanson M, et al. Role of Gas6 in erythropoiesis and anemia in mice. The Journal of Clinical Investigation. 118: 583-96. PMID 18188450 DOI: 10.1172/Jci30375  0.343
2007 Reber M, Hindges R, Lemke G. Eph receptors and ephrin ligands in axon guidance. Advances in Experimental Medicine and Biology. 621: 32-49. PMID 18269209 DOI: 10.1007/978-0-387-76715-4_3  0.716
2007 Rothlin CV, Ghosh S, Zuniga EI, Oldstone MB, Lemke G. TAM receptors are pleiotropic inhibitors of the innate immune response. Cell. 131: 1124-36. PMID 18083102 DOI: 10.1016/J.Cell.2007.10.034  0.306
2007 de Preux AS, Goosen K, Zhang W, Sima AA, Shimano H, Ouwens DM, Diamant M, Hillebrands JL, Rozing J, Lemke G, Beckmann JS, Smit AB, Verheijen MH, Chrast R. SREBP-1c expression in Schwann cells is affected by diabetes and nutritional status. Molecular and Cellular Neurosciences. 35: 525-34. PMID 17632011 DOI: 10.1016/j.mcn.2007.04.010  0.31
2007 Seitz HM, Camenisch TD, Lemke G, Earp HS, Matsushima GK. Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 5635-42. PMID 17442946 DOI: 10.4049/Jimmunol.178.9.5635  0.38
2007 Stephen LJ, Fawkes AL, Verhoeve A, Lemke G, Brown A. A critical role for the EphA3 receptor tyrosine kinase in heart development Developmental Biology. 302: 66-79. PMID 17046737 DOI: 10.1016/j.ydbio.2006.08.058  0.349
2006 Kim JW, Lemke G. Hedgehog-regulated localization of Vax2 controls eye development Genes & Development. 20: 2833-2847. PMID 17043310 DOI: 10.1101/Gad.1462706  0.506
2006 Prasad D, Rothlin CV, Burrola P, Burstyn-Cohen T, Lu Q, Garcia de Frutos P, Lemke G. TAM receptor function in the retinal pigment epithelium. Molecular and Cellular Neurosciences. 33: 96-108. PMID 16901715 DOI: 10.1016/J.Mcn.2006.06.011  0.62
2006 Sharif MN, Sosic D, Rothlin CV, Kelly E, Lemke G, Olson EN, Ivashkiv LB. Twist mediates suppression of inflammation by type I IFNs and Axl. The Journal of Experimental Medicine. 203: 1891-901. PMID 16831897 DOI: 10.1084/Jem.20051725  0.306
2006 Caraux A, Lu Q, Fernandez N, Riou S, Di Santo JP, Raulet DH, Lemke G, Roth C. Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases. Nature Immunology. 7: 747-54. PMID 16751775 DOI: 10.1038/Ni1353  0.364
2006 Shankar SL, O'Guin K, Kim M, Varnum B, Lemke G, Brosnan CF, Shafit-Zagardo B. Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5638-48. PMID 16723520 DOI: 10.1523/Jneurosci.5063-05.2006  0.319
2006 Lemke G. Neuregulin-1 and myelination. Science Signaling. 2006. PMID 16522871 DOI: 10.1126/Stke.3252006Pe11  0.355
2006 Radic MZ, Shah K, Zhang W, Lu Q, Lemke G, Hilliard GM. Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinases. Journal of Immunology (Baltimore, Md. : 1950). 176: 68-74. PMID 16365397 DOI: 10.4049/Jimmunol.176.1.68  0.355
2006 Lemke G, Reber M. EPHA receptors and topographic wiring of the eye to the brain International Journal of Developmental Neuroscience. 24: 490. DOI: 10.1016/J.Ijdevneu.2006.09.050  0.683
2005 Lemke G, Reber M. Retinotectal mapping: new insights from molecular genetics. Annual Review of Cell and Developmental Biology. 21: 551-80. PMID 16212507 DOI: 10.1146/Annurev.Cellbio.20.022403.093702  0.718
2005 Mui SH, Kim JW, Lemke G, Bertuzzi S. Vax genes ventralize the embryonic eye. Genes & Development. 19: 1249-59. PMID 15905411 DOI: 10.1101/gad.1276605  0.751
2004 Reber M, Burrola P, Lemke G. A relative signalling model for the formation of a topographic neural map. Nature. 431: 847-53. PMID 15483613 DOI: 10.1038/Nature02957  0.717
2003 Vaidya A, Pniak A, Lemke G, Brown A. EphA3 null mutants do not demonstrate motor axon guidance defects. Molecular and Cellular Biology. 23: 8092-8098. PMID 14585969 DOI: 10.1128/Mcb.23.22.8092-8098.2003  0.315
2003 Senderek J, Bergmann C, Stendel C, Kirfel J, Verpoorten N, De Jonghe P, Timmerman V, Chrast R, Verheijen MH, Lemke G, Battaloglu E, Parman Y, Erdem S, Tan E, Topaloglu H, et al. Mutations in a gene encoding a novel SH3/TPR domain protein cause autosomal recessive Charcot-Marie-Tooth type 4C neuropathy. American Journal of Human Genetics. 73: 1106-19. PMID 14574644 DOI: 10.1086/379525  0.309
2003 Verheijen MHG, Chrast R, Burrola P, Lemke G. Local regulation of fat metabolism in peripheral nerves Genes & Development. 17: 2450-2464. PMID 14522948 DOI: 10.1101/Gad.1116203  0.312
2003 Lemke G, Lu Q. Macrophage regulation by Tyro 3 family receptors. Current Opinion in Immunology. 15: 31-6. PMID 12495730 DOI: 10.1016/S0952-7915(02)00016-X  0.335
2002 Mui SH, Hindges R, O'Leary DD, Lemke G, Bertuzzi S. The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development (Cambridge, England). 129: 797-804. PMID 11830578  0.761
2001 Lu Q, Lemke G. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science. 293: 306-311. PMID 11452127 DOI: 10.1126/Science.1061663  0.364
2001 Labrador JP, Azcoitia V, Tuckermann J, Lin C, Olaso E, Mañes S, Brückner K, Goergen JL, Lemke G, Yancopoulos G, Angel P, Martínez C, Klein R. The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. Embo Reports. 2: 446-52. PMID 11375938 DOI: 10.1093/Embo-Reports/Kve094  0.352
2001 Lemke G. Glial control of neuronal development. Annual Review of Neuroscience. 24: 87-105. PMID 11283306 DOI: 10.1146/Annurev.Neuro.24.1.87  0.362
2000 Brown A, Yates PA, Burrola P, Ortuño D, Vaidya A, Jessell TM, Pfaff SL, O'Leary DD, Lemke G. Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling. Cell. 102: 77-88. PMID 10929715 DOI: 10.1016/S0092-8674(00)00012-X  0.408
2000 Kilpatrick TJ, Ortuño D, Bucci T, Lai C, Lemke G. Rat oligodendroglia express c-met and focal adhesion kinase, protein tyrosine kinases implicated in regulating epithelial cell motility Neuroscience Letters. 279: 5-8. PMID 10670774 DOI: 10.1016/S0304-3940(99)00928-3  0.377
2000 Syroid DE, Maycox PJ, Soilu-Hanninen M, Petratos S, Bucci T, Burrola P, Murray S, Cheema SS, Lee K, Lemke G, Kilpatrick TJ. Induction of Postnatal Schwann Cell Death by the Low-Affinity Neurotrophin Receptor In Vitro and after Axotomy The Journal of Neuroscience. 20: 5741-5747. DOI: 10.1523/Jneurosci.20-15-05741.2000  0.34
1999 Bertuzzi S, Hindges R, Mui SH, O'Leary DD, Lemke G. The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Genes & Development. 13: 3092-105. PMID 10601035 DOI: 10.1101/Gad.13.23.3092  0.76
1999 Lu Q, Gore M, Zhang Q, Camenisch T, Boast S, Casagranda F, Lai C, Skinner MK, Klein R, Matsushima GK, Earp HS, Goff SP, Lemke G. Tyro-3 family receptors are essential regulators of mammalian spermatogenesis. Nature. 398: 723-8. PMID 10227296 DOI: 10.1038/19554  0.396
1999 Krappa R, Nguyen A, Burrola P, Deretic D, Lemke G. Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes. Proceedings of the National Academy of Sciences of the United States of America. 96: 4633-4638. PMID 10200314 DOI: 10.1073/Pnas.96.8.4633  0.328
1999 Syroid DE, Zorick TS, Arbet-Engels C, Kilpatrick TJ, Eckhart W, Lemke G. A role for insulin-like growth factor-I in the regulation of Schwann cell survival. The Journal of Neuroscience. 19: 2059-2068. DOI: 10.1523/Jneurosci.19-06-02059.1999  0.376
1998 Lemke G. Chapter 14 Eph receptors and ligands in axon pathway choice, target recognition, and synaptogenesis Progress in Brain Research. 117: 171-176. PMID 9932408 DOI: 10.1016/S0079-6123(08)64015-7  0.361
1998 Désarnaud F, Do Thi AN, Brown AM, Lemke G, Suter U, Baulieu EE, Schumacher M. Progesterone stimulates the activity of the promoters of peripheral myelin protein-22 and protein zero genes in Schwann cells. Journal of Neurochemistry. 71: 1765-8. PMID 9751213 DOI: 10.1046/J.1471-4159.1998.71041765.X  0.348
1997 Shrivastava A, Radziejewski C, Campbell E, Kovac L, McGlynn M, Ryan TE, Davis S, Goldfarb MP, Glass DJ, Lemke G, Yancopoulos GD. An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors. Molecular Cell. 1: 25-34. PMID 9659900 DOI: 10.1016/S1097-2765(00)80004-0  0.322
1997 Brown AM, Lemke G. Multiple regulatory elements control transcription of the peripheral myelin protein zero gene. The Journal of Biological Chemistry. 272: 28939-47. PMID 9360965 DOI: 10.1074/Jbc.272.46.28939  0.322
1997 Maycox PR, Ortuño D, Burrola P, Kuhn R, Bieri PL, Arrezo JC, Lemke G. A Transgenic Mouse Model for Human Hereditary Neuropathy with Liability to Pressure Palsies Molecular and Cellular Neuroscience. 8: 405-416. PMID 9143558 DOI: 10.1006/Mcne.1997.0600  0.348
1997 Gassmann M, Lemke G. Neuregulins and neuregulin receptors in neural development. Current Opinion in Neurobiology. 7: 87-92. PMID 9039794 DOI: 10.1016/S0959-4388(97)80125-0  0.37
1996 Zorick TS, Syroid DE, Arroyo E, Scherer SS, Lemke G. The Transcription Factors SCIP and Krox-20 Mark Distinct Stages and Cell Fates in Schwann Cell Differentiation Molecular and Cellular Neurosciences. 8: 129-45. PMID 8954628 DOI: 10.1006/Mcne.1996.0052  0.404
1996 Zorick TS, Lemke G. Schwann cell differentiation Current Opinion in Cell Biology. 8: 870-876. PMID 8939676 DOI: 10.1016/S0955-0674(96)80090-1  0.382
1996 Kilpatrick TJ, Brown A, Lai C, Gassmann M, Goulding M, Lemke G. Expression of the Tyro4/Mek4/Cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets. Molecular and Cellular Neurosciences. 7: 62-74. PMID 8812059 DOI: 10.1006/Mcne.1996.0005  0.328
1996 Syroid DE, Maycox PR, Burrola PG, Liu N, Wen D, Lee K, Lemke G, Kilpatrick TJ. Cell death in the Schwann cell lineage and its regulation by neuregulin Proceedings of the National Academy of Sciences of the United States of America. 93: 9229-9234. PMID 8799183 DOI: 10.1073/Pnas.93.17.9229  0.387
1996 Orioli D, Henkemeyer M, Lemke G, Klein R, Pawson T. Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. The Embo Journal. 15: 6035-6049. DOI: 10.1002/J.1460-2075.1996.Tb00992.X  0.381
1995 Weinstein DE, Burrola PG, Lemke G. Premature Schwann cell differentiation and hypermyelination in mice expressing a targeted antagonist of the POU transcription factor SCIP. Molecular and Cellular Neuroscience. 6: 212-229. PMID 7496628 DOI: 10.1006/Mcne.1995.1018  0.393
1995 Gassmann M, Casagranda F, Orioli D, Simon H, Lai C, Klein R, Lemke G. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature. 378: 390-4. PMID 7477376 DOI: 10.1038/378390a0  0.365
1994 Plantinga LC, Schrama LH, Eggen BJ, Gispen WH, Verhaagen J, Lemke G. B-50/GAP-43 mRNA expression in cultured primary Schwann cells is regulated by cyclic AMP. Neuroreport. 5: 2465-8. PMID 7696581 DOI: 10.1097/00001756-199412000-00015  0.31
1994 Messing A, Behringer R, Wrabetz L, Hammang J, Lemke G, Palmiter R, Brinster R. Hypomyelinating peripheral neuropathies and schwannomas in transgenic mice expressing SV40 T-antigen The Journal of Neuroscience. 14: 3533-3539. DOI: 10.1523/Jneurosci.14-06-03533.1994  0.338
1993 Lemke G. Transcriptional regulation of the development of neurons and glia. Current Opinion in Neurobiology. 3: 703-708. PMID 8260818 DOI: 10.1016/0959-4388(93)90141-K  0.313
1993 Monuki ES, Kuhn R, Lemke G. Cell-specific action and mutable structure of a transcription factor effector domain. Proceedings of the National Academy of Sciences of the United States of America. 90: 9978-82. PMID 8234344 DOI: 10.1073/pnas.90.21.9978  0.607
1993 Monuki ES, Kuhn R, Lemke G. Repression of the myelin P0 gene by the POU transcription factor SCIP. Mechanisms of Development. 42: 15-32. PMID 7690239 DOI: 10.1016/0925-4773(93)90095-F  0.623
1993 Lemke G. The molecular genetics of myelination: an update. Glia. 7: 263-271. PMID 7686535 DOI: 10.1002/Glia.440070402  0.387
1993 Bögler O, Entwistle A, Kuhn R, Monuki E, Lemke G, Noble M. Single cell analysis of the expression of a nuclear protein, SCIP, by fluorescent immunohistochemistry visualized with confocal microscopy The Histochemical Journal. 25: 746-761. PMID 7506703 DOI: 10.1007/Bf00211770  0.607
1992 Giese KP, Martini R, Lemke G, Soriano P, Schachner M. Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons. Cell. 71: 565-76. PMID 1384988 DOI: 10.1016/0092-8674(92)90591-Y  0.387
1992 Messing A, Behringer RR, Hammang JP, Palmiter RD, Brinster RL, Lemke G. P0 promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice. Neuron. 8: 507-20. PMID 1372510 DOI: 10.1016/0896-6273(92)90279-M  0.388
1991 Lai C, Lemke G. An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron. 6: 691-704. PMID 2025425 DOI: 10.1016/0896-6273(91)90167-X  0.353
1991 Collarini EJ, Pringle N, Mudhar H, Stevens G, Kuhn R, Monuki ES, Lemke G, Richardson WD. Growth factors and transcription factors in oligodendrocyte development. Journal of Cell Science. Supplement. 15: 117-23. PMID 1668594 DOI: 10.1242/Jcs.1991.Supplement_15.16  0.63
1991 Lemke G, Kuhn R, Monuki ES, Weinmaster G. Expression and activity of the transcription factor SCIP during glial differentiation and myelination. Annals of the New York Academy of Sciences. 633: 189-95. PMID 1665030 DOI: 10.1111/J.1749-6632.1991.Tb15609.X  0.617
1991 Kuhn R, Monuki ES, Lemke G. The gene encoding the transcription factor SCIP has features of an expressed retroposon. Molecular and Cellular Biology. 11: 4642-50. PMID 1652060 DOI: 10.1128/Mcb.11.9.4642  0.635
1991 Nave K, Lemke G. Induction of the myelin proteolipid protein (PLP) gene in C6 glioblastoma cells: functional analysis of the PLP promotor The Journal of Neuroscience. 11: 3060-3069. DOI: 10.1523/Jneurosci.11-10-03060.1991  0.534
1991 Spreyer P, Kuhn G, Hanemann CO, Gillen C, Schaal H, Kuhn R, Lemke G, Müller HW. Axon-regulated expression of a Schwann cell transcript that is homologous to a 'growth arrest-specific' gene. The Embo Journal. 10: 3661-3668. DOI: 10.1002/J.1460-2075.1991.Tb04933.X  0.341
1990 Lemke G, Kuhn R, Monuki ES, Weinmaster G. Transcriptional controls underlying Schwann cell differentiation and myelination. Annals of the New York Academy of Sciences. 605: 248-53. PMID 2176442 DOI: 10.1111/J.1749-6632.1990.Tb42397.X  0.623
1990 Monuki ES, Kuhn R, Weinmaster G, Trapp BD, Lemke G. Expression and activity of the POU transcription factor SCIP. Science (New York, N.Y.). 249: 1300-3. PMID 1975954 DOI: 10.1126/Science.1975954  0.654
1990 Kuhn R, Pravtcheva D, Ruddle F, Lemke G. The gene encoding peripheral myelin protein zero is located on mouse chromosome 1 The Journal of Neuroscience. 10: 205-209. DOI: 10.1523/Jneurosci.10-01-00205.1990  0.304
1990 Weinmaster G, Lemke G. Cell-specific cyclic AMP-mediated induction of the PDGF receptor. The Embo Journal. 9: 915-920. DOI: 10.1002/J.1460-2075.1990.Tb08189.X  0.347
1989 Monuki ES, Weinmaster G, Kuhn R, Lemke G. SCIP: a glial POU domain gene regulated by cyclic AMP. Neuron. 3: 783-93. PMID 2561978 DOI: 10.1016/0896-6273(89)90247-X  0.643
1989 Messing A, Behrinqer RR, Hammang JP, Lemke G, Brinster RL, Palmiter RD. SCHWANN-CEIL-SPECIFIC GENE EXPRESSION IN TRANSGENIC MICE Journal of Neuropathology and Experimental Neurology. 48: 347. DOI: 10.1097/00005072-198905000-00144  0.304
1988 Lemke G, Lamar E, Patterson J. Isolation and analysis of the gene encoding peripheral myelin protein zero Neuron. 1: 73-83. PMID 2483091 DOI: 10.1016/0896-6273(88)90211-5  0.327
1986 Lemke G. Molecular biology of the major myelin genes Trends in Neurosciences. 9: 266-270. DOI: 10.1016/0166-2236(86)90076-7  0.341
1985 Lemke G, Axel R. Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin. Cell. 40: 501-8. PMID 2578885 DOI: 10.1016/0092-8674(85)90198-9  0.57
Low-probability matches (unlikely to be authored by this person)
2007 Kadi L, Burnier L, Sugamele R, Carmeliet P, Lemke G, Earp HS, Matsushima GK, Schapira M, Angelillo-Scherrer A. Targeted Disruption of GAS6-Mertk Pathway Leads to Defects in Physiological Clearance of Expelled Nuclei from Erythroblasts by Bone Marrow Macrophages. Blood. 110: 1708-1708. DOI: 10.1182/Blood.V110.11.1708.1708  0.299
2003 Zhu D, Kennerson M, Merory J, Chrast R, Verheijen M, Lemke G, Nicholson G. Refined localization of dominant intermediate Charcot-Marie-Tooth neuropathy and exclusion of seven known candidate genes in the region. Neurogenetics. 4: 179-83. PMID 12761657 DOI: 10.1007/s10048-003-0147-y  0.299
2020 Lemke G, Silverman GJ. Blood clots and TAM receptor signalling in COVID-19 pathogenesis. Nature Reviews Immunology. 20: 395-396. PMID 32488201 DOI: 10.1038/S41577-020-0354-X  0.295
2008 Pierce A, Bliesner B, Xu M, Nielsen-Preiss S, Lemke G, Tobet S, Wierman ME. Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. Molecular Endocrinology (Baltimore, Md.). 22: 2481-95. PMID 18787040 DOI: 10.1210/Me.2008-0169  0.294
2004 Chrast R, Verheijen MHG, Lemke G. Complement factors in adult peripheral nerve: a potential role in energy metabolism. Neurochemistry International. 45: 353-359. PMID 15145549 DOI: 10.1016/J.Neuint.2003.09.011  0.293
2007 Roth C, Rothlin C, Riou S, Raulet DH, Lemke G. Stromal-cell regulation of natural killer cell differentiation. Journal of Molecular Medicine (Berlin, Germany). 85: 1047-56. PMID 17426948 DOI: 10.1007/S00109-007-0195-0  0.293
2013 Carrera Silva EA, Chan PY, Joannas L, Errasti AE, Gagliani N, Bosurgi L, Jabbour M, Perry A, Smith-Chakmakova F, Mucida D, Cheroutre H, Burstyn-Cohen T, Leighton JA, Lemke G, Ghosh S, et al. T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response. Immunity. 39: 160-70. PMID 23850380 DOI: 10.1016/J.Immuni.2013.06.010  0.291
2014 Lew ED, Oh J, Burrola PG, Lax I, Zagórska A, Través PG, Schlessinger J, Lemke G. Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities. Elife. 3. PMID 25265470 DOI: 10.7554/Elife.03385  0.289
1988 Lemke G. Unwrapping the genes of myelin. Neuron. 1: 535-543. PMID 2483101 DOI: 10.1016/0896-6273(88)90103-1  0.286
2005 Angelillo-Scherrer A, Burnier L, Flores N, Savi P, DeMol M, Schaeffer P, Herbert JM, Lemke G, Goff SP, Matsushima GK, Earp HS, Vesin C, Hoylaerts MF, Plaisance S, Collen D, et al. Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy. The Journal of Clinical Investigation. 115: 237-46. PMID 15650770 DOI: 10.1172/Jci22079  0.284
2002 Stefansson H, Sigurdsson E, Steinthorsdottir V, Bjornsdottir S, Sigmundsson T, Ghosh S, Brynjolfsson J, Gunnarsdottir S, Ivarsson O, Chou TT, Hjaltason O, Birgisdottir B, Jonsson H, Gudnadottir VG, Gudmundsdottir E, ... ... Lemke G, et al. Neuregulin 1 and susceptibility to schizophrenia. American Journal of Human Genetics. 71: 877-92. PMID 12145742 DOI: 10.1086/342734  0.283
1997 Lemke G. A coherent nomenclature for Eph receptors and their ligands. Molecular and Cellular Neuroscience. 9: 331-333. PMID 9361271 DOI: 10.1006/Mcne.1997.0630  0.281
1984 Lemke GE, Brockes JP. Identification and purification of glial growth factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 75-83. PMID 6693948 DOI: 10.1523/Jneurosci.04-01-00075.1984  0.279
1994 Scherer SS, Wang DY, Kuhn R, Lemke G, Wrabetz L, Kamholz J. Axons regulate Schwann cell expression of the POU transcription factor SCIP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1930-42. PMID 8158248 DOI: 10.1523/Jneurosci.14-04-01930.1994  0.279
2015 Lemke G, Lew ED. A ligand for ALK. Science Signaling. 8: fs2. PMID 25605971 DOI: 10.1126/Scisignal.Aaa5566  0.273
1995 Lemke G, Matus A. Neuronal and glial cell biology Current Opinion in Neurobiology. 5: 547-550. DOI: 10.1016/0959-4388(95)80057-3  0.271
2016 Beermann S, Waterborg C, Bennink M, Lemke G, Koenders M, Loo Fvd. A1.05 The mer tyrosine kinase receptor plays a protective role in joint inflammation by mediating efferocytosis Annals of the Rheumatic Diseases. 75. DOI: 10.1136/Annrheumdis-2016-209124.5  0.271
2017 Waterborg CEJ, Través PG, Beermann S, Koenders MI, Lemke G, Loo FAJvd. 03.05 The tam receptors axl and mer play a protective role in a temporal and spatial manner in inflammatory arthritis Annals of the Rheumatic Diseases. 76. DOI: 10.1136/Annrheumdis-2016-211049.5  0.266
2011 Vacik T, Lemke G. Dominant-negative isoforms of Tcf/Lef proteins in development and disease. Cell Cycle. 10: 4199-4200. PMID 22157225 DOI: 10.4161/Cc.10.24.18465  0.263
1993 Polvi A, Armstrong E, Lai G, Lemke G, Huebner K, Spritz RA, Guida LC, Nicholls RD, Alitalo K. The human TYROS gene and pseudogene are located in chromosome 15q14-q25 Gene. 134: 289-293. PMID 8262388 DOI: 10.1016/0378-1119(93)90109-G  0.259
2014 Hurtado B, Burstyn-Cohen T, Escolar G, Lemke G, Frutos PGd. C0490: Role of Platelet Protein S in Primary Hemostasis in Mice Thrombosis Research. 133. DOI: 10.1016/S0049-3848(14)50098-9  0.258
2007 Burnier L, Sugamele R, Le Roy D, Roger T, Fumeaux T, Chanson M, Borgel D, Lemke G, Matsushima GK, Earp HS, Carmeliet P, Schapira M, Feihl F, Calandra T, Angelillo-Scherrer A. Gas6 and Its Receptors Are Implicated in Sepsis as Modulators of Innate Immunity. Blood. 110: 2409-2409. DOI: 10.1182/Blood.V110.11.2409.2409  0.256
2017 Kurowska-Stolarska M, Alivernini S, Melchor EG, Elmesmari A, Tolusso B, Tange C, Petricca L, Gilchrist DS, Di Sante G, Keijzer C, Stewart L, Di Mario C, Morrison V, Brewer JM, Porter D, ... ... Lemke G, et al. MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. Nature Communications. 8: 15877. PMID 28639625 DOI: 10.1038/ncomms15877  0.256
1999 Syroid DE, Zorick TS, Arbet-Engels C, Kilpatrick TJ, Eckhart W, Lemke G. A role for insulin-like growth factor-I in the regulation of Schwann cell survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2059-68. PMID 10066259  0.254
2012 Slavotinek AM, Chao R, Vacik T, Yahyavi M, Abouzeid H, Bardakjian T, Schneider A, Shaw G, Sherr EH, Lemke G, Youssef M, Schorderet DF. VAX1 mutation associated with microphthalmia, corpus callosum agenesis, and orofacial clefting: the first description of a VAX1 phenotype in humans. Human Mutation. 33: 364-8. PMID 22095910 DOI: 10.1002/Humu.21658  0.249
1988 Trapp BD, Hauer P, Lemke G. Axonal regulation of myelin protein mRNA levels in actively myelinating Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 3515-21. PMID 3171688  0.249
2011 Budagian V, Bulanova E, Orinska Z, Duitman E, Brandt K, Ludwig A, Hartmann D, Lemke G, Saftig P, Bulfone-Paus S. Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum (Molecular and Cellular Biology (2005) 25, 21, (9324-9339)) Molecular and Cellular Biology. 31: 1330. DOI: 10.1128/Mcb.05019-11  0.248
2015 Fuhs SR, Meisenhelder J, Aslanian A, Ma L, Zagorska A, Stankova M, Binnie A, Al-Obeidi F, Mauger J, Lemke G, Yates JR, Hunter T. Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation. Cell. 162: 198-210. PMID 26140597 DOI: 10.1016/J.Cell.2015.05.046  0.244
2020 Nicolás-Ávila JA, Lechuga-Vieco AV, Esteban-Martínez L, Sánchez-Díaz M, Díaz-García E, Santiago DJ, Rubio-Ponce A, Li JL, Balachander A, Quintana JA, Martínez-de-Mena R, Castejón-Vega B, Pun-García A, Través PG, Bonzón-Kulichenko E, ... ... Lemke G, et al. A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart. Cell. PMID 32937105 DOI: 10.1016/J.Cell.2020.08.031  0.238
1996 Lemke G. Neuregulins in Development Molecular and Cellular Neuroscience. 7: 247-262. PMID 8793861 DOI: 10.1006/Mcne.1996.0019  0.237
1981 Brockes JP, Fryxell KJ, Lemke GE. Studies on cultured Schwann cells: the induction of myelin synthesis, and the control of their proliferation by a new growth factor. The Journal of Experimental Biology. 95: 215-30. PMID 7038023  0.236
2014 Lew ED, Oh J, Burrola PG, Lax I, Zagórska A, Través PG, Schlessinger J, Lemke G. Author response: Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities Elife. DOI: 10.7554/Elife.03385.018  0.23
1998 Zhao JJ, Lemke G. Rules for ribozymes Molecular and Cellular Neurosciences. 11: 92-97. PMID 9608536 DOI: 10.1006/mcne.1998.0669  0.229
2005 Budagian V, Bulanova E, Orinska Z, Duitman E, Brandt K, Ludwig A, Hartmann D, Lemke G, Saftig P, Bulfone-Paus S. Soluble Axl Is Generated by ADAM10-Dependent Cleavage and Associates with Gas6 in Mouse Serum Molecular and Cellular Biology. 25: 9324-9339. PMID 16227584 DOI: 10.1128/Mcb.25.21.9324-9339.2005  0.226
2017 Waterborg CE, Beermann S, Rothlin CV, Koenders MI, Bennink MB, Kraan PMvd, Lent PLv, Hoogen FHvd, Lemke G, Loo FAvd. 03.06 Mer-mediated efferocytosis tempers arthritis by preventing neutrophil littering in the joint Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2016-211049.6  0.189
1993 Lemke G. Recitative and aria Nature. 362: 291-292. PMID 8455712 DOI: 10.1038/362291A0  0.178
1980 Brockes JP, Lemke GE, Balzer DR. Purification and preliminary characterization of a glial growth factor from the bovine pituitary. The Journal of Biological Chemistry. 255: 8374-7. PMID 7410367  0.178
1995 Lemke G, Walsh F. About this journal Molecular and Cellular Neurosciences. 6: 1. DOI: 10.1006/Mcne.1995.1001  0.176
2023 Happonen KE, Burrola PG, Lemke G. Regulation of brain endothelial cell physiology by the TAM receptor tyrosine kinase Mer. Communications Biology. 6: 916. PMID 37673933 DOI: 10.1038/s42003-023-05287-y  0.169
2008 Lemke G. Isolation and analysis of the gene encoding peripheral myelin protein zero. Neuron. 60: 403. PMID 18995810 DOI: 10.1016/j.neuron.2008.10.034  0.159
1987 Webster HF, Lamperth L, Favilla JT, Lemke G, Tesin D, Manuelidis L. Use of a biotinylated probe and in situ hybridization for light and electron microscopic localization of Po mRNA in myelin-forming Schwann cells. Histochemistry. 86: 441-4. PMID 3583818 DOI: 10.1007/Bf00500614  0.146
1996 Lemke G. Unwrapping myelination. Nature. 383: 395-6. PMID 8837768 DOI: 10.1038/383395a0  0.138
1983 Lemke GE, Brockes JP. Glial growth factor: a mitogenic polypeptide of the brain and pituitary. Federation Proceedings. 42: 2627-9. PMID 6852276  0.13
1998 Lemke G, Barde YA. Neuronal and glial cell biology. Current Opinion in Neurobiology. 8: 567-569. PMID 9811626 DOI: 10.1016/S0959-4388(98)80081-0  0.128
2023 Chen D, Varanasi SK, Hara T, Traina K, Sun M, McDonald B, Farsakoglu Y, Clanton J, Xu S, Garcia-Rivera L, Mann TH, Du V, Chung HK, Xu Z, Tripple V, ... ... Lemke G, et al. CTLA-4 blockade induces CD4 T cell IFNγ-driven microglial phagocytosis and anti-tumor function in glioblastoma. Immunity. PMID 37572655 DOI: 10.1016/j.immuni.2023.07.015  0.124
2024 Lemke G. Roger Guillemin (1924-2024), neuroscientist who showed how the brain controls hormones. Nature. 627: 266. PMID 38459135 DOI: 10.1038/d41586-024-00714-4  0.12
2020 Zagórska A, Través PG, Jiménez-García L, Strickland JD, Oh J, Tapia FJ, Mayoral R, Burrola P, Copple BL, Lemke G. Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer. Life Science Alliance. 3. PMID 32571802 DOI: 10.26508/lsa.202000694  0.12
2022 Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, ... ... Lemke G, et al. Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483. PMID 36327895 DOI: 10.1016/j.neuron.2022.10.020  0.086
2002 Lemke G, Walsh F. Molecular and cellular neuroscience: Editorial evolution Molecular and Cellular Neuroscience. 20: 1. DOI: 10.1006/mcne.2002.1154  0.079
2011 Budagian V, Bulanova E, Orinska Z, Duitman E, Brandt K, Ludwig A, Hartmann D, Lemke G, Saftig P, Bulfone-Paus S. Retraction. Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum. Molecular and Cellular Biology. 31: 1330. PMID 21350113 DOI: 10.1128/MCB.05019-11  0.073
1990 Lemke G. Mitogen signal. Nature. 348: 201. PMID 2172838 DOI: 10.1038/348201b0  0.052
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