Karen Horsburgh - Publications

Neuroscience University of Edinburgh, Edinburgh, Scotland, United Kingdom 
Cerebral metabolism, pathology

63/130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJ, Washida K, Okamoto Y, Thomas AJ, Polvikoski TM, Allan LM, Oakley AE, O'Brien JT, Horsburgh K, et al. Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. Brain : a Journal of Neurology. PMID 26667280 DOI: 10.1093/brain/awv328  0.32
2015 Kitamura A, Saito S, Maki T, Oishi N, Ayaki T, Hattori Y, Yamamoto Y, Urushitani M, Kalaria RN, Fukuyama H, Horsburgh K, Takahashi R, Ihara M. Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661170 DOI: 10.1177/0271678X15606717  0.32
2015 Holland PR, Searcy JL, Salvadores N, Scullion G, Chen G, Lawson G, Scott F, Bastin ME, Ihara M, Kalaria R, Wood ER, Smith C, Wardlaw JM, Horsburgh K. Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 1005-14. PMID 25669904 DOI: 10.1038/jcbfm.2015.12  0.32
2015 Holland PR, Pannozzo MA, Bastin ME, McNeilly AD, Ferguson KJ, Caughey S, Jansen MA, Merrifield GD, Marshall I, Mullins JJ, Wardlaw JM, Sutherland C, Horsburgh K. Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 188-92. PMID 25407269 DOI: 10.1038/jcbfm.2014.201  0.32
2014 Tsenkina Y, Ruzov A, Gliddon C, Horsburgh K, De Sousa PA. White matter tract and glial-associated changes in 5-hydroxymethylcytosine following chronic cerebral hypoperfusion. Brain Research. 1592: 82-100. PMID 25305569 DOI: 10.1016/j.brainres.2014.09.060  0.32
2014 Searcy JL, Le Bihan T, Salvadores N, McCulloch J, Horsburgh K. Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice. Plos One. 9: e89970. PMID 24587158 DOI: 10.1371/journal.pone.0089970  0.32
2014 McQueen J, Reimer MM, Holland PR, Manso Y, McLaughlin M, Fowler JH, Horsburgh K. Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion. Plos One. 9: e87227. PMID 24498301 DOI: 10.1371/journal.pone.0087227  0.32
2013 Pannozzo MA, Holland PR, Scullion G, Talbot R, Mullins JJ, Horsburgh K. Controlled hypertension induces cerebrovascular and gene alterations in Cyp1a1-Ren2 transgenic rats. Journal of the American Society of Hypertension : Jash. 7: 411-9. PMID 24119481 DOI: 10.1016/j.jash.2013.07.011  0.32
2012 Ferrington L, Palmer LE, Love S, Horsburgh KJ, Kelly PA, Kehoe PG. Angiotensin II-inhibition: effect on Alzheimer's pathology in the aged triple transgenic mouse. American Journal of Translational Research. 4: 151-64. PMID 22611468  0.32
2012 Martel MA, Ryan TJ, Bell KF, Fowler JH, McMahon A, Al-Mubarak B, Komiyama NH, Horsburgh K, Kind PC, Grant SG, Wyllie DJ, Hardingham GE. The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults. Neuron. 74: 543-56. PMID 22578505 DOI: 10.1016/j.neuron.2012.03.021  0.32
2012 James R, Searcy JL, Le Bihan T, Martin SF, Gliddon CM, Povey J, Deighton RF, Kerr LE, McCulloch J, Horsburgh K. Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 164-76. PMID 21878944 DOI: 10.1038/jcbfm.2011.120  0.32
2011 Reimer MM, McQueen J, Searcy L, Scullion G, Zonta B, Desmazieres A, Holland PR, Smith J, Gliddon C, Wood ER, Herzyk P, Brophy PJ, McCulloch J, Horsburgh K. Rapid disruption of axon-glial integrity in response to mild cerebral hypoperfusion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 18185-94. PMID 22159130 DOI: 10.1523/JNEUROSCI.4936-11.2011  0.32
2011 Bell KF, Fowler JH, Al-Mubarak B, Horsburgh K, Hardingham GE. Activation of Nrf2-regulated glutathione pathway genes by ischemic preconditioning. Oxidative Medicine and Cellular Longevity. 2011: 689524. PMID 21904646 DOI: 10.1155/2011/689524  0.32
2011 Horsburgh K, Reimer MM, Holland P, Chen G, Scullion G, Fowler JH. Axon-glial disruption: the link between vascular disease and Alzheimer's disease? Biochemical Society Transactions. 39: 881-5. PMID 21787317 DOI: 10.1042/BST0390881  0.32
2011 Comley LH, Fuller HR, Wishart TM, Mutsaers CA, Thomson D, Wright AK, Ribchester RR, Morris GE, Parson SH, Horsburgh K, Gillingwater TH. ApoE isoform-specific regulation of regeneration in the peripheral nervous system. Human Molecular Genetics. 20: 2406-21. PMID 21478199 DOI: 10.1093/hmg/ddr147  0.32
2011 Ferrington L, Miners JS, Palmer LE, Bond SM, Povey JE, Kelly PA, Love S, Horsburgh KJ, Kehoe PG. Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease. American Journal of Translational Research. 3: 197-208. PMID 21416061  0.32
2011 Holland PR, Bastin ME, Jansen MA, Merrifield GD, Coltman RB, Scott F, Nowers H, Khallout K, Marshall I, Wardlaw JM, Deary IJ, McCulloch J, Horsburgh K. MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice. Neurobiology of Aging. 32: 2325.e1-6. PMID 21194797 DOI: 10.1016/j.neurobiolaging.2010.11.009  0.32
2011 Bell KF, Al-Mubarak B, Fowler JH, Baxter PS, Gupta K, Tsujita T, Chowdhry S, Patani R, Chandran S, Horsburgh K, Hayes JD, Hardingham GE. Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 108: E1-2; author reply E. PMID 21177433 DOI: 10.1073/pnas.1015229108  0.32
2011 Coltman R, Spain A, Tsenkina Y, Fowler JH, Smith J, Scullion G, Allerhand M, Scott F, Kalaria RN, Ihara M, Daumas S, Deary IJ, Wood E, McCulloch J, Horsburgh K. Selective white matter pathology induces a specific impairment in spatial working memory. Neurobiology of Aging. 32: 2324.e7-12. PMID 20961660 DOI: 10.1016/j.neurobiolaging.2010.09.005  0.32
2010 Spain A, Daumas S, Lifshitz J, Rhodes J, Andrews PJ, Horsburgh K, Fowler JH. Mild fluid percussion injury in mice produces evolving selective axonal pathology and cognitive deficits relevant to human brain injury. Journal of Neurotrauma. 27: 1429-38. PMID 20528171 DOI: 10.1089/neu.2010.1288  0.32
2008 Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, et al. Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nature Neuroscience. 11: 476-87. PMID 18344994 DOI: 10.1038/nn2071  0.32
2007 Lai M, Horsburgh K, Bae SE, Carter RN, Stenvers DJ, Fowler JH, Yau JL, Gomez-Sanchez CE, Holmes MC, Kenyon CJ, Seckl JR, Macleod MR. Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia. The European Journal of Neuroscience. 25: 1832-42. PMID 17432969 DOI: 10.1111/j.1460-9568.2007.05427.x  0.32
2007 Magnoni S, Baker A, Thomson S, Jordan G, George SJ, McColl BW, McCulloch J, Horsburgh K. Neuroprotective effect of adenoviral-mediated gene transfer of TIMP-1 and -2 in ischemic brain injury. Gene Therapy. 14: 621-5. PMID 17235293 DOI: 10.1038/sj.gt.3302894  0.32
2007 McColl BW, McGregor AL, Wong A, Harris JD, Amalfitano A, Magnoni S, Baker AH, Dickson G, Horsburgh K. APOE epsilon3 gene transfer attenuates brain damage after experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 477-87. PMID 16804548 DOI: 10.1038/sj.jcbfm.9600361  0.32
2007 Macleod M, Horsburgh K, Bae SE, Carter R, Stenvers D, Fowler J, Yau J, Gomez-Sanchez C, Holmes M, Kenyon C, Seckl J, Lai M. Neuroprotective effects of increased forebrain mineralocorticoid receptor expression Journal of Cerebral Blood Flow and Metabolism. 27: BP07-01M.  0.32
2007 Horsburgh K, Wong A, Hodges H. Apolipoprotein has a marked effect on stem cell survival, migration and differentiation in a model of neuronal injury Journal of Cerebral Blood Flow and Metabolism. 27: BP27-01H.  0.32
2005 Wong AM, Hodges H, Horsburgh K. Neural stem cell grafts reduce the extent of neuronal damage in a mouse model of global ischaemia. Brain Research. 1063: 140-50. PMID 16289485 DOI: 10.1016/j.brainres.2005.09.049  0.32
2005 Jordan GR, McCulloch J, Shahid M, Hill DR, Henry B, Horsburgh K. Regionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography. Neuropharmacology. 49: 254-64. PMID 15993447 DOI: 10.1016/j.neuropharm.2005.03.011  0.32
2004 Magnoni S, Baker A, George SJ, Duncan WC, Kerr LE, McCulloch J, Horsburgh K. Differential alterations in the expression and activity of matrix metalloproteinases 2 and 9 after transient cerebral ischemia in mice. Neurobiology of Disease. 17: 188-97. PMID 15474357 DOI: 10.1016/j.nbd.2004.07.020  0.32
2004 Carswell HV, Macrae IM, Gallagher L, Harrop E, Horsburgh KJ. Neuroprotection by a selective estrogen receptor beta agonist in a mouse model of global ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1501-4. PMID 15155257 DOI: 10.1152/ajpheart.00227.2004  0.32
2004 McColl BW, Carswell HV, McCulloch J, Horsburgh K. Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice. Brain Research. 997: 15-23. PMID 14715145 DOI: 10.1016/j.brainres.2003.10.028  0.32
2004 Gillingwater TH, Haley JE, Ribchester RR, Horsburgh K. Neuroprotection after transient global cerebral ischemia in Wld(s) mutant mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 62-6. PMID 14688617 DOI: 10.1097/01.WCB.0000095798.98378.34  0.32
2003 McColl BW, Graham DI, Weir CJ, White F, Horsburgh K. Endocytic pathway alterations in human hippocampus after global ischemia and the influence of APOE genotype. The American Journal of Pathology. 162: 273-81. PMID 12507910 DOI: 10.1016/S0002-9440(10)63818-7  0.32
2002 Horsburgh K, Macrae IM, Carswell H. Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 1189-95. PMID 12368657 DOI: 10.1097/00004647-200210000-00006  0.32
2001 Kelly S, McCulloch J, Horsburgh K. Minimal ischaemic neuronal damage and HSP70 expression in MF1 strain mice following bilateral common carotid artery occlusion. Brain Research. 914: 185-95. PMID 11578611 DOI: 10.1016/S0006-8993(01)02801-3  0.32
2001 McKracken E, Graham DI, Nilsen M, Stewart J, Nicoll JA, Horsburgh K. 4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia. Brain Pathology (Zurich, Switzerland). 11: 414-21. PMID 11556686  0.32
2001 White F, Nicoll JA, Roses AD, Horsburgh K. Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion. Neurobiology of Disease. 8: 611-25. PMID 11493026 DOI: 10.1006/nbdi.2001.0401  0.32
2001 Kelly S, Bieneman A, Horsburgh K, Hughes D, Sofroniew MV, McCulloch J, Uney JB. Targeting expression of hsp70i to discrete neuronal populations using the Lmo-1 promoter: assessment of the neuroprotective effects of hsp70i in vivo and in vitro. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 972-81. PMID 11487733 DOI: 10.1097/00004647-200108000-00010  0.32
2001 White F, Nicoll JA, Horsburgh K. Alterations in ApoE and ApoJ in relation to degeneration and regeneration in a mouse model of entorhinal cortex lesion. Experimental Neurology. 169: 307-18. PMID 11358444 DOI: 10.1006/exnr.2001.7655  0.32
2000 Horsburgh K, McCulloch J, Nilsen M, Roses AD, Nicoll JA. Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia. The European Journal of Neuroscience. 12: 4309-17. PMID 11122341 DOI: 10.1046/j.1460-9568.2000.01339.x  0.32
2000 Horsburgh K, McCarron MO, White F, Nicoll JA. The role of apolipoprotein E in Alzheimer's disease, acute brain injury and cerebrovascular disease: evidence of common mechanisms and utility of animal models. Neurobiology of Aging. 21: 245-55. PMID 10867209 DOI: 10.1016/S0197-4580(00)00097-X  0.32
2000 Horsburgh K, Cole GM, Yang F, Savage MJ, Greenberg BD, Gentleman SM, Graham DI, Nicoll JA. beta-amyloid (Abeta)42(43), abeta42, abeta40 and apoE immunostaining of plaques in fatal head injury. Neuropathology and Applied Neurobiology. 26: 124-32. PMID 10840275 DOI: 10.1046/j.1365-2990.2000.026002124.x  0.32
2000 Horsburgh K, McCulloch J, Nilsen M, McCracken E, Large C, Roses AD, Nicoll JA. Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 458-62. PMID 10724109 DOI: 10.1097/00004647-200003000-00003  0.32
1999 McDonald RP, Horsburgh KJ, Graham DI, Nicoll JA. Mitochondrial DNA deletions in acute brain injury. Neuroreport. 10: 1875-8. PMID 10501524  0.32
1999 Graham DI, Horsburgh K, Nicoll JA, Teasdale GM. Apolipoprotein E and the response of the brain to injury. Acta Neurochirurgica. Supplement. 73: 89-92. PMID 10494348  0.32
1999 Horsburgh K, Kelly S, McCulloch J, Higgins GA, Roses AD, Nicoll JA. Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia. Neuroreport. 10: 837-41. PMID 10208557  0.32
1999 Horsburgh K, Graham DI, Stewart J, Nicoll JA. Influence of apolipoprotein E genotype on neuronal damage and apoE immunoreactivity in human hippocampus following global ischemia. Journal of Neuropathology and Experimental Neurology. 58: 227-34. PMID 10197814  0.32
1998 Laskowitz DT, Horsburgh K, Roses AD. Apolipoprotein E and the CNS response to injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 465-71. PMID 9591838 DOI: 10.1097/00004647-199805000-00001  0.32
1997 Horsburgh K, Fitzpatrick M, Nilsen M, Nicoll JA. Marked alterations in the cellular localisation and levels of apolipoprotein E following acute subdural haematoma in rat. Brain Research. 763: 103-10. PMID 9272834 DOI: 10.1016/S0006-8993(97)00411-3  0.32
1997 Horsburgh K, Mackay KB, McCulloch J. Intracortical glutamate perfusion in vivo induces cellular alterations in specific protein kinase C isoforms and amyloid precursor protein. Experimental Neurology. 143: 207-18. PMID 9056384 DOI: 10.1006/exnr.1996.6356  0.32
1996 Horsburgh K, Nicoll JA. Selective alterations in the cellular distribution of apolipoprotein E immunoreactivity following transient cerebral ischaemia in the rat. Neuropathology and Applied Neurobiology. 22: 342-9. PMID 8875469  0.32
1996 Horsburgh K, Nicoll JAR. Selective cellular alterations in amyloid precursor protein and apolipoprotein E following transient cerebral ischaemia in the rat Alzheimer's Research. 2: 37-42.  0.32
1995 Chen X, de Silva HA, Pettenati MJ, Rao PN, St George-Hyslop P, Roses AD, Xia Y, Horsburgh K, Uéda K, Saitoh T. The human NACP/alpha-synuclein gene: chromosome assignment to 4q21.3-q22 and TaqI RFLP analysis. Genomics. 26: 425-7. PMID 7601479 DOI: 10.1016/0888-7543(95)80237-G  0.32
1993 Horsburgh K, Inglis FM, McCulloch J. Focal increases in [3H]forskolin and [3H]phorbol 12,13-dibutyrate binding in the rat brain following lesions of the medial septum. Neuroscience Letters. 151: 166-9. PMID 8506075 DOI: 10.1016/0304-3940(93)90012-A  0.32
1993 Saitoh T, Horsburgh K, Masliah E. Hyperactivation of signal transduction systems in Alzheimer's disease. Annals of the New York Academy of Sciences. 695: 34-41. PMID 8239309 DOI: 10.1111/j.1749-6632.1993.tb23023.x  0.32
1992 Buzsáki G, Hsu M, Horvath Z, Horsburgh K, Sundsmo M, Masliah E, Saitoh T. Kindling-induced changes of protein kinase C levels in hippocampus and neocortex. Epilepsy Research. Supplement. 9: 279-83; discussion 2. PMID 1337442  0.32
1991 Horsburgh K, Dewar D, Graham DI, McCulloch J. Autoradiographic imaging of [3H]phorbol 12,13-dibutyrate binding to protein kinase C in Alzheimer's disease. Journal of Neurochemistry. 56: 1121-9. PMID 2002333  0.32
1991 Horsburgh K, McCulloch J. Alterations of functional glucose use and ligand binding to second messenger systems following unilateral orbital enucleation. Brain Research. 549: 317-21. PMID 1884225 DOI: 10.1016/0006-8993(91)90474-A  0.32
1991 Horsburgh K, McCulloch J. Differential alterations of second messenger systems and cerebral glucose use following excitotoxic lesion of rat cerebral cortex. Brain Research. 563: 306-10. PMID 1723923 DOI: 10.1016/0006-8993(91)91552-C  0.32
1991 Browne SE, Horsburgh K, Dewar D, McCulloch J. D-[3H]-aspartate binding does not locate glutamate-releasing neurones in the retino-fugal projection: An autoradiographic comparison with [H]-cyclohexyladenosine binding Molecular Neuropharmacology. 1: 129-133.  0.32
1990 Dewar D, Horsburgh K, Graham DI, Brooks DN, McCulloch J. Selective alterations of high affinity [3H]forskolin binding sites in Alzheimer's disease: a quantitative autoradiographic study. Brain Research. 511: 241-8. PMID 2110494 DOI: 10.1016/0006-8993(90)90168-B  0.32
1990 Horsburgh K, Jansen I, Edvinsson L, McCulloch J. Second messenger systems: functional role in cerebrovascular smooth muscle regulation. European Journal of Pharmacology. 191: 205-11. PMID 2086238 DOI: 10.1016/0014-2999(90)94148-Q  0.32
1989 Edvinsson L, Fallgren B, Jansen I, Horsburgh K. Mechanisms of action and interaction of perivascular peptides and nonpeptides in cerebral vasoconstriction Neurotransmission and Cerebrovascular Function Vol. 1: Proceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. Ics869. 131-135.  0.32
Low-probability matches
2019 Hase Y, Polvikoski TM, Ihara M, Hase M, Zafar R, Stevenson W, Allan LM, Ennaceur A, Horsburgh K, Gallart-Palau X, Sze SK, Kalaria RN. Carotid Artery Disease in Post-Stroke Survivors and Effects of Enriched Environment on Stroke Pathology in a Mouse Model of Carotid Artery Stenosis. Neuropathology and Applied Neurobiology. PMID 30947376 DOI: 10.1111/nan.12550  0.24
2018 Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, et al. Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. Clinical Science (London, England : 1979). 132: 851-868. PMID 29712883 DOI: 10.1042/CS20171620  0.24
2017 Hase Y, Horsburgh K, Ihara M, Kalaria RN. White Matter Degeneration in Vascular and Other Ageing-Related Dementias. Journal of Neurochemistry. PMID 29210074 DOI: 10.1111/jnc.14271  0.24
2017 Duncombe J, Kitamura A, Hase Y, Ihara M, Kalaria RN, Horsburgh K. Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia. Clinical Science (London, England : 1979). 131: 2451-2468. PMID 28963120 DOI: 10.1042/CS20160727  0.24
2017 Kitamura A, Manso Y, Duncombe J, Searcy J, Koudelka J, Binnie M, Webster S, Lennen R, Jansen M, Marshall I, Ihara M, Kalaria RN, Horsburgh K. Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion. Scientific Reports. 7: 4299. PMID 28655874 DOI: 10.1038/s41598-017-04082-0  0.24
2017 Fowler JH, McQueen J, Holland PR, Manso Y, Marangoni M, Scott F, Chisholm E, Scannevin RH, Hardingham GE, Horsburgh K. Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17713105. PMID 28606007 DOI: 10.1177/0271678X17713105  0.24
2017 Hase Y, Craggs L, Hase M, Stevenson W, Slade J, Lopez D, Mehta R, Chen A, Liang D, Oakley A, Ihara M, Horsburgh K, Kalaria RN. Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion. Journal of Neuroinflammation. 14: 81. PMID 28399892 DOI: 10.1186/s12974-017-0850-5  0.24
2017 Hase Y, Craggs L, Hase M, Stevenson W, Slade J, Chen A, Liang D, Ennaceur A, Oakley A, Ihara M, Horsburgh K, Kalaria RN. The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17694904. PMID 28273725 DOI: 10.1177/0271678X17694904  0.24
2018 Sigfridsson E, Marangoni M, Johnson JA, Hardingham GE, Fowler JH, Horsburgh K. Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion. Scientific Reports. 8: 12552. PMID 30135571 DOI: 10.1038/s41598-018-30675-4  0.2
2017 Manso Y, Holland PR, Kitamura A, Szymkowiak S, Duncombe J, Hennessy E, Searcy JL, Marangoni M, Randall AD, Brown JT, McColl BW, Horsburgh K. Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease. Glia. PMID 28722234 DOI: 10.1002/glia.23190  0.12
2017 Salvadores N, Searcy JL, Holland PR, Horsburgh K. Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and hemorrhages in Tg-SwDI mice. Clinical Science (London, England : 1979). PMID 28667120 DOI: 10.1042/CS20170962  0.12
2016 Duncombe J, Lennen RJ, Jansen MA, Marshall I, Wardlaw JM, Horsburgh K. Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis. Neuropathology and Applied Neurobiology. PMID 28039950 DOI: 10.1111/nan.12375  0.08
2018 Jones FE, Murray LS, McNeilly S, Dean A, Aman A, Lu Y, Nikolova N, Malomgré R, Horsburgh K, Holmes WM, Kadler KE, Van Agtmael T. 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics. PMID 30351356 DOI: 10.1093/hmg/ddy369  0.01
2017 Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, et al. Recent progress in translational research on neurovascular and neurodegenerative disorders. Restorative Neurology and Neuroscience. PMID 28059802 DOI: 10.3233/RNN-160690  0.01
2016 Wardlaw JM, Horsburgh K. Small vessels, dementia and chronic diseases-molecular mechanisms and pathophysiology. Clinical Science (London, England : 1979). 130: 1875-9. PMID 27660310 DOI: 10.1042/CS20160376  0.01
2015 Greig K, Boocock J, Prost S, Horsburgh KA, Jacomb C, Walter R, Matisoo-Smith E. Complete Mitochondrial Genomes of New Zealand's First Dogs. Plos One. 10: e0138536. PMID 26444283 DOI: 10.1371/journal.pone.0138536  0.01
2015 Haigh ID, Wadey MP, Gallop SL, Loehr H, Nicholls RJ, Horsburgh K, Brown JM, Bradshaw E. A user-friendly database of coastal flooding in the United Kingdom from 1915-2014. Scientific Data. 2: 150021. PMID 25984352 DOI: 10.1038/sdata.2015.21  0.01
2015 Horsburgh KA. Molecular anthropology: The judicial use of genetic data in archaeology Journal of Archaeological Science. 56: 141-145. DOI: 10.1016/j.jas.2015.02.033  0.01
2015 Breivik Ø, Swail V, Babanin AV, Horsburgh K. The international workshop on wave hindcasting and forecasting and the coastal hazards symposium Ocean Dynamics. 65: 761-771. DOI: 10.1007/s10236-015-0827-9  0.01
2014 Maskell J, Horsburgh K, Lewis M, Bates P. Investigating river-surge interaction in idealised estuaries Journal of Coastal Research. 30: 248-259. DOI: 10.2112/JCOASTRES-D-12-00221.1  0.01
2014 Yasuda T, Nakajo S, Kim S, Mase H, Mori N, Horsburgh K. Evaluation of future storm surge risk in East Asia based on state-of-the-art climate change projection Coastal Engineering. 83: 65-71. DOI: 10.1016/j.coastaleng.2013.10.003  0.01
2014 Lewis M, Horsburgh K, Bates P. Bay of Bengal cyclone extreme water level estimate uncertainty Natural Hazards. 72: 983-996. DOI: 10.1007/s11069-014-1046-2  0.01
2013 Horsburgh KA, Prost S, Gosling A, Stanton JA, Rand C, Matisoo-Smith EA. The genetic diversity of the Nguni breed of African Cattle (Bos spp.): complete mitochondrial genomes of haplogroup T1. Plos One. 8: e71956. PMID 23977187 DOI: 10.1371/journal.pone.0071956  0.01
2013 Batstone C, Lawless M, Tawn J, Horsburgh K, Blackman D, McMillan A, Worth D, Laeger S, Hunt T. A UK best-practice approach for extreme sea-level analysis along complex topographic coastlines Ocean Engineering. 71: 28-39. DOI: 10.1016/j.oceaneng.2013.02.003  0.01
2013 Royston S, Lawry J, Horsburgh K. A linguistic decision tree approach to predicting storm surge Fuzzy Sets and Systems. 215: 90-111. DOI: 10.1016/j.fss.2012.10.001  0.01
2013 Lewis M, Schumann G, Bates P, Horsburgh K. Understanding the variability of an extreme storm tide along a coastline Estuarine, Coastal and Shelf Science. 123: 19-25. DOI: 10.1016/j.ecss.2013.02.009  0.01
2013 Maskell J, Horsburgh K, Plater AJ. Investigating enhanced atmospheric-sea surface coupling and interactions in the Irish Sea Continental Shelf Research. 53: 30-39. DOI: 10.1016/j.csr.2012.11.018  0.01
2013 Tappin DR, Sibley A, Horsburgh K, Daubord C, Cox D, Long D. The English Channel 'tsunami' of 27 June 2011 - A probable meteorological source Weather. 68: 144-152. DOI: 10.1002/wea.2061  0.01
2013 Lewis M, Bates P, Horsburgh K, Neal J, Schumann G. A storm surge inundation model of the northern Bay of Bengal using publicly available data Quarterly Journal of the Royal Meteorological Society. 139: 358-369. DOI: 10.1002/qj.2040  0.01
2013 Smith PJ, Beven KJ, Horsburgh K. Data-based mechanistic modelling of tidally affected river reaches for flood warning purposes: An example on the River Dee, UK Quarterly Journal of the Royal Meteorological Society. 139: 340-349. DOI: 10.1002/qj.1926  0.01
2013 Wilson C, Horsburgh KJ, Williams J, Flowerdew J, Zanna L. Tide-surge adjoint modeling: A new technique to understand forecast uncertainty Journal of Geophysical Research: Oceans. 118: 5092-5108. DOI: 10.1002/jgrc.20364  0.01
2013 Orton J, Mitchell P, Klein R, Steele T, Horsburgh KA. An early date for cattle from Namaqualand, South Africa: Implications for the origins of herding in southern Africa Antiquity. 87: 108-120.  0.01
2012 Knapp M, Horsburgh KA, Prost S, Stanton JA, Buckley HR, Walter RK, Matisoo-Smith EA. Complete mitochondrial DNA genome sequences from the first New Zealanders. Proceedings of the National Academy of Sciences of the United States of America. 109: 18350-4. PMID 23091021 DOI: 10.1073/pnas.1209896109  0.01
2012 Knapp M, Clarke AC, Horsburgh KA, Matisoo-Smith EA. Setting the stage - building and working in an ancient DNA laboratory. Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. 194: 3-6. PMID 21514120 DOI: 10.1016/j.aanat.2011.03.008  0.01
2012 McMillan A, Worth D, Laeger S, Hunt T, Scott A, Becker M, Horsburgh K, Lawless M, Batstone C, Tawn J. How high is high enough? - The art of assessing extreme conditions for effective coastal management Innovative Coastal Zone Management: Sustainable Engineering For a Dynamic Coast - 7th International Coastal Management Conference. 12-21. DOI: 10.1680/iczm.57494.012  0.01
2012 Po E, Horsburgh K, Raadsma HW, Celi P. Yerba Mate (Ilex paraguarensis) as a novel feed supplement for growing lambs Small Ruminant Research. 106: 131-136. DOI: 10.1016/j.smallrumres.2012.05.016  0.01
2012 Royston SJ, Horsburgh KJ, Lawry J. Application of rule based methods to predicting storm surge Continental Shelf Research. 37: 79-91. DOI: 10.1016/j.csr.2012.02.018  0.01
2012 Pickering MD, Wells NC, Horsburgh KJ, Green JAM. The impact of future sea-level rise on the European Shelf tides Continental Shelf Research. 35: 1-15. DOI: 10.1016/j.csr.2011.11.011  0.01
2011 Lewis M, Horsburgh K, Bates P, Smith R. Quantifying the uncertainty in future coastal flood risk estimates for the U.K Journal of Coastal Research. 27: 870-881. DOI: 10.2112/JCOASTRES-D-10-00147.1  0.01
2011 Woodworth PL, Horsburgh KJ. Surge models as providers of improved inverse barometer corrections for coastal altimetry users Coastal Altimetry. 177-189. DOI: 10.1007/978-3-642-12796-0_7  0.01
2010 Howard T, Lowe J, Horsburgh K. Interpreting century-scale changes in southern north sea storm surge climate derived from coupled model simulations Journal of Climate. 23: 6234-6247. DOI: 10.1175/2010JCLI3520.1  0.01
2010 Turner JF, Iliffe JC, Ziebart MK, Wilson C, Horsburgh KJ. Interpolation of tidal levels in the coastal zone for the creation of a hydrographic datum Journal of Atmospheric and Oceanic Technology. 27: 605-613. DOI: 10.1175/2009JTECHO645.1  0.01
2010 Lowe JA, Woodworth PL, Knutson T, Mcdonald RE, Mcinnes KL, Woth K, von Storch H, Wolf J, Swail V, Bernier NB, Gulev S, Horsburgh KJ, Unnikrishnan AS, Hunter JR, Weisse R. Past and Future Changes in Extreme Sea Levels and Waves Understanding Sea-Level Rise and Variability. 326-375. DOI: 10.1002/9781444323276.ch11  0.01
2009 Flowerdew J, Horsburgh K, Mylne K. Ensemble forecasting of storm surges Marine Geodesy. 32: 91-99. DOI: 10.1080/01490410902869151  0.01
2009 Swail VR, Etala P, Dube SK, Horsburgh K. Guest editorial Natural Hazards. 51: 1-2. DOI: 10.1007/s11069-009-9422-z  0.01
2009 Scott TR, Smith PJ, Dance SL, Mason DC, Baines MJ, Nichols NK, Horsburgh KJ, Sweby PK, Lawless AS. Data assimilation for morphodynamic prediction and predictability Proceedings of the Coastal Engineering Conference. 2386-2398.  0.01
2009 Pullen T, Tozer N, Sayers P, Hawkes P, Saulter A, Flowerdew J, Horsburgh K. Use of field measurements to improve probabilistic wave overtopping forecasts Proceedings of the Coastal Engineering Conference. 3020-3031.  0.01
2008 Randon NJ, Lawry J, Horsburgh K, Cluckie ID. Fuzzy Bayesian modeling of sea-level along the east coast of Britain Ieee Transactions On Fuzzy Systems. 16: 725-738. DOI: 10.1109/TFUZZ.2008.919278  0.01
2008 Hill AE, Brown J, Fernand L, Holt J, Horsburgh KJ, Proctor R, Raine R, Turrell WR. Thermohaline circulation of shallow tidal seas Geophysical Research Letters. 35. DOI: 10.1029/2008GL033459  0.01
2008 Horsburgh KJ, Wilson C, Baptie BJ, Cooper A, Cresswell D, Musson RMW, Ottemöller L, Richardson S, Sargeant SL. Impact of a Lisbon-type tsunami on the U.K. coastline and the implications for tsunami propagation over broad continental shelves Journal of Geophysical Research: Oceans. 113. DOI: 10.1029/2007JC004425  0.01
2008 Horsburgh KA. Wild or domesticated? An ancient DNA approach to canid species identification in South Africa's Western Cape Province Journal of Archaeological Science. 35: 1474-1480. DOI: 10.1016/j.jas.2007.10.012  0.01
2007 Horsburgh KJ, Wilson C. Tide-surge interaction and its role in the distribution of surge residuals in the North Sea Journal of Geophysical Research: Oceans. 112. DOI: 10.1029/2006JC004033  0.01
2007 Butler A, Heffernan JE, Tawn JA, Flather RA, Horsburgh KJ. Extreme value analysis of decadal variations in storm surge elevations Journal of Marine Systems. 67: 189-200. DOI: 10.1016/j.jmarsys.2006.10.006  0.01
2006 Uehara K, Scourse JD, Horsburgh KJ, Lambeck K, Purcell AP. Tidal evolution of the northwest European shelf seas from the Last Glacial Maximum to the present Journal of Geophysical Research: Oceans. 111. DOI: 10.1029/2006JC003531  0.01
2006 Kobayashi S, Simpson JH, Fujiwara T, Horsburgh KJ. Tidal stirring and its impact on water column stability and property distributions in a semi-enclosed shelf sea (Seto Inland Sea, Japan) Continental Shelf Research. 26: 1295-1306. DOI: 10.1016/j.csr.2006.04.006  0.01
2004 Young EF, Brown J, Aldridge JN, Horsburgh KJ, Fernand L. Development and application of a three-dimensional baroclinic model to the study of the seasonal circulation in the Celtic Sea Continental Shelf Research. 24: 13-36. DOI: 10.1016/j.csr.2003.09.003  0.01
2003 Brown J, Carrillo L, Fernand L, Horsburgh KJ, Hill AE, Young EF, Medler KJ. Observations of the physical structure and seasonal jet-like circulation of the Celtic Sea and St. George's Channel of the Irish Sea Continental Shelf Research. 23: 533-561. DOI: 10.1016/S0278-4343(03)00008-6  0.01
2003 Horsburgh KJ, Hill AE. A three-dimensional model of density-driven circulation in the Irish Sea Journal of Physical Oceanography. 33: 343-365.  0.01
2002 Kaestle FA, Horsburgh KA. Ancient DNA in anthropology: methods, applications, and ethics. American Journal of Physical Anthropology. 92-130. PMID 12653310 DOI: 10.1002/ajpa.10179  0.01
2002 Young EF, Brown J, Horsburgh KJ, Fernand L. Three-dimensional modelling of the summer circulation in the celtic sea Proceedings of the International Conference On Estuarine and Coastal Modeling. 1-21. DOI: 10.1061/40628(268)1  0.01
2001 Brown J, Fernand L, Horsburgh KJ, Hill AE, Read JW. Paralytic shellfish poisoning on the east coast of the UK in relation to seasonal density-driven circulation Journal of Plankton Research. 23: 105-116.  0.01
2000 Horsburgh KJ, Hill AE, Brown J, Fernand L, Garvine RW, Angelico MMP. Seasonal Evolution of the cold pool gyre in the western Irish Sea Progress in Oceanography. 46: 1-58. DOI: 10.1016/S0079-6611(99)00054-3  0.01
1999 Brown J, Hill AE, Fernand L, Horsburgh KJ. Observations of a seasonal jet-like circulation at the central North Sea cold pool margin Estuarine, Coastal and Shelf Science. 48: 343-355. DOI: 10.1006/ecss.1999.0426  0.01
1998 Horsburgh KJ, Hill AE, Brown J. A summer jet in the St George's Channel of the Irish Sea Estuarine, Coastal and Shelf Science. 47: 285-294. DOI: 10.1006/ecss.1998.0354  0.01
1997 Hill AE, Horsburgh KJ, Garvine RW, Gillibrand PA, Slesser G, Turrell WR, Adams RD. Observations of a density-driven recirculation of the Scottish coastal current in the Minch Estuarine, Coastal and Shelf Science. 45: 473-484. DOI: 10.1006/ecss.1996.0198  0.01
1997 Dickey-Collas M, Brown J, Fernand L, Hill AE, Horsburgh KJ, Garvine RW. Does the western Irish Sea gyre influence the distribution of pelagic juvenile fish? Journal of Fish Biology. 51: 206-229.  0.01
1995 Wheeler G, Horsburgh K, Berlin R, John R, Ewald B, Cabaron D. Death in the desert. Australian Family Physician. 24: 2143; author reply 2. PMID 8579552  0.01
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