Eric Fliers - Publications

Affiliations: 
University of Amsterdam, Amsterdam, Netherlands 
Area:
neuro-endocrinology
Website:
http://www.amc.nl/index.cfm?pid=2729&contentitemid=134&&itemid=99

290 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Stenvers DJ, Jongejan A, Atiqi S, Vreijling JP, Limonard EJ, Endert E, Baas F, Moerland PD, Fliers E, Kalsbeek A, Bisschop PH. Diurnal rhythms in the white adipose tissue transcriptome are disturbed in obese individuals with type 2 diabetes compared with lean control individuals. Diabetologia. PMID 30737520 DOI: 10.1007/s00125-019-4813-5  1
2018 Zhang Z, Boelen A, Kalsbeek A, Fliers E. TRH Neurons and Thyroid Hormone Coordinate the Hypothalamic Response to Cold. European Thyroid Journal. 7: 279-288. PMID 30574457 DOI: 10.1159/000493976  1
2018 Zhang Z, Machado F, Zhao L, Heinen C, Foppen E, Ackermans MT, Zhou JN, Bisschop P, Boelen A, Fliers E, Kalsbeek A. Administration of thyrotropin-releasing hormone (TRH) in the hypothalamic paraventricular nucleus (PVN) of male rats mimics the metabolic cold defence response. Neuroendocrinology. PMID 30092582 DOI: 10.1159/000492785  1
2018 Heinen CA, de Vries EM, Alders M, Bikker H, Zwaveling-Soonawala N, van den Akker ELT, Bakker B, Hoorweg-Nijman G, Roelfsema F, Hennekam RC, Boelen A, van Trotsenburg ASP, Fliers E. Mutations in IRS4 are associated with central hypothyroidism. Journal of Medical Genetics. PMID 30061370 DOI: 10.1136/jmedgenet-2017-105113  0.6
2018 Ter Horst KW, Lammers NM, Trinko R, Opland DM, Figee M, Ackermans MT, Booij J, van den Munckhof P, Schuurman PR, Fliers E, Denys D, DiLeone RJ, la Fleur SE, Serlie MJ. Striatal dopamine regulates systemic glucose metabolism in humans and mice. Science Translational Medicine. 10. PMID 29794060 DOI: 10.1126/scitranslmed.aar3752  0.88
2018 van der Spek R, Fliers E, la Fleur SE, Kalsbeek A. Daily Gene Expression Rhythms in Rat White Adipose Tissue Do Not Differ Between Subcutaneous and Intra-Abdominal Depots. Frontiers in Endocrinology. 9: 206. PMID 29760682 DOI: 10.3389/fendo.2018.00206  1
2018 Heinen CA, Zhang Z, Klieverik LP, de Wit TC, Poel E, Yaqub M, Boelen A, Kalsbeek A, Bisschop PH, van Trotsenburg P, Verberne H, Booij J, Fliers E. Effects of Intravenous Thyrotropin Releasing Hormone on 18F-Fluorodeoxyglucose Uptake in Human Brown Adipose Tissue: A Randomized Controlled Trial. European Journal of Endocrinology. PMID 29724865 DOI: 10.1530/EJE-17-0966  1
2018 van der Spek AH, Surovtseva OV, Jim KK, van Oudenaren A, Brouwer MC, Vandenbroucke-Grauls CMJE, Leenen PJM, van de Beek D, Hernandez A, Fliers E, Boelen A. Regulation of Intracellular Triiodothyronine is Essential for Optimal Macrophage Function. Endocrinology. PMID 29648626 DOI: 10.1210/en.2018-00053  0.6
2018 Su Y, Foppen E, Mansur Machado FS, Fliers E, Kalsbeek A. The role of the daily feeding rhythm in the regulation of the day/night rhythm in triglyceride secretion in rats. Chronobiology International. 1-11. PMID 29446660 DOI: 10.1080/07420528.2018.1438456  1
2018 van Dijk MM, Smits I, Fliers E, Bisschop PH. Maternal thyrotropin receptor antibody concentration and the risk of fetal and neonatal thyrotoxicosis: A systematic review. Thyroid : Official Journal of the American Thyroid Association. PMID 29325496 DOI: 10.1089/thy.2017.0413  0.76
2017 Kalsbeek A, Fliers E. Preface - Part 2: Circadian and endocrine rhythms. Best Practice & Research. Clinical Endocrinology & Metabolism. 31: 519. PMID 29224664 DOI: 10.1016/j.beem.2017.11.006  1
2017 Roelfsema F, Boelen A, Kalsbeek A, Fliers E. Regulatory aspects of the human hypothalamus-pituitary-thyroid axis. Best Practice & Research. Clinical Endocrinology & Metabolism. 31: 487-503. PMID 29223283 DOI: 10.1016/j.beem.2017.09.004  1
2017 Kalsbeek A, Fliers E. Circadian and endocrine rhythms. Best Practice & Research. Clinical Endocrinology & Metabolism. 31: 443. PMID 29223279 DOI: 10.1016/j.beem.2017.11.005  1
2017 van der Spek AH, Jim KK, Karaczyn A, van Beeren HC, Ackermans MT, Darras VM, Vandenbroucke-Grauls CMJE, Hernandez A, Brouwer MC, Fliers E, van de Beek D, Boelen A. The Thyroid Hormone Inactivating Type 3 Deiodinase is Essential for Optimal Neutrophil Function - observations from 3 species. Endocrinology. PMID 29186449 DOI: 10.1210/en.2017-00666  0.88
2017 van der Spek AH, Surovtseva OV, Aan S, Tool ATJ, van de Geer A, Demir K, van Gucht ALM, van Trotsenburg ASP, van den Berg TK, Fliers E, Boelen A. Increased circulating interleukin-8 in patients with resistance to thyroid hormone receptor α. Endocrine Connections. 6: 731-740. PMID 29101248 DOI: 10.1530/EC-17-0213  0.6
2017 Versteeg RI, Schrantee A, Adriaanse SM, Unmehopa UA, Booij J, Reneman L, Fliers E, la Fleur SE, Serlie MJ. Timing of caloric intake during weight loss differentially affects striatal dopamine transporter and thalamic serotonin transporter binding. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28679529 DOI: 10.1096/fj.201601234R  0.84
2017 Versteeg RI, Stenvers DJ, Visintainer D, Linnenbank A, Tanck MW, Zwanenburg G, Smilde AK, Fliers E, Kalsbeek A, Serlie MJ, la Fleur SE, Bisschop PH. Acute Effects of Morning Light on Plasma Glucose and Triglycerides in Healthy Men and Men with Type 2 Diabetes. Journal of Biological Rhythms. 32: 130-142. PMID 28470119 DOI: 10.1177/0748730417693480  1
2017 Opperhuizen AL, Stenvers DJ, Jansen RD, Foppen E, Fliers E, Kalsbeek A. Light at night acutely impairs glucose tolerance in a time-, intensity- and wavelength-dependent manner in rats. Diabetologia. PMID 28374068 DOI: 10.1007/s00125-017-4262-y  1
2017 Zwaveling-Soonawala N, Witteveen E, Marchal JP, Klouwer F, Ikelaar N, Smets A, van Rijn R, Endert E, Fliers E, van Trotsenburg P. Early thyroxine treatment in Down syndrome and thyroid function later in life. European Journal of Endocrinology. PMID 28137734 DOI: 10.1530/EJE-16-0858  0.64
2017 Boelen A, van der Spek AH, Bloise FF, de Vries EM, Surovtseva OV, van Beeren HC, Ackermans MT, Kwakkel J, Fliers E. Tissue thyroid hormone metabolism is differentially regulated during illness in mice. The Journal of Endocrinology. PMID 28130411 DOI: 10.1530/JOE-16-0483  0.88
2017 van der Spek AH, Fliers E, Boelen A. The classic pathways of thyroid hormone metabolism. Molecular and Cellular Endocrinology. PMID 28109953 DOI: 10.1016/j.mce.2017.01.025  0.6
2017 Zhang Z, Boelen A, Bisschop PH, Kalsbeek A, Fliers E. Hypothalamic effects of thyroid hormone. Molecular and Cellular Endocrinology. PMID 28088468 DOI: 10.1016/j.mce.2017.01.018  1
2016 van der Spek AH, Fliers E, Boelen A. Thyroid hormone metabolism in innate immune cells. The Journal of Endocrinology. PMID 27852725 DOI: 10.1530/JOE-16-0462  0.6
2016 van Brussel PM, van den Bogaard B, de Weijer BA, Truijen J, Krediet PC, Janssen IM, van de Laar A, Kaasjager KA, Fliers E, Van Lieshout JJ, Serlie MJ, van den Born BH. THE BLOOD PRESSURE REDUCTION AFTER GASTRIC BYPASS SURGERY IS EXPLAINED BY A DECREASE IN CARDIAC OUTPUT. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00362.2016. PMID 27765843 DOI: 10.1152/japplphysiol.00362.2016  0.84
2016 Jan Stenvers D, van Dorp R, Foppen E, Mendoza J, Opperhuizen AL, Fliers E, Bisschop PH, Meijer JH, Kalsbeek A, Deboer T. Dim light at night disturbs the daily sleep-wake cycle in the rat. Scientific Reports. 6: 35662. PMID 27762290 DOI: 10.1038/srep35662  1
2016 Diepenbroek C, Eggels L, Ackermans MT, Fliers E, Kalsbeek A, Serlie MJ, la Fleur SE. Differential effects of hyper caloric choice diets on insulin sensitivity in rats. The Journal of Endocrinology. PMID 27754934 DOI: 10.1530/JOE-16-0265  1
2016 Versteeg RI, Koopman KE, Booij J, Ackermans MT, Unmehopa UA, Fliers E, la Fleur SE, Serlie MJ. Serotonin Transporter Binding in the Diencephalon is Reduced in Insulin Resistant Obese Humans. Neuroendocrinology. PMID 27626923 DOI: 10.1159/000450549  0.88
2016 Heinen CA, Losekoot M, Sun Y, Watson PJ, Fairall L, Joustra SD, Zwaveling-Soonawala N, Oostdijk W, van den Akker EL, Alders M, Santen GW, van Rijn RR, Dreschler WA, Surovtseva OV, Biermasz NR, ... ... Fliers E, et al. Mutations in TBL1X are associated with central hypothyroidism. The Journal of Clinical Endocrinology and Metabolism. jc20162531. PMID 27603907 DOI: 10.1210/jc.2016-2531  0.6
2016 Opperhuizen AL, Wang D, Foppen E, Jansen R, Boudzovitch-Surovtseva O, de Vries J, Fliers E, Kalsbeek A. Feeding during the resting phase causes profound changes in physiology and desynchronization between liver and muscle rhythms of rats. The European Journal of Neuroscience. PMID 27562056 DOI: 10.1111/ejn.13377  1
2016 Zhang Z, Foppen E, Su Y, Bisschop PH, Kalsbeek A, Fliers E, Boelen A. Metabolic effects of chronic T3 administration in the hypothalamic paraventricular and ventromedial nucleus in male rats. Endocrinology. en20161397. PMID 27533888 DOI: 10.1210/en.2016-1397  1
2016 Elbers LP, Boon HA, Moes MI, van Zaane B, Brandjes DP, Fliers E, Büller HR, Cannegieter S, Gerdes VE. Plasma Levels of Free Thyroxine and Risk of Major Bleeding in Bariatric Surgery. European Thyroid Journal. 5: 139-44. PMID 27493889 DOI: 10.1159/000446431  0.32
2016 van Rooijen G, Denys D, Fliers E, Nieuwdorp M. Effective Electroconvulsive Therapy in a Patient With Psychotic Depression With Active Cushing Disease. The Journal of Ect. PMID 27379791 DOI: 10.1097/YCT.0000000000000339  0.56
2016 van der Spek AH, Bloise FF, Tichgelaar W, Dentice M, Salvatore D, van der Wel NN, Fliers E, Boelen A. The Thyroid Hormone Inactivating Enzyme Type 3 Deiodinase is Present in Bactericidal Granules and the Cytoplasm of Human Neutrophils. Endocrinology. en20161103. PMID 27355490 DOI: 10.1210/en.2016-1103  0.6
2016 Su Y, Foppen E, Fliers E, Kalsbeek A. Effects of intracerebroventricular administration of neuropeptide Y on metabolic gene expression and energy metabolism in male rats. Endocrinology. en20161083. PMID 27267712 DOI: 10.1210/en.2016-1083  1
2016 van der Zwaal EM, de Weijer BA, van de Giessen EM, Janssen I, Berends FJ, van de Laar A, Ackermans MT, Fliers E, la Fleur SE, Booij J, Serlie MJ. Striatal dopamine D2/3 receptor availability increases after long-term bariatric surgery-induced weight loss. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27184782 DOI: 10.1016/j.euroneuro.2016.04.009  0.88
2016 Elbers LP, Moran C, Gerdes VE, van Zaane B, Meijers J, Endert E, Lyons G, Chatterjee VK, Bisschop PH, Fliers E. The Hypercoagulable state in Hyperthyroidism is mediated via the Thyroid Hormone β Receptor pathway. European Journal of Endocrinology / European Federation of Endocrine Societies. PMID 26961801 DOI: 10.1530/EJE-15-1249  1
2016 Vissenberg R, Vrijkotte TG, van der Post JA, Fliers E, Goddijn M, Bisschop PH. Abnormal thyroid function parameters in the second trimester of pregnancy are associated with breech presentation at term: a nested cohort study. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 199: 169-174. PMID 26930045 DOI: 10.1016/j.ejogrb.2016.02.028  0.76
2016 Bloise FF, van der Spek AH, Surovtseva OV, Ortiga-Carvalho TM, Fliers E, Boelen A. Differential effects of sepsis and chronic inflammation on diaphragm muscle fiber type, thyroid hormone metabolism and mitochondrial function. Thyroid : Official Journal of the American Thyroid Association. PMID 26892873 DOI: 10.1089/thy.2015.0536  0.6
2016 Zhang Z, Bisschop P, Foppen E, van Beeren HC, Kalsbeek A, Boelen A, Fliers E. A model for chronic, intrahypothalamic thyroid hormone administration in the rat. The Journal of Endocrinology. PMID 26865639 DOI: 10.1530/JOE-15-0501  1
2016 van Gucht A, Meima M, Zwaveling-Soonawala N, Visser WE, Fliers E, Wennink J, Henny C, Visser TJ, Peeters R, van Trotsenburg AS. Resistance to Thyroid Hormone Alpha in an 18 Months Old Girl; Clinical, Therapeutic and Molecular Characteristics. Thyroid : Official Journal of the American Thyroid Association. PMID 26782358 DOI: 10.1089/thy.2015.0463  1
2016 Heinen CA, Jongejan A, Watson PJ, Redeker B, Boelen A, Boudzovitch-Surovtseva O, Forzano F, Hordijk R, Kelley R, Olney AH, Pierpont ME, Schaefer GB, Stewart F, van Trotsenburg AS, Fliers E, et al. A specific mutation in TBL1XR1 causes Pierpont syndrome. Journal of Medical Genetics. PMID 26769062 DOI: 10.1136/jmedgenet-2015-103233  1
2015 van den Heuvel JK, Eggels L, van Rozen AJ, Fliers E, Kalsbeek A, Adan RA, la Fleur SE. Inhibitory Effect of the Melanocortin Receptor Agonist Melanotan-II (MTII) on Feeding Depends on Dietary Fat Content and not Obesity in Rats on Free-Choice Diets. Frontiers in Behavioral Neuroscience. 9: 358. PMID 26733840 DOI: 10.3389/fnbeh.2015.00358  1
2015 Su Y, Cailotto C, Foppen E, Jansen R, Zhang Z, Buijs R, Fliers E, Kalsbeek A. The role of feeding rhythm, adrenal hormones and neuronal inputs in synchronizing daily clock gene rhythms in the liver. Molecular and Cellular Endocrinology. PMID 26704081 DOI: 10.1016/j.mce.2015.12.011  1
2015 Su Y, Foppen E, Zhang Z, Fliers E, Kalsbeek A. Effects of 6-meals-a-day feeding and 6-meals-a-day feeding combined with adrenalectomy on daily gene expression rhythms in rat epididymal white adipose tissue. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 26567532 DOI: 10.1111/gtc.12315  1
2015 Limonard EJ, Schoenmaker T, de Vries TJ, Tanck MW, Heijboer AC, Endert E, Fliers E, Everts V, Bisschop PH. Clonidine increases bone resorption in humans. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 26439240 DOI: 10.1007/s00198-015-3312-x  1
2015 Vissenberg R, Fliers E, van der Post JA, van Wely M, Bisschop PH, Goddijn M. Live-birth rate in euthyroid women with recurrent miscarriage and thyroid peroxidase antibodies. Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology. 1-4. PMID 26430806 DOI: 10.3109/09513590.2015.1092513  1
2015 Joustra SD, Andela CD, Oostdijk W, van Trotsenburg AS, Fliers E, Wit JM, Pereira AM, Middelkoop HA, Biermasz NR. Mild deficits in attentional control in patients with the IGSF1 deficiency syndrome. Clinical Endocrinology. PMID 26387489 DOI: 10.1111/cen.12947  1
2015 Joustra SD, Roelfsema F, Endert E, Ballieux BE, van Trotsenburg AS, Fliers E, Corssmit EP, Bernard DJ, Oostdijk W, Wit JM, Pereira AM, Biermasz NR. Pituitary Hormone Secretion Profiles in IGSF1 Deficiency Syndrome. Neuroendocrinology. PMID 26336917 DOI: 10.1159/000439433  1
2015 Vissenberg R, van Dijk MM, Fliers E, van der Post JA, van Wely M, Bloemenkamp KW, Hoek A, Kuchenbecker WK, H R Verhoeve, H C J Scheepers, Rombout-de Weerd S, Koks C, Zwart JJ, Broekmans F, Verpoest W, et al. Effect of levothyroxine on live birth rate in euthyroid women with recurrent miscarriage and TPO antibodies (T4-LIFE study). Contemporary Clinical Trials. PMID 26255238 DOI: 10.1016/j.cct.2015.08.005  1
2015 Bruinstroop E, Eliveld J, Foppen E, Busker S, Ackermans MT, Fliers E, Kalsbeek A. Hepatic denervation and dyslipidemia in obese Zucker (fa/fa) rats. International Journal of Obesity (2005). PMID 26134416 DOI: 10.1038/ijo.2015.122  1
2015 Fliers E, Bianco AC, Langouche L, Boelen A. Thyroid function in critically ill patients. The Lancet. Diabetes & Endocrinology. 3: 816-25. PMID 26071885 DOI: 10.1016/S2213-8587(15)00225-9  1
2015 Limonard EJ, Veldhuis-Vlug AG, van Dussen L, Runge JH, Tanck MW, Endert E, Heijboer AC, Fliers E, Hollak CE, Akkerman EM, Bisschop PH. Short-Term Effect of Estrogen on Human Bone Marrow Fat. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 2058-66. PMID 25982922 DOI: 10.1002/jbmr.2557  1
2015 de Vries EM, Fliers E, Boelen A. The molecular basis of the non-thyroidal illness syndrome. The Journal of Endocrinology. 225: R67-81. PMID 25972358 DOI: 10.1530/JOE-15-0133  1
2015 Veldhuis-Vlug AG, Oei L, Souverein PC, Tanck MW, Rivadeneira F, Zillikens MC, Kamphuisen PW, Maitland-van der Zee AH, de Groot MC, Hofman A, Uitterlinden AG, Fliers E, de Boer A, Bisschop PH. Association of polymorphisms in the beta-2 adrenergic receptor gene with fracture risk and bone mineral density. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 26: 2019-27. PMID 25910744 DOI: 10.1007/s00198-015-3087-0  1
2015 de Fost M, Oussaada SM, Endert E, Linthorst GE, Serlie MJ, Soeters MR, DeVries JH, Bisschop PH, Fliers E. The water deprivation test and a potential role for the arginine vasopressin precursor copeptin to differentiate diabetes insipidus from primary polydipsia. Endocrine Connections. 4: 86-91. PMID 25712898 DOI: 10.1530/EC-14-0113  0.84
2015 Vissenberg R, Manders VD, Mastenbroek S, Fliers E, Afink GB, Ris-Stalpers C, Goddijn M, Bisschop PH. Pathophysiological aspects of thyroid hormone disorders/thyroid peroxidase autoantibodies and reproduction. Human Reproduction Update. 21: 378-87. PMID 25634660 DOI: 10.1093/humupd/dmv004  1
2015 Bisschop PH, Fliers E, Kalsbeek A. Autonomic regulation of hepatic glucose production. Comprehensive Physiology. 5: 147-65. PMID 25589267 DOI: 10.1002/cphy.c140009  1
2015 van Santen HM, Schouten-Meeteren AY, Serlie M, Meijneke RW, van Trotsenburg AS, Verberne H, Holleman F, Fliers E. Effects of T3 treatment on brown adipose tissue and energy expenditure in a patient with craniopharyngioma and hypothalamic obesity. Journal of Pediatric Endocrinology & Metabolism : Jpem. 28: 53-7. PMID 25514327 DOI: 10.1515/jpem-2014-0337  1
2015 Veldhuis-Vlug AG, Tanck MW, Limonard EJ, Endert E, Heijboer AC, Lips P, Fliers E, Bisschop PH. The effects of beta-2 adrenergic agonist and antagonist on human bone metabolism: a randomized controlled trial. Bone. 71: 196-200. PMID 25451321 DOI: 10.1016/j.bone.2014.10.024  1
2015 Limonard EJ, van Schoor NM, de Jongh RT, Lips P, Fliers E, Bisschop PH. Osteocalcin and the pituitary-gonadal axis in older men: a population-based study. Clinical Endocrinology. 82: 753-9. PMID 25376262 DOI: 10.1111/cen.12660  1
2015 de Vries EM, van Beeren HC, Ackermans MT, Kalsbeek A, Fliers E, Boelen A. Differential effects of fasting vs food restriction on liver thyroid hormone metabolism in male rats. The Journal of Endocrinology. 224: 25-35. PMID 25349245 DOI: 10.1530/JOE-14-0533  1
2015 Oosterman JE, Foppen E, van der Spek R, Fliers E, Kalsbeek A, la Fleur SE. Timing of fat and liquid sugar intake alters substrate oxidation and food efficiency in male Wistar rats. Chronobiology International. 32: 289-98. PMID 25317718 DOI: 10.3109/07420528.2014.971177  1
2015 Su Y, van der Spek R, Foppen E, Kwakkel J, Fliers E, Kalsbeek A. Effects of adrenalectomy on daily gene expression rhythms in the rat suprachiasmatic and paraventricular hypothalamic nuclei and in white adipose tissue. Chronobiology International. 32: 211-24. PMID 25268283 DOI: 10.3109/07420528.2014.963198  1
2015 van den Heuvel JK, Furman K, Gumbs MC, Eggels L, Opland DM, Land BB, Kolk SM, S Narayanan N, Fliers E, Kalsbeek A, DiLeone RJ, la Fleur SE. Neuropeptide Y activity in the nucleus accumbens modulates feeding behavior and neuronal activity. Biological Psychiatry. 77: 633-41. PMID 25109664 DOI: 10.1016/j.biopsych.2014.06.008  1
2014 La Fleur SE, Fliers E, Kalsbeek A. Neuroscience of glucose homeostasis. Handbook of Clinical Neurology. 126: 341-51. PMID 25410233 DOI: 10.1016/B978-0-444-53480-4.00026-6  1
2014 Bruinstroop E, Fliers E, Kalsbeek A. Hypothalamic control of hepatic lipid metabolism via the autonomic nervous system. Best Practice & Research. Clinical Endocrinology & Metabolism. 28: 673-84. PMID 25256763 DOI: 10.1016/j.beem.2014.05.001  1
2014 Fliers E, Kalsbeek A. Preface. Best Practice & Research. Clinical Endocrinology & Metabolism. 28: 633-4. PMID 25256759 DOI: 10.1016/j.beem.2014.04.006  1
2014 Fliers E, Korbonits M, Romijn JA. Preface. Handbook of Clinical Neurology. 124: ix. PMID 25248605 DOI: 10.1016/B978-0-444-59602-4.09984-6  1
2014 Fliers E, Boelen A, van Trotsenburg AS. Central regulation of the hypothalamo-pituitary-thyroid (HPT) axis: focus on clinical aspects. Handbook of Clinical Neurology. 124: 127-38. PMID 25248584 DOI: 10.1016/B978-0-444-59602-4.00009-5  1
2014 de Vries EM, Eggels L, van Beeren HC, Ackermans MT, Kalsbeek A, Fliers E, Boelen A. Fasting-induced changes in hepatic thyroid hormone metabolism in male rats are independent of autonomic nervous input to the liver. Endocrinology. 155: 5033-41. PMID 25243858 DOI: 10.1210/en.2014-1608  1
2014 van Zeijl CJ, Surovtseva OV, Kwakkel J, van Beeren HC, Bassett JH, Duncan Bassett JH, Williams GR, Wiersinga WM, Fliers E, Boelen A. Thyrostimulin deficiency does not alter peripheral responses to acute inflammation-induced nonthyroidal illness. American Journal of Physiology. Endocrinology and Metabolism. 307: E527-37. PMID 25117405 DOI: 10.1152/ajpendo.00266.2014  1
2014 Stenvers DJ, Schouten LJ, Jurgens J, Endert E, Kalsbeek A, Fliers E, Bisschop PH. Breakfast replacement with a low-glycaemic response liquid formula in patients with type 2 diabetes: a randomised clinical trial. The British Journal of Nutrition. 112: 504-12. PMID 25091284 DOI: 10.1017/S0007114514001123  1
2014 Fliers E, Kalsbeek A, Boelen A. Beyond the fixed setpoint of the hypothalamus-pituitary-thyroid axis. European Journal of Endocrinology / European Federation of Endocrine Societies. 171: R197-208. PMID 25005935 DOI: 10.1530/EJE-14-0285  1
2014 Kalsbeek A, la Fleur S, Fliers E. Circadian control of glucose metabolism. Molecular Metabolism. 3: 372-83. PMID 24944897 DOI: 10.1016/j.molmet.2014.03.002  1
2014 Borgers AJ, Koopman KE, Bisschop PH, Serlie MJ, Swaab DF, Fliers E, la Fleur SE, Alkemade A. Decreased serotonin transporter immunoreactivity in the human hypothalamic infundibular nucleus of overweight subjects. Frontiers in Neuroscience. 8: 106. PMID 24860418 DOI: 10.3389/fnins.2014.00106  1
2014 Lammers NM, Sondermeijer BM, Twickler TB, de Bie RM, Ackermans MT, Fliers E, Schuurman PR, La Fleur SE, Serlie MJ. Subthalamic nucleus stimulation does not influence basal glucose metabolism or insulin sensitivity in patients with Parkinson's disease. Frontiers in Neuroscience. 8: 95. PMID 24860415 DOI: 10.3389/fnins.2014.00095  1
2014 Martínez de Morentin PB, González-García I, Martins L, Lage R, Fernández-Mallo D, Martínez-Sánchez N, Ruíz-Pino F, Liu J, Morgan DA, Pinilla L, Gallego R, Saha AK, Kalsbeek A, Fliers E, Bisschop PH, et al. Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK. Cell Metabolism. 20: 41-53. PMID 24856932 DOI: 10.1016/j.cmet.2014.03.031  1
2014 Elbers LP, van Zaane B, Gerdes VE, Coutinho JM, Bisschop PH, Fliers E. Venous thromboembolism in overt hyperthyroidism - a direct association with clinical implications? The Netherlands Journal of Medicine. 72: 242-4. PMID 24829185  1
2014 Kalsbeek A, Bruinstroop E, Yi CX, Klieverik L, Liu J, Fliers E. Hormonal control of metabolism by the hypothalamus-autonomic nervous system-liver axis. Frontiers of Hormone Research. 42: 1-28. PMID 24732922 DOI: 10.1159/000358312  1
2014 Kwakkel J, Surovtseva OV, de Vries EM, Stap J, Fliers E, Boelen A. A novel role for the thyroid hormone-activating enzyme type 2 deiodinase in the inflammatory response of macrophages. Endocrinology. 155: 2725-34. PMID 24731098 DOI: 10.1210/en.2013-2066  1
2014 van den Heuvel JK, Eggels L, van Rozen AJ, Luijendijk MC, Fliers E, Kalsbeek A, Adan RA, la Fleur SE. Neuropeptide Y and leptin sensitivity is dependent on diet composition. Journal of Neuroendocrinology. 26: 377-85. PMID 24698502 DOI: 10.1111/jne.12155  1
2014 Koopman KE, Caan MW, Nederveen AJ, Pels A, Ackermans MT, Fliers E, la Fleur SE, Serlie MJ. Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: a randomized controlled trial. Hepatology (Baltimore, Md.). 60: 545-53. PMID 24668862 DOI: 10.1002/hep.27149  1
2014 de Vries EM, Kwakkel J, Eggels L, Kalsbeek A, Barrett P, Fliers E, Boelen A. NFκB signaling is essential for the lipopolysaccharide-induced increase of type 2 deiodinase in tanycytes. Endocrinology. 155: 2000-8. PMID 24635351 DOI: 10.1210/en.2013-2018  1
2014 de Weijer BA, van de Giessen E, Janssen I, Berends FJ, van de Laar A, Ackermans MT, Fliers E, la Fleur SE, Booij J, Serlie MJ. Striatal dopamine receptor binding in morbidly obese women before and after gastric bypass surgery and its relationship with insulin sensitivity. Diabetologia. 57: 1078-80. PMID 24500343 DOI: 10.1007/s00125-014-3178-z  1
2014 van den Heuvel JK, Eggels L, Fliers E, Kalsbeek A, Adan RA, la Fleur SE. Differential modulation of arcuate nucleus and mesolimbic gene expression levels by central leptin in rats on short-term high-fat high-sugar diet. Plos One. 9: e87729. PMID 24498181 DOI: 10.1371/journal.pone.0087729  1
2014 Roelfsema F, Pijl H, Kok P, Endert E, Fliers E, Biermasz NR, Pereira AM, Veldhuis JD. Thyrotropin secretion in healthy subjects is robust and independent of age and gender, and only weakly dependent on body mass index. The Journal of Clinical Endocrinology and Metabolism. 99: 570-8. PMID 24276453 DOI: 10.1210/jc.2013-2858  1
2014 Girault EM, Guigas B, Alkemade A, Foppen E, Ackermans MT, la Fleur SE, Fliers E, Kalsbeek A. Chronic treatment with olanzapine increases adiposity by changing fuel substrate and causes desensitization of the acute metabolic side effects. Naunyn-Schmiedeberg's Archives of Pharmacology. 387: 185-95. PMID 24190543 DOI: 10.1007/s00210-013-0933-5  1
2014 van Varsseveld NC, Bisschop PH, Biermasz NR, Pereira AM, Fliers E, Drent ML. A long-term follow-up study of eighteen patients with thyrotrophin-secreting pituitary adenomas. Clinical Endocrinology. 80: 395-402. PMID 23848527 DOI: 10.1111/cen.12290  1
2014 Eskes SA, Endert E, Fliers E, Birnie E, Hollenbach B, Schomburg L, Köhrle J, Wiersinga WM. Selenite supplementation in euthyroid subjects with thyroid peroxidase antibodies. Clinical Endocrinology. 80: 444-51. PMID 23844613 DOI: 10.1111/cen.12284  1
2013 Diepenbroek C, van der Plasse G, Eggels L, Rijnsburger M, Feenstra MG, Kalsbeek A, Denys D, Fliers E, Serlie MJ, la Fleur SE. Alterations in blood glucose and plasma glucagon concentrations during deep brain stimulation in the shell region of the nucleus accumbens in rats. Frontiers in Neuroscience. 7: 226. PMID 24339800 DOI: 10.3389/fnins.2013.00226  1
2013 Koopman KE, Booij J, Fliers E, Serlie MJ, la Fleur SE. Diet-induced changes in the Lean Brain: Hypercaloric high-fat-high-sugar snacking decreases serotonin transporters in the human hypothalamic region. Molecular Metabolism. 2: 417-22. PMID 24327957 DOI: 10.1016/j.molmet.2013.07.006  1
2013 Veldhuis-Vlug AG, Fliers E, Bisschop PH. Bone as a regulator of glucose metabolism. The Netherlands Journal of Medicine. 71: 396-400. PMID 24127499  1
2013 de Weijer BA, Aarts E, Janssen IM, Berends FJ, van de Laar A, Kaasjager K, Ackermans MT, Fliers E, Serlie MJ. Hepatic and peripheral insulin sensitivity do not improve 2 weeks after bariatric surgery. Obesity (Silver Spring, Md.). 21: 1143-7. PMID 23913729 DOI: 10.1002/oby.20220  1
2013 Diepenbroek C, Serlie MJ, Fliers E, Kalsbeek A, la Fleur SE. Brain areas and pathways in the regulation of glucose metabolism. Biofactors (Oxford, England). 39: 505-13. PMID 23913677 DOI: 10.1002/biof.1123  1
2013 Girault EM, Toonen PW, Eggels L, Foppen E, Ackermans MT, la Fleur SE, Fliers E, Kalsbeek A. Olanzapine-induced changes in glucose metabolism are independent of the melanin-concentrating hormone system. Psychoneuroendocrinology. 38: 2640-6. PMID 23856185 DOI: 10.1016/j.psyneuen.2013.06.021  1
2013 Girault EM, Foppen E, Ackermans MT, Fliers E, Kalsbeek A. Central administration of an orexin receptor 1 antagonist prevents the stimulatory effect of Olanzapine on endogenous glucose production. Brain Research. 1527: 238-45. PMID 23830851 DOI: 10.1016/j.brainres.2013.06.034  1
2013 Borgers AJ, Alkemade A, Van de Giessen EM, Drent ML, Booij J, Bisschop PH, Fliers E. Imaging of serotonin transporters with [123I]FP-CIT SPECT in the human hypothalamus. Ejnmmi Research. 3: 34. PMID 23618227 DOI: 10.1186/2191-219X-3-34  1
2013 Kalsbeek A, Fliers E. Daily regulation of hormone profiles. Handbook of Experimental Pharmacology. 185-226. PMID 23604480 DOI: 10.1007/978-3-642-25950-0_8  1
2013 Grandiek M, van Campen JP, Fliers E. An unusual cause of hyponatremia in an older adult. Journal of the American Geriatrics Society. 61: 658-9. PMID 23581927 DOI: 10.1111/jgs.12180  1
2013 Bruinstroop E, la Fleur SE, Ackermans MT, Foppen E, Wortel J, Kooijman S, Berbée JF, Rensen PC, Fliers E, Kalsbeek A. The autonomic nervous system regulates postprandial hepatic lipid metabolism. American Journal of Physiology. Endocrinology and Metabolism. 304: E1089-96. PMID 23531617 DOI: 10.1152/ajpendo.00614.2012  1
2013 Meijer JA, Bakker LE, Valk GD, de Herder WW, de Wilt JH, Netea-Maier RT, Schaper N, Fliers E, Lips P, Plukker JT, Links TP, Smit JA. Radioactive iodine in the treatment of medullary thyroid carcinoma: a controlled multicenter study. European Journal of Endocrinology / European Federation of Endocrine Societies. 168: 779-86. PMID 23462866 DOI: 10.1530/EJE-12-0943  1
2013 de Koning PP, Figee M, Endert E, Storosum JG, Fliers E, Denys D. Deep brain stimulation for obsessive-compulsive disorder is associated with cortisol changes. Psychoneuroendocrinology. 38: 1455-9. PMID 23333254 DOI: 10.1016/j.psyneuen.2012.12.006  1
2013 Varewijck AJ, Boelen A, Lamberts SW, Fliers E, Hofland LJ, Wiersinga WM, Janssen JA. Circulating IgGs may modulate IGF-I receptor stimulating activity in a subset of patients with Graves' ophthalmopathy. The Journal of Clinical Endocrinology and Metabolism. 98: 769-76. PMID 23295466 DOI: 10.1210/jc.2012-2270  1
2013 Bisschop PH, Dekker MJ, Osterthun W, Kwakkel J, Anink JJ, Boelen A, Unmehopa UA, Koper JW, Lamberts SW, Stewart PM, Swaab DF, Fliers E. Expression of 11β-hydroxysteroid dehydrogenase type 1 in the human hypothalamus. Journal of Neuroendocrinology. 25: 425-32. PMID 23286317 DOI: 10.1111/jne.12017  1
2013 Borgers AJ, Fliers E, Siljee JE, Swaab DF, Van Someren EJ, Bisschop PH, Alkemade A. Arginine vasopressin immunoreactivity is decreased in the hypothalamic suprachiasmatic nucleus of subjects with suprasellar tumors. Brain Pathology (Zurich, Switzerland). 23: 440-4. PMID 23278971 DOI: 10.1111/bpa.12016  1
2013 Siljee JE, Unmehopa UA, Kalsbeek A, Swaab DF, Fliers E, Alkemade A. Melanocortin 4 receptor distribution in the human hypothalamus. European Journal of Endocrinology / European Federation of Endocrine Societies. 168: 361-9. PMID 23211571 DOI: 10.1530/EJE-12-0750  1
2013 Liu J, Bisschop PH, Eggels L, Foppen E, Ackermans MT, Zhou JN, Fliers E, Kalsbeek A. Intrahypothalamic estradiol regulates glucose metabolism via the sympathetic nervous system in female rats. Diabetes. 62: 435-43. PMID 23139356 DOI: 10.2337/db12-0488  1
2013 van Bunderen CC, van Varsseveld NC, Baayen JC, van Furth WR, Aliaga ES, Hazewinkel MJ, Majoie CB, Freling NJ, Lips P, Fliers E, Bisschop PH, Drent ML. Predictors of endoscopic transsphenoidal surgery outcome in acromegaly: patient and tumor characteristics evaluated by magnetic resonance imaging. Pituitary. 16: 158-67. PMID 22535510 DOI: 10.1007/s11102-012-0395-7  1
2013 Kalsbeek A, Fliers E. Hypothalamus Neuroscience in the 21st Century: From Basic to Clinical. 1365-1405. DOI: 10.1007/978-1-4614-1997-6_47  1
2013 Vissenberg R, Goddijn M, Mol BW, Van Der Post JA, Fliers E, Bisschop PH. Thyroid disease in pregnant women: Clinical dilemmas | Schildklierdisfunctie bij zwangeren: Klinische dilemma's Nederlands Tijdschrift Voor Geneeskunde. 157.  1
2012 Boelen A, Kwakkel J, Fliers E. Thyroid hormone receptors in health and disease. Minerva Endocrinologica. 37: 291-304. PMID 23235186  1
2012 Vissenberg R, Goddijn M, Mol BW, van der Post JA, Fliers E, Bisschop PH. [Thyroid dysfunction in pregnant women: clinical dilemmas]. Nederlands Tijdschrift Voor Geneeskunde. 156: A5163. PMID 23218031  1
2012 Veldhuis-Vlug AG, El Mahdiui M, Endert E, Heijboer AC, Fliers E, Bisschop PH. Bone resorption is increased in pheochromocytoma patients and normalizes following adrenalectomy. The Journal of Clinical Endocrinology and Metabolism. 97: E2093-7. PMID 22990094 DOI: 10.1210/jc.2012-2823  1
2012 Louwerens M, Appelhof BC, Verloop H, Medici M, Peeters RP, Visser TJ, Boelen A, Fliers E, Smit JW, Dekkers OM. Fatigue and fatigue-related symptoms in patients treated for different causes of hypothyroidism. European Journal of Endocrinology / European Federation of Endocrine Societies. 167: 809-15. PMID 22989469 DOI: 10.1530/EJE-12-0501  1
2012 van Beeren HC, Kwakkel J, Ackermans MT, Wiersinga WM, Fliers E, Boelen A. Action of specific thyroid hormone receptor α(1) and β(1) antagonists in the central and peripheral regulation of thyroid hormone metabolism in the rat. Thyroid : Official Journal of the American Thyroid Association. 22: 1275-82. PMID 22985455 DOI: 10.1089/thy.2012.0135  1
2012 Romeijn N, Borgers AJ, Fliers E, Alkemade A, Bisschop PH, Van Someren EJ. Medical history of optic chiasm compression in patients with pituitary insufficiency affects skin temperature and its relation to sleep. Chronobiology International. 29: 1098-108. PMID 22924389 DOI: 10.3109/07420528.2012.708000  1
2012 Girault EM, Alkemade A, Foppen E, Ackermans MT, Fliers E, Kalsbeek A. Acute peripheral but not central administration of olanzapine induces hyperglycemia associated with hepatic and extra-hepatic insulin resistance. Plos One. 7: e43244. PMID 22905238 DOI: 10.1371/journal.pone.0043244  1
2012 Stenvers DJ, Jonkers CF, Fliers E, Bisschop PH, Kalsbeek A. Nutrition and the circadian timing system. Progress in Brain Research. 199: 359-76. PMID 22877675 DOI: 10.1016/B978-0-444-59427-3.00020-4  1
2012 van der Spek R, Kreier F, Fliers E, Kalsbeek A. Circadian rhythms in white adipose tissue. Progress in Brain Research. 199: 183-201. PMID 22877666 DOI: 10.1016/B978-0-444-59427-3.00011-3  1
2012 Wentholt IM, Bras J, Kroon FH, Nieveen van Dijkum EJ, Fliers E. Vitamin D, or wait and see? The Netherlands Journal of Medicine. 70: 292-3. PMID 22859425  1
2012 Kalsbeek A, Liu J, Lei J, Timmermans L, Foppen E, Cailotto C, Fliers E. Differential involvement of the suprachiasmatic nucleus in lipopolysaccharide-induced plasma glucose and corticosterone responses. Chronobiology International. 29: 835-49. PMID 22823867 DOI: 10.3109/07420528.2012.699123  1
2012 Girault EM, Yi CX, Fliers E, Kalsbeek A. Orexins, feeding, and energy balance. Progress in Brain Research. 198: 47-64. PMID 22813969 DOI: 10.1016/B978-0-444-59489-1.00005-7  1
2012 Friesema EC, Visser TJ, Borgers AJ, Kalsbeek A, Swaab DF, Fliers E, Alkemade A. Thyroid hormone transporters and deiodinases in the developing human hypothalamus. European Journal of Endocrinology / European Federation of Endocrine Societies. 167: 379-86. PMID 22723621 DOI: 10.1530/EJE-12-0177  1
2012 Koopman KE, la Fleur SE, Fliers E, Serlie MJ, Booij J. Assessing the optimal time point for the measurement of extrastriatal serotonin transporter binding with 123I-FP-CIT SPECT in healthy, male subjects. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1087-90. PMID 22627000 DOI: 10.2967/jnumed.111.102277  1
2012 Liu J, Bisschop PH, Eggels L, Foppen E, Fliers E, Zhou JN, Kalsbeek A. Intrahypothalamic estradiol modulates hypothalamus-pituitary-adrenal-axis activity in female rats. Endocrinology. 153: 3337-44. PMID 22562172 DOI: 10.1210/en.2011-2176  1
2012 Alkemade A, Yi CX, Pei L, Harakalova M, Swaab DF, la Fleur SE, Fliers E, Kalsbeek A. AgRP and NPY expression in the human hypothalamic infundibular nucleus correlate with body mass index, whereas changes in αMSH are related to type 2 diabetes. The Journal of Clinical Endocrinology and Metabolism. 97: E925-33. PMID 22492775 DOI: 10.1210/jc.2011-3259  1
2012 Fliers E, van Furth WR, Bisschop PH. Cure of a thyrotrophin (TSH)-secreting pituitary adenoma by medical therapy. Clinical Endocrinology. 77: 788-90. PMID 22486560 DOI: 10.1111/j.1365-2265.2012.04405.x  1
2012 Bruinstroop E, Pei L, Ackermans MT, Foppen E, Borgers AJ, Kwakkel J, Alkemade A, Fliers E, Kalsbeek A. Hypothalamic neuropeptide Y (NPY) controls hepatic VLDL-triglyceride secretion in rats via the sympathetic nervous system. Diabetes. 61: 1043-50. PMID 22461566 DOI: 10.2337/db11-1142  1
2012 Limonard EJ, Bisschop PH, Fliers E, Nieveen van Dijkum EJ. Thyroid function after subtotal thyroidectomy in patients with Graves' hyperthyroidism. Thescientificworldjournal. 2012: 548796. PMID 22448136 DOI: 10.1100/2012/548796  1
2012 Vissenberg R, van den Boogaard E, van Wely M, van der Post JA, Fliers E, Bisschop PH, Goddijn M. Treatment of thyroid disorders before conception and in early pregnancy: a systematic review. Human Reproduction Update. 18: 360-73. PMID 22431565 DOI: 10.1093/humupd/dms007  1
2012 Alkemade A, Unmehopa UA, Hessel EV, Swaab DF, Kalsbeek A, Fliers E. Suppressor of cytokine signaling 3 in the human hypothalamus. Peptides. 35: 139-42. PMID 22425648 DOI: 10.1016/j.peptides.2012.03.004  1
2012 van Zeijl CJ, van Koppen CJ, Surovtseva OV, de Gooyer ME, Plate R, Conti P, Karstens WJ, Timmers M, Saeed P, Wiersinga WM, Miltenburg AM, Fliers E, Boelen A. Complete inhibition of rhTSH-, Graves' disease IgG-, and M22-induced cAMP production in differentiated orbital fibroblasts by a low-molecular-weight TSHR antagonist. The Journal of Clinical Endocrinology and Metabolism. 97: E781-5. PMID 22419705 DOI: 10.1210/jc.2011-2931  1
2012 Sondermeijer BM, Klein Twennaar CF, Kastelein JJ, Franssen EJ, Hutten BA, Dallinga-Thie GM, Stroes ES, Fliers E, Twickler MT, Serlie MJ. Infusion of a lipid emulsion in healthy men decreases the serotonergic response. Neuroendocrinology. 95: 325-31. PMID 22327404 DOI: 10.1159/000333038  1
2012 Borgers AJ, Alkemade A, Venema HW, Fliers E, Bisschop PH. A history of cranial radiotherapy is associated with a higher visceral to subcutaneous fat ratio in men with pituitary insufficiency. European Journal of Endocrinology / European Federation of Endocrine Societies. 166: 619-24. PMID 22247015 DOI: 10.1530/EJE-11-1023  1
2012 Kootte RS, Stuijver DJ, Dekkers OM, van Zaane B, Fliers E, Cannegieter SC, Gerdes VE. The incidence of venous thromboembolism in patients with overt hyperthyroidism: a retrospective multicentre cohort study. Thrombosis and Haemostasis. 107: 417-22. PMID 22234657 DOI: 10.1160/TH11-10-0691  1
2012 Yi CX, Foppen E, Abplanalp W, Gao Y, Alkemade A, la Fleur SE, Serlie MJ, Fliers E, Buijs RM, Tschöp MH, Kalsbeek A. Glucocorticoid signaling in the arcuate nucleus modulates hepatic insulin sensitivity. Diabetes. 61: 339-45. PMID 22210324 DOI: 10.2337/db11-1239  1
2012 Boelen A, van Beeren M, Vos X, Surovtseva O, Belegri E, Saaltink DJ, Vreugdenhil E, Kalsbeek A, Kwakkel J, Fliers E. Leptin administration restores the fasting-induced increase of hepatic type 3 deiodinase expression in mice. Thyroid : Official Journal of the American Thyroid Association. 22: 192-9. PMID 22175243 DOI: 10.1089/thy.2011.0289  1
2012 Eskes SA, Endert E, Fliers E, Geskus RB, Dullaart RP, Links TP, Wiersinga WM. Treatment of amiodarone-induced thyrotoxicosis type 2: a randomized clinical trial. The Journal of Clinical Endocrinology and Metabolism. 97: 499-506. PMID 22130792 DOI: 10.1210/jc.2011-2390  1
2012 Kalsbeek A, van der Spek R, Lei J, Endert E, Buijs RM, Fliers E. Circadian rhythms in the hypothalamo-pituitary-adrenal (HPA) axis. Molecular and Cellular Endocrinology. 349: 20-9. PMID 21782883 DOI: 10.1016/j.mce.2011.06.042  1
2011 de Weijer BA, van de Giessen E, van Amelsvoort TA, Boot E, Braak B, Janssen IM, van de Laar A, Fliers E, Serlie MJ, Booij J. Lower striatal dopamine D2/3 receptor availability in obese compared with non-obese subjects. Ejnmmi Research. 1: 37. PMID 22214469 DOI: 10.1186/2191-219X-1-37  1
2011 Klieverik LP, Kalsbeek A, Ackermans MT, Sauerwein HP, Wiersinga WM, Fliers E. Energy Homeostasis and Body Weight before and after Cessation of Block and Replacement Therapy in Euthyroid Patients with Graves' Disease. International Journal of Endocrinology. 2011: 715370. PMID 22190927 DOI: 10.1155/2011/715370  1
2011 Stuijver DJ, van Zaane B, Feelders RA, Debeij J, Cannegieter SC, Hermus AR, van den Berg G, Pereira AM, de Herder WW, Wagenmakers MA, Kerstens MN, Zelissen PM, Fliers E, Schaper N, Drent ML, et al. Incidence of venous thromboembolism in patients with Cushing's syndrome: a multicenter cohort study. The Journal of Clinical Endocrinology and Metabolism. 96: 3525-32. PMID 21880802 DOI: 10.1210/jc.2011-1661  1
2011 Kalsbeek A, Yi CX, Cailotto C, la Fleur SE, Fliers E, Buijs RM. Mammalian clock output mechanisms. Essays in Biochemistry. 49: 137-51. PMID 21819389 DOI: 10.1042/bse0490137  1
2011 Boelen A, Kwakkel J, Fliers E. Beyond low plasma T3: local thyroid hormone metabolism during inflammation and infection. Endocrine Reviews. 32: 670-93. PMID 21791567 DOI: 10.1210/er.2011-0007  1
2011 Kwakkel J, Fliers E, Boelen A. Illness-induced changes in thyroid hormone metabolism: focus on the tissue level. The Netherlands Journal of Medicine. 69: 224-8. PMID 21646671  1
2011 Serlie MJ, La Fleur SE, Fliers E. Obesity: is evolution to blame? The Netherlands Journal of Medicine. 69: 156-8. PMID 21527801  1
2011 Borgers AJ, Romeijn N, van Someren E, Fliers E, Alkemade A, Bisschop PH. Compression of the optic chiasm is associated with permanent shorter sleep duration in patients with pituitary insufficiency. Clinical Endocrinology. 75: 347-53. PMID 21521321 DOI: 10.1111/j.1365-2265.2011.04053.x  1
2011 Alkemade A, Friesema EC, Kalsbeek A, Swaab DF, Visser TJ, Fliers E. Expression of thyroid hormone transporters in the human hypothalamus. The Journal of Clinical Endocrinology and Metabolism. 96: E967-71. PMID 21508134 DOI: 10.1210/jc.2010-2750  1
2011 de Fost M, van Trotsenburg AS, van Santen HM, Endert E, van den Elzen C, Kamsteeg EJ, Swaab DF, Fliers E. Familial neurohypophyseal diabetes insipidus due to a novel mutation in the arginine vasopressin-neurophysin II gene. European Journal of Endocrinology / European Federation of Endocrine Societies. 165: 161-5. PMID 21498630 DOI: 10.1530/EJE-11-0048  1
2011 Kalsbeek A, Scheer FA, Perreau-Lenz S, La Fleur SE, Yi CX, Fliers E, Buijs RM. Circadian disruption and SCN control of energy metabolism. Febs Letters. 585: 1412-26. PMID 21414317 DOI: 10.1016/j.febslet.2011.03.021  1
2011 van Zeijl CJ, Surovtseva OV, Wiersinga WM, Fliers E, Boelen A. Acute inflammation increases pituitary and hypothalamic glycoprotein hormone subunit B5 mRNA expression in association with decreased thyrotrophin receptor mRNA expression in mice. Journal of Neuroendocrinology. 23: 310-9. PMID 21314737 DOI: 10.1111/j.1365-2826.2011.02116.x  1
2011 van Zeijl CJ, Fliers E, van Koppen CJ, Surovtseva OV, de Gooyer ME, Mourits MP, Wiersinga WM, Miltenburg AM, Boelen A. Thyrotropin receptor-stimulating Graves' disease immunoglobulins induce hyaluronan synthesis by differentiated orbital fibroblasts from patients with Graves' ophthalmopathy not only via cyclic adenosine monophosphate signaling pathways. Thyroid : Official Journal of the American Thyroid Association. 21: 169-76. PMID 20954819 DOI: 10.1089/thy.2010.0123  1
2010 Kalsbeek A, Bruinstroop E, Yi CX, Klieverik LP, La Fleur SE, Fliers E. Hypothalamic control of energy metabolism via the autonomic nervous system. Annals of the New York Academy of Sciences. 1212: 114-29. PMID 21070249 DOI: 10.1111/j.1749-6632.2010.05800.x  1
2010 Kalsbeek A, Yi CX, la Fleur SE, Buijs RM, Fliers E. Suprachiasmatic nucleus and autonomic nervous system influences on awakening from sleep. International Review of Neurobiology. 93: 91-107. PMID 20970002 DOI: 10.1016/S0074-7742(10)93004-3  1
2010 Fliers E, Boelen A. Type 2 deiodinase and brown fat: the heat is on--or off. Endocrinology. 151: 4087-9. PMID 20736402 DOI: 10.1210/en.2010-0712  1
2010 Ackermans MT, Klieverik LP, Ringeling P, Endert E, Kalsbeek A, Fliers E. An online solid-phase extraction-liquid chromatography-tandem mass spectrometry method to study the presence of thyronamines in plasma and tissue and their putative conversion from 13C6-thyroxine. The Journal of Endocrinology. 206: 327-34. PMID 20603264 DOI: 10.1677/JOE-10-0060  1
2010 van Zeijl CJ, Fliers E, van Koppen CJ, Surovtseva OV, de Gooyer ME, Mourits MP, Wiersinga WM, Miltenburg AM, Boelen A. Effects of thyrotropin and thyrotropin-receptor-stimulating Graves' disease immunoglobulin G on cyclic adenosine monophosphate and hyaluronan production in nondifferentiated orbital fibroblasts of Graves' ophthalmopathy patients. Thyroid : Official Journal of the American Thyroid Association. 20: 535-44. PMID 20384487 DOI: 10.1089/thy.2009.0447  1
2010 Yi CX, Sun N, Ackermans MT, Alkemade A, Foppen E, Shi J, Serlie MJ, Buijs RM, Fliers E, Kalsbeek A. Pituitary adenylate cyclase-activating polypeptide stimulates glucose production via the hepatic sympathetic innervation in rats. Diabetes. 59: 1591-600. PMID 20357362 DOI: 10.2337/db09-1398  1
2010 van Zaane B, Squizzato A, Huijgen R, van Zanten AP, Fliers E, Cannegieter SC, Büller HR, Gerdes VE, Brandjes DP. Increasing levels of free thyroxine as a risk factor for a first venous thrombosis: a case-control study. Blood. 115: 4344-9. PMID 20308594 DOI: 10.1182/blood-2009-11-253724  1
2010 Kalsbeek A, Yi CX, La Fleur SE, Fliers E. The hypothalamic clock and its control of glucose homeostasis. Trends in Endocrinology and Metabolism: Tem. 21: 402-10. PMID 20303779 DOI: 10.1016/j.tem.2010.02.005  1
2010 Eskes SA, Endert E, Fliers E, Wiersinga WM. Prevalence of growth hormone deficiency in Hashimoto's thyroiditis. The Journal of Clinical Endocrinology and Metabolism. 95: 2266-70. PMID 20228167 DOI: 10.1210/jc.2009-2016  1
2010 van Zeijl CJ, Surovtseva OV, Wiersinga WM, Boelen A, Fliers E. Transient hypothyroxinemia in juvenile glycoprotein hormone subunit B5 knock-out mice. Molecular and Cellular Endocrinology. 321: 231-8. PMID 20223276 DOI: 10.1016/j.mce.2010.03.002  1
2010 Kwakkel J, Chassande O, van Beeren HC, Fliers E, Wiersinga WM, Boelen A. Thyroid hormone receptor {alpha} modulates lipopolysaccharide-induced changes in peripheral thyroid hormone metabolism. Endocrinology. 151: 1959-69. PMID 20194731 DOI: 10.1210/en.2009-1049  1
2010 Soeters MR, Huidekoper HH, Duran M, Ackermans MT, Endert E, Fliers E, Wijburg FA, Wanders RJ, Sauerwein HP, Serlie MJ. Extended metabolic evaluation of suspected symptomatic hypoglycemia: the prolonged fast and beyond. Metabolism: Clinical and Experimental. 59: 1543-50. PMID 20189609 DOI: 10.1016/j.metabol.2010.01.024  1
2010 Kalsbeek A, Fliers E, Hofman MA, Swaab DF, Buijs RM. Vasopressin and the output of the hypothalamic biological clock. Journal of Neuroendocrinology. 22: 362-72. PMID 20088910 DOI: 10.1111/j.1365-2826.2010.01956.x  1
2010 Yi CX, la Fleur SE, Fliers E, Kalsbeek A. The role of the autonomic nervous liver innervation in the control of energy metabolism. Biochimica Et Biophysica Acta. 1802: 416-31. PMID 20060897 DOI: 10.1016/j.bbadis.2010.01.006  1
2010 Fliers E, Klieverik LP, Kalsbeek A. Novel neural pathways for metabolic effects of thyroid hormone. Trends in Endocrinology and Metabolism: Tem. 21: 230-6. PMID 20005733 DOI: 10.1016/j.tem.2009.11.008  1
2010 Roelfsema F, Pereira AM, Adriaanse R, Endert E, Fliers E, Romijn JA, Veldhuis JD. Thyrotropin secretion in mild and severe primary hypothyroidism is distinguished by amplified burst mass and Basal secretion with increased spikiness and approximate entropy. The Journal of Clinical Endocrinology and Metabolism. 95: 928-34. PMID 19965923 DOI: 10.1210/jc.2009-1959  1
2010 Benhadi N, Fliers E, Visser TJ, Reitsma JB, Wiersinga WM. Pilot study on the assessment of the setpoint of the hypothalamus-pituitary-thyroid axis in healthy volunteers. European Journal of Endocrinology / European Federation of Endocrine Societies. 162: 323-9. PMID 19926783 DOI: 10.1530/EJE-09-0655  1
2010 Visser TJ, Fliers E. Thyroid Hormones Encyclopedia of Stress. 743-749. DOI: 10.1016/B978-012373947-6.00379-2  1
2009 Boelen A, Mikita J, Boiziau C, Chassande O, Fliers E, Petry KG. Type 3 deiodinase expression in inflammatory spinal cord lesions in rat experimental autoimmune encephalomyelitis. Thyroid : Official Journal of the American Thyroid Association. 19: 1401-6. PMID 19916870 DOI: 10.1089/thy.2009.0228  1
2009 Faneyte IF, Sanson RE, van Eeden S, Fliers E, Gouma DJ, van Dijkum EJ. [Patient with relapsed hyperparathyroidism and neck swelling]. Nederlands Tijdschrift Voor Geneeskunde. 153: B249. PMID 19857304  1
2009 Klieverik LP, Coomans CP, Endert E, Sauerwein HP, Havekes LM, Voshol PJ, Rensen PC, Romijn JA, Kalsbeek A, Fliers E. Thyroid hormone effects on whole-body energy homeostasis and tissue-specific fatty acid uptake in vivo. Endocrinology. 150: 5639-48. PMID 19854865 DOI: 10.1210/en.2009-0297  1
2009 Soeters MR, Lammers NM, Dubbelhuis PF, Ackermans M, Jonkers-Schuitema CF, Fliers E, Sauerwein HP, Aerts JM, Serlie MJ. Intermittent fasting does not affect whole-body glucose, lipid, or protein metabolism. The American Journal of Clinical Nutrition. 90: 1244-51. PMID 19776143 DOI: 10.3945/ajcn.2008.27327  1
2009 Roelfsema F, Pereira AM, Veldhuis JD, Adriaanse R, Endert E, Fliers E, Romijn JA. Thyrotropin secretion profiles are not different in men and women. The Journal of Clinical Endocrinology and Metabolism. 94: 3964-7. PMID 19773394 DOI: 10.1210/jc.2009-1155  1
2009 Mebis L, Debaveye Y, Ellger B, Derde S, Ververs EJ, Langouche L, Darras VM, Fliers E, Visser TJ, Van den Berghe G. Changes in the central component of the hypothalamus-pituitary-thyroid axis in a rabbit model of prolonged critical illness. Critical Care (London, England). 13: R147. PMID 19747372 DOI: 10.1186/cc8043  1
2009 van Bon AC, Benhadi N, Endert E, Fliers E, Wiersinga WM. Evaluation of endocrine tests. D: the prolonged fasting test for insulinoma. The Netherlands Journal of Medicine. 67: 274-8. PMID 19687521  1
2009 Kwakkel J, van Beeren HC, Ackermans MT, Platvoet-Ter Schiphorst MC, Fliers E, Wiersinga WM, Boelen A. Skeletal muscle deiodinase type 2 regulation during illness in mice. The Journal of Endocrinology. 203: 263-70. PMID 19656972 DOI: 10.1677/JOE-09-0118  1
2009 Yi CX, Serlie MJ, Ackermans MT, Foppen E, Buijs RM, Sauerwein HP, Fliers E, Kalsbeek A. A major role for perifornical orexin neurons in the control of glucose metabolism in rats. Diabetes. 58: 1998-2005. PMID 19592616 DOI: 10.2337/db09-0385  1
2009 Eskes SA, Tomasoa NB, Endert E, Geskus RB, Fliers E, Wiersinga WM. Establishment of reference values for endocrine tests. Part VII: growth hormone deficiency. The Netherlands Journal of Medicine. 67: 127-33. PMID 19581656  1
2009 Van Zaane B, Nur E, Squizzato A, Dekkers OM, Twickler MT, Fliers E, Gerdes VE, Büller HR, Brandjes DP. Hypercoagulable state in Cushing's syndrome: a systematic review. The Journal of Clinical Endocrinology and Metabolism. 94: 2743-50. PMID 19454584 DOI: 10.1210/jc.2009-0290  1
2009 Soeters MR, Sauerwein HP, Faas L, Smeenge M, Duran M, Wanders RJ, Ruiter AF, Ackermans MT, Fliers E, Houten SM, Serlie MJ. Effects of insulin on ketogenesis following fasting in lean and obese men. Obesity (Silver Spring, Md.). 17: 1326-31. PMID 19369940 DOI: 10.1038/oby.2008.678  1
2009 Klieverik LP, Janssen SF, van Riel A, Foppen E, Bisschop PH, Serlie MJ, Boelen A, Ackermans MT, Sauerwein HP, Fliers E, Kalsbeek A. Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver. Proceedings of the National Academy of Sciences of the United States of America. 106: 5966-71. PMID 19321430 DOI: 10.1073/pnas.0805355106  1
2009 Bisschop PH, Corssmit EP, Baas SJ, Serlie MJ, Endert E, Wiersinga WM, Fliers E. Evaluation of Endocrine Tests. C: glucagon and clonidine test in phaeochromocytoma. The Netherlands Journal of Medicine. 67: 91-5. PMID 19307679  1
2009 Boelen A, Kwakkel J, Chassande O, Fliers E. Thyroid hormone receptor β mediates acute illness-induced alterations in central thyroid hormone metabolism. Journal of Neuroendocrinology. 21: 465-72. PMID 19302190 DOI: 10.1111/j.1365-2826.2009.01863.x  1
2009 Heemstra KA, Soeters MR, Fliers E, Serlie MJ, Burggraaf J, van Doorn MB, van der Klaauw AA, Romijn JA, Smit JW, Corssmit EP, Visser TJ. Type 2 iodothyronine deiodinase in skeletal muscle: effects of hypothyroidism and fasting. The Journal of Clinical Endocrinology and Metabolism. 94: 2144-50. PMID 19293265 DOI: 10.1210/jc.2008-2520  1
2009 Klieverik LP, Foppen E, Ackermans MT, Serlie MJ, Sauerwein HP, Scanlan TS, Grandy DK, Fliers E, Kalsbeek A. Central effects of thyronamines on glucose metabolism in rats. The Journal of Endocrinology. 201: 377-86. PMID 19273499 DOI: 10.1677/JOE-09-0043  1
2009 Boelen A, Kwakkel J, Wieland CW, St Germain DL, Fliers E, Hernandez A. Impaired bacterial clearance in type 3 deiodinase-deficient mice infected with Streptococcus pneumoniae. Endocrinology. 150: 1984-90. PMID 19036878 DOI: 10.1210/en.2008-1133  1
2009 Heemstra KA, Hoftijzer HC, van der Deure WM, Peeters RP, Fliers E, Appelhof BC, Wiersinga WM, Corssmit EP, Visser TJ, Smit JW. Thr92Ala polymorphism in the type 2 deiodinase is not associated with T4 dose in athyroid patients or patients with Hashimoto thyroiditis. Clinical Endocrinology. 71: 279-83. PMID 19018782 DOI: 10.1111/j.1365-2265.2008.03474.x  1
2009 Soeters MR, Sauerwein HP, Duran M, Wanders RJ, Ackermans MT, Fliers E, Houten SM, Serlie MJ. Muscle acylcarnitines during short-term fasting in lean healthy men. Clinical Science (London, England : 1979). 116: 585-92. PMID 18945215 DOI: 10.1042/CS20080433  1
2009 Faneyte IF, Sanson RE, Van Eeden S, Fliers E, Gouma DJ, Nieveen Van Dijkum EJM. A female patient with a recurrence of hyperparathyroidism and a swelling in the neck | Een patiënte met een recidief van hyperparathyreoïdie en een zwelling in de hals Nederlands Tijdschrift Voor Geneeskunde. 153: 1872-1876.  1
2008 van Bon AC, Krudop W, van Eeden S, Schreuder MC, Nieveen van Dijkum EJ, Fliers E, Wiersinga WM. [Pain in the throat due to acute suppurative thyroiditis caused by Salmonella]. Nederlands Tijdschrift Voor Geneeskunde. 152: 2084-7. PMID 18837185  1
2008 Boelen A, Boorsma J, Kwakkel J, Wieland CW, Renckens R, Visser TJ, Fliers E, Wiersinga WM. Type 3 deiodinase is highly expressed in infiltrating neutrophilic granulocytes in response to acute bacterial infection. Thyroid : Official Journal of the American Thyroid Association. 18: 1095-103. PMID 18816180 DOI: 10.1089/thy.2008.0090  1
2008 Kalsbeek A, Foppen E, Schalij I, Van Heijningen C, van der Vliet J, Fliers E, Buijs RM. Circadian control of the daily plasma glucose rhythm: an interplay of GABA and glutamate. Plos One. 3: e3194. PMID 18791643 DOI: 10.1371/journal.pone.0003194  1
2008 Alkemade A, Visser TJ, Fliers E. Thyroid hormone signaling in the hypothalamus. Current Opinion in Endocrinology, Diabetes, and Obesity. 15: 453-8. PMID 18769219 DOI: 10.1097/MED.0b013e32830eb887  1
2008 Wiersinga WN, Fliers E. Determining the thyroid hormones T3 and T4 in the urine: An unreliable test for hypothyroidism [4] | Bepaling van schildklierhormoon (T3 en T4) in de urine: Weinig betrouwbare test voor de diagnose 'hypothyreoïdie' Nederlands Tijdschrift Voor Geneeskunde. 152: 1298-1299. PMID 18590068  1
2008 Ackermans MT, Klieverik LP, Endert E, Sauerwein HP, Kalsbeek A, Fliers E. Plasma insulin concentrations during a hyperinsulinaemic clamp: what do we measure? Annals of Clinical Biochemistry. 45: 429-30. PMID 18583632 DOI: 10.1258/acb.2008.007196  1
2008 van der Deure WM, Appelhof BC, Peeters RP, Wiersinga WM, Wekking EM, Huyser J, Schene AH, Tijssen JG, Hoogendijk WJ, Visser TJ, Fliers E. Polymorphisms in the brain-specific thyroid hormone transporter OATP1C1 are associated with fatigue and depression in hypothyroid patients. Clinical Endocrinology. 69: 804-11. PMID 18410547 DOI: 10.1111/j.1365-2265.2008.03267.x  1
2008 Michel MC, Fliers E, Van Noorden CJ. Dipeptidyl peptidase IV inhibitors in diabetes: more than inhibition of glucagon-like peptide-1 metabolism? Naunyn-Schmiedeberg's Archives of Pharmacology. 377: 205-7. PMID 18398599 DOI: 10.1007/s00210-008-0280-0  1
2008 Soeters MR, Sauerwein HP, Dubbelhuis PF, Groener JE, Ackermans MT, Fliers E, Aerts JM, Serlie MJ. Muscle adaptation to short-term fasting in healthy lean humans. The Journal of Clinical Endocrinology and Metabolism. 93: 2900-3. PMID 18397976 DOI: 10.1210/jc.2008-0250  1
2008 Boelen A, Wiersinga WM, Fliers E. Fasting-induced changes in the hypothalamus-pituitary-thyroid axis. Thyroid : Official Journal of the American Thyroid Association. 18: 123-9. PMID 18225975 DOI: 10.1089/thy.2007.0253  1
2008 Klieverik LP, Sauerwein HP, Ackermans MT, Boelen A, Kalsbeek A, Fliers E. Effects of thyrotoxicosis and selective hepatic autonomic denervation on hepatic glucose metabolism in rats. American Journal of Physiology. Endocrinology and Metabolism. 294: E513-20. PMID 18182466 DOI: 10.1152/ajpendo.00659.2007  1
2008 van Nimwegen LJ, Storosum JG, Blumer RM, Allick G, Venema HW, de Haan L, Becker H, van Amelsvoort T, Ackermans MT, Fliers E, Serlie MJ, Sauerwein HP. Hepatic insulin resistance in antipsychotic naive schizophrenic patients: stable isotope studies of glucose metabolism. The Journal of Clinical Endocrinology and Metabolism. 93: 572-7. PMID 18029467 DOI: 10.1210/jc.2007-1167  1
2007 Wiersinga WM, Fliers E. [Determining the thyroid hormones T3 and T4 in the urine: an unreliable test for hypothyroidism]. Nederlands Tijdschrift Voor Geneeskunde. 151: 2813-5. PMID 18237046  1
2007 Kalsbeek A, Kreier F, Fliers E, Sauerwein HP, Romijn JA, Buijs RM. Minireview: Circadian control of metabolism by the suprachiasmatic nuclei. Endocrinology. 148: 5635-9. PMID 17901232 DOI: 10.1210/en.2007-0776  1
2007 Soeters MR, Sauerwein HP, Groener JE, Aerts JM, Ackermans MT, Glatz JF, Fliers E, Serlie MJ. Gender-related differences in the metabolic response to fasting. The Journal of Clinical Endocrinology and Metabolism. 92: 3646-52. PMID 17566089 DOI: 10.1210/jc.2007-0552  1
2007 Monajemi H, Stroes E, Hegele RA, Fliers E. Inherited lipodystrophies and the metabolic syndrome. Clinical Endocrinology. 67: 479-84. PMID 17561981 DOI: 10.1111/j.1365-2265.2007.02906.x  1
2007 Thijssen-Timmer DC, Peeters RP, Wouters P, Weekers F, Visser TJ, Fliers E, Wiersinga WM, Bakker O, Van Den Berghe G. Thyroid hormone receptor isoform expression in livers of critically ill patients. Thyroid : Official Journal of the American Thyroid Association. 17: 105-12. PMID 17316111 DOI: 10.1089/thy.2006.0164  1
2007 Serlie MJ, Meijer AJ, Groener JE, Duran M, Endert E, Fliers E, Aerts JM, Sauerwein HP. Short-term manipulation of plasma free fatty acids does not change skeletal muscle concentrations of ceramide and glucosylceramide in lean and overweight subjects. The Journal of Clinical Endocrinology and Metabolism. 92: 1524-9. PMID 17264178 DOI: 10.1210/jc.2006-2347  1
2007 Kreier F, Kalsbeek A, Sauerwein HP, Fliers E, Romijn JA, Buijs RM. "Diabetes of the elderly" and type 2 diabetes in younger patients: possible role of the biological clock. Experimental Gerontology. 42: 22-7. PMID 17049784 DOI: 10.1016/j.exger.2006.07.004  1
2006 Boelen A, Kwakkel J, Wiersinga WM, Fliers E. Chronic local inflammation in mice results in decreased TRH and type 3 deiodinase mRNA expression in the hypothalamic paraventricular nucleus independently of diminished food intake. The Journal of Endocrinology. 191: 707-14. PMID 17170227 DOI: 10.1677/joe.1.07056  1
2006 Brouwer JP, Appelhof BC, van Rossum EF, Koper JW, Fliers E, Huyser J, Schene AH, Tijssen JG, Van Dyck R, Lamberts SW, Wiersinga WM, Hoogendijk WJ. Prediction of treatment response by HPA-axis and glucocorticoid receptor polymorphisms in major depression. Psychoneuroendocrinology. 31: 1154-63. PMID 17034955 DOI: 10.1016/j.psyneuen.2006.08.001  1
2006 de Graaff MJ, Buijs RM, Hoekstra JB, Fliers E, Holleman F. [Melatonin: physiological and pathophysiological aspects and possible applications]. Nederlands Tijdschrift Voor Geneeskunde. 150: 1971-5. PMID 17002185  1
2006 Endert E, van Rooden M, Fliers E, Prummel MF, Wiersinga WM. Establishment of reference values for endocrine tests--part V: acromegaly. The Netherlands Journal of Medicine. 64: 230-5. PMID 16929084  0.72
2006 Boelen A, Kwakkel J, Vos XG, Wiersinga WM, Fliers E. Differential effects of leptin and refeeding on the fasting-induced decrease of pituitary type 2 deiodinase and thyroid hormone receptor beta2 mRNA expression in mice. The Journal of Endocrinology. 190: 537-44. PMID 16899586 DOI: 10.1677/joe.1.06872  0.72
2006 van Wezel HB, Zuurbier CJ, de Jonge E, van Dam EW, van Dijk J, Endert E, de Mol BA, Fliers E. Differential effects of a perioperative hyperinsulinemic normoglycemic clamp on the neurohumoral stress response during coronary artery surgery. The Journal of Clinical Endocrinology and Metabolism. 91: 4144-53. PMID 16895948 DOI: 10.1210/jc.2006-1199  0.64
2006 Fliers E, Alkemade A, Wiersinga WM, Swaab DF. Hypothalamic thyroid hormone feedback in health and disease. Progress in Brain Research. 153: 189-207. PMID 16876576 DOI: 10.1016/S0079-6123(06)53011-0  1
2006 Bisschop PH, Toorians AW, Endert E, Wiersinga WM, Gooren LJ, Fliers E. The effects of sex-steroid administration on the pituitary-thyroid axis in transsexuals. European Journal of Endocrinology / European Federation of Endocrine Societies. 155: 11-6. PMID 16793944 DOI: 10.1530/eje.1.02192  0.76
2006 Pitteloud N, Meysing A, Quinton R, Acierno JS, Dwyer AA, Plummer L, Fliers E, Boepple P, Hayes F, Seminara S, Hughes VA, Ma J, Bouloux P, Mohammadi M, Crowley WF. Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes. Molecular and Cellular Endocrinology. 254: 60-9. PMID 16764984 DOI: 10.1016/j.mce.2006.04.021  1
2006 Brouwer JP, Appelhof BC, Peeters RP, Hoogendijk WJ, Huyser J, Schene AH, Tijssen JG, Van Dyck R, Visser TJ, Wiersinga WM, Fliers E. Thyrotropin, but not a polymorphism in type II deiodinase, predicts response to paroxetine in major depression. European Journal of Endocrinology / European Federation of Endocrine Societies. 154: 819-25. PMID 16728541 DOI: 10.1530/eje.1.02155  1
2006 Fliers E, Unmehopa UA, Alkemade A. Functional neuroanatomy of thyroid hormone feedback in the human hypothalamus and pituitary gland. Molecular and Cellular Endocrinology. 251: 1-8. PMID 16707210 DOI: 10.1016/j.mce.2006.03.042  0.84
2006 Alkemade A, Friesema EC, Kuiper GG, Wiersinga WM, Swaab DF, Visser TJ, Fliers E. Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary. European Journal of Endocrinology / European Federation of Endocrine Societies. 154: 491-500. PMID 16498064 DOI: 10.1530/eje.1.02111  1
2006 Peeters RP, Debaveye Y, Fliers E, Visser TJ. Changes within the thyroid axis during critical illness. Critical Care Clinics. 22: 41-55, vi. PMID 16399019 DOI: 10.1016/j.ccc.2005.08.006  0.68
2006 Appelhof BC, Huyser J, Verweij M, Brouwer JP, van Dyck R, Fliers E, Hoogendijk WJ, Tijssen JG, Wiersinga WM, Schene AH. Glucocorticoids and relapse of major depression (dexamethasone/corticotropin-releasing hormone test in relation to relapse of major depression). Biological Psychiatry. 59: 696-701. PMID 16368077 DOI: 10.1016/j.biopsych.2005.09.008  1
2006 Kreier F, Kap YS, Mettenleiter TC, van Heijningen C, van der Vliet J, Kalsbeek A, Sauerwein HP, Fliers E, Romijn JA, Buijs RM. Tracing from fat tissue, liver, and pancreas: a neuroanatomical framework for the role of the brain in type 2 diabetes. Endocrinology. 147: 1140-7. PMID 16339209 DOI: 10.1210/en.2005-0667  1
2006 Holleman F, De Graaff MJ, Buijs RM, Hoekstra JBL, Fliers E. Melatonin: Physiological and pathophysiological aspects and possible applications | Melatonine: Fysiologische en pathofysiologische aspecten en mogelijke toepassingen Nederlands Tijdschrift Voor Geneeskunde. 150: 2787.  1
2005 Endert E, Ouwehand A, Fliers E, Prummel MF, Wiersinga WM. Establishment of reference values for endocrine tests. Part IV: Adrenal insufficiency. The Netherlands Journal of Medicine. 63: 435-43. PMID 16397312  0.72
2005 Wekking EM, Appelhof BC, Fliers E, Schene AH, Huyser J, Tijssen JG, Wiersinga WM. Cognitive functioning and well-being in euthyroid patients on thyroxine replacement therapy for primary hypothyroidism. European Journal of Endocrinology / European Federation of Endocrine Societies. 153: 747-53. PMID 16322379 DOI: 10.1530/eje.1.02025  0.72
2005 Holleman F, Endert E, Prummel MF, van Vessem-Timmermans M, Wiersinga WM, Fliers E. Evaluation of endocrine tests. B: screening for hypercortisolism. The Netherlands Journal of Medicine. 63: 348-53. PMID 16244382  0.72
2005 Appelhof BC, Peeters RP, Wiersinga WM, Visser TJ, Wekking EM, Huyser J, Schene AH, Tijssen JG, Hoogendijk WJ, Fliers E. Polymorphisms in type 2 deiodinase are not associated with well-being, neurocognitive functioning, and preference for combined thyroxine/3,5,3'-triiodothyronine therapy. The Journal of Clinical Endocrinology and Metabolism. 90: 6296-9. PMID 16144953 DOI: 10.1210/jc.2005-0451  0.72
2005 Romijn JA, Fliers E. Sympathetic and parasympathetic innervation of adipose tissue: metabolic implications. Current Opinion in Clinical Nutrition and Metabolic Care. 8: 440-4. PMID 15930971  0.68
2005 Alkemade A, Friesema EC, Unmehopa UA, Fabriek BO, Kuiper GG, Leonard JL, Wiersinga WM, Swaab DF, Visser TJ, Fliers E. Neuroanatomical pathways for thyroid hormone feedback in the human hypothalamus. The Journal of Clinical Endocrinology and Metabolism. 90: 4322-34. PMID 15840737 DOI: 10.1210/jc.2004-2567  1
2005 Brouwer JP, Appelhof BC, Hoogendijk WJ, Huyser J, Endert E, Zuketto C, Schene AH, Tijssen JG, Van Dyck R, Wiersinga WM, Fliers E. Thyroid and adrenal axis in major depression: a controlled study in outpatients. European Journal of Endocrinology / European Federation of Endocrine Societies. 152: 185-91. PMID 15745924 DOI: 10.1530/eje.1.01828  1
2005 Appelhof BC, Fliers E, Wekking EM, Schene AH, Huyser J, Tijssen JG, Endert E, van Weert HC, Wiersinga WM. Combined therapy with levothyroxine and liothyronine in two ratios, compared with levothyroxine monotherapy in primary hypothyroidism: a double-blind, randomized, controlled clinical trial. The Journal of Clinical Endocrinology and Metabolism. 90: 2666-74. PMID 15705921 DOI: 10.1210/jc.2004-2111  0.72
2005 Alkemade A, Vuijst CL, Unmehopa UA, Bakker O, Vennström B, Wiersinga WM, Swaab DF, Fliers E. Thyroid hormone receptor expression in the human hypothalamus and anterior pituitary. The Journal of Clinical Endocrinology and Metabolism. 90: 904-12. PMID 15562027 DOI: 10.1210/jc.2004-0474  1
2005 Kalsbeek A, Buijs RM, van Schaik R, Kaptein E, Visser TJ, Doulabi BZ, Fliers E. Daily variations in type II iodothyronine deiodinase activity in the rat brain as controlled by the biological clock. Endocrinology. 146: 1418-27. PMID 15550511 DOI: 10.1210/en.2004-0763  1
2005 Alkemade A, Unmehopa UA, Wiersinga WM, Swaab DF, Fliers E. Glucocorticoids decrease thyrotropin-releasing hormone messenger ribonucleic acid expression in the paraventricular nucleus of the human hypothalamus. The Journal of Clinical Endocrinology and Metabolism. 90: 323-7. PMID 15509645 DOI: 10.1210/jc.2004-1430  1
2004 Appelhof BC, Brouwer JP, van Dyck R, Fliers E, Hoogendijk WJ, Huyser J, Schene AH, Tijssen JG, Wiersinga WM. Triiodothyronine addition to paroxetine in the treatment of major depressive disorder. The Journal of Clinical Endocrinology and Metabolism. 89: 6271-6. PMID 15579788 DOI: 10.1210/jc.2004-1147  1
2004 Boelen A, Kwakkel J, Thijssen-Timmer DC, Alkemade A, Fliers E, Wiersinga WM. Simultaneous changes in central and peripheral components of the hypothalamus-pituitary-thyroid axis in lipopolysaccharide-induced acute illness in mice. The Journal of Endocrinology. 182: 315-23. PMID 15283692  0.84
2004 Van Someren EJ, Swart-Heikens J, Endert E, Bisschop PH, Swaab DF, Bakker PJ, Romijn JA, Fliers E. Long-term effects of cranial irradiation for childhood malignancy on sleep in adulthood. European Journal of Endocrinology / European Federation of Endocrine Societies. 150: 503-10. PMID 15080780  1
2004 Zandieh Doulabi B, Platvoet-Ter Schiphorst M, Kalsbeek A, Fliers E, Bakker O, Wiersinga WM. Diurnal variation in rat liver thyroid hormone receptor (TR)-alpha messenger ribonucleic acid (mRNA) is dependent on the biological clock in the suprachiasmatic nucleus, whereas diurnal variation of TR beta 1 mRNA is modified by food intake. Endocrinology. 145: 1284-9. PMID 14657007 DOI: 10.1210/en.2003-0791  1
2003 Fliers E, Sauerwein HP, Romijn JA, Reiss P, van der Valk M, Kalsbeek A, Kreier F, Buijs RM. HIV-associated adipose redistribution syndrome as a selective autonomic neuropathy. Lancet. 362: 1758-60. PMID 14643128 DOI: 10.1016/S0140-6736(03)14858-1  1
2003 Kreier F, Kalsbeek A, Ruiter M, Yilmaz A, Romijn JA, Sauerwein HP, Fliers E, Buijs RM. Central nervous determination of food storage--a daily switch from conservation to expenditure: implications for the metabolic syndrome. European Journal of Pharmacology. 480: 51-65. PMID 14623350 DOI: 10.1016/j.ejphar.2003.08.092  1
2003 Fliers E, Kreier F, Voshol PJ, Havekes LM, Sauerwein HP, Kalsbeek A, Buijs RM, Romijn JA. White adipose tissue: getting nervous. Journal of Neuroendocrinology. 15: 1005-10. PMID 14622429 DOI: 10.1046/j.1365-2826.2003.01096.x  1
2003 Kreier F, Yilmaz A, Kalsbeek A, Romijn JA, Sauerwein HP, Fliers E, Buijs RM. Hypothesis: shifting the equilibrium from activity to food leads to autonomic unbalance and the metabolic syndrome. Diabetes. 52: 2652-6. PMID 14578282 DOI: 10.2337/diabetes.52.11.2652  1
2003 Alkemade A, Unmehopa UA, Brouwer JP, Hoogendijk WJ, Wiersinga WM, Swaab DF, Fliers E. Decreased thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus of patients with major depression. Molecular Psychiatry. 8: 838-9. PMID 14515134 DOI: 10.1038/sj.mp.4001364  1
2003 Fliers E, Wiersinga WM. [Screening pregnant women for hypothyroidism: as yet only in high risk groups]. Nederlands Tijdschrift Voor Geneeskunde. 147: 1159-61. PMID 12845834  0.72
2003 Fliers E, Wiersinga WM. Myxedema coma. Reviews in Endocrine & Metabolic Disorders. 4: 137-41. PMID 12766541  0.72
2003 Le Moli R, Endert E, Fliers E, Prummel MF, Wiersinga WM. Evaluation of endocrine tests. A: the TRH test in patients with hyperprolactinaemia. The Netherlands Journal of Medicine. 61: 44-8. PMID 12735420  0.72
2003 Baas SJ, Endert E, Fliers E, Prummel MF, Wiersinga WM. Establishment of reference values for endocrine tests. III: Primary aldosteronism. The Netherlands Journal of Medicine. 61: 37-43. PMID 12735419  0.72
2002 Fliers E, Romijn JA, Sauerwein HP, Kalsbeek A, Kreier F, Buijs RM. [Adipose tissue: an innervated endocrine gland]. Nederlands Tijdschrift Voor Geneeskunde. 146: 1976-9. PMID 12420422  1
2002 Scheer FA, Van Paassen B, Van Montfrans GA, Fliers E, Van Someren EJ, Van Heerikhuize JJ, Buijs RM. Human basal cortisol levels are increased in hospital compared to home setting. Neuroscience Letters. 333: 79-82. PMID 12419485 DOI: 10.1016/S0304-3940(02)00988-6  1
2002 Kreier F, Fliers E, Voshol PJ, Van Eden CG, Havekes LM, Kalsbeek A, Van Heijningen CL, Sluiter AA, Mettenleiter TC, Romijn JA, Sauerwein HP, Buijs RM. Selective parasympathetic innervation of subcutaneous and intra-abdominal fat--functional implications. The Journal of Clinical Investigation. 110: 1243-50. PMID 12417562 DOI: 10.1172/JCI15736  1
2002 Panayotacopoulou MT, Malidelis YI, Fliers E, Bouras C, Ravid R, Swaab DF. Increased expression of tyrosine hydroxylase immunoreactivity in paraventricular and supraoptic neurons in illnesses with prolonged osmotic or nonosmotic stimulation of vasopressin release. Neuroendocrinology. 76: 254-66. PMID 12411742  1
2002 Zandieh Doulabi B, Platvoet-ter Schiphorst M, van Beeren HC, Labruyere WT, Lamers WH, Fliers E, Bakker O, Wiersinga WM. TR(beta)1 protein is preferentially expressed in the pericentral zone of rat liver and exhibits marked diurnal variation. Endocrinology. 143: 979-84. PMID 11861522 DOI: 10.1210/endo.143.3.8706  0.72
2001 Fliers E, Alkemade A, Wiersinga WM. The hypothalamic-pituitary-thyroid axis in critical illness. Best Practice & Research. Clinical Endocrinology & Metabolism. 15: 453-64. PMID 11800517 DOI: 10.1053/beem.2001.0163  0.84
2001 Kalsbeek A, Fliers E, Romijn JA, La Fleur SE, Wortel J, Bakker O, Endert E, Buijs RM. The suprachiasmatic nucleus generates the diurnal changes in plasma leptin levels. Endocrinology. 142: 2677-85. PMID 11356719 DOI: 10.1210/endo.142.6.8197  1
2001 Fliers E, Unmehopa UA, Manniesing S, Vuijst CL, Wiersinga WM, Swaab DF. Decreased neuropeptide Y (NPY) expression in the infundibular nucleus of patients with nonthyroidal illness. Peptides. 22: 459-65. PMID 11287102  1
2001 Diekman MJ, Zandieh Doulabi B, Platvoet-Ter Schiphorst M, Fliers E, Bakker O, Wiersinga WM. The biological relevance of thyroid hormone receptors in immortalized human umbilical vein endothelial cells. The Journal of Endocrinology. 168: 427-33. PMID 11241174  0.72
2000 Swaab DF, Fliers E, Hoogendijk WJ, Veltman DJ, Zhou JN. Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression. Progress in Brain Research. 126: 369-96. PMID 11105658 DOI: 10.1016/S0079-6123(00)26025-1  1
2000 Kalsbeek A, Fliers E, Franke AN, Wortel J, Buijs RM. Functional connections between the suprachiasmatic nucleus and the thyroid gland as revealed by lesioning and viral tracing techniques in the rat. Endocrinology. 141: 3832-41. PMID 11014240 DOI: 10.1210/endo.141.10.7709  1
2000 Verberne HJ, Fliers E, Prummel MF, Stam J, Brandjes DP, Wiersinga WM. Thyrotoxicosis as a predisposing factor for cerebral venous thrombosis. Thyroid : Official Journal of the American Thyroid Association. 10: 607-10. PMID 10958314  0.72
2000 Heikens J, Ubbink MC, van der Pal HP, Bakker PJ, Fliers E, Smilde TJ, Kastelein JJ, Trip MD. Long term survivors of childhood brain cancer have an increased risk for cardiovascular disease. Cancer. 88: 2116-21. PMID 10813724 DOI: 10.1002/(SICI)1097-0142(20000501)88:9<2116::AID-CNCR18>3.0.CO;2-U  0.44
1999 Le Moli R, Endert E, Fliers E, Mulder T, Prummel MF, Romijn JA, Wiersinga WM. Establishment of reference values for endocrine tests. II: Hyperprolactinemia. The Netherlands Journal of Medicine. 55: 71-5. PMID 10474275  0.72
1998 Heikens J, Michiels EM, Behrendt H, Endert E, Bakker PJ, Fliers E. Long-term neuro-endocrine sequelae after treatment for childhood medulloblastoma. European Journal of Cancer (Oxford, England : 1990). 34: 1592-7. PMID 9893634  0.64
1998 Alings AM, Fliers E, de Herder WW, Hofland LJ, Sluiter HE, Links TP, van der Hoeven JH, Wiersinga WM. A thyrotropin-secreting pituitary adenoma as a cause of thyrotoxic periodic paralysis. Journal of Endocrinological Investigation. 21: 703-6. PMID 9854688  0.72
1998 Fliers E, Wiersinga WM, Swaab DF. Physiological and pathophysiological aspects of thyrotropin-releasing hormone gene expression in the human hypothalamus. Thyroid : Official Journal of the American Thyroid Association. 8: 921-8. PMID 9827660  1
1998 de Bos Kuil MJ, Endert E, Fliers E, Prummel MF, Romijn JA, Wiersinga WM. Establishment of reference values for endocrine tests. I: Cushing's syndrome. The Netherlands Journal of Medicine. 53: 153-63. PMID 9825640  0.72
1997 Fliers E, Guldenaar SE, Wiersinga WM, Swaab DF. Decreased hypothalamic thyrotropin-releasing hormone gene expression in patients with nonthyroidal illness. The Journal of Clinical Endocrinology and Metabolism. 82: 4032-6. PMID 9398708 DOI: 10.1210/jcem.82.12.4404  1
1996 Guldenaar SE, Veldkamp B, Bakker O, Wiersinga WM, Swaab DF, Fliers E. Thyrotropin-releasing hormone gene expression in the human hypothalamus. Brain Research. 743: 93-101. PMID 9017235  1
1995 Heikens J, Fliers E, Endert E, Ackermans M, van Montfrans G. Liquorice-induced hypertension--a new understanding of an old disease: case report and brief review. The Netherlands Journal of Medicine. 47: 230-4. PMID 8544895  0.64
1994 Fliers E, Noppen NW, Wiersinga WM, Visser TJ, Swaab DF. Distribution of thyrotropin-releasing hormone (TRH)-containing cells and fibers in the human hypothalamus. The Journal of Comparative Neurology. 350: 311-23. PMID 7884045 DOI: 10.1002/cne.903500213  1
1990 Goudsmit E, Hofman MA, Fliers E, Swaab DF. The supraoptic and paraventricular nuclei of the human hypothalamus in relation to sex, age and Alzheimer's disease. Neurobiology of Aging. 11: 529-36. PMID 2234284  1
1988 Hofman MA, Fliers E, Goudsmit E, Swaab DF. Morphometric analysis of the suprachiasmatic and paraventricular nuclei in the human brain: sex differences and age-dependent changes. Journal of Anatomy. 160: 127-43. PMID 3253251  1
1988 Goudsmit E, Fliers E, Swaab DF. Vasopressin and oxytocin excretion in the Brown-Norway rat in relation to aging, water metabolism and testosterone. Mechanisms of Ageing and Development. 44: 241-52. PMID 3216721  1
1988 Goudsmit E, Fliers E, Swaab DF. Testosterone supplementation restores vasopressin innervation in the senescent rat brain. Brain Research. 473: 306-13. PMID 3069184  1
1987 Ravid R, Fliers E, Swaab DF, Zurcher C. Changes in vasopressin and testosterone in the senescent brown-Norway (BN/BiRij) rat. Gerontology. 33: 87-98. PMID 2956158  1
1986 Swaab DF, Hofman MA, Fliers E. [Sex differentiation of the human brain]. Nederlands Tijdschrift Voor Geneeskunde. 130: 106-10. PMID 3951597  1
1986 Swaab DF, Fliers E, van Gool WA. Immunocytochemical localization of vasopressin in the human brain; its possible consequences for therapeutic strategies in aging and dementia. Progress in Brain Research. 65: 105-13. PMID 3786790 DOI: 10.1016/S0079-6123(08)60645-7  1
1986 Fliers E, Guldenaar SE, van de Wal N, Swaab DF. Extrahypothalamic vasopressin and oxytocin in the human brain; presence of vasopressin cells in the bed nucleus of the stria terminalis. Brain Research. 375: 363-7. PMID 3524745  1
1986 Ravid R, Swaab DF, Fliers E, Hoogendijk JE. [Increased vasopressin production in senescence and dementia]. Tijdschrift Voor Gerontologie En Geriatrie. 17: 136-40. PMID 2945301  1
1986 Swaab DF, Fliers E. Clinical strategies in the treatment of Alzheimer's disease. Progress in Brain Research. 70: 413-27. PMID 2883704  1
1986 Fliers E, Swaab DF. Neuropeptide changes in aging and Alzheimer's disease. Progress in Brain Research. 70: 141-52. PMID 2883702  1
1985 Fliers E, Swaab DF, Pool CW, Verwer RW. The vasopressin and oxytocin neurons in the human supraoptic and paraventricular nucleus; changes with aging and in senile dementia. Brain Research. 342: 45-53. PMID 4041817  1
1985 Swaab DF, Fliers E, Partiman TS. The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia. Brain Research. 342: 37-44. PMID 4041816  1
1985 Swaab DF, Fliers E. A sexually dimorphic nucleus in the human brain. Science (New York, N.Y.). 228: 1112-5. PMID 3992248  1
1985 Swaab DF, Fliers E, Fisser B. The vasopressin containing neurons in the human brain; changes during ageing and senile dementia. British Journal of Clinical Practice. Supplement. 39: 7-10. PMID 3929817  1
1985 Fliers E, De Vries GJ, Swaab DF. Changes with aging in the vasopressin and oxytocin innervation of the rat brain. Brain Research. 348: 1-8. PMID 3904923  1
1985 Hoogendijk JE, Fliers E, Swaab DF, Verwer RW. Activation of vasopressin neurons in the human supraoptic and paraventricular nucleus in senescence and senile dementia. Journal of the Neurological Sciences. 69: 291-9. PMID 3897463  1
1983 Fliers E, Swaab DF. Activation of vasopressinergic and oxytocinergic neurons during aging in the Wistar rat. Peptides. 4: 165-70. PMID 6622286  1
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