Jean-Pierre Changeux - Publications

Affiliations: 
Institut Pasteur, Paris, Paris, France 
Area:
Molecular Neurobiology

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Year Citation  Score
2017 Koukouli F, Rooy M, Tziotis D, Sailor KA, O'Neill HC, Levenga J, Witte M, Nilges M, Changeux JP, Hoeffer CA, Stitzel JA, Gutkin BS, DiGregorio DA, Maskos U. Nicotine reverses hypofrontality in animal models of addiction and schizophrenia. Nature Medicine. PMID 28112735 DOI: 10.1038/nm.4274  0.68
2016 Koukouli F, Rooy M, Changeux JP, Maskos U. Nicotinic receptors in mouse prefrontal cortex modulate ultraslow fluctuations related to conscious processing. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911815 DOI: 10.1073/pnas.1614417113  0.52
2016 Edelstein SJ, Changeux JP. Biased Allostery. Biophysical Journal. 111: 902-8. PMID 27602718 DOI: 10.1016/j.bpj.2016.07.044  1
2015 Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, ... ... Changeux JP, et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine. 7: 287ra72. PMID 25972004 DOI: 10.1126/scitranslmed.3009986  1
2015 Changeux JP, Corringer PJ, Maskos U. The nicotinic acetylcholine receptor: From molecular biology to cognition. Neuropharmacology. 96: 135-6. PMID 25842243 DOI: 10.1016/j.neuropharm.2015.03.024  1
2015 Cecchini M, Changeux JP. The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation. Neuropharmacology. 96: 137-49. PMID 25529272 DOI: 10.1016/j.neuropharm.2014.12.006  1
2014 Changeux JP. Protein dynamics and the allosteric transitions of pentameric receptor channels. Biophysical Reviews. 6: 311-321. PMID 25505495 DOI: 10.1007/s12551-014-0149-z  1
2014 Devesa I, Ferrándiz-Huertas C, Mathivanan S, Wolf C, Luján R, Changeux JP, Ferrer-Montiel A. αCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 18345-50. PMID 25489075 DOI: 10.1073/pnas.1420252111  1
2014 Taly A, Hénin J, Changeux JP, Cecchini M. Allosteric regulation of pentameric ligand-gated ion channels: an emerging mechanistic perspective. Channels (Austin, Tex.). 8: 350-60. PMID 25478624 DOI: 10.4161/chan.29444  1
2014 Christopoulos A, Changeux JP, Catterall WA, Fabbro D, Burris TP, Cidlowski JA, Olsen RW, Peters JA, Neubig RR, Pin JP, Sexton PM, Kenakin TP, Ehlert FJ, Spedding M, Langmead CJ. International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands. Pharmacological Reviews. 66: 918-47. PMID 25026896 DOI: 10.1124/pr.114.008862  1
2014 Kaczanowska K, Harel M, Radić Z, Changeux JP, Finn MG, Taylor P. Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein. Proceedings of the National Academy of Sciences of the United States of America. 111: 10749-54. PMID 25006260 DOI: 10.1073/pnas.1410992111  1
2014 Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz À, Haouz A, Changeux JP, Corringer PJ, Delarue M. Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 966-71. PMID 24367074 DOI: 10.1073/pnas.1314997111  1
2013 Changeux JP. 50 years of allosteric interactions: the twists and turns of the models. Nature Reviews. Molecular Cell Biology. 14: 819-29. PMID 24150612 DOI: 10.1038/nrm3695  1
2013 Prevost MS, Moraga-Cid G, Van Renterghem C, Edelstein SJ, Changeux JP, Corringer PJ. Intermediate closed state for glycine receptor function revealed by cysteine cross-linking. Proceedings of the National Academy of Sciences of the United States of America. 110: 17113-8. PMID 24085847 DOI: 10.1073/pnas.1317009110  1
2013 Changeux JP. The concept of allosteric modulation: an overview. Drug Discovery Today. Technologies. 10: e223-8. PMID 24050272 DOI: 10.1016/j.ddtec.2012.07.007  1
2013 Calimet N, Simoes M, Changeux JP, Karplus M, Taly A, Cecchini M. A gating mechanism of pentameric ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 110: E3987-96. PMID 24043807 DOI: 10.1073/pnas.1313785110  1
2013 Changeux JP. The concept of allosteric interaction and its consequences for the chemistry of the brain. The Journal of Biological Chemistry. 288: 26969-86. PMID 23878193 DOI: 10.1074/jbc.X113.503375  1
2013 Changeux JP. The origins of allostery: from personal memories to material for the future. Journal of Molecular Biology. 425: 1396-406. PMID 23523086 DOI: 10.1016/j.jmb.2013.02.033  1
2013 Rømer Thomsen K, Joensson M, Lou HC, Møller A, Gross J, Kringelbach ML, Changeux JP. Altered paralimbic interaction in behavioral addiction. Proceedings of the National Academy of Sciences of the United States of America. 110: 4744-9. PMID 23487797 DOI: 10.1073/pnas.1302374110  1
2013 Tsigelny IF, Kouznetsova VL, Baitaluk M, Changeux JP. A hierarchical coherent-gene-group model for brain development. Genes, Brain, and Behavior. 12: 147-65. PMID 23173912 DOI: 10.1111/gbb.12005  1
2013 Tolu S, Eddine R, Marti F, David V, Graupner M, Pons S, Baudonnat M, Husson M, Besson M, Reperant C, Zemdegs J, Pagès C, Hay YA, Lambolez B, Caboche J, ... ... Changeux JP, et al. Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement. Molecular Psychiatry. 18: 382-93. PMID 22751493 DOI: 10.1038/mp.2012.83  1
2013 Changeux JP. Neuroscience & philosophy: An exchange New York Review of Books. 60.  1
2012 Changeux JP. The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily. The Journal of Biological Chemistry. 287: 40207-15. PMID 23038257 DOI: 10.1074/jbc.R112.407668  1
2012 Changeux JP. Conscious processing: implications for general anesthesia. Current Opinion in Anaesthesiology. 25: 397-404. PMID 22699320 DOI: 10.1097/ACO.0b013e32835561de  1
2012 Corringer PJ, Poitevin F, Prevost MS, Sauguet L, Delarue M, Changeux JP. Structure and pharmacology of pentameric receptor channels: from bacteria to brain. Structure (London, England : 1993). 20: 941-56. PMID 22681900 DOI: 10.1016/j.str.2012.05.003  1
2012 Wacongne C, Changeux JP, Dehaene S. A neuronal model of predictive coding accounting for the mismatch negativity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3665-78. PMID 22423089 DOI: 10.1523/JNEUROSCI.5003-11.2012  1
2012 Changeux JP. Allostery and the Monod-Wyman-Changeux model after 50 years. Annual Review of Biophysics. 41: 103-33. PMID 22224598 DOI: 10.1146/annurev-biophys-050511-102222  1
2012 Granon S, Changeux JP. Deciding between conflicting motivations: what mice make of their prefrontal cortex. Behavioural Brain Research. 229: 419-26. PMID 22108342 DOI: 10.1016/j.bbr.2011.11.011  1
2012 Besson M, David V, Baudonnat M, Cazala P, Guilloux JP, Reperant C, Cloez-Tayarani I, Changeux JP, Gardier AM, Granon S. Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. Psychopharmacology. 220: 1-14. PMID 21901321 DOI: 10.1007/s00213-011-2422-1  0.72
2012 Bourgeois JP, Meas-Yeadid V, Lesourd AM, Faure P, Pons S, Maskos U, Changeux JP, Olivo-Marin JC, Granon S. Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment. Cerebral Cortex (New York, N.Y. : 1991). 22: 1007-15. PMID 21810785 DOI: 10.1093/cercor/bhr159  1
2012 Changeux JP. Beauty in the brain: For a neuroscience of art Rendiconti Lincei. 23: 315-320. DOI: 10.1007/s12210-012-0192-2  1
2012 Changeux JP, Garey L. The good, the true, and the beautiful: A neuronal approach The Good, the True, and the Beautiful: a Neuronal Approach. 1-386.  1
2011 Changeux JP, Edelstein S. Conformational selection or induced fit? 50 years of debate resolved. F1000 Biology Reports. 3: 19. PMID 21941598 DOI: 10.3410/B3-19  1
2011 Changeux JP, Lou HC. Emergent pharmacology of conscious experience: new perspectives in substance addiction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2098-108. PMID 21719514 DOI: 10.1096/fj.11-0702ufm  1
2011 Changeux JP. 50th anniversary of the word "allosteric". Protein Science : a Publication of the Protein Society. 20: 1119-24. PMID 21574197 DOI: 10.1002/pro.658  1
2011 Dehaene S, Changeux JP. Experimental and theoretical approaches to conscious processing. Neuron. 70: 200-27. PMID 21521609 DOI: 10.1016/j.neuron.2011.03.018  1
2011 Exley R, Maubourguet N, David V, Eddine R, Evrard A, Pons S, Marti F, Threlfell S, Cazala P, McIntosh JM, Changeux JP, Maskos U, Cragg SJ, Faure P. Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Proceedings of the National Academy of Sciences of the United States of America. 108: 7577-82. PMID 21502501 DOI: 10.1073/pnas.1103000108  1
2011 Avale ME, Chabout J, Pons S, Serreau P, De Chaumont F, Olivo-Marin JC, Bourgeois JP, Maskos U, Changeux JP, Granon S. Prefrontal nicotinic receptors control novel social interaction between mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2145-55. PMID 21402717 DOI: 10.1096/fj.10-178558  1
2011 Lykhmus O, Koval L, Skok M, Zouridakis M, Zisimopoulou P, Tzartos S, Tsetlin V, Granon S, Changeux JP, Komisarenko S, Cloëz-Tayarani I. Antibodies against extracellular domains of α4 and α7 subunits alter the levels of nicotinic receptors in the mouse brain and affect memory: possible relevance to Alzheimer's pathology. Journal of Alzheimer's Disease : Jad. 24: 693-704. PMID 21321393 DOI: 10.3233/JAD-2011-101842  1
2011 Nury H, Van Renterghem C, Weng Y, Tran A, Baaden M, Dufresne V, Changeux JP, Sonner JM, Delarue M, Corringer PJ. X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel. Nature. 469: 428-31. PMID 21248852 DOI: 10.1038/nature09647  1
2011 Changeux JP. The Neuroscience of Art: A Research Program for the Next Decade? Mind, Brain, and Education. 5: 3-4. DOI: 10.1111/j.1751-228X.2011.01102.x  1
2011 Markram H, Meier K, Lippert T, Grillner S, Frackowiak R, Dehaene S, Knoll A, Sompolinsky H, Verstreken K, DeFelipe J, Grant S, Changeux JP, Sariam A. Introducing the Human Brain Project Procedia Computer Science. 7: 39-42. DOI: 10.1016/j.procs.2011.12.015  1
2011 Dehaene S, Changeux JP, Naccache L. The global neuronal workspace model of conscious access: From neuronal architectures to clinical applications Research and Perspectives in Neurosciences. 18: 55-84. DOI: 10.1007/978-3-642-18015-6_4  1
2010 Cambon K, Dos-Santos Coura R, Groc L, Carbon A, Weissmann D, Changeux JP, Pujol JF, Granon S. Aggressive behavior during social interaction in mice is controlled by the modulation of tyrosine hydroxylase expression in the prefrontal cortex. Neuroscience. 171: 840-51. PMID 20923695 DOI: 10.1016/j.neuroscience.2010.09.015  1
2010 Villégier AS, Salomon L, Granon S, Champtiaux N, Changeux JP, Tassin JP. α7 and β2 nicotinic receptors control monoamine-mediated locomotor response. Neuroreport. 21: 1085-9. PMID 20890227 DOI: 10.1097/WNR.0b013e328340536a  1
2010 Azam L, Maskos U, Changeux JP, Dowell CD, Christensen S, De Biasi M, McIntosh JM. α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 5113-23. PMID 20739611 DOI: 10.1096/fj.10-166272  1
2010 Ballesteros-Yáñez I, Benavides-Piccione R, Bourgeois JP, Changeux JP, DeFelipe J. Alterations of cortical pyramidal neurons in mice lacking high-affinity nicotinic receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 11567-72. PMID 20534523 DOI: 10.1073/pnas.1006269107  1
2010 Lagercrantz H, Changeux JP. Basic consciousness of the newborn. Seminars in Perinatology. 34: 201-6. PMID 20494736 DOI: 10.1053/j.semperi.2010.02.004  1
2010 Changeux JP. Nicotine addiction and nicotinic receptors: lessons from genetically modified mice. Nature Reviews. Neuroscience. 11: 389-401. PMID 20485364 DOI: 10.1038/nrn2849  1
2010 Edelstein SJ, Changeux JP. Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors. Biophysical Journal. 98: 2045-52. PMID 20483311 DOI: 10.1016/j.bpj.2010.01.050  1
2010 Nury H, Poitevin F, Van Renterghem C, Changeux JP, Corringer PJ, Delarue M, Baaden M. One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proceedings of the National Academy of Sciences of the United States of America. 107: 6275-80. PMID 20308576 DOI: 10.1073/pnas.1001832107  1
2010 Vasbinder JW, Andersson B, Arthur WB, Boasson M, de Boer R, Changeux JP, Domingo E, Eigen M, Fersht A, Frenkel D, Rees M, Groen T, Huber R, Hunt T, Holland J, et al. Transdisciplinary EU science institute needs funds urgently. Nature. 463: 876. PMID 20164899 DOI: 10.1038/463876a  1
2010 Changeux JP. Allosteric receptors: from electric organ to cognition. Annual Review of Pharmacology and Toxicology. 50: 1-38. PMID 20055696 DOI: 10.1146/annurev.pharmtox.010909.105741  1
2010 Tolu S, Avale ME, Nakatani H, Pons S, Parnaudeau S, Tronche F, Vogt A, Monyer H, Vogel R, de Chaumont F, Olivo-Marin JC, Changeux JP, Maskos U. A versatile system for the neuronal subtype specific expression of lentiviral vectors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 723-30. PMID 19858094 DOI: 10.1096/fj.09-139790  1
2010 Lagercrantz H, Changeux JP. Consciousness: On the emergence of consciousness The Newborn Brain Neuroscience and Clinical Applications, Second Edition. 377-394. DOI: 10.1017/CBO9780511711848.025  1
2010 Changeux JP. Reflections on the origins of the human brain The Newborn Brain Neuroscience and Clinical Applications, Second Edition. 1-22. DOI: 10.1017/CBO9780511711848.003  1
2010 Changeux JP, Paas Y. Nicotinic Acetylcholine Receptors Encyclopedia of Neuroscience. 1129-1133. DOI: 10.1016/B978-008045046-9.01127-X  1
2009 Maouche K, Polette M, Jolly T, Medjber K, Cloëz-Tayarani I, Changeux JP, Burlet H, Terryn C, Coraux C, Zahm JM, Birembaut P, Tournier JM. {alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation. The American Journal of Pathology. 175: 1868-82. PMID 19808646 DOI: 10.2353/ajpath.2009.090212  1
2009 Wiklund A, Granon S, Faure P, Sundman E, Changeux JP, Eriksson LI. Object memory in young and aged mice after sevoflurane anaesthesia. Neuroreport. 20: 1419-23. PMID 19738500 DOI: 10.1097/WNR.0b013e328330cd2b  1
2009 Taly A, Corringer PJ, Guedin D, Lestage P, Changeux JP. Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nature Reviews. Drug Discovery. 8: 733-50. PMID 19721446 DOI: 10.1038/nrd2927  1
2009 Changeux JP. Jean-Pierre Changeux: allostery as neuro-enlightenment. Molecular Interventions. 9: 61-7. PMID 19401536 DOI: 10.1124/mi.9.2.2  1
2009 Changeux JP. Nicotinic receptors and nicotine addiction. Comptes Rendus Biologies. 332: 421-5. PMID 19393973 DOI: 10.1016/j.crvi.2009.02.005  1
2009 Grailhe R, Cardona A, Even N, Seif I, Changeux JP, Cloëz-Tayarani I. Regional changes in the cholinergic system in mice lacking monoamine oxidase A. Brain Research Bulletin. 78: 283-9. PMID 19111597 DOI: 10.1016/j.brainresbull.2008.12.004  1
2009 Lagercrantz H, Changeux JP. The emergence of human consciousness: from fetal to neonatal life. Pediatric Research. 65: 255-60. PMID 19092726 DOI: 10.1203/PDR.0b013e3181973b0d  1
2009 Bocquet N, Nury H, Baaden M, Le Poupon C, Changeux JP, Delarue M, Corringer PJ. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature. 457: 111-4. PMID 18987633 DOI: 10.1038/nature07462  1
2009 Suarez SV, Amadon A, Giacomini E, Wiklund A, Changeux JP, Le Bihan D, Granon S. Brain activation by short-term nicotine exposure in anesthetized wild-type and beta2-nicotinic receptors knockout mice: a BOLD fMRI study. Psychopharmacology. 202: 599-610. PMID 18818904 DOI: 10.1007/s00213-008-1338-x  1
2009 Changeux JP. Raison neurobiologique | Infléchir Ia trajectoire suiçidaire Quinzaine Litteraire. 5-6.  1
2009 Changeux JP. Forty years of enriching the museums of France through gifts | Quarante années d'enrichissement des musées de France par dation Revue Des Musees De France. 3-4.  1
2008 Maubourguet N, Lesne A, Changeux JP, Maskos U, Faure P. Behavioral sequence analysis reveals a novel role for beta2* nicotinic receptors in exploration. Plos Computational Biology. 4: e1000229. PMID 19023420 DOI: 10.1371/journal.pcbi.1000229  1
2008 Pons S, Fattore L, Cossu G, Tolu S, Porcu E, McIntosh JM, Changeux JP, Maskos U, Fratta W. Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12318-27. PMID 19020025 DOI: 10.1523/JNEUROSCI.3918-08.2008  1
2008 Wiklund A, Granon S, Cloëz-Tayarani I, Faure P, le Sourd AM, Sundman E, Changeux JP, Eriksson LI. Sevoflurane anesthesia alters exploratory and anxiety-like behavior in mice lacking the beta2 nicotinic acetylcholine receptor subunit. Anesthesiology. 109: 790-8. PMID 18946289 DOI: 10.1097/ALN.0b013e31818a379a  1
2008 Avale ME, Faure P, Pons S, Robledo P, Deltheil T, David DJ, Gardier AM, Maldonado R, Granon S, Changeux JP, Maskos U. Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion. Proceedings of the National Academy of Sciences of the United States of America. 105: 15991-6. PMID 18832468 DOI: 10.1073/pnas.0807635105  0.72
2008 Even N, Cardona A, Soudant M, Corringer PJ, Changeux JP, Cloëz-Tayarani I. Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors. Neuroreport. 19: 1545-50. PMID 18797314 DOI: 10.1097/WNR.0b013e3283112703  1
2008 Evrard A, Changeux JP. Abnormal response of dopaminergic neurons to nicotine without perturbation of nicotinic receptors in alphaCGRP knock-out mice. Brain Research. 1228: 89-96. PMID 18619948 DOI: 10.1016/j.brainres.2008.06.072  1
2008 Aráoz R, Herdman M, Rippka R, Ledreux A, Molgó J, Changeux JP, Tandeau de Marsac N, Nghiêm HO. A non-radioactive ligand-binding assay for detection of cyanobacterial anatoxins using Torpedo electrocyte membranes. Toxicon : Official Journal of the International Society On Toxinology. 52: 163-74. PMID 18617214 DOI: 10.1016/j.toxicon.2008.05.001  1
2008 Besson M, Suarez S, Cormier A, Changeux JP, Granon S. Chronic nicotine exposure has dissociable behavioural effects on control and beta2-/- mice. Behavior Genetics. 38: 503-14. PMID 18607712 DOI: 10.1007/s10519-008-9216-1  1
2008 Taly A, Changeux JP. Functional organization and conformational dynamics of the nicotinic receptor: a plausible structural interpretation of myasthenic mutations. Annals of the New York Academy of Sciences. 1132: 42-52. PMID 18567852 DOI: 10.1196/annals.1405.008  1
2008 Changeux JP, Taly A. Nicotinic receptors, allosteric proteins and medicine. Trends in Molecular Medicine. 14: 93-102. PMID 18262468 DOI: 10.1016/j.molmed.2008.01.001  1
2008 Jackson KJ, Martin BR, Changeux JP, Damaj MI. Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. The Journal of Pharmacology and Experimental Therapeutics. 325: 302-12. PMID 18184829 DOI: 10.1124/jpet.107.132977  1
2008 Putz G, Kristufek D, Orr-Urtreger A, Changeux JP, Huck S, Scholze P. Nicotinic acetylcholine receptor-subunit mRNAs in the mouse superior cervical ganglion are regulated by development but not by deletion of distinct subunit genes. Journal of Neuroscience Research. 86: 972-81. PMID 17975828 DOI: 10.1002/jnr.21559  1
2008 Changeux JP, Schmidt C. Foreword Revue D'Economie Politique. 118: 1-2.  1
2007 Kabbani N, Woll MP, Levenson R, Lindstrom JM, Changeux JP. Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics. Proceedings of the National Academy of Sciences of the United States of America. 104: 20570-5. PMID 18077321 DOI: 10.1073/pnas.0710314104  1
2007 Zanardi A, Ferrari R, Leo G, Maskos U, Changeux JP, Zoli M. Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 4028-37. PMID 17622669 DOI: 10.1096/fj.07-8260com  1
2007 Konstantakaki M, Changeux JP, Taly A. Docking of alpha-cobratoxin suggests a basal conformation of the nicotinic receptor. Biochemical and Biophysical Research Communications. 359: 413-8. PMID 17555709 DOI: 10.1016/j.bbrc.2007.05.126  1
2007 Besson M, Granon S, Mameli-Engvall M, Cloëz-Tayarani I, Maubourguet N, Cormier A, Cazala P, David V, Changeux JP, Faure P. Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proceedings of the National Academy of Sciences of the United States of America. 104: 8155-60. PMID 17470777 DOI: 10.1073/pnas.0702698104  1
2007 Moser N, Mechawar N, Jones I, Gochberg-Sarver A, Orr-Urtreger A, Plomann M, Salas R, Molles B, Marubio L, Roth U, Maskos U, Winzer-Serhan U, Bourgeois JP, Le Sourd AM, De Biasi M, ... ... Changeux JP, et al. Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures. Journal of Neurochemistry. 102: 479-92. PMID 17419810 DOI: 10.1111/j.1471-4159.2007.04498.x  1
2007 Scholze P, Orr-Urtreger A, Changeux JP, McIntosh JM, Huck S. Catecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulation. British Journal of Pharmacology. 151: 414-22. PMID 17401441 DOI: 10.1038/sj.bjp.0707236  1
2007 Skok MV, Grailhe R, Agenes F, Changeux JP. The role of nicotinic receptors in B-lymphocyte development and activation. Life Sciences. 80: 2334-6. PMID 17363009 DOI: 10.1016/j.lfs.2007.02.005  1
2007 Bocquet N, Prado de Carvalho L, Cartaud J, Neyton J, Le Poupon C, Taly A, Grutter T, Changeux JP, Corringer PJ. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature. 445: 116-9. PMID 17167423 DOI: 10.1038/nature05371  1
2007 Cloëz-Tayarani I, Changeux JP. Nicotine and serotonin in immune regulation and inflammatory processes: a perspective. Journal of Leukocyte Biology. 81: 599-606. PMID 17108054 DOI: 10.1189/jlb.0906544  1
2007 Changeux JP. The Molecular Biology of Consciousness† Consciousness Transitions. 123-160. DOI: 10.1016/B978-044452977-0/50007-3  1
2006 Molles BE, Maskos U, Pons S, Besson M, Guiard P, Guilloux JP, Evrard A, Cormier A, Mameli-Engvall M, Cloëz-Tayarani I, Nakatani H, Dufour N, Bemelmans AP, Mallet J, Cazala P, ... ... Changeux JP, et al. Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors. Journal of Molecular Neuroscience : Mn. 30: 105-6. PMID 17192649 DOI: 10.1385/JMN:30:1:105  1
2006 Grutter T, de Carvalho LP, Dufresne V, Taly A, Changeux JP. Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel. Journal of Molecular Neuroscience : Mn. 30: 63-4. PMID 17192629 DOI: 10.1385/JMN:30:1:63  1
2006 Taly A, Corringer PJ, Grutter T, Prado de Carvalho L, Karplus M, Changeux JP. Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proceedings of the National Academy of Sciences of the United States of America. 103: 16965-70. PMID 17077146 DOI: 10.1073/pnas.0607477103  1
2006 Changeux JP. The Ferrier Lecture 1998. The molecular biology of consciousness investigated with genetically modified mice. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 2239-59. PMID 17015398 DOI: 10.1098/rstb.2006.1832  1
2006 Vincent P, Maskos U, Charvet I, Bourgeais L, Stoppini L, Leresche N, Changeux JP, Lambert R, Meda P, Paupardin-Tritsch D. Live imaging of neural structure and function by fibred fluorescence microscopy. Embo Reports. 7: 1154-61. PMID 17008931 DOI: 10.1038/sj.embor.7400801  1
2006 Le Magueresse C, Safiulina V, Changeux JP, Cherubini E. Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice. The Journal of Physiology. 576: 533-46. PMID 16901939 DOI: 10.1113/jphysiol.2006.117572  1
2006 Zanetti L, de Kerchove D'Exaerde A, Zanardi A, Changeux JP, Picciotto MR, Zoli M. Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum. Psychopharmacology. 187: 181-8. PMID 16826402 DOI: 10.1007/s00213-006-0419-y  1
2006 Mameli-Engvall M, Evrard A, Pons S, Maskos U, Svensson TH, Changeux JP, Faure P. Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron. 50: 911-21. PMID 16772172 DOI: 10.1016/j.neuron.2006.05.007  1
2006 Granon S, Changeux JP. Attention-deficit/hyperactivity disorder: a plausible mouse model? Acta Paediatrica (Oslo, Norway : 1992). 95: 645-9. PMID 16754543 DOI: 10.1080/08035250600719747  1
2006 Besson M, David V, Suarez S, Cormier A, Cazala P, Changeux JP, Granon S. Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome. Psychopharmacology. 187: 189-99. PMID 16752141 DOI: 10.1007/s00213-006-0418-z  1
2006 Grailhe R, Merola F, Ridard J, Couvignou S, Le Poupon C, Changeux JP, Laguitton-Pasquier H. Monitoring protein interactions in the living cell through the fluorescence decays of the cyan fluorescent protein. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 7: 1442-54. PMID 16739159 DOI: 10.1002/cphc.200600057  1
2006 Dehaene S, Changeux JP, Naccache L, Sackur J, Sergent C. Conscious, preconscious, and subliminal processing: a testable taxonomy. Trends in Cognitive Sciences. 10: 204-11. PMID 16603406 DOI: 10.1016/j.tics.2006.03.007  1
2006 David V, Besson M, Changeux JP, Granon S, Cazala P. Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors. Neuropharmacology. 50: 1030-40. PMID 16580026 DOI: 10.1016/j.neuropharm.2006.02.003  1
2006 Sunesen M, de Carvalho LP, Dufresne V, Grailhe R, Savatier-Duclert N, Gibor G, Peretz A, Attali B, Changeux JP, Paas Y. Mechanism of Cl- selection by a glutamate-gated chloride (GluCl) receptor revealed through mutations in the selectivity filter. The Journal of Biological Chemistry. 281: 14875-81. PMID 16527818 DOI: 10.1074/jbc.M511657200  1
2006 Corringer PJ, Sallette J, Changeux JP. Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity? Journal of Physiology, Paris. 99: 162-71. PMID 16458492 DOI: 10.1016/j.jphysparis.2005.12.012  1
2006 Walters CL, Brown S, Changeux JP, Martin B, Damaj MI. The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology. 184: 339-44. PMID 16416156 DOI: 10.1007/s00213-005-0295-x  1
2006 Gutkin BS, Dehaene S, Changeux JP. A neurocomputational hypothesis for nicotine addiction. Proceedings of the National Academy of Sciences of the United States of America. 103: 1106-11. PMID 16415156 DOI: 10.1073/pnas.0510220103  1
2006 Villégier AS, Salomon L, Granon S, Changeux JP, Belluzzi JD, Leslie FM, Tassin JP. Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1704-13. PMID 16395299 DOI: 10.1038/sj.npp.1300987  1
2006 Skok M, Grailhe R, Agenes F, Changeux JP. The role of nicotinic acetylcholine receptors in lymphocyte development. Journal of Neuroimmunology. 171: 86-98. PMID 16253349 DOI: 10.1016/j.jneuroim.2005.09.011  1
2006 Changeux JP, Edelstein SJ. Allosteric receptors after 30 years Rendiconti Lincei. 17: 59-96. DOI: 10.1007/BF02904502  1
2006 West R, Markou A, Peto R, Perkins K, Shiffman S, Clarke PBS, Walton R, Bertrand D, Brody AL, Picciotto MR, Changeux JP, Balfour D, Heidbreder C. General discussion II Novartis Foundation Symposium. 275: 197-203.  1
2006 Changeux JP, Markou A, Shiffman S, West R, Stolerman I, Balfour D, Picciotto MR, Walton R, Clarke PBS, Corrigall WA, Bertrand D, Brody AL. Discussion Novartis Foundation Symposium. 275: 145-152.  1
2006 Maskos U, Granon S, Faure P, Changeux JP. Nicotinic acetylcholine receptor functions in the CNS investigated with a novel method of stereotaxic gene re-expression in knockout mice Novartis Foundation Symposium. 275: 64-79.  1
2006 Chiamulera C, Picciotto MR, Balfour D, Bertrand D, Clarke PBS, Corrigall WA, Caggiula A, Tyndale RF, Brody AL, Shiffman S, West R. Discussion Novartis Foundation Symposium. 275: 90-95.  0.84
2005 Grutter T, de Carvalho LP, Dufresne V, Taly A, Edelstein SJ, Changeux JP. Molecular tuning of fast gating in pentameric ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 102: 18207-12. PMID 16319224 DOI: 10.1073/pnas.0509024102  1
2005 Paas Y, Gibor G, Grailhe R, Savatier-Duclert N, Dufresne V, Sunesen M, de Carvalho LP, Changeux JP, Attali B. Pore conformations and gating mechanism of a Cys-loop receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 15877-82. PMID 16247006 DOI: 10.1073/pnas.0507599102  1
2005 Gotti C, Moretti M, Zanardi A, Gaimarri A, Champtiaux N, Changeux JP, Whiteaker P, Marks MJ, Clementi F, Zoli M. Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: identification of a new native nAChR subtype alpha3beta2(alpha5 or beta3) enriched in retinocollicular afferents. Molecular Pharmacology. 68: 1162-71. PMID 16049166 DOI: 10.1124/mol.105.015925  1
2005 Mrsic-Flogel TD, Hofer SB, Creutzfeldt C, Cloëz-Tayarani I, Changeux JP, Bonhoeffer T, Hübener M. Altered map of visual space in the superior colliculus of mice lacking early retinal waves. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6921-8. PMID 16033902 DOI: 10.1523/JNEUROSCI.1555-05.2005  1
2005 Maskos U, Molles BE, Pons S, Besson M, Guiard BP, Guilloux JP, Evrard A, Cazala P, Cormier A, Mameli-Engvall M, Dufour N, Cloëz-Tayarani I, Bemelmans AP, Mallet J, Gardier AM, ... ... Changeux JP, et al. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature. 436: 103-7. PMID 16001069 DOI: 10.1038/nature03694  1
2005 Skok M, Grailhe R, Changeux JP. Nicotinic receptors regulate B lymphocyte activation and immune response. European Journal of Pharmacology. 517: 246-51. PMID 15963492 DOI: 10.1016/j.ejphar.2005.05.011  1
2005 Sallette J, Pons S, Devillers-Thiery A, Soudant M, Prado de Carvalho L, Changeux JP, Corringer PJ. Nicotine upregulates its own receptors through enhanced intracellular maturation. Neuron. 46: 595-607. PMID 15944128 DOI: 10.1016/j.neuron.2005.03.029  1
2005 Changeux JP, Edelstein SJ. Allosteric mechanisms of signal transduction. Science (New York, N.Y.). 308: 1424-8. PMID 15933191 DOI: 10.1126/science.1108595  1
2005 Dehaene S, Changeux JP. Ongoing spontaneous activity controls access to consciousness: a neuronal model for inattentional blindness. Plos Biology. 3: e141. PMID 15819609 DOI: 10.1371/journal.pbio.0030141  1
2005 Grutter T, Prado de Carvalho L, Virginie D, Taly A, Fischer M, Changeux JP. A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels. Comptes Rendus Biologies. 328: 223-34. PMID 15810546 DOI: 10.1016/j.crvi.2004.11.004  1
2005 Taly A, Delarue M, Grutter T, Nilges M, Le Novère N, Corringer PJ, Changeux JP. Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophysical Journal. 88: 3954-65. PMID 15805177 DOI: 10.1529/biophysj.104.050229  1
2005 Cohen G, Roux JC, Grailhe R, Malcolm G, Changeux JP, Lagercrantz H. Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function. Proceedings of the National Academy of Sciences of the United States of America. 102: 3817-21. PMID 15738419 DOI: 10.1073/pnas.0409782102  1
2005 Gisiger T, Kerszberg M, Changeux JP. Acquisition and performance of delayed-response tasks: a neural network model. Cerebral Cortex (New York, N.Y. : 1991). 15: 489-506. PMID 15342439 DOI: 10.1093/cercor/bhh149  1
2005 Changeux JP. The visit of Professor Chen-Yuan Lee to the Pasteur Institute in 1970 and the use of a snake venom toxin to identify the acetylcholine receptor protein Journal of Toxicology - Toxin Reviews. 24: 15-41. DOI: 10.1081/TXR-200046237  1
2005 Skok MV, Grailhe R, Agenes F, Changeux JP. Signaling through nicotinic acetylcholine receptors regulates lymphocyte development and activation Ukrain'Skyi Biokhimichnyi Zhurnal. 77: 34.  1
2004 Strochlic L, Cartaud A, Mejat A, Grailhe R, Schaeffer L, Changeux JP, Cartaud J. 14-3-3 gamma associates with muscle specific kinase and regulates synaptic gene transcription at vertebrate neuromuscular synapse. Proceedings of the National Academy of Sciences of the United States of America. 101: 18189-94. PMID 15604144 DOI: 10.1073/pnas.0406905102  1
2004 Dauger S, Durand E, Cohen G, Lagercrantz H, Changeux JP, Gaultier C, Gallego J. Control of breathing in newborn mice lacking the beta-2 nAChR subunit. Acta Physiologica Scandinavica. 182: 205-12. PMID 15450117 DOI: 10.1111/j.1365-201X.2004.01345.x  1
2004 Pons S, Sallette J, Bourgeois JP, Taly A, Changeux JP, Devillers-Thiéry A. Critical role of the C-terminal segment in the maturation and export to the cell surface of the homopentameric alpha 7-5HT3A receptor. The European Journal of Neuroscience. 20: 2022-30. PMID 15450081 DOI: 10.1111/j.1460-9568.2004.03673.x  1
2004 Cormier A, Paas Y, Zini R, Tillement JP, Lagrue G, Changeux JP, Grailhe R. Long-term exposure to nicotine modulates the level and activity of acetylcholine receptors in white blood cells of smokers and model mice. Molecular Pharmacology. 66: 1712-8. PMID 15383622 DOI: 10.1124/mol.104.000463  1
2004 Maggi L, Sola E, Minneci F, Le Magueresse C, Changeux JP, Cherubini E. Persistent decrease in synaptic efficacy induced by nicotine at Schaffer collateral-CA1 synapses in the immature rat hippocampus. The Journal of Physiology. 559: 863-74. PMID 15272042 DOI: 10.1113/jphysiol.2004.067041  1
2004 Schütz B, Mauer D, Salmon AM, Changeux JP, Zimmer A. Analysis of the cellular expression pattern of beta-CGRP in alpha-CGRP-deficient mice. The Journal of Comparative Neurology. 476: 32-43. PMID 15236465 DOI: 10.1002/cne.20211  1
2004 Léna C, Popa D, Grailhe R, Escourrou P, Changeux JP, Adrien J. Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5711-8. PMID 15215293 DOI: 10.1523/JNEUROSCI.3882-03.2004  1
2004 Mechawar N, Saghatelyan A, Grailhe R, Scoriels L, Gheusi G, Gabellec MM, Lledo PM, Changeux JP. Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proceedings of the National Academy of Sciences of the United States of America. 101: 9822-6. PMID 15210938 DOI: 10.1073/pnas.0403361101  1
2004 Cordero-Erausquin M, Pons S, Faure P, Changeux JP. Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord. Pain. 109: 308-18. PMID 15157692 DOI: 10.1016/j.pain.2004.01.034  1
2004 Salmon AM, Evrard A, Damaj I, Changeux JP. Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice. Neuroscience Letters. 360: 73-6. PMID 15082182 DOI: 10.1016/j.neulet.2004.02.031  1
2004 Grailhe R, de Carvalho LP, Paas Y, Le Poupon C, Soudant M, Bregestovski P, Changeux JP, Corringer PJ. Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons. The European Journal of Neuroscience. 19: 855-62. PMID 15009132 DOI: 10.1111/j.1460-9568.2004.03153.x  1
2004 Grutter T, Le Novère N, Changeux JP. Rational understanding of nicotinic receptors drug binding. Current Topics in Medicinal Chemistry. 4: 645-50. PMID 14965300 DOI: 10.2174/1568026043451177  1
2004 Sallette J, Bohler S, Benoit P, Soudant M, Pons S, Le Novère N, Changeux JP, Corringer PJ. An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. The Journal of Biological Chemistry. 279: 18767-75. PMID 14764595 DOI: 10.1074/jbc.M308260200  1
2004 Champtiaux N, Changeux JP. Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system. Progress in Brain Research. 145: 235-51. PMID 14650919  1
2003 Grubb MS, Rossi FM, Changeux JP, Thompson ID. Abnormal functional organization in the dorsal lateral geniculate nucleus of mice lacking the beta 2 subunit of the nicotinic acetylcholine receptor. Neuron. 40: 1161-72. PMID 14687550 DOI: 10.1016/S0896-6273(03)00789-X  1
2003 Sunesen M, Huchet-Dymanus M, Christensen MO, Changeux JP. Phosphorylation-elicited quaternary changes of GA binding protein in transcriptional activation. Molecular and Cellular Biology. 23: 8008-18. PMID 14585962 DOI: 10.1128/MCB.23.22.8008-8018.2003  1
2003 Devillers-Thiéry A, Bourgeois JP, Pons S, Le Sourd A, Pucci B, Changeux JP. An in vitro study of the sub-cellular distribution of nicotinic receptors. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 95: 373-81. PMID 14519554 DOI: 10.1016/S0248-4900(03)00084-4  1
2003 Skok MV, Kalashnik EN, Koval LN, Tsetlin VI, Utkin YN, Changeux JP, Grailhe R. Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines. Molecular Pharmacology. 64: 885-9. PMID 14500745 DOI: 10.1124/mol.64.4.885  1
2003 Paas Y, Cartaud J, Recouvreur M, Grailhe R, Dufresne V, Pebay-Peyroula E, Landau EM, Changeux JP. Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices. Proceedings of the National Academy of Sciences of the United States of America. 100: 11309-14. PMID 13679581 DOI: 10.1073/pnas.1834451100  1
2003 Champtiaux N, Gotti C, Cordero-Erausquin M, David DJ, Przybylski C, Léna C, Clementi F, Moretti M, Rossi FM, Le Novère N, McIntosh JM, Gardier AM, Changeux JP. Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7820-9. PMID 12944511  0.96
2003 Granon S, Faure P, Changeux JP. Executive and social behaviors under nicotinic receptor regulation. Proceedings of the National Academy of Sciences of the United States of America. 100: 9596-601. PMID 12876201 DOI: 10.1073/pnas.1533498100  1
2003 Dehaene S, Sergent C, Changeux JP. A neuronal network model linking subjective reports and objective physiological data during conscious perception. Proceedings of the National Academy of Sciences of the United States of America. 100: 8520-5. PMID 12829797 DOI: 10.1073/pnas.1332574100  1
2003 Grutter T, Prado de Carvalho L, Le Novère N, Corringer PJ, Edelstein S, Changeux JP. An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. The Embo Journal. 22: 1990-2003. PMID 12727867 DOI: 10.1093/emboj/cdg197  1
2003 Han ZY, Zoli M, Cardona A, Bourgeois JP, Changeux JP, Le Novère N. Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]alpha-bungarotoxin binding sites in the brain of Macaca mulatta. The Journal of Comparative Neurology. 461: 49-60. PMID 12722104 DOI: 10.1002/cne.10659  1
2003 Marubio LM, Gardier AM, Durier S, David D, Klink R, Arroyo-Jimenez MM, McIntosh JM, Rossi F, Champtiaux N, Zoli M, Changeux JP. Effects of nicotine in the dopaminergic system of mice lacking the alpha4 subunit of neuronal nicotinic acetylcholine receptors. The European Journal of Neuroscience. 17: 1329-37. PMID 12713636 DOI: 10.1046/j.1460-9568.2003.02564.x  1
2003 Maggi L, Le Magueresse C, Changeux JP, Cherubini E. Nicotine activates immature "silent" connections in the developing hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 100: 2059-64. PMID 12582205 DOI: 10.1073/pnas.0437947100  1
2003 Changeux JP. Molecular mechanisms of nicotine dependence | Mécanismes moléculaires de la dépendance à la nicotine Biofutur. 22-25.  1
2002 Champtiaux N, Changeux JP. Knock-out and knock-in mice to investigate the role of nicotinic receptors in the central nervous system. Current Drug Targets. Cns and Neurological Disorders. 1: 319-30. PMID 12769606  1
2002 Le Novère N, Corringer PJ, Changeux JP. The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. Journal of Neurobiology. 53: 447-56. PMID 12436412 DOI: 10.1002/neu.10153  1
2002 de Kerchove D'Exaerde A, Cartaud J, Ravel-Chapuis A, Seroz T, Pasteau F, Angus LM, Jasmin BJ, Changeux JP, Schaeffer L. Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene expression. Embo Reports. 3: 1075-81. PMID 12393756 DOI: 10.1093/embo-reports/kvf220  1
2002 Marchand S, Devillers-Thiéry A, Pons S, Changeux JP, Cartaud J. Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8891-901. PMID 12388596  1
2002 Martinez KL, Gohon Y, Corringer PJ, Tribet C, Mérola F, Changeux JP, Popot JL. Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints. Febs Letters. 528: 251-6. PMID 12297315 DOI: 10.1016/S0014-5793(02)03306-9  1
2002 Cohen G, Han ZY, Grailhe R, Gallego J, Gaultier C, Changeux JP, Lagercrantz H. beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. Proceedings of the National Academy of Sciences of the United States of America. 99: 13272-7. PMID 12228730 DOI: 10.1073/pnas.192463599  1
2002 Ferrari R, Le Novère N, Picciotto MR, Changeux JP, Zoli M. Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections. The European Journal of Neuroscience. 15: 1810-8. PMID 12081661 DOI: 10.1046/j.1460-9568.2001.02009.x  1
2002 Shoaib M, Gommans J, Morley A, Stolerman IP, Grailhe R, Changeux JP. The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion. Neuropharmacology. 42: 530-9. PMID 11955523 DOI: 10.1016/S0028-3908(01)00194-0  1
2002 Fruchart-Gaillard C, Gilquin B, Antil-Delbeke S, Le Novère N, Tamiya T, Corringer PJ, Changeux JP, Ménez A, Servent D. Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 99: 3216-21. PMID 11867717 DOI: 10.1073/pnas.042699899  1
2002 Le Novère N, Grutter T, Changeux JP. Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites. Proceedings of the National Academy of Sciences of the United States of America. 99: 3210-5. PMID 11867716 DOI: 10.1073/pnas.042699699  1
2002 Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A. Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. European Journal of Biochemistry / Febs. 269: 519-26. PMID 11856310 DOI: 10.1046/j.0014-2956.2001.02674.x  1
2002 Champtiaux N, Han ZY, Bessis A, Rossi FM, Zoli M, Marubio L, McIntosh JM, Changeux JP. Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1208-17. PMID 11850448  1
2002 Laudenbach V, Medja F, Zoli M, Rossi FM, Evrard P, Changeux JP, Gressens P. Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 423-5. PMID 11790724 DOI: 10.1096/fj.01-0532fje  1
2001 Le Novère N, Changeux JP. The Ligand Gated Ion Channel database: an example of a sequence database in neuroscience. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 1121-30. PMID 11545694 DOI: 10.1098/rstb.2001.0903  1
2001 Grutter T, Changeux JP. Nicotinic receptors in wonderland. Trends in Biochemical Sciences. 26: 459-63. PMID 11504610 DOI: 10.1016/S0968-0004(01)01921-1  1
2001 Schaeffer L, de Kerchove d'Exaerde A, Changeux JP. Targeting transcription to the neuromuscular synapse. Neuron. 31: 15-22. PMID 11498047 DOI: 10.1016/S0896-6273(01)00353-1  1
2001 Lukas RJ, Lucero L, Buisson B, Galzi JL, Puchacz E, Fryer JD, Changeux JP, Bertrand D. Neurotoxicity of channel mutations in heterologously expressed alpha7-nicotinic acetylcholine receptors. The European Journal of Neuroscience. 13: 1849-60. PMID 11403678 DOI: 10.1046/j.0953-816X.2001.01560.x  1
2001 Changeux JP, Edelstein SJ. Allosteric mechanisms in normal and pathological nicotinic acetylcholine receptors Current Opinion in Neurobiology. 11: 369-377. PMID 11399437 DOI: 10.1016/S0959-4388(00)00221-X  1
2001 Changeux JP. Cajal on neurons, molecules, and consciousness. Annals of the New York Academy of Sciences. 929: 147-51. PMID 11349423  1
2001 Rossi FM, Pizzorusso T, Porciatti V, Marubio LM, Maffei L, Changeux JP. Requirement of the nicotinic acetylcholine receptor beta 2 subunit for the anatomical and functional development of the visual system. Proceedings of the National Academy of Sciences of the United States of America. 98: 6453-8. PMID 11344259 DOI: 10.1073/pnas.101120998  1
2001 Bohler S, Gay S, Bertrand S, Corringer PJ, Edelstein SJ, Changeux JP, Bertrand D. Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit. Biochemistry. 40: 2066-74. PMID 11329274 DOI: 10.1021/bi0020022  1
2001 Zachariou V, Caldarone BJ, Weathers-Lowin A, George TP, Elsworth JD, Roth RH, Changeux JP, Picciotto MR. Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 576-89. PMID 11282258 DOI: 10.1016/S0893-133X(00)00224-4  1
2001 Salmon AM, Damaj MI, Marubio LM, Epping-Jordan MP, Merlo-Pich E, Changeux JP. Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice. Nature Neuroscience. 4: 357-8. PMID 11276224 DOI: 10.1038/86001  1
2001 Fischer M, Corringer PJ, Schott K, Bacher A, Changeux JP. A method for soluble overexpression of the alpha7 nicotinic acetylcholine receptor extracellular domain. Proceedings of the National Academy of Sciences of the United States of America. 98: 3567-70. PMID 11248118 DOI: 10.1073/pnas.041594798  1
2001 Cordero-Erausquin M, Changeux JP. Tonic nicotinic modulation of serotoninergic transmission in the spinal cord. Proceedings of the National Academy of Sciences of the United States of America. 98: 2803-7. PMID 11226321 DOI: 10.1073/pnas.041600698  1
2001 Klink R, de Kerchove d'Exaerde A, Zoli M, Changeux JP. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1452-63. PMID 11222635  1
2001 Altiok N, Changeux JP. Electrical activity regulates AChR gene expression via JNK, PKCzeta and Sp1 in skeletal chick muscle. Febs Letters. 487: 333-8. PMID 11163354 DOI: 10.1016/S0014-5793(00)02311-5  1
2001 Grady SR, Meinerz NM, Cao J, Reynolds AM, Picciotto MR, Changeux JP, McIntosh JM, Marks MJ, Collins AC. Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum. Journal of Neurochemistry. 76: 258-68. PMID 11145999 DOI: 10.1046/j.1471-4159.2001.00019.x  1
2001 Le Novère N, Changeux JP. LGICdb: the ligand-gated ion channel database. Nucleic Acids Research. 29: 294-5. PMID 11125117  1
2000 Dehaene S, Changeux JP. Reward-dependent learning in neuronal networks for planning and decision making. Progress in Brain Research. 126: 217-29. PMID 11105649 DOI: 10.1016/S0079-6123(00)26016-0  1
2000 Marks MJ, Stitzel JA, Grady SR, Picciotto MR, Changeux JP, Collins AC. Nicotinic-agonist stimulated (86)Rb(+) efflux and [(3)H]epibatidine binding of mice differing in beta2 genotype. Neuropharmacology. 39: 2632-45. PMID 11044733 DOI: 10.1016/S0028-3908(00)00115-5  1
2000 Han ZY, Le Novère N, Zoli M, Hill JA, Champtiaux N, Changeux JP. Localization of nAChR subunit mRNAs in the brain of Macaca mulatta. The European Journal of Neuroscience. 12: 3664-74. PMID 11029636 DOI: 10.1046/j.1460-9568.2000.00262.x  1
2000 Tsuneki H, Klink R, Léna C, Korn H, Changeux JP. Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta. The European Journal of Neuroscience. 12: 2475-85. PMID 10947823 DOI: 10.1046/j.1460-9568.2000.00138.x  1
2000 Rogner UC, Spyropoulos DD, Le Novère N, Changeux JP, Avner P. Control of neurulation by the nucleosome assembly protein-1-like 2. Nature Genetics. 25: 431-5. PMID 10932189 DOI: 10.1038/78124  1
2000 Antil-Delbeke S, Gaillard C, Tamiya T, Corringer PJ, Changeux JP, Servent D, Ménez A. Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 275: 29594-601. PMID 10852927 DOI: 10.1074/jbc.M909746199  1
2000 Martinez KL, Corringer PJ, Edelstein SJ, Changeux JP, Mérola F. Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time-resolved fluorescence spectroscopy. Biochemistry. 39: 6979-90. PMID 10841780 DOI: 10.1021/bi992811p  1
2000 Cordero-Erausquin M, Marubio LM, Klink R, Changeux JP. Nicotinic receptor function: new perspectives from knockout mice. Trends in Pharmacological Sciences. 21: 211-7. PMID 10838608  0.6
2000 Corringer PJ, Le Novère N, Changeux JP. Nicotinic receptors at the amino acid level. Annual Review of Pharmacology and Toxicology. 40: 431-58. PMID 10836143 DOI: 10.1146/annurev.pharmtox.40.1.431  0.76
2000 Servent D, Antil-Delbeke S, Gaillard C, Corringer PJ, Changeux JP, Ménez A. Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors. European Journal of Pharmacology. 393: 197-204. PMID 10771013  0.76
2000 Whiteaker P, Marks MJ, Grady SR, Lu Y, Picciotto MR, Changeux JP, Collins AC. Pharmacological and null mutation approaches reveal nicotinic receptor diversity. European Journal of Pharmacology. 393: 123-35. PMID 10771005 DOI: 10.1016/S0014-2999(00)00052-2  1
2000 Marubio LM, Changeux JP. Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function European Journal of Pharmacology. 393: 113-121. PMID 10771004 DOI: 10.1016/S0014-2999(00)00007-8  1
2000 Gisiger T, Dehaene S, Changeux JP. Computational models of association cortex. Current Opinion in Neurobiology. 10: 250-9. PMID 10753797 DOI: 10.1016/S0959-4388(00)00075-1  1
2000 Paas Y, Devillers-Thiéry A, Teichberg VI, Changeux JP, Eisenstein M. How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors. Trends in Pharmacological Sciences. 21: 87-92. PMID 10689361 DOI: 10.1016/S0165-6147(99)01443-1  1
2000 Paas-Rozner M, Dayan M, Paas Y, Changeux JP, Wirguin I, Sela M, Mozes E. Oral administration of a dual analog of two myasthenogenic T cell epitopes down-regulates experimental autoimmune myasthenia gravis in mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 2168-73. PMID 10681457 DOI: 10.1073/pnas.040554597  1
2000 Changeux JP, Dehaene S. Hierarchical neuronal modeling of cognitive functions: from synaptic transmission to the Tower of London. International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology. 35: 179-87. PMID 10677646 DOI: 10.1016/S0167-8760(99)00052-5  1
2000 Changeux JP. An allosteric orchestra Medecine/Sciences. 16: 591-592.  1
2000 Changeux JP. Nicotinic receptors: From molecular biology to psychiatric diseases American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 453.  1
1999 Picciotto MR, Zoli M, Changeux JP. Use of knock-out mice to determine the molecular basis for the actions of nicotine. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 1: S121-5; discussion S. PMID 11768168  1
1999 Epping-Jordan MP, Picciotto MR, Changeux JP, Pich EM. Assessment of nicotinic acetylcholine receptor subunit contributions to nicotine self-administration in mutant mice. Psychopharmacology. 147: 25-6. PMID 10591862 DOI: 10.1007/s002130051135  1
1999 le Novère N, Zoli M, Léna C, Ferrari R, Picciotto MR, Merlo-Pich E, Changeux JP. Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion. Neuroreport. 10: 2497-501. PMID 10574359  0.84
1999 Léna C, de Kerchove D'Exaerde A, Cordero-Erausquin M, Le Novère N, del Mar Arroyo-Jimenez M, Changeux JP. Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons. Proceedings of the National Academy of Sciences of the United States of America. 96: 12126-31. PMID 10518587 DOI: 10.1073/pnas.96.21.12126  1
1999 Bertrand D, Changeux JP. Nicotinic receptor: a prototype of allosteric ligand-gated ion channels and its possible implications in epilepsy. Advances in Neurology. 79: 171-88. PMID 10514813  1
1999 Corringer PJ, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Molecular basis of the charge selectivity of nicotinic acetylcholine receptor and related ligand-gated ion channels. Novartis Foundation Symposium. 225: 215-24; discussion 2. PMID 10472058  1
1999 Arroyo-Jim nez MM, Bourgeois JP, Marubio LM, Le Sourd AM, Ottersen OP, Rinvik E, Fairén A, Changeux JP. Ultrastructural localization of the alpha4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6475-87. PMID 10414976  1
1999 Léna C, Changeux JP. The role of beta 2-subunit-containing nicotinic acetylcholine receptors in the brain explored with a mutant mouse. Annals of the New York Academy of Sciences. 868: 611-6. PMID 10414341 DOI: 10.1111/j.1749-6632.1999.tb11333.x  1
1999 Lukas RJ, Changeux JP, Le Novère N, Albuquerque EX, Balfour DJ, Berg DK, Bertrand D, Chiappinelli VA, Clarke PB, Collins AC, Dani JA, Grady SR, Kellar KJ, Lindstrom JM, Marks MJ, et al. International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits. Pharmacological Reviews. 51: 397-401. PMID 10353988  1
1999 Marubio LM, del Mar Arroyo-Jimenez M, Cordero-Erausquin M, Léna C, Le Novère N, de Kerchove d'Exaerde A, Huchet M, Damaj MI, Changeux JP. Reduced antinociception in mice lacking neuronal nicotinic receptor subunits. Nature. 398: 805-10. PMID 10235262 DOI: 10.1038/19756  1
1999 Le Novère N, Corringer PJ, Changeux JP. Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation. Biophysical Journal. 76: 2329-45. PMID 10233052 DOI: 10.1016/S0006-3495(99)77390-X  1
1999 Corringer PJ, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor. Neuron. 22: 831-43. PMID 10230802 DOI: 10.1016/S0896-6273(00)80741-2  1
1999 Marks MJ, Whiteaker P, Calcaterra J, Stitzel JA, Bullock AE, Grady SR, Picciotto MR, Changeux JP, Collins AC. Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit. The Journal of Pharmacology and Experimental Therapeutics. 289: 1090-103. PMID 10215692  1
1999 Salmon AM, Damaj I, Sekine S, Picciotto MR, Marubio L, Changeux JP. Modulation of morphine analgesia in alphaCGRP mutant mice. Neuroreport. 10: 849-54. PMID 10208559  1
1999 Gramolini AO, Angus LM, Schaeffer L, Burton EA, Tinsley JM, Davies KE, Changeux JP, Jasmin BJ. Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 3223-7. PMID 10077665 DOI: 10.1073/pnas.96.6.3223  1
1999 Zoli M, Picciotto MR, Ferrari R, Cocchi D, Changeux JP. Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. The Embo Journal. 18: 1235-44. PMID 10064590 DOI: 10.1093/emboj/18.5.1235  1
1999 Le Novère N, Changeux JP. The Ligand Gated Ion Channel Database. Nucleic Acids Research. 27: 340-2. PMID 9847222 DOI: 10.1093/nar/27.1.340  1
1998 Changeux JP. [Reflections of a neurobiologist on the origin of ethics]. Comptes Rendus Des SéAnces De La SociéTé De Biologie Et De Ses Filiales. 192: 1041-9. PMID 10101601  1
1998 Changeux JP, Edelstein SJ. Allosteric receptors after 30 years. Neuron. 21: 959-80. PMID 9856454 DOI: 10.1016/S0896-6273(00)80616-9  1
1998 Dehaene S, Kerszberg M, Changeux JP. A neuronal model of a global workspace in effortful cognitive tasks. Proceedings of the National Academy of Sciences of the United States of America. 95: 14529-34. PMID 9826734 DOI: 10.1073/pnas.95.24.14529  1
1998 Kerszberg M, Changeux JP. A simple molecular model of neurulation. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 758-70. PMID 9819565 DOI: 10.1002/(SICI)1521-1878(199809)20:9<758::AID-BIES9>3.0.CO;2-C  1
1998 Lu Y, Grady S, Marks MJ, Picciotto M, Changeux JP, Collins AC. Pharmacological characterization of nicotinic receptor-stimulated GABA release from mouse brain synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 287: 648-57. PMID 9808692  1
1998 Servent D, Thanh HL, Antil S, Bertrand D, Corringer PJ, Changeux JP, Ménez A. Functional determinants by which snake and cone snail toxins block the alpha 7 neuronal nicotinic acetylcholine receptors. Journal of Physiology, Paris. 92: 107-11. PMID 9782452  0.76
1998 Léna C, Changeux JP. Allosteric nicotinic receptors, human pathologies. Journal of Physiology, Paris. 92: 63-74. PMID 9782446 DOI: 10.1016/S0928-4257(98)80140-X  1
1998 Changeux JP, Dehaene S. Hierarchical neuronal modeling of cognitive functions: from synaptic transmission to the Tower of London. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 321: 241-7. PMID 9759348 DOI: 10.1016/S0764-4469(97)89829-0  1
1998 Watanabe H, Zoli M, Changeux JP. Promoter analysis of the neuronal nicotinic acetylcholine receptor alpha4 gene: methylation and expression of the transgene. The European Journal of Neuroscience. 10: 2244-53. PMID 9749753  0.6
1998 Changeux JP, Bertrand D, Corringer PJ, Dehaene S, Edelstein S, Léna C, Le Novère N, Marubio L, Picciotto M, Zoli M. Brain nicotinic receptors: structure and regulation, role in learning and reinforcement. Brain Research. Brain Research Reviews. 26: 198-216. PMID 9651527 DOI: 10.1016/S0165-0173(97)00040-4  1
1998 Salmon AM, Bruand C, Cardona A, Changeux JP, Berrih-Aknin S. An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis. The Journal of Clinical Investigation. 101: 2340-50. PMID 9616205 DOI: 10.1172/JCI1615  0.44
1998 Edelstein SJ, Changeux JP. Allosteric transitions of the acetylcholine receptor. Advances in Protein Chemistry. 51: 121-84. PMID 9615170  1
1998 Zoli M, Léna C, Picciotto MR, Changeux JP. Identification of four classes of brain nicotinic receptors using beta2 mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4461-72. PMID 9614223  1
1998 Bessereau JL, Laudenbach V, Le Poupon C, Changeux JP. Nonmyogenic factors bind nicotinic acetylcholine receptor promoter elements required for response to denervation. The Journal of Biological Chemistry. 273: 12786-93. PMID 9582305  0.36
1998 Krause RM, Buisson B, Bertrand S, Corringer PJ, Galzi JL, Changeux JP, Bertrand D. Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor. Molecular Pharmacology. 53: 283-94. PMID 9463487  1
1998 Picciotto MR, Zoli M, Rimondini R, Léna C, Marubio LM, Pich EM, Fuxe K, Changeux JP. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature. 391: 173-7. PMID 9428762 DOI: 10.1038/34413  1
1998 Corringer PJ, Bertrand S, Bohler S, Edelstein SJ, Changeux JP, Bertrand D. Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 648-57. PMID 9425007  1
1998 Changeux JP. Drug use and abuse Daedalus. 127: 145-165.  1
1997 Edelstein SJ, Schaad O, Changeux JP. Myasthenic nicotinic receptor mutant interpreted in terms of the allosteric model. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 320: 953-61. PMID 9587473 DOI: 10.1016/S0764-4469(97)82468-7  1
1997 Bertrand S, Devillers-Thiéry A, Palma E, Buisson B, Edelstein SJ, Corringer PJ, Changeux JP, Bertrand D. Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants. Neuroreport. 8: 3591-6. PMID 9427332  1
1997 Picciotto MR, Zoli M, Zachariou V, Changeux JP. Contribution of nicotinic acetylcholine receptors containing the beta 2-subunit to the behavioural effects of nicotine. Biochemical Society Transactions. 25: 824-9. PMID 9388554  1
1997 Léna C, Changeux JP. Pathological mutations of nicotinic receptors and nicotine-based therapies for brain disorders. Current Opinion in Neurobiology. 7: 674-82. PMID 9384554 DOI: 10.1016/S0959-4388(97)80088-8  1
1997 Beeri R, Le Novère N, Mervis R, Huberman T, Grauer E, Changeux JP, Soreq H. Enhanced hemicholinium binding and attenuated dendrite branching in cognitively impaired acetylcholinesterase-transgenic mice. Journal of Neurochemistry. 69: 2441-51. PMID 9375677  1
1997 Edelstein SJ, Schaad O, Changeux JP. Single binding versus single channel recordings: a new approach to study ionotropic receptors. Biochemistry. 36: 13755-60. PMID 9374851 DOI: 10.1021/bi9718301  1
1997 Dehaene S, Changeux JP. A hierarchical neuronal network for planning behavior. Proceedings of the National Academy of Sciences of the United States of America. 94: 13293-8. PMID 9371839 DOI: 10.1073/pnas.94.24.13293  1
1997 Bessis A, Champtiaux N, Chatelin L, Changeux JP. The neuron-restrictive silencer element: a dual enhancer/silencer crucial for patterned expression of a nicotinic receptor gene in the brain. Proceedings of the National Academy of Sciences of the United States of America. 94: 5906-11. PMID 9159173  0.52
1997 Léna C, Changeux JP. Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 576-85. PMID 8987780  1
1996 Changeux JP. Molecular mechanisms of synaptic transmission and its regulation: application to models of cognitive functions. Neuroimage. 4: S7-11. PMID 9345516 DOI: 10.1006/nimg.1996.0041  1
1996 Changeux JP, Bessis A, Bourgeois JP, Corringer PJ, Devillers-Thiery A, Eiselé JL, Kerszberg M, Léna C, Le Novère N, Picciotto M, Zoli M. Nicotinic receptors and brain plasticity. Cold Spring Harbor Symposia On Quantitative Biology. 61: 343-62. PMID 9246464  1
1996 Edelstein SJ, Changeux JP. Allosteric proteins after thirty years: the binding and state functions of the neuronal alpha 7 nicotinic acetylcholine receptors. Experientia. 52: 1083-90. PMID 8988250 DOI: 10.1007/BF01952106  1
1996 Edelstein SJ, Schaad O, Henry E, Bertrand D, Changeux JP. A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions. Biological Cybernetics. 75: 361-79. PMID 8983160  1
1996 Le Novère N, Zoli M, Changeux JP. Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain. The European Journal of Neuroscience. 8: 2428-39. PMID 8950106  0.6
1996 Galzi JL, Bertrand S, Corringer PJ, Changeux JP, Bertrand D. Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor. The Embo Journal. 15: 5824-32. PMID 8918460  1
1996 Yu D, Zhang L, Eiselé JL, Bertrand D, Changeux JP, Weight FF. Ethanol inhibition of nicotinic acetylcholine type alpha 7 receptors involves the amino-terminal domain of the receptor. Molecular Pharmacology. 50: 1010-6. PMID 8863848  1
1996 Milton NG, Bessis A, Changeux JP, Latchman DS. Differential regulation of neuronal nicotinic acetylcholine receptor subunit gene promoters by Brn-3 POU family transcription factors. The Biochemical Journal. 317: 419-23. PMID 8713067  0.52
1996 Paas Y, Devillers-Thiéry A, Changeux JP, Medevielle F, Teichberg VI. Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor. The Embo Journal. 15: 1548-56. PMID 8612578  1
1996 Vidal C, Changeux JP. Neuronal nicotinic acetylcholine receptors in the brain News in Physiological Sciences. 11: 202-214.  1
1995 Bessis A, Salmon AM, Zoli M, Le Novère N, Picciotto M, Changeux JP. Promoter elements conferring neuron-specific expression of the beta 2-subunit of the neuronal nicotinic acetylcholine receptor studied in vitro and in transgenic mice. Neuroscience. 69: 807-19. PMID 8596650 DOI: 10.1016/0306-4522(95)00303-Z  1
1995 Dehaene S, Changeux JP. Neuronal models of prefrontal cortical functions. Annals of the New York Academy of Sciences. 769: 305-19. PMID 8595034 DOI: 10.1111/j.1749-6632.1995.tb38147.x  1
1995 Zoli M, Le Novère N, Hill JA, Changeux JP. Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1912-39. PMID 7891142  0.6
1995 Picciotto MR, Zoli M, Léna C, Bessis A, Lallemand Y, Le Novère N, Vincent P, Pich EM, Brûlet P, Changeux JP. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature. 374: 65-7. PMID 7870173 DOI: 10.1038/374065a0  1
1995 Milton NG, Bessis A, Changeux JP, Latchman DS. The neuronal nicotinic acetylcholine receptor alpha 2 subunit gene promoter is activated by the Brn-3b POU family transcription factor and not by Brn-3a or Brn-3c. The Journal of Biological Chemistry. 270: 15143-7. PMID 7797498  0.52
1995 Jasmin BJ, Antony C, Changeux JP, Cartaud J. Nerve-dependent plasticity of the Golgi complex in skeletal muscle fibres: compartmentalization within the subneural sarcoplasm. The European Journal of Neuroscience. 7: 470-9. PMID 7773444 DOI: 10.1111/j.1460-9568.1995.tb00343.x  1
1995 Corringer PJ, Galzi JL, Eiselé JL, Bertrand S, Changeux JP, Bertrand D. Identification of a new component of the agonist binding site of the nicotinic alpha 7 homooligomeric receptor. The Journal of Biological Chemistry. 270: 11749-52. PMID 7744821 DOI: 10.1074/jbc.270.20.11749  0.6
1995 Cartaud A, Jasmin BJ, Changeux JP, Cartaud J. Direct involvement of a lamin-B-related (54 kDa) protein in the association of intermediate filaments with the postsynaptic membrane of the Torpedo marmorata electrocyte. Journal of Cell Science. 108: 153-60. PMID 7738092  1
1995 Duclert A, Changeux JP. Acetylcholine receptor gene expression at the developing neuromuscular junction. Physiological Reviews. 75: 339-68. PMID 7724666  1
1995 Granon S, Poucet B, Thinus-Blanc C, Changeux JP, Vidal C. Nicotinic and muscarinic receptors in the rat prefrontal cortex: differential roles in working memory, response selection and effortful processing. Psychopharmacology. 119: 139-44. PMID 7659760 DOI: 10.1007/BF02246154  1
1995 Li XM, Zoli M, Finnman UB, Le Novère N, Changeux JP, Fuxe K. A single (-)-nicotine injection causes change with a time delay in the affinity of striatal D2 receptors for antagonist, but not for agonist, nor in the D2 receptor mRNA levels in the rat substantia nigra. Brain Research. 679: 157-67. PMID 7648259  0.6
1995 Antony C, Huchet M, Changeux JP, Cartaud J. Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle. The Journal of Cell Biology. 130: 959-68. PMID 7642711  0.64
1995 Legay C, Huchet M, Massoulié J, Changeux JP. Developmental regulation of acetylcholinesterase transcripts in the mouse diaphragm: alternative splicing and focalization. The European Journal of Neuroscience. 7: 1803-9. PMID 7582132  0.64
1995 Galzi JL, Changeux JP. Neuronal nicotinic receptors: molecular organization and regulations. Neuropharmacology. 34: 563-82. PMID 7566492 DOI: 10.1016/0028-3908(95)00034-4  1
1995 Changeux JP. Thudichum Medal Lecture. The acetylcholine receptor: a model for allosteric membrane proteins. Biochemical Society Transactions. 23: 195-205. PMID 7545603  1
1995 Bertrand D, Changeux JP. Nicotinic receptor: An allosteric protein specialized for intercellular communication Seminars in the Neurosciences. 7: 75-90. DOI: 10.1006/smns.1995.0010  1
1994 Changeux JP, Andersen P, Berridge MJ, Blakemore C, Bliss T, Gamero AF, Freund T, Grantyn R, Grillner S, Hepp K. European brain research. Nature. 369: 601. PMID 8208281 DOI: 10.1038/369601a0  1
1994 Bessereau JL, Stratford-Perricaudet LD, Piette J, Le Poupon C, Changeux JP. In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus. Proceedings of the National Academy of Sciences of the United States of America. 91: 1304-8. PMID 8108406  0.36
1994 Kerszberg M, Changeux JP. A model for reading morphogenetic gradients: autocatalysis and competition at the gene level. Proceedings of the National Academy of Sciences of the United States of America. 91: 5823-7. PMID 8016073 DOI: 10.1073/pnas.91.13.5823  1
1994 Kerszberg M, Changeux JP. Partners make patterns in morphogenesis. Current Biology : Cb. 4: 1046-7. PMID 7874493 DOI: 10.1016/S0960-9822(00)00240-2  1
1994 Granon S, Vidal C, Thinus-Blanc C, Changeux JP, Poucet B. Working memory, response selection, and effortful processing in rats with medial prefrontal lesions. Behavioral Neuroscience. 108: 883-91. PMID 7826511 DOI: 10.1037/0735-7044.108.5.883  1
1994 Changeux JP, Edelstein SJ. On allosteric mechanisms and acetylcholine receptors. Trends in Biochemical Sciences. 19: 399-400. PMID 7817393 DOI: 10.1016/0968-0004(94)90084-1  1
1994 Galzi JL, Changeux JP. Neurotransmitter-gated ion channels as unconventional allosteric proteins Current Opinion in Structural Biology. 4: 554-565. DOI: 10.1016/S0959-440X(94)90218-6  1
1993 Dehaene S, Changeux JP. Development of elementary numerical abilities: a neuronal model. Journal of Cognitive Neuroscience. 5: 390-407. PMID 23964915 DOI: 10.1162/jocn.1993.5.4.390  1
1993 Aslanian D, Grof P, Galzi JL, Changeux JP. A Raman spectroscopic study of acetylcholine receptor-rich membranes from Torpedo marmorata. Interaction of the receptor with carbamylcholine and (+)-tubocurarine. Biochimica Et Biophysica Acta. 1148: 291-302. PMID 8504123 DOI: 10.1016/0005-2736(93)90142-M  1
1993 Bessis A, Savatier N, Devillers-Thiéry A, Bejanin S, Changeux JP. Negative regulatory elements upstream of a novel exon of the neuronal nicotinic acetylcholine receptor alpha 2 subunit gene. Nucleic Acids Research. 21: 2185-92. PMID 8502560  0.52
1993 Léna C, Changeux JP, Mulle C. Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2680-8. PMID 8501532  0.6
1993 Piette J, Huchet M, Houzelstein D, Changeux JP. Compartmentalized expression of the alpha- and gamma-subunits of the acetylcholine receptor in recently fused myofibers. Developmental Biology. 157: 205-13. PMID 8482411 DOI: 10.1006/dbio.1993.1124  0.64
1993 Hill JA, Zoli M, Bourgeois JP, Changeux JP. Immunocytochemical localization of a neuronal nicotinic receptor: the beta 2-subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 1551-68. PMID 8463835  1
1993 Daubas P, Salmon AM, Zoli M, Geoffroy B, Devillers-Thiéry A, Bessis A, Médevielle F, Changeux JP. Chicken neuronal acetylcholine receptor alpha 2-subunit gene exhibits neuron-specific expression in the brain and spinal cord of transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 2237-41. PMID 8460128  0.6
1993 Quik M, Cook RG, Revah F, Changeux JP, Patrick J. Presence of alpha-cobratoxin and phospholipase A2 activity in thymopoietin preparations. Molecular Pharmacology. 44: 678-9. PMID 8371719  1
1993 Cartaud J, Changeux JP. Post-transcriptional compartmentalization of acetylcholine receptor biosynthesis in the subneural domain of muscle and electrocyte junctions. The European Journal of Neuroscience. 5: 191-202. PMID 8261100  1
1993 Eiselé JL, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature. 366: 479-83. PMID 8247158 DOI: 10.1038/366479a0  1
1993 Changeux JP. Allosteric proteins: from regulatory enzymes to receptors--personal recollections. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 15: 625-34. PMID 8240316 DOI: 10.1002/bies.950150909  1
1993 Changeux JP. Chemical signaling in the brain. Scientific American. 269: 58-62. PMID 8235555  1
1993 Venkatasubramanian K, Audhya T, Goldstein G, Revah F, Mulle C, Pinset C, Changeux JP, Quik M, Babu U. Notice of retraction. Proceedings of the National Academy of Sciences of the United States of America. 90: 10409. PMID 8234308  0.6
1993 Changeux JP. [The chemistry of cerebral communications]. Bulletin De L'AcadéMie Nationale De MéDecine. 177: 1573-85. PMID 7912990  1
1993 Vidal C, Changeux JP. Nicotinic and muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortex in vitro. Neuroscience. 56: 23-32. PMID 7901807 DOI: 10.1016/0306-4522(93)90558-W  1
1993 Bertrand D, Galzi JL, Devillers-Thiéry A, Bertrand S, Changeux JP. Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 6971-5. PMID 7688468  0.44
1993 Léna C, Changeux JP. Allosteric modulations of the nicotinic acetylcholine receptor. Trends in Neurosciences. 16: 181-6. PMID 7685943 DOI: 10.1016/0166-2236(93)90150-K  1
1993 Devillers-Thiéry A, Galzi JL, Eiselé JL, Bertrand S, Bertrand D, Changeux JP. Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels. The Journal of Membrane Biology. 136: 97-112. PMID 7508983 DOI: 10.1007/BF02505755  1
1993 Bertrand D, Galzi JL, Devillers-Thiéry A, Bertrand S, Changeux JP. Stratification of the channel domain in neurotransmitter receptors. Current Opinion in Cell Biology. 5: 688-93. PMID 7504932 DOI: 10.1016/0955-0674(93)90141-C  1
1993 Benoit P, Changeux JP. Voltage dependencies of the effects of chlorpromazine on the nicotinic receptor channel from mouse muscle cell line So18. Neuroscience Letters. 160: 81-4. PMID 7504221 DOI: 10.1016/0304-3940(93)90918-B  1
1992 Bertrand D, Devillers-Thiéry A, Revah F, Galzi JL, Hussy N, Mulle C, Bertrand S, Ballivet M, Changeux JP. Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain. Proceedings of the National Academy of Sciences of the United States of America. 89: 1261-5. PMID 1741378  1
1992 Cartaud A, Ludosky MA, Tomé FM, Collin H, Stetzkowski-Marden F, Khurana TS, Kunkel LM, Fardeau M, Changeux JP, Cartaud J. Localization of dystrophin and dystrophin-related protein at the electromotor synapse and neuromuscular junction in Torpedo marmorata. Neuroscience. 48: 995-1003. PMID 1630633  0.36
1992 Chatrenet B, Kotzba-Hibert F, Mulle C, Changeux JP, Goeldner MP, Hirth C. Photoactivatable agonist of the nicotinic acetylcholine receptor: potential probe to characterize the structural transitions of the acetylcholine binding site in different states of the receptor. Molecular Pharmacology. 41: 1100-6. PMID 1614412  1
1992 Mulle C, Léna C, Changeux JP. Potentiation of nicotinic receptor response by external calcium in rat central neurons. Neuron. 8: 937-45. PMID 1586487 DOI: 10.1016/0896-6273(92)90208-U  1
1992 Epstein HF, Fischman DA, Bader D, Changeux JP, Buckhold K, Ordahl CP, Hoffman E, Kedes LH, Konieczny S, Leinwand LA. Myoblast therapy. Science (New York, N.Y.). 257: 738. PMID 1496388  1
1992 Salmon AM, Changeux JP. Regulation of an acetylcholine receptor LacZ transgene by muscle innervation. Neuroreport. 3: 973-6. PMID 1482767  1
1992 Changeux JP. Functional organisation of the nicotinic acetylcholine receptor. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 314: 89-94. PMID 1422915  1
1992 Changeux JP, Devillers-Thiéry A, Galzi JL, Revah F. The acetylcholine receptor: a model of an allosteric membrane protein mediating intercellular communication. Ciba Foundation Symposium. 164: 66-89; discussion 87. PMID 1395936 DOI: 10.1016/0165-6147(79)90070-1  1
1992 Changeux JP, Devillers-Thiéry A, Galzi JL, Bertrand D. New mutants to explore nicotinic receptor functions. Trends in Pharmacological Sciences. 13: 299-301. PMID 1384213 DOI: 10.1016/0165-6147(92)90094-M  1
1992 Galzi JL, Devillers-Thiéry A, Hussy N, Bertrand S, Changeux JP, Bertrand D. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. Nature. 359: 500-5. PMID 1383829 DOI: 10.1038/359500a0  1
1992 Changeux JP, Duclert A, Sekine S. Calcitonin gene-related peptides and neuromuscular interactions. Annals of the New York Academy of Sciences. 657: 361-78. PMID 1322090  1
1992 Piette J, Huchet M, Duclert A, Fujisawa-Sehara A, Changeux JP. Localization of mRNAs coding for CMD1, myogenin and the alpha-subunit of the acetylcholine receptor during skeletal muscle development in the chicken. Mechanisms of Development. 37: 95-106. PMID 1318730  0.64
1992 Mulle C, Choquet D, Korn H, Changeux JP. Calcium influx through nicotinic receptor in rat central neurons: its relevance to cellular regulation. Neuron. 8: 135-43. PMID 1309647 DOI: 10.1016/0896-6273(92)90115-T  1
1992 Changeux JP, Galzi JL, Devillers-Thiéry A, Bertrand D. The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis. Quarterly Reviews of Biophysics. 25: 395-432. PMID 1293635 DOI: 10.1017/S0033583500004352  1
1992 Devillers-Thiéry A, Galzi JL, Bertrand S, Changeux JP, Bertrand D. Stratified organization of the nicotinic acetylcholine receptor channel. Neuroreport. 3: 1001-4. PMID 1282832  1
1991 Galzi JL, Revah F, Bessis A, Changeux JP. Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain. Annual Review of Pharmacology and Toxicology. 31: 37-72. PMID 2064379 DOI: 10.1146/annurev.pa.31.040191.000345  1
1991 Galzi JL, Revah F, Bouet F, Ménez A, Goeldner M, Hirth C, Changeux JP. Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand. Proceedings of the National Academy of Sciences of the United States of America. 88: 5051-5. PMID 2052586  1
1991 Changeux JP. Serine-specific phosphorylation of nicotinic receptor associated 43K protein Biochemistry. 30: 5579-5585. PMID 2036428  1
1991 Changeux JP. Compartmentalized transcription of acetylcholine receptor genes during motor endplate epigenesis New Biologist. 3: 413-429. PMID 1883810  1
1991 Dehaene S, Changeux JP. The Wisconsin Card Sorting Test: theoretical analysis and modeling in a neuronal network. Cerebral Cortex (New York, N.Y. : 1991). 1: 62-79. PMID 1822726 DOI: 10.1093/cercor/1.1.62  1
1991 Laufer R, Klarsfeld A, Changeux JP. Phorbol esters inhibit the activity of the chicken acetylcholine receptor alpha-subunit gene promoter. Role of myogenic regulators. European Journal of Biochemistry / Febs. 202: 813-8. PMID 1765095  0.6
1991 Galzi JL, Bertrand D, Devillers-Thiéry A, Revah F, Bertrand S, Changeux JP. Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis. Febs Letters. 294: 198-202. PMID 1756861 DOI: 10.1016/0014-5793(91)80668-S  1
1991 Revah F, Bertrand D, Galzi JL, Devillers-Thiéry A, Mulle C, Hussy N, Bertrand S, Ballivet M, Changeux JP. Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor. Nature. 353: 846-9. PMID 1719423 DOI: 10.1038/353846a0  1
1991 Roa M, Changeux JP. Characterization and developmental evolution of a high-affinity binding site for calcitonin gene-related peptide on chick skeletal muscle membrane Neuroscience. 41: 563-570. PMID 1651462 DOI: 10.1016/0306-4522(91)90349-S  1
1991 Changeux JP. Functional organization of the nicotinic acetylcholine receptor European Neuropsychopharmacology. 1: 305-307. DOI: 10.1016/0924-977X(91)90538-6  1
1990 Galzi JL, Revah F, Black D, Goeldner M, Hirth C, Changeux JP. Identification of a novel amino acid alpha-tyrosine 93 within the cholinergic ligands-binding sites of the acetylcholine receptor by photoaffinity labeling. Additional evidence for a three-loop model of the cholinergic ligands-binding sites. The Journal of Biological Chemistry. 265: 10430-7. PMID 2355008  1
1990 Mulle C, Changeux JP. A novel type of nicotinic receptor in the rat central nervous system characterized by patch-clamp techniques Journal of Neuroscience. 10: 169-175. PMID 2299390  1
1990 Changeux JP, Benoît P, Bessis A, Cartaud J, Devillers-Thiéry A, Fontaine B, Galzi JL, Klarsfeld A, Laufer R, Mulle C. Regulation of acetylcholine receptor gene expression by neural factors and electrical activity during motor endplate formation. Biochemical Society Symposium. 56: 9-12. PMID 2256962  1
1990 Changeux JP. The TiPS lecture the nicotinic acetylcholine receptor: an allosteric protein prototype of ligand-gated ion channels Trends in Pharmacological Sciences. 11: 485-492. PMID 2080554 DOI: 10.1016/0165-6147(90)90049-E  1
1990 Changeux JP, Benoit P, Bessis A, Cartaud J, Devillers-Thiery A, Fontaine B, Galzi JL, Klarsfeld A, Laufer R, Mulle C. The acetylcholine receptor: functional architecture and regulation. Advances in Second Messenger and Phosphoprotein Research. 24: 15-9. PMID 1698404  1
1990 Revah F, Galzi JL, Giraudat J, Haumont PY, Lederer F, Changeux JP. The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel. Proceedings of the National Academy of Sciences of the United States of America. 87: 4675-9. PMID 1693775  1
1989 Dehaene S, Changeux JP. A simple model of prefrontal cortex function in delayed-response tasks. Journal of Cognitive Neuroscience. 1: 244-61. PMID 23968508 DOI: 10.1162/jocn.1989.1.3.244  1
1989 Villar MJ, Roa M, Huchet M, Hökfelt T, Changeux JP, Fahrenkrug J, Brown JC, Epstein M, Hersh L. Immunoreactive Calcitonin Gene-Related Peptide, Vasoactive Intestinal Polypeptide, and Somatostatin in Developing Chicken Spinal Cord Motoneurons. The European Journal of Neuroscience. 1: 269-287. PMID 12106158  0.64
1989 Fontaine B, Changeux JP. Localization of nicotinic acetylcholine receptor α-subunit transcripts during myogenesis and motor endplate development in the chick Journal of Cell Biology. 108: 1025-1037. PMID 2921278  1
1989 Vidal C, Changeux JP. Pharmacological profile of nicotinic acetylcholine receptors in the rat prefrontal cortex: An electrophysiological study in a slice preparation Neuroscience. 29: 261-270. PMID 2725858 DOI: 10.1016/0306-4522(89)90056-0  1
1989 Changeux JP, Dehaene S. Neuronal models of cognitive functions. Cognition. 33: 63-109. PMID 2691185 DOI: 10.1016/0010-0277(89)90006-1  1
1989 Laufer R, Changeux JP. Activity-dependent regulation of gene expression in muscle and neuronal cells Molecular Neurobiology. 3: 1-53. PMID 2679765 DOI: 10.1007/BF02935587  1
1989 Laufer R, Changeux JP. Calcitonin gene-related peptide and cyclic AMP stimulate phosphoinositide turnover in skeletal muscle cells. Interaction between two second messenger systems Journal of Biological Chemistry. 264: 2683-2689. PMID 2536720  1
1989 Changeux JP. The acetylcholine receptor: its molecular biology and biotechnological prospects Bioessays. 10: 48-54. PMID 2470366  1
1988 Dehaene S, Changeux JP. Selectionist mechanisms: A framework for interactionism Behavioral and Brain Sciences. 11: 633. DOI: 10.1017/S0140525X00053747  1
1987 Henderson CE, Hauser SL, Huchet M, Dessi F, Hentati F, Taguchi T, Changeux JP, Fardeau M. Extracts of muscle biopsies from patients with spinal muscular atrophies inhibit neurite outgrowth from spinal neurons. Neurology. 37: 1361-4. PMID 3614658  1
1987 Dehaene S, Changeux JP, Nadal JP. Neural networks that learn temporal sequences by selection. Proceedings of the National Academy of Sciences of the United States of America. 84: 2727-31. PMID 3472233  1
1987 Taguchi T, Huchet M, Roa M, Changeux JP, Henderson CE. A subpopulation of embryonic telencephalic neurons survive and develop in vitro in response to factors derived from the periphery. Brain Research. 465: 125-32. PMID 3440197 DOI: 10.1016/0165-3806(87)90234-3  1
1987 Laufer R, Changeux JP. Calcitonin gene-related peptide elevates cyclic AMP levels in chick skeletal muscle: possible neurotrophic role for a coexisting neuronal messenger Embo Journal. 6: 901-906. PMID 3036493  1
1987 Changeux JP, Revah F. The acetylcholine receptor molecule: allosteric sites and the ion channel Trends in Neurosciences. 10: 245-250. DOI: 10.1016/0166-2236(87)90167-6  1
1986 Henderson CE, Benoit P, Huchet M, Guenet JL, Changeux JP. Increase of neurite-promoting activity for spinal neurons in muscles of 'paralysé' mice and tenotomised rats. Brain Research. 390: 65-70. PMID 3948032 DOI: 10.1016/0165-3806(86)90152-5  1
1986 Heidmann T, Changeux JP. Characterization of the transient agonist-triggered state of the acetylcholine receptor rapidly labeled by the noncompetitive blocker [3H]chlorpromazine: Additional evidence for the open channel conformation Biochemistry. 25: 6109-6113. PMID 3790508  1
1986 Hauser SL, Cazenave PA, Lyon-Caen O, Taguchi T, Huchet M, Nuret H, Changeux JP, Henderson CE. Immunoblot analysis of circulating antibodies against muscle proteins in amyotrophic lateral sclerosis and other neurologic diseases. Neurology. 36: 1614-8. PMID 3785679  0.64
1986 Toulouse G, Dehaene S, Changeux JP. Spin glass model of learning by selection. Proceedings of the National Academy of Sciences of the United States of America. 83: 1695-8. PMID 3456609  1
1986 Yeramian E, Changeux JP. A model for long-term changes in synaptic efficacy based upon the interaction of the acetylcholine receptor with the subsynaptic protein of 43,000 daltons Comptes Rendus De L'Academie Des Sciences - Serie Iii. 302: 609-616. PMID 3092997  1
1986 Heidmann O, Buonanno A, Geoffroy B, Robert B, Guénet JL, Merlie JP, Changeux JP. Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse. Science (New York, N.Y.). 234: 866-8. PMID 3022377  1
1986 Changeux JP. Chapter 26 Coexistence of neuronal messengers and molecular selection Progress in Brain Research. 68: 373-403. PMID 2882560 DOI: 10.1016/S0079-6123(08)60252-6  1
1985 Klarsfeld A, Changeux JP. Activity regulates the levels of acetylcholine receptor α-subunit mRNA in cultured chicken myotubes Proceedings of the National Academy of Sciences of the United States of America. 82: 4548-4562. PMID 2989833  1
1984 Benoit P, Delhaye-Bouchaud N, Changeux JP, Mariani J. Stability of multiple innervation of Purkinje cells by climbing fibers in the agranular cerebellum of old rats X-irradiated at birth. Brain Research. 316: 310-3. PMID 6467024  1
1984 Henderson CE, Huchet M, Changeux JP. Neurite-promoting activities for embryonic spinal neurons and their developmental changes in the chick. Developmental Biology. 104: 336-47. PMID 6378691 DOI: 10.1016/0012-1606(84)90089-7  1
1984 Heidmann T, Changeux JP. Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations Proceedings of the National Academy of Sciences of the United States of America. 81: 1897-1901. PMID 6324218  1
1984 Popot JL, Changeux JP. Nicotinic receptor of acetylcholine: Structure of an oligomeric integral membrane protein Physiological Reviews. 64: 1162-1239. PMID 6208568  1
1984 Tzartos SJ, Changeux JP. Lipid-dependent recovery of α-bungarotoxin and monoclonal antibody binding to the purified α-subunit from Torpedo marmorata acetylcholine receptor. Enhancement by noncompetitive channel blockers Journal of Biological Chemistry. 259: 11512-11519. PMID 6088547  1
1983 Tzartos SJ, Changeux JP. High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate Embo Journal. 2: 381-387. PMID 11894953  1
1983 Henderson CE, Huchet M, Changeux JP. Denervation increases a neurite-promoting activity in extracts of skeletal muscle. Nature. 302: 609-11. PMID 6835393 DOI: 10.1038/302609a0  1
1983 Changeux JP. Concluding Remarks: On the "Singularity" of Nerve Cells and its Ontogenesis Progress in Brain Research. 58: 465-478. PMID 6635204 DOI: 10.1016/S0079-6123(08)60049-7  1
1982 Oswald RE, Changeux JP. Crosslinking of α-bungarotoxin to the acetylcholine receptor from Torpedo marmorata by ultraviolet light irradiation Febs Letters. 139: 225-229. PMID 7075777 DOI: 10.1016/0014-5793(82)80857-0  1
1982 Heidmann T, Changeux JP. Molecular model of the regulation of chemical synapse efficiency at the postsynaptic level Comptes Rendus Des Seances De L'Academie Des Sciences - Series Iii. 295: 665-670. PMID 6301652  1
1982 Changeux JP. Regulation of synapse formation in the development of the neuromuscular junction Biology of the Cell. 45: 384.  1
1982 Changeux J, Dennis SG. Signal transduction across cellular membranes Neurosciences Research Program Bulletin. 20: 269-420.  1
1981 Mariani J, Changeux JP. Ontogenesis of olivocerebellar relationships. II. Spontaneous activity of inferior olivary neurons and climbing fibermediated activity of cerebellar Purkinje cells in developing rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 703-9. PMID 7346579  1
1981 Mariani J, Changeux JP. Ontogenesis of olivocerebellar relationships. I. Studies by intracellular recordings of the multiple innervation of Purkinje cells by climbing fibers in the developing rat cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 696-702. PMID 7346578  1
1981 Heidmann T, Changeux JP. Stabilization of the high affinity state of the membrane-bound acetylcholine receptor from Torpedo marmorata by noncompetitive blockers. Evidence for dual interaction and pharmacological selectivity Febs Letters. 131: 239-244. PMID 7297675 DOI: 10.1016/0014-5793(81)80375-4  1
1981 Saitoh T, Changeux JP. Change in state of phosphorylation of acetylcholine receptor during maturation of the electromotor synapse in Torpedo marmorata electric organ Proceedings of the National Academy of Sciences of the United States of America. 78: 4430-4434. PMID 6945595  1
1981 Oswald R, Changeux JP. Ultraviolet light-induced labeling by noncompetitive blockers of the acetylcholine receptor from Torpedo marmorata Proceedings of the National Academy of Sciences of the United States of America. 78: 3925-3929. PMID 6943590  1
1981 Henderson CE, Huchet M, Changeux JP. Neurite outgrowth from embryonic chicken spinal neurons is promoted by media conditioned by muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 2625-9. PMID 6941315  1
1981 Oswald RE, Changeux JP. Selective labeling of the δ subunit of the acetylcholine receptor by a covalent local anesthetic Biochemistry. 20: 7166-7174. PMID 6895603  1
1980 Heidmann T, Changeux JP. Interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata in the millisecond time range: Resolution of an "intermediate" conformational transition and evidence for positive cooperative effects Biochemical and Biophysical Research Communications. 97: 889-896. PMID 7470156 DOI: 10.1016/0006-291X(80)91460-6  1
1980 Mariani J, Changeux JP. [Intracellular recordings of the multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the developing rat]. Comptes Rendus Des SéAnces De L'AcadéMie Des Sciences. SéRie D, Sciences Naturelles. 291: 97-100. PMID 6774831  1
1980 Wennogle LP, Changeux JP. Transmembrane orientation of proteins present in acetylcholine receptor-rich membranes from Torpedo marmorata studied by selective proteolysis European Journal of Biochemistry. 106: 381-393. PMID 6772438  1
1980 Saitoh T, Changeux JP. Phosphorylation in vitro of membrane fragments from Torpedo marmorata electric organ. Effect on membrane solubilization by detergents European Journal of Biochemistry. 105: 51-62. PMID 6245881  1
1980 Mariani J, Changeux JP. Multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the adult staggerer mutant mouse. Journal of Neurobiology. 11: 41-50. PMID 6243692 DOI: 10.1002/neu.480110106  1
1980 Saitoh T, Changeux JP. Factors regulating the susceptibility of the acetylcholine receptor to heat inactivation Journal De Pharmacologie. 11: 108.  1
1979 Heidmann T, Changeux JP. Fast kinetic studies on the allosteric interactions between acetylcholine receptor and local anesthetic binding sites European Journal of Biochemistry. 94: 281-296. PMID 436844  1
1979 Heidmann T, Changeux JP. Fast kinetic studies on the interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata European Journal of Biochemistry. 94: 255-279. PMID 436843  1
1979 Changeux JP. The acetylcholine receptor: an "allosteric" membrane protein Harvey Lectures. 75: 85-254. PMID 400609  1
1979 Betz H, Changeux JP. Regulation of muscle acetylcoline receptor synthesis in vitro by cyclic nucleotide derivatives [20] Nature. 278: 749-752. PMID 219375 DOI: 10.1038/278749a0  1
1979 Changeux JP. Genetic determinism and epigenetic modulation of the synaptic development Psychologie Medicale. 11: 1117-1124.  1
1978 Changeux JP, Mikoshiba K. Genetic and 'Epigenetic' Factors Regulating Synapse Formation in Vertebrate Cerebellum and Neuromuscular Junction Progress in Brain Research. 48: 43-66. PMID 746166 DOI: 10.1016/S0079-6123(08)61015-8  1
1978 Benoit P, Changeux JP. Consequences of blocking the nerve with a local anaesthetic on the evolution of multiinnervation at the regenerating neuromuscular junction of the rat Brain Research. 149: 89-96. PMID 656962 DOI: 10.1016/0006-8993(78)90589-9  1
1978 Mikoshiba K, Changeux JP. Morphological and biochemical studies on isolated molecular and granular layers from bovine cerebellum Brain Research. 142: 487-504. PMID 638747 DOI: 10.1016/0006-8993(78)90911-3  1
1978 Briley MS, Changeux JP. Recovery of some functional properties of the detergent-extracted cholinergic receptor protein from Torpedo marmorata after reintegration into a membrane environment European Journal of Biochemistry. 84: 429-439. PMID 565286  1
1978 Merlie JP, Changeux JP, Gros F. Skeletal muscle acetylcholine receptor. Purification, characterization, and turnover in muscle cell cultures. The Journal of Biological Chemistry. 253: 2882-91. PMID 564910  1
1978 Heidmann T, Changeux JP. Structural and functional properties of the acetylcholine receptor protein in its purified and membrane-bound states Annual Review of Biochemistry. 47: 317-357. PMID 354498  1
1977 Sobel A, Changeux JP. Purification and characterization of the cholinergic receptor protein in its membrane bound and detergent soluble forms from the electric organ of Torpedo marmorata Biochemical Society Transactions. 5: 511-514. PMID 902870  1
1977 Bon C, Changeux JP. Ceruleotoxin: a possible marker of the cholinergic ionophore European Journal of Biochemistry. 74: 43-51. PMID 856574  1
1977 Bon C, Changeux JP. Chemical and pharmacological characterization of toxic polypeptides from the venom of Bungarus caeruleus European Journal of Biochemistry. 74: 31-42. PMID 856573  1
1977 Teichberg VI, Sobel A, Changeux JP. In vitro phosphorylation of the acetylcholine receptor. Nature. 267: 540-2. PMID 559948 DOI: 10.1038/267540a0  1
1977 Briley MS, Changeux JP. Isolation and purification of the nicotinic acetylcholine receptor and its functional reconstitution into a membrane environment International Review of Neurobiology. 20: 31-63. PMID 338528  1
1977 Teichberg VI, Changeux JP. Evidence for protein phosphorylation and dephosphorylation in membrane fragments isolated from the electric organ of Electrophorus electricus. Febs Letters. 74: 71-6. PMID 190043 DOI: 10.1016/0014-5793(77)80755-2  1
1977 Mariani J, Crepel F, Mikoshiba K, Changeux JP, Sotelo C. Anatomical, physiological and biochemical studies of the cerebellum from Reeler mutant mouse. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 281: 1-28. PMID 22882  1
1977 Atlas D, Teichberg VI, Changeux JP. Direct evidence for beta-adrenoreceptors on the Purkinje cells of mouse cerebellum. Brain Research. 128: 532-6. PMID 18258 DOI: 10.1016/0006-8993(77)90178-0  1
1976 Kato G, Changeux JP. Studies on the effect of histrionicotoxin on the monocellular electroplax from Electrophorus electricus on the ending of [3H]acetylcholine to membrane fragments from Torpedo marmorata Molecular Pharmacology. 12: 92-100. PMID 1256447  1
1976 Merlie JP, Changeux JP, Gros F. Acetylcholine receptor degradation measured by pulse chase labelling. Nature. 264: 74-6. PMID 1004540 DOI: 10.1038/264074a0  1
1976 Grünhagen HH, Changeux JP. Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. V. Qualitative correlation between pharmacological effects and equilibration processes of the cholinergic receptor protein as revealed by the structural probe quinacrine Journal of Molecular Biology. 106: 517-535. PMID 978734 DOI: 10.1016/0022-2836(76)90250-3  1
1976 Grünhagen HH, Changeux JP. Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. IV. Quinacrine: a fluorescent probe for the conformational transitions of the cholinergic receptor protein in its membrane-bound state Journal of Molecular Biology. 106: 497-516. PMID 978733 DOI: 10.1016/0022-2836(76)90249-7  1
1976 Moreau M, Changeux JP. Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. I. Pharmacological properties of the electroplaque Journal of Molecular Biology. 106: 457-467. PMID 978730 DOI: 10.1016/0022-2836(76)90246-1  1
1976 Teichberg VI, Changeux JP. Presence of two forms of acetylcholine receptor with different isoelectric points in the electric organ of Electrophorus electricus and their catalytic interconversion in vitro. Febs Letters. 67: 264-8. PMID 964359 DOI: 10.1016/0014-5793(76)80543-1  1
1976 Grünhagen HH, Iwatsubo M, Changeux J. Rapid changes in the intensity of fluorescence observed in the presence of cholinergic agonists with Torpedo marmorata membrane fragments rich in cholinergic receptors and labelled with quinacrine Comptes Rendus Hebdomadaires Des Seances De L"Academie Des Sciences. Serie D: Sciences Naturelles. 283: 1105-1108. PMID 826347  1
1976 Changeux JP, Danchin A. Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks Nature. 264: 705-712. PMID 189195 DOI: 10.1038/264705a0  1
1975 Bon C, Changeux JP. Ceruleotoxin: An acidic neurotoxin from the venom of Bungarus caeruleus which blocks the response to a cholinergic agonist without binding to the cholinergic receptor site Febs Letters. 59: 212-216. PMID 1241677 DOI: 10.1016/0014-5793(75)80377-2  1
1975 Lester HA, Changeux JP, Sheridan RE. Conductance increases produced by bath application of cholinergic agonists to Electrophorus electroplaques. The Journal of General Physiology. 65: 797-816. PMID 1194885  1
1975 Benoit P, Changeux JP. Consequences of tenotomy on the evolution of multiineervation in developing rat soleus muscle Brain Research. 99: 354-358. PMID 1182551 DOI: 10.1016/0006-8993(75)90036-0  1
1975 Sugiyama H, Changeux JP. Interconversion between different states of affinity for acetylcholine of the cholinergic receptor protein from Torpedo marmorata European Journal of Biochemistry. 55: 505-515. PMID 1175609  1
1975 Cohen JB, Changeux JP. The cholinergic receptor protein in its membrane environment. Annual Review of Pharmacology. 15: 83-103. PMID 1096798 DOI: 10.1146/annurev.pa.15.040175.000503  1
1975 Merlie JP, Sobel A, Changeux JP, Gros F. Synthesis of acetylcholine receptor during differentiation of cultured embryonic muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 72: 4028-32. PMID 1060086  1
1975 Grünhagen H, Changeux JP. Structural transitions of the Torpedo cholinergic receptor in its membrane state as demonstrated by a fluorescent local anesthetic: quinacrine Comptes Rendus Hebdomadaires Des Seances De L"Academie Des Sciences. Serie D: Sciences Naturelles. 281: 1047-1050. PMID 813874  1
1975 Brisson AD, Scandella CJ, Bienvenüe A, Devaux PF, Cohen JB, Changeux JP. Interaction of a spin-labeled long chain acylcholine with the cholinergic receptor protein in its membrane environment. Proceedings of the National Academy of Sciences of the United States of America. 72: 1087-91. PMID 165483  0.84
1974 Cohen JB, Weber M, Changeux JP. Effects of local anesthetics and calcium on the interaction of cholinergic ligands with the nicotinic receptor protein from Torpedo marmorata. Molecular Pharmacology. 10: 904-32. PMID 25771543  0.84
1974 Dupont Y, Cohen JB, Changeux JP. X-ray diffraction study of membrane fragments rich in acetylcholine receptor protein prepared from the electric organ of Torpedo marmorata. Febs Letters. 40: 130-3. PMID 4855432  0.84
1974 Meunier JC, Sealock R, Olsen R, Changeux JP. Purification and properties of the cholinergic receptor protein from Electrophorus electricus electric tissue. European Journal of Biochemistry / Febs. 45: 371-94. PMID 4853969  0.52
1974 Weber M, Changeux JP. Binding of Naja nigricollis [3H]α toxin to membrane fragments from Electrophorus and Torpedo electric organs. III. Effects of local anaesthetics on the binding of the tritiated α neurotoxin Molecular Pharmacology. 10: 35-40. PMID 4846183  1
1974 Weber M, Changeux JP. Binding of Naja nigricollis [3H]α toxin to membrane fragments from Electrophorus and Torpedo electric organs. II. Effect of cholinergic agonists and antagonists on the binding of the tritiated α neurotoxin Molecular Pharmacology. 10: 15-34. PMID 4846182  1
1974 Weber M, Changeux JP. Binding of Naja nigricollis [3H]α toxin to membrane fragments from Electrophorus and Torpedo electric organs. I. Binding of the tritiated α neurotoxin in the absence of effector Molecular Pharmacology. 10: 1-14. PMID 4602911  1
1974 Hazelbauer GL, Changeux JP. Reconstitution of a chemically excitable membrane Proceedings of the National Academy of Sciences of the United States of America. 71: 1479-1483. PMID 4524651  1
1974 Sotelo C, Changeux JP. Transsynaptic degeneration 'en cascade' in the cerebellar cortex of staggerer mutant rice Brain Research. 67: 519-526. PMID 4470439 DOI: 10.1016/0006-8993(74)90499-5  1
1974 Cohen JB, Weber M, Changeux JP. [Effect of local anesthetics on the binding properties of cholinergic receptors of the torpedo]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 278: 1269-72. PMID 4276961  0.84
1974 Crepel F, Mariani J, Korn H, Changeux JP. [Electrophysiology of the cerebellar cortex in the staggerer mutant mouse]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 277: 2761-3. PMID 4211422  1
1974 Sotelo C, Changeux JP. Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse Brain Research. 77: 484-491. PMID 4136558 DOI: 10.1016/0006-8993(74)90636-2  1
1974 Gerschenfeld HM, Gros F, Jacob F, Lwoff A, Changeux JP, Masle, Wall P. Academics in Chile [1] Nature. 248: 376. DOI: 10.1038/248376a0  1
1974 Lester HA, Changeux JP. Voltage effects on the activation of acetylcholine receptors as measured by chord conductance Federation Proceedings. 33.  1
1973 Hucho F, Changeux JP. Molecular weight and quaternary structure of the cholinergic receptor protein extracted by detergents from Electrophorus electricus electric tissue. Febs Letters. 38: 11-5. PMID 4772687 DOI: 10.1016/0014-5793(73)80500-9  1
1973 Cohen JB, Changeux JP. Interaction of a fluorescent ligand with membrane-bound cholinergic receptor from Torpedo marmorata. Biochemistry. 12: 4855-64. PMID 4761972  1
1973 Changeux JP. Cholinergic receptors in Electrophorus Neurosciences Research Program Bulletin. 11: 246-252. PMID 4716596  1
1973 Cohen JB, Changeux JP. [Interaction of a fluorescent ligand with the protein receptor of acetylcholine present in Torpedo marmorata membrane fragments]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 277: 603-6. PMID 4205999  1
1973 Meunier JC, Changeux JP. Comparison between the affinities for reversible cholinergic ligands of a purified and membrane bound state of the acetylcholine-receptor protein from Electrophorus electricus Febs Letters. 32: 143-148. PMID 4146034 DOI: 10.1016/0014-5793(73)80758-6  1
1973 Cartaud J, Benedetti EL, Cohen JB, Meunier JC, Changeux JP. Presence of a lattice structure in membrane fragments rich in nicotinic receptor protein from the electric organ of Torpedo marmorata. Febs Letters. 33: 109-13. PMID 4124671  0.84
1972 Meunier JC, Olsen RW, Changeux JP. Studies on the cholinergic receptor protein from Electrophorus electricus. Effect of detergents on some hydrodynamic properties of the receptor protein in solution. Febs Letters. 24: 63-8. PMID 5086619  0.52
1972 Meunier JC, Olsen RW, Menez A, Fromageot P, Boquet P, Changeux JP. Some physical properties of the cholinergic receptor protein from Electrophorus electricus revealed by a tritiated alpha-toxin from Naja nigricollis venom. Biochemistry. 11: 1200-10. PMID 5012974  0.52
1972 Olsen RW, Meunier JC, Changeux JP. Progress in the purification of the cholinergic receptor protein from Electrophorus electricus by affinity chromatography. Febs Letters. 28: 96-100. PMID 4646881  0.52
1972 Cohen JB, Weber M, Huchet M, Changeux JP. Purification from Torpedo marmorata electric tissue of membrane fragments particularly rich in cholinergic receptor protein. Febs Letters. 26: 43-7. PMID 4636749  0.84
1972 Lefever R, Changeux JP. [A theory for sodium ion transport during electric stimulation]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 275: 591-4. PMID 4627977  1
1972 Changeux JP. Studies on the molecular mechanism of the response of an excitable membrane to cholinergic agents Chemistry and Physics of Lipids. 8: 355-365. PMID 4557529 DOI: 10.1016/0009-3084(72)90066-7  1
1972 Kasai M, Changeux JP. Errata The Journal of Membrane Biology. 7: 312. DOI: 10.1007/BF01867922  1
1971 Patrick J, Valeur B, Monnerie L, Changeux JP. Changes in extrinsic fluorescence intensity of the electroplax membrane during electrical excitation. The Journal of Membrane Biology. 5: 102-20. PMID 24172986 DOI: 10.1007/BF01870827  1
1971 Meunier JC, Olsen R, Menez A, Morgat JL, Fromageot P, Ronseray AM, Boquet P, Changeux JP. [Some physical properties of the acetylcholine protein receptor studied with a radioactive neurotoxin]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 273: 595-8. PMID 5001139  0.52
1971 Kasai M, Changeux JP. In vitro excitation of purified membrane fragments by cholinergic agonists - III. Comparison of the dose-response curves to decamethonium with the corresponding binding curves of decamethonium to the cholinergic receptor The Journal of Membrane Biology. 6: 58-80. DOI: 10.1007/BF01874114  1
1971 Kasai M, Changeux JP. In Vitro excitation of purified membrane fragments by cholinergic agonists - II. The permeability change caused by cholinergic agonists The Journal of Membrane Biology. 6: 24-57. DOI: 10.1007/BF01874113  1
1971 Kasai M, Changeux JP. In Vitro excitation of purified membrane fragments by cholinergic agonists - I. Pharmalogical properties of the excitable membrane fragments The Journal of Membrane Biology. 6: 1-23. DOI: 10.1007/BF01874112  1
1970 Blumenthal R, Changeux JP. About the changes of internal ionic concentration in the isolated electroplax during chemical excitation Bba - Biomembranes. 219: 398-404. PMID 5497198 DOI: 10.1016/0005-2736(70)90217-8  1
1970 Valeur B, Patrick J, Podleski T, Monnerie L, Changeux JP. [Perfecting an apparatus allowing to measure changes of extrinsic fluorescence intensit y associated with electric excitation of electroplaque isolated from gymnotus]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 270: 2583-6. PMID 4987648  1
1970 Kasai M, Changeux JP. Demonstration of the excitation by cholinergic agonists from fractions of purified membranes, in vitro Comptes Rendus Hebdomadaires Des Seances De L"Academie Des Sciences. Serie D: Sciences Naturelles. 270: 1400-1403. PMID 4986387  1
1969 Podleski T, Changeux JP. Effects associated with permeability changes caused by Gramicidin A in electroplax membrane Nature. 221: 541-545. PMID 5789298 DOI: 10.1038/221541a0  1
1969 Meunier JC, Changeux JP. On the irreversible binding of p-(trimethylammonium) benzenediazonium fluoroborate (TDF) to acetylcholinesterase from electrogenic tissue Febs Letters. 2: 224-226.  1
1968 Changeux JP, Podleski TR. On the excitability and cooperativity of the electroplax membrane Proceedings of the National Academy of Sciences of the United States of America. 59: 944-950. PMID 5238676  1
1968 Changeux JP. Allosteric interactions in aspartate transcarbamylase. III. Interpretation of experimental data in terms of the model of monod, wyman, and changeux Biochemistry. 7: 553-561. PMID 4868541  1
1968 Changeux JP, Gerhart JC, Schachman HK. Allosteric interactions in aspartate transcarbamylase. I. Binding of specific ligands to the native enzyme and its isolated subunits. Biochemistry. 7: 531-8. PMID 4868539  1
1967 Changeux JP, Thiéry J. On the mode of action of colicins: A model of regulation at the membrane level Journal of Theoretical Biology. 17: 315-318. PMID 6073705  1
1967 Podleski T, Changeux JP. Electrical phenomena associated with the activity of the membrane-bound acetylcholinesterase Science. 157: 1579-1581. PMID 6038174  1
1966 Rubin MM, Changeux JP. On the nature of allosteric transitions: Implications of non-exclusive ligand binding Journal of Molecular Biology. 21: 265-274. PMID 5972463  1
1966 Changeux JP. Responses of acetylcholinesterase from Torpedo marmorata to salts and curarizing drugs Molecular Pharmacology. 2: 369-392. PMID 5970686  1
1966 Sanchez C, Changeux JP. On the properties of biosynthetic L-threonine desaminase of a mutant of E. coli K 12 Bulletin De La Societe De Chimie Biologique. 48: 705-713. PMID 5331299  1
1966 Changeux JP. Effects of ionic forces and curarizing agents on the acetylcholine esterase properties of the electric tissue of Torpedo marmorata Comptes Rendus Hebdomadaires Des Seances De L"Academie Des Sciences. Serie D: Sciences Naturelles. 262: 937-940. PMID 4956272  1
1965 CHANGEUX JP. ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHESIZED L-THREONINE DEAMINASE. VI. GENERAL DISCUSSION Bulletin De La SociéTé De Chimie Biologique. 47: 281-300. PMID 14337115  1
1965 CHANGEUX JP. ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHESIZED L-THREONINE DEAMINASE Bulletin De La SociéTé De Chimie Biologique. 47: 267-280. PMID 14337114  1
1965 CHANGEUX JP. ON THE ALLOSTERIC OF BIOSYNTHESIZED L-THREONINE DEAMINASE. IV. THE Bulletin De La SociéTé De Chimie Biologique. 47: 113-139. PMID 14334804  1
1965 CHANGEUX JP. THE CONTROL OF BIOCHEMICAL REACTIONS Scientific American. 212: 36-45. PMID 14261524  1
1964 CHANGEUX JP. ALLOSTERIC INTERACTIONS INTERPRETED IN TERMS OF QUATERNARY STRUCTURE Brookhaven Symposia in Biology. 17: 232-249. PMID 14246265  1
1964 CHANGEUX JP. ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHETIC L-THREONINE DEAMINASE. II Bulletin De La SociéTé De Chimie Biologique. 46: 947-961. PMID 14222206  1
1964 CHANGEUX JP. ON THE ALLOSTERIC PROPERTIES OF L-THREONINE DEAMINASE. I. METHODS OF Bulletin De La SociéTé De Chimie Biologique. 46: 927-946. PMID 14222205  1
1964 CHANGEUX JP. ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHETIC L-THREONINE DEAMINASE. 3 Bulletin De La SociéTé De Chimie Biologique. 46: 1151-1173. PMID 14220121  1
1963 MONOD J, CHANGEUX JP, JACOB F. Allosteric proteins and cellular control systems. Journal of Molecular Biology. 6: 306-29. PMID 13936070  0.76
1962 CHANGEUX JP. Effect of L-threonine and L-isoleucine analogs on L-threonine desaminase Journal of Molecular Biology. 4: 220-225. PMID 13878123  1
1961 CHANGEUX JP. The feedback control mechanisms of biosynthetic L-threonine deaminase by L-isoleucine Cold Spring Harbor Symposia On Quantitative Biology. 26: 313-318. PMID 13878122  1
1960 CHANGEUX JP. On the biochemical expression of genetic determinants of Escherichia coli introduced to Salmonella typhimurium Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. 250: 1575-1577. PMID 13809173  1
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