Wassim Abou-Kheir, Ph.D. - Publications

Affiliations: 
2007 Yeshiva University, New York, NY, United States 
Area:
Cell Biology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Liu YN, Chen WY, Liu MK, Yeh HL, Chen WH, Jiang KC, Li HR, Chen ZQ, Wang WH, Abou-Kheir W, Wen YC. Immunosuppressive role of BDNF in therapy-induced neuroendocrine prostate cancer. Molecular Oncology. PMID 38381121 DOI: 10.1002/1878-0261.13614  0.352
2021 El-Soussi S, Hanna R, Semaan H, Khater AR, Abdallah J, Abou-Kheir W, Abou-Antoun T. A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells Differential Expression of Tumorigenic Proteins. Frontiers in Pediatrics. 9: 693145. PMID 34422720 DOI: 10.3389/fped.2021.693145  0.307
2021 Bahmad HF, Jalloul M, Azar J, Moubarak MM, Samad TA, Mukherji D, Al-Sayegh M, Abou-Kheir W. Tumor Microenvironment in Prostate Cancer: Toward Identification of Novel Molecular Biomarkers for Diagnosis, Prognosis, and Therapy Development. Frontiers in Genetics. 12: 652747. PMID 33841508 DOI: 10.3389/fgene.2021.652747  0.337
2021 Jaafar L, Fakhoury I, Saab S, El-Hajjar L, Abou-Kheir W, El-Sibai M. StarD13 differentially regulates migration and invasion in prostate cancer cells. Human Cell. PMID 33420961 DOI: 10.1007/s13577-020-00479-8  0.348
2020 Cheaito K, Bahmad HF, Jalloul H, Hadadeh O, Msheik H, El-Hajj A, Mukherji D, Al-Sayegh M, Abou-Kheir W. Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids. Frontiers in Cell and Developmental Biology. 8: 571677. PMID 33195205 DOI: 10.3389/fcell.2020.571677  0.353
2020 Bou-Gharios J, Assi S, Bahmad HF, Kharroubi H, Araji T, Chalhoub RM, Ballout F, Harati H, Fares Y, Abou-Kheir W. The potential use of tideglusib as an adjuvant radio-therapeutic treatment for glioblastoma multiforme cancer stem-like cells. Pharmacological Reports : Pr. PMID 33140310 DOI: 10.1007/s43440-020-00180-5  0.32
2020 Bahmad HF, Elajami MK, Daouk R, Jalloul H, Darwish B, Chalhoub RM, Assi S, Chamaa F, Abou-Kheir W. Stem Cells: In Sickness and in Health. Current Stem Cell Research & Therapy. PMID 32867660 DOI: 10.2174/1574888X15999200831160710  0.374
2020 Ballout F, Monzer A, Fatfat M, Ouweini HE, Jaffa MA, Abdel-Samad R, Darwiche N, Abou-Kheir W, Gali-Muhtasib H. Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells. Oncotarget. 11: 2959-2972. PMID 32821342 DOI: 10.18632/Oncotarget.27426  0.425
2020 Daouk R, Bahmad HF, Saleh E, Monzer A, Ballout F, Kadara H, Abou-Kheir W. Genome-wide gene expression analysis of a murine model of prostate cancer progression: Deciphering the roles of IL-6 and p38 MAPK as potential therapeutic targets. Plos One. 15: e0237442. PMID 32790767 DOI: 10.1371/Journal.Pone.0237442  0.401
2020 Bahmad HF, Peng W, Zhu R, Ballout F, Monzer A, Elajami MK, Kobeissy F, Abou-Kheir W, Mechref Y. Protein Expression Analysis of an In Vitro Murine Model of Prostate Cancer Progression: Towards Identification of High-Potential Therapeutic Targets. Journal of Personalized Medicine. 10. PMID 32784957 DOI: 10.3390/Jpm10030083  0.384
2020 Bahmad HF, Abou-Kheir W. Crosstalk between COVID-19 and prostate cancer. Prostate Cancer and Prostatic Diseases. PMID 32709978 DOI: 10.1038/S41391-020-0262-Y  0.377
2020 Al Matari N, Deeb G, Mshiek H, Sinjab A, Kadara H, Abou-Kheir W, Mhanna R. Anti-Tumor Effects of Biomimetic Sulfated Glycosaminoglycans on Lung Adenocarcinoma Cells in 2D and 3D In Vitro Models. Molecules (Basel, Switzerland). 25. PMID 32503108 DOI: 10.3390/Molecules25112595  0.414
2020 Msheik H, Azar J, El Sabeh M, Abou-Kheir W, Daoud G. HTR-8/SVneo: A model for epithelial to mesenchymal transition in the human placenta. Placenta. 90: 90-97. PMID 32056558 DOI: 10.1016/J.Placenta.2019.12.013  0.362
2020 Bahmad HF, Elajami MK, El Zarif T, Bou-Gharios J, Abou-Antoun T, Abou-Kheir W. Drug repurposing towards targeting cancer stem cells in pediatric brain tumors. Cancer Metastasis Reviews. PMID 31919619 DOI: 10.1007/S10555-019-09840-2  0.356
2020 Hanna R, Daouk R, Ballout F, El-Soussie S, Abdallah J, Abou-Kheir W, Abou-Antoun TM. Abstract 3797: Anti-cancer effects of novel imipridone DRD2 antagonists in a panel of human cancer cell lines Cancer Research. 80: 3797-3797. DOI: 10.1158/1538-7445.Am2020-3797  0.455
2019 Msheik H, El Hayek S, Bari MF, Azar J, Abou-Kheir W, Kobeissy F, Vatish M, Daoud G. Transcriptomic Profiling of Trophoblast Fusion Using BeWo and JEG-3 Cell Lines. Molecular Human Reproduction. PMID 31778538 DOI: 10.1093/Molehr/Gaz061  0.357
2019 Malaeb W, Bahmad HF, Abou-Kheir W, Mhanna R. The sulfation of biomimetic glycosaminoglycan substrates controls binding of growth factors and subsequent neural and glial cell growth. Biomaterials Science. PMID 31407727 DOI: 10.1039/C9Bm00964G  0.308
2019 Darwish B, Chamaa F, Al-Chaer ED, Saadé NE, Abou-Kheir W. Intranigral Injection of Endotoxin Suppresses Proliferation of Hippocampal Progenitor Cells. Frontiers in Neuroscience. 13: 687. PMID 31333405 DOI: 10.3389/Fnins.2019.00687  0.313
2019 Bahmad HF, Chamaa F, Assi S, Chalhoub RM, Abou-Antoun T, Abou-Kheir W. Cancer Stem Cells in Neuroblastoma: Expanding the Therapeutic Frontier. Frontiers in Molecular Neuroscience. 12: 131. PMID 31191243 DOI: 10.3389/Fnmol.2019.00131  0.384
2019 Daouk R, Hassane M, Bahmad HF, Sinjab A, Fujimoto J, Abou-Kheir W, Kadara H. Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From -Deficient Murine Lung Adenocarcinoma With Somatic Mutations. Frontiers in Oncology. 9: 207. PMID 31001473 DOI: 10.3389/Fonc.2019.00207  0.387
2019 Bodgi L, Bahmad HF, Araji T, Al Choboq J, Bou-Gharios J, Cheaito K, Zeidan YH, Eid T, Geara F, Abou-Kheir W. Assessing Radiosensitivity of Bladder Cancer : A 2D vs. 3D Approach. Frontiers in Oncology. 9: 153. PMID 30941305 DOI: 10.3389/Fonc.2019.00153  0.366
2019 Cheaito KA, Bahmad HF, Hadadeh O, Saleh E, Dagher C, Hammoud MS, Shahait M, Mrad ZA, Nassif S, Tawil A, Bulbul M, Khauli R, Wazzan W, Nasr R, Shamseddine A, ... ... Abou-Kheir W, et al. EMT Markers in Locally-Advanced Prostate Cancer: Predicting Recurrence? Frontiers in Oncology. 9: 131. PMID 30915272 DOI: 10.3389/Fonc.2019.00131  0.352
2019 Bahmad HF, Samman H, Monzer A, Hadadeh O, Cheaito K, Abdel-Samad R, Hayar B, Pisano C, Msheik H, Liu YN, Darwiche N, Abou-Kheir W. The synthetic retinoid ST1926 attenuates prostate cancer growth and potentially targets prostate cancer stem-like cells. Molecular Carcinogenesis. PMID 30883933 DOI: 10.1002/Mc.23004  0.483
2018 Bahmad HF, Mouhieddine TH, Chalhoub RM, Assi S, Araji T, Chamaa F, Itani MM, Nokkari A, Kobeissy F, Daoud G, Abou-Kheir W. The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma. Oncotarget. 9: 33549-33561. PMID 30323898 DOI: 10.18632/Oncotarget.26088  0.433
2018 Bahmad HF, Cheaito K, Chalhoub RM, Hadadeh O, Monzer A, Ballout F, El-Hajj A, Mukherji D, Liu YN, Daoud G, Abou-Kheir W. Sphere-Formation Assay: Three-Dimensional Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells. Frontiers in Oncology. 8: 347. PMID 30211124 DOI: 10.3389/Fonc.2018.00347  0.445
2018 Siu MK, Abou-Kheir W, Yin JJ, Chang YS, Barrett B, Suau F, Casey O, Chen WY, Fang L, Hynes P, Hsieh YY, Liu YN, Huang J, Kelly K. Correction: Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance. Oncotarget. 9: 32403. PMID 30190798 DOI: 10.18632/Oncotarget.26020  0.348
2018 Chamaa F, Bahmad HF, Makkawi AK, Chalhoub RM, Al-Chaer ED, Bikhazi GB, Nahas Z, Abou-Kheir W. Nitrous Oxide Induces Prominent Cell Proliferation in Adult Rat Hippocampal Dentate Gyrus. Frontiers in Cellular Neuroscience. 12: 135. PMID 29867368 DOI: 10.3389/Fncel.2018.00135  0.315
2018 Tsai YC, Chen WY, Abou-Kheir W, Zeng T, Yin JJ, Bahmad H, Lee YC, Liu YN. Androgen deprivation therapy-induced epithelial-mesenchymal transition of prostate cancer through downregulating SPDEF and activating CCL2. Biochimica Et Biophysica Acta. PMID 29477409 DOI: 10.1016/J.Bbadis.2018.02.016  0.433
2018 Tsai YC, Zeng T, Abou-Kheir W, Yeh HL, Yin JJ, Lee YC, Chen WY, Liu YN. Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer. Molecular Cancer. 17: 42. PMID 29455655 DOI: 10.1186/S12943-018-0785-1  0.375
2018 Cheaito KA, Hadadeh O, Bahmad H, El-Sabban M, El-Hajj A, Mukherji D, Abou-Kheir W. Abstract B090: Personalized research: Establishment and characterization of prostate cancer patient-derived organoids and cells Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-B090  0.447
2018 Ballout FR, Fatfat M, Abdel-Samad R, Darwiche N, Schneider-Stock R, Abou-Kheir W, Muhtasib H. Abstract 170: Targeting colorectal cancer stem cells with the anticancer molecule thymoquinone Cancer Research. 78: 170-170. DOI: 10.1158/1538-7445.Am2018-170  0.43
2017 Bilani N, Bahmad H, Abou-Kheir W. Prostate Cancer and Aspirin Use: Synopsis of the Proposed Molecular Mechanisms. Frontiers in Pharmacology. 8: 145. PMID 28377721 DOI: 10.3389/Fphar.2017.00145  0.389
2017 Bahmad H, Hadadeh O, Chamaa F, Cheaito K, Darwish B, Makkawi AK, Abou-Kheir W. Modeling Human Neurological and Neurodegenerative Diseases: From Induced Pluripotent Stem Cells to Neuronal Differentiation and Its Applications in Neurotrauma. Frontiers in Molecular Neuroscience. 10: 50. PMID 28293168 DOI: 10.3389/Fnmol.2017.00050  0.353
2017 Katerji M, Barada K, Jomaa M, Kobeissy F, Makkawi AK, Abou-Kheir W, Usta J. Chemosensitivity of U251 Cells to the Co-treatment of D-Penicillamine and Copper: Possible Implications on Wilson Disease Patients. Frontiers in Molecular Neuroscience. 10: 10. PMID 28197071 DOI: 10.3389/Fnmol.2017.00010  0.308
2017 Abou-Kheir W, Barrak J, Hadadeh O, Daoud G. HTR-8/SVneo cell line contains a mixed population of cells. Placenta. 50: 1-7. PMID 28161053 DOI: 10.1016/J.Placenta.2016.12.007  0.371
2016 Daoud G, Monzer A, Bahmad H, Chamaa F, Hamdar L, Mouhieddine TH, Shayya S, Eid A, Kobeissy F, Liu YN, Abou-Kheir W. Primary versus castration‑resistant prostate cancer: modeling through novel murine prostate cancer cell lines. Oncotarget. PMID 27036046 DOI: 10.18632/Oncotarget.8436  0.46
2016 Barrak J, Msheik H, Abou-Kheir W, Daoud G. Assessment of different trophoblast cell lines as in vitro models for placental development Placenta. 45: 106. DOI: 10.1016/J.Placenta.2016.06.157  0.32
2015 Mouhieddine TH, Nokkari A, Itani MM, Chamaa F, Bahmad H, Monzer A, El-Merahbi R, Daoud G, Eid A, Kobeissy FH, Abou-Kheir W. Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells. Frontiers in Neuroscience. 9: 442. PMID 26635517 DOI: 10.3389/Fnins.2015.00442  0.422
2015 Agarwal S, Hynes PG, Tillman HS, Lake R, Abou-Kheir WG, Fang L, Casey OM, Ameri AH, Martin PL, Yin JJ, Iaquinta PJ, Karthaus WR, Clevers HC, Sawyers CL, Kelly K. Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors. Cell Reports. 13: 2147-58. PMID 26628377 DOI: 10.1016/J.Celrep.2015.10.077  0.309
2015 Abou-Kheir W, Eid A, El-Merahbi R, Assaf R, Daoud G. A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells. Plos One. 10: e0139939. PMID 26430881 DOI: 10.1371/Journal.Pone.0139939  0.396
2015 Nokkari A, Mouhieddine TH, Itani MM, Abou-Kheir W, Daoud G, Zhu R, Meshref Y, Soueid J, Al Hariri M, Mondello S, Jaffa AA, Kobeissy F. Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment. Plos One. 10: e0128601. PMID 26047500 DOI: 10.1371/Journal.Pone.0128601  0.34
2015 Chen WY, Liu SY, Chang YS, Yin JJ, Yeh HL, Mouhieddine TH, Hadadeh O, Abou-Kheir W, Liu YN. MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer. Oncotarget. 6: 441-57. PMID 25436980 DOI: 10.18632/Oncotarget.2690  0.365
2014 El-Merahbi R, Liu YN, Eid A, Daoud G, Hosry L, Monzer A, Mouhieddine TH, Hamade A, Najjar F, Abou-Kheir W. Berberis libanotica Ehrenb extract shows anti-neoplastic effects on prostate cancer stem/progenitor cells. Plos One. 9: e112453. PMID 25380390 DOI: 10.1371/Journal.Pone.0112453  0.458
2014 Siu MK, Abou-Kheir W, Yin JJ, Chang YS, Barrett B, Suau F, Casey O, Chen WY, Fang L, Hynes P, Hsieh YY, Liu YN, Huang J, Kelly K. Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance. Oncotarget. 5: 3770-84. PMID 25004126 DOI: 10.18632/Oncotarget.1994  0.379
2014 Abou-Kheir W, Mouhieddine TH, Itani MM, Liu Y. Bone metastatic prostate cancer and resistance to tyrosine kinase inhibitors: an intimate relationship between loss of miR-203 and up-regulation of EGFR signaling Rna & Disease. 1. DOI: 10.14800/Rd.345  0.359
2013 Liu YN, Yin JJ, Abou-Kheir W, Hynes PG, Casey OM, Fang L, Yi M, Stephens RM, Seng V, Sheppard-Tillman H, Martin P, Kelly K. MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms Oncogene. 32: 296-306. PMID 22370643 DOI: 10.1038/Onc.2012.58  0.304
2012 Casey OM, Fang L, Hynes PG, Abou-Kheir WG, Martin PL, Tillman HS, Petrovics G, Awwad HO, Ward Y, Lake R, Zhang L, Kelly K. TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation. Plos One. 7: e41668. PMID 22860005 DOI: 10.1371/journal.pone.0041668  0.329
2012 Liu YN, Abou-Kheir W, Yin JJ, Fang L, Hynes P, Casey O, Hu D, Wan Y, Seng V, Sheppard-Tillman H, Martin P, Kelly K. Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor β-initiated prostate cancer epithelial-mesenchymal transition. Molecular and Cellular Biology. 32: 941-53. PMID 22203039 DOI: 10.1128/Mcb.06306-11  0.409
2012 Abou-Kheir W, Hynes P, Martin P, Yin J, Liu Y, Seng V, Lake R, Spurrier J, Kelly K. Abstract C66: Establishing clinically relevant in vitro models of prostate cancer Cancer Research. 72. DOI: 10.1158/1538-7445.Prca2012-C66  0.455
2012 Liu Y, Yin JJ, Abou-Kheir W, Hynes P, Casey O, Martin P, Kathleen K. Abstract B53: MiR-1 inhibits EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms Cancer Research. 72. DOI: 10.1158/1538-7445.Prca2012-B53  0.323
2012 Liu Y, Martin P, Kelly K, Yin JJ, Abou-Kheir W, Hynes P, Fang L, Casey O, Yi M, Seng V, Tillman H. Abstract A34: Critical and reciprocal regulation of SLUG-KLF4 and SLUG-miR-1/miR-200b in TGFβ-initiated prostate cancer EMT Cancer Research. 72. DOI: 10.1158/1538-7445.Prca2012-A34  0.359
2011 Abou-Kheir W, Hynes PG, Martin P, Yin JJ, Liu YN, Seng V, Lake R, Spurrier J, Kelly K. Self-renewing Pten-/- TP53-/- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity. Plos One. 6: e26112. PMID 22022528 DOI: 10.1371/Journal.Pone.0026112  0.47
2011 Martin P, Liu YN, Pierce R, Abou-Kheir W, Casey O, Seng V, Camacho D, Simpson RM, Kelly K. Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition. The American Journal of Pathology. 179: 422-35. PMID 21703421 DOI: 10.1016/J.Ajpath.2011.03.035  0.405
2010 Abou-Kheir WG, Hynes PG, Martin PL, Pierce R, Kelly K. Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model. Stem Cells (Dayton, Ohio). 28: 2129-40. PMID 20936707 DOI: 10.1002/stem.538  0.345
2009 Dovas A, Gevrey JC, Grossi A, Park H, Abou-Kheir W, Cox D. Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages. Journal of Cell Science. 122: 3873-82. PMID 19808890 DOI: 10.1242/Jcs.051755  0.492
2008 Abou-Kheir W, Isaac B, Yamaguchi H, Cox D. Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2. Journal of Cell Science. 121: 379-90. PMID 18198193 DOI: 10.1242/Jcs.010272  0.485
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