Rasika M. Harshey - Publications

Affiliations: 
University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Molecular Biology, Microbiology Biology

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Partridge JD, Nhu NTQ, Dufour YS, Harshey RM. Tumble Suppression Is a Conserved Feature of Swarming Motility. Mbio. 11. PMID 32546625 DOI: 10.1128/Mbio.01189-20  0.302
2020 Partridge JD, Harshey RM. Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series. Journal of Visualized Experiments : Jove. PMID 32449734 DOI: 10.3791/61364  0.302
2020 Walker DM, Freddolino PL, Harshey RM. A Well-Mixed E. coli Genome: Widespread Contacts Revealed by Tracking Mu Transposition. Cell. PMID 32059782 DOI: 10.1016/J.Cell.2020.01.031  0.337
2019 Partridge JD, Nhu NTQ, Dufour YS, Harshey RM. Remodels the Chemotaxis Pathway for Swarming. Mbio. 10. PMID 30890609 DOI: 10.1128/Mbio.00316-19  0.326
2018 Bhattacharyya S, Soniat MM, Walker D, Jang S, Finkelstein IJ, Harshey RM. Phage Mu Gam protein promotes NHEJ in concert with ligase. Proceedings of the National Academy of Sciences of the United States of America. PMID 30487222 DOI: 10.1073/Pnas.1816606115  0.492
2015 Jang S, Harshey RM. Repair of transposable phage Mu DNA insertions begins only when the E. coli replisome collides with the transpososome. Molecular Microbiology. 97: 746-58. PMID 25983038 DOI: 10.1111/Mmi.13061  0.453
2015 Lee J, Monzingo AF, Keatinge-Clay AT, Harshey RM. Structure of Salmonella FlhE, conserved member of a flagellar type III secretion operon. Journal of Molecular Biology. 427: 1254-62. PMID 25545591 DOI: 10.1016/J.Jmb.2014.11.022  0.306
2014 Harshey RM. Transposable Phage Mu. Microbiology Spectrum. 2. PMID 26104374 DOI: 10.1128/Microbiolspec.Mdna3-0007-2014  0.444
2014 Choi W, Saha RP, Jang S, Harshey RM. Controlling DNA degradation from a distance: a new role for the Mu transposition enhancer. Molecular Microbiology. 94: 595-608. PMID 25256747 DOI: 10.1111/Mmi.12781  0.497
2014 Choi W, Jang S, Harshey RM. Mu transpososome and RecBCD nuclease collaborate in the repair of simple Mu insertions. Proceedings of the National Academy of Sciences of the United States of America. 111: 14112-7. PMID 25197059 DOI: 10.1073/Pnas.1407562111  0.468
2013 Saha RP, Lou Z, Meng L, Harshey RM. Transposable prophage Mu is organized as a stable chromosomal domain of E. coli. Plos Genetics. 9: e1003902. PMID 24244182 DOI: 10.1371/Journal.Pgen.1003902  0.395
2013 Partridge JD, Harshey RM. Swarming: flexible roaming plans. Journal of Bacteriology. 195: 909-18. PMID 23264580 DOI: 10.1128/Jb.02063-12  0.307
2013 Partridge JD, Harshey RM. More than motility: Salmonella flagella contribute to overriding friction and facilitating colony hydration during swarming. Journal of Bacteriology. 195: 919-29. PMID 23264575 DOI: 10.1128/Jb.02064-12  0.322
2012 Harshey RM. The Mu story: how a maverick phage moved the field forward. Mobile Dna. 3: 21. PMID 23217166 DOI: 10.1186/1759-8753-3-21  0.412
2012 Jang S, Sandler SJ, Harshey RM. Mu insertions are repaired by the double-strand break repair pathway of Escherichia coli. Plos Genetics. 8: e1002642. PMID 22511883 DOI: 10.1371/Journal.Pgen.1002642  0.442
2012 Lazova MD, Butler MT, Shimizu TS, Harshey RM. Salmonella chemoreceptors McpB and McpC mediate a repellent response to L-cystine: a potential mechanism to avoid oxidative conditions. Molecular Microbiology. 84: 697-711. PMID 22486902 DOI: 10.1111/J.1365-2958.2012.08051.X  0.308
2012 Lee J, Harshey RM. Loss of FlhE in the flagellar Type III secretion system allows proton influx into Salmonella and Escherichia coli. Molecular Microbiology. 84: 550-65. PMID 22435757 DOI: 10.1111/J.1365-2958.2012.08043.X  0.32
2011 Ge J, Lou Z, Cui H, Shang L, Harshey RM. Analysis of phage Mu DNA transposition by whole-genome Escherichia coli tiling arrays reveals a complex relationship to distribution of target selection protein B, transcription and chromosome architectural elements. Journal of Biosciences. 36: 587-601. PMID 21857106 DOI: 10.1007/S12038-011-9108-Z  0.427
2010 Paul K, Nieto V, Carlquist WC, Blair DF, Harshey RM. The c-di-GMP binding protein YcgR controls flagellar motor direction and speed to affect chemotaxis by a "backstop brake" mechanism. Molecular Cell. 38: 128-39. PMID 20346719 DOI: 10.1016/J.Molcel.2010.03.001  0.32
2010 Ge J, Lou Z, Harshey RM. Immunity of replicating Mu to self-integration: a novel mechanism employing MuB protein. Mobile Dna. 1: 8. PMID 20226074 DOI: 10.1186/1759-8753-1-8  0.383
2010 Choi W, Harshey RM. DNA repair by the cryptic endonuclease activity of Mu transposase. Proceedings of the National Academy of Sciences of the United States of America. 107: 10014-9. PMID 20167799 DOI: 10.1073/Pnas.0912615107  0.493
2008 Ge J, Harshey RM. Congruence of in vivo and in vitro insertion patterns in hot E. coli gene targets of transposable element Mu: opposing roles of MuB in target capture and integration. Journal of Molecular Biology. 380: 598-607. PMID 18556020 DOI: 10.1016/J.Jmb.2008.05.032  0.384
2008 Attmannspacher U, Scharf BE, Harshey RM. FliL is essential for swarming: motor rotation in absence of FliL fractures the flagellar rod in swarmer cells of Salmonella enterica. Molecular Microbiology. 68: 328-41. PMID 18284590 DOI: 10.1111/J.1365-2958.2008.06170.X  0.32
2007 Norris V, den Blaauwen T, Doi RH, Harshey RM, Janniere L, Jiménez-Sánchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Misevic G, Ripoll C, Saier M, Skarstad K, Thellier M. Toward a hyperstructure taxonomy. Annual Review of Microbiology. 61: 309-29. PMID 17896876 DOI: 10.1146/Annurev.Micro.61.081606.103348  0.37
2007 Yin Z, Suzuki A, Lou Z, Jayaram M, Harshey RM. Interactions of phage Mu enhancer and termini that specify the assembly of a topologically unique interwrapped transpososome. Journal of Molecular Biology. 372: 382-96. PMID 17669422 DOI: 10.1016/J.Jmb.2007.06.086  0.607
2007 Norris V, den Blaauwen T, Cabin-Flaman A, Doi RH, Harshey R, Janniere L, Jimenez-Sanchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Saier M, Skarstad K. Functional taxonomy of bacterial hyperstructures. Microbiology and Molecular Biology Reviews : Mmbr. 71: 230-53. PMID 17347523 DOI: 10.1128/Mmbr.00035-06  0.4
2006 Harshey RM, Jayaram M. The mu transpososome through a topological lens. Critical Reviews in Biochemistry and Molecular Biology. 41: 387-405. PMID 17092824 DOI: 10.1080/10409230600946015  0.476
2006 Au TK, Agrawal P, Harshey RM. Chromosomal integration mechanism of infecting mu virion DNA. Journal of Bacteriology. 188: 1829-34. PMID 16484193 DOI: 10.1128/Jb.188.5.1829-1834.2006  0.416
2005 Yin Z, Harshey RM. Enhancer-independent Mu transposition from two topologically distinct synapses. Proceedings of the National Academy of Sciences of the United States of America. 102: 18884-9. PMID 16380426 DOI: 10.1073/Pnas.0506873102  0.597
2005 Wang Q, Suzuki A, Mariconda S, Porwollik S, Harshey RM. Sensing wetness: a new role for the bacterial flagellum. The Embo Journal. 24: 2034-42. PMID 15889148 DOI: 10.1038/Sj.Emboj.7600668  0.328
2005 Yin Z, Jayaram M, Pathania S, Harshey RM. The Mu transposase interwraps distant DNA sites within a functional transpososome in the absence of DNA supercoiling. The Journal of Biological Chemistry. 280: 6149-56. PMID 15563455 DOI: 10.1074/Jbc.M411679200  0.724
2004 Au TK, Pathania S, Harshey RM. True reversal of Mu integration. The Embo Journal. 23: 3408-20. PMID 15282550 DOI: 10.1038/Sj.Emboj.7600344  0.625
2003 Lee I, Harshey RM. Patterns of sequence conservation at termini of long terminal repeat (LTR) retrotransposons and DNA transposons in the human genome: lessons from phage Mu. Nucleic Acids Research. 31: 4531-40. PMID 12888514 DOI: 10.1093/Nar/Gkg499  0.596
2003 Pathania S, Jayaram M, Harshey RM. A unique right end-enhancer complex precedes synapsis of Mu ends: the enhancer is sequestered within the transpososome throughout transposition. The Embo Journal. 22: 3725-36. PMID 12853487 DOI: 10.1093/Emboj/Cdg354  0.688
2003 Lee I, Harshey RM. The conserved CA/TG motif at Mu termini: T specifies stable transpososome assembly. Journal of Molecular Biology. 330: 261-75. PMID 12823966 DOI: 10.1016/S0022-2836(03)00574-6  0.579
2002 Grainge I, Pathania S, Vologodskii A, Harshey RM, Jayaram M. Symmetric DNA sites are functionally asymmetric within Flp and Cre site-specific DNA recombination synapses. Journal of Molecular Biology. 320: 515-27. PMID 12096907 DOI: 10.1016/S0022-2836(02)00517-X  0.681
2002 Pathania S, Jayaram M, Harshey RM. Path of DNA within the Mu transpososome. Transposase interactions bridging two Mu ends and the enhancer trap five DNA supercoils. Cell. 109: 425-36. PMID 12086600 DOI: 10.1016/S0092-8674(02)00728-6  0.709
2001 Lee I, Harshey RM. Importance of the conserved CA dinucleotide at Mu termini. Journal of Molecular Biology. 314: 433-44. PMID 11846557 DOI: 10.1006/Jmbi.2001.5177  0.558
2001 Mireles JR, Toguchi A, Harshey RM. Salmonella enterica serovar typhimurium swarming mutants with altered biofilm-forming abilities: Surfactin inhibits biofilm formation Journal of Bacteriology. 183: 5848-5854. PMID 11566982 DOI: 10.1128/Jb.183.20.5848-5854.2001  0.319
2001 Jiang H, Harshey RM. The Mu Enhancer Is Functionally Asymmetric Both in cis and in trans. Topological Selectivity of Mu Transposition is Enhancer-independent Journal of Biological Chemistry. 276: 4373-4381. PMID 11084034 DOI: 10.1074/Jbc.M008523200  0.418
2000 Mariconda S, Namgoong SY, Yoon KH, Jiang H, Harshey RM. Domain III function of Mu transposase analysed by directed placement of subunits within the transpososome Journal of Biosciences. 25: 347-360. PMID 11120587 DOI: 10.1007/Bf02703788  0.413
1999 Jiang H, Yang JY, Harshey RM. Criss-crossed interactions between the enhancer and the att sites of phage Mu during DNA transposition Embo Journal. 18: 3845-3855. PMID 10393199 DOI: 10.1093/Emboj/18.13.3845  0.407
1998 Namgoong SY, Sankaralingam S, Harshey RM. Altering the DNA-binding specificity of Mu transposase in vitro Nucleic Acids Research. 26: 3521-3527. PMID 9671813 DOI: 10.1093/Nar/26.15.3521  0.467
1998 Xu CJ, Grainge I, Lee J, Harshey RM, Jayaram M. Unveiling two distinct ribonuclease activities and a topoisomerase activity in a site-specific DNA recombinase Molecular Cell. 1: 729-739. PMID 9660956 DOI: 10.1016/S1097-2765(00)80072-6  0.399
1998 Namgoong SY, Harshey RM. The same two monomers within a MuA tetramer provide the DDE domains for the strand cleavage and strand transfer steps of transposition Embo Journal. 17: 3775-3785. PMID 9649447 DOI: 10.1093/Emboj/17.13.3775  0.48
1998 Burkart M, Toguchi A, Harshey RM. The chemotaxis system, but not chemotaxis, is essential for swarming motility in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 95: 2568-2573. PMID 9482927 DOI: 10.1073/Pnas.95.5.2568  0.305
1998 Namgoong SY, Kim K, Saxena P, Yang JY, Jayaram M, Giedroc DP, Harshey RM. Mutational analysis of domain IIβ of bacteriophage Mu transposase: Domains IIα and IIβ belong to different catalytic complementation groups Journal of Molecular Biology. 275: 221-232. PMID 9466905 DOI: 10.1006/Jmbi.1997.1466  0.312
1996 Sun D, Hurley LH, Harshey RM. Structural distortions induced by integration host factor (IHF) at the H' site of phage lambda probed by (+)-CC-1065, pluramycin, and KMnO4 and by DNA cyclization studies. Biochemistry. 35: 10815-27. PMID 8718873 DOI: 10.1021/Bi952786X  0.451
1996 Wang Z, Namgoong SY, Zhang X, Harshey RM. Kinetic and structural probing of the precleavage synaptic complex (type 0) formed during phage Mu transposition: Action of metal ions and reagents specific to single-stranded DNA Journal of Biological Chemistry. 271: 9619-9626. PMID 8621637 DOI: 10.1074/Jbc.271.16.9619  0.412
1996 Yang JY, Jayaram M, Harshey RM. Positional information within the MU transposase tetramer: Catalytic contributions of individual monomers Cell. 85: 447-455. PMID 8616899 DOI: 10.1016/S0092-8674(00)81122-8  0.427
1995 Kim K, Namgoong SY, Jayaram M, Harshey RM. Step-arrest mutants of Phage Mu transposase: Implications in DNA-protein assembly, Mu end cleavage, and strand transfer Journal of Biological Chemistry. 270: 1472-1479. PMID 7836417 DOI: 10.1074/Jbc.270.3.1472  0.456
1995 Yang JY, Kim K, Jayaram M, Harshey RM. A domain sharing model for active site assembly within the Mu A tetramer during transposition: The enhancer may specify domain contributions Embo Journal. 14: 2374-2384. PMID 7774595 DOI: 10.1002/J.1460-2075.1995.Tb07232.X  0.357
1995 Yang JY, Jayaram M, Harshey RM. Enhancer-independent variants of phage Mu transposase: Enhancer-specific stimulation of catalytic activity by a partner transposase Genes and Development. 9: 2545-2555. PMID 7590234 DOI: 10.1101/Gad.9.20.2545  0.4
1995 Kim K, Harshey RM. Mutational analysis of the att DNA-binding domain of phage Mu transposase Nucleic Acids Research. 23: 3937-3943. PMID 7479039 DOI: 10.1093/Nar/23.19.3937  0.443
1994 Wang Z, Harshey RM. Crucial role for DNA supercoiling in Mu transposition: A kinetic study Proceedings of the National Academy of Sciences of the United States of America. 91: 699-703. PMID 8290584 DOI: 10.1073/Pnas.91.2.699  0.442
1994 Namgoong SY, Jayaram M, Kim K, Harshey RM. DNA-protein cooperativity in the assembly and stabilization of Mu strand transfer complex: Relevance of DNA phasing and att site cleavage Journal of Molecular Biology. 238: 514-527. PMID 8176742 DOI: 10.1006/Jmbi.1994.1311  0.502
1994 Harshey RM. Bees aren't the only ones: Swarming in gram-negative bacteria Molecular Microbiology. 13: 389-394. PMID 7997156 DOI: 10.1111/J.1365-2958.1994.Tb00433.X  0.306
1994 Ding ZM, Harshey RM, Hurley LH. (+)-CC-1065 as a structural probe of mu transposase-induced bending of DNA: Overcoming limitations of hydroxyl-radical footprinting Nucleic Acids Research. 22: 256. DOI: 10.1093/Nar/22.2.256  0.328
1993 Ding ZM, Harshey RM, Hurley LH. (+)-CC-1065 as a structural probe of Mu transposase-induced bending of DNA: overcoming limitations of hydroxyl-radical footprinting. Nucleic Acids Research. 21: 4281-7. PMID 8414983 DOI: 10.1093/nar/21.18.4281  0.364
1992 O'Rear J, Alberti L, Harshey RM. Mutations that impair swarming motility in Serratia marcescens 274 include but are not limited to those affecting chemotaxis or flagellar function Journal of Bacteriology. 174: 6125-6137. PMID 1400161 DOI: 10.1128/Jb.174.19.6125-6137.1992  0.358
1991 Zou A, Leung PC, Harshey RM. Transposase contacts with Mu DNA ends Journal of Biological Chemistry. 266: 20476-20482. PMID 1657926  0.314
1991 Leung PC, Harshey RM. Two mutations of phage Mu transposase that affect strand transfer or interactions with B protein lie in distinct polypeptide domains Journal of Molecular Biology. 219: 189-199. PMID 1645409 DOI: 10.1016/0022-2836(91)90561-J  0.393
1991 Kuo C, Zou A, Jayaram M, Getzoff E, Harshey R. DNA-protein complexes during attachment-site synapsis in Mu DNA transposition. The Embo Journal. 10: 1585-1591. DOI: 10.1002/J.1460-2075.1991.Tb07679.X  0.472
1989 Estepa GR, Harshey RM. Multiple high-frequency transpositions of Tn5 in Serratia marcescens 274 from a thermosensitive replication mutant of plasmid R388 Gene. 81: 355-359. PMID 2553541 DOI: 10.1016/0378-1119(89)90196-0  0.329
1989 Leung PC, Teplow DB, Harshey RM. Interaction of distinct domains in Mu transposase with Mu DNA ends and an internal transpositional enhancer. Nature. 338: 656-8. PMID 2539564 DOI: 10.1038/338656A0  0.449
1988 Jayaram M, Crain KL, Parsons RL, Harshey RM. Holliday junctions in FLP recombination: resolution by step-arrest mutants of FLP protein. Proceedings of the National Academy of Sciences of the United States of America. 85: 7902-6. PMID 3054874 DOI: 10.1073/Pnas.85.21.7902  0.385
1988 Parsons RL, Prasad PV, Harshey RM, Jayaram M. Step-arrest mutants of FLP recombinase: implications for the catalytic mechanism of DNA recombination. Molecular and Cellular Biology. 8: 3303-10. PMID 2974924 DOI: 10.1128/mcb.8.8.3303-3310.1988  0.383
1988 Parsons RL, Harshey R. Autoregulation of phage mu transposase at the level of translation. Nucleic Acids Research. 16: 11285-301. PMID 2849760 DOI: 10.1093/Nar/16.23.11285  0.35
1987 Nakayama C, Teplow DB, Harshey RM. Structural domains in phage Mu transposase: identification of the site-specific DNA-binding domain. Proceedings of the National Academy of Sciences of the United States of America. 84: 1809-13. PMID 3031651 DOI: 10.1073/Pnas.84.7.1809  0.361
1986 Harshey RM, Cuneo SD. Carboxyl-terminal mutants of phage Mu transposase Journal of Genetics. 65: 159-174. DOI: 10.1007/Bf02931149  0.36
1985 Harshey RM, Getzoff ED, Baldwin DL, Miller JL, Chaconas G. Primary structure of phage Mu transposase: Homology to Mu repressor Proceedings of the National Academy of Sciences of the United States of America. 82: 7676-7680. PMID 2999776 DOI: 10.1073/Pnas.82.22.7676  0.451
1984 Miller JL, Anderson SK, Fujita DJ, Chaconas G, Baldwin DL, Harshey RM. The nucleotide sequence of the B gene of bacteriophage Mu Nucleic Acids Research. 12: 8627-8638. PMID 6095204 DOI: 10.1093/Nar/12.22.8627  0.348
1984 Harshey RM. Transposition without duplication of infecting bacteriophage Mu DNA Nature. 311: 580-581. PMID 6090947 DOI: 10.1038/311580A0  0.452
1983 Harshey RM, Bukhari AI. Infecting bacteriophage Mu DNA forms a circular DNA-protein complex Journal of Molecular Biology. 167: 427-441. PMID 6306260 DOI: 10.1016/S0022-2836(83)80343-X  0.469
1983 Harshey RM. Switch in the transposition products of Mu DNA mediated by proteins: Cointegrates versus simple insertions Proceedings of the National Academy of Sciences of the United States of America. 80: 2012-2016. PMID 6300888 DOI: 10.1073/Pnas.80.7.2012  0.429
1982 Harshey RM, McKay R, Bukhari AI. DNA intermediates in transposition of phage Mu Cell. 29: 561-571. PMID 6288263 DOI: 10.1016/0092-8674(82)90172-6  0.465
1981 Harshey RM, Bukhari AI. A mechanism of DNA transposition Proceedings of the National Academy of Sciences of the United States of America. 78: 1090-1094. PMID 6940128 DOI: 10.1073/Pnas.78.2.1090  0.458
1981 Chaconas G, Harshey RM, Sarvetnick N, Bukhari AI. Predominant end-products of prophage Mu DNA transposition during the lytic cycle are replicon fusions Journal of Molecular Biology. 150: 341-359. PMID 6271975 DOI: 10.1016/0022-2836(81)90551-9  0.36
1981 Chaconas G, Harshey RM, Sarvetnick N, Bukhari AI. Mechanism of bacteriophage Mu DNA transposition Cold Spring Harbor Symposia On Quantitative Biology. 45: 311-322. PMID 6271478  0.337
1981 Chaconas G, de Bruijn FJ, Casadaban MJ, Lupski JR, Kwoh TJ, Harshey RM, DuBow MS, Bukhari AI. In vitro and in vivo manipulations of bacteriophage Mu DNA: Cloning of Mu ends and construction of mini-Mu's carrying selectable markers Gene. 13: 37-46. PMID 6263754 DOI: 10.1016/0378-1119(81)90041-X  0.408
1980 Chaconas G, Harshey RM, Bukhari AI. Association of Mu-containing plasmids with the Escherichia coli chromosome upon prophage induction Proceedings of the National Academy of Sciences of the United States of America. 77: 1778-1782. PMID 6246503 DOI: 10.1073/Pnas.77.4.1778  0.472
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