Patricia Brown - Publications

Neuroscience McGill University, Montreal, QC, Canada 
Excitatory and Inhibitory Ligand-Gated Ion Channels

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Brown PMGE, McGuire H, Bowie D. Stargazin and cornichon-3 relieve polyamine block of AMPA receptors by enhancing blocker permeation. The Journal of General Physiology. PMID 29222130 DOI: 10.1085/jgp.201711895  1
2017 Paramo T, Brown PMGE, Musgaard M, Bowie D, Biggin PC. Functional Validation of Heteromeric Kainate Receptor Models. Biophysical Journal. PMID 28935133 DOI: 10.1016/j.bpj.2017.08.047  1
2016 Krogsgaard-Larsen N, Delgar CG, Koch K, Brown PM, Møller C, Han L, Huynh TH, Hansen SW, Nielsen B, Bowie D, Pickering DS, Kastrup JS, Frydenvang K, Bunch L. Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. Journal of Medicinal Chemistry. PMID 28005385 DOI: 10.1021/acs.jmedchem.6b01516  1
2015 Brown PM, Aurousseau MR, Musgaard M, Biggin PC, Bowie D. Kainate receptor pore-forming and auxiliary subunits regulate channel block by a novel mechanism. The Journal of Physiology. PMID 26682513 DOI: 10.1113/JP271690  1
2015 Accardi MV, Brown PM, Miraucourt LS, Orser BA, Bowie D. α6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9676-88. PMID 26134650 DOI: 10.1523/JNEUROSCI.0513-15.2015  1
2015 Demmer CS, Møller C, Brown PM, Han L, Pickering DS, Nielsen B, Bowie D, Frydenvang K, Kastrup JS, Bunch L. Binding Mode of an α-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1. Acs Chemical Neuroscience. 6: 845-54. PMID 25856736 DOI: 10.1021/acschemneuro.5b00038  1
2014 Penna A, Wang DS, Yu J, Lecker I, Brown PM, Bowie D, Orser BA. Hydrogen peroxide increases GABAA receptor-mediated tonic current in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10624-34. PMID 25100596 DOI: 10.1523/JNEUROSCI.0335-14.2014  1
2014 Accardi MV, Daniels BA, Brown PM, Fritschy JM, Tyagarajan SK, Bowie D. Mitochondrial reactive oxygen species regulate the strength of inhibitory GABA-mediated synaptic transmission. Nature Communications. 5: 3168. PMID 24430741 DOI: 10.1038/ncomms4168  1
2011 Lachance-Touchette P, Brown P, Meloche C, Kinirons P, Lapointe L, Lacasse H, Lortie A, Carmant L, Bedford F, Bowie D, Cossette P. Novel α1 and γ2 GABAA receptor subunit mutations in families with idiopathic generalized epilepsy. The European Journal of Neuroscience. 34: 237-49. PMID 21714819 DOI: 10.1111/j.1460-9568.2011.07767.x  1
2009 Fay AM, Corbeil CR, Brown P, Moitessier N, Bowie D. Functional characterization and in silico docking of full and partial GluK2 kainate receptor agonists. Molecular Pharmacology. 75: 1096-107. PMID 19225180 DOI: 10.1124/mol.108.054254  1
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