| Year |
Citation |
Score |
| 2022 |
Cedeno-Rosario L, Honda D, Sunderland AM, Lewandowski MD, Taylor WR, Chadee DN. Phosphorylation of mixed lineage kinase MLK3 by cyclin-dependent kinases CDK1 and CDK2 controls ovarian cancer cell division. The Journal of Biological Chemistry. 102263. PMID 35843311 DOI: 10.1016/j.jbc.2022.102263 |
0.566 |
|
| 2021 |
Kasturirangan S, Mehdi B, Chadee DN. LATS1 Regulates MLK3 subcellular localization and MLK3-mediated invasion in ovarian epithelial cells. Molecular and Cellular Biology. PMID 33875576 DOI: 10.1128/MCB.00078-21 |
0.521 |
|
| 2020 |
Harmych SJ, Kumar J, Bouni ME, Chadee DN. Nicotine inhibits MAPK signaling and spheroid invasion in ovarian cancer cells. Experimental Cell Research. 112167. PMID 32649943 DOI: 10.1016/J.Yexcr.2020.112167 |
0.508 |
|
| 2019 |
Kankanamge D, Tennakoon M, Weerasinghe A, Cedeno-Rosario L, Chadee DN, Karunarathne A. G protein αq exerts expression level-dependent distinct signaling paradigms. Cellular Signalling. 58: 34-43. PMID 30849518 DOI: 10.1016/J.Cellsig.2019.02.006 |
0.425 |
|
| 2017 |
Schroyer AL, Stimes NW, Abi Saab WF, Chadee DN. MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells. Oncogene. PMID 29084209 DOI: 10.1038/Onc.2017.396 |
0.653 |
|
| 2017 |
Blessing NA, Kasturirangan S, Zink EM, Schroyer AL, Chadee DN. Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells. Cellular Signalling. 39: 66-73. PMID 28757353 DOI: 10.1016/J.Cellsig.2017.07.021 |
0.475 |
|
| 2015 |
Goh Q, Dearth CL, Corbett JT, Pierre P, Chadee DN, Pizza FX. Intercellular adhesion molecule-1 expression by skeletal muscle cells augments myogenesis. Experimental Cell Research. 331: 292-308. PMID 25281303 DOI: 10.1016/J.Yexcr.2014.09.032 |
0.331 |
|
| 2014 |
Blessing NA, Brockman AL, Chadee DN. The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3. Molecular and Cellular Biology. 34: 3132-43. PMID 24912674 DOI: 10.1128/Mcb.00296-14 |
0.551 |
|
| 2013 |
Chadee DN. Involvement of mixed lineage kinase 3 in cancer. Canadian Journal of Physiology and Pharmacology. 91: 268-74. PMID 23627838 DOI: 10.1139/Cjpp-2012-0258 |
0.645 |
|
| 2012 |
Abi Saab WF, Brown MS, Chadee DN. MLK4β functions as a negative regulator of MAPK signaling and cell invasion. Oncogenesis. 1: e6. PMID 23552557 DOI: 10.1038/oncsis.2012.6 |
0.64 |
|
| 2012 |
Zhan Y, Abi Saab WF, Modi N, Stewart AM, Liu J, Chadee DN. Mixed lineage kinase 3 is required for matrix metalloproteinase expression and invasion in ovarian cancer cells. Experimental Cell Research. 318: 1641-8. PMID 22652451 DOI: 10.1016/J.Yexcr.2012.05.002 |
0.624 |
|
| 2011 |
Zhan Y, Modi N, Stewart AM, Hieronimus RI, Liu J, Gutmann DH, Chadee DN. Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancer. Oncogene. 30: 781-9. PMID 20890305 DOI: 10.1038/Onc.2010.453 |
0.759 |
|
| 2010 |
Zhan Y, Chadee DN. Inhibition of Cdc42-mediated activation of mixed lineage kinase 3 by the tumor suppressor protein merlin. Small Gtpases. 1: 183-186. PMID 21686274 DOI: 10.4161/Sgtp.1.3.14935 |
0.72 |
|
| 2010 |
Chadee DN, Kyriakis JM. Activation of SAPK/JNKs in vitro. Methods in Molecular Biology (Clifton, N.J.). 661: 59-73. PMID 20811976 DOI: 10.1007/978-1-60761-795-2_3 |
0.621 |
|
| 2009 |
Cole ET, Zhan Y, Abi Saab WF, Korchnak AC, Ashburner BP, Chadee DN. Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide-induced cell death. Biochimica Et Biophysica Acta. 1793: 1811-8. PMID 19782705 DOI: 10.1016/J.Bbamcr.2009.09.014 |
0.636 |
|
| 2009 |
Korchnak AC, Zhan Y, Aguilar MT, Chadee DN. Cytokine-induced activation of mixed lineage kinase 3 requires TRAF2 and TRAF6. Cellular Signalling. 21: 1620-5. PMID 19586614 DOI: 10.1016/J.Cellsig.2009.06.008 |
0.667 |
|
| 2009 |
Kosik A, Bekier ME, Katusin JD, Kaur H, Zhou X, Diakonova M, Chadee DN, Taylor WR. Investigating the role of Aurora kinases in RAS signaling. Journal of Cellular Biochemistry. 106: 33-41. PMID 19009561 DOI: 10.1002/Jcb.21974 |
0.493 |
|
| 2006 |
Chadee DN, Xu D, Hung G, Andalibi A, Lim DJ, Luo Z, Gutmann DH, Kyriakis JM. Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein. Proceedings of the National Academy of Sciences of the United States of America. 103: 4463-8. PMID 16537381 DOI: 10.1073/Pnas.0510651103 |
0.617 |
|
| 2004 |
Chadee DN, Kyriakis JM. A novel role for mixed lineage kinase 3 (MLK3) in B-Raf activation and cell proliferation. Cell Cycle (Georgetown, Tex.). 3: 1227-9. PMID 15467451 DOI: 10.4161/Cc.3.10.1187 |
0.607 |
|
| 2004 |
Chadee DN, Kyriakis JM. MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation. Nature Cell Biology. 6: 770-6. PMID 15258589 DOI: 10.1038/Ncb1152 |
0.621 |
|
| 2004 |
Kyriakis JM, Liu H, Chadee DN. Activation of SAPKs/JNKs and p38s in vitro. Methods in Molecular Biology (Clifton, N.J.). 250: 61-88. PMID 14755080 DOI: 10.1385/1-59259-671-1:61 |
0.367 |
|
| 2003 |
Roelen BA, Cohen OS, Raychowdhury MK, Chadee DN, Zhang Y, Kyriakis JM, Alessandrini AA, Lin HY. Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation. American Journal of Physiology. Cell Physiology. 285: C823-30. PMID 12801888 DOI: 10.1152/Ajpcell.00053.2003 |
0.361 |
|
| 2002 |
Chadee DN, Peltier CP, Davie JR. Histone H1(S)-3 phosphorylation in Ha-ras oncogene-transformed mouse fibroblasts. Oncogene. 21: 8397-403. PMID 12466960 DOI: 10.1038/Sj.Onc.1206029 |
0.492 |
|
| 2002 |
Chadee DN, Yuasa T, Kyriakis JM. Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2. Molecular and Cellular Biology. 22: 737-49. PMID 11784851 |
0.526 |
|
| 1999 |
Davie JR, Samuel SK, Spencer VA, Holth LT, Chadee DN, Peltier CP, Sun JM, Chen HY, Wright JA. Organization of chromatin in cancer cells: role of signalling pathways. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 77: 265-75. PMID 10546890 DOI: 10.1139/Bcb-77-4-265 |
0.488 |
|
| 1999 |
Chadee DN, Hendzel MJ, Tylipski CP, Allis CD, Bazett-Jones DP, Wright JA, Davie JR. Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts. The Journal of Biological Chemistry. 274: 24914-20. PMID 10455166 DOI: 10.1074/Jbc.274.35.24914 |
0.504 |
|
| 1999 |
Davie JR, Sun J, Chen HY, Chadee DN, Hendzel MJ, Tylipski CP, Allis CD, Bazzett-Jones DP, Wright JA. Histone modifications, gene expression, and the nuclear matrix Biochemistry and Cell Biology. 77: 390. DOI: 10.1139/O99-903E |
0.338 |
|
| 1998 |
Davie JR, Chadee DN. Regulation and regulatory parameters of histone modifications. Journal of Cellular Biochemistry. 72: 203-213. PMID 29345837 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<203::Aid-Jcb25>3.0.Co;2-4 |
0.312 |
|
| 1998 |
Holth LT, Chadee DN, Spencer VA, Samuel SK, Safneck JR, Davie JR. Chromatin, nuclear matrix and the cytoskeleton: role of cell structure in neoplastic transformation (review). International Journal of Oncology. 13: 827-37. PMID 9735414 DOI: 10.3892/Ijo.13.4.827 |
0.434 |
|
| 1998 |
Fischer AH, Chadee DN, Wright JA, Gansler TS, Davie JR. Ras-associated nuclear structural change appears functionally significant and independent of the mitotic signaling pathway. Journal of Cellular Biochemistry. 70: 130-40. PMID 9632114 DOI: 10.1002/(Sici)1097-4644(19980701)70:1<130::Aid-Jcb13>3.0.Co;2-T |
0.341 |
|
| 1997 |
Chadee DN, Allis CD, Wright JA, Davie JR. Histone H1b phosphorylation is dependent upon ongoing transcription and replication in normal and ras-transformed mouse fibroblasts. The Journal of Biological Chemistry. 272: 8113-6. PMID 9079620 DOI: 10.1074/Jbc.272.13.8113 |
0.44 |
|
| 1995 |
Taylor WR, Chadee DN, Allis CD, Wright JA, Davie JR. Fibroblasts transformed by combinations of ras, myc and mutant p53 exhibit increased phosphorylation of histone H1 that is independent of metastatic potential. Febs Letters. 377: 51-3. PMID 8543017 DOI: 10.1016/0014-5793(95)01314-8 |
0.389 |
|
| 1995 |
Chadee DN, Taylor WR, Hurta RA, Allis CD, Wright JA, Davie JR. Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinase. The Journal of Biological Chemistry. 270: 20098-105. PMID 7650028 DOI: 10.1074/Jbc.270.34.20098 |
0.509 |
|
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