Bernhard Bettler - Publications

Affiliations: 
Biomedicine University of Basel, Basel, Basel-Stadt, Switzerland 
Area:
Synaptic Transmission
Website:
http://www.pharmazentrum.unibas.ch/bettler.html

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Dinamarca MC, Raveh A, Schneider A, Fritzius T, Früh S, Rem PD, Stawarski M, Lalanne T, Turecek R, Choo M, Besseyrias V, Bildl W, Bentrop D, Staufenbiel M, Gassmann M, ... ... Bettler B, et al. Complex formation of APP with GABA receptors links axonal trafficking to amyloidogenic processing. Nature Communications. 10: 1331. PMID 30902970 DOI: 10.1038/s41467-019-09164-3  0.32
2016 Fritzius T, Turecek R, Seddik R, Kobayashi H, Tiao J, Rem PD, Metz M, Kralikova M, Bouvier M, Gassmann M, Bettler B. KCTD hetero-oligomers confer unique kinetic properties on hippocampal GABAB receptor-induced K+-currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28003345 DOI: 10.1523/JNEUROSCI.2181-16.2016  0.32
2016 Pin JP, Bettler B. Organization and functions of mGlu and GABAB receptor complexes. Nature. 540: 60-68. PMID 27905440 DOI: 10.1038/nature20566  0.8
2016 Zhang J, Tan L, Ren Y, Liang J, Lin R, Feng Q, Zhou J, Hu F, Ren J, Wei C, Yu T, Zhuang Y, Bettler B, Wang F, Luo M. Presynaptic Excitation via GABAB Receptors in Habenula Cholinergic Neurons Regulates Fear Memory Expression. Cell. PMID 27426949 DOI: 10.1016/j.cell.2016.06.026  0.56
2015 Schwenk J, Pérez-Garci E, Schneider A, Kollewe A, Gauthier-Kemper A, Fritzius T, Raveh A, Dinamarca MC, Hanuschkin A, Bildl W, Klingauf J, Gassmann M, Schulte U, Bettler B, Fakler B. Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics. Nature Neuroscience. PMID 26691831 DOI: 10.1038/nn.4198  0.56
2015 Giachino C, Boulay JL, Ivanek R, Alvarado A, Tostado C, Lugert S, Tchorz J, Coban M, Mariani L, Bettler B, Lathia J, Frank S, Pfister S, Kool M, Taylor V. A Tumor Suppressor Function for Notch Signaling in Forebrain Tumor Subtypes. Cancer Cell. 28: 730-42. PMID 26669487 DOI: 10.1016/j.ccell.2015.10.008  0.56
2015 Jacobson LH, Sweeney FF, Kaupmann K, O'Leary OF, Gassmann M, Bettler B, Cryan JF. Differential Roles of GABAB1 Subunit Isoforms on Locomotor Responses to Acute and Repeated Administration of Cocaine. Behavioural Brain Research. PMID 26518330 DOI: 10.1016/j.bbr.2015.10.039  0.56
2015 Harmeier A, Obermueller S, Meyer CA, Revel FG, Buchy D, Chaboz S, Dernick G, Wettstein JG, Iglesias A, Rolink A, Bettler B, Hoener MC. Trace amine-associated receptor 1 activation silences GSK3β signaling of TAAR1 and D2R heteromers. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26372541 DOI: 10.1016/j.euroneuro.2015.08.011  0.56
2015 Vertkin I, Styr B, Slomowitz E, Ofir N, Shapira I, Berner D, Fedorova T, Laviv T, Barak-Broner N, Greitzer-Antes D, Gassmann M, Bettler B, Lotan I, Slutsky I. GABAB receptor deficiency causes failure of neuronal homeostasis in hippocampal networks. Proceedings of the National Academy of Sciences of the United States of America. 112: E3291-9. PMID 26056260 DOI: 10.1073/pnas.1424810112  0.56
2015 Takahashi A, Lee RX, Iwasato T, Itohara S, Arima H, Bettler B, Miczek KA, Koide T. Glutamate input in the dorsal raphe nucleus as a determinant of escalated aggression in male mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6452-63. PMID 25904796 DOI: 10.1523/JNEUROSCI.2450-14.2015  0.56
2015 Cathomas F, Stegen M, Sigrist H, Schmid L, Seifritz E, Gassmann M, Bettler B, Pryce CR. Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABAB receptors associated with mood disorders. Translational Psychiatry. 5: e510. PMID 25689571 DOI: 10.1038/tp.2015.8  0.56
2015 Hanack C, Moroni M, Lima WC, Wende H, Kirchner M, Adelfinger L, Schrenk-Siemens K, Tappe-Theodor A, Wetzel C, Kuich PH, Gassmann M, Roggenkamp D, Bettler B, Lewin GR, Selbach M, et al. GABA blocks pathological but not acute TRPV1 pain signals. Cell. 160: 759-70. PMID 25679765 DOI: 10.1016/j.cell.2015.01.022  0.56
2015 Raveh A, Turecek R, Bettler B. Mechanisms of fast desensitization of GABA(B) receptor-gated currents. Advances in Pharmacology (San Diego, Calif.). 73: 145-65. PMID 25637440 DOI: 10.1016/bs.apha.2014.11.004  0.56
2015 Varani AP, Pedrón VT, Machado LM, Antonelli MC, Bettler B, Balerio GN. Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal. Neuropharmacology. 90: 90-101. PMID 25479464 DOI: 10.1016/j.neuropharm.2014.11.013  0.56
2015 Rajalu M, Fritzius T, Adelfinger L, Jacquier V, Besseyrias V, Gassmann M, Bettler B. Pharmacological characterization of GABAB receptor subtypes assembled with auxiliary KCTD subunits. Neuropharmacology. 88: 145-54. PMID 25196734 DOI: 10.1016/j.neuropharm.2014.08.020  0.56
2014 O'Leary OF, Felice D, Galimberti S, Savignac HM, Bravo JA, Crowley T, El Yacoubi M, Vaugeois JM, Gassmann M, Bettler B, Dinan TG, Cryan JF. GABAB(1) receptor subunit isoforms differentially regulate stress resilience. Proceedings of the National Academy of Sciences of the United States of America. 111: 15232-7. PMID 25288769 DOI: 10.1073/pnas.1404090111  0.56
2014 Martin CB, Gassmann M, Chevarin C, Hamon M, Rudolph U, Bettler B, Lanfumey L, Mongeau R. Effect of genetic and pharmacological blockade of GABA receptors on the 5-HT2C receptor function during stress. Journal of Neurochemistry. 131: 566-72. PMID 25113583 DOI: 10.1111/jnc.12929  0.56
2014 Adelfinger L, Turecek R, Ivankova K, Jensen AA, Moss SJ, Gassmann M, Bettler B. GABAB receptor phosphorylation regulates KCTD12-induced K⁺ current desensitization. Biochemical Pharmacology. 91: 369-79. PMID 25065880 DOI: 10.1016/j.bcp.2014.07.013  0.56
2014 Turecek R, Schwenk J, Fritzius T, Ivankova K, Zolles G, Adelfinger L, Jacquier V, Besseyrias V, Gassmann M, Schulte U, Fakler B, Bettler B. Auxiliary GABAB receptor subunits uncouple G protein βγ subunits from effector channels to induce desensitization. Neuron. 82: 1032-44. PMID 24836506 DOI: 10.1016/j.neuron.2014.04.015  0.56
2014 Varani AP, Pedrón VT, Bettler B, Balerio GN. Involvement of GABAB receptors in biochemical alterations induced by anxiety-related responses to nicotine in mice: genetic and pharmacological approaches. Neuropharmacology. 81: 31-41. PMID 24486711 DOI: 10.1016/j.neuropharm.2014.01.030  0.56
2014 Faroni A, Castelnovo LF, Procacci P, Caffino L, Fumagalli F, Melfi S, Gambarotta G, Bettler B, Wrabetz L, Magnaghi V. Deletion of GABA-B receptor in Schwann cells regulates remak bundles and small nociceptive C-fibers. Glia. 62: 548-65. PMID 24474699 DOI: 10.1002/glia.22625  0.56
2014 Di Giorgio NP, Semaan SJ, Kim J, López PV, Bettler B, Libertun C, Lux-Lantos VA, Kauffman AS. Impaired GABAB receptor signaling dramatically up-regulates Kiss1 expression selectively in nonhypothalamic brain regions of adult but not prepubertal mice. Endocrinology. 155: 1033-44. PMID 24424047 DOI: 10.1210/en.2013-1573  0.56
2014 Giachino C, Barz M, Tchorz JS, Tome M, Gassmann M, Bischofberger J, Bettler B, Taylor V. GABA suppresses neurogenesis in the adult hippocampus through GABAB receptors. Development (Cambridge, England). 141: 83-90. PMID 24284211 DOI: 10.1242/dev.102608  0.56
2013 Ito Y, Banno R, Shibata M, Adachi K, Hagimoto S, Hagiwara D, Ozawa Y, Goto M, Suga H, Sugimura Y, Bettler B, Oiso Y, Arima H. GABA type B receptor signaling in proopiomelanocortin neurons protects against obesity, insulin resistance, and hypothalamic inflammation in male mice on a high-fat diet. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17166-73. PMID 24155320 DOI: 10.1523/JNEUROSCI.0897-13.2013  0.56
2013 Di Giorgio NP, Catalano PN, López PV, González B, Semaan SJ, López GC, Kauffman AS, Rulli SB, Somoza GM, Bettler B, Libertun C, Lux-Lantos VA. Lack of functional GABAB receptors alters Kiss1 , Gnrh1 and Gad1 mRNA expression in the medial basal hypothalamus at postnatal day 4. Neuroendocrinology. 98: 212-23. PMID 24080944 DOI: 10.1159/000355631  0.56
2013 Wedemeyer C, Zorrilla de San Martín J, Ballestero J, Gómez-Casati ME, Torbidoni AV, Fuchs PA, Bettler B, Elgoyhen AB, Katz E. Activation of presynaptic GABA(B(1a,2)) receptors inhibits synaptic transmission at mammalian inhibitory cholinergic olivocochlear-hair cell synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15477-87. PMID 24068816 DOI: 10.1523/JNEUROSCI.2554-13.2013  0.56
2013 Ivankova K, Turecek R, Fritzius T, Seddik R, Prezeau L, Comps-Agrar L, Pin JP, Fakler B, Besseyrias V, Gassmann M, Bettler B. Up-regulation of GABA(B) receptor signaling by constitutive assembly with the K+ channel tetramerization domain-containing protein 12 (KCTD12). The Journal of Biological Chemistry. 288: 24848-56. PMID 23843457 DOI: 10.1074/jbc.M113.476770  0.56
2013 Booker SA, Gross A, Althof D, Shigemoto R, Bettler B, Frotscher M, Hearing M, Wickman K, Watanabe M, Kulik Á, Vida I. Differential GABAB-receptor-mediated effects in perisomatic- and dendrite-targeting parvalbumin interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7961-74. PMID 23637187 DOI: 10.1523/JNEUROSCI.1186-12.2013  0.56
2013 Crivello M, Bonaventura MM, Chamson-Reig A, Arany E, Bettler B, Libertun C, Lux-Lantos V. Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors. American Journal of Physiology. Endocrinology and Metabolism. 304: E1064-76. PMID 23531612 DOI: 10.1152/ajpendo.00569.2012  0.56
2013 Craig MT, Mayne EW, Bettler B, Paulsen O, McBain CJ. Distinct roles of GABAB1a- and GABAB1b-containing GABAB receptors in spontaneous and evoked termination of persistent cortical activity. The Journal of Physiology. 591: 835-43. PMID 23266934 DOI: 10.1113/jphysiol.2012.248088  0.56
2013 Foster JD, Kitchen I, Bettler B, Chen Y. GABAB receptor subtypes differentially modulate synaptic inhibition in the dentate gyrus to enhance granule cell output. British Journal of Pharmacology. 168: 1808-19. PMID 23186302 DOI: 10.1111/bph.12073  0.56
2013 Bonaventura MM, Rodriguez D, Ferreira ML, Crivello M, Repetto EM, Bettler B, Libertun C, Lux-Lantos VA. Sex differences in insulin resistance in GABAB1 knockout mice. Life Sciences. 92: 175-82. PMID 23178152 DOI: 10.1016/j.lfs.2012.11.007  0.56
2013 Dill MT, Tornillo L, Fritzius T, Terracciano L, Semela D, Bettler B, Heim MH, Tchorz JS. Constitutive Notch2 signaling induces hepatic tumors in mice. Hepatology (Baltimore, Md.). 57: 1607-19. PMID 23175466 DOI: 10.1002/hep.26165  0.56
2012 Seddik R, Jungblut SP, Silander OK, Rajalu M, Fritzius T, Besseyrias V, Jacquier V, Fakler B, Gassmann M, Bettler B. Opposite effects of KCTD subunit domains on GABA(B) receptor-mediated desensitization. The Journal of Biological Chemistry. 287: 39869-77. PMID 23035119 DOI: 10.1074/jbc.M112.412767  0.56
2012 Zecharia AY, Yu X, Götz T, Ye Z, Carr DR, Wulff P, Bettler B, Vyssotski AL, Brickley SG, Franks NP, Wisden W. GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13062-75. PMID 22993424 DOI: 10.1523/JNEUROSCI.2931-12.2012  0.56
2012 Yang J, Bücker S, Jungblut B, Böttger T, Cinnamon Y, Tchorz J, Müller M, Bettler B, Harvey R, Sun QY, Schneider A, Braun T. Inhibition of Notch2 by Numb/Numblike controls myocardial compaction in the heart. Cardiovascular Research. 96: 276-85. PMID 22865640 DOI: 10.1093/cvr/cvs250  0.56
2012 Varani AP, Moutinho LM, Bettler B, Balerio GN. Acute behavioural responses to nicotine and nicotine withdrawal syndrome are modified in GABA(B1) knockout mice. Neuropharmacology. 63: 863-72. PMID 22727822 DOI: 10.1016/j.neuropharm.2012.06.006  0.56
2012 Tchorz JS, Tome M, Cloëtta D, Sivasankaran B, Grzmil M, Huber RM, Rutz-Schatzmann F, Kirchhoff F, Schaeren-Wiemers N, Gassmann M, Hemmings BA, Merlo A, Bettler B. Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry. Cell Death & Disease. 3: e325. PMID 22717580 DOI: 10.1038/cddis.2012.65  0.56
2012 Gassmann M, Bettler B. Regulation of neuronal GABA(B) receptor functions by subunit composition. Nature Reviews. Neuroscience. 13: 380-94. PMID 22595784 DOI: 10.1038/nrn3249  0.56
2012 Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF. Early-life stress induces visceral hypersensitivity in mice. Neuroscience Letters. 512: 99-102. PMID 22326388 DOI: 10.1016/j.neulet.2012.01.066  0.56
2012 Tchorz JS, Suply T, Ksiazek I, Giachino C, Cloëtta D, Danzer CP, Doll T, Isken A, Lemaistre M, Taylor V, Bettler B, Kinzel B, Mueller M. A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters. Plos One. 7: e30011. PMID 22253858 DOI: 10.1371/journal.pone.0030011  0.56
2011 Laviv T, Vertkin I, Berdichevsky Y, Fogel H, Riven I, Bettler B, Slesinger PA, Slutsky I. Compartmentalization of the GABAB receptor signaling complex is required for presynaptic inhibition at hippocampal synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 12523-32. PMID 21880914 DOI: 10.1523/JNEUROSCI.1527-11.2011  0.56
2011 Comps-Agrar L, Kniazeff J, Nørskov-Lauritsen L, Maurel D, Gassmann M, Gregor N, Prézeau L, Bettler B, Durroux T, Trinquet E, Pin JP. The oligomeric state sets GABA(B) receptor signalling efficacy. The Embo Journal. 30: 2336-49. PMID 21552208 DOI: 10.1038/emboj.2011.143  0.56
2011 Revel FG, Moreau JL, Gainetdinov RR, Bradaia A, Sotnikova TD, Mory R, Durkin S, Zbinden KG, Norcross R, Meyer CA, Metzler V, Chaboz S, Ozmen L, Trube G, Pouzet B, ... Bettler B, et al. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8485-90. PMID 21525407 DOI: 10.1073/pnas.1103029108  0.56
2011 Metz M, Gassmann M, Fakler B, Schaeren-Wiemers N, Bettler B. Distribution of the auxiliary GABAB receptor subunits KCTD8, 12, 12b, and 16 in the mouse brain. The Journal of Comparative Neurology. 519: 1435-54. PMID 21452234 DOI: 10.1002/cne.22610  0.56
2010 Vienne J, Bettler B, Franken P, Tafti M. Differential effects of GABAB receptor subtypes, {gamma}-hydroxybutyric Acid, and Baclofen on EEG activity and sleep regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14194-204. PMID 20962240 DOI: 10.1523/JNEUROSCI.3145-10.2010  0.56
2010 Maurice P, Daulat AM, Turecek R, Ivankova-Susankova K, Zamponi F, Kamal M, Clement N, Guillaume JL, Bettler B, Galès C, Delagrange P, Jockers R. Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling. The Embo Journal. 29: 3646-59. PMID 20859254 DOI: 10.1038/emboj.2010.236  0.56
2010 Pinard A, Seddik R, Bettler B. GABAB receptors: physiological functions and mechanisms of diversity. Advances in Pharmacology (San Diego, Calif.). 58: 231-55. PMID 20655485 DOI: 10.1016/S1054-3589(10)58010-4  0.56
2010 Guetg N, Abdel Aziz S, Holbro N, Turecek R, Rose T, Seddik R, Gassmann M, Moes S, Jenoe P, Oertner TG, Casanova E, Bettler B. NMDA receptor-dependent GABAB receptor internalization via CaMKII phosphorylation of serine 867 in GABAB1. Proceedings of the National Academy of Sciences of the United States of America. 107: 13924-9. PMID 20643921 DOI: 10.1073/pnas.1000909107  0.56
2010 Schwenk J, Metz M, Zolles G, Turecek R, Fritzius T, Bildl W, Tarusawa E, Kulik A, Unger A, Ivankova K, Seddik R, Tiao JY, Rajalu M, Trojanova J, Rohde V, ... ... Bettler B, et al. Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits. Nature. 465: 231-5. PMID 20400944 DOI: 10.1038/nature08964  0.56
2010 Biermann B, Ivankova-Susankova K, Bradaia A, Abdel Aziz S, Besseyrias V, Kapfhammer JP, Missler M, Gassmann M, Bettler B. The Sushi domains of GABAB receptors function as axonal targeting signals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1385-94. PMID 20107064 DOI: 10.1523/JNEUROSCI.3172-09.2010  0.56
2010 Catalano PN, Di Giorgio N, Bonaventura MM, Bettler B, Libertun C, Lux-Lantos VA. Lack of functional GABA(B) receptors alters GnRH physiology and sexual dimorphic expression of GnRH and GAD-67 in the brain. American Journal of Physiology. Endocrinology and Metabolism. 298: E683-96. PMID 20009027 DOI: 10.1152/ajpendo.00532.2009  0.56
2009 Gangadharan V, Agarwal N, Brugger S, Tegeder I, Bettler B, Kuner R, Kurejova M. Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo. Molecular Pain. 5: 68. PMID 19925671 DOI: 10.1186/1744-8069-5-68  0.56
2009 Bradaia A, Trube G, Stalder H, Norcross RD, Ozmen L, Wettstein JG, Pinard A, Buchy D, Gassmann M, Hoener MC, Bettler B. The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system. Proceedings of the National Academy of Sciences of the United States of America. 106: 20081-6. PMID 19892733 DOI: 10.1073/pnas.0906522106  0.56
2009 Casanova E, Guetg N, Vigot R, Seddik R, Julio-Pieper M, Hyland NP, Cryan JF, Gassmann M, Bettler B. A mouse model for visualization of GABA(B) receptors. Genesis (New York, N.Y. : 2000). 47: 595-602. PMID 19603512 DOI: 10.1002/dvg.20535  0.56
2009 Fernández-Alacid L, Aguado C, Ciruela F, Martín R, Colón J, Cabañero MJ, Gassmann M, Watanabe M, Shigemoto R, Wickman K, Bettler B, Sánchez-Prieto J, Luján R. Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells. Journal of Neurochemistry. 110: 1363-76. PMID 19558451 DOI: 10.1111/j.1471-4159.2009.06229.x  0.56
2009 Tchorz JS, Kinter J, Müller M, Tornillo L, Heim MH, Bettler B. Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice. Hepatology (Baltimore, Md.). 50: 871-9. PMID 19551907 DOI: 10.1002/hep.23048  0.56
2009 Matsuki T, Nomiyama M, Takahira H, Hirashima N, Kunita S, Takahashi S, Yagami K, Kilduff TS, Bettler B, Yanagisawa M, Sakurai T. Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture. Proceedings of the National Academy of Sciences of the United States of America. 106: 4459-64. PMID 19246384 DOI: 10.1073/pnas.0811126106  0.56
2009 Guetg N, Seddik R, Vigot R, Turecek R, Gassmann M, Vogt KE, Bräuner-Osborne H, Shigemoto R, Kretz O, Frotscher M, Kulik A, Bettler B. The GABAB1a isoform mediates heterosynaptic depression at hippocampal mossy fiber synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1414-23. PMID 19193888 DOI: 10.1523/JNEUROSCI.3697-08.2009  0.56
2009 Wellendorph P, Johansen LD, Jensen AA, Casanova E, Gassmann M, Deprez P, Clément-Lacroix P, Bettler B, Bräuner-Osborne H. No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions. Journal of Molecular Endocrinology. 42: 215-23. PMID 19103720 DOI: 10.1677/JME-08-0149  0.56
2009 Maison SF, Casanova E, Holstein GR, Bettler B, Liberman MC. Loss of GABAB receptors in cochlear neurons: threshold elevation suggests modulation of outer hair cell function by type II afferent fibers. Journal of the Association For Research in Otolaryngology : Jaro. 10: 50-63. PMID 18925381 DOI: 10.1007/s10162-008-0138-7  0.56
2009 Matsuki T, Nomiyama M, Takahira H, Hirashima N, Kunita S, Takahashi S, Yagami KI, Kilduff TS, Bettler B, Yanagisawa M, Sakurai T. Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 11, (4459-4464) DOI: 10.1073/pnas.0811126106) Proceedings of the National Academy of Sciences of the United States of America. 106: 8790. DOI: 10.1073/pnas.0903224106  0.56
2008 Tiao JY, Bradaia A, Biermann B, Kaupmann K, Metz M, Haller C, Rolink AG, Pless E, Barlow PN, Gassmann M, Bettler B. The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. The Journal of Biological Chemistry. 283: 31005-11. PMID 18765663 DOI: 10.1074/jbc.M804464200  0.56
2008 Magnaghi V, Ballabio M, Camozzi F, Colleoni M, Consoli A, Gassmann M, Lauria G, Motta M, Procacci P, Trovato AE, Bettler B. Altered peripheral myelination in mice lacking GABAB receptors. Molecular and Cellular Neurosciences. 37: 599-609. PMID 18206390 DOI: 10.1016/j.mcn.2007.12.009  0.56
2008 Lindemann L, Meyer CA, Jeanneau K, Bradaia A, Ozmen L, Bluethmann H, Bettler B, Wettstein JG, Borroni E, Moreau JL, Hoener MC. Trace amine-associated receptor 1 modulates dopaminergic activity. The Journal of Pharmacology and Experimental Therapeutics. 324: 948-56. PMID 18083911 DOI: 10.1124/jpet.107.132647  0.56
2008 Bonaventura MM, Catalano PN, Chamson-Reig A, Arany E, Hill D, Bettler B, Saravia F, Libertun C, Lux-Lantos VA. GABAB receptors and glucose homeostasis: evaluation in GABAB receptor knockout mice. American Journal of Physiology. Endocrinology and Metabolism. 294: E157-67. PMID 17971510 DOI: 10.1152/ajpendo.00615.2006  0.56
2007 Mutel V, Bettler B. The pros of not being competitive. Current Neuropharmacology. 5: 148. PMID 19305796 DOI: 10.2174/157015907781695964  0.56
2007 Ulrich D, Besseyrias V, Bettler B. Functional mapping of GABA(B)-receptor subtypes in the thalamus. Journal of Neurophysiology. 98: 3791-5. PMID 17881477 DOI: 10.1152/jn.00756.2007  0.56
2007 Pinheiro PS, Perrais D, Coussen F, Barhanin J, Bettler B, Mann JR, Malva JO, Heinemann SF, Mulle C. GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses. Proceedings of the National Academy of Sciences of the United States of America. 104: 12181-6. PMID 17620617 DOI: 10.1073/pnas.0608891104  0.56
2007 Cheng Z, Tu C, Rodriguez L, Chen TH, Dvorak MM, Margeta M, Gassmann M, Bettler B, Shoback D, Chang W. Type B gamma-aminobutyric acid receptors modulate the function of the extracellular Ca2+-sensing receptor and cell differentiation in murine growth plate chondrocytes. Endocrinology. 148: 4984-92. PMID 17615148 DOI: 10.1210/en.2007-0653  0.56
2007 Ksiazek I, Burkhardt C, Lin S, Seddik R, Maj M, Bezakova G, Jucker M, Arber S, Caroni P, Sanes JR, Bettler B, Ruegg MA. Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7183-95. PMID 17611272 DOI: 10.1523/JNEUROSCI.1609-07.2007  0.56
2007 Chang W, Tu C, Cheng Z, Rodriguez L, Chen TH, Gassmann M, Bettler B, Margeta M, Jan LY, Shoback D. Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons. The Journal of Biological Chemistry. 282: 25030-40. PMID 17591780 DOI: 10.1074/jbc.M700924200  0.56
2007 Jacobson LH, Kelly PH, Bettler B, Kaupmann K, Cryan JF. Specific roles of GABA(B(1)) receptor isoforms in cognition. Behavioural Brain Research. 181: 158-62. PMID 17498817 DOI: 10.1016/j.bbr.2007.03.033  0.56
2007 Ulrich D, Bettler B. GABA(B) receptors: synaptic functions and mechanisms of diversity. Current Opinion in Neurobiology. 17: 298-303. PMID 17433877 DOI: 10.1016/j.conb.2007.04.001  0.56
2007 Jacobson LH, Bettler B, Kaupmann K, Cryan JF. Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety. Psychopharmacology. 190: 541-53. PMID 17171558 DOI: 10.1007/s00213-006-0631-9  0.56
2006 Jacobson LH, Bettler B, Kaupmann K, Cryan JF. GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice. The Journal of Pharmacology and Experimental Therapeutics. 319: 1317-26. PMID 16990508 DOI: 10.1124/jpet.106.111971  0.56
2006 Jacobson LH, Kelly PH, Bettler B, Kaupmann K, Cryan JF. GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8800-3. PMID 16928868 DOI: 10.1523/JNEUROSCI.2076-06.2006  0.56
2006 Shaban H, Humeau Y, Herry C, Cassasus G, Shigemoto R, Ciocchi S, Barbieri S, van der Putten H, Kaupmann K, Bettler B, Lüthi A. Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition. Nature Neuroscience. 9: 1028-35. PMID 16819521 DOI: 10.1038/nn1732  0.56
2006 Pérez-Garci E, Gassmann M, Bettler B, Larkum ME. The GABAB1b isoform mediates long-lasting inhibition of dendritic Ca2+ spikes in layer 5 somatosensory pyramidal neurons. Neuron. 50: 603-16. PMID 16701210 DOI: 10.1016/j.neuron.2006.04.019  0.56
2006 Vigot R, Barbieri S, Bräuner-Osborne H, Turecek R, Shigemoto R, Zhang YP, Luján R, Jacobson LH, Biermann B, Fritschy JM, Vacher CM, Müller M, Sansig G, Guetg N, Cryan JF, ... ... Bettler B, et al. Differential compartmentalization and distinct functions of GABAB receptor variants. Neuron. 50: 589-601. PMID 16701209 DOI: 10.1016/j.neuron.2006.04.014  0.56
2006 Bettler B, Tiao JY. Molecular diversity, trafficking and subcellular localization of GABAB receptors. Pharmacology & Therapeutics. 110: 533-43. PMID 16644017 DOI: 10.1016/j.pharmthera.2006.03.006  0.56
2006 Kulik A, Vida I, Fukazawa Y, Guetg N, Kasugai Y, Marker CL, Rigato F, Bettler B, Wickman K, Frotscher M, Shigemoto R. Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4289-97. PMID 16624949 DOI: 10.1523/JNEUROSCI.4178-05.2006  0.56
2006 Vacher CM, Gassmann M, Desrayaud S, Challet E, Bradaia A, Hoyer D, Waldmeier P, Kaupmann K, Pévet P, Bettler B. Hyperdopaminergia and altered locomotor activity in GABAB1-deficient mice. Journal of Neurochemistry. 97: 979-91. PMID 16606363 DOI: 10.1111/j.1471-4159.2006.03806.x  0.56
2006 Rey-Roldán EB, Bianchi MS, Bettler B, Becu-Villalobos D, Lux-Lantos VA, Libertun C. Adenohypophyseal and hypothalamic GABA B receptor subunits are downregulated by estradiol in adult female rats. Life Sciences. 79: 342-50. PMID 16516242 DOI: 10.1016/j.lfs.2006.01.014  0.56
2006 Engle MP, Gassman M, Sykes KT, Bettler B, Hammond DL. Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root ganglia of the rat. Neuroscience. 138: 1277-87. PMID 16427742 DOI: 10.1016/j.neuroscience.2005.11.064  0.56
2005 Catalano PN, Bonaventura MM, Silveyra P, Bettler B, Libertun C, Lux-Lantos VA. GABA(B1) knockout mice reveal alterations in prolactin levels, gonadotropic axis, and reproductive function. Neuroendocrinology. 82: 294-305. PMID 16682806 DOI: 10.1159/000093128  0.56
2005 Bianchi MS, Lux-Lantos VA, Bettler B, Libertun C. Expression of gamma-aminobutyric acid B receptor subunits in hypothalamus of male and female developing rats. Brain Research. Developmental Brain Research. 160: 124-9. PMID 16297450 DOI: 10.1016/j.devbrainres.2005.06.017  0.56
2005 Sauter K, Grampp T, Fritschy JM, Kaupmann K, Bettler B, Mohler H, Benke D. Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA(B) receptors. The Journal of Biological Chemistry. 280: 33566-72. PMID 16081421 DOI: 10.1074/jbc.M503482200  0.56
2005 Gassmann M, Haller C, Stoll Y, Abdel Aziz S, Biermann B, Mosbacher J, Kaupmann K, Bettler B. The RXR-type endoplasmic reticulum-retention/retrieval signal of GABAB1 requires distant spacing from the membrane to function. Molecular Pharmacology. 68: 137-44. PMID 15805225 DOI: 10.1124/mol.104.010256  0.56
2005 Mombereau C, Kaupmann K, Gassmann M, Bettler B, van der Putten H, Cryan JF. Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. Neuroreport. 16: 307-10. PMID 15706241 DOI: 10.1097/00001756-200502280-00021  0.56
2005 Deriu D, Gassmann M, Firbank S, Ristig D, Lampert C, Mosbacher J, Froestl W, Kaupmann K, Bettler B, Grütter MG. Determination of the minimal functional ligand-binding domain of the GABAB1b receptor. The Biochemical Journal. 386: 423-31. PMID 15482257 DOI: 10.1042/BJ20040804  0.56
2004 Bianchi MS, Catalano PN, Bonaventura MM, Silveyra P, Bettler B, Libertun C, Lux-Lantos VA. Effect of androgens on sexual differentiation of pituitary gamma-aminobutyric acid receptor subunit GABA(B) expression. Neuroendocrinology. 80: 129-42. PMID 15591793 DOI: 10.1159/000082527  0.56
2004 Tabata T, Araishi K, Hashimoto K, Hashimotodani Y, van der Putten H, Bettler B, Kano M. Ca2+ activity at GABAB receptors constitutively promotes metabotropic glutamate signaling in the absence of GABA. Proceedings of the National Academy of Sciences of the United States of America. 101: 16952-7. PMID 15550547 DOI: 10.1073/pnas.0405387101  0.56
2004 Haller C, Casanova E, Müller M, Vacher CM, Vigot R, Doll T, Barbieri S, Gassmann M, Bettler B. Floxed allele for conditional inactivation of the GABAB(1) gene. Genesis (New York, N.Y. : 2000). 40: 125-30. PMID 15493018 DOI: 10.1002/gene.20073  0.56
2004 Rüttimann E, Vacher CM, Gassmann M, Kaupmann K, Van der Putten H, Bettler B. Altered hippocampal expression of calbindin-D-28k and calretinin in GABA(B(1))-deficient mice. Biochemical Pharmacology. 68: 1613-20. PMID 15451404 DOI: 10.1016/j.bcp.2004.07.019  0.56
2004 Fritschy JM, Sidler C, Parpan F, Gassmann M, Kaupmann K, Bettler B, Benke D. Independent maturation of the GABA(B) receptor subunits GABA(B1) and GABA(B2) during postnatal development in rodent brain. The Journal of Comparative Neurology. 477: 235-52. PMID 15305362 DOI: 10.1002/cne.20188  0.56
2004 Bettler B, Kaupmann K, Mosbacher J, Gassmann M. Molecular structure and physiological functions of GABA(B) receptors. Physiological Reviews. 84: 835-67. PMID 15269338 DOI: 10.1152/physrev.00036.2003  0.56
2004 Gassmann M, Shaban H, Vigot R, Sansig G, Haller C, Barbieri S, Humeau Y, Schuler V, Müller M, Kinzel B, Klebs K, Schmutz M, Froestl W, Heid J, Kelly PH, ... ... Bettler B, et al. Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6086-97. PMID 15240800 DOI: 10.1523/JNEUROSCI.5635-03.2004  0.56
2004 Cryan JF, Kelly PH, Chaperon F, Gentsch C, Mombereau C, Lingenhoehl K, Froestl W, Bettler B, Kaupmann K, Spooren WP. Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines. The Journal of Pharmacology and Experimental Therapeutics. 310: 952-63. PMID 15113848 DOI: 10.1124/jpet.104.066753  0.56
2004 Merlo A, Bettler B. Glioblastomas on the move. Science's Stke : Signal Transduction Knowledge Environment. 2004: pe18. PMID 15100429 DOI: 10.1126/stke.2292004pe18  0.56
2003 Kaupmann K, Cryan JF, Wellendorph P, Mombereau C, Sansig G, Klebs K, Schmutz M, Froestl W, van der Putten H, Mosbacher J, Bräuner-Osborne H, Waldmeier P, Bettler B. Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice. The European Journal of Neuroscience. 18: 2722-30. PMID 14656321 DOI: 10.1111/j.1460-9568.2003.03013.x  0.56
2003 Saghatelyan AK, Snapyan M, Gorissen S, Meigel I, Mosbacher J, Kaupmann K, Bettler B, Kornilov AV, Nifantiev NE, Sakanyan V, Schachner M, Dityatev A. Recognition molecule associated carbohydrate inhibits postsynaptic GABA(B) receptors: a mechanism for homeostatic regulation of GABA release in perisomatic synapses. Molecular and Cellular Neurosciences. 24: 271-82. PMID 14572452 DOI: 10.1016/S1044-7431(03)00163-5  0.56
2003 Vacher CM, Bettler B. GABA(B) receptors as potential therapeutic targets. Current Drug Targets. Cns and Neurological Disorders. 2: 248-59. PMID 12871035  0.56
2003 Furtinger S, Bettler B, Sperk G. Altered expression of GABAB receptors in the hippocampus after kainic-acid-induced seizures in rats. Brain Research. Molecular Brain Research. 113: 107-15. PMID 12750012 DOI: 10.1016/S0169-328X(03)00097-4  0.56
2003 Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Ligands for expression cloning and isolation of GABA(B) receptors. Farmaco (Società Chimica Italiana : 1989). 58: 173-83. PMID 12620413 DOI: 10.1016/S0014-827X(03)00018-1  0.56
2002 Havlickova M, Prezeau L, Duthey B, Bettler B, Pin JP, Blahos J. The intracellular loops of the GB2 subunit are crucial for G-protein coupling of the heteromeric gamma-aminobutyrate B receptor. Molecular Pharmacology. 62: 343-50. PMID 12130687 DOI: 10.1124/mol.62.2.343  0.56
2002 Bowery NG, Bettler B, Froestl W, Gallagher JP, Marshall F, Raiteri M, Bonner TI, Enna SJ. International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function. Pharmacological Reviews. 54: 247-64. PMID 12037141 DOI: 10.1124/pr.54.2.247  0.56
2002 Jensen AA, Mosbacher J, Elg S, Lingenhoehl K, Lohmann T, Johansen TN, Abrahamsen B, Mattsson JP, Lehmann A, Bettler B, Bräuner-Osborne H. The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors. Molecular Pharmacology. 61: 1377-84. PMID 12021399 DOI: 10.1124/mol.61.6.1377  0.56
2002 Kulik A, Nakadate K, Nyíri G, Notomi T, Malitschek B, Bettler B, Shigemoto R. Distinct localization of GABA(B) receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. The European Journal of Neuroscience. 15: 291-307. PMID 11849296 DOI: 10.1046/j.0953-816x.2001.01855.x  0.56
2002 Duthey B, Caudron S, Perroy J, Bettler B, Fagni L, Pin JP, Prézeau L. A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor. The Journal of Biological Chemistry. 277: 3236-41. PMID 11711539 DOI: 10.1074/jbc.M108900200  0.56
2001 Urwyler S, Mosbacher J, Lingenhoehl K, Heid J, Hofstetter K, Froestl W, Bettler B, Kaupmann K. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Molecular Pharmacology. 60: 963-71. PMID 11641424  0.56
2001 Schuler V, Lüscher C, Blanchet C, Klix N, Sansig G, Klebs K, Schmutz M, Heid J, Gentry C, Urban L, Fox A, Spooren W, Jaton AL, Vigouret J, Pozza M, ... ... Bettler B, et al. Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron. 31: 47-58. PMID 11498050 DOI: 10.1016/S0896-6273(01)00345-2  0.56
2001 Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Ligands for expression cloning and isolation of GABA(B) receptors. Farmaco (Società Chimica Italiana : 1989). 56: 101-5. PMID 11347948 DOI: 10.1016/S0014-827X(01)01003-5  0.56
2001 Galvez T, Duthey B, Kniazeff J, Blahos J, Rovelli G, Bettler B, Prézeau L, Pin JP. Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function. The Embo Journal. 20: 2152-9. PMID 11331581 DOI: 10.1093/emboj/20.9.2152  0.56
2001 Gonchar Y, Pang L, Malitschek B, Bettler B, Burkhalter A. Subcellular localization of GABA(B) receptor subunits in rat visual cortex. The Journal of Comparative Neurology. 431: 182-97. PMID 11169999 DOI: 10.1002/1096-9861(20010305)431:2<182::AID-CNE1064>3.0.CO;2-K  0.56
2001 Pagano A, Rovelli G, Mosbacher J, Lohmann T, Duthey B, Stauffer D, Ristig D, Schuler V, Meigel I, Lampert C, Stein T, Prezeau L, Blahos J, Pin J, Froestl W, ... ... Bettler B, et al. C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1189-202. PMID 11160389  0.56
2001 Bianchi M, Rey-Roldán E, Bettler B, Ristig D, Malitschek B, Libertun C, Lux-Lantos V. Ontogenic expression of anterior pituitary GABA(B) receptor subunits. Neuropharmacology. 40: 185-92. PMID 11114397 DOI: 10.1016/S0028-3908(00)00146-5  0.56
2000 Mulle C, Sailer A, Swanson GT, Brana C, O'Gorman S, Bettler B, Heinemann SF. Subunit composition of kainate receptors in hippocampal interneurons. Neuron. 28: 475-84. PMID 11144357  0.56
2000 Towers S, Princivalle A, Billinton A, Edmunds M, Bettler B, Urban L, Castro-Lopes J, Bowery NG. GABAB receptor protein and mRNA distribution in rat spinal cord and dorsal root ganglia. The European Journal of Neuroscience. 12: 3201-10. PMID 10998104 DOI: 10.1046/j.1460-9568.2000.00237.x  0.56
2000 Galvez T, Prezeau L, Milioti G, Franek M, Joly C, Froestl W, Bettler B, Bertrand HO, Blahos J, Pin JP. Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors. The Journal of Biological Chemistry. 275: 41166-74. PMID 10986293 DOI: 10.1074/jbc.M007848200  0.56
2000 Lorente P, Lacampagne A, Pouzeratte Y, Richards S, Malitschek B, Kuhn R, Bettler B, Vassort G. gamma-aminobutyric acid type B receptors are expressed and functional in mammalian cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 97: 8664-9. PMID 10900022 DOI: 10.1073/pnas.97.15.8664  0.56
2000 Galvez T, Urwyler S, Prézeau L, Mosbacher J, Joly C, Malitschek B, Heid J, Brabet I, Froestl W, Bettler B, Kaupmann K, Pin JP. Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: involvement of serine 269 of the GABA(B)R1 subunit. Molecular Pharmacology. 57: 419-26. PMID 10692480  0.56
1999 Lingenhoehl K, Brom R, Heid J, Beck P, Froestl W, Kaupmann K, Bettler B, Mosbacher J. Gamma-hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors. Neuropharmacology. 38: 1667-73. PMID 10587082 DOI: 10.1016/S0028-3908(99)00131-8  0.56
1999 Franek M, Pagano A, Kaupmann K, Bettler B, Pin JP, Blahos J. The heteromeric GABA-B receptor recognizes G-protein alpha subunit C-termini. Neuropharmacology. 38: 1657-66. PMID 10587081 DOI: 10.1016/S0028-3908(99)00135-5  0.56
1999 Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Ligands for the isolation of GABA(B) receptors [corrected] . Neuropharmacology. 38: 1641-6. PMID 10587079 DOI: 10.1016/S0028-3908(99)00134-3  0.56
1999 Keir MJ, Barakat MJ, Dev KK, Bittiger H, Bettler B, Henley JM. Characterisation and partial purification of the GABA(B) receptor from the rat cerebellum using the novel antagonist [3H]CGP 62349. Brain Research. Molecular Brain Research. 71: 279-89. PMID 10521582 DOI: 10.1016/S0169-328X(99)00199-0  0.56
1999 Benke D, Honer M, Michel C, Bettler B, Mohler H. gamma-aminobutyric acid type B receptor splice variant proteins GBR1a and GBR1b are both associated with GBR2 in situ and display differential regional and subcellular distribution. The Journal of Biological Chemistry. 274: 27323-30. PMID 10480953 DOI: 10.1074/jbc.274.38.27323  0.56
1999 Pfaff T, Malitschek B, Kaupmann K, Prézeau L, Pin JP, Bettler B, Karschin A. Alternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptor. The European Journal of Neuroscience. 11: 2874-82. PMID 10457184 DOI: 10.1046/j.1460-9568.1999.00704.x  0.56
1999 Bischoff S, Leonhard S, Reymann N, Schuler V, Shigemoto R, Kaupmann K, Bettler B. Spatial distribution of GABA(B)R1 receptor mRNA and binding sites in the rat brain. The Journal of Comparative Neurology. 412: 1-16. PMID 10440706 DOI: 10.1002/(SICI)1096-9861(19990913)412:1<1::AID-CNE1>3.0.CO;2-D  0.56
1999 Malitschek B, Schweizer C, Keir M, Heid J, Froestl W, Mosbacher J, Kuhn R, Henley J, Joly C, Pin JP, Kaupmann K, Bettler B. The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding. Molecular Pharmacology. 56: 448-54. PMID 10419566  0.56
1999 Mosbacher J, Kaupmann K, Schuler V, Ristig D, Struckmeyer K, Pfaff T, Karschin A, Pozza MF, Bettler B. Processing of GABABR1 in heterologous expression systems. Annals of the New York Academy of Sciences. 868: 689-92. PMID 10414355 DOI: 10.1111/j.1749-6632.1999.tb11347.x  0.56
1999 Sander T, Peters C, Kämmer G, Samochowiec J, Zirra M, Mischke D, Ziegler A, Kaupmann K, Bettler B, Epplen JT, Riess O. Association analysis of exonic variants of the gene encoding the GABAB receptor and idiopathic generalized epilepsy. American Journal of Medical Genetics. 88: 305-10. PMID 10402495 DOI: 10.1002/(SICI)1096-8628(19990820)88:4<305::AID-AJMG5>3.0.CO;2-X  0.56
1999 Galvez T, Parmentier ML, Joly C, Malitschek B, Kaupmann K, Kuhn R, Bittiger H, Froestl W, Bettler B, Pin JP. Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding. The Journal of Biological Chemistry. 274: 13362-9. PMID 10224098 DOI: 10.1074/jbc.274.19.13362  0.56
1999 Marshall FH, Jones KA, Kaupmann K, Bettler B. GABA(B) receptors - The first 7TM heterodimers Trends in Pharmacological Sciences. 20: 396-399. DOI: 10.1016/S0165-6147(99)01383-8  0.56
1998 Peters HC, Kämmer G, Volz A, Kaupmann K, Ziegler A, Bettler B, Epplen JT, Sander T, Riess O. Mapping, genomic structure, and polymorphisms of the human GABABR1 receptor gene: evaluation of its involvement in idiopathic generalized epilepsy. Neurogenetics. 2: 47-54. PMID 9933300 DOI: 10.1007/s100480050051  0.56
1998 Kaupmann K, Malitschek B, Schuler V, Heid J, Froestl W, Beck P, Mosbacher J, Bischoff S, Kulik A, Shigemoto R, Karschin A, Bettler B. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature. 396: 683-7. PMID 9872317 DOI: 10.1038/25360  0.56
1998 Zhang C, Bettler B, Duvoisin RM. Differential localization of GABA(B) receptors in the mouse retina. Neuroreport. 9: 3493-7. PMID 9855305  0.56
1998 Kaupmann K, Schuler V, Mosbacher J, Bischoff S, Bittiger H, Heid J, Froestl W, Leonhard S, Pfaff T, Karschin A, Bettler B. Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 95: 14991-6. PMID 9844003 DOI: 10.1073/pnas.95.25.14991  0.56
1998 Malitschek B, Rüegg D, Heid J, Kaupmann K, Bittiger H, Fröstl W, Bettler B, Kuhn R. Developmental changes of agonist affinity at GABABR1 receptor variants in rat brain. Molecular and Cellular Neurosciences. 12: 56-64. PMID 9770340 DOI: 10.1006/mcne.1998.0698  0.56
1998 Couve A, Filippov AK, Connolly CN, Bettler B, Brown DA, Moss SJ. Intracellular retention of recombinant GABAB receptors. The Journal of Biological Chemistry. 273: 26361-7. PMID 9756866 DOI: 10.1074/jbc.273.41.26361  0.56
1998 Koulen P, Malitschek B, Kuhn R, Bettler B, Wässle H, Brandstätter JH. Presynaptic and postsynaptic localization of GABA(B) receptors in neurons of the rat retina. The European Journal of Neuroscience. 10: 1446-56. PMID 9749799 DOI: 10.1046/j.1460-9568.1998.00156.x  0.56
1998 Bettler B, Kaupmann K, Bowery N. GABAB receptors: drugs meet clones. Current Opinion in Neurobiology. 8: 345-50. PMID 9687348 DOI: 10.1016/S0959-4388(98)80059-7  0.56
1998 Mulle C, Sailer A, Pérez-Otaño I, Dickinson-Anson H, Castillo PE, Bureau I, Maron C, Gage FH, Mann JR, Bettler B, Heinemann SF. Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice. Nature. 392: 601-5. PMID 9580260 DOI: 10.1038/33408  0.56
1998 Kaupmann K, Bettler B. Heteromerization of GABA(B) receptors: A new principle for G protein- coupled receptors. Satellite symposium to the 28(th) annual meeting of the society for neuroscience Los Angeles, CA, November 5-7, 1998 Cns Drug Reviews. 4: 376-379.  0.56
1997 Kaupmann K, Huggel K, Heid J, Flor PJ, Bischoff S, Mickel SJ, McMaster G, Angst C, Bittiger H, Froestl W, Bettler B. Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature. 386: 239-46. PMID 9069281 DOI: 10.1038/386239a0  0.56
1997 Bischoff S, Barhanin J, Bettler B, Mulle C, Heinemann S. Spatial distribution of kainate receptor subunit mRNA in the mouse basal ganglia and ventral mesencephalon. The Journal of Comparative Neurology. 379: 541-62. PMID 9067842 DOI: 10.1002/(SICI)1096-9861(19970324)379:4<541::AID-CNE6>3.0.CO;2-2  0.56
1995 Bettler B, Mulle C. Review: neurotransmitter receptors. II. AMPA and kainate receptors. Neuropharmacology. 34: 123-39. PMID 7542368 DOI: 10.1016/0028-3908(94)00141-E  0.56
1994 Stern-Bach Y, Bettler B, Hartley M, Sheppard PO, O'Hara PJ, Heinemann SF. Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins. Neuron. 13: 1345-57. PMID 7527641 DOI: 10.1016/0896-6273(94)90420-0  0.56
1993 Eubanks JH, Puranam RS, Kleckner NW, Bettler B, Heinemann SF, McNamara JO. The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 90: 178-82. PMID 8419920  0.56
1992 Bettler B, Texido G, Raggini S, Rüegg D, Hofstetter H. Immunoglobulin E-binding site in Fc epsilon receptor (Fc epsilon RII/CD23) identified by homolog-scanning mutagenesis. The Journal of Biological Chemistry. 267: 185-91. PMID 1530929  0.56
1992 Sarfati M, Bettler B, Letellier M, Fournier S, Rubio-Trujillo M, Hofstetter H, Delespesse G. Native and recombinant soluble CD23 fragments with IgE suppressive activity. Immunology. 76: 662-7. PMID 1398755  0.56
1992 Mossalayi MD, Arock M, Delespesse G, Hofstetter H, Bettler B, Dalloul AH, Kilchherr E, Quaaz F, Debré P, Sarfati M. Cytokine effects of CD23 are mediated by an epitope distinct from the IgE binding site. The Embo Journal. 11: 4323-8. PMID 1385115  0.56
1992 Bettler B, Egebjerg J, Sharma G, Pecht G, Hermans-Borgmeyer I, Moll C, Stevens CF, Heinemann S. Cloning of a putative glutamate receptor: a low affinity kainate-binding subunit. Neuron. 8: 257-65. PMID 1371217 DOI: 10.1016/0896-6273(92)90292-L  0.56
1992 Boulter J, Bettler B, Dingledine R, Edgebjerg J, Hartley M, Hermans-Borgmeyer I, Hollmann M, Hume RI, Rogers S, Heinemann S. Molecular biology of the glutamate receptors. Clinical Neuropharmacology. 15: 60A-61A. PMID 1323407  0.56
1991 Egebjerg J, Bettler B, Hermans-Borgmeyer I, Heinemann S. Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA. Nature. 351: 745-8. PMID 1648177 DOI: 10.1038/351745a0  0.56
1990 Bettler B, Boulter J, Hermans-Borgmeyer I, O'Shea-Greenfield A, Deneris ES, Moll C, Borgmeyer U, Hollmann M, Heinemann S. Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development. Neuron. 5: 583-95. PMID 1977421 DOI: 10.1016/0896-6273(90)90213-Y  0.56
1989 Bettler B, Hofstetter H, Rao M, Yokoyama WM, Kilchherr F, Conrad DH. Molecular structure and expression of the murine lymphocyte low-affinity receptor for IgE (Fc epsilon RII). Proceedings of the National Academy of Sciences of the United States of America. 86: 7566-70. PMID 2529542  0.56
1989 Bettler B, Maier R, Rüegg D, Hofstetter H. Binding site for IgE of the human lymphocyte low-affinity Fc epsilon receptor (Fc epsilon RII/CD23) is confined to the domain homologous with animal lectins. Proceedings of the National Academy of Sciences of the United States of America. 86: 7118-22. PMID 2476812  0.56
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