Insuk Lee, Ph.D. - Publications

Affiliations: 
2002 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Molecular Biology

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cha J, Yu J, Cho JW, Hemberg M, Lee I. scHumanNet: a single-cell network analysis platform for the study of cell-type specificity of disease genes. Nucleic Acids Research. PMID 36350625 DOI: 10.1093/nar/gkac1042  0.305
2022 Baek S, Yang S, Lee I. COVID-GWAB: A Web-Based Prediction of COVID-19 Host Genes via Network Boosting of Genome-Wide Association Data. Biomolecules. 12. PMID 36291657 DOI: 10.3390/biom12101446  0.327
2021 Kim CY, Baek S, Cha J, Yang S, Kim E, Marcotte EM, Hart T, Lee I. HumanNet v3: an improved database of human gene networks for disease research. Nucleic Acids Research. PMID 34747468 DOI: 10.1093/nar/gkab1048  0.348
2020 Baek S, Lee I. Single-cell ATAC sequencing analysis: From data preprocessing to hypothesis generation. Computational and Structural Biotechnology Journal. 18: 1429-1439. PMID 32637041 DOI: 10.1016/J.Csbj.2020.06.012  0.386
2020 Lee S, Lee T, Yang S, Lee I. BarleyNet: A Network-Based Functional Omics Analysis Server for Cultivated Barley, L. Frontiers in Plant Science. 11: 98. PMID 32133024 DOI: 10.3389/Fpls.2020.00098  0.437
2020 Shim JE, Lee I. Construction of Functional Protein Networks Using Domain Profile Associations. Methods in Molecular Biology (Clifton, N.J.). 2074: 35-44. PMID 31583628 DOI: 10.1007/978-1-4939-9873-9_3  0.312
2019 Kim E, Bae D, Yang S, Ko G, Lee S, Lee B, Lee I. BiomeNet: A database for construction and analysis of functional interaction networks for any species with a sequenced genome. Bioinformatics (Oxford, England). PMID 31599923 DOI: 10.1093/Bioinformatics/Btz776  0.423
2019 Han H, Lee S, Lee I. NGSEA: Network-Based Gene Set Enrichment Analysis for Interpreting Gene Expression Phenotypes with Functional Gene Sets. Molecules and Cells. PMID 31307154 DOI: 10.14348/Molcells.2019.0065  0.395
2019 Shim JE, Kim JH, Shin J, Lee JE, Lee I. Pathway-specific protein domains are predictive for human diseases. Plos Computational Biology. 15: e1007052. PMID 31075101 DOI: 10.1371/Journal.Pcbi.1007052  0.351
2019 Lee T, Lee S, Yang S, Lee I. MaizeNet: A co-functional network for network-assisted systems genetics in Zea mays. The Plant Journal : For Cell and Molecular Biology. PMID 31006149 DOI: 10.1111/tpj.14341  0.366
2019 Kim H, Joe A, Lee M, Yang S, Ma X, Ronald PC, Lee I. A Genome-Scale Co-Functional Network of Xanthomonas Genes Can Accurately Reconstruct Regulatory Circuits Controlled by Two-Component Signaling Systems. Molecules and Cells. PMID 30759970 DOI: 10.14348/Molcells.2018.0403  0.463
2019 Han H, Lehner B, Lee I. Cancer Gene Discovery by Network Analysis of Somatic Mutations Using the MUFFINN Server. Methods in Molecular Biology (Clifton, N.J.). 1907: 37-50. PMID 30542989 DOI: 10.1007/978-1-4939-8967-6_3  0.378
2018 Hwang S, Kim CY, Yang S, Kim E, Hart T, Marcotte EM, Lee I. HumanNet v2: human gene networks for disease research. Nucleic Acids Research. PMID 30418591 DOI: 10.1093/Nar/Gky1126  0.44
2018 Kim CY, Lee M, Lee K, Yoon SS, Lee I. Network-based genetic investigation of virulence-associated phenotypes in methicillin-resistant Staphylococcus aureus. Scientific Reports. 8: 10796. PMID 30018396 DOI: 10.1038/S41598-018-29120-3  0.381
2018 Lee T, Lee I. araGWAB: Network-based boosting of genome-wide association studies in Arabidopsis thaliana. Scientific Reports. 8: 2925. PMID 29440686 DOI: 10.1038/s41598-018-21301-4  0.308
2017 Shim JE, Lee T, Lee I. From sequencing data to gene functions: co-functional network approaches. Animal Cells and Systems. 21: 77-83. PMID 30460054 DOI: 10.1080/19768354.2017.1284156  0.469
2017 Han H, Cho JW, Lee S, Yun A, Kim H, Bae D, Yang S, Kim CY, Lee M, Kim E, Lee S, Kang B, Jeong D, Kim Y, Jeon HN, ... ... Lee I, et al. TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions. Nucleic Acids Research. PMID 29087512 DOI: 10.1093/Nar/Gkx1013  0.305
2017 Lee T, Lee I. AraNet: A Network Biology Server for Arabidopsis thaliana and Other Non-Model Plant Species. Methods in Molecular Biology (Clifton, N.J.). 1629: 225-238. PMID 28623589 DOI: 10.1007/978-1-4939-7125-1_15  0.451
2017 Kim E, Lee I. Network-Based Gene Function Prediction in Mouse and Other Model Vertebrates Using MouseNet Server. Methods in Molecular Biology (Clifton, N.J.). 1611: 183-198. PMID 28451980 DOI: 10.1007/978-1-4939-7015-5_14  0.363
2017 Lee T, Hwang S, Kim CY, Shim H, Kim H, Ronald PC, Marcotte EM, Lee I. WheatNet: A genome-scale functional network for hexaploid bread wheat, Triticum aestivum. Molecular Plant. PMID 28450181 DOI: 10.1016/J.Molp.2017.04.006  0.387
2017 Shim JE, Bang C, Yang S, Lee T, Hwang S, Kim CY, Singh-Blom UM, Marcotte EM, Lee I. GWAB: a web server for the network-based boosting of human genome-wide association data. Nucleic Acids Research. PMID 28449091 DOI: 10.1093/Nar/Gkx284  0.417
2017 Jang K, Kim K, Cho A, Lee I, Choi JK. Network perturbation by recurrent regulatory variants in cancer. Plos Computational Biology. 13: e1005449. PMID 28333928 DOI: 10.1371/Journal.Pcbi.1005449  0.388
2017 Shin J, Lee I. Construction of Functional Gene Networks Using Phylogenetic Profiles. Methods in Molecular Biology (Clifton, N.J.). 1526: 87-98. PMID 27896737 DOI: 10.1007/978-1-4939-6613-4_5  0.407
2017 Kim CY, Lee I. Functional gene networks based on the gene neighborhood in metagenomes Animal Cells and Systems. 21: 301-306. DOI: 10.1080/19768354.2017.1382388  0.485
2016 Shim H, Kim JH, Kim CY, Hwang S, Kim H, Yang S, Lee JE, Lee I. Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource. Nucleic Acids Research. 44: 9611-9623. PMID 27903883 DOI: 10.1093/nar/gkw897  0.337
2016 Yang S, Kim CY, Hwang S, Kim E, Kim H, Shim H, Lee I. COEXPEDIA: exploring biomedical hypotheses via co-expressions associated with medical subject headings (MeSH). Nucleic Acids Research. PMID 27679477 DOI: 10.1093/Nar/Gkw868  0.331
2016 Kim E, Hwang S, Lee I. SoyNet: a database of co-functional networks for soybean Glycine max. Nucleic Acids Research. PMID 27492285 DOI: 10.1093/Nar/Gkw704  0.457
2016 Cho A, Shim JE, Kim E, Supek F, Lehner B, Lee I. MUFFINN: cancer gene discovery via network analysis of somatic mutation data. Genome Biology. 17: 129. PMID 27333808 DOI: 10.1186/S13059-016-0989-X  0.368
2016 Shim JE, Lee I. Weighted mutual information analysis substantially improves domain-based functional network models. Bioinformatics (Oxford, England). PMID 27207946 DOI: 10.1093/Bioinformatics/Btw320  0.338
2016 Hwang S, Kim CY, Ji SG, Go J, Kim H, Yang S, Kim HJ, Cho A, Yoon SS, Lee I. Network-assisted investigation of virulence and antibiotic-resistance systems in Pseudomonas aeruginosa. Scientific Reports. 6: 26223. PMID 27194047 DOI: 10.1038/Srep26223  0.38
2016 Kim SM, Kim JW, Kwak TH, Park SW, Kim KP, Park H, Lim KT, Kang K, Kim J, Yang JH, Han H, Lee I, Hyun JK, Bae YM, Schöler HR, et al. Generation of Integration-free Induced Neural Stem Cells from Mouse Fibroblasts. The Journal of Biological Chemistry. PMID 27189941 DOI: 10.1074/Jbc.M115.713578  0.318
2015 Hwang S, Kim E, Lee I, Marcotte EM. Systematic comparison of variant calling pipelines using gold standard personal exome variants. Scientific Reports. 5: 17875. PMID 26639839 DOI: 10.1038/Srep17875  0.337
2015 Kim E, Hwang S, Kim H, Shim H, Kang B, Yang S, Shim JH, Shin SY, Marcotte EM, Lee I. MouseNet v2: a database of gene networks for studying the laboratory mouse and eight other model vertebrates. Nucleic Acids Research. PMID 26527726 DOI: 10.1093/Nar/Gkv1155  0.478
2015 Shin J, Lee I. Co-Inheritance Analysis within the Domains of Life Substantially Improves Network Inference by Phylogenetic Profiling. Plos One. 10: e0139006. PMID 26394049 DOI: 10.1371/Journal.Pone.0139006  0.405
2015 Shim JE, Hwang S, Lee I. Pathway-Dependent Effectiveness of Network Algorithms for Gene Prioritization. Plos One. 10: e0130589. PMID 26091506 DOI: 10.1371/Journal.Pone.0130589  0.408
2015 Shin J, Yang S, Kim E, Kim CY, Shim H, Cho A, Kim H, Hwang S, Shim JE, Lee I. FlyNet: a versatile network prioritization server for the Drosophila community. Nucleic Acids Research. 43: W91-7. PMID 25943544 DOI: 10.1093/Nar/Gkv453  0.457
2015 Lee I, Mockler TC. Editorial overview: genome studies and molecular genetics: data-driven approaches to genotype-to-phenotype studies in crops. Current Opinion in Plant Biology. 24: iv-vi. PMID 25817324 DOI: 10.1016/J.Pbi.2015.03.001  0.307
2015 Lee T, Oh T, Yang S, Shin J, Hwang S, Kim CY, Kim H, Shim H, Shim JE, Ronald PC, Lee I. RiceNet v2: an improved network prioritization server for rice genes. Nucleic Acids Research. 43: W122-7. PMID 25813048 DOI: 10.1093/nar/gkv253  0.351
2015 Kim H, Jung KW, Maeng S, Chen YL, Shin J, Shim JE, Hwang S, Janbon G, Kim T, Heitman J, Bahn YS, Lee I. Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans. Scientific Reports. 5: 8767. PMID 25739925 DOI: 10.1038/Srep08767  0.421
2015 Lee T, Kim H, Lee I. Network-assisted crop systems genetics: network inference and integrative analysis. Current Opinion in Plant Biology. 24: 61-70. PMID 25698380 DOI: 10.1016/j.pbi.2015.02.001  0.339
2015 Kim T, Dreher K, Nilo-Poyanco R, Lee I, Fiehn O, Lange BM, Nikolau BJ, Sumner L, Welti R, Wurtele ES, Rhee SY. Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis using a genome-scale metabolic network. Plant Physiology. 167: 1685-98. PMID 25670818 DOI: 10.1104/Pp.114.252361  0.386
2015 Kim H, Shim JE, Shin J, Lee I. EcoliNet: a database of cofunctional gene network for Escherichia coli. Database : the Journal of Biological Databases and Curation. 2015. PMID 25650278 DOI: 10.1093/Database/Bav001  0.467
2015 Lee T, Yang S, Kim E, Ko Y, Hwang S, Shin J, Shim JE, Shim H, Kim H, Kim C, Lee I. AraNet v2: an improved database of co-functional gene networks for the study of Arabidopsis thaliana and 27 other nonmodel plant species. Nucleic Acids Research. 43: D996-1002. PMID 25355510 DOI: 10.1093/Nar/Gku1053  0.462
2015 Shim JE, Lee I. Network-assisted approaches for human disease research Animal Cells and Systems. 19: 231-235. DOI: 10.1080/19768354.2015.1074108  0.372
2014 Cho A, Shin J, Hwang S, Kim C, Shim H, Kim H, Kim H, Lee I. WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans. Nucleic Acids Research. 42: W76-82. PMID 24813450 DOI: 10.1093/Nar/Gku367  0.465
2014 Shin J, Lee T, Kim H, Lee I. Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. Molecular Biosystems. 10: 24-9. PMID 24194096 DOI: 10.1039/C3Mb70366E  0.352
2014 Kim H, Shin J, Kim E, Kim H, Hwang S, Shim JE, Lee I. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae. Nucleic Acids Research. 42: D731-6. PMID 24165882 DOI: 10.1093/nar/gkt981  0.373
2013 Kim E, Kim H, Lee I. JiffyNet: a web-based instant protein network modeler for newly sequenced species. Nucleic Acids Research. 41: W192-7. PMID 23685435 DOI: 10.1093/Nar/Gkt419  0.426
2013 Lee I. Network approaches to the genetic dissection of phenotypes in animals and humans Animal Cells and Systems. 17: 75-79. DOI: 10.1080/19768354.2013.789076  0.348
2012 Wang PI, Hwang S, Kincaid RP, Sullivan CS, Lee I, Marcotte EM. RIDDLE: reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network. Genome Biology. 13: R125. PMID 23268829 DOI: 10.1186/Gb-2012-13-12-R125  0.319
2012 Quanbeck SM, Brachova L, Campbell AA, Guan X, Perera A, He K, Rhee SY, Bais P, Dickerson JA, Dixon P, Wohlgemuth G, Fiehn O, Barkan L, Lange I, Lange BM, ... Lee I, et al. Metabolomics as a Hypothesis-Generating Functional Genomics Tool for the Annotation of Arabidopsis thaliana Genes of "Unknown Function". Frontiers in Plant Science. 3: 15. PMID 22645570 DOI: 10.3389/Fpls.2012.00015  0.423
2011 Lee I, Seo YS, Coltrane D, Hwang S, Oh T, Marcotte EM, Ronald PC. Genetic dissection of the biotic stress response using a genome-scale gene network for rice. Proceedings of the National Academy of Sciences of the United States of America. 108: 18548-53. PMID 22042862 DOI: 10.1073/Pnas.1110384108  0.365
2011 Hwang S, Rhee SY, Marcotte EM, Lee I. Systematic prediction of gene function in Arabidopsis thaliana using a probabilistic functional gene network. Nature Protocols. 6: 1429-42. PMID 21886106 DOI: 10.1038/Nprot.2011.372  0.315
2011 Lee I, Blom UM, Wang PI, Shim JE, Marcotte EM. Prioritizing candidate disease genes by network-based boosting of genome-wide association data. Genome Research. 21: 1109-21. PMID 21536720 DOI: 10.1101/Gr.118992.110  0.362
2011 Lee I. Probabilistic functional gene societies. Progress in Biophysics and Molecular Biology. 106: 435-42. PMID 21281658 DOI: 10.1016/J.Pbiomolbio.2011.01.003  0.447
2010 Huang N, Lee I, Marcotte EM, Hurles ME. Characterising and predicting haploinsufficiency in the human genome. Plos Genetics. 6: e1001154. PMID 20976243 DOI: 10.1371/Journal.Pgen.1001154  0.437
2010 Lee I, Lehner B, Vavouri T, Shin J, Fraser AG, Marcotte EM. Predicting genetic modifier loci using functional gene networks. Genome Research. 20: 1143-53. PMID 20538624 DOI: 10.1101/Gr.102749.109  0.435
2010 Lee I, Ambaru B, Thakkar P, Marcotte EM, Rhee SY. Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana. Nature Biotechnology. 28: 149-56. PMID 20118918 DOI: 10.1038/Nbt.1603  0.439
2009 Li Z, Lee I, Moradi E, Hung NJ, Johnson AW, Marcotte EM. Rational extension of the ribosome biogenesis pathway using network-guided genetics. Plos Biology. 7: e1000213. PMID 19806183 DOI: 10.1371/Journal.Pbio.1000213  0.422
2009 Lee I, Marcotte EM. Effects of functional bias on supervised learning of a gene network model. Methods in Molecular Biology (Clifton, N.J.). 541: 463-75. PMID 19381535 DOI: 10.1007/978-1-59745-243-4_20  0.41
2008 Lee I, Marcotte EM. Integrating functional genomics data. Methods in Molecular Biology (Clifton, N.J.). 453: 267-78. PMID 18712309 DOI: 10.1007/978-1-60327-429-6_14  0.374
2008 Lehner B, Lee I. Network-guided genetic screening: building, testing and using gene networks to predict gene function. Briefings in Functional Genomics & Proteomics. 7: 217-27. PMID 18445637 DOI: 10.1093/Bfgp/Eln020  0.452
2008 Lee I, Lehner B, Crombie C, Wong W, Fraser AG, Marcotte EM. A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans. Nature Genetics. 40: 181-8. PMID 18223650 DOI: 10.1038/Ng.2007.70  0.443
2007 McGary KL, Lee I, Marcotte EM. Broad network-based predictability of Saccharomyces cerevisiae gene loss-of-function phenotypes. Genome Biology. 8: R258. PMID 18053250 DOI: 10.1186/Gb-2007-8-12-R258  0.447
2007 Lee I, Li Z, Marcotte EM. An improved, bias-reduced probabilistic functional gene network of baker's yeast, Saccharomyces cerevisiae. Plos One. 2: e988. PMID 17912365 DOI: 10.1371/Journal.Pone.0000988  0.461
2007 Hart GT, Lee I, Marcotte ER. A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality. Bmc Bioinformatics. 8: 236. PMID 17605818 DOI: 10.1186/1471-2105-8-236  0.302
2004 Lee I, Date SV, Adai AT, Marcotte EM. A probabilistic functional network of yeast genes. Science (New York, N.Y.). 306: 1555-8. PMID 15567862 DOI: 10.1126/Science.1099511  0.462
2004 Bork P, Jensen LJ, von Mering C, Ramani AK, Lee I, Marcotte EM. Protein interaction networks from yeast to human. Current Opinion in Structural Biology. 14: 292-9. PMID 15193308 DOI: 10.1016/J.Sbi.2004.05.003  0.359
2003 Lee I, Harshey RM. Patterns of sequence conservation at termini of long terminal repeat (LTR) retrotransposons and DNA transposons in the human genome: lessons from phage Mu. Nucleic Acids Research. 31: 4531-40. PMID 12888514 DOI: 10.1093/Nar/Gkg499  0.566
2003 Lee I, Harshey RM. The conserved CA/TG motif at Mu termini: T specifies stable transpososome assembly. Journal of Molecular Biology. 330: 261-75. PMID 12823966 DOI: 10.1016/S0022-2836(03)00574-6  0.553
2001 Lee I, Harshey RM. Importance of the conserved CA dinucleotide at Mu termini. Journal of Molecular Biology. 314: 433-44. PMID 11846557 DOI: 10.1006/Jmbi.2001.5177  0.548
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