Paul Cumming - Publications

Affiliations: 
Biological Psychiatry Ludwig Maximilians University, München, Bayern, Germany 
Area:
Dopamine, Imaging

211 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lu J, Bao W, Li M, Li L, Zhang Z, Alberts I, Brendel M, Cumming P, Lu H, Xiao Z, Zuo C, Guan Y, Zhao Q, Rominger A. Associations of [F]-APN-1607 Tau PET Binding in the Brain of Alzheimer's Disease Patients With Cognition and Glucose Metabolism. Frontiers in Neuroscience. 14: 604. PMID 32694971 DOI: 10.3389/Fnins.2020.00604  0.382
2020 Han X, Wu P, Alberts I, Zhou H, Yu H, Bargiotas P, Yakushev I, Wang J, Höglinger G, Förster S, Bassetti C, Oertel W, Schwaiger M, Huang SC, Cumming P, et al. Characterizing the heterogeneous metabolic progression in idiopathic REM sleep behavior disorder. Neuroimage. Clinical. 27: 102294. PMID 32570206 DOI: 10.1016/J.Nicl.2020.102294  0.307
2020 Sacher C, Blume T, Beyer L, Biechele G, Sauerbeck J, Eckenweber F, Deussing M, Focke C, Parhizkar S, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Baumann K, Tahirovic S, Kleinberger G, ... ... Cumming P, et al. Asymmetry of fibrillar plaque burden in amyloid mouse models. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32414948 DOI: 10.2967/Jnumed.120.242750  0.314
2020 Weidenauer A, Bauer M, Sauerzopf U, Bartova L, Nics L, Pfaff S, Philippe C, Berroterán-Infante N, Pichler V, Meyer BM, Rabl U, Sezen P, Cumming P, Stimpfl T, Sitte HH, et al. On the relationship of first-episode psychosis to the amphetamine-sensitized state: a dopamine D receptor agonist radioligand study. Translational Psychiatry. 10: 2. PMID 32066718 DOI: 10.1038/S41398-019-0681-5  0.366
2020 Beyer L, Brendel M, Scheiwein F, Sauerbeck J, Hosakawa C, Alberts I, Shi K, Bartenstein P, Ishii K, Seibyl J, Cumming P, Rominger A. Improved Risk Stratification for Progression from Mild Cognitive Impairment to Alzheimer's Disease with a Multi-Analytical Evaluation of Amyloid-β Positron Emission Tomography. Journal of Alzheimer's Disease : Jad. PMID 31985461 DOI: 10.3233/Jad-190818  0.31
2019 Huber M, Beyer L, Prix C, Schönecker S, Palleis C, Rauchmann BS, Morbelli S, Chincarini A, Bruffaerts R, Vandenberghe R, Van Laere K, Kramberger MG, Trost M, Grmek M, Garibotto V, ... Cumming P, et al. Metabolic correlates of dopaminergic loss in dementia with lewy bodies. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31840326 DOI: 10.1002/Mds.27945  0.405
2019 Cumming P, Marton J, Lilius TO, Olberg DE, Rominger A. A Survey of Molecular Imaging of Opioid Receptors. Molecules (Basel, Switzerland). 24. PMID 31752279 DOI: 10.3390/Molecules24224190  0.336
2019 Brendel M, Deussing M, Blume T, Kaiser L, Probst F, Overhoff F, Peters F, von Ungern-Sternberg B, Ryazanov S, Leonov A, Griesinger C, Zwergal A, Levin J, Bartenstein P, Yakushev I, ... Cumming P, et al. Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau. Alzheimer's Research & Therapy. 11: 67. PMID 31370885 DOI: 10.1186/S13195-019-0522-Z  0.338
2019 Kim JH, Choe YS, Cumming P, Son YD, Kim HK, Joo YH, Kim JH. Relationship of self-transcendence traits with in vivo dopamine D2/3 receptor availability and functional connectivity: an [ F]fallypride PET and fMRI study. Synapse (New York, N.Y.). PMID 31206840 DOI: 10.1002/Syn.22121  0.359
2019 Gründer G, Cumming P. The downside of downregulation. Brain : a Journal of Neurology. 142: 1500-1502. PMID 31135045 DOI: 10.1093/Brain/Awz133  0.315
2018 Narayanaswami V, Dahl K, Bernard-Gauthier V, Josephson L, Cumming P, Vasdev N. Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO. Molecular Imaging. 17: 1536012118792317. PMID 30203712 DOI: 10.1177/1536012118792317  0.349
2018 Kim JH, Cumming P, Son YD, Kim HK, Joo YH, Kim JH. Altered connectivity between striatal and extrastriatal regions in patients with schizophrenia on maintenance antipsychotics: an [ F]fallypride PET and functional MRI study. Synapse (New York, N.Y.). PMID 30063263 DOI: 10.1002/Syn.22064  0.375
2018 Amato D, Canneva F, Cumming P, Maschauer S, Groos D, Dahlmanns JK, Grömer TW, Chiofalo L, Dahlmanns M, Zheng F, Kornhuber J, Prante O, Alzheimer C, von Hörsten S, Müller CP. A dopaminergic mechanism of antipsychotic drug efficacy, failure, and failure reversal: the role of the dopamine transporter. Molecular Psychiatry. PMID 30038229 DOI: 10.1038/S41380-018-0114-5  0.321
2018 Veselinović T, Vernaleken I, Janouschek H, Cumming P, Paulzen M, Mottaghy FM, Gründer G. The role of striatal dopamine D receptors in cognitive performance in drug-free patients with schizophrenia. Psychopharmacology. PMID 29717334 DOI: 10.1007/S00213-018-4916-6  0.324
2017 Cumming P, Burgher B, Patkar O, Breakspear M, Vasdev N, Thomas P, Liu GJ, Banati R. Sifting through the surfeit of neuroinflammation tracers. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17748786. PMID 29256293 DOI: 10.1177/0271678X17748786  0.403
2017 Kanthan M, Cumming P, Hooker JM, Vasdev N. Classics in Neuroimaging: Imaging the Dopaminergic Pathway with PET. Acs Chemical Neuroscience. PMID 28719177 DOI: 10.1021/Acschemneuro.7B00252  0.401
2016 Cumming P, Gallinat J. Invited commentary: mapping the alteration in glutamate with GluCEST MRI in a mouse model of dopamine deficiency: An Editorial Highlight for 'Mapping the alterations in glutamate with GluCEST MRI in a mouse model of dopamine deficiency'. Journal of Neurochemistry. PMID 27747879 DOI: 10.1111/Jnc.13759  0.304
2016 Deutschländer A, la Fougère C, Boetzel K, Albert NL, Gildehaus FJ, Bartenstein P, Xiong G, Cumming P. Occupancy of pramipexole (Sifrol) at cerebral dopamine D2/3 receptors in Parkinson's disease patients. Neuroimage. Clinical. 12: 41-6. PMID 27408789 DOI: 10.1016/J.Nicl.2016.06.007  0.426
2016 Olberg DE, Bauer N, Andressen KW, Hjørnevik T, Cumming P, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL. Brain penetrant small molecule (18)F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats. Nuclear Medicine and Biology. 43: 478-489. PMID 27236283 DOI: 10.1016/J.Nucmedbio.2016.05.003  0.381
2016 Cumming P, Gryglewski G, Kranz GS, Lanzenberger R. Commentary: The serotonin transporter in depression: Meta-analysis of in vivo and post mortem findings and implications for understanding and treating depression. Journal of Affective Disorders. 199: 21-22. PMID 27057649 DOI: 10.1016/J.Jad.2016.03.058  0.322
2015 Rademacher L, Prinz S, Winz O, Henkel K, Dietrich CA, Schmaljohann J, Mohammadkhani Shali S, Schabram I, Stoppe C, Cumming P, Hilgers RD, Kumakura Y, Coburn M, Mottaghy FM, Gründer G, et al. Effects of Smoking Cessation on Presynaptic Dopamine Function of Addicted Male Smokers. Biological Psychiatry. PMID 26803340 DOI: 10.1016/J.Biopsych.2015.11.009  0.331
2015 Schlüter T, Winz O, Henkel K, Eggermann T, Mohammadkhani-Shali S, Dietrich C, Heinzel A, Decker M, Cumming P, Zerres K, Piel M, Mottaghy FM, Vernaleken I. MAOA-VNTR polymorphism modulates context-dependent dopamine release and aggressive behavior in males. Neuroimage. 125: 378-385. PMID 26481676 DOI: 10.1016/J.Neuroimage.2015.10.031  0.347
2015 Maschauer S, Haller A, Riss PJ, Kuwert T, Prante O, Cumming P. Specific binding of [(18) F]fluoroethyl-harmol to monoamine oxidase A in rat brain cryostat sections, and compartmental analysis of binding in living brain. Journal of Neurochemistry. PMID 26386360 DOI: 10.1111/Jnc.13370  0.435
2015 Brendel M, Jaworska A, Grießinger E, Rötzer C, Burgold S, Gildehaus FJ, Carlsen J, Cumming P, Baumann K, Haass C, Steiner H, Bartenstein P, Herms J, Rominger A. Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models. Plos One. 10: e0116678. PMID 25706990 DOI: 10.1371/Journal.Pone.0116678  0.317
2015 Vafaee MS, Gjedde A, Imamirad N, Vang K, Chakravarty MM, Lerch JP, Cumming P. Smoking normalizes cerebral blood flow and oxygen consumption after 12-hour abstention. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 699-705. PMID 25605288 DOI: 10.1038/Jcbfm.2014.246  0.305
2015 Deserno L, Beck A, Huys QJ, Lorenz RC, Buchert R, Buchholz HG, Plotkin M, Kumakara Y, Cumming P, Heinze HJ, Grace AA, Rapp MA, Schlagenhauf F, Heinz A. Chronic alcohol intake abolishes the relationship between dopamine synthesis capacity and learning signals in the ventral striatum. The European Journal of Neuroscience. 41: 477-86. PMID 25546072 DOI: 10.1111/Ejn.12802  0.317
2015 Cumming P, Maschauer S, Riss PJ, Grill E, Pischetsrieder M, Kuwert T, Prante O. Perturbed Development of Striatal Dopamine Transporters in Fatty Versus Lean Zucker Rats: a Follow-up Small Animal PET Study. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 17: 521-8. PMID 25537092 DOI: 10.1007/S11307-014-0811-7  0.395
2015 Cumming P, Skaper D, Kuwert T, Maschauer S, Prante O. Detection of monoamine oxidase a in brain of living rats with [18F]fluoroethyl-harmol PET. Synapse (New York, N.Y.). 69: 57-9. PMID 25229748 DOI: 10.1002/Syn.21785  0.381
2014 Jansen NL, Feuerecker R, Becker-Bense S, Zwergal A, Wulff M, Xiong G, Wängler B, Cumming P, Bartenstein P, Dieterich M, la Fougère C. Assessment of cerebral dopamine D 2/3 formula-receptors in patients with bilateral vestibular failure. Journal of Vestibular Research : Equilibrium & Orientation. 24: 403-13. PMID 25564083 DOI: 10.3233/Ves-140526  0.361
2014 Schabram I, Henkel K, Mohammadkhani Shali S, Dietrich C, Schmaljohann J, Winz O, Prinz S, Rademacher L, Neumaier B, Felzen M, Kumakura Y, Cumming P, Mottaghy FM, Gründer G, Vernaleken I. Acute and sustained effects of methylphenidate on cognition and presynaptic dopamine metabolism: an [18F]FDOPA PET study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14769-76. PMID 25355228 DOI: 10.1523/Jneurosci.1560-14.2014  0.421
2014 Lehner S, Todica A, Vanchev Y, Uebleis C, Wang H, Herrler T, Wängler C, Cumming P, Böning G, Franz WM, Bartenstein P, Hacker M, Brunner S. In vivo monitoring of parathyroid hormone treatment after myocardial infarction in mice with [68Ga]annexin A5 and [18F]fluorodeoxyglucose positron emission tomography. Molecular Imaging. 13. PMID 25249170 DOI: 10.2310/7290.2014.00035  0.318
2014 Cumming P. Measuring effects of MDMA (ecstasy) abuse on the rate of cerebral serotonin synthesis. Journal of Neurochemistry. 131: 541-5. PMID 25156194 DOI: 10.1111/Jnc.12848  0.334
2014 Rötering S, Deuther-Conrad W, Cumming P, Donat CK, Scheunemann M, Fischer S, Xiong G, Steinbach J, Peters D, Sabri O, Bucerius J, Brust P. Imaging of α7 nicotinic acetylcholine receptors in brain and cerebral vasculature of juvenile pigs with [(18)F]NS14490. Ejnmmi Research. 4: 43. PMID 25136512 DOI: 10.1186/S13550-014-0043-5  0.361
2014 Gryglewski G, Lanzenberger R, Kranz GS, Cumming P. Meta-analysis of molecular imaging of serotonin transporters in major depression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1096-103. PMID 24802331 DOI: 10.1038/Jcbfm.2014.82  0.306
2014 Cumming P, Maschauer S, Riss PJ, Tschammer N, Fehler SK, Heinrich MR, Kuwert T, Prante O. Radiosynthesis and validation of ¹⁸F-FP-CMT, a phenyltropane with superior properties for imaging the dopamine transporter in living brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1148-56. PMID 24714035 DOI: 10.1038/Jcbfm.2014.63  0.444
2014 Hocke C, Cumming P, Maschauer S, Kuwert T, Gmeiner P, Prante O. Biodistribution studies of two 18F-labeled pyridinylphenyl amides as subtype selective radioligands for the dopamine D3 receptor. Nuclear Medicine and Biology. 41: 223-8. PMID 24480780 DOI: 10.1016/J.Nucmedbio.2013.12.014  0.443
2014 Conway CR, Chibnall JT, Cumming P, Mintun MA, Gebara MA, Perantie DC, Price JL, Cornell ME, McConathy JE, Gangwani S, Sheline YI. Antidepressant response to aripiprazole augmentation associated with enhanced FDOPA utilization in striatum: a preliminary PET study. Psychiatry Research. 221: 231-9. PMID 24468015 DOI: 10.1016/J.Pscychresns.2014.01.003  0.409
2014 Smits R, Fischer S, Hiller A, Deuther-Conrad W, Wenzel B, Patt M, Cumming P, Steinbach J, Sabri O, Brust P, Hoepping A. Synthesis and biological evaluation of both enantiomers of [(18)F]flubatine, promising radiotracers with fast kinetics for the imaging of α4β2-nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry. 22: 804-12. PMID 24369841 DOI: 10.1016/J.Bmc.2013.12.011  0.32
2014 Brendel M, Delker A, Rötzer C, Böning G, Carlsen J, Cyran C, Mille E, Gildehaus FJ, Cumming P, Baumann K, Steiner H, Haass C, Herms J, Bartenstein P, Rominger A. Impact of partial volume effect correction on cerebral β-amyloid imaging in APP-Swe mice using [(18)F]-florbetaben PET. Neuroimage. 84: 843-53. PMID 24055703 DOI: 10.1016/J.Neuroimage.2013.09.017  0.391
2014 Cumming P. PET neuroimaging: the white elephant packs his trunk? Neuroimage. 84: 1094-100. PMID 23959198 DOI: 10.1016/J.Neuroimage.2013.08.020  0.331
2013 Schlüter T, Winz O, Henkel K, Prinz S, Rademacher L, Schmaljohann J, Dautzenberg K, Cumming P, Kumakura Y, Rex S, Mottaghy FM, Gründer G, Vernaleken I. The impact of dopamine on aggression: an [18F]-FDOPA PET Study in healthy males. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16889-96. PMID 24155295 DOI: 10.1523/Jneurosci.1398-13.2013  0.386
2013 Kalbitzer J, Kalbitzer U, Knudsen GM, Cumming P, Heinz A. How the cerebral serotonin homeostasis predicts environmental changes: a model to explain seasonal changes of brain 5-HTT as intermediate phenotype of the 5-HTTLPR. Psychopharmacology. 230: 333-43. PMID 24150247 DOI: 10.1007/S00213-013-3308-1  0.306
2013 Kumakura Y, Gjedde A, Caprioli D, Kienast T, Beck A, Plotkin M, Schlagenhauf F, Vernaleken I, Gründer G, Bartenstein P, Heinz A, Cumming P. Increased turnover of dopamine in caudate nucleus of detoxified alcoholic patients. Plos One. 8: e73903. PMID 24040111 DOI: 10.1371/Journal.Pone.0073903  0.398
2013 Uebleis C, Hellweger S, Laubender RP, Becker A, Sohn HY, Lehner S, Haug A, Bartenstein P, Cumming P, Van Kriekinge SD, Slomka PJ, Hacker M. The amount of dysfunctional but viable myocardium predicts long-term survival in patients with ischemic cardiomyopathy and left ventricular dysfunction. The International Journal of Cardiovascular Imaging. 29: 1645-53. PMID 23744128 DOI: 10.1007/S10554-013-0254-2  0.314
2013 Rominger A, Brendel M, Burgold S, Keppler K, Baumann K, Xiong G, Mille E, Gildehaus FJ, Carlsen J, Schlichtiger J, Niedermoser S, Wängler B, Cumming P, Steiner H, Herms J, et al. Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing Swedish mutant β-amyloid precursor protein using 18F-florbetaben PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1127-34. PMID 23729696 DOI: 10.2967/Jnumed.112.114660  0.378
2013 Rominger A, Cumming P, Xiong G, Koller G, Förster S, Zwergal A, Karamatskos E, Bartenstein P, La Fougère C, Pogarell O. Effects of acute detoxification of the herbal blend 'Spice Gold' on dopamine D2/3 receptor availability: a [18F]fallypride PET study. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 1606-10. PMID 23452563 DOI: 10.1016/J.Euroneuro.2013.01.009  0.435
2013 Fischer S, Hiller A, Smits R, Hoepping A, Funke U, Wenzel B, Cumming P, Sabri O, Steinbach J, Brust P. Radiosynthesis of racemic and enantiomerically pure (-)-[18F]flubatine--a promising PET radiotracer for neuroimaging of α4β2 nicotinic acetylcholine receptors. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 74: 128-36. PMID 23416407 DOI: 10.1016/J.Apradiso.2013.01.002  0.335
2013 Todica A, Brunner S, Böning G, Lehner S, Nekolla SG, Wildgruber M, Ãœbleis C, Wängler C, Sauter M, Klingel K, Cumming P, Bartenstein P, Schirrmacher R, Franz WM, Hacker M. [68Ga]-albumin-PET in the monitoring of left ventricular function in murine models of ischemic and dilated cardiomyopathy: comparison with cardiac MRI. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 15: 441-9. PMID 23408338 DOI: 10.1007/S11307-013-0618-Y  0.31
2013 Jupp B, Caprioli D, Saigal N, Reverte I, Shrestha S, Cumming P, Everitt BJ, Robbins TW, Dalley JW. Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex. The European Journal of Neuroscience. 37: 1519-28. PMID 23368520 DOI: 10.1111/Ejn.12146  0.352
2013 Kienast T, Schlagenhauf F, Rapp MA, Wrase J, Daig I, Buchholz HG, Smolka MN, Gründer G, Kumakura Y, Cumming P, Charlet K, Bartenstein P, Hariri AR, Heinz A. Dopamine-modulated aversive emotion processing fails in alcohol-dependent patients. Pharmacopsychiatry. 46: 130-6. PMID 23364872 DOI: 10.1055/S-0032-1331747  0.329
2013 Walter B, Eiselt M, Cumming P, Xiong G, Hinz R, Uthe S, Brust P, Bauer R. Resistance of brain glucose metabolism to thiopental-induced CNS depression in newborn piglets. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 31: 157-64. PMID 23305916 DOI: 10.1016/J.Ijdevneu.2012.12.008  0.376
2013 Todica A, Böning G, Lehner S, Weidl E, Cumming P, Wängler C, Nekolla SG, Schwaiger M, Bartenstein P, Schirrmacher R, Hacker M. Positron emission tomography in the assessment of left ventricular function in healthy rats: a comparison of four imaging methods. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 20: 262-74. PMID 23255241 DOI: 10.1007/S12350-012-9663-1  0.325
2013 Cumming P, Xiong G, la Fougère C, Rominger A, Bartenstein P, Buchholz HG, Piel M, Rösch F, Gründer G, Vernaleken I. Surrogate markers for cerebral blood flow correlate with [¹⁸F]-fallypride binding potential at dopamine D(2/3) receptors in human striatum. Synapse (New York, N.Y.). 67: 199-203. PMID 23239525 DOI: 10.1002/Syn.21630  0.44
2013 Vernaleken I, Klomp M, Moeller O, Raptis M, Nagels A, Rösch F, Schaefer WM, Cumming P, Gründer G. Vulnerability to psychotogenic effects of ketamine is associated with elevated D2/3-receptor availability. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 745-54. PMID 22906553 DOI: 10.1017/S1461145712000764  0.439
2013 Schlagenhauf F, Rapp MA, Huys QJ, Beck A, Wüstenberg T, Deserno L, Buchholz HG, Kalbitzer J, Buchert R, Bauer M, Kienast T, Cumming P, Plotkin M, Kumakura Y, Grace AA, et al. Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence. Human Brain Mapping. 34: 1490-9. PMID 22344813 DOI: 10.1002/Hbm.22000  0.337
2012 Jansen NL, Schwartz C, Graute V, Eigenbrod S, Lutz J, Egensperger R, Pöpperl G, Kretzschmar HA, Cumming P, Bartenstein P, Tonn JC, Kreth FW, la Fougère C, Thon N. Prediction of oligodendroglial histology and LOH 1p/19q using dynamic [(18)F]FET-PET imaging in intracranial WHO grade II and III gliomas. Neuro-Oncology. 14: 1473-80. PMID 23090986 DOI: 10.1093/Neuonc/Nos259  0.301
2012 Lehner S, Todica A, Brunner S, Uebleis C, Wang H, Wängler C, Herbach N, Herrler T, Böning G, Laubender RP, Cumming P, Schirrmacher R, Franz W, Hacker M. Temporal changes in phosphatidylserine expression and glucose metabolism after myocardial infarction: an in vivo imaging study in mice. Molecular Imaging. 11: 461-70. PMID 23084247 DOI: 10.2310/7290.2012.00010  0.326
2012 Brunner S, Todica A, Böning G, Nekolla SG, Wildgruber M, Lehner S, Sauter M, Ubleis C, Klingel K, Cumming P, Franz WM, Hacker M. Left ventricular functional assessment in murine models of ischemic and dilated cardiomyopathy using [18 F]FDG-PET: comparison with cardiac MRI and monitoring erythropoietin therapy. Ejnmmi Research. 2: 43. PMID 22863174 DOI: 10.1186/2191-219X-2-43  0.346
2012 Jansen NL, Graute V, Armbruster L, Suchorska B, Lutz J, Eigenbrod S, Cumming P, Bartenstein P, Tonn JC, Kreth FW, la Fougère C. MRI-suspected low-grade glioma: is there a need to perform dynamic FET PET? European Journal of Nuclear Medicine and Molecular Imaging. 39: 1021-9. PMID 22491781 DOI: 10.1007/S00259-012-2109-9  0.304
2012 Mille E, Cumming P, Rominger A, La Fougère C, Tatsch K, Wängler B, Bartenstein P, Böning G. Compensation for cranial spill-in into the cerebellum improves quantitation of striatal dopamine Dâ‚‚/₃ receptors in rats with prolonged [¹⁸F]-DMFP infusions. Synapse (New York, N.Y.). 66: 705-13. PMID 22460766 DOI: 10.1002/Syn.21558  0.444
2012 Virdee K, Cumming P, Caprioli D, Jupp B, Rominger A, Aigbirhio FI, Fryer TD, Riss PJ, Dalley JW. Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders. Neuroscience and Biobehavioral Reviews. 36: 1188-216. PMID 22342372 DOI: 10.1016/J.Neubiorev.2012.01.009  0.427
2012 Cumming P, Borghammer P. Molecular imaging and the neuropathologies of Parkinson's disease. Current Topics in Behavioral Neurosciences. 11: 117-48. PMID 22034053 DOI: 10.1007/7854_2011_165  0.322
2012 Rominger A, Cumming P, Xiong G, Koller G, Böning G, Wulff M, Zwergal A, Förster S, Reilhac A, Munk O, Soyka M, Wängler B, Bartenstein P, la Fougère C, Pogarell O. [18F]Fallypride PET measurement of striatal and extrastriatal dopamine D 2/3 receptor availability in recently abstinent alcoholics. Addiction Biology. 17: 490-503. PMID 22023291 DOI: 10.1111/J.1369-1600.2011.00355.X  0.404
2012 Borghammer P, Cumming P, Østergaard K, Gjedde A, Rodell A, Bailey CJ, Vafaee MS. Cerebral oxygen metabolism in patients with early Parkinson's disease. Journal of the Neurological Sciences. 313: 123-8. PMID 21975016 DOI: 10.1016/J.Jns.2011.09.010  0.322
2012 Ersche KD, Cumming P, Craig KJ, Müller U, Fineberg NA, Bullmore ET, Robbins TW. Amisulpride-induced acute akathisia in OCD: an example of dysfunctional dopamine-serotonin interactions? Journal of Psychopharmacology (Oxford, England). 26: 887-90. PMID 21746752 DOI: 10.1177/0269881111405363  0.307
2012 Deutschlander A, Fougere CL, Xiong GM, Bötzel K, Gründer G, Cumming P. Therapeutic Occupancy of the D2/3-Preferring Dopamine Receptor Agonist Pramipexol in Brains of Patients with Parkinson's Disease ([18F]-Fallypride PET Study) (P03.126) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P03.126  0.419
2012 Rominger A, Brendel M, Baumann K, Gildehaus F, Niedermoser S, Wängler B, Burgold S, Herms J, Cumming P, Steiner H, Haass C, Bartenstein P. Longitudinal imaging of cerebral beta-amyloid in APP-swe mice using [18F]florbetaben PET Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.411  0.316
2012 Rominger A, Brendel M, Baumann K, Gildehaus F, Niedermoser S, Wängler B, Burgold S, Herms J, Cumming P, Steiner H, Haass C, Bartenstein P. Longitudinal imaging of cerebral Aβ in APP-Swe mice using [18F]florbetaben PET Alzheimers & Dementia. 8: 11. DOI: 10.1016/J.Jalz.2012.05.033  0.331
2011 Deuther-Conrad W, Fischer S, Hiller A, Becker G, Cumming P, Xiong G, Funke U, Sabri O, Peters D, Brust P. Assessment of α7 nicotinic acetylcholine receptor availability in juvenile pig brain with [¹⁸F]NS10743. European Journal of Nuclear Medicine and Molecular Imaging. 38: 1541-9. PMID 21484373 DOI: 10.1007/S00259-011-1808-Y  0.348
2011 Cumming P. Absolute abundances and affinity states of dopamine receptors in mammalian brain: A review. Synapse (New York, N.Y.). 65: 892-909. PMID 21308799 DOI: 10.1002/Syn.20916  0.374
2011 Palner M, Kjaerby C, Knudsen GM, Cumming P. Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat. Neurochemistry International. 58: 243-7. PMID 21163313 DOI: 10.1016/J.Neuint.2010.12.007  0.411
2011 Uebleis C, Ulbrich M, Tegtmeyer R, Schuessler F, Haserueck N, Siebermair J, Becker C, Nekolla S, Cumming P, Bartenstein P, Kääb S, Hacker M. Electrocardiogram-gated 18F-FDG PET/CT hybrid imaging in patients with unsatisfactory response to cardiac resynchronization therapy: initial clinical results. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 67-71. PMID 21149479 DOI: 10.2967/Jnumed.110.078709  0.332
2011 Cumming P, Caprioli D, Dalley JW. What have positron emission tomography and 'Zippy' told us about the neuropharmacology of drug addiction? British Journal of Pharmacology. 163: 1586-604. PMID 20846139 DOI: 10.1111/J.1476-5381.2010.01036.X  0.362
2010 Förster S, Vaitl A, Teipel SJ, Yakushev I, Mustafa M, la Fougère C, Rominger A, Cumming P, Bartenstein P, Hampel H, Hummel T, Buerger K, Hundt W, Steinbach S. Functional representation of olfactory impairment in early Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 22: 581-91. PMID 20847402 DOI: 10.3233/Jad-2010-091549  0.308
2010 Rominger A, Mille E, Zhang S, Böning G, Förster S, Nowak S, Gildehaus FJ, Wängler B, Bartenstein P, Cumming P. Validation of the octamouse for simultaneous 18F-fallypride small-animal PET recordings from 8 mice. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1576-83. PMID 20847158 DOI: 10.2967/Jnumed.110.078451  0.375
2010 Bartmann H, Fuest C, la Fougere C, Xiong G, Just T, Schlichtiger J, Winter P, Böning G, Wängler B, Pekcec A, Soerensen J, Bartenstein P, Cumming P, Potschka H. Imaging of P-glycoprotein-mediated pharmacoresistance in the hippocampus: proof-of-concept in a chronic rat model of temporal lobe epilepsy. Epilepsia. 51: 1780-90. PMID 20633036 DOI: 10.1111/J.1528-1167.2010.02671.X  0.357
2010 Vernaleken I, Janouschek H, Raptis M, Hellmann S, Veselinovic T, Bröcheler A, Boy C, Cumming P, Hiemke C, Rösch F, Schäfer WM, Gründer G. Dopamine D2/3 receptor occupancy by quetiapine in striatal and extrastriatal areas. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 951-60. PMID 20392299 DOI: 10.1017/S1461145710000374  0.409
2010 Rominger A, Mille E, Böning G, Wängler B, Josef Gildehaus F, Arszol C, Bartenstein P, Cumming P. α2-adrenergic drugs modulate the binding of [18F]fallypride to dopamine D2/3 receptors in striatum of living mouse. Synapse (New York, N.Y.). 64: 654-7. PMID 20336625 DOI: 10.1002/Syn.20785  0.394
2010 la Fougère C, Pöpperl G, Levin J, Wängler B, Böning G, Uebleis C, Cumming P, Bartenstein P, Bötzel K, Tatsch K. The value of the dopamine D2/3 receptor ligand 18F-desmethoxyfallypride for the differentiation of idiopathic and nonidiopathic parkinsonian syndromes. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 581-7. PMID 20237026 DOI: 10.2967/Jnumed.109.071811  0.412
2010 Gjedde A, Kumakura Y, Cumming P, Linnet J, Møller A. Inverted-U-shaped correlation between dopamine receptor availability in striatum and sensation seeking. Proceedings of the National Academy of Sciences of the United States of America. 107: 3870-5. PMID 20133675 DOI: 10.1073/Pnas.0912319107  0.38
2010 Minuzzi L, Cumming P. Agonist binding fraction of dopamine D2/3 receptors in rat brain: a quantitative autoradiographic study. Neurochemistry International. 56: 747-52. PMID 20117160 DOI: 10.1016/J.Neuint.2010.01.010  0.42
2010 Rominger A, Wagner E, Mille E, Böning G, Esmaeilzadeh M, Wängler B, Gildehaus FJ, Nowak S, Bruche A, Tatsch K, Bartenstein P, Cumming P. Endogenous competition against binding of [(18)F]DMFP and [(18)F]fallypride to dopamine D(2/3) receptors in brain of living mouse. Synapse (New York, N.Y.). 64: 313-22. PMID 19957365 DOI: 10.1002/Syn.20730  0.47
2010 Kumakura Y, Danielsen EH, Gjedde A, Vernaleken I, Buchholz HG, Heinz A, Gründer G, Bartenstein P, Cumming P. Elevated [(18)F]FDOPA utilization in the periaqueductal gray and medial nucleus accumbens of patients with early Parkinson's disease. Neuroimage. 49: 2933-9. PMID 19941962 DOI: 10.1016/J.Neuroimage.2009.11.035  0.41
2010 Förster S, Teipel S, Zach C, Rominger A, Cumming P, Fougere Cl, Yakushev I, Haslbeck M, Hampel H, Bartenstein P, Bürger K. FDG-PET mapping the brain substrates of visuo-constructive processing in Alzheimer's disease. Journal of Psychiatric Research. 44: 462-9. PMID 19875130 DOI: 10.1016/J.Jpsychires.2009.09.012  0.309
2010 la Fougère C, Böning G, Bartmann H, Wängler B, Nowak S, Just T, Wagner E, Winter P, Rominger A, Förster S, Gildehaus FJ, Rosa-Neto P, Minuzzi L, Bartenstein P, Potschka H, ... Cumming P, et al. Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: effects of the novel P-glycoprotein inhibitor tariquidar. Neuroimage. 49: 1406-15. PMID 19796699 DOI: 10.1016/J.Neuroimage.2009.09.048  0.4
2010 Ostergaard SD, Alstrup AK, Gramsbergen JB, Minuzzi L, Pedersen K, Jensen SB, Doudet D, Cumming P. MDMA-evoked changes in the binding of dopamine D(2) receptor ligands in striatum of rats with unilateral serotonin depletion. Synapse (New York, N.Y.). 64: 70-82. PMID 19768811 DOI: 10.1002/Syn.20706  0.41
2010 Yakushev IY, Dupont E, Buchholz HG, Tillmanns J, Debus F, Cumming P, Heimann A, Fellgiebel A, Luhmann HJ, Landvogt C, Werhahn KJ, Schreckenberger M, Potschka H, Bartenstein P. In vivo imaging of dopamine receptors in a model of temporal lobe epilepsy. Epilepsia. 51: 415-22. PMID 19694792 DOI: 10.1111/J.1528-1167.2009.02272.X  0.441
2010 Kumakura Y, Vernaleken I, Buchholz HG, Borghammer P, Danielsen E, Gründer G, Heinz A, Bartenstein P, Cumming P. Age-dependent decline of steady state dopamine storage capacity of human brain: an FDOPA PET study. Neurobiology of Aging. 31: 447-63. PMID 18541344 DOI: 10.1016/J.Neurobiolaging.2008.05.005  0.411
2009 Kumakura Y, Cumming P. PET studies of cerebral levodopa metabolism: a review of clinical findings and modeling approaches. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 15: 635-50. PMID 19793723 DOI: 10.1177/1073858409338217  0.42
2009 Borghammer P, Cumming P, Aanerud J, Förster S, Gjedde A. Subcortical elevation of metabolism in Parkinson's disease--a critical reappraisal in the context of global mean normalization. Neuroimage. 47: 1514-21. PMID 19465133 DOI: 10.1016/J.Neuroimage.2009.05.040  0.3
2009 Mörtberg E, Cumming P, Wiklund L, Rubertsson S. Cerebral metabolic rate of oxygen (CMRO2) in pig brain determined by PET after resuscitation from cardiac arrest. Resuscitation. 80: 701-6. PMID 19395145 DOI: 10.1016/J.Resuscitation.2009.03.005  0.36
2009 Kalbitzer J, Frokjaer VG, Erritzoe D, Svarer C, Cumming P, Nielsen FA, Hashemi SH, Baaré WF, Madsen J, Hasselbalch SG, Kringelbach ML, Mortensen EL, Knudsen GM. The personality trait openness is related to cerebral 5-HTT levels. Neuroimage. 45: 280-5. PMID 19135154 DOI: 10.1016/J.Neuroimage.2008.12.001  0.328
2008 Vernaleken I, Fellows C, Janouschek H, Bröcheler A, Veselinovic T, Landvogt C, Boy C, Buchholz HG, Spreckelmeyer K, Bartenstein P, Cumming P, Hiemke C, Rösch F, Schäfer W, Wong DF, et al. Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone). Journal of Clinical Psychopharmacology. 28: 608-17. PMID 19011428 DOI: 10.1097/Jcp.0B013E31818Ba2F6  0.357
2008 Kienast T, Hariri AR, Schlagenhauf F, Wrase J, Sterzer P, Buchholz HG, Smolka MN, Gründer G, Cumming P, Kumakura Y, Bartenstein P, Dolan RJ, Heinz A. Dopamine in amygdala gates limbic processing of aversive stimuli in humans. Nature Neuroscience. 11: 1381-2. PMID 18978778 DOI: 10.1038/Nn.2222  0.355
2008 Vernaleken I, Cumming P, Gründer G. Imaging studies - differential action of typical and atypical antipsychotics in a network perspective. Pharmacopsychiatry. 41: S60-9. PMID 18756422 DOI: 10.1055/S-0028-1082058  0.36
2008 Jensen SB, Di Santo R, Olsen AK, Pedersen K, Costi R, Cirilli R, Cumming P. Synthesis and cerebral uptake of 1-(1-[(11)C]methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone, a novel tracer for positron emission tomography studies of monoamine oxidase type A. Journal of Medicinal Chemistry. 51: 1617-22. PMID 18307289 DOI: 10.1021/Jm701378E  0.414
2008 Vernaleken I, Kumakura Y, Buchholz HG, Siessmeier T, Hilgers RD, Bartenstein P, Cumming P, Gründer G. Baseline [18F]-FDOPA kinetics are predictive of haloperidol-induced changes in dopamine turnover and cognitive performance: A positron emission tomography study in healthy subjects. Neuroimage. 40: 1222-31. PMID 18262797 DOI: 10.1016/J.Neuroimage.2007.12.045  0.404
2008 Borghammer P, Jonsdottir KY, Cumming P, Ostergaard K, Vang K, Ashkanian M, Vafaee M, Iversen P, Gjedde A. Normalization in PET group comparison studies--the importance of a valid reference region. Neuroimage. 40: 529-40. PMID 18258457 DOI: 10.1016/J.Neuroimage.2007.12.057  0.324
2008 Kienast T, Siessmeier T, Wrase J, Braus DF, Smolka MN, Buchholz HG, Rapp M, Schreckenberger M, Rösch F, Cumming P, Gruender G, Mann K, Bartenstein P, Heinz A. Ratio of dopamine synthesis capacity to D2 receptor availability in ventral striatum correlates with central processing of affective stimuli. European Journal of Nuclear Medicine and Molecular Imaging. 35: 1147-58. PMID 18202844 DOI: 10.1007/S00259-007-0683-Z  0.38
2008 Landvogt C, Mengel E, Bartenstein P, Buchholz HG, Schreckenberger M, Siessmeier T, Scheurich A, Feldmann R, Weglage J, Cumming P, Zepp F, Ullrich K. Reduced cerebral fluoro-L-dopamine uptake in adult patients suffering from phenylketonuria. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 824-31. PMID 17971791 DOI: 10.1038/Sj.Jcbfm.9600571  0.374
2008 Borghammer P, Vafaee M, Ostergaard K, Rodell A, Bailey C, Cumming P. Effect of memantine on CBF and CMRO2 in patients with early Parkinson's disease. Acta Neurologica Scandinavica. 117: 317-23. PMID 17927800 DOI: 10.1111/J.1600-0404.2007.00943.X  0.354
2008 Linnet J, Møller A, Kumakura Y, Cumming P, Gjedde A. Low dopamine receptor availability in brain of highly sensation-seeking men Neuroimage. 41: T131. DOI: 10.1016/J.Neuroimage.2008.04.099  0.372
2007 Kumakura Y, Cumming P, Vernaleken I, Buchholz HG, Siessmeier T, Heinz A, Kienast T, Bartenstein P, Gründer G. Elevated [18F]fluorodopamine turnover in brain of patients with schizophrenia: an [18F]fluorodopa/positron emission tomography study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8080-7. PMID 17652599 DOI: 10.1523/Jneurosci.0805-07.2007  0.405
2007 Mörtberg E, Cumming P, Wiklund L, Wall A, Rubertsson S. A PET study of regional cerebral blood flow after experimental cardiopulmonary resuscitation. Resuscitation. 75: 98-104. PMID 17499906 DOI: 10.1016/J.Resuscitation.2007.03.020  0.343
2007 Gramsbergen JB, Cumming P. Serotonin mediates rapid changes of striatal glucose and lactate metabolism after systemic 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") administration in awake rats. Neurochemistry International. 51: 8-15. PMID 17475367 DOI: 10.1016/J.Neuint.2007.03.004  0.31
2007 Lind NM, Moustgaard A, Jelsing J, Vajta G, Cumming P, Hansen AK. The use of pigs in neuroscience: modeling brain disorders. Neuroscience and Biobehavioral Reviews. 31: 728-51. PMID 17445892 DOI: 10.1016/J.Neubiorev.2007.02.003  0.319
2007 Cumming P, Møller M, Benda K, Minuzzi L, Jakobsen S, Jensen SB, Pakkenberg B, Stark AK, Gramsbergen JB, Andreasen MF, Olsen AK. A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on serotonin markers in Göttingen minipig brain. Synapse (New York, N.Y.). 61: 478-87. PMID 17415793 DOI: 10.1002/Syn.20377  0.398
2007 Mezzomo K, Cumming P, Minuzzi L. Comparison of the binding distribution of agonist and antagonist ligands for histamine H3 receptors in pig brain by quantitative autoradiography. European Journal of Pharmacology. 564: 75-9. PMID 17350614 DOI: 10.1016/J.Ejphar.2007.01.087  0.365
2007 Pedersen K, Simonsen M, Østergaard SD, Munk OL, Rosa-Neto P, Olsen AK, Jensen SB, Møller A, Cumming P. Mapping the amphetamine-evoked changes in [11C]raclopride binding in living rat using small animal PET: modulation by MAO-inhibition. Neuroimage. 35: 38-46. PMID 17223363 DOI: 10.1016/J.Neuroimage.2006.11.038  0.445
2007 Vernaleken I, Weibrich C, Siessmeier T, Buchholz HG, Rösch F, Heinz A, Cumming P, Stoeter P, Bartenstein P, Gründer G. Asymmetry in dopamine D(2/3) receptors of caudate nucleus is lost with age. Neuroimage. 34: 870-8. PMID 17174574 DOI: 10.1016/J.Neuroimage.2006.10.013  0.357
2007 Vernaleken I, Buchholz HG, Kumakura Y, Siessmeier T, Stoeter P, Bartenstein P, Cumming P, Gründer G. 'Prefrontal' cognitive performance of healthy subjects positively correlates with cerebral FDOPA influx: an exploratory [18F]-fluoro-L-DOPA-PET investigation. Human Brain Mapping. 28: 931-9. PMID 17133402 DOI: 10.1002/Hbm.20325  0.37
2006 Siessmeier T, Kienast T, Wrase J, Larsen JL, Braus DF, Smolka MN, Buchholz HG, Schreckenberger M, Rösch F, Cumming P, Mann K, Bartenstein P, Heinz A. Net influx of plasma 6-[18F]fluoro-L-DOPA (FDOPA) to the ventral striatum correlates with prefrontal processing of affective stimuli. The European Journal of Neuroscience. 24: 305-13. PMID 16882026 DOI: 10.1111/J.1460-9568.2006.04903.X  0.366
2006 Jakobsen S, Kodahl GM, Olsen AK, Cumming P. Synthesis, radiolabeling and in vivo evaluation of [11C]RAL-01, a potential phosphodiesterase 5 radioligand. Nuclear Medicine and Biology. 33: 593-7. PMID 16843833 DOI: 10.1016/J.Nucmedbio.2006.04.006  0.365
2006 Smith DF, Dyve S, Minuzzi L, Jakobsen S, Munk OL, Marthi K, Cumming P. Inhibition of [11C]mirtazapine binding by alpha2-adrenoceptor antagonists studied by positron emission tomography in living porcine brain. Synapse (New York, N.Y.). 59: 463-71. PMID 16565964 DOI: 10.1002/Syn.20262  0.402
2006 Iversen P, Hansen DA, Bender D, Rodell A, Munk OL, Cumming P, Keiding S. Peripheral benzodiazepine receptors in the brain of cirrhosis patients with manifest hepatic encephalopathy. European Journal of Nuclear Medicine and Molecular Imaging. 33: 810-6. PMID 16550382 DOI: 10.1007/S00259-005-0052-8  0.37
2006 Cumming P, Pedersen MD, Minuzzi L, Mezzomo K, Danielsen EH, Iversen P, Aagaard D, Keiding S, Munk OL, Finsen B. Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography. Synapse (New York, N.Y.). 59: 418-26. PMID 16485266 DOI: 10.1002/Syn.20257  0.422
2006 Jensen SB, Olsen AK, Pedersen K, Cumming P. Effect of monoamine oxidase inhibition on amphetamine-evoked changes in dopamine receptor availability in the living pig: a dual tracer PET study with [11C]harmine and [11C]raclopride. Synapse (New York, N.Y.). 59: 427-34. PMID 16485265 DOI: 10.1002/Syn.20258  0.397
2006 Vernaleken I, Kumakura Y, Cumming P, Buchholz HG, Siessmeier T, Stoeter P, Müller MJ, Bartenstein P, Gründer G. Modulation of [18F]fluorodopa (FDOPA) kinetics in the brain of healthy volunteers after acute haloperidol challenge. Neuroimage. 30: 1332-9. PMID 16439159 DOI: 10.1016/J.Neuroimage.2005.11.014  0.411
2006 Minuzzi L, Olsen AK, Bender D, Arnfred S, Grant R, Danielsen EH, Cumming P. Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of Göttingen minipig: comparison with results in vivo. Synapse (New York, N.Y.). 59: 211-9. PMID 16385509 DOI: 10.1002/Syn.20234  0.45
2006 Doudet DJ, Rosa-Neto P, Munk OL, Ruth TJ, Jivan S, Cumming P. Effect of age on markers for monoaminergic neurons of normal and MPTP-lesioned rhesus monkeys: a multi-tracer PET study. Neuroimage. 30: 26-35. PMID 16378735 DOI: 10.1016/J.Neuroimage.2005.09.044  0.395
2006 Smith DF, Marthi K, Munk OL, Cumming P, Hansen SB, Jakobsen S. PET neuroimaging of [11C]mirtazapine enantiomers in pigs. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 16: 350-7. PMID 16361085 DOI: 10.1016/J.Euroneuro.2005.10.008  0.37
2006 Kumakura Y, Gjedde A, Danielsen EH, Christensen S, Cumming P. Dopamine storage capacity in caudate and putamen of patients with early Parkinson's disease: correlation with asymmetry of motor symptoms. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 358-70. PMID 16079784 DOI: 10.1038/Sj.Jcbfm.9600202  0.377
2006 Peterson E, Gjedde A, Rodell A, Cumming P, Moller A, Linnet J. High sensation seeking men have increased dopamine binding in the right putamen during gambling, determined from raclopride binding potentials Neuroimage. 31: T168. DOI: 10.1016/J.Neuroimage.2006.04.151  0.338
2006 Smith DF, Marthi K, Jakobsen S, Bender D, Hansen S, Smith B, Hermansen F, Rosenberg R, Cumming P. PET neuroimaging of racemic [11C]mirtazapine and enantiomers: Pharmacokinetic models and alpha-noradrenergic binding sites Neuroimage. 31: T125. DOI: 10.1016/J.Neuroimage.2006.04.110  0.319
2006 Pedersen K, Gjedde A, Olsen Å, Jakobsen S, Cumming P, Jensen S. Binding of the hallucinogen [11C]MeO-DMT in the brain of living pigs Neuroimage. 31: T53. DOI: 10.1016/J.Neuroimage.2006.04.044  0.335
2005 Borghammer P, Kumakura Y, Cumming P. Fluorodopa F 18 positron emission tomography and the progression of Parkinson disease. Archives of Neurology. 62: 1480; author reply 1. PMID 16157762 DOI: 10.1001/Archneur.62.9.1480-A  0.332
2005 Heinz A, Siessmeier T, Wrase J, Buchholz HG, Gründer G, Kumakura Y, Cumming P, Schreckenberger M, Smolka MN, Rösch F, Mann K, Bartenstein P. Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients. The American Journal of Psychiatry. 162: 1515-20. PMID 16055774 DOI: 10.1176/Appi.Ajp.162.8.1515  0.352
2005 Lind NM, Gjedde A, Moustgaard A, Olsen AK, Jensen SB, Jakobsen S, Arnfred SM, Hansen AK, Hemmingsen RP, Cumming P. Behavioral response to novelty correlates with dopamine receptor availability in striatum of Göttingen minipigs. Behavioural Brain Research. 164: 172-7. PMID 16043240 DOI: 10.1016/J.Bbr.2005.06.008  0.399
2005 Siessmeier T, Zhou Y, Buchholz HG, Landvogt C, Vernaleken I, Piel M, Schirrmacher R, Rösch F, Schreckenberger M, Wong DF, Cumming P, Gründer G, Bartenstein P. Parametric mapping of binding in human brain of D2 receptor ligands of different affinities. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 46: 964-72. PMID 15937307  0.311
2005 Sørensen M, Horsman MR, Cumming P, Munk OL, Keiding S. Effect of intratumoral heterogeneity in oxygenation status on FMISO PET, autoradiography, and electrode Po2 measurements in murine tumors. International Journal of Radiation Oncology, Biology, Physics. 62: 854-61. PMID 15936570 DOI: 10.1016/J.Ijrobp.2005.02.044  0.321
2005 Andersen F, Watanabe H, Bjarkam C, Danielsen EH, Cumming P. Pig brain stereotaxic standard space: mapping of cerebral blood flow normative values and effect of MPTP-lesioning. Brain Research Bulletin. 66: 17-29. PMID 15925140 DOI: 10.1016/J.Brainresbull.2005.02.033  0.348
2005 Rosa-Neto P, Lou HC, Cumming P, Pryds O, Karrebaek H, Lunding J, Gjedde A. Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder. Neuroimage. 25: 868-76. PMID 15808987 DOI: 10.1016/J.Neuroimage.2004.11.031  0.343
2005 Minuzzi L, Nomikos GG, Wade MR, Jensen SB, Olsen AK, Cumming P. Interaction between LSD and dopamine D2/3 binding sites in pig brain. Synapse (New York, N.Y.). 56: 198-204. PMID 15803496 DOI: 10.1002/Syn.20141  0.448
2005 Gjedde A, Wong DF, Rosa-Neto P, Cumming P. Mapping neuroreceptors at work: on the definition and interpretation of binding potentials after 20 years of progress. International Review of Neurobiology. 63: 1-20. PMID 15797463 DOI: 10.1016/S0074-7742(05)63001-2  0.352
2005 Kumakura Y, Vernaleken I, Gründer G, Bartenstein P, Gjedde A, Cumming P. PET studies of net blood-brain clearance of FDOPA to human brain: age-dependent decline of [18F]fluorodopamine storage capacity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 807-19. PMID 15729292 DOI: 10.1038/Sj.Jcbfm.9600079  0.413
2005 Lind NM, Olsen AK, Moustgaard A, Jensen SB, Jakobsen S, Hansen AK, Arnfred SM, Hemmingsen RP, Gjedde A, Cumming P. Mapping the amphetamine-evoked dopamine release in the brain of the Göttingen minipig. Brain Research Bulletin. 65: 1-9. PMID 15680539 DOI: 10.1016/J.Brainresbull.2004.08.007  0.398
2005 Jelsing J, Olsen AK, Cumming P, Gjedde A, Hansen AK, Arnfred S, Hemmingsen R, Pakkenberg B. A volumetric screening procedure for the Göttingen minipig brain. Experimental Brain Research. 162: 428-35. PMID 15668795 DOI: 10.1007/S00221-004-2026-7  0.305
2005 Vernaleken I, Kumakura Y, Buchholz H, Siessmeier T, Bartenstein P, Cumming P, Gründer G. Prefrontal cognitive performance of healthy subjects positively correlates with 18F-FDOPA uptake in positron emission tomography Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918861  0.328
2004 Kumakura Y, Danielsen EH, Reilhac A, Gjedde A, Cumming P. Levodopa effect on [18F]fluorodopa influx to brain: normal volunteers and patients with Parkinson's disease. Acta Neurologica Scandinavica. 110: 188-95. PMID 15285777 DOI: 10.1111/J.1600-0404.2004.00299.X  0.427
2004 Rosa-Neto P, Gjedde A, Olsen AK, Jensen SB, Munk OL, Watanabe H, Cumming P. MDMA-evoked changes in [11C]raclopride and [11C]NMSP binding in living pig brain. Synapse (New York, N.Y.). 53: 222-33. PMID 15266554 DOI: 10.1002/Syn.20053  0.446
2004 Rosa-Neto P, Olsen AK, Gjedde A, Watanabe H, Cumming P. MDMA-evoked changes in cerebral blood flow in living porcine brain: correlation with hyperthermia. Synapse (New York, N.Y.). 53: 214-21. PMID 15266553 DOI: 10.1002/Syn.20052  0.389
2004 Bender D, Olsen AK, Marthi MK, Smith DF, Cumming P. PET evaluation of the uptake of N-[11C]methyl CP-643,051, an NK1 receptor antagonist, in the living porcine brain. Nuclear Medicine and Biology. 31: 699-704. PMID 15246360 DOI: 10.1016/J.Nucmedbio.2004.03.005  0.375
2004 Rosa-Neto P, Doudet DJ, Cumming P. Gradients of dopamine D1- and D2/3-binding sites in the basal ganglia of pig and monkey measured by PET. Neuroimage. 22: 1076-83. PMID 15219579 DOI: 10.1016/J.Neuroimage.2004.03.004  0.432
2004 Vafaee MS, ØStergaard K, Sunde N, Gjedde A, Dupont E, Cumming P. Focal changes of oxygen consumption in cerebral cortex of patients with Parkinson's disease during subthalamic stimulation. Neuroimage. 22: 966-74. PMID 15193628 DOI: 10.1016/J.Neuroimage.2004.02.019  0.336
2004 Lou HC, Rosa P, Pryds O, Karrebaek H, Lunding J, Cumming P, Gjedde A. ADHD: increased dopamine receptor availability linked to attention deficit and low neonatal cerebral blood flow. Developmental Medicine and Child Neurology. 46: 179-83. PMID 14995087 DOI: 10.1017/S0012162204000313  0.343
2003 Kretzschmar M, Brust P, Zessin J, Cumming P, Bergmann R, Johannsen B. Autoradiographic imaging of the serotonin transporter in the brain of rats and pigs using S-([18F]fluoromethyl)-(+)-McN5652. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 13: 387-97. PMID 12957338 DOI: 10.1016/S0924-977X(03)00039-7  0.416
2003 Cumming P, Rosa-Neto P, Watanabe H, Smith D, Bender D, Clarke PB, Gjedde A. Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain. Neuroimage. 19: 1127-36. PMID 12880838 DOI: 10.1016/S1053-8119(03)00079-X  0.404
2003 Cumming P, Gillings NM, Jensen SB, Bjarkam C, Gjedde A. Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs. Nuclear Medicine and Biology. 30: 547-53. PMID 12831994 DOI: 10.1016/S0969-8051(02)00448-1  0.458
2003 Jensen SB, Smith DF, Bender D, Jakobsen S, Peters D, Nielsen EØ, Olsen GM, Scheel-Krüger J, Wilson A, Cumming P. [11C]-NS 4194 versus [11C]-DASB for PET imaging of serotonin transporters in living porcine brain. Synapse (New York, N.Y.). 49: 170-7. PMID 12774301 DOI: 10.1002/Syn.10222  0.396
2003 Gründer G, Vernaleken I, Müller MJ, Davids E, Heydari N, Buchholz HG, Bartenstein P, Munk OL, Stoeter P, Wong DF, Gjedde A, Cumming P. Subchronic haloperidol downregulates dopamine synthesis capacity in the brain of schizophrenic patients in vivo. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 787-94. PMID 12655326 DOI: 10.1038/Sj.Npp.1300103  0.418
2003 Audrain H, Bender D, Scheel-Krüger J, Nielsen E, Olsen GM, Peters D, Cumming P. Synthesis of the serotonin transporter ligand (±)-10-methyl 3-[6-nitro-(2-quinolinyl)]-3,10-diazabicyclo-[4.3.1]-decane ([ 11C-methyl]NS 2495) and first in vivo results Journal of Labelled Compounds and Radiopharmaceuticals. 46: 873-882. DOI: 10.1002/Jlcr.726  0.382
2002 Dall AM, Danielsen EH, Sørensen JC, Andersen F, Møller A, Zimmer J, Gjedde AH, Cumming P. Quantitative [18F]fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned minipigs. Cell Transplantation. 11: 733-46. PMID 12588105 DOI: 10.3727/000000002783985314  0.326
2002 Pradhan AA, Cumming P, Clarke PB. [125I]Epibatidine-labelled nicotinic receptors in the extended striatum and cerebral cortex: lack of association with serotonergic afferents. Brain Research. 954: 227-36. PMID 12414106 DOI: 10.1016/S0006-8993(02)03340-1  0.358
2002 Cumming P, Wong DF, Dannals RF, Gillings N, Hilton J, Scheffel U, Gjedde A. The competition between endogenous dopamine and radioligands for specific binding to dopamine receptors. Annals of the New York Academy of Sciences. 965: 440-50. PMID 12105119 DOI: 10.1111/J.1749-6632.2002.Tb04185.X  0.402
2002 Rosa Neto P, Lou H, Cumming P, Pryds O, Gjedde A. Methylphenidate-evoked potentiation of extracellular dopamine in the brain of adolescents with premature birth: correlation with attentional deficit. Annals of the New York Academy of Sciences. 965: 434-9. PMID 12105118 DOI: 10.1111/J.1749-6632.2002.Tb04184.X  0.376
2002 Cumming P, Wong DF, Gillings N, Hilton J, Scheffel U, Gjedde A. Specific binding of [(11)C]raclopride and N-[(3)H]propyl-norapomorphine to dopamine receptors in living mouse striatum: occupancy by endogenous dopamine and guanosine triphosphate-free G protein. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 596-604. PMID 11973432 DOI: 10.1097/00004647-200205000-00011  0.395
2001 Watanabe H, Andersen F, Simonsen CZ, Evans SM, Gjedde A, Cumming P. MR-based statistical atlas of the Göttingen minipig brain. Neuroimage. 14: 1089-96. PMID 11697940 DOI: 10.1006/Nimg.2001.0910  0.374
2001 Dagher A, Bleicher C, Aston JA, Gunn RN, Clarke PB, Cumming P. Reduced dopamine D1 receptor binding in the ventral striatum of cigarette smokers. Synapse (New York, N.Y.). 42: 48-53. PMID 11668590 DOI: 10.1002/Syn.1098  0.363
2001 Danielsen EH, Smith DF, Andersen F, Gee AD, Bender D, Hansen SB, Hermansen F, Østergaard L, Cumming P, Gjedde A. FDOPA metabolism in the adult porcine brain: influence of tracer circulation time and VOI selection on estimates of striatal DOPA decarboxylation. Journal of Neuroscience Methods. 111: 157-68. PMID 11595282 DOI: 10.1016/S0165-0270(01)00453-8  0.382
2001 Danielsen EH, Smith D, Hermansen F, Gjedde A, Cumming P. Acute neuroleptic stimulates DOPA decarboxylase in porcine brain in vivo. Synapse (New York, N.Y.). 41: 172-5. PMID 11400183 DOI: 10.1002/Syn.1071  0.421
2001 Cumming P, Munk OL, Doudet D. Loss of metabolites from monkey striatum during PET with FDOPA. Synapse (New York, N.Y.). 41: 212-8. PMID 11391782 DOI: 10.1002/Syn.1077  0.369
2001 Cumming P, Danielsen EH, Vafaee M, Falborg L, Steffensen E, Sørensen JC, Gillings N, Bender D, Marthi K, Andersen F, Munk O, Smith D, Møller A, Gjedde A. Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts. Acta Neurologica Scandinavica. 103: 309-15. PMID 11328207 DOI: 10.1034/J.1600-0404.2001.103005309.X  0.416
2001 Smith DF, Bender D, Marthi K, Cumming P, Hansen SB, Peters D, Nielsen EO, Scheel-Krüger J, Gjedde A. Synthesis and evaluation of racemic [(11)C]NS2456 and enantiomers as selective serotonin reuptake radiotracers for PET. Nuclear Medicine and Biology. 28: 265-70. PMID 11323236 DOI: 10.1016/S0969-8051(00)00175-X  0.42
2001 Gillings NM, Bender D, Falborg L, Marthi K, Munk OL, Cumming P. Kinetics of the metabolism of four PET radioligands in living minipigs. Nuclear Medicine and Biology. 28: 97-104. PMID 11182570 DOI: 10.1016/S0969-8051(00)00187-6  0.31
2001 Cumming P, Kretzschmar M, Brust P, Smith DF. Quantitative radioluminography of serotonin uptake sites in the porcine brain. Synapse (New York, N.Y.). 39: 351-5. PMID 11169786 DOI: 10.1002/1098-2396(20010315)39:4<351::Aid-Syn1019>3.0.Co;2-M  0.389
2001 Smith DF, Bender D, Marthi K, Cumming P, Hansen SB, Peters D, Nielsen EØ, Scheel-Krüger J, Gjedde A. Synthesis and in vivo evaluation (PIG) of the selective seretonin reuptake inhibitor [11C]NS 2456 Journal of Labelled Compounds and Radiopharmaceuticals. 44: S198-S200. DOI: 10.1002/Jlcr.2580440169  0.392
2000 Ishizu K, Smith DF, Bender D, Danielsen E, Hansen SB, Wong DF, Cumming P, Gjedde A. Positron emission tomography of radioligand binding in porcine striatum in vivo: haloperidol inhibition linked to endogenous ligand release. Synapse (New York, N.Y.). 38: 87-101. PMID 10941144 DOI: 10.1002/1098-2396(200010)38:1<87::Aid-Syn10>3.0.Co;2-C  0.397
2000 Rousset OG, Deep P, Kuwabara H, Evans AC, Gjedde AH, Cumming P. Effect of partial volume correction on estimates of the influx and cerebral metabolism of 6-[(18)F]fluoro-L-dopa studied with PET in normal control and Parkinson's disease subjects. Synapse (New York, N.Y.). 37: 81-9. PMID 10881028 DOI: 10.1002/1098-2396(200008)37:2<81::Aid-Syn1>3.0.Co;2-#  0.428
2000 Marenco T, Bernstein S, Cumming P, Clarke PB. Effects of nicotine and chlorisondamine on cerebral glucose utilization in immobilized and freely-moving rats. British Journal of Pharmacology. 129: 147-55. PMID 10694214 DOI: 10.1038/Sj.Bjp.0703005  0.309
1999 Deep P, Dagher A, Sadikot A, Gjedde A, Cumming P. Stimulation of dopa decarboxylase activity in striatum of healthy human brain secondary to NMDA receptor antagonism with a low dose of amantadine. Synapse (New York, N.Y.). 34: 313-8. PMID 10529725 DOI: 10.1002/(Sici)1098-2396(19991215)34:4<313::Aid-Syn7>3.0.Co;2-1  0.416
1999 Cumming P, Hermansen F, Gjedde A. Cerebral dopamine concentrations during levodopa treatment. Neurology. 53: 1374-5. PMID 10522916 DOI: 10.1212/Wnl.53.6.1374  0.313
1999 Cumming P, Yokoi F, Chen A, Deep P, Dagher A, Reutens D, Kapczinski F, Wong DF, Gjedde A. Pharmacokinetics of radiotracers in human plasma during positron emission tomography. Synapse (New York, N.Y.). 34: 124-34. PMID 10502311 DOI: 10.1002/(Sici)1098-2396(199911)34:2<124::Aid-Syn5>3.0.Co;2-O  0.379
1999 Danielsen EH, Smith DF, Gee AD, Venkatachalam TK, Hansen SB, Hermansen F, Gjedde A, Cumming P. Cerebral 6-[(18)F]fluoro-L-DOPA (FDOPA) metabolism in pig studied by positron emission tomography. Synapse (New York, N.Y.). 33: 247-58. PMID 10421705 DOI: 10.1002/(Sici)1098-2396(19990915)33:4<247::Aid-Syn1>3.0.Co;2-6  0.4
1998 Léger G, Gjedde A, Kuwabara H, Guttman M, Cumming P. Effect of catechol-O-methyltransferase inhibition on brain uptake of [18F]fluorodopa: implications for compartmental modelling and clinical usefulness. Synapse (New York, N.Y.). 30: 351-61. PMID 9826227 DOI: 10.1002/(Sici)1098-2396(199812)30:4<351::Aid-Syn2>3.0.Co;2-2  0.433
1998 Cumming P, Ase A, Kuwabara H, Gjedde A. [3H]DOPA formed from [3H]tyrosine in living rat brain is not committed to dopamine synthesis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 491-9. PMID 9591841 DOI: 10.1097/00004647-199805000-00004  0.415
1998 Reith J, Cumming P, Gjedde A. Enhanced [3H]DOPA and [3H]dopamine turnover in striatum and frontal cortex in vivo linked to glutamate receptor antagonism. Journal of Neurochemistry. 70: 1979-85. PMID 9572282 DOI: 10.1046/J.1471-4159.1998.70051979.X  0.394
1998 Cumming P, Gjedde A. Compartmental analysis of dopa decarboxylation in living brain from dynamic positron emission tomograms. Synapse (New York, N.Y.). 29: 37-61. PMID 9552174 DOI: 10.1002/(Sici)1098-2396(199805)29:1<37::Aid-Syn4>3.0.Co;2-C  0.412
1997 Cumming P, Deep P, Rousset O, Evans A, Gjedde A. On the rate of decarboxylation of dopa to dopamine in living mammalian brain. Annals of the New York Academy of Sciences. 835: 274-308. PMID 9616781 DOI: 10.1111/J.1749-6632.1997.Tb48637.X  0.378
1997 Deep P, Kuwabara H, Gjedde A, Cumming P. The kinetic behaviour of [3H]DOPA in living rat brain investigated by compartmental modelling of static autoradiograms. Journal of Neuroscience Methods. 78: 157-68. PMID 9497012 DOI: 10.1016/S0165-0270(97)00147-7  0.38
1997 Cumming P, Ase A, Laliberté C, Kuwabara H, Gjedde A. In vivo regulation of DOPA decarboxylase by dopamine receptors in rat brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 1254-60. PMID 9390657 DOI: 10.1097/00004647-199711000-00014  0.407
1997 Deep P, Gjedde A, Cumming P. On the accuracy of an [18F]FDOPA compartmental model: evidence for vesicular storage of [18F]fluorodopamine in vivo. Journal of Neuroscience Methods. 76: 157-65. PMID 9350967 DOI: 10.1016/S0165-0270(97)00094-0  0.325
1997 Cumming P, Ljubic-Thibal V, Laliberté C, Diksic M. The effect of unilateral neurotoxic lesions to serotonin fibres in the medial forebrain bundle on the metabolism of [3H]DOPA in the telencephalon of the living rat. Brain Research. 747: 60-9. PMID 9042528 DOI: 10.1016/S0006-8993(96)01227-9  0.343
1997 Benkelfat C, Nishizawa S, Kuwabara H, Lal S, Chouinard G, Cumming P, Labelle A, Joober R, Bruce K, Dikksic M, Gjedde A. Brain dopa-decarboxylase (DDC) activity in unmedicated schizophrenic patients Schizophrenia Research. 24: 176. DOI: 10.1016/S0920-9964(97)82505-4  0.323
1997 Reith J, Cumming P, Gjedde A. 2-30-26 Chronic glutamate receptor antagonism linked to markedly enhanced activities of enzymes of dopamine synthesis and breakdown in vivo Journal of the Neurological Sciences. 150: S114. DOI: 10.1016/S0022-510X(97)85404-4  0.309
1995 Cumming P, Kuwabara H, Ase A, Gjedde A. Regulation of DOPA decarboxylase activity in brain of living rat. Journal of Neurochemistry. 65: 1381-90. PMID 7643116 DOI: 10.1046/J.1471-4159.1995.65031381.X  0.384
1995 Cumming P, Ase A, Diksic M, Harrison J, Jolly D, Kuwabara H, Laliberté C, Gjedde A. Metabolism and blood-brain clearance of L-3,4-dihydroxy-[3H]phenylalanine ([3H]DOPA) and 6-[18F]fluoro-L-DOPA in the rat. Biochemical Pharmacology. 50: 943-6. PMID 7575677 DOI: 10.1016/0006-2952(95)00216-M  0.39
1994 Cumming P, Gjedde A. Subclasses of histamine H3 antagonist binding sites in rat brain. Brain Research. 641: 203-7. PMID 8012822 DOI: 10.1016/0006-8993(94)90147-3  0.339
1994 Cumming P, Gjedde A, Vincent S. Histamine H3 binding sites in rat brain: localization in the nucleus of the solitary tract. Brain Research. 641: 198-202. PMID 8012821 DOI: 10.1016/0006-8993(94)90146-5  0.586
1994 Reith J, Benkelfat C, Sherwin A, Yasuhara Y, Kuwabara H, Andermann F, Bachneff S, Cumming P, Diksic M, Dyve SE, Etienne P, Evans AC, Lal S, Shevell M, Savard G, et al. Elevated dopa decarboxylase activity in living brain of patients with psychosis. Proceedings of the National Academy of Sciences of the United States of America. 91: 11651-4. PMID 7972118 DOI: 10.1073/Pnas.91.24.11651  0.364
1994 Cumming P, Kuwabara H, Gjedde A. A kinetic analysis of 6-[18F]fluoro-L-dihydroxyphenylalanine metabolism in the rat. Journal of Neurochemistry. 63: 1675-82. PMID 7931323 DOI: 10.1046/J.1471-4159.1994.63051675.X  0.326
1994 Cumming P, Venkatachalam TK, Rajagopal S, Diksic M, Gjedde A. Brain uptake of alpha-[14C]methyl-para-tyrosine in the rat. Synapse (New York, N.Y.). 17: 125-8. PMID 7916491 DOI: 10.1002/Syn.890170208  0.358
1994 Cumming P, Laliberté C, Gjedde A. Distribution of histamine H3 binding in forebrain of mouse and guinea pig. Brain Research. 664: 276-9. PMID 7895042 DOI: 10.1016/0006-8993(94)91985-2  0.333
1993 Hoshi H, Kuwabara H, Léger G, Cumming P, Guttman M, Gjedde A. 6-[18F]fluoro-L-dopa metabolism in living human brain: a comparison of six analytical methods. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 57-69. PMID 8417011 DOI: 10.1038/Jcbfm.1993.8  0.319
1993 Kuwabara H, Cumming P, Reith J, Léger G, Diksic M, Evans AC, Gjedde A. Human striatal L-dopa decarboxylase activity estimated in vivo using 6-[18F]fluoro-dopa and positron emission tomography: error analysis and application to normal subjects. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 43-56. PMID 8417009 DOI: 10.1038/Jcbfm.1993.7  0.42
1993 Cumming P, Vincent SR. Altered histamine H3 binding in rat forebrain after reserpine treatment. Brain Research. 602: 53-6. PMID 8383572 DOI: 10.1016/0006-8993(93)90240-N  0.589
1993 Gjedde A, Léger GC, Cumming P, Yasuhara Y, Evans AC, Guttman M, Kuwabara H. Striatal L-dopa decarboxylase activity in Parkinson's disease in vivo: implications for the regulation of dopamine synthesis. Journal of Neurochemistry. 61: 1538-41. PMID 8377003 DOI: 10.1111/J.1471-4159.1993.Tb13651.X  0.351
1993 Cumming P, Léger GC, Kuwabara H, Gjedde A. Pharmacokinetics of plasma 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine ([18F]Fdopa) in humans. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 668-75. PMID 8314919 DOI: 10.1038/Jcbfm.1993.85  0.329
1993 Cumming P, Gjedde A. Kinetics of the uptake of [3H]paroxetine in the rat brain. Synapse (New York, N.Y.). 15: 124-9. PMID 8259523 DOI: 10.1002/Syn.890150204  0.385
1992 Cumming P, Vincent SR. Inhibition of histamine-N-methyltransferase (HNMT) by fragments of 9-amino-1,2,3,4-tetrahydroacridine (tacrine) and by beta-carbolines. Biochemical Pharmacology. 44: 989-92. PMID 1530666 DOI: 10.1016/0006-2952(92)90133-4  0.557
1992 Cumming P, Brown E, Damsma G, Fibiger H. Formation and clearance of interstitial metabolites of dopamine and serotonin in the rat striatum: an in vivo microdialysis study. Journal of Neurochemistry. 59: 1905-14. PMID 1383428 DOI: 10.1111/J.1471-4159.1992.Tb11026.X  0.344
1991 Cumming P, Damsma G, Fibiger HC, Vincent SR. Characterization of extracellular histamine in the striatum and bed nucleus of the stria terminalis of the rat: an in vivo microdialysis study. Journal of Neurochemistry. 56: 1797-803. PMID 1707442 DOI: 10.1111/J.1471-4159.1991.Tb02083.X  0.587
1991 Cumming P, Shaw C, Vincent SR. High affinity histamine binding site is the H3 receptor: characterization and autoradiographic localization in rat brain. Synapse (New York, N.Y.). 8: 144-51. PMID 1652795 DOI: 10.1002/Syn.890080208  0.586
1990 Cumming P, Reiner PB, Vincent SR. Inhibition of rat brain histamine-N-methyltransferase by 9-amino-1,2,3,4-tetrahydroacridine (THA). Biochemical Pharmacology. 40: 1345-50. PMID 2403387 DOI: 10.1016/0006-2952(90)90402-7  0.595
1990 Cumming P, Damsma G, Fibiger HC, Vincent SR. Determination of histamine in cerebral dialysates from the rat European Journal of Pharmacology. 183: 442. DOI: 10.1016/0014-2999(90)93329-O  0.542
1989 Cumming P, Jakubovic A, Vincent SR. Cerebral histamine levels are unaffected by MPTP administration in the mouse. European Journal of Pharmacology. 166: 299-301. PMID 2792195 DOI: 10.1016/0014-2999(89)90071-X  0.599
1988 Cumming P, Häusser M, Martin WR, Grierson J, Adam MJ, Ruth TJ, McGeer EG. Kinetics of in vitro decarboxylation and the in vivo metabolism of 2-18F- and 6-18F-fluorodopa in the hooded rat. Biochemical Pharmacology. 37: 247-50. PMID 3124856 DOI: 10.1016/0006-2952(88)90725-3  0.344
1987 Cumming P, Boyes BE, Martin WR, Adam M, Ruth TJ, McGeer EG. Altered metabolism of [18F]-6-fluorodopa in the hooded rat following inhibition of catechol-O-methyltransferase with U-0521. Biochemical Pharmacology. 36: 2527-31. PMID 3111485 DOI: 10.1016/0006-2952(87)90526-0  0.373
1987 Cumming P, Kamo H, McGeer EG, McGeer PL. Toxicity of p-methoxyphenol to dopamine neurons in the rat substantia nigra. Neuropharmacology. 26: 1795-7. PMID 2893988 DOI: 10.1016/0028-3908(87)90136-5  0.349
1987 Radke JM, Cumming P, Vincent SR. Effects of MPTP poisoning on central somatostatin and substance P levels in the mouse. European Journal of Pharmacology. 134: 105-8. PMID 2435563 DOI: 10.1016/0014-2999(87)90137-3  0.565
1986 Boyes BE, Cumming P, Martin WR, McGeer EG. Determination of plasma [18F]-6-fluorodopa during positron emission tomography: elimination and metabolism in carbidopa treated subjects. Life Sciences. 39: 2243-52. PMID 3097437 DOI: 10.1016/0024-3205(86)90403-0  0.327
1986 Cumming P, Von Krosigk M, Reiner PB, McGeer EG, Vincent SR. Absence of adrenaline neurons in the guinea pig brain: a combined immunohistochemical and high-performance liquid chromatography study. Neuroscience Letters. 63: 125-30. PMID 2869455 DOI: 10.1016/0304-3940(86)90048-0  0.569
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