George R. Jackson - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Drosophila

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Chouhan AK, Guo C, Hsieh YC, Ye H, Senturk M, Zuo Z, Li Y, Chatterjee S, Botas J, Jackson GR, Bellen HJ, Shulman JM. Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathologica Communications. 4: 62. PMID 27338814 DOI: 10.1186/s40478-016-0333-4  0.48
2016 Iyer J, Wang Q, Le T, Pizzo L, Grönke S, Ambegaokar S, Imai Y, Srivastava A, Llamusí Troisí B, Mardon G, Artero R, Jackson GR, Isaacs AM, Partridge L, Kumar JP, et al. Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster. G3 (Bethesda, Md.). PMID 26994292 DOI: 10.1534/g3.116.027060  0.96
2015 Sengupta U, Guerrero-Muñoz MJ, Castillo-Carranza DL, Lasagna-Reeves CA, Gerson JE, Paulucci-Holthauzen AA, Krishnamurthy S, Farhed M, Jackson GR, Kayed R. Pathological Interface between Oligomeric Alpha-Synuclein and Tau in Synucleinopathies. Biological Psychiatry. PMID 25676491 DOI: 10.1016/j.biopsych.2014.12.019  0.48
2014 Jackson GR. Learn to forget: regulation of age-related memory impairment by neuronal-glial crosstalk. Neuron. 84: 658-9. PMID 25459404 DOI: 10.1016/j.neuron.2014.11.001  0.96
2014 Guerrero-Muñoz MJ, Castillo-Carranza DL, Krishnamurthy S, Paulucci-Holthauzen AA, Sengupta U, Lasagna-Reeves CA, Ahmad Y, Jackson GR, Kayed R. Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease. Neurobiology of Disease. 71: 14-23. PMID 25134727 DOI: 10.1016/j.nbd.2014.08.008  0.48
2014 Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R. The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta Neuropathologica Communications. 2: 56. PMID 24887264 DOI: 10.1186/2051-5960-2-56  0.48
2014 Castillo-Carranza DL, Sengupta U, Guerrero-Muñoz MJ, Lasagna-Reeves CA, Gerson JE, Singh G, Estes DM, Barrett AD, Dineley KT, Jackson GR, Kayed R. Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4260-72. PMID 24647946 DOI: 10.1523/JNEUROSCI.3192-13.2014  0.48
2014 Bakhoum MF, Bakhoum CY, Ding Z, Carlton SM, Campbell GA, Jackson GR. Evidence for autophagic gridlock in aging and neurodegeneration. Translational Research : the Journal of Laboratory and Clinical Medicine. 164: 1-12. PMID 24561013 DOI: 10.1016/j.trsl.2014.01.016  0.96
2014 Roy B, Jackson GR. Interactions between Tau and α-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease. Human Molecular Genetics. 23: 3008-23. PMID 24430504 DOI: 10.1093/hmg/ddu011  0.96
2014 Choksi DK, Roy B, Chatterjee S, Yusuff T, Bakhoum MF, Sengupta U, Ambegaokar S, Kayed R, Jackson GR. TDP-43 Phosphorylation by casein kinase Iε promotes oligomerization and enhances toxicity in vivo. Human Molecular Genetics. 23: 1025-35. PMID 24105464 DOI: 10.1093/hmg/ddt498  0.96
2013 Wightman PJ, Jackson GR, Dipple KM. Disruption of glycerol metabolism by RNAi targeting of genes encoding glycerol kinase results in a range of phenotype severity in Drosophila. Plos One. 8: e71664. PMID 24039719 DOI: 10.1371/journal.pone.0071664  0.96
2013 Hawkins BE, Krishnamurthy S, Castillo-Carranza DL, Sengupta U, Prough DS, Jackson GR, DeWitt DS, Kayed R. Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies. The Journal of Biological Chemistry. 288: 17042-50. PMID 23632019 DOI: 10.1074/jbc.M113.472746  0.96
2013 Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, ... ... Jackson G, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/j.jalz.2012.03.003  0.96
2013 Roy B, Jackson GR. Neurodegenerationmodels in Drosophila Behavioral Genetics of the Fly (Drosophila Melanogaster). 135-161. DOI: 10.1017/CBO9780511920585.012  0.96
2012 Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V, Jackson GR, Kayed R. Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau. Scientific Reports. 2: 700. PMID 23050084 DOI: 10.1038/srep00700  0.96
2012 Ambegaokar SS, Jackson GR. The downward spiral of tau and autolysosomes: a new hypothesis in neurodegeneration. Autophagy. 8: 1144-5. PMID 22635052 DOI: 10.4161/auto.20515  0.96
2012 Wightman PJ, Jackson GR, Dipple KM. Glycerol hypersensitivity in a Drosophila model for glycerol kinase deficiency is affected by mutations in eye pigmentation genes. Plos One. 7: e31779. PMID 22427807 DOI: 10.1371/journal.pone.0031779  0.96
2012 Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Sarmiento J, Troncoso J, Jackson GR, Kayed R. Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1946-59. PMID 22253473 DOI: 10.1096/fj.11-199851  0.96
2011 Kayed R, Jackson GR, Estes DM, Barrett AD. Alzheimers disease: review of emerging treatment role for intravenous immunoglobulins. Journal of Central Nervous System Disease. 3: 67-73. PMID 23861639 DOI: 10.4137/JCNSD.S5018  0.48
2011 Ambegaokar SS, Jackson GR. Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. Human Molecular Genetics. 20: 4947-77. PMID 21949350 DOI: 10.1093/hmg/ddr432  0.96
2011 Clos AL, Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Jackson GR, Kelly B, Beachkofsky TM, Kayed R. Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis. The British Journal of Dermatology. 165: 1349-54. PMID 21729025 DOI: 10.1111/j.1365-2133.2011.10508.x  0.96
2011 Clos AL, Lasagna-Reeves CA, Kelly B, Wagner R, Wilkerson M, Jackson GR, Kayed R. Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis. Journal of the American Academy of Dermatology. 65: 1023-31. PMID 21669474 DOI: 10.1016/j.jaad.2010.09.735  0.96
2011 Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Clos AL, Jackson GR, Kayed R. Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Molecular Neurodegeneration. 6: 39. PMID 21645391 DOI: 10.1186/1750-1326-6-39  0.96
2011 Lasagna-Reeves CA, Castillo-Carranza DL, Jackson GR, Kayed R. Tau oligomers as potential targets for immunotherapy for Alzheimer's disease and tauopathies. Current Alzheimer Research. 8: 659-65. PMID 21605039 DOI: 10.2174/156720511796717177  0.96
2011 Ambegaokar SS, Jackson G. Double vision: pigment genes do more than just color. Fly. 5: 206-9. PMID 21406968  0.96
2011 Bakhoum MF, Jackson GR. Demise of the flies: why Drosophila models still matter. Progress in Molecular Biology and Translational Science. 100: 483-98. PMID 21377634 DOI: 10.1016/B978-0-12-384878-9.00011-X  0.96
2011 Chang YC, Hung WT, Chang YC, Chang HC, Wu CL, Chiang AS, Jackson GR, Sang TK. Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model. Plos Genetics. 7: e1001288. PMID 21304887 DOI: 10.1371/journal.pgen.1001288  0.96
2011 Ambegaokar SS, Jackson GR. Double vision-pigment genes do more than just color Fly. 5: 1-4. DOI: 10.1534/genetics.110.119545.  0.96
2010 Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Muoz MJ, Jackson GR, Kayed R. Preparation and characterization of neurotoxic tau oligomers. Biochemistry. 49: 10039-41. PMID 21047142 DOI: 10.1021/bi1016233  0.96
2010 Lasagna-Reeves CA, Clos AL, Midoro-Hiriuti T, Goldblum RM, Jackson GR, Kayed R. Inhaled insulin forms toxic pulmonary amyloid aggregates. Endocrinology. 151: 4717-24. PMID 20685871 DOI: 10.1210/en.2010-0457  0.96
2010 Clos AL, Lasagna-Reeves CA, Wagner R, Kelly B, Jackson GR, Kayed R. Therapeutic removal of amyloid deposits in cutaneous amyloidosis by localised intra-lesional injections of anti-amyloid antibodies. Experimental Dermatology. 19: 904-11. PMID 20626464 DOI: 10.1111/j.1600-0625.2010.01121.x  0.96
2010 Ambegaokar SS, Jackson GR. Interaction between eye pigment genes and tau-induced neurodegeneration in Drosophila melanogaster. Genetics. 186: 435-42. PMID 20592261 DOI: 10.1534/genetics.110.119545  0.96
2010 Ambegaokar SS, Roy B, Jackson GR. Neurodegenerative models in Drosophila: polyglutamine disorders, Parkinson disease, and amyotrophic lateral sclerosis. Neurobiology of Disease. 40: 29-39. PMID 20561920 DOI: 10.1016/j.nbd.2010.05.026  0.96
2010 Barrett AD, Kayed R, Jackson GR, Cunningham KA. New vaccine development for chronic brain disease. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 354. PMID 20010720 DOI: 10.1038/npp.2009.147  0.96
2009 Kuo SH, Jackson GR. Emerging subspecialties in neurology: translational research in movement disorders. Neurology. 73: e40-1. PMID 19704074 DOI: 10.1212/WNL.0b013e3181b388b6  0.96
2009 Kayed R, Jackson GR. Prefilament tau species as potential targets for immunotherapy for Alzheimer disease and related disorders. Current Opinion in Immunology. 21: 359-63. PMID 19482462 DOI: 10.1016/j.coi.2009.05.001  0.96
2009 Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1962-76. PMID 19228951 DOI: 10.1523/JNEUROSCI.5351-08.2009  0.96
2009 Chatterjee S, Sang TK, Lawless GM, Jackson GR. Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model. Human Molecular Genetics. 18: 164-77. PMID 18930955 DOI: 10.1093/hmg/ddn326  0.96
2008 Schaffer BA, Bertram L, Miller BL, Mullin K, Weintraub S, Johnson N, Bigio EH, Mesulam M, Wiedau-Pazos M, Jackson GR, Cummings JL, Cantor RM, Levey AI, Tanzi RE, Geschwind DH. Association of GSK3B with Alzheimer disease and frontotemporal dementia. Archives of Neurology. 65: 1368-74. PMID 18852354 DOI: 10.1001/archneur.65.10.1368  0.96
2008 Ratnaparkhi A, Lawless GM, Schweizer FE, Golshani P, Jackson GR. A Drosophila model of ALS: human ALS-associated mutation in VAP33A suggests a dominant negative mechanism. Plos One. 3: e2334. PMID 18523548 DOI: 10.1371/journal.pone.0002334  0.96
2008 Jackson GR. Guide to understanding Drosophila models of neurodegenerative diseases. Plos Biology. 6: e53. PMID 18303955 DOI: 10.1371/journal.pbio.0060053  0.96
2007 Dotti CG, Feiguin F, Fortini ME. gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo. Neuron. 53: 463. PMID 17326324 DOI: 10.1016/j.neuron.2007.01.012  0.96
2007 Sang TK, Chang HY, Lawless GM, Ratnaparkhi A, Mee L, Ackerson LC, Maidment NT, Krantz DE, Jackson GR. A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 981-92. PMID 17267552 DOI: 10.1523/JNEUROSCI.4810-06.2007  0.96
2006 Sengupta S, Horowitz PM, Karsten SL, Jackson GR, Geschwind DH, Fu Y, Berry RW, Binder LI. Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry. 45: 15111-9. PMID 17154549 DOI: 10.1021/bi061830d  0.96
2006 Slepko N, Bhattacharyya AM, Jackson GR, Steffan JS, Marsh JL, Thompson LM, Wetzel R. Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins. Proceedings of the National Academy of Sciences of the United States of America. 103: 14367-72. PMID 16980414 DOI: 10.1073/pnas.0602348103  0.96
2006 Karsten SL, Sang TK, Gehman LT, Chatterjee S, Liu J, Lawless GM, Sengupta S, Berry RW, Pomakian J, Oh HS, Schulz C, Hui KS, Wiedau-Pazos M, Vinters HV, Binder LI, ... ... Jackson GR, et al. A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron. 51: 549-60. PMID 16950154 DOI: 10.1016/j.neuron.2006.07.019  0.96
2006 Doglio LE, Kanwar R, Jackson GR, Perez M, Avila J, Dingwall C, Dotti CG, Fortini ME, Feiguin F. gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo. Neuron. 50: 359-75. PMID 16675392 DOI: 10.1016/j.neuron.2006.03.038  0.96
2006 Fogel B, Wu M, Kremen S, Murthy K, Jackson G, Vanek Z. Creutzfeldt-Jakob disease presenting with alien limb sign. Movement Disorders : Official Journal of the Movement Disorder Society. 21: 1040-2. PMID 16552737 DOI: 10.1002/mds.20858  0.96
2006 Jackson GR, Sang TK, Paul Taylor J. Drosophila models of polyglutamine disorders Genetic Instabilities and Neurological Diseases, Second Edition. 587-594. DOI: 10.1016/B978-012369462-1/50038-7  0.96
2005 Sang TK, Jackson GR. Drosophila models of neurodegenerative disease. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 2: 438-46. PMID 16389307 DOI: 10.1602/neurorx.2.3.438  0.96
2005 Mee L, Honkala H, Kopra O, Vesa J, Finnilä S, Visapää I, Sang TK, Jackson GR, Salonen R, Kestilä M, Peltonen L. Hydrolethalus syndrome is caused by a missense mutation in a novel gene HYLS1. Human Molecular Genetics. 14: 1475-88. PMID 15843405 DOI: 10.1093/hmg/ddi157  0.96
2005 Sang TK, Li C, Liu W, Rodriguez A, Abrams JM, Zipursky SL, Jackson GR. Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis. Human Molecular Genetics. 14: 357-72. PMID 15590702 DOI: 10.1093/hmg/ddi032  0.96
2005 Hogarth P, Kayson E, Kieburtz K, Marder K, Oakes D, Rosas D, Shoulson I, Wexler NS, Young AB, Zhao H. Interrater agreement in the assessment of motor manifestations of Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 293-7. PMID 15584032 DOI: 10.1002/mds.20332  0.96
2002 Jackson GR, Wiedau-Pazos M, Sang TK, Wagle N, Brown CA, Massachi S, Geschwind DH. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron. 34: 509-19. PMID 12062036 DOI: 10.1016/S0896-6273(02)00706-7  0.96
2001 Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature. 413: 739-43. PMID 11607033 DOI: 10.1038/35099568  0.96
1998 Jackson GR, Salecker I, Dong X, Yao X, Arnheim N, Faber PW, MacDonald ME, Zipursky SL. Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron. 21: 633-42. PMID 9768849 DOI: 10.1016/S0896-6273(00)80573-5  0.96
1997 Pan Z, Sampath D, Jackson G, Werrbach-Perez K, Perez-Polo R. Nerve growth factor and oxidative stress in the nervous system. Advances in Experimental Medicine and Biology. 429: 173-93. PMID 9413574  0.96
1996 Jackson GR, Perez-Polo JR. [1] Paradigms for study of neurotrophin effects in oxidant injury Methods in Neurosciences. 30: 1-25. DOI: 10.1016/S1043-9471(96)80093-0  0.96
1994 Sampath D, Jackson GR, Werrbach-Perez K, Perez-Polo JR. Effects of nerve growth factor on glutathione peroxidase and catalase in PC12 cells. Journal of Neurochemistry. 62: 2476-9. PMID 8189251  0.96
1994 Jackson GR, Sampath D, Werrbach-Perez K, Perez-Polo JR. Effects of nerve growth factor on catalase and glutathione peroxidase in a hydrogen peroxide-resistant pheochromocytoma subclone. Brain Research. 634: 69-76. PMID 8156393 DOI: 10.1016/0006-8993(94)90259-3  0.96
1994 Jackson GR, Werrbach-Perez K, Pan Z, Sampath D, Perez-Polo JR. Neurotrophin regulation of energy homeostasis in the central nervous system. Developmental Neuroscience. 16: 285-90. PMID 7768207 DOI: 10.1159/000112121  0.96
1992 Jackson GR, Werrbach-Perez K, Ezell EL, Post JF, Perez-Polo JR. Nerve growth factor effects on pyridine nucleotides after oxidant injury of rat pheochromocytoma cells. Brain Research. 592: 239-48. PMID 1450913 DOI: 10.1016/0006-8993(92)91681-4  0.96
1992 Taglialatela G, Angelucci L, Ramacci MT, Werrbach-Perez K, Jackson GR, Perez-Polo JR. Stimulation of nerve growth factor receptors in PC12 by acetyl-L-carnitine. Biochemical Pharmacology. 44: 577-85. PMID 1324679 DOI: 10.1016/0006-2952(92)90452-O  0.96
1992 Foreman PJ, Taglialatela G, Jackson GR, Perez-Polo JR. Dexamethasone blocks nerve growth factor induction of nerve growth factor receptor mRNA in PC12 cells. Journal of Neuroscience Research. 31: 52-7. PMID 1319504 DOI: 10.1002/jnr.490310108  0.96
1991 Taglialatela G, Angelucci L, Ramacci MT, Werrbach-Perez K, Jackson GR, Perez-Polo JR. Acetyl-L-carnitine enhances the response of PC12 cells to nerve growth factor. Brain Research. Developmental Brain Research. 59: 221-30. PMID 1655307 DOI: 10.1016/0165-3806(91)90102-O  0.96
1991 Jackson GR, Morgan BC, Werrbach-Perez K, Perez-Polo JR. Antioxidant effect of retinoic acid on PC12 rat pheochromocytoma. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 9: 161-70. PMID 1647645 DOI: 10.1016/0736-5748(91)90007-9  0.96
1990 Jackson GR, Werrbach-Perez K, Perez-Polo JR. Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. II. A conditioning lesion paradigm. Journal of Neuroscience Research. 25: 369-74. PMID 2325162 DOI: 10.1002/jnr.490250314  0.96
1990 Jackson GR, Apffel L, Werrbach-Perez K, Perez-Polo JR. Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance. Journal of Neuroscience Research. 25: 360-8. PMID 2325161 DOI: 10.1002/jnr.490250313  0.96
1990 Perez-Polo JR, Foreman PJ, Jackson GR, Shan D, Taglialatela G, Thorpe LW, Werrbach-Perez K. Nerve growth factor and neuronal cell death. Molecular Neurobiology. 4: 57-91. PMID 2076219 DOI: 10.1007/BF02935585  0.96
1990 Werrbach-Perez K, Jackson G, Marchetti D, Morgan B, Thorpe L, Perez-Polo JR. Growth factor-mediated protection in aging CNS. Progress in Brain Research. 86: 183-94. PMID 1965052  0.96
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