Shigeyoshi Itohara - Publications

RIKEN Brain Science Institute, Wakō-shi, Saitama-ken, Japan 

262 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ajima A, Yoshida T, Yaguchi K, Itohara S. Objective detection of microtremors in netrin-G2 knockout mice. Journal of Neuroscience Methods. 351: 109074. PMID 33450333 DOI: 10.1016/j.jneumeth.2021.109074  0.32
2020 Abe K, Kuroda M, Narumi Y, Kobayashi Y, Itohara S, Furuichi T, Sano Y. Cortico-amygdala interaction determines the insular cortical neurons involved in taste memory retrieval. Molecular Brain. 13: 107. PMID 32723372 DOI: 10.1186/s13041-020-00646-w  0.72
2020 Shibano N, Yamazaki M, Arima T, Abe K, Kuroda M, Kobayashi Y, Itohara S, Furuichi T, Sano Y. Excitation of prefrontal cortical neurons during conditioning enhances fear memory formation. Scientific Reports. 10: 8613. PMID 32451463 DOI: 10.1038/s41598-020-65597-7  0.72
2020 Masuda A, Sano C, Zhang Q, Goto H, McHugh TJ, Fujisawa S, Itohara S. The hippocampus encodes delay and value information during delay-discounting decision making. Elife. 9. PMID 32077851 DOI: 10.7554/eLife.52466  0.32
2020 Kashiwagi M, Kanuka M, Tatsuzawa C, Suzuki H, Morita M, Tanaka K, Kawano T, Shin JW, Suzuki H, Itohara S, Yanagisawa M, Hayashi Y. Widely Distributed Neurotensinergic Neurons in the Brainstem Regulate NREM Sleep in Mice. Current Biology : Cb. PMID 32032507 DOI: 10.1016/j.cub.2020.01.047  0.48
2019 Miyamoto H, Tatsukawa T, Shimohata A, Yamagata T, Suzuki T, Amano K, Mazaki E, Raveau M, Ogiwara I, Oba-Asaka A, Hensch TK, Itohara S, Sakimura K, Kobayashi K, Kobayashi K, et al. Impaired cortico-striatal excitatory transmission triggers epilepsy. Nature Communications. 10: 1917. PMID 31015467 DOI: 10.1038/s41467-019-09954-9  0.48
2018 Kato TM, Kubota-Sakashita M, Fujimori-Tonou N, Saitow F, Fuke S, Masuda A, Itohara S, Suzuki H, Kato T. Mitochondrial dysfunction causes hyperexcitability of serotonergic neurons. Molecular Psychiatry. 23: 1971. PMID 30467341 DOI: 10.1038/s41380-018-0295-y  0.48
2018 Zhang Q, Kobayashi Y, Goto H, Itohara S. An Automated T-maze Based Apparatus and Protocol for Analyzing Delay- and Effort-based Decision Making in Free Moving Rodents. Journal of Visualized Experiments : Jove. PMID 30124665 DOI: 10.3791/57895  0.72
2018 Masuda A, Kobayashi Y, Itohara S. Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage. Journal of Visualized Experiments : Jove. PMID 30124661 DOI: 10.3791/58009  0.72
2018 Kato TM, Kubota-Sakashita M, Fujimori-Tonou N, Saitow F, Fuke S, Masuda A, Itohara S, Suzuki H, Kato T. Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder. Molecular Psychiatry. PMID 29892051 DOI: 10.1038/s41380-018-0074-9  0.48
2017 Miyamoto H, Shimohata A, Abe M, Abe T, Mazaki E, Amano K, Suzuki T, Tatsukawa T, Itohara S, Sakimura K, Yamakawa K. Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbp1 haploinsufficiency. Human Molecular Genetics. PMID 29040524 DOI: 10.1093/hmg/ddx379  0.48
2017 Shiihashi G, Ito D, Arai I, Kobayashi Y, Hayashi K, Otsuka S, Nakajima K, Yuzaki M, Itohara S, Suzuki N. Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma. Ebiomedicine. PMID 28928015 DOI: 10.1016/j.ebiom.2017.09.005  0.72
2016 Yoshikawa F, Sato Y, Tohyama K, Akagi T, Furuse T, Sadakata T, Tanaka M, Shinoda Y, Hashikawa T, Itohara S, Sano Y, Ghandour MS, Wakana S, Furuichi T. Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments. Plos One. 11: e0166732. PMID 27855200 DOI: 10.1371/journal.pone.0166732  0.72
2016 Kim J, Pignatelli M, Xu S, Itohara S, Tonegawa S. Antagonistic negative and positive neurons of the basolateral amygdala. Nature Neuroscience. PMID 27749826 DOI: 10.1038/nn.4414  1
2016 Okuyama T, Kitamura T, Roy DS, Itohara S, Tonegawa S. Ventral CA1 neurons store social memory. Science (New York, N.Y.). 353: 1536-1541. PMID 27708103 DOI: 10.1126/science.aaf7003  1
2016 Shinoda Y, Ishii C, Fukazawa Y, Sadakata T, Ishii Y, Sano Y, Iwasato T, Itohara S, Furuichi T. CAPS1 stabilizes the state of readily releasable synaptic vesicles to fusion competence at CA3-CA1 synapses in adult hippocampus. Scientific Reports. 6: 31540. PMID 27545744 DOI: 10.1038/srep31540  1
2016 Masuda A, Kobayashi Y, Kogo N, Saito T, Saido TC, Itohara S. Cognitive deficits in single App knock-in mouse models. Neurobiology of Learning and Memory. PMID 27377630 DOI: 10.1016/j.nlm.2016.07.001  0.72
2016 Zhang Q, Sano C, Masuda A, Ando R, Tanaka M, Itohara S. Netrin-G1 regulates fear-like and anxiety-like behaviors in dissociable neural circuits. Scientific Reports. 6: 28750. PMID 27345935 DOI: 10.1038/srep28750  1
2016 Monai H, Ohkura M, Tanaka M, Oe Y, Konno A, Hirai H, Mikoshiba K, Itohara S, Nakai J, Iwai Y, Hirase H. Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain. Nature Communications. 7: 11100. PMID 27000523 DOI: 10.1038/ncomms11100  1
2016 Zhang Q, Gao X, Li C, Feliciano C, Wang D, Zhou D, Mei Y, Monteiro P, Anand M, Itohara S, Dong X, Fu Z, Feng G. Impaired Dendritic Development and Memory in Sorbs2 Knock-Out Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 2247-60. PMID 26888934 DOI: 10.1523/JNEUROSCI.2528-15.2016  1
2016 Zhang Q, Goto H, Akiyoshi-Nishimura S, Prosselkov P, Sano C, Matsukawa H, Yaguchi K, Nakashiba T, Itohara S. Diversification of behavior and postsynaptic properties by netrin-G presynaptic adhesion family proteins. Molecular Brain. 9: 6. PMID 26746425 DOI: 10.1186/s13041-016-0187-5  1
2015 Hayashi Y, Kashiwagi M, Yasuda K, Ando R, Kanuka M, Sakai K, Itohara S. Cells of a common developmental origin regulate REM/non-REM sleep and wakefulness in mice. Science (New York, N.Y.). PMID 26494173 DOI: 10.1126/science.aad1023  1
2015 Iwata R, Matsukawa H, Yasuda K, Mizuno H, Itohara S, Iwasato T. Developmental RacGAP α2-Chimaerin Signaling Is a Determinant of the Morphological Features of Dendritic Spines in Adulthood. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13728-44. PMID 26446225 DOI: 10.1523/JNEUROSCI.0419-15.2015  1
2015 Sato T, Kobayakawa R, Kobayakawa K, Emura M, Itohara S, Kizumi M, Hamana H, Tsuboi A, Hirono J. Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding. Scientific Reports. 5: 14073. PMID 26361056 DOI: 10.1038/srep14073  1
2015 Niven J, Hoare J, McGowan D, Devarajan G, Itohara S, Gannagé M, Teismann P, Crane I. S100B Up-Regulates Macrophage Production of IL1β and CCL22 and Influences Severity of Retinal Inflammation. Plos One. 10: e0132688. PMID 26204512 DOI: 10.1371/journal.pone.0132688  1
2015 Lee K, Kobayashi Y, Seo H, Kwak JH, Masuda A, Lim CS, Lee HR, Kang SJ, Park P, Sim SE, Kogo N, Kawasaki H, Kaang BK, Itohara S. Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility. Molecular Brain. 8: 38. PMID 26104314 DOI: 10.1186/s13041-015-0130-1  1
2015 Takahashi A, Lee RX, Iwasato T, Itohara S, Arima H, Bettler B, Miczek KA, Koide T. Glutamate input in the dorsal raphe nucleus as a determinant of escalated aggression in male mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6452-63. PMID 25904796 DOI: 10.1523/JNEUROSCI.2450-14.2015  1
2015 Suzuki A, Lee LJ, Hayashi Y, Muglia L, Itohara S, Erzurumlu RS, Iwasato T. Thalamic adenylyl cyclase 1 is required for barrel formation in the somatosensory cortex. Neuroscience. 290: 518-29. PMID 25644422 DOI: 10.1016/j.neuroscience.2015.01.043  1
2015 Itohara S, Kobayashi Y, Nakashiba T. Genetic factors underlying attention and impulsivity: Mouse models of attention-deficit/hyperactivity disorder Current Opinion in Behavioral Sciences. 2: 46-51. DOI: 10.1016/j.cobeha.2014.09.002  1
2014 Matsukawa H, Akiyoshi-Nishimura S, Zhang Q, Luján R, Yamaguchi K, Goto H, Yaguchi K, Hashikawa T, Sano C, Shigemoto R, Nakashiba T, Itohara S. Netrin-G/NGL complexes encode functional synaptic diversification. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15779-92. PMID 25411505 DOI: 10.1523/JNEUROSCI.1141-14.2014  1
2014 Mishiba T, Tanaka M, Mita N, He X, Sasamoto K, Itohara S, Ohshima T. Cdk5/p35 functions as a crucial regulator of spatial learning and memory. Molecular Brain. 7: 82. PMID 25404232 DOI: 10.1186/s13041-014-0082-x  1
2014 Arakawa H, Suzuki A, Zhao S, Tsytsarev V, Lo FS, Hayashi Y, Itohara S, Iwasato T, Erzurumlu RS. Thalamic NMDA receptor function is necessary for patterning of the thalamocortical somatosensory map and for sensorimotor behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12001-14. PMID 25186746 DOI: 10.1523/JNEUROSCI.1663-14.2014  1
2014 Iwata R, Ohi K, Kobayashi Y, Masuda A, Iwama M, Yasuda Y, Yamamori H, Tanaka M, Hashimoto R, Itohara S, Iwasato T. RacGAP α2-chimaerin function in development adjusts cognitive ability in adulthood. Cell Reports. 8: 1257-64. PMID 25159148 DOI: 10.1016/j.celrep.2014.07.047  1
2014 Srimontri P, Endo S, Sakamoto T, Nakayama Y, Kurosaka A, Itohara S, Hirabayashi Y, Kato K. Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy. Journal of Neurochemistry. 131: 675-87. PMID 25066807 DOI: 10.1111/jnc.12838  1
2014 Kawase S, Kuwako K, Imai T, Renault-Mihara F, Yaguchi K, Itohara S, Okano H. Regulatory factor X transcription factors control Musashi1 transcription in mouse neural stem/progenitor cells. Stem Cells and Development. 23: 2250-61. PMID 25058468 DOI: 10.1089/scd.2014.0219  1
2014 Onodera T, Sakudo A, Tsubone H, Itohara S. Review of studies that have used knockout mice to assess normal function of prion protein under immunological or pathophysiological stress. Microbiology and Immunology. 58: 361-74. PMID 24866463 DOI: 10.1111/1348-0421.12162  1
2014 Ono K, Clavairoly A, Nomura T, Gotoh H, Uno A, Armant O, Takebayashi H, Zhang Q, Shimamura K, Itohara S, Parras CM, Ikenaka K. Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2. Development (Cambridge, England). 141: 2075-84. PMID 24803655 DOI: 10.1242/dev.097790  1
2014 Saito T, Matsuba Y, Mihira N, Takano J, Nilsson P, Itohara S, Iwata N, Saido TC. Single App knock-in mouse models of Alzheimer's disease. Nature Neuroscience. 17: 661-3. PMID 24728269 DOI: 10.1038/nn.3697  1
2014 Mizuno H, Luo W, Tarusawa E, Saito YM, Sato T, Yoshimura Y, Itohara S, Iwasato T. NMDAR-regulated dynamics of layer 4 neuronal dendrites during thalamocortical reorganization in neonates. Neuron. 82: 365-79. PMID 24685175 DOI: 10.1016/j.neuron.2014.02.026  1
2014 Yaguchi K, Nishimura-Akiyoshi S, Kuroki S, Onodera T, Itohara S. Identification of transcriptional regulatory elements for Ntng1 and Ntng2 genes in mice. Molecular Brain. 7: 19. PMID 24642214 DOI: 10.1186/1756-6606-7-19  1
2014 Borgius L, Nishimaru H, Caldeira V, Kunugise Y, Löw P, Reig R, Itohara S, Iwasato T, Kiehn O. Spinal glutamatergic neurons defined by EphA4 signaling are essential components of normal locomotor circuits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3841-53. PMID 24623763 DOI: 10.1523/JNEUROSCI.4992-13.2014  1
2014 Wu YW, Tang X, Arizono M, Bannai H, Shih PY, Dembitskaya Y, Kazantsev V, Tanaka M, Itohara S, Mikoshiba K, Semyanov A. Spatiotemporal calcium dynamics in single astrocytes and its modulation by neuronal activity. Cell Calcium. 55: 119-29. PMID 24484772 DOI: 10.1016/j.ceca.2013.12.006  1
2014 Kondo T, Isono K, Kondo K, Endo TA, Itohara S, Vidal M, Koseki H. Polycomb potentiates meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer. Developmental Cell. 28: 94-101. PMID 24374176 DOI: 10.1016/j.devcel.2013.11.021  1
2013 Sadakata T, Kakegawa W, Shinoda Y, Hosono M, Katoh-Semba R, Sekine Y, Sato Y, Tanaka M, Iwasato T, Itohara S, Furuyama K, Kawaguchi Y, Ishizaki Y, Yuzaki M, Furuichi T. CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17326-34. PMID 24174665 DOI: 10.1523/JNEUROSCI.2777-13.2013  1
2013 Matsuyama M, Tanaka H, Inoko A, Goto H, Yonemura S, Kobori K, Hayashi Y, Kondo E, Itohara S, Izawa I, Inagaki M. Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells. The Journal of Biological Chemistry. 288: 35626-35. PMID 24142690 DOI: 10.1074/jbc.M113.514737  1
2013 Ushiki-Kaku Y, Iwamaru Y, Masujin K, Imamura M, Itohara S, Ogawa-Goto K, Hattori S, Yokoyama T. Different antigenicities of the N-terminal region of cellular and scrapie prion proteins. Microbiology and Immunology. 57: 792-6. PMID 24117858 DOI: 10.1111/1348-0421.12105  1
2013 Song YS, Lee HJ, Prosselkov P, Itohara S, Kim E. Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses. Journal of Cell Science. 126: 4926-38. PMID 23986473 DOI: 10.1242/jcs.129718  1
2013 Ogiwara I, Iwasato T, Miyamoto H, Iwata R, Yamagata T, Mazaki E, Yanagawa Y, Tamamaki N, Hensch TK, Itohara S, Yamakawa K. Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome. Human Molecular Genetics. 22: 4784-804. PMID 23922229 DOI: 10.1093/hmg/ddt331  1
2013 Hägglund M, Dougherty KJ, Borgius L, Itohara S, Iwasato T, Kiehn O. Optogenetic dissection reveals multiple rhythmogenic modules underlying locomotion. Proceedings of the National Academy of Sciences of the United States of America. 110: 11589-94. PMID 23798384 DOI: 10.1073/pnas.1304365110  1
2013 Sassa T, Ohno Y, Suzuki S, Nomura T, Nishioka C, Kashiwagi T, Hirayama T, Akiyama M, Taguchi R, Shimizu H, Itohara S, Kihara A. Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production. Molecular and Cellular Biology. 33: 2787-96. PMID 23689133 DOI: 10.1128/MCB.00192-13  1
2013 Kobayashi Y, Sano Y, Vannoni E, Goto H, Suzuki H, Oba A, Kawasaki H, Kanba S, Lipp HP, Murphy NP, Wolfer DP, Itohara S. Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice. Frontiers in Behavioral Neuroscience. 7: 17. PMID 23487260 DOI: 10.3389/fnbeh.2013.00017  1
2013 Tanaka M, Shih PY, Gomi H, Yoshida T, Nakai J, Ando R, Furuichi T, Mikoshiba K, Semyanov A, Itohara S. Astrocytic Ca2+ signals are required for the functional integrity of tripartite synapses. Molecular Brain. 6: 6. PMID 23356992 DOI: 10.1186/1756-6606-6-6  1
2013 Ninomiya S, Esumi S, Ohta K, Fukuda T, Ito T, Imayoshi I, Kageyama R, Ikeda T, Itohara S, Tamamaki N. Amygdala kindling induces nestin expression in the leptomeninges of the neocortex. Neuroscience Research. 75: 121-9. PMID 23305954 DOI: 10.1016/j.neures.2012.12.006  1
2012 Sadakata T, Shinoda Y, Oka M, Sekine Y, Sato Y, Saruta C, Miwa H, Tanaka M, Itohara S, Furuichi T. Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 21104-9. PMID 23213205 DOI: 10.1073/pnas.1210055109  1
2012 Sathe K, Maetzler W, Lang JD, Mounsey RB, Fleckenstein C, Martin HL, Schulte C, Mustafa S, Synofzik M, Vukovic Z, Itohara S, Berg D, Teismann P. S100B is increased in Parkinson's disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway. Brain : a Journal of Neurology. 135: 3336-47. PMID 23169921 DOI: 10.1093/brain/aws250  1
2012 Yamashita H, Chen S, Komagata S, Hishida R, Iwasato T, Itohara S, Yagi T, Endo N, Shibata M, Shibuki K. Restoration of contralateral representation in the mouse somatosensory cortex after crossing nerve transfer. Plos One. 7: e35676. PMID 22536423 DOI: 10.1371/journal.pone.0035676  1
2012 Dhande OS, Bhatt S, Anishchenko A, Elstrott J, Iwasato T, Swindell EC, Xu HP, Jamrich M, Itohara S, Feller MB, Crair MC. Role of adenylate cyclase 1 in retinofugal map development. The Journal of Comparative Neurology. 520: 1562-83. PMID 22102330 DOI: 10.1002/cne.23000  1
2011 Mizoguchi H, Nakade J, Tachibana M, Ibi D, Someya E, Koike H, Kamei H, Nabeshima T, Itohara S, Takuma K, Sawada M, Sato J, Yamada K. Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 12963-71. PMID 21900575 DOI: 10.1523/JNEUROSCI.3118-11.2011  1
2011 Szabadits E, Cserép C, Szonyi A, Fukazawa Y, Shigemoto R, Watanabe M, Itohara S, Freund TF, Nyiri G. NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5893-904. PMID 21508214 DOI: 10.1523/JNEUROSCI.5938-10.2011  1
2011 Kawase S, Imai T, Miyauchi-Hara C, Yaguchi K, Nishimoto Y, Fukami S, Matsuzaki Y, Miyawaki A, Itohara S, Okano H. Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/progenitor cells. Molecular Brain. 4: 14. PMID 21486496 DOI: 10.1186/1756-6606-4-14  1
2011 Kim HS, Seto-Ohshima A, Nishiyama H, Itohara S. Normal delay eyeblink conditioning in mice devoid of astrocytic S100B. Neuroscience Letters. 489: 148-53. PMID 21146588 DOI: 10.1016/j.neulet.2010.12.005  1
2010 Ano Y, Sakudo A, Uraki R, Sato Y, Kono J, Sugiura K, Yokoyama T, Itohara S, Nakayama H, Yukawa M, Onodera T. Enhanced enteric invasion of scrapie agents into the villous columnar epithelium via maternal immunoglobulin. International Journal of Molecular Medicine. 26: 845-51. PMID 21042778 DOI: 10.3892/ijmm-00000533  1
2010 Yang JH, Wada A, Yoshida K, Miyoshi Y, Sayano T, Esaki K, Kinoshita MO, Tomonaga S, Azuma N, Watanabe M, Hamase K, Zaitsu K, Machida T, Messing A, Itohara S, et al. Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain. The Journal of Biological Chemistry. 285: 41380-90. PMID 20966073 DOI: 10.1074/jbc.M110.187443  1
2010 Gomi H, Sassa T, Thompson RF, Itohara S. Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice. Frontiers in Behavioral Neuroscience. 4: 17. PMID 20428496 DOI: 10.3389/fnbeh.2010.00017  1
2010 Hirai A, Ohtsuka N, Ikeda T, Taniguchi R, Blau D, Nakagaki K, Miura HS, Ami Y, Yamada YK, Itohara S, Holmes KV, Taguchi F. Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b. Journal of Virology. 84: 6654-66. PMID 20410265 DOI: 10.1128/JVI.02680-09  1
2010 Ushiki-Kaku Y, Endo R, Iwamaru Y, Shimizu Y, Imamura M, Masujin K, Yamamoto T, Hattori S, Itohara S, Irie S, Yokoyama T. Tracing conformational transition of abnormal prion proteins during interspecies transmission by using novel antibodies. The Journal of Biological Chemistry. 285: 11931-6. PMID 20177064 DOI: 10.1074/jbc.M109.058859  1
2010 Tanabe Y, Hirano A, Iwasato T, Itohara S, Araki K, Yamaguchi T, Ichikawa T, Kumanishi T, Aizawa Y, Takahashi H, Kakita A, Nawa H. Molecular characterization and gene disruption of a novel zinc-finger protein, HIT-4, expressed in rodent brain. Journal of Neurochemistry. 112: 1035-44. PMID 19968752 DOI: 10.1111/j.1471-4159.2009.06525.x  1
2010 Gomi H, Yokoyama T, Itohara S. Role of GFAP in morphological retention and distribution of reactive astrocytes induced by scrapie encephalopathy in mice. Brain Research. 1312: 156-67. PMID 19931516 DOI: 10.1016/j.brainres.2009.11.025  1
2010 Kojima N, Hanamura K, Yamazaki H, Ikeda T, Itohara S, Shirao T. Genetic disruption of the alternative splicing of drebrin gene impairs context-dependent fear learning in adulthood. Neuroscience. 165: 138-50. PMID 19837137 DOI: 10.1016/j.neuroscience.2009.10.016  1
2009 Sano Y, Ornthanalai VG, Yamada K, Homma C, Suzuki H, Suzuki T, Murphy NP, Itohara S. X11-like protein deficiency is associated with impaired conflict resolution in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5884-96. PMID 19420255 DOI: 10.1523/JNEUROSCI.5756-08.2009  1
2009 Singer P, Yee BK, Feldon J, Iwasato T, Itohara S, Grampp T, Prenosil G, Benke D, Möhler H, Boison D. Altered mnemonic functions and resistance to N-METHYL-d-Aspartate receptor antagonism by forebrain conditional knockout of glycine transporter 1. Neuroscience. 161: 635-54. PMID 19332109 DOI: 10.1016/j.neuroscience.2009.03.056  1
2009 Amano K, Fujii M, Arata S, Tojima T, Ogawa M, Morita N, Shimohata A, Furuichi T, Itohara S, Kamiguchi H, Korenberg JR, Arata A, Yamakawa K. DSCAM deficiency causes loss of pre-inspiratory neuron synchroneity and perinatal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2984-96. PMID 19261893 DOI: 10.1523/JNEUROSCI.3624-08.2009  1
2009 Endo S, Shutoh F, Dinh TL, Okamoto T, Ikeda T, Suzuki M, Kawahara S, Yanagihara D, Sato Y, Yamada K, Sakamoto T, Kirino Y, Hartell NA, Yamaguchi K, Itohara S, et al. Dual involvement of G-substrate in motor learning revealed by gene deletion. Proceedings of the National Academy of Sciences of the United States of America. 106: 3525-30. PMID 19218432 DOI: 10.1073/pnas.0813341106  1
2009 Suzuki T, Miyamoto H, Nakahari T, Inoue I, Suemoto T, Jiang B, Hirota Y, Itohara S, Saido TC, Tsumoto T, Sawamoto K, Hensch TK, Delgado-Escueta AV, Yamakawa K. Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility. Human Molecular Genetics. 18: 1099-109. PMID 19147686 DOI: 10.1093/hmg/ddp006  1
2009 Kishioka A, Fukushima F, Ito T, Kataoka H, Mori H, Ikeda T, Itohara S, Sakimura K, Mishina M. A novel form of memory for auditory fear conditioning at a low-intensity unconditioned stimulus. Plos One. 4: e4157. PMID 19132103 DOI: 10.1371/journal.pone.0004157  1
2009 Ano Y, Nakayama H, Sakudo A, Sawano Y, Tanokura M, Itohara S, Onodera T. Intestinal uptake of amyloid beta protein through columnar epithelial cells in suckling mice. Histology and Histopathology. 24: 283-92. PMID 19130397  1
2008 Tanaka M, Yamaguchi K, Tatsukawa T, Nishioka C, Nishiyama H, Theis M, Willecke K, Itohara S. Lack of Connexin43-mediated bergmann glial gap junctional coupling does not affect cerebellar long-term depression, motor coordination, or eyeblink conditioning. Frontiers in Behavioral Neuroscience. 2: 1. PMID 18958191 DOI: 10.3389/neuro.08.001.2008  1
2008 Sakatani S, Seto-Ohshima A, Shinohara Y, Yamamoto Y, Yamamoto H, Itohara S, Hirase H. Neural-activity-dependent release of S100B from astrocytes enhances kainate-induced gamma oscillations in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10928-36. PMID 18945900 DOI: 10.1523/JNEUROSCI.3693-08.2008  1
2008 Imayoshi I, Sakamoto M, Ohtsuka T, Takao K, Miyakawa T, Yamaguchi M, Mori K, Ikeda T, Itohara S, Kageyama R. Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nature Neuroscience. 11: 1153-61. PMID 18758458 DOI: 10.1038/nn.2185  1
2008 Kojima N, Borlikova G, Sakamoto T, Yamada K, Ikeda T, Itohara S, Niki H, Endo S. Inducible cAMP early repressor acts as a negative regulator for kindling epileptogenesis and long-term fear memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6459-72. PMID 18562617 DOI: 10.1523/JNEUROSCI.0412-08.2008  1
2008 Iwasato T, Inan M, Kanki H, Erzurumlu RS, Itohara S, Crair MC. Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5931-43. PMID 18524897 DOI: 10.1523/JNEUROSCI.0815-08.2008  1
2008 Araya R, Kudo M, Kawano M, Ishii K, Hashikawa T, Iwasato T, Itohara S, Terasaki T, Oohira A, Mishina Y, Yamada M. BMP signaling through BMPRIA in astrocytes is essential for proper cerebral angiogenesis and formation of the blood-brain-barrier. Molecular and Cellular Neurosciences. 38: 417-30. PMID 18501628 DOI: 10.1016/j.mcn.2008.04.003  1
2008 Saegusa C, Kanno E, Itohara S, Fukuda M. Expression of Rab27B-binding protein Slp1 in pancreatic acinar cells and its involvement in amylase secretion. Archives of Biochemistry and Biophysics. 475: 87-92. PMID 18477466 DOI: 10.1016/  1
2008 Nasu-Nishimura Y, Taniuchi Y, Nishimura T, Sakudo A, Nakajima K, Ano Y, Sugiura K, Sakaguchi S, Itohara S, Onodera T. Cellular prion protein prevents brain damage after encephalomyocarditis virus infection in mice. Archives of Virology. 153: 1007-12. PMID 18408883 DOI: 10.1007/s00705-008-0086-x  1
2008 Obata K, Hirono M, Kume N, Kawaguchi Y, Itohara S, Yanagawa Y. GABA and synaptic inhibition of mouse cerebellum lacking glutamate decarboxylase 67. Biochemical and Biophysical Research Communications. 370: 429-33. PMID 18384748 DOI: 10.1016/j.bbrc.2008.03.110  1
2008 Li T, Ren G, Lusardi T, Wilz A, Lan JQ, Iwasato T, Itohara S, Simon RP, Boison D. Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice. The Journal of Clinical Investigation. 118: 571-82. PMID 18172552 DOI: 10.1172/JCI33737  1
2008 Zeller A, Crestani F, Camenisch I, Iwasato T, Itohara S, Fritschy JM, Rudolph U. Cortical glutamatergic neurons mediate the motor sedative action of diazepam. Molecular Pharmacology. 73: 282-91. PMID 17965197 DOI: 10.1124/mol.107.038828  1
2007 Kobayakawa K, Kobayakawa R, Matsumoto H, Oka Y, Imai T, Ikawa M, Okabe M, Ikeda T, Itohara S, Kikusui T, Mori K, Sakano H. Innate versus learned odour processing in the mouse olfactory bulb. Nature. 450: 503-8. PMID 17989651 DOI: 10.1038/nature06281  1
2007 Niimi K, Nishimura-Akiyoshi S, Nakashiba T, Itohara S. Monoclonal antibodies discriminating netrin-G1 and netrin-G2 neuronal pathways. Journal of Neuroimmunology. 192: 99-104. PMID 17945353 DOI: 10.1016/j.jneuroim.2007.09.026  1
2007 Satoh Y, Endo S, Ikeda T, Yamada K, Ito M, Kuroki M, Hiramoto T, Imamura O, Kobayashi Y, Watanabe Y, Itohara S, Takishima K. Extracellular signal-regulated kinase 2 (ERK2) knockdown mice show deficits in long-term memory; ERK2 has a specific function in learning and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10765-76. PMID 17913910 DOI: 10.1523/JNEUROSCI.0117-07.2007  1
2007 Imai Y, Inoue H, Kataoka A, Hua-Qin W, Masuda M, Ikeda T, Tsukita K, Soda M, Kodama T, Fuwa T, Honda Y, Kaneko S, Matsumoto S, Wakamatsu K, Ito S, ... ... Itohara S, et al. Pael receptor is involved in dopamine metabolism in the nigrostriatal system. Neuroscience Research. 59: 413-25. PMID 17889953 DOI: 10.1016/j.neures.2007.08.005  1
2007 Niemann S, Kanki H, Fukui Y, Takao K, Fukaya M, Hynynen MN, Churchill MJ, Shefner JM, Bronson RT, Brown RH, Watanabe M, Miyakawa T, Itohara S, Hayashi Y. Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes. The European Journal of Neuroscience. 26: 1407-20. PMID 17880385 DOI: 10.1111/j.1460-9568.2007.05774.x  1
2007 Nishimura-Akiyoshi S, Niimi K, Nakashiba T, Itohara S. Axonal netrin-Gs transneuronally determine lamina-specific subdendritic segments. Proceedings of the National Academy of Sciences of the United States of America. 104: 14801-6. PMID 17785411 DOI: 10.1073/pnas.0706919104  1
2007 Gomi H, Mori K, Itohara S, Izumi T. Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane. Molecular Biology of the Cell. 18: 4377-86. PMID 17761531 DOI: 10.1091/mbc.E07-05-0409  1
2007 Iwasato T, Katoh H, Nishimaru H, Ishikawa Y, Inoue H, Saito YM, Ando R, Iwama M, Takahashi R, Negishi M, Itohara S. Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling. Cell. 130: 742-53. PMID 17719550 DOI: 10.1016/j.cell.2007.07.022  1
2007 Tian L, Stefanidakis M, Ning L, Van Lint P, Nyman-Huttunen H, Libert C, Itohara S, Mishina M, Rauvala H, Gahmberg CG. Activation of NMDA receptors promotes dendritic spine development through MMP-mediated ICAM-5 cleavage. The Journal of Cell Biology. 178: 687-700. PMID 17682049 DOI: 10.1083/jcb.200612097  1
2007 Kim CK, Sakudo A, Taniuchi Y, Shigematsu K, Kang CB, Saeki K, Matsumoto Y, Sakaguchi S, Itohara S, Onodera T. Late-onset olfactory deficits and mitral cell loss in mice lacking prion protein with ectopic expression of Doppel. International Journal of Molecular Medicine. 20: 169-76. PMID 17611634  1
2007 Coatrieux C, Sanson M, Negre-Salvayre A, Parini A, Hannun Y, Itohara S, Salvayre R, Auge N. MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway. Free Radical Biology & Medicine. 43: 80-9. PMID 17561096 DOI: 10.1016/j.freeradbiomed.2007.03.036  1
2007 Ogiwara I, Miyamoto H, Morita N, Atapour N, Mazaki E, Inoue I, Takeuchi T, Itohara S, Yanagawa Y, Obata K, Furuichi T, Hensch TK, Yamakawa K. Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5903-14. PMID 17537961 DOI: 10.1523/JNEUROSCI.5270-06.2007  1
2007 Ohshima T, Hirasawa M, Tabata H, Mutoh T, Adachi T, Suzuki H, Saruta K, Iwasato T, Itohara S, Hashimoto M, Nakajima K, Ogawa M, Kulkarni AB, Mikoshiba K. Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development (Cambridge, England). 134: 2273-82. PMID 17507397 DOI: 10.1242/dev.02854  1
2007 Kim CK, Hirose Y, Sakudo A, Takeyama N, Kang CB, Taniuchi Y, Matsumoto Y, Itohara S, Sakaguchi S, Onodera T. Reduced response of splenocytes after mitogen-stimulation in the prion protein (PrP) gene-deficient mouse: PrPLP/Doppel production and cerebral degeneration. Biochemical and Biophysical Research Communications. 358: 469-74. PMID 17498663 DOI: 10.1016/j.bbrc.2007.04.174  1
2007 Taniwaki K, Fukamachi H, Komori K, Ohtake Y, Nonaka T, Sakamoto T, Shiomi T, Okada Y, Itoh T, Itohara S, Seiki M, Yana I. Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice. Cancer Research. 67: 4311-9. PMID 17483344 DOI: 10.1158/0008-5472.CAN-06-4761  1
2007 Mizoguchi H, Yamada K, Mouri A, Niwa M, Mizuno T, Noda Y, Nitta A, Itohara S, Banno Y, Nabeshima T. Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine-induced behavioral sensitization and reward: implications for dopamine receptor down-regulation and dopamine release. Journal of Neurochemistry. 102: 1548-60. PMID 17472698 DOI: 10.1111/j.1471-4159.2007.04623.x  1
2007 Nakade K, Pan J, Yoshiki A, Ugai H, Kimura M, Liu B, Li H, Obata Y, Iwama M, Itohara S, Murata T, Yokoyama KK. JDP2 suppresses adipocyte differentiation by regulating histone acetylation. Cell Death and Differentiation. 14: 1398-405. PMID 17464331 DOI: 10.1038/sj.cdd.4402129  1
2007 Nishimura T, Sakudo A, Hashiyama Y, Yachi A, Saeki K, Matsumoto Y, Ogawa M, Sakaguchi S, Itohara S, Onodera T. Serum withdrawal-induced apoptosis in ZrchI prion protein (PrP) gene-deficient neuronal cell line is suppressed by PrP, independent of Doppel. Microbiology and Immunology. 51: 457-66. PMID 17446686 DOI: JST.JSTAGE/mandi/51.457  1
2007 Earnheart JC, Schweizer C, Crestani F, Iwasato T, Itohara S, Mohler H, Lüscher B. GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3845-54. PMID 17409249 DOI: 10.1523/JNEUROSCI.3609-06.2007  1
2007 Aiba A, Inokuchi K, Ishida Y, Itohara S, Kobayashi K, Masu M, Mishina M, Miyakawa T, Mori H, Nakao K, Obata Y, Sakimura K, Shiroishi T, Wada K, Yagi T. Mouse liaison for integrative brain research. Neuroscience Research. 58: 103-4. PMID 17382419 DOI: 10.1016/j.neures.2007.02.012  1
2007 Sadakata T, Washida M, Iwayama Y, Shoji S, Sato Y, Ohkura T, Katoh-Semba R, Nakajima M, Sekine Y, Tanaka M, Nakamura K, Iwata Y, Tsuchiya KJ, Mori N, Detera-Wadleigh SD, ... ... Itohara S, et al. Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients. The Journal of Clinical Investigation. 117: 931-43. PMID 17380209 DOI: 10.1172/JCI29031  1
2007 Mizoguchi H, Yamada K, Niwa M, Mouri A, Mizuno T, Noda Y, Nitta A, Itohara S, Banno Y, Nabeshima T. Reduction of methamphetamine-induced sensitization and reward in matrix metalloproteinase-2 and -9-deficient mice. Journal of Neurochemistry. 100: 1579-88. PMID 17348864 DOI: 10.1111/j.1471-4159.2006.04288.x  1
2007 Sadakata T, Kakegawa W, Mizoguchi A, Washida M, Katoh-Semba R, Shutoh F, Okamoto T, Nakashima H, Kimura K, Tanaka M, Sekine Y, Itohara S, Yuzaki M, Nagao S, Furuichi T. Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2472-82. PMID 17344385 DOI: 10.1523/JNEUROSCI.2279-06.2007  1
2007 Sakatani S, Seto-Ohshima A, Itohara S, Hirase H. Impact of S100B on local field potential patterns in anesthetized and kainic acid-induced seizure conditions in vivo. The European Journal of Neuroscience. 25: 1144-54. PMID 17331210 DOI: 10.1111/j.1460-9568.2007.05337.x  1
2007 Tanaka KF, Takebayashi H, Yamazaki Y, Ono K, Naruse M, Iwasato T, Itohara S, Kato H, Ikenaka K. Murine model of Alexander disease: analysis of GFAP aggregate formation and its pathological significance. Glia. 55: 617-31. PMID 17299771 DOI: 10.1002/glia.20486  1
2007 Naito Y, Takematsu H, Koyama S, Miyake S, Yamamoto H, Fujinawa R, Sugai M, Okuno Y, Tsujimoto G, Yamaji T, Hashimoto Y, Itohara S, Kawasaki T, Suzuki A, Kozutsumi Y. Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation. Molecular and Cellular Biology. 27: 3008-22. PMID 17296732 DOI: 10.1128/MCB.02047-06  1
2007 Tellier E, Nègre-Salvayre A, Bocquet B, Itohara S, Hannun YA, Salvayre R, Augé N. Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway. Molecular and Cellular Biology. 27: 2997-3007. PMID 17283058 DOI: 10.1128/MCB.01485-06  1
2007 Kitao Y, Imai Y, Ozawa K, Kataoka A, Ikeda T, Soda M, Nakimawa K, Kiyama H, Stern DM, Hori O, Wakamatsu K, Ito S, Itohara S, Takahashi R, Ogawa S. Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Human Molecular Genetics. 16: 50-60. PMID 17116640 DOI: 10.1093/hmg/ddl439  1
2007 Yokoyama T, Shimada K, Masujin K, Iwamaru Y, Imamura M, Ushiki YK, Kimura KM, Itohara S, Shinagawa M. Both host prion protein 131-188 subregion and prion strain characteristics regulate glycoform of PrP Sc. Archives of Virology. 152: 603-9. PMID 17106625 DOI: 10.1007/s00705-006-0858-0  1
2007 He JZ, Quan A, Xu Y, Teoh H, Wang G, Fish JE, Steer BM, Itohara S, Marsden PA, Davidge ST, Ward ME. Induction of matrix metalloproteinase-2 enhances systemic arterial contraction after hypoxia. American Journal of Physiology. Heart and Circulatory Physiology. 292: H684-93. PMID 16980344 DOI: 10.1152/ajpheart.00538.2006  1
2006 Sano Y, Nakaya T, Pedrini S, Takeda S, Iijima-Ando K, Iijima K, Mathews PM, Itohara S, Gandy S, Suzuki T. Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP. Plos One. 1: e51. PMID 17183681 DOI: 10.1371/journal.pone.0000051  1
2006 Sano Y, Syuzo-Takabatake A, Nakaya T, Saito Y, Tomita S, Itohara S, Suzuki T. Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain. The Journal of Biological Chemistry. 281: 37853-60. PMID 17032642 DOI: 10.1074/jbc.M609312200  1
2006 Nakaji K, Ihara M, Takahashi C, Itohara S, Noda M, Takahashi R, Tomimoto H. Matrix metalloproteinase-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in rodents. Stroke; a Journal of Cerebral Circulation. 37: 2816-23. PMID 17008622 DOI: 10.1161/01.STR.0000244808.17972.55  1
2006 Inoue K, Mikuni-Takagaki Y, Oikawa K, Itoh T, Inada M, Noguchi T, Park JS, Onodera T, Krane SM, Noda M, Itohara S. A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism. The Journal of Biological Chemistry. 281: 33814-24. PMID 16959767 DOI: 10.1074/jbc.M607290200  1
2006 Araya R, Noguchi T, Yuhki M, Kitamura N, Higuchi M, Saido TC, Seki K, Itohara S, Kawano M, Tanemura K, Takashima A, Yamada K, Kondoh Y, Kanno I, Wess J, et al. Loss of M5 muscarinic acetylcholine receptors leads to cerebrovascular and neuronal abnormalities and cognitive deficits in mice. Neurobiology of Disease. 24: 334-44. PMID 16956767 DOI: 10.1016/j.nbd.2006.07.010  1
2006 Cappello S, Attardo A, Wu X, Iwasato T, Itohara S, Wilsch-Bräuninger M, Eilken HM, Rieger MA, Schroeder TT, Huttner WB, Brakebusch C, Götz M. The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nature Neuroscience. 9: 1099-107. PMID 16892058 DOI: 10.1038/nn1744  1
2006 Saegusa C, Tanaka T, Tani S, Itohara S, Mikoshiba K, Fukuda M. Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 623-31. PMID 16716193 DOI: 10.1111/j.1365-2443.2006.00964.x  1
2006 Kanki H, Suzuki H, Itohara S. High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Experimental Animals / Japanese Association For Laboratory Animal Science. 55: 137-41. PMID 16651697 DOI: JST.JSTAGE/expanim/55.137  1
2006 Park JS, Onodera T, Nishimura S, Thompson RF, Itohara S. Molecular evidence for two-stage learning and partial laterality in eyeblink conditioning of mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 5549-54. PMID 16569693 DOI: 10.1073/pnas.0601150103  1
2006 Kuzuya M, Nakamura K, Sasaki T, Cheng XW, Itohara S, Iguchi A. Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1120-5. PMID 16556856 DOI: 10.1161/01.ATV.0000218496.60097.e0  1
2006 Lee DC, Sakudo A, Kim CK, Nishimura T, Saeki K, Matsumoto Y, Yokoyama T, Chen SG, Itohara S, Onodera T. Fusion of Doppel to octapeptide repeat and N-terminal half of hydrophobic region of prion protein confers resistance to serum deprivation. Microbiology and Immunology. 50: 203-9. PMID 16547418 DOI: JST.JSTAGE/mandi/50.203  1
2006 Shutoh F, Ohki M, Kitazawa H, Itohara S, Nagao S. Memory trace of motor learning shifts transsynaptically from cerebellar cortex to nuclei for consolidation. Neuroscience. 139: 767-77. PMID 16458438 DOI: 10.1016/j.neuroscience.2005.12.035  1
2005 Gomi H, Mizutani S, Kasai K, Itohara S, Izumi T. Granuphilin molecularly docks insulin granules to the fusion machinery. The Journal of Cell Biology. 171: 99-109. PMID 16216924 DOI: 10.1083/jcb.200505179  1
2005 Miyashita T, Nishimura-Akiyoshi S, Itohara S, Rockland KS. Strong expression of NETRIN-G2 in the monkey claustrum. Neuroscience. 136: 487-96. PMID 16203099 DOI: 10.1016/j.neuroscience.2005.08.025  1
2005 Sakudo A, Lee DC, Nakamura I, Taniuchi Y, Saeki K, Matsumoto Y, Itohara S, Ikuta K, Onodera T. Cell-autonomous PrP-Doppel interaction regulates apoptosis in PrP gene-deficient neuronal cells. Biochemical and Biophysical Research Communications. 333: 448-54. PMID 15950943 DOI: 10.1016/j.bbrc.2005.05.128  1
2005 Meerabux JM, Ohba H, Fukasawa M, Suto Y, Aoki-Suzuki M, Nakashiba T, Nishimura S, Itohara S, Yoshikawa T. Human netrin-G1 isoforms show evidence of differential expression. Genomics. 86: 112-6. PMID 15901489 DOI: 10.1016/j.ygeno.2005.04.004  1
2005 Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron. 46: 433-44. PMID 15882643 DOI: 10.1016/j.neuron.2005.03.025  1
2005 Lee LJ, Iwasato T, Itohara S, Erzurumlu RS. Exuberant thalamocortical axon arborization in cortex-specific NMDAR1 knockout mice. The Journal of Comparative Neurology. 485: 280-92. PMID 15803506 DOI: 10.1002/cne.20481  1
2005 Fernández FG, Campbell LG, Liu W, Shipley JM, Itohara S, Patterson GA, Senior RM, Mohanakumar T, Jaramillo A. Inhibition of obliterative airway disease development in murine tracheal allografts by matrix metalloproteinase-9 deficiency. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 671-83. PMID 15760390 DOI: 10.1111/j.1600-6143.2005.00751.x  1
2005 Ihara M, Kinoshita A, Yamada S, Tanaka H, Tanigaki A, Kitano A, Goto M, Okubo K, Nishiyama H, Ogawa O, Takahashi C, Itohara S, Nishimune Y, Noda M, Kinoshita M. Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa. Developmental Cell. 8: 343-52. PMID 15737930 DOI: 10.1016/j.devcel.2004.12.005  0.96
2005 Campbell LG, Ramachandran S, Liu W, Shipley JM, Itohara S, Rogers JG, Moazami N, Senior RM, Jaramillo A. Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 517-28. PMID 15707406 DOI: 10.1111/j.1600-6143.2005.00744.x  1
2005 Aoki-Suzuki M, Yamada K, Meerabux J, Iwayama-Shigeno Y, Ohba H, Iwamoto K, Takao H, Toyota T, Suto Y, Nakatani N, Dean B, Nishimura S, Seki K, Kato T, Itohara S, et al. A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia. Biological Psychiatry. 57: 382-93. PMID 15705354 DOI: 10.1016/j.biopsych.2004.11.022  1
2005 Higuchi M, Tomioka M, Takano J, Shirotani K, Iwata N, Masumoto H, Maki M, Itohara S, Saido TC. Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors. The Journal of Biological Chemistry. 280: 15229-37. PMID 15699033 DOI: 10.1074/jbc.M500939200  1
2005 Takano J, Tomioka M, Tsubuki S, Higuchi M, Iwata N, Itohara S, Maki M, Saido TC. Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: evidence from calpastatin mutant mice. The Journal of Biological Chemistry. 280: 16175-84. PMID 15691848 DOI: 10.1074/jbc.M414552200  1
2005 Sakudo A, Lee DC, Li S, Nakamura T, Matsumoto Y, Saeki K, Itohara S, Ikuta K, Onodera T. PrP cooperates with STI1 to regulate SOD activity in PrP-deficient neuronal cell line. Biochemical and Biophysical Research Communications. 328: 14-9. PMID 15670743 DOI: 10.1016/j.bbrc.2004.12.132  1
2005 Sakudo A, Lee DC, Nishimura T, Li S, Tsuji S, Nakamura T, Matsumoto Y, Saeki K, Itohara S, Ikuta K, Onodera T. Octapeptide repeat region and N-terminal half of hydrophobic region of prion protein (PrP) mediate PrP-dependent activation of superoxide dismutase. Biochemical and Biophysical Research Communications. 326: 600-6. PMID 15596141 DOI: 10.1016/j.bbrc.2004.11.092  1
2004 Michishita M, Ikeda T, Nakashiba T, Ogawa M, Tashiro K, Honjo T, Doi K, Itohara S, Endo S. Expression of Btcl2, a novel member of Btcl gene family, during development of the central nervous system. Brain Research. Developmental Brain Research. 153: 135-42. PMID 15464227 DOI: 10.1016/j.devbrainres.2004.06.012  1
2004 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y. Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. The Journal of Comparative Neurology. 479: 243-56. PMID 15457507 DOI: 10.1002/cne.20270  1
2004 Nishimura T, Sakudo A, Nakamura I, Lee DC, Taniuchi Y, Saeki K, Matsumoto Y, Ogawa M, Sakaguchi S, Itohara S, Onodera T. Cellular prion protein regulates intracellular hydrogen peroxide level and prevents copper-induced apoptosis. Biochemical and Biophysical Research Communications. 323: 218-22. PMID 15351724 DOI: 10.1016/j.bbrc.2004.08.087  1
2004 Ichihara G, Li W, Shibata E, Ding X, Wang H, Liang Y, Peng S, Itohara S, Kamijima M, Fan Q, Zhang Y, Zhong E, Wu X, Valentine WM, Takeuchi Y. Neurologic abnormalities in workers of a 1-bromopropane factory. Environmental Health Perspectives. 112: 1319-25. PMID 15345346 DOI: 10.1289/ehp.6995  0.32
2004 Tateno M, Sadakata H, Tanaka M, Itohara S, Shin RM, Miura M, Masuda M, Aosaki T, Urushitani M, Misawa H, Takahashi R. Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model. Human Molecular Genetics. 13: 2183-96. PMID 15294873 DOI: 10.1093/hmg/ddh246  1
2004 Augé N, Maupas-Schwalm F, Elbaz M, Thiers JC, Waysbort A, Itohara S, Krell HW, Salvayre R, Nègre-Salvayre A. Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation. Circulation. 110: 571-8. PMID 15277330 DOI: 10.1161/01.CIR.0000136995.83451.1D  1
2004 Inoue T, Hatayama M, Tohmonda T, Itohara S, Aruga J, Mikoshiba K. Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives. Developmental Biology. 270: 146-62. PMID 15136147 DOI: 10.1016/j.ydbio.2004.02.017  1
2004 Kamijima M, Hibi H, Gotoh M, Taki K, Saito I, Wang H, Itohara S, Yamada T, Ichihara G, Shibata E, Nakajima T, Takeuchi Y. A survey of semen indices in insecticide sprayers. Journal of Occupational Health. 46: 109-18. PMID 15090685 DOI: 10.1539/joh.46.109  0.32
2004 Yuhki M, Yamada M, Kawano M, Iwasato T, Itohara S, Yoshida H, Ogawa M, Mishina Y. BMPR1A signaling is necessary for hair follicle cycling and hair shaft differentiation in mice. Development (Cambridge, England). 131: 1825-33. PMID 15084466 DOI: 10.1242/dev.01079  1
2004 Oh J, Takahashi R, Adachi E, Kondo S, Kuratomi S, Noma A, Alexander DB, Motoda H, Okada A, Seiki M, Itoh T, Itohara S, Takahashi C, Noda M. Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice. Oncogene. 23: 5041-8. PMID 15064723 DOI: 10.1038/sj.onc.1207688  1
2004 Iwasato T, Nomura R, Ando R, Ikeda T, Tanaka M, Itohara S. Dorsal telencephalon-specific expression of Cre recombinase in PAC transgenic mice. Genesis (New York, N.Y. : 2000). 38: 130-8. PMID 15048810 DOI: 10.1002/gene.20009  1
2004 Sakudo A, Lee DC, Yoshimura E, Nagasaka S, Nitta K, Saeki K, Matsumoto Y, Lehmann S, Itohara S, Sakaguchi S, Onodera T. Prion protein suppresses perturbation of cellular copper homeostasis under oxidative conditions. Biochemical and Biophysical Research Communications. 313: 850-5. PMID 14706620 DOI: 10.1016/j.bbrc.2003.12.020  1
2004 Ichihara G, Li W, Ding X, Peng S, Yu X, Shibata E, Yamada T, Wang H, Itohara S, Kanno S, Sakai K, Ito H, Kanefusa K, Takeuchi Y. A survey on exposure level, health status, and biomarkers in workers exposed to 1-bromopropane. American Journal of Industrial Medicine. 45: 63-75. PMID 14691970 DOI: 10.1002/ajim.10320  0.32
2004 Yoshida K, Furuya S, Osuka S, Mitoma J, Shinoda Y, Watanabe M, Azuma N, Tanaka H, Hashikawa T, Itohara S, Hirabayashi Y. Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality. The Journal of Biological Chemistry. 279: 3573-7. PMID 14645240 DOI: 10.1074/jbc.C300507200  1
2004 Sassa T, Gomi H, Itohara S. Postnatal expression of Cdkl2 in mouse brain revealed by LacZ inserted into the Cdkl2 locus. Cell and Tissue Research. 315: 147-56. PMID 14605869 DOI: 10.1007/s00441-003-0828-8  1
2003 Hoshino S, Inoue K, Yokoyama T, Kobayashi S, Asakura T, Teramoto A, Itohara S. Prions prevent brain damage after experimental brain injury: a preliminary report. Acta Neurochirurgica. Supplement. 86: 297-9. PMID 14753456  1
2003 Seto-Ohshima A, Kitajima S, Ito M, Inoue M, Murashima YL, Yamakawa K, Itohara S. Stimulus-induced behavior in F1 hybrids of seizure-sensitive and seizure-resistant gerbils. Zoological Science. 20: 1439-45. PMID 14709808 DOI: 10.2108/zsj.20.1439  1
2003 Inoue H, Tsukita K, Iwasato T, Suzuki Y, Tomioka M, Tateno M, Nagao M, Kawata A, Saido TC, Miura M, Misawa H, Itohara S, Takahashi R. The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model. The Embo Journal. 22: 6665-74. PMID 14657037 DOI: 10.1093/emboj/cdg634  1
2003 Nakamura Y, Sakudo A, Saeki K, Kaneko T, Matsumoto Y, Toniolo A, Itohara S, Onodera T. Transfection of prion protein gene suppresses coxsackievirus B3 replication in prion protein gene-deficient cells. The Journal of General Virology. 84: 3495-502. PMID 14645931 DOI: 10.1099/vir.0.19222-0  1
2003 Sakudo A, Lee DC, Saeki K, Matsumoto Y, Itohara S, Onodera T. Tumor necrosis factor attenuates prion protein-deficient neuronal cell death by increases in anti-apoptotic Bcl-2 family proteins. Biochemical and Biophysical Research Communications. 310: 725-9. PMID 14550262 DOI: 10.1016/j.bbrc.2003.09.068  1
2003 Wiseman BS, Sternlicht MD, Lund LR, Alexander CM, Mott J, Bissell MJ, Soloway P, Itohara S, Werb Z. Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis. The Journal of Cell Biology. 162: 1123-33. PMID 12975354 DOI: 10.1083/jcb.200302090  1
2003 Kuzuya M, Kanda S, Sasaki T, Tamaya-Mori N, Cheng XW, Itoh T, Itohara S, Iguchi A. Deficiency of gelatinase a suppresses smooth muscle cell invasion and development of experimental intimal hyperplasia. Circulation. 108: 1375-81. PMID 12939223 DOI: 10.1161/01.CIR.0000086463.15540.3C  1
2003 Sakudo A, Lee DC, Saeki K, Nakamura Y, Inoue K, Matsumoto Y, Itohara S, Onodera T. Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line. Biochemical and Biophysical Research Communications. 308: 660-7. PMID 12914801 DOI: 10.1016/S0006-291X(03)01459-1  1
2003 Ishida D, Kometani K, Yang H, Kakugawa K, Masuda K, Iwai K, Suzuki M, Itohara S, Nakahata T, Hiai H, Kawamoto H, Hattori M, Minato N. Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice. Cancer Cell. 4: 55-65. PMID 12892713 DOI: 10.1016/S1535-6108(03)00163-6  1
2003 Kubosaki A, Nishimura-Nasu Y, Nishimura T, Yusa S, Sakudo A, Saeki K, Matsumoto Y, Itohara S, Onodera T. Expression of normal cellular prion protein (PrP(c)) on T lymphocytes and the effect of copper ion: Analysis by wild-type and prion protein gene-deficient mice. Biochemical and Biophysical Research Communications. 307: 810-3. PMID 12878182 DOI: 10.1016/S0006-291X(03)01263-4  1
2003 Shutoh F, Katoh A, Ohki M, Itohara S, Tonegawa S, Nagao S. Role of protein kinase C family in the cerebellum-dependent adaptive learning of horizontal optokinetic response eye movements in mice. The European Journal of Neuroscience. 18: 134-42. PMID 12859346 DOI: 10.1046/j.1460-9568.2003.02717.x  1
2003 Michishita M, Ikeda T, Nakashiba T, Ogawa M, Tashiro K, Honjo T, Doi K, Itohara S, Endo S. A novel gene, Btcl1, encoding CUB and LDLa domains is expressed in restricted areas of mouse brain. Biochemical and Biophysical Research Communications. 306: 680-6. PMID 12810072 DOI: 10.1016/S0006-291X(03)01035-0  1
2003 Inoue K, Ozaki S, Ito K, Iseda T, Kawaguchi S, Ogawa M, Bae SC, Yamashita N, Itohara S, Kudo N, Ito Y. Runx3 is essential for the target-specific axon pathfinding of trkc-expressing dorsal root ganglion neurons. Blood Cells, Molecules & Diseases. 30: 157-60. PMID 12732177 DOI: 10.1016/S1079-9796(03)00032-9  1
2003 Nakahara J, Takemura M, Gomi H, Tsunematsu K, Itohara S, Asou H, Ogawa M, Aiso S, Tan-Takeuchi K. Role of radial fibers in controlling the onset of myelination. Journal of Neuroscience Research. 72: 279-89. PMID 12692895 DOI: 10.1002/jnr.10593  1
2003 Berglin L, Sarman S, van der Ploeg I, Steen B, Ming Y, Itohara S, Seregard S, Kvanta A. Reduced choroidal neovascular membrane formation in matrix metalloproteinase-2-deficient mice. Investigative Ophthalmology & Visual Science. 44: 403-8. PMID 12506102 DOI: 10.1167/iovs.02-0180  1
2002 Nakajima T, Ichihara G, Kamijima M, Itohara S, Aoyama T. Functional activation of peroxisome proliferator-activated receptor alpha (PPARalpha) by environmental chemicals in relation to their toxicities. Nagoya Journal of Medical Science. 65: 85-94. PMID 12580534  0.32
2002 Datwani A, Iwasato T, Itohara S, Erzurumlu RS. NMDA receptor-dependent pattern transfer from afferents to postsynaptic cells and dendritic differentiation in the barrel cortex. Molecular and Cellular Neurosciences. 21: 477-92. PMID 12498788 DOI: 10.1006/mcne.2002.1195  1
2002 Datwani A, Iwasato T, Itohara S, Erzurumlu RS. Lesion-induced thalamocortical axonal plasticity in the S1 cortex is independent of NMDA receptor function in excitatory cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9171-5. PMID 12417641  1
2002 Inoue K, Ozaki S, Shiga T, Ito K, Masuda T, Okado N, Iseda T, Kawaguchi S, Ogawa M, Bae SC, Yamashita N, Itohara S, Kudo N, Ito Y. Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons. Nature Neuroscience. 5: 946-54. PMID 12352981 DOI: 10.1038/nn925  1
2002 Takahashi M, Fukami S, Iwata N, Inoue K, Itohara S, Itoh H, Haraoka J, Saido T. In vivo glioma growth requires host-derived matrix metalloproteinase 2 for maintenance of angioarchitecture. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 46: 155-63. PMID 12220955 DOI: 10.1016/S1043-6618(02)00081-6  1
2002 Itoh T, Matsuda H, Tanioka M, Kuwabara K, Itohara S, Suzuki R. The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis. Journal of Immunology (Baltimore, Md. : 1950). 169: 2643-7. PMID 12193736  1
2002 Takemura M, Gomi H, Colucci-Guyon E, Itohara S. Protective role of phosphorylation in turnover of glial fibrillary acidic protein in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6972-9. PMID 12177195  1
2002 Kitamoto T, Mohri S, Ironside JW, Miyoshi I, Tanaka T, Kitamoto N, Itohara S, Kasai N, Katsuki M, Higuchi J, Muramoto T, Shin RW. Follicular dendritic cell of the knock-in mouse provides a new bioassay for human prions. Biochemical and Biophysical Research Communications. 294: 280-6. PMID 12051707 DOI: 10.1016/S0006-291X(02)00476-X  1
2002 Ganesh S, Delgado-Escueta AV, Sakamoto T, Avila MR, Machado-Salas J, Hoshii Y, Akagi T, Gomi H, Suzuki T, Amano K, Agarwala KL, Hasegawa Y, Bai DS, Ishihara T, Hashikawa T, ... Itohara S, et al. Targeted disruption of the Epm2a gene causes formation of Lafora inclusion bodies, neurodegeneration, ataxia, myoclonus epilepsy and impaired behavioral response in mice. Human Molecular Genetics. 11: 1251-62. PMID 12019206  1
2002 Wang H, Ichihara G, Ito H, Kato K, Kitoh J, Yamada T, Yu X, Tsuboi S, Moriyama Y, Sakatani R, Shibata E, Kamijima M, Itohara S, Takeuchi Y. Biochemical changes in the central nervous system of rats exposed to 1-bromopropane for seven days. Toxicological Sciences : An Official Journal of the Society of Toxicology. 67: 114-20. PMID 11961224 DOI: 10.1093/toxsci/67.1.114  0.32
2002 Li QL, Ito K, Sakakura C, Fukamachi H, Inoue Ki, Chi XZ, Lee KY, Nomura S, Lee CW, Han SB, Kim HM, Kim WJ, Yamamoto H, Yamashita N, Yano T, ... ... Itohara S, et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell. 109: 113-24. PMID 11955451 DOI: 10.1016/S0092-8674(02)00690-6  1
2002 Takemura M, Nishiyama H, Itohara S. Distribution of phosphorylated glial fibrillary acidic protein in the mouse central nervous system. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 7: 295-307. PMID 11918673 DOI: 10.1046/j.1365-2443.2002.00513.x  1
2002 Nishiyama H, Knopfel T, Endo S, Itohara S. Glial protein S100B modulates long-term neuronal synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 99: 4037-42. PMID 11891290 DOI: 10.1073/pnas.052020999  1
2002 Nishiyama H, Takemura M, Takeda T, Itohara S. Normal development of serotonergic neurons in mice lacking S100B. Neuroscience Letters. 321: 49-52. PMID 11872254 DOI: 10.1016/S0304-3940(01)02549-6  1
2002 Metzger F, Repunte-Canonigo V, Matsushita S, Akemann W, Diez-Garcia J, Ho CS, Iwasato T, Grandes P, Itohara S, Joho RH, Knöpfel T. Transgenic mice expressing a pH and Cl- sensing yellow-fluorescent protein under the control of a potassium channel promoter. The European Journal of Neuroscience. 15: 40-50. PMID 11860505 DOI: 10.1046/j.0953-816x.2001.01837.x  1
2002 Sugaya M, Nakamura K, Watanabe T, Asahina A, Yasaka N, Koyama Yi, Kusubata M, Ushiki Y, Kimura K, Morooka A, Irie S, Yokoyama T, Inoue K, Itohara S, Tamaki K. Expression of cellular prion-related protein by murine Langerhans cells and keratinocytes. Journal of Dermatological Science. 28: 126-34. PMID 11858951 DOI: 10.1016/S0923-1811(01)00160-8  1
2002 Shutoh F, Katoh A, Kitazawa H, Aiba A, Itohara S, Nagao S. Loss of adaptability of horizontal optokinetic response eye movements in mGluR1 knockout mice. Neuroscience Research. 42: 141-5. PMID 11849733 DOI: 10.1016/S0168-0102(01)00308-X  1
2002 Nakashiba T, Nishimura S, Ikeda T, Itohara S. Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Mechanisms of Development. 111: 47-60. PMID 11804778 DOI: 10.1016/S0925-4773(01)00600-1  1
2002 Tanaka H, Katoh A, Oguro K, Shimazaki K, Gomi H, Itohara S, Masuzawa T, Kawai N. Disturbance of hippocampal long-term potentiation after transient ischemia in GFAP deficient mice. Journal of Neuroscience Research. 67: 11-20. PMID 11754076 DOI: 10.1002/jnr.10004  0.36
2002 Kamijima M, Sakai K, Shibata E, Yamada T, Itohara S, Ohno H, Hayakawa R, Sugiura M, Yamaki K, Takeuchi Y. 2-Ethyl-1-hexanol in indoor air as a possible cause of sick building symptoms Journal of Occupational Health. 44: 186-191. DOI: 10.1539/joh.44.186  0.32
2002 Ichihara G, Miller JK, Ziolkowska A, Itohara S, Takeuchi Y. Neurological disorders in three workers exposed to 1-bromopropane Journal of Occupational Health. 44: 1-7. DOI: 10.1539/joh.44.1  0.32
2001 Oh J, Takahashi R, Kondo S, Mizoguchi A, Adachi E, Sasahara RM, Nishimura S, Imamura Y, Kitayama H, Alexander DB, Ide C, Horan TP, Arakawa T, Yoshida H, Nishikawa S, ... ... Itohara S, et al. The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell. 107: 789-800. PMID 11747814 DOI: 10.1016/S0092-8674(01)00597-9  1
2001 Kato T, Kure T, Chang JH, Gabison EE, Itoh T, Itohara S, Azar DT. Diminished corneal angiogenesis in gelatinase A-deficient mice. Febs Letters. 508: 187-90. PMID 11718713 DOI: 10.1016/S0014-5793(01)02897-6  1
2001 Wielockx B, Lannoy K, Shapiro SD, Itoh T, Itohara S, Vandekerckhove J, Libert C. Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy. Nature Medicine. 7: 1202-8. PMID 11689884 DOI: 10.1038/nm1101-1202  1
2001 Asahi M, Sumii T, Fini ME, Itohara S, Lo EH. Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia. Neuroreport. 12: 3003-7. PMID 11588620  1
2001 Kubosaki A, Yusa S, Nasu Y, Nishimura T, Nakamura Y, Saeki K, Matsumoto Y, Itohara S, Onodera T. Distribution of cellular isoform of prion protein in T lymphocytes and bone marrow, analyzed by wild-type and prion protein gene-deficient mice. Biochemical and Biophysical Research Communications. 282: 103-7. PMID 11263978 DOI: 10.1006/bbrc.2001.4538  1
2001 Yokoyama T, Kimura KM, Ushiki Y, Yamada S, Morooka A, Nakashiba T, Sassa T, Itohara S. In vivo conversion of cellular prion protein to pathogenic isoforms, as monitored by conformation-specific antibodies. The Journal of Biological Chemistry. 276: 11265-71. PMID 11152682 DOI: 10.1074/jbc.M008734200  1
2000 Tanaka S, Itohara S, Sato M, Taniguchi T, Yokomizo Y. Reduced formation of granulomata in gamma(delta) T cell knockout BALB/c mice inoculated with Mycobacterium avium subsp. paratuberculosis. Veterinary Pathology. 37: 415-21. PMID 11055864  1
2000 Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nature Cell Biology. 2: 737-44. PMID 11025665 DOI: 10.1038/35036374  1
2000 Nagai N, Hosokawa M, Itohara S, Adachi E, Matsushita T, Hosokawa N, Nagata K. Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. The Journal of Cell Biology. 150: 1499-506. PMID 10995453 DOI: 10.1083/jcb.150.6.1499  1
2000 Nakashiba T, Ikeda T, Nishimura S, Tashiro K, Honjo T, Culotti JG, Itohara S. Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6540-50. PMID 10964959  1
2000 Iwasato T, Datwani A, Wolf AM, Nishiyama H, Taguchi Y, Tonegawa S, Knöpfel T, Erzurumlu RS, Itohara S. Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex. Nature. 406: 726-31. PMID 10963597 DOI: 10.1038/35021059  1
2000 Katoh A, Kitazawa H, Itohara S, Nagao S. Inhibition of nitric oxide synthesis and gene knockout of neuronal nitric oxide synthase impaired adaptation of mouse optokinetic response eye movements. Learning & Memory (Cold Spring Harbor, N.Y.). 7: 220-6. PMID 10940322 DOI: 10.1101/lm.7.4.220  1
2000 Iijima K, Ando K, Takeda S, Satoh Y, Seki T, Itohara S, Greengard P, Kirino Y, Nairn AC, Suzuki T. Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5. Journal of Neurochemistry. 75: 1085-91. PMID 10936190 DOI: 10.1046/j.1471-4159.2000.0751085.x  1
2000 Naiki Y, Nishimura H, Itohara S, Yoshikai Y. gammadelta T cells may dichotomously modulate infection with avirulent Salmonella choleraesuis via IFN-gamma and IL-13 in mice. Cellular Immunology. 202: 61-9. PMID 10873307 DOI: 10.1006/cimm.2000.1659  1
2000 Sassa T, Gomi H, Sun W, Ikeda T, Thompson RF, Itohara S. Identification of variants and dual promoters of murine serine/threonine kinase KKIAMRE. Journal of Neurochemistry. 74: 1809-19. PMID 10800923 DOI: 10.1046/j.1471-4159.2000.0741809.x  1
2000 Moriya T, Yoshinobu Y, Kouzu Y, Katoh A, Gomi H, Ikeda M, Yoshioka T, Itohara S, Shibata S. Involvement of glial fibrillary acidic protein (GFAP) expressed in astroglial cells in circadian rhythm under constant lighting conditions in mice. Journal of Neuroscience Research. 60: 212-8. PMID 10740226 DOI: 10.1002/(SICI)1097-4547(20000415)60:2<212::AID-JNR10>3.0.CO;2-P  1
1999 Futatsugi A, Kato K, Ogura H, Li ST, Nagata E, Kuwajima G, Tanaka K, Itohara S, Mikoshiba K. Facilitation of NMDAR-independent LTP and spatial learning in mutant mice lacking ryanodine receptor type 3. Neuron. 24: 701-13. PMID 10595520 DOI: 10.1016/S0896-6273(00)81123-X  1
1999 Sakaguchi G, Manabe T, Kobayashi K, Orita S, Sasaki T, Naito A, Maeda M, Igarashi H, Katsuura G, Nishioka H, Mizoguchi A, Itohara S, Takahashi T, Takai Y. Doc2alpha is an activity-dependent modulator of excitatory synaptic transmission. The European Journal of Neuroscience. 11: 4262-8. PMID 10594652 DOI: 10.1046/j.1460-9568.1999.00855.x  1
1999 Minoguchi S, Ikeda T, Itohara S, Kaneko T, Okaichi H, Honjo T. Studies on the cell-type specific expression of RBP-L, a RBP-J family member, by replacement insertion of beta-galactosidase. Journal of Biochemistry. 126: 738-47. PMID 10502683  1
1999 Hoq MM, Suzutani T, Nakaya K, Yoshida I, Ogasawara M, Takeda Y, Shibaki T, Itohara S, Yamamoto H, Azuma M. Insufficient resistance of trehalose-6,6-dimycolate-treated T-cell receptor delta gene mutant (TCR delta-/-) mice against influenza virus infection. Microbiology and Immunology. 43: 491-3. PMID 10449256  1
1999 Naiki Y, Nishimura H, Kawano T, Tanaka Y, Itohara S, Taniguchi M, Yoshikai Y. Regulatory role of peritoneal NK1.1+ alpha beta T cells in IL-12 production during Salmonella infection. Journal of Immunology (Baltimore, Md. : 1950). 163: 2057-63. PMID 10438944  1
1999 Kuwahara C, Takeuchi AM, Nishimura T, Haraguchi K, Kubosaki A, Matsumoto Y, Saeki K, Matsumoto Y, Yokoyama T, Itohara S, Onodera T. Prions prevent neuronal cell-line death. Nature. 400: 225-6. PMID 10421360 DOI: 10.1038/22241  1
1998 Katoh A, Kitazawa H, Itohara S, Nagao S. Dynamic characteristics and adaptability of mouse vestibulo-ocular and optokinetic response eye movements and the role of the flocculo-olivary system revealed by chemical lesions. Proceedings of the National Academy of Sciences of the United States of America. 95: 7705-10. PMID 9636214 DOI: 10.1073/pnas.95.13.7705  1
1998 Takano M, Nishimura H, Kimura Y, Mokuno Y, Washizu J, Itohara S, Nimura Y, Yoshikai Y. Protective roles of gamma delta T cells and interleukin-15 in Escherichia coli infection in mice. Infection and Immunity. 66: 3270-8. PMID 9632595  1
1998 Itoh T, Tanioka M, Yoshida H, Yoshioka T, Nishimoto H, Itohara S. Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Research. 58: 1048-51. PMID 9500469  1
1997 Silva AJ, Simpson EM, Takahashi JS, Lipp HP, Nakanishi S, Wehner JM, Giese KP, Tully T, Abel T, Chapman PF, Fox K, Grant S, Itohara S, Lathe R, Mayford M, et al. Mutant mice and neuroscience: Recommendations concerning genetic background Neuron. 19: 755-759. PMID 9354323 DOI: 10.1016/S0896-6273(00)80958-7  1
1997 Itoh T, Ikeda T, Gomi H, Nakao S, Suzuki T, Itohara S. Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice. The Journal of Biological Chemistry. 272: 22389-92. PMID 9278386 DOI: 10.1074/jbc.272.36.22389  1
1996 Shibuki K, Gomi H, Chen L, Bao S, Kim JJ, Wakatsuki H, Fujisaki T, Fujimoto K, Katoh A, Ikeda T, Chen C, Thompson RF, Itohara S. Deficient cerebellar long-term depression, impaired eyeblink conditioning, and normal motor coordination in GFAP mutant mice. Neuron. 16: 587-99. PMID 8785056 DOI: 10.1016/S0896-6273(00)80078-1  1
1996 Shiohara T, Moriya N, Hayakawa J, Itohara S, Ishikawa H. Resistance to cutaneous graft-vs.-host disease is not induced in T cell receptor delta gene-mutant mice. The Journal of Experimental Medicine. 183: 1483-9. PMID 8666906 DOI: 10.1084/jem.183.4.1483  1
1996 Yokoyama T, Itohara S, Yuasa N. Detection of species specific epitopes of mouse and hamster prion proteins (PrPs) by anti-peptide antibodies. Archives of Virology. 141: 763-9. PMID 8645112  1
1995 Itohara S. [Gamma delta T cells--gene to biology]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 40: 2118-25. PMID 8532867  1
1995 Gomi H, Yokoyama T, Fujimoto K, Ikeda T, Katoh A, Itoh T, Itohara S. Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions. Neuron. 14: 29-41. PMID 7826639 DOI: 10.1016/0896-6273(95)90238-4  1
1995 Emoto M, Nishimura H, Sakai T, Hiromatsu K, Gomi H, Itohara S, Yoshikai Y. Mice deficient in gamma delta T cells are resistant to lethal infection with Salmonella choleraesuis. Infection and Immunity. 63: 3736-8. PMID 7642318  1
1995 Komano H, Fujiura Y, Kawaguchi M, Matsumoto S, Hashimoto Y, Obana S, Mombaerts P, Tonegawa S, Yamamoto H, Itohara S. Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 6147-51. PMID 7597094 DOI: 10.1073/pnas.92.13.6147  1
1995 Nishimura H, Emoto M, Hiromatsu K, Yamamoto S, Matsuura K, Gomi H, Ikeda T, Itohara S, Yoshikai Y. The role of gamma delta T cells in priming macrophages to produce tumor necrosis factor-alpha. European Journal of Immunology. 25: 1465-8. PMID 7539762 DOI: 10.1002/eji.1830250551  1
1994 Gomi H, Ikeda T, Kunieda T, Itohara S, Prusiner SB, Yamanouchi K. Prion protein (PrP) is not involved in the pathogenesis of spongiform encephalopathy in zitter rats. Neuroscience Letters. 166: 171-4. PMID 7909925 DOI: 10.1016/0304-3940(94)90478-2  1
1994 Takahama Y, Hasegawa T, Itohara S, Ball EL, Sheard MA, Hashimoto Y. Entry of CD4-CD8- immature thymocytes into the CD4/CD8 developmental pathway is controlled by tyrosine kinase signals that can be provided through TCR components. International Immunology. 6: 1505-14. PMID 7826942 DOI: 10.1093/intimm/6.10.1505  1
1993 Itohara S, Mombaerts P, Lafaille J, Iacomini J, Nelson A, Clarke AR, Hooper ML, Farr A, Tonegawa S. T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes. Cell. 72: 337-48. PMID 8381716 DOI: 10.1016/0092-8674(93)90112-4  1
1992 Mombaerts P, Clarke AR, Rudnicki MA, Iacomini J, Itohara S, Lafaille JJ, Wang L, Ichikawa Y, Jaenisch R, Hooper ML. Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages. Nature. 360: 225-31. PMID 1359428 DOI: 10.1038/360225a0  1
1992 Mombaerts P, Clarke AR, Rudnicki MA, Iacomini J, Itohara S, Lafaille JJ, Wang L, Ichikawa Y, Jaenisch R, Hooper ML, Tonegawa S. Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages Nature. 360: X-231.  1
1991 Bandeira A, Itohara S, Bonneville M, Burlen-Defranoux O, Mota-Santos T, Coutinho A, Tonegawa S. Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta. Proceedings of the National Academy of Sciences of the United States of America. 88: 43-7. PMID 1986381  1
1991 Tonegawa S, Berns A, Bonneville M, Farr AG, Ishida I, Ito K, Itohara S, Janeway CA, Kanagawa O, Kubo R. Diversity, development, ligands, and probable functions of gamma delta T cells. Advances in Experimental Medicine and Biology. 292: 53-61. PMID 1835263  1
1991 Wu M, van Kaer L, Itohara S, Tonegawa S. Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells. The Journal of Experimental Medicine. 174: 213-8. PMID 1711563  1
1990 Ishida I, Verbeek S, Bonneville M, Itohara S, Berns A, Tonegawa S. T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 3067-71. PMID 2326267  1
1990 Bonneville M, Ishida I, Itohara S, Verbeek S, Berns A, Kanagawa O, Haas W, Tonegawa S. Self-tolerance to transgenic gamma delta T cells by intrathymic inactivation. Nature. 344: 163-5. PMID 2308634 DOI: 10.1038/344163a0  1
1990 Itohara S, Tonegawa S. Selection of gamma delta T cells with canonical T-cell antigen receptors in fetal thymus. Proceedings of the National Academy of Sciences of the United States of America. 87: 7935-8. PMID 2236011  1
1990 Itohara S, Farr AG, Lafaille JJ, Bonneville M, Takagaki Y, Haas W, Tonegawa S. Homing of a gamma delta thymocyte subset with homogeneous T-cell receptors to mucosal epithelia. Nature. 343: 754-7. PMID 2154700 DOI: 10.1038/343754a0  1
1990 Bandeira A, Mota-Santos T, Itohara S, Degermann S, Heusser C, Tonegawa S, Coutinho A. Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization. The Journal of Experimental Medicine. 172: 239-44. PMID 2141628  1
1990 Farr A, Hosier S, Nelson A, Itohara S, Tonegawa S. Distribution of thymocytes expressing gamma delta receptors in the murine thymus during development. Journal of Immunology (Baltimore, Md. : 1950). 144: 492-8. PMID 2136893  1
1990 Bonneville M, Itohara S, Krecko EG, Mombaerts P, Ishida I, Katsuki M, Berns A, Farr AG, Janeway CA, Tonegawa S. Transgenic mice demonstrate that epithelial homing of gamma/delta T cells is determined by cell lineages independent of T cell receptor specificity. The Journal of Experimental Medicine. 171: 1015-26. PMID 2109035  1
1989 Bonneville M, Ito K, Krecko EG, Itohara S, Kappes D, Ishida I, Kanagawa O, Janeway CA, Murphy DB, Tonegawa S. Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors. Proceedings of the National Academy of Sciences of the United States of America. 86: 5928-32. PMID 2788280 DOI: 10.1073/pnas.86.15.5928  1
1989 Itohara S, Nakanishi N, Kanagawa O, Kubo R, Tonegawa S. Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs. Proceedings of the National Academy of Sciences of the United States of America. 86: 5094-8. PMID 2787028  1
1989 Kono Y, Itohara S, Muramatsu S, Sentsui H, Ishino S, Sekikawa K. Characteristics of lymphocytes appearing in persistent lymphocytosis induced experimentally in cattle by bovine leukemia virus infection. Nihon Juigaku Zasshi. the Japanese Journal of Veterinary Science. 51: 70-8. PMID 2538673  1
1989 Tonegawa S, Berns A, Bonneville M, Farr A, Ishida I, Ito K, Itohara S, Janeway CA, Kanagawa O, Katsuki M. Diversity, development, ligands, and probable functions of gamma delta T cells. Cold Spring Harbor Symposia On Quantitative Biology. 54: 31-44. PMID 2534795  1
1989 Minoprio P, Itohara S, Heusser C, Tonegawa S, Coutinho A. Immunobiology of murine T. cruzi infection: the predominance of parasite-nonspecific responses and the activation of TCRI T cells. Immunological Reviews. 112: 183-207. PMID 2514135  1
1988 Sentsui H, Kono Y, Itohara S, Ishino S. Experimental infection of bovine leukemia virus in small laboratory animals. Nihon Juigaku Zasshi. the Japanese Journal of Veterinary Science. 50: 1245-51. PMID 2854587  1
1988 Itohara S, Tomiyama T, Ushimi C, Sekikawa K. Cooperative regulation of bovine leukaemia virus gene expression by two overlapping open reading frames in the XBL region. The Journal of General Virology. 69: 797-804. PMID 2833566  1
1987 Itohara S, Sekikawa K. Molecular cloning of infectious proviral genomes of bovine leukemia virus. Virology. 159: 158-60. PMID 3037775 DOI: 10.1016/0042-6822(87)90359-X  1
1987 Itohara S, Sekikawa K, Mizuno Y, Kono Y, Nakajima H. Establishment of bovine leukemia virus-producing and -nonproducing B-lymphoid cell lines and their proviral genomes. Leukemia Research. 11: 407-14. PMID 3033403 DOI: 10.1016/0145-2126(87)90071-3  1
1986 Koyama H, Imamura Y, Yoshikawa H, Kajikawa O, Itohara S, Mizuno Y, Yoshikawa T, Saito H. Establishment of a continuous cell line derived from leukaemic cattle. Zentralblatt FüR VeterinäRmedizin. Reihe B. Journal of Veterinary Medicine. Series B. 33: 586-96. PMID 3026121  1
1986 Mizuno Y, Itohara S. Enzyme-linked immunosorbent assay to detect subgroup-specific antibodies to avian leukosis viruses. American Journal of Veterinary Research. 47: 551-6. PMID 3008600  1
1986 Kono Y, Arai K, Sentsui H, Matsukawa S, Itohara S. Protection against bovine leukemia virus infection in sheep by active and passive immunization. Nihon Juigaku Zasshi. the Japanese Journal of Veterinary Science. 48: 117-25. PMID 3007840  1
1985 Itohara S, Oikawa I, Terui S, Mizuno Y. Infectivities of bovine leukemia virus in peripheral blood lymphocytes from naturally infected cattle and their relation to persistent lymphocytosis and antibody titers. Nihon Juigaku Zasshi. the Japanese Journal of Veterinary Science. 47: 807-10. PMID 2999495  1
1984 Itohara S, Mizuno Y. Dimethyl sulfoxide enhances syncytium formation induced by bovine leukemia virus. Microbiology and Immunology. 28: 251-5. PMID 6328232  1
1982 Itohara S, Takatori I. Syncytia infectivity of assay of bovine leukemia virus. National Institute of Animal Health Quarterly. 22: 147-53. PMID 6312331  1
1982 Takatori I, Itohara S, Yonaiyama K. Difficulty in detecting in vivo extracellular infective virus in cattle naturally infected with bovine leukemia virus. Leukemia Research. 6: 511-7. PMID 6292585 DOI: 10.1016/0145-2126(82)90008-X  1
1980 Ogawa T, Sugimura T, Itohara S, Tanaka Y, Kumagai T. Intracerebral pathogenicity of influenza A viruses for chickens. Archives of Virology. 64: 383-6. PMID 7396726 DOI: 10.1007/BF01320623  1
1978 Itohara S, Hirata K, Inoue M, Hatsuoka M, Sato A. Isolation of a sarcoma virus from a spontaneous chicken tumor. Gan. 69: 825-30. PMID 220128  1
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