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Hans Lehrach - Publications

Affiliations: 
Vertebrate Genomics Max Planck Institute for Molecular Genetics, Berlin, Berlin, Germany 
Website:
http://www.molgen.mpg.de/research/lehrach/
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Year Citation  Score
2017 Rykalina V, Shadrin A, Lehrach H, Borodina T. qPCR-based characterization of DNA fragmentation efficiency of Tn5 transposomes. Biology Methods & Protocols. 2: bpx001. PMID 32161784 DOI: 10.1093/Biomethods/Bpx001  0.306
2016 Broecker F, Horton R, Heinrich J, Franz A, Schweiger MR, Lehrach H, Moelling K. The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation. Mobile Dna. 7: 25. PMID 27980690 DOI: 10.1186/S13100-016-0081-9  0.32
2016 Bender S, Gronych J, Warnatz H, Hutter B, Gröbner S, Ryzhova M, Pfaff E, Hovestadt V, Weinberg F, Halbach S, Kool M, Northcott PA, Sturm D, Bjerke L, Zichner T, ... ... Lehrach H, et al. Recurrent MET fusion genes represent a drug target in pediatric glioblastoma Nature Medicine. 22: 1314-1320. PMID 27748748 DOI: 10.1038/Nm.4204  0.321
2016 Mertes F, Kuhl H, Wruck W, Lehrach H, Adjaye J. Combined sequencing of mRNA and DNA from human embryonic stem cells. Genomics Data. 8: 131-3. PMID 27275414 DOI: 10.1016/J.Gdata.2016.04.014  0.343
2015 Mertes F, Lichtner B, Kuhl H, Blattner M, Otte J, Wruck W, Timmermann B, Lehrach H, Adjaye J. Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells. Bmc Genomics. 16: 925. PMID 26564201 DOI: 10.1186/S12864-015-2025-Z  0.343
2015 Fischer U, Forster M, Rinaldi A, Risch T, Sungalee S, Warnatz HJ, Bornhauser B, Gombert M, Kratsch C, Stütz AM, Sultan M, Tchinda J, Worth CL, Amstislavskiy V, Badarinarayan N, ... ... Lehrach H, et al. Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. Nature Genetics. PMID 26214592 DOI: 10.1038/Ng.3362  0.306
2015 Regan JL, Schumacher D, Staudte S, Boehnke K, Keilholz U, Haybaeck J, Lehrach H, Henderson D, Schaefer R, Regenbrecht CR, Mumberg D, Lange M. Abstract 977: 3D-models of patient-derived colon tumors for the identification of genetic factors important in the regulation of cancer stem cells Cancer Research. 75: 977-977. DOI: 10.1158/1538-7445.Am2015-977  0.325
2015 Lin CY, Erkek S, Tong Y, Yang L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz H, Worst B, Ju B, Orr BA, Zeid R, Polaski DR, ... ... Lehrach H, et al. Abstract LB-B23: Medulloblastoma regulatory circuitries reveal subgroup-specific cellular origins Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Lb-B23  0.308
2014 Hoehe MR, Church GM, Lehrach H, Kroslak T, Palczewski S, Nowick K, Schulz S, Suk EK, Huebsch T. Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes. Nature Communications. 5: 5569. PMID 25424553 DOI: 10.1038/Ncomms6569  0.371
2014 Rykalina VN, Shadrin AA, Amstislavskiy VS, Rogaev EI, Lehrach H, Borodina TA. Exome sequencing from nanogram amounts of starting DNA: comparing three approaches. Plos One. 9: e101154. PMID 24992588 DOI: 10.1371/Journal.Pone.0101154  0.332
2014 Rasche A, Lienhard M, Yaspo ML, Lehrach H, Herwig R. ARH-seq: identification of differential splicing in RNA-seq data. Nucleic Acids Research. 42: e110. PMID 24920826 DOI: 10.1093/Nar/Gku495  0.326
2014 Hovestadt V, Jones DT, Picelli S, Wang W, Kool M, Northcott PA, Sultan M, Stachurski K, Ryzhova M, Warnatz HJ, Ralser M, Brun S, Bunt J, Jäger N, Kleinheinz K, ... ... Lehrach H, et al. Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature. 510: 537-41. PMID 24847876 DOI: 10.1038/Nature13268  0.355
2014 Rashi-Elkeles S, Warnatz HJ, Elkon R, Kupershtein A, Chobod Y, Paz A, Amstislavskiy V, Sultan M, Safer H, Nietfeld W, Lehrach H, Shamir R, Yaspo ML, Shiloh Y. Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation. Science Signaling. 7: rs3. PMID 24825921 DOI: 10.1126/Scisignal.2005032  0.339
2014 Hussong M, Börno ST, Kerick M, Wunderlich A, Franz A, Sültmann H, Timmermann B, Lehrach H, Hirsch-Kauffmann M, Schweiger MR. The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. Cell Death & Disease. 5: e1195. PMID 24763052 DOI: 10.1038/Cddis.2014.157  0.305
2014 Dohm JC, Minoche AE, Holtgräwe D, Capella-Gutiérrez S, Zakrzewski F, Tafer H, Rupp O, Sörensen TR, Stracke R, Reinhardt R, Goesmann A, Kraft T, Schulz B, Stadler PF, Schmidt T, ... ... Lehrach H, et al. The genome of the recently domesticated crop plant sugar beet (Beta vulgaris). Nature. 505: 546-9. PMID 24352233 DOI: 10.1038/Nature12817  0.342
2014 Regan JL, Schumacher D, Boehnke K, Davies C, Keilholz U, Haybaeck J, Reinhard C, Lehrach H, Henderson D, Schaefer R, Regenbrecht C, Lange M. Abstract 3875: Functional and molecular characterization of colon cancer stem cells in tumor heterogeneity and disease relapse using a 3D-model of patient-derived tumors Cancer Research. 74: 3875-3875. DOI: 10.1158/1538-7445.Am2014-3875  0.301
2013 Jäger N, Schlesner M, Jones DT, Raffel S, Mallm JP, Junge KM, Weichenhan D, Bauer T, Ishaque N, Kool M, Northcott PA, Korshunov A, Drews RM, Koster J, Versteeg R, ... ... Lehrach H, et al. Hypermutation of the inactive X chromosome is a frequent event in cancer. Cell. 155: 567-81. PMID 24139898 DOI: 10.1016/J.Cell.2013.09.042  0.322
2013 Lehrach H. DNA sequencing methods in human genetics and disease research. F1000prime Reports. 5: 34. PMID 24049638 DOI: 10.12703/P5-34  0.319
2013 Lappalainen T, Sammeth M, Friedländer MR, 't Hoen PA, Monlong J, Rivas MA, Gonzàlez-Porta M, Kurbatova N, Griebel T, Ferreira PG, Barann M, Wieland T, Greger L, van Iterson M, Almlöf J, ... ... Lehrach H, et al. Transcriptome and genome sequencing uncovers functional variation in humans. Nature. 501: 506-11. PMID 24037378 DOI: 10.1038/Nature12531  0.341
2013 Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, ... ... Lehrach H, et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Genetics. 45: 927-32. PMID 23817572 DOI: 10.1038/Ng.2682  0.308
2013 Barann M, Esser D, Klostermeier UC, Lappalainen T, Luzius A, Kuiper JW, Ammerpohl O, Vater I, Siebert R, Amstislavskiy V, Sudbrak R, Lehrach H, Schreiber S, Rosenstiel P. Janus--a comprehensive tool investigating the two faces of transcription. Bioinformatics (Oxford, England). 29: 1600-6. PMID 23620359 DOI: 10.1093/Bioinformatics/Btt185  0.336
2013 Fogeron ML, Müller H, Schade S, Dreher F, Lehmann V, Kühnel A, Scholz AK, Kashofer K, Zerck A, Fauler B, Lurz R, Herwig R, Zatloukal K, Lehrach H, Gobom J, et al. LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Nature Communications. 4: 1531. PMID 23443559 DOI: 10.1038/Ncomms2517  0.31
2013 Zazzu V, Regierer B, Kühn A, Sudbrak R, Lehrach H. IT Future of Medicine: from molecular analysis to clinical diagnosis and improved treatment. New Biotechnology. 30: 362-5. PMID 23165094 DOI: 10.1016/J.Nbt.2012.11.002  0.309
2013 Lienhard M, Chavez L, Grimm C, Morkel M, Lehrach H, Schweiger M, Herwig R. Individual genomic variations as determinants for DNA methylation and gene expression changes in cancer F1000research. 4. DOI: 10.7490/F1000Research.1094120.1  0.34
2012 Ralser M, Kuhl H, Ralser M, Werber M, Lehrach H, Breitenbach M, Timmermann B. The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt. Open Biology. 2: 120093. PMID 22977733 DOI: 10.1098/Rsob.120093  0.324
2012 van Delft J, Gaj S, Lienhard M, Albrecht MW, Kirpiy A, Brauers K, Claessen S, Lizarraga D, Lehrach H, Herwig R, Kleinjans J. RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene. Toxicological Sciences : An Official Journal of the Society of Toxicology. 130: 427-39. PMID 22889811 DOI: 10.1093/Toxsci/Kfs250  0.34
2012 Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, ... ... Lehrach H, et al. Dissecting the genomic complexity underlying medulloblastoma. Nature. 488: 100-5. PMID 22832583 DOI: 10.1038/Nature11284  0.333
2012 Querfurth R, Fischer A, Schweiger MR, Lehrach H, Mertes F. Creation and application of immortalized bait libraries for targeted enrichment and next-generation sequencing. Biotechniques. 52: 375-80. PMID 22668416 DOI: 10.2144/0000113877  0.327
2012 Welzel F, Kaehler C, Isau M, Hallen L, Lehrach H, Krobitsch S. FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpression. Plos One. 7: e37985. PMID 22666429 DOI: 10.1371/Journal.Pone.0037985  0.341
2012 Kamburov A, Galicka H, Lehrach H, Herwig R. ConsensusPathDB: assembling a more complete picture of cell biology F1000research. 3. DOI: 10.7490/F1000Research.1092194.1  0.326
2012 Kühn A, Lehrach H. The "Virtual Patient" system: Modeling cancer using deep sequencing technologies for personalized cancer treatment Journal Fur Verbraucherschutz Und Lebensmittelsicherheit. 7: 55-62. DOI: 10.1007/S00003-011-0755-7  0.31
2011 Göke J, Jung M, Behrens S, Chavez L, O'Keeffe S, Timmermann B, Lehrach H, Adjaye J, Vingron M. Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development. Plos Computational Biology. 7: e1002304. PMID 22215994 DOI: 10.1371/Journal.Pcbi.1002304  0.307
2011 Mertes F, Elsharawy A, Sauer S, van Helvoort JM, van der Zaag PJ, Franke A, Nilsson M, Lehrach H, Brookes AJ. Targeted enrichment of genomic DNA regions for next-generation sequencing. Briefings in Functional Genomics. 10: 374-86. PMID 22121152 DOI: 10.1093/Bfgp/Elr033  0.309
2011 Bormann F, Sers C, Seliger B, Handke D, Bergmann T, Seibt S, Lehrach H, Dahl A. Methylation-specific ligation detection reaction (msLDR): a new approach for multiplex evaluation of methylation patterns. Molecular Genetics and Genomics : Mgg. 286: 279-91. PMID 21879293 DOI: 10.1007/S00438-011-0645-9  0.309
2011 Vilardell M, Rasche A, Thormann A, Maschke-Dutz E, Pérez-Jurado LA, Lehrach H, Herwig R. Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes. Bmc Genomics. 12: 229. PMID 21569303 DOI: 10.1186/1471-2164-12-229  0.38
2011 Warnatz HJ, Schmidt D, Manke T, Piccini I, Sultan M, Borodina T, Balzereit D, Wruck W, Soldatov A, Vingron M, Lehrach H, Yaspo ML. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. The Journal of Biological Chemistry. 286: 23521-32. PMID 21555518 DOI: 10.1074/Jbc.M111.220178  0.35
2011 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, ... ... Lehrach H, et al. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Plos Biology. 9: e1000582. PMID 21267068 DOI: 10.1371/Journal.Pbio.1000582  0.379
2011 Lim TS, Schütze T, Lehrach H, Glökler J, Konthur Z. Diversity visualization by endonuclease: a rapid assay to monitor diverse nucleotide libraries. Analytical Biochemistry. 411: 16-21. PMID 21185254 DOI: 10.1016/J.Ab.2010.12.024  0.303
2011 Kamburov A, Pentchev K, Galicka H, Wierling C, Lehrach H, Herwig R. ConsensusPathDB: toward a more complete picture of cell biology. Nucleic Acids Research. 39: D712-7. PMID 21071422 DOI: 10.1093/Nar/Gkq1156  0.307
2011 Hallen L, Klein H, Stoschek C, Wehrmeyer S, Nonhoff U, Ralser M, Wilde J, Röhr C, Schweiger MR, Zatloukal K, Vingron M, Lehrach H, Konthur Z, Krobitsch S. The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. Human Molecular Genetics. 20: 104-14. PMID 20926453 DOI: 10.1093/Hmg/Ddq436  0.31
2010 Boerno ST, Grimm C, Lehrach H, Schweiger MR. Next-generation sequencing technologies for DNA methylation analyses in cancer genomics. Epigenomics. 2: 199-207. PMID 22121870 DOI: 10.2217/Epi.09.50  0.314
2010 Denoeud F, Henriet S, Mungpakdee S, Aury JM, Da Silva C, Brinkmann H, Mikhaleva J, Olsen LC, Jubin C, Cañestro C, Bouquet JM, Danks G, Poulain J, Campsteijn C, Adamski M, ... ... Lehrach H, et al. Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate. Science (New York, N.Y.). 330: 1381-5. PMID 21097902 DOI: 10.1126/Science.1194167  0.32
2010 Wolfrum K, Wang Y, Prigione A, Sperling K, Lehrach H, Adjaye J. The LARGE principle of cellular reprogramming: lost, acquired and retained gene expression in foreskin and amniotic fluid-derived human iPS cells. Plos One. 5: e13703. PMID 21060825 DOI: 10.1371/Journal.Pone.0013703  0.337
2010 Müller H, Schmidt D, Steinbrink S, Mirgorodskaya E, Lehmann V, Habermann K, Dreher F, Gustavsson N, Kessler T, Lehrach H, Herwig R, Gobom J, Ploubidou A, Boutros M, Lange BM. Proteomic and functional analysis of the mitotic Drosophila centrosome. The Embo Journal. 29: 3344-57. PMID 20818332 DOI: 10.1038/Emboj.2010.210  0.321
2010 Chavez L, Jozefczuk J, Grimm C, Dietrich J, Timmermann B, Lehrach H, Herwig R, Adjaye J. Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage. Genome Research. 20: 1441-50. PMID 20802089 DOI: 10.1101/Gr.110114.110  0.318
2010 Jung M, Peterson H, Chavez L, Kahlem P, Lehrach H, Vilo J, Adjaye J. A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells. Plos One. 5: e10709. PMID 20505756 DOI: 10.1371/Journal.Pone.0010709  0.321
2010 Warnatz HJ, Querfurth R, Guerasimova A, Cheng X, Haas SA, Hufton AL, Manke T, Vanhecke D, Nietfeld W, Vingron M, Janitz M, Lehrach H, Yaspo ML. Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters. Nucleic Acids Research. 38: 6112-23. PMID 20494980 DOI: 10.1093/Nar/Gkq402  0.338
2010 Hu Y, Lehrach H, Janitz M. Apoptosis screening of human chromosome 21 proteins reveals novel cell death regulators. Molecular Biology Reports. 37: 3381-7. PMID 20091128 DOI: 10.1007/S11033-009-9926-3  0.356
2010 Lim TS, Mollova S, Rubelt F, Sievert V, Dübel S, Lehrach H, Konthur Z. V-gene amplification revisited - An optimised procedure for amplification of rearranged human antibody genes of different isotypes. New Biotechnology. 27: 108-17. PMID 20083243 DOI: 10.1016/J.Nbt.2010.01.001  0.321
2010 Galiveti CR, Rozhdestvensky TS, Brosius J, Lehrach H, Konthur Z. Application of housekeeping npcRNAs for quantitative expression analysis of human transcriptome by real-time PCR. Rna (New York, N.Y.). 16: 450-61. PMID 20040593 DOI: 10.1261/Rna.1755810  0.346
2010 Jozefczuk J, Stachelscheid H, Chavez L, Herwig R, Lehrach H, Zeilinger K, Gerlach JC, Adjaye J. Molecular characterization of cultured adult human liver progenitor cells. Tissue Engineering. Part C, Methods. 16: 821-34. PMID 19874131 DOI: 10.1089/Ten.Tec.2009.0578  0.32
2010 Cheng X, Guerasimova A, Manke T, Rosenstiel P, Haas S, Warnatz HJ, Querfurth R, Nietfeld W, Vanhecke D, Lehrach H, Yaspo ML, Janitz M. Screening of human gene promoter activities using transfected-cell arrays. Gene. 450: 48-54. PMID 19840836 DOI: 10.1016/J.Gene.2009.10.003  0.333
2009 Hu Y, Lehrach H, Janitz M. Comparative analysis of an experimental subcellular protein localization assay and in silico prediction methods. Journal of Molecular Histology. 40: 343-52. PMID 20033263 DOI: 10.1007/S10735-009-9247-9  0.344
2009 Mertes F, Martinez-Morales JR, Nolden T, Spörle R, Wittbrodt J, Lehrach H, Himmelbauer H. Cloning of mouse ojoplano, a reticular cytoplasmic protein expressed during embryonic development. Gene Expression Patterns : Gep. 9: 562-7. PMID 19766735 DOI: 10.1016/J.Gep.2009.09.003  0.344
2009 Hufton AL, Mathia S, Braun H, Georgi U, Lehrach H, Vingron M, Poustka AJ, Panopoulou G. Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention. Genome Research. 19: 2036-51. PMID 19704032 DOI: 10.1101/Gr.093237.109  0.375
2009 Schweiger MR, Kerick M, Timmermann B, Albrecht MW, Borodina T, Parkhomchuk D, Zatloukal K, Lehrach H. Genome-wide massively parallel sequencing of formaldehyde fixed-paraffin embedded (FFPE) tumor tissues for copy-number- and mutation-analysis. Plos One. 4: e5548. PMID 19440246 DOI: 10.1371/Journal.Pone.0005548  0.323
2009 Bíliková K, Mirgorodskaya E, Bukovská G, Gobom J, Lehrach H, Simúth J. Towards functional proteomics of minority component of honeybee royal jelly: the effect of post-translational modifications on the antimicrobial activity of apalbumin2. Proteomics. 9: 2131-8. PMID 19322786 DOI: 10.1002/Pmic.200800705  0.312
2008 Regenbrecht C, Welte Y, Jodicke A, Hugel R, Walden P, Jung M, Lehrach H, Adjaye J. Molecular characterization of signalling pathways in cancer stem cells. Ecancermedicalscience. 2: 115. PMID 22275988 DOI: 10.3332/Ecancer.2008.115  0.301
2008 Kues WA, Sudheer S, Herrmann D, Carnwath JW, Havlicek V, Besenfelder U, Lehrach H, Adjaye J, Niemann H. Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 19768-73. PMID 19064908 DOI: 10.1073/Pnas.0805616105  0.336
2008 Regenbrecht CR, Jung M, Lehrach H, Adjaye J. The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines. Bmc Medical Genomics. 1: 49. PMID 18847459 DOI: 10.1186/1755-8794-1-49  0.3
2008 Sultan M, Schulz MH, Richard H, Magen A, Klingenhoff A, Scherf M, Seifert M, Borodina T, Soldatov A, Parkhomchuk D, Schmidt D, O'Keeffe S, Haas S, Vingron M, Lehrach H, et al. A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. Science (New York, N.Y.). 321: 956-60. PMID 18599741 DOI: 10.1126/Science.1160342  0.376
2008 Ralser M, Nebel A, Kleindorp R, Krobitsch S, Lehrach H, Schreiber S, Reinhardt R, Timmermann B. Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans. Bmc Genetics. 9: 38. PMID 18510744 DOI: 10.1186/1471-2156-9-38  0.311
2008 Fiebitz A, Nyarsik L, Haendler B, Hu YH, Wagner F, Thamm S, Lehrach H, Janitz M, Vanhecke D. High-throughput mammalian two-hybrid screening for protein-protein interactions using transfected cell arrays. Bmc Genomics. 9: 68. PMID 18254948 DOI: 10.1186/1471-2164-9-68  0.357
2008 Lehrach H. Gene sequencing and expression profiles in diagnosis and prognosis | Gen-sequenzierung und expressionsprofile in diagnostik und prognose Journal Fur Verbraucherschutz Und Lebensmittelsicherheit. 3: 47-48. DOI: 10.1007/S00003-008-0315-Y  0.324
2007 Adjaye J, Herwig R, Brink TC, Herrmann D, Greber B, Sudheer S, Groth D, Carnwath JW, Lehrach H, Niemann H. Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression. Physiological Genomics. 31: 315-27. PMID 17595343 DOI: 10.1152/Physiolgenomics.00041.2007  0.372
2007 Sultan M, Piccini I, Balzereit D, Herwig R, Saran NG, Lehrach H, Reeves RH, Yaspo ML. Gene expression variation in Down's syndrome mice allows prioritization of candidate genes. Genome Biology. 8: R91. PMID 17531092 DOI: 10.1186/Gb-2007-8-5-R91  0.328
2007 Poustka AJ, Kühn A, Groth D, Weise V, Yaguchi S, Burke RD, Herwig R, Lehrach H, Panopoulou G. A global view of gene expression in lithium and zinc treated sea urchin embryos: new components of gene regulatory networks. Genome Biology. 8: R85. PMID 17506889 DOI: 10.1186/Gb-2007-8-5-R85  0.338
2007 Liu JP, Drungowski M, Nyársik L, Schwartz R, Lehrach H, Herwig R, Janitz M. Oligonucleotide fingerprinting of arrayed genomic DNA sequences using LNA-modified hybridization probes. Combinatorial Chemistry & High Throughput Screening. 10: 269-76. PMID 17506710 DOI: 10.2174/138620707780636637  0.325
2007 Purmann A, Toedling J, Schueler M, Carninci P, Lehrach H, Hayashizaki Y, Huber W, Sperling S. Genomic organization of transcriptomes in mammals: Coregulation and cofunctionality. Genomics. 89: 580-7. PMID 17369017 DOI: 10.1016/J.Ygeno.2007.01.010  0.328
2007 Bennett JT, Joubin K, Cheng S, Aanstad P, Herwig R, Clark M, Lehrach H, Schier AF. Nodal signaling activates differentiation genes during zebrafish gastrulation. Developmental Biology. 304: 525-40. PMID 17306247 DOI: 10.1016/J.Ydbio.2007.01.012  0.345
2007 Nordhoff E, Lehrach H. Identification and characterization of DNA-binding proteins by mass spectrometry. Advances in Biochemical Engineering/Biotechnology. 104: 111-95. PMID 17290821 DOI: 10.1007/10_2006_037  0.306
2007 Dahl A, Sultan M, Jung A, Schwartz R, Lange M, Steinwand M, Livak KJ, Lehrach H, Nyarsik L. Quantitative PCR based expression analysis on a nanoliter scale using polymer nano-well chips. Biomedical Microdevices. 9: 307-14. PMID 17203381 DOI: 10.1007/S10544-006-9034-2  0.335
2007 Babaie Y, Herwig R, Greber B, Brink TC, Wruck W, Groth D, Lehrach H, Burdon T, Adjaye J. Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells (Dayton, Ohio). 25: 500-10. PMID 17068183 DOI: 10.1634/Stemcells.2006-0426  0.332
2006 Makrantonaki E, Adjaye J, Herwig R, Brink TC, Groth D, Hultschig C, Lehrach H, Zouboulis CC. Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro. Aging Cell. 5: 331-44. PMID 16805856 DOI: 10.1111/J.1474-9726.2006.00223.X  0.304
2006 Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem P, Lehrach H, Yaspo ML, Janitz M. Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. Bmc Genomics. 7: 155. PMID 16780588 DOI: 10.1186/1471-2164-7-155  0.395
2006 Gebert C, Wrenzycki C, Herrmann D, Gröger D, Reinhardt R, Hajkova P, Lucas-Hahn A, Carnwath J, Lehrach H, Niemann H. The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA. Genomics. 88: 222-9. PMID 16644179 DOI: 10.1016/J.Ygeno.2006.03.011  0.328
2006 Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, ... ... Lehrach H, et al. The DNA sequence, annotation and analysis of human chromosome 3. Nature. 440: 1194-8. PMID 16641997 DOI: 10.1038/Nature04728  0.362
2006 Janitz M, Vanhecke D, Lehrach H. High-throughput RNA interference in functional genomics. Handbook of Experimental Pharmacology. 97-104. PMID 16594612 DOI: 10.1007/3-540-27262-3_5  0.328
2006 Horn S, Lueking A, Murphy D, Staudt A, Gutjahr C, Schulte K, König A, Landsberger M, Lehrach H, Felix SB, Cahill DJ. Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease-associated protein chip. Proteomics. 6: 605-13. PMID 16419013 DOI: 10.1002/Pmic.200401293  0.313
2006 Hultschig C, Kreutzberger J, Seitz H, Konthur Z, Büssow K, Lehrach H. Recent advances of protein microarrays. Current Opinion in Chemical Biology. 10: 4-10. PMID 16376134 DOI: 10.1016/J.Cbpa.2005.12.011  0.308
2006 Weichart D, Gobom J, Klopfleisch S, Häsler R, Gustavsson N, Billmann S, Lehrach H, Seegert D, Schreiber S, Rosenstiel P. Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells. The Journal of Biological Chemistry. 281: 2380-9. PMID 16257953 DOI: 10.1074/Jbc.M505986200  0.342
2005 Sauer S, Konthur Z, Lehrach H. Genome projects and the functional-genomic era. Combinatorial Chemistry & High Throughput Screening. 8: 659-67. PMID 16464154 DOI: 10.2174/138620705774962436  0.339
2005 Mirgorodskaya E, Wanker E, Otto A, Lehrach H, Gobom J. Method for qualitative comparisons of protein mixtures based on enzyme-catalyzed stable-isotope incorporation. Journal of Proteome Research. 4: 2109-16. PMID 16335956 DOI: 10.1021/Pr050219I  0.542
2005 Hu YH, Vanhecke D, Lehrach H, Janitz M. High-throughput subcellular protein localization using cell arrays. Biochemical Society Transactions. 33: 1407-8. PMID 16246131 DOI: 10.1042/Bst0331407  0.374
2005 Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, ... ... Lehrach H, et al. A human protein-protein interaction network: a resource for annotating the proteome. Cell. 122: 957-68. PMID 16169070 DOI: 10.1016/J.Cell.2005.08.029  0.562
2005 Gade D, Theiss D, Lange D, Mirgorodskaya E, Lombardot T, Glöckner FO, Kube M, Reinhardt R, Amann R, Lehrach H, Rabus R, Gobom J. Towards the proteome of the marine bacterium Rhodopirellula baltica: mapping the soluble proteins. Proteomics. 5: 3654-71. PMID 16127728 DOI: 10.1002/Pmic.200401201  0.366
2005 Ralser M, Goehler H, Wanker EE, Lehrach H, Krobitsch S. Generation of a yeast two-hybrid strain suitable for competitive protein binding analysis. Biotechniques. 39: 165-6, 168. PMID 16116786 DOI: 10.2144/05392BM01  0.527
2005 Ralser M, Nonhoff U, Albrecht M, Lengauer T, Wanker EE, Lehrach H, Krobitsch S. Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways. Human Molecular Genetics. 14: 2893-909. PMID 16115810 DOI: 10.1093/hmg/ddi321  0.517
2005 Costello CM, Mah N, Häsler R, Rosenstiel P, Waetzig GH, Hahn A, Lu T, Gurbuz Y, Nikolaus S, Albrecht M, Hampe J, Lucius R, Klöppel G, Eickhoff H, Lehrach H, et al. Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays. Plos Medicine. 2: e199. PMID 16107186 DOI: 10.1371/Journal.Pmed.0020199  0.302
2005 Adjaye J, Huntriss J, Herwig R, BenKahla A, Brink TC, Wierling C, Hultschig C, Groth D, Yaspo ML, Picton HM, Gosden RG, Lehrach H. Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells. Stem Cells (Dayton, Ohio). 23: 1514-25. PMID 16081659 DOI: 10.1634/Stemcells.2005-0113  0.331
2005 Feilner T, Hultschig C, Lee J, Meyer S, Immink RG, Koenig A, Possling A, Seitz H, Beveridge A, Scheel D, Cahill DJ, Lehrach H, Kreutzberger J, Kersten B. High throughput identification of potential Arabidopsis mitogen-activated protein kinases substrates. Molecular & Cellular Proteomics : McP. 4: 1558-68. PMID 16009969 DOI: 10.1074/Mcp.M500007-Mcp200  0.305
2005 Büssow K, Scheich C, Sievert V, Harttig U, Schultz J, Simon B, Bork P, Lehrach H, Heinemann U. Structural genomics of human proteins--target selection and generation of a public catalogue of expression clones. Microbial Cell Factories. 4: 21. PMID 15998469 DOI: 10.1186/1475-2859-4-21  0.353
2005 Lueking A, Huber O, Wirths C, Schulte K, Stieler KM, Blume-Peytavi U, Kowald A, Hensel-Wiegel K, Tauber R, Lehrach H, Meyer HE, Cahill DJ. Profiling of alopecia areata autoantigens based on protein microarray technology. Molecular & Cellular Proteomics : McP. 4: 1382-90. PMID 15939964 DOI: 10.1074/Mcp.T500004-Mcp200  0.345
2005 Sauer S, Lange BM, Gobom J, Nyarsik L, Seitz H, Lehrach H. Miniaturization in functional genomics and proteomics. Nature Reviews. Genetics. 6: 465-76. PMID 15931170 DOI: 10.1038/Nrg1618  0.334
2005 Steller S, Angenendt P, Cahill DJ, Heuberger S, Lehrach H, Kreutzberger J. Bacterial protein microarrays for identification of new potential diagnostic markers for Neisseria meningitidis infections. Proteomics. 5: 2048-55. PMID 15852346 DOI: 10.1002/Pmic.200401097  0.333
2005 Greber B, Tandara H, Lehrach H, Himmelbauer H. Comparison of PCR-based mutation detection methods and application for identification of mouse Sult1a1 mutant embryonic stem cell clones using pooled templates. Human Mutation. 25: 483-90. PMID 15832303 DOI: 10.1002/Humu.20168  0.323
2005 Giavalisco P, Wilson D, Kreitler T, Lehrach H, Klose J, Gobom J, Fucini P. High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome. Plant Molecular Biology. 57: 577-91. PMID 15821981 DOI: 10.1007/S11103-005-0699-3  0.313
2005 Greber B, Lehrach H, Himmelbauer H. Mouse splice mutant generation from ENU-treated ES cells--a gene-driven approach. Genomics. 85: 557-62. PMID 15820307 DOI: 10.1016/J.Ygeno.2005.01.011  0.346
2005 Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, ... ... Lehrach H, et al. The DNA sequence of the human X chromosome. Nature. 434: 325-37. PMID 15772651 DOI: 10.1038/Nature03440  0.318
2005 Gutjahr C, Murphy D, Lueking A, Koenig A, Janitz M, O'Brien J, Korn B, Horn S, Lehrach H, Cahill DJ. Mouse protein arrays from a TH1 cell cDNA library for antibody screening and serum profiling. Genomics. 85: 285-96. PMID 15718096 DOI: 10.1016/J.Ygeno.2004.11.005  0.367
2005 Bürkle L, Meyer S, Dortay H, Lehrach H, Heyl A. In vitro recombination cloning of entire cDNA libraries in Arabidopsis thaliana and its application to the yeast two-hybrid system. Functional & Integrative Genomics. 5: 175-83. PMID 15714319 DOI: 10.1007/S10142-005-0134-5  0.354
2005 Ralser M, Nonhoff U, Albrecht M, Lengauer T, Wanker E, Lehrach H, Krobitsch S. Functional association of the polyglutamine proteins ataxin-2 and huntingtin Gbm Annual Fall Meeting Berlin/Potsdam 2005. 2005. DOI: 10.1240/SAV_GBM_2005_H_001239  0.471
2005 Niesner U, Albrecht I, Baumgrass R, Janitz M, Lehrach H, Haeupl T, Grun J, Burmester G, Grutzkau A, Radbruch A. Arthritis Research & Therapy. 7: P90. DOI: 10.1186/Ar1611  0.313
2004 Edvardsen RB, Lerat E, Maeland AD, FlÃ¥t M, Tewari R, Jensen MF, Lehrach H, Reinhardt R, Seo HC, Chourrout D. Hypervariable and highly divergent intron-exon organizations in the chordate Oikopleura dioica. Journal of Molecular Evolution. 59: 448-57. PMID 15638456 DOI: 10.1007/S00239-004-2636-5  0.345
2004 Illiger J, Herwig R, Steinfath M, Przewieslik T, Elge T, Bull Ch, Radelof U, Lehrach H, Janitz M. Establishment of T cell-specific and natural killer cell-specific unigene sets: towards high-throughput genomics of leukaemia. European Journal of Immunogenetics : Official Journal of the British Society For Histocompatibility and Immunogenetics. 31: 253-7. PMID 15548262 DOI: 10.1111/J.1365-2370.2004.00483.X  0.326
2004 Adjaye J, Herwig R, Herrmann D, Wruck W, Benkahla A, Brink TC, Nowak M, Carnwath JW, Hultschig C, Niemann H, Lehrach H. Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays. Bmc Genomics. 5: 83. PMID 15511299 DOI: 10.1186/1471-2164-5-83  0.361
2004 Hilson P, Allemeersch J, Altmann T, Aubourg S, Avon A, Beynon J, Bhalerao RP, Bitton F, Caboche M, Cannoot B, Chardakov V, Cognet-Holliger C, Colot V, Crowe M, Darimont C, ... ... Lehrach H, et al. Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications. Genome Research. 14: 2176-89. PMID 15489341 DOI: 10.1101/Gr.2544504  0.392
2004 Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, Droege A, Lindenberg KS, Knoblich M, Haenig C, Herbst M, Suopanki J, Scherzinger E, Abraham C, Bauer B, ... ... Lehrach H, et al. A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. Molecular Cell. 15: 853-65. PMID 15383276 DOI: 10.1016/J.Molcel.2004.09.016  0.561
2004 Büssow K, Quedenau C, Sievert V, Tischer J, Scheich C, Seitz H, Hieke B, Niesen FH, Götz F, Harttig U, Lehrach H. A catalog of human cDNA expression clones and its application to structural genomics. Genome Biology. 5: R71. PMID 15345055 DOI: 10.1186/Gb-2004-5-9-R71  0.363
2004 Seo HC, Edvardsen RB, Maeland AD, Bjordal M, Jensen MF, Hansen A, Flaat M, Weissenbach J, Lehrach H, Wincker P, Reinhardt R, Chourrout D. Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica. Nature. 431: 67-71. PMID 15343333 DOI: 10.1038/Nature02709  0.308
2004 Rickert AM, Lehrach H, Sperling S. Multiplexed real-time PCR using universal reporters. Clinical Chemistry. 50: 1680-3. PMID 15331508 DOI: 10.1373/Clinchem.2004.034512  0.32
2004 Bauer O, Guerasimova A, Sauer S, Thamm S, Steinfath M, Herwig R, Janitz M, Lehrach H, Radelof U. Multiplexed hybridizations of positively charge-tagged peptide nucleic acids detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 18: 1821-9. PMID 15329876 DOI: 10.1002/Rcm.1554  0.303
2004 Volff JN, Lehrach H, Reinhardt R, Chourrout D. Retroelement dynamics and a novel type of chordate retrovirus-like element in the miniature genome of the tunicate Oikopleura dioica. Molecular Biology and Evolution. 21: 2022-33. PMID 15254255 DOI: 10.1093/Molbev/Msh207  0.337
2004 Kahlem P, Sultan M, Herwig R, Steinfath M, Balzereit D, Eppens B, Saran NG, Pletcher MT, South ST, Stetten G, Lehrach H, Reeves RH, Yaspo ML. Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome. Genome Research. 14: 1258-67. PMID 15231742 DOI: 10.1101/Gr.1951304  0.343
2004 Poustka AJ, Kühn A, Radosavljevic V, Wellenreuther R, Lehrach H, Panopoulou G. On the origin of the chordate central nervous system: expression of onecut in the sea urchin embryo. Evolution & Development. 6: 227-36. PMID 15230963 DOI: 10.1111/J.1525-142X.2004.04028.X  0.328
2004 Groth D, Lehrach H, Hennig S. GOblet: a platform for Gene Ontology annotation of anonymous sequence data. Nucleic Acids Research. 32: W313-7. PMID 15215401 DOI: 10.1093/Nar/Gkh406  0.348
2004 Quiring R, Wittbrodt B, Henrich T, Ramialison M, Burgtorf C, Lehrach H, Wittbrodt J. Large-scale expression screening by automated whole-mount in situ hybridization. Mechanisms of Development. 121: 971-6. PMID 15210201 DOI: 10.1016/J.Mod.2004.03.031  0.362
2004 Khorasani MZ, Hennig S, Imre G, Asakawa S, Palczewski S, Berger A, Hori H, Naruse K, Mitani H, Shima A, Lehrach H, Wittbrodt J, Kondoh H, Shimizu N, Himmelbauer H. A first generation physical map of the medaka genome in BACs essential for positional cloning and clone-by-clone based genomic sequencing. Mechanisms of Development. 121: 903-13. PMID 15210195 DOI: 10.1016/J.Mod.2004.03.024  0.369
2004 Krzywinski M, Wallis J, Gösele C, Bosdet I, Chiu R, Graves T, Hummel O, Layman D, Mathewson C, Wye N, Zhu B, Albracht D, Asano J, Barber S, Brown-John M, ... ... Lehrach H, et al. Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome. Genome Research. 14: 766-79. PMID 15060021 DOI: 10.1101/Gr.2336604  0.331
2004 Hurt P, Walter L, Sudbrak R, Klages S, Müller I, Shiina T, Inoko H, Lehrach H, Günther E, Reinhardt R, Himmelbauer H. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Genome Research. 14: 631-9. PMID 15060004 DOI: 10.1101/Gr.1987704  0.339
2004 Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, ... ... Lehrach H, et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 428: 493-521. PMID 15057822 DOI: 10.1038/Nature02426  0.358
2004 Angenendt P, Nyarsik L, Szaflarski W, Glökler J, Nierhaus KH, Lehrach H, Cahill DJ, Lueking A. Cell-free protein expression and functional assay in nanowell chip format. Analytical Chemistry. 76: 1844-9. PMID 15053642 DOI: 10.1021/Ac035114I  0.33
2004 Konthur Z, Adolph K, Burguera G, Sternjak A, Förster A, Lehrach H, Burmester G, Skriner K. Arthritis Research & Therapy. 6: 13. DOI: 10.1186/Ar1055  0.327
2003 Sakaki Y, Watanabe H, Taylor T, Hattori M, Fujiyama A, Toyoda A, Kuroki Y, Itoh T, Saitou N, Oota S, Kim CG, Kitano T, Lehrach H, Yaspo ML, Sudbrak R, et al. Human versus chimpanzee chromosome-wide sequence comparison and its evolutionary implication. Cold Spring Harbor Symposia On Quantitative Biology. 68: 455-60. PMID 15338648 DOI: 10.1101/Sqb.2003.68.455  0.325
2003 Hoehe MR, Timmermann B, Lehrach H. Human inter-individual DNA sequence variation in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics. Current Pharmaceutical Biotechnology. 4: 351-78. PMID 14683431 DOI: 10.2174/1389201033377300  0.377
2003 Kersten B, Feilner T, Kramer A, Wehrmeyer S, Possling A, Witt I, Zanor MI, Stracke R, Lueking A, Kreutzberger J, Lehrach H, Cahilll DJ. Generation of Arabidopsis protein chips for antibody and serum screening. Plant Molecular Biology. 52: 999-1010. PMID 14558660 DOI: 10.1023/A:1025424814739  0.317
2003 Grzeskowiak R, Witt H, Drungowski M, Thermann R, Hennig S, Perrot A, Osterziel KJ, Klingbiel D, Scheid S, Spang R, Lehrach H, Ruiz P. Expression profiling of human idiopathic dilated cardiomyopathy. Cardiovascular Research. 59: 400-11. PMID 12909323 DOI: 10.1016/S0008-6363(03)00426-7  0.362
2003 Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE. Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease. The Journal of Biological Chemistry. 278: 41452-61. PMID 12888569 DOI: 10.1074/Jbc.M303354200  0.532
2003 Hennig S, Groth D, Lehrach H. Automated Gene Ontology annotation for anonymous sequence data. Nucleic Acids Research. 31: 3712-5. PMID 12824400 DOI: 10.1093/Nar/Gkg582  0.35
2003 Panopoulou G, Hennig S, Groth D, Krause A, Poustka AJ, Herwig R, Vingron M, Lehrach H. New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes. Genome Research. 13: 1056-66. PMID 12799346 DOI: 10.1101/Gr.874803  0.372
2003 Kodzius R, Rhyner C, Konthur Z, Buczek D, Lehrach H, Walter G, Crameri R. Rapid identification of allergen-encoding cDNA clones by phage display and high-density arrays. Combinatorial Chemistry & High Throughput Screening. 6: 147-54. PMID 12678710 DOI: 10.2174/1386207033329751  0.336
2003 Greber B, Lehrach H, Himmelbauer H. Characterization of trimethylpsoralen as a mutagen for mouse embryonic stem cells. Mutation Research. 525: 67-76. PMID 12650906 DOI: 10.1016/S0027-5107(02)00316-0  0.322
2003 Malecová B, Ramser J, O'Brien JK, Janitz M, Júdová J, Lehrach H, Simúth J. Honeybee (Apis mellifera L.) mrjp gene family: computational analysis of putative promoters and genomic structure of mrjp1, the gene coding for the most abundant protein of larval food. Gene. 303: 165-75. PMID 12559578 DOI: 10.1016/S0378-1119(02)01174-5  0.382
2003 Sudbrak R, Reinhardt R, Hennig S, Lehrach H, Günther E, Walter L. Comparative and evolutionary analysis of the rhesus macaque extended MHC class II region. Immunogenetics. 54: 699-704. PMID 12557056 DOI: 10.1007/S00251-002-0515-Z  0.313
2002 Gitton Y, Dahmane N, Baik S, Ruiz i Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML. A gene expression map of human chromosome 21 orthologues in the mouse. Nature. 420: 586-90. PMID 12466855 DOI: 10.1038/Nature01270  0.394
2002 Eickhoff H, Konthur Z, Lueking A, Lehrach H, Walter G, Nordhoff E, Nyarsik L, Büssow K. Protein array technology: the tool to bridge genomics and proteomics. Advances in Biochemical Engineering/Biotechnology. 77: 103-12. PMID 12227733 DOI: 10.1007/3-540-45713-5_6  0.326
2002 Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R. DEFOG: a practical scheme for deciphering families of genes. Genomics. 80: 295-302. PMID 12213199 DOI: 10.1006/Geno.2002.6830  0.343
2002 Heiser V, Engemann S, Bröcker W, Dunkel I, Boeddrich A, Waelter S, Nordhoff E, Lurz R, Schugardt N, Rautenberg S, Herhaus C, Barnickel G, Böttcher H, Lehrach H, Wanker EE. Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay. Proceedings of the National Academy of Sciences of the United States of America. 99: 16400-6. PMID 12200548 DOI: 10.1073/Pnas.182426599  0.55
2002 Klose J, Nock C, Herrmann M, Stühler K, Marcus K, Blüggel M, Krause E, Schalkwyk LC, Rastan S, Brown SD, Büssow K, Himmelbauer H, Lehrach H. Genetic analysis of the mouse brain proteome. Nature Genetics. 30: 385-93. PMID 11912495 DOI: 10.1038/Ng861  0.349
2002 Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, ... ... Lehrach H, et al. The genome sequence of Schizosaccharomyces pombe. Nature. 415: 871-80. PMID 11859360 DOI: 10.1038/Nature724  0.387
2002 Olbrich H, Häffner K, Kispert A, Völkel A, Volz A, Sasmaz G, Reinhardt R, Hennig S, Lehrach H, Konietzko N, Zariwala M, Noone PG, Knowles M, Mitchison HM, Meeks M, et al. Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry. Nature Genetics. 30: 143-4. PMID 11788826 DOI: 10.1038/Ng817  0.316
2002 Fujiyama A, Watanabe H, Toyoda A, Taylor TD, Itoh T, Tsai SF, Park HS, Yaspo ML, Lehrach H, Chen Z, Fu G, Saitou N, Osoegawa K, de Jong PJ, Suto Y, et al. Construction and analysis of a human-chimpanzee comparative clone map. Science (New York, N.Y.). 295: 131-4. PMID 11778049 DOI: 10.1126/Science.1065199  0.353
2001 Lehrach H, Wanker EE. Huntington's disease: from gene to potential therapy. Dialogues in Clinical Neuroscience. 3: 17-23. PMID 22034471  0.497
2001 Herzel H, Beule D, Kielbasa S, Korbel J, Sers C, Malik A, Eickhoff H, Lehrach H, Schuchhardt J. Extracting information from cDNA arrays. Chaos (Woodbury, N.Y.). 11: 98-107. PMID 12779445 DOI: 10.1063/1.1336843  0.304
2001 Büssow K, Konthur Z, Lueking A, Lehrach H, Walter G. Protein array technology. Potential use in medical diagnostics. American Journal of Pharmacogenomics : Genomics-Related Research in Drug Development and Clinical Practice. 1: 37-43. PMID 12173313 DOI: 10.2165/00129785-200101010-00005  0.416
2001 Musa A, Lehrach H, Russo VA. Distinct expression patterns of two zebrafish homologues of the human APP gene during embryonic development. Development Genes and Evolution. 211: 563-7. PMID 11862463 DOI: 10.1007/S00427-001-0189-9  0.314
2001 Dickmeis T, Aanstad P, Clark M, Fischer N, Herwig R, Mourrain P, Blader P, Rosa F, Lehrach H, Strähle U. Identification of nodal signaling targets by array analysis of induced complex probes. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 222: 571-80. PMID 11748827 DOI: 10.1002/Dvdy.1220  0.332
2001 Schalkwyk LC, Cusack B, Dunkel I, Hopp M, Kramer M, Palczewski S, Piefke J, Scheel S, Weiher M, Wenske G, Lehrach H, Himmelbauer H. Advanced integrated mouse YAC map including BAC framework. Genome Research. 11: 2142-50. PMID 11731506 DOI: 10.1101/Gr.176201  0.379
2001 Herwig R, Aanstad P, Clark M, Lehrach H. Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments. Nucleic Acids Research. 29: E117. PMID 11726700 DOI: 10.1093/Nar/29.23.E117  0.341
2001 Nolte D, Ramser J, Niemann S, Lehrach H, Sudbrak R, Müller U. ACRC codes for a novel nuclear protein with unusual acidic repeat tract and maps to DYT3 (dystonia parkinsonism) critical interval in xq13.1. Neurogenetics. 3: 207-13. PMID 11714101 DOI: 10.1007/S100480100120  0.341
2001 Hemberger M, Cross JC, Ropers HH, Lehrach H, Fundele R, Himmelbauer H. UniGene cDNA array-based monitoring of transcriptome changes during mouse placental development. Proceedings of the National Academy of Sciences of the United States of America. 98: 13126-31. PMID 11698681 DOI: 10.1073/Pnas.231396598  0.362
2001 Holz C, Lueking A, Bovekamp L, Gutjahr C, Bolotina N, Lehrach H, Cahill DJ. A human cDNA expression library in yeast enriched for open reading frames. Genome Research. 11: 1730-5. PMID 11591650 DOI: 10.1101/Gr.181501  0.354
2001 Avner P, Bruls T, Poras I, Eley L, Gas S, Ruiz P, Wiles MV, Sousa-Nunes R, Kettleborough R, Rana A, Morissette J, Bentley L, Goldsworthy M, Haynes A, Herbert E, ... ... Lehrach H, et al. A radiation hybrid transcript map of the mouse genome. Nature Genetics. 29: 194-200. PMID 11586301 DOI: 10.1038/Ng1001-194  0.343
2001 Guerasimova A, Nyarsik L, Girnus I, Steinfath M, Wruck W, Griffiths H, Herwig R, Wierling C, O'Brien J, Eickhoff H, Lehrach H, Radelof U. New tools for oligonucleotide fingerprinting. Biotechniques. 31: 490-5. PMID 11570491 DOI: 10.2144/01313St01  0.316
2001 Waelter S, Scherzinger E, Hasenbank R, Nordhoff E, Lurz R, Goehler H, Gauss C, Sathasivam K, Bates GP, Lehrach H, Wanker EE. The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis. Human Molecular Genetics. 10: 1807-17. PMID 11532990 DOI: 10.1093/Hmg/10.17.1807  0.528
2001 Sittler A, Lurz R, Lueder G, Priller J, Lehrach H, Hayer-Hartl MK, Hartl FU, Wanker EE. Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease. Human Molecular Genetics. 10: 1307-15. PMID 11406612 DOI: 10.1093/Hmg/10.12.1307  0.527
2001 Waelter S, Boeddrich A, Lurz R, Scherzinger E, Lueder G, Lehrach H, Wanker EE. Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation. Molecular Biology of the Cell. 12: 1393-407. PMID 11359930 DOI: 10.1091/Mbc.12.5.1393  0.551
2001 Crameri R, Kodzius R, Konthur Z, Lehrach H, Blaser K, Walter G. Tapping allergen repertoires by advanced cloning technologies. International Archives of Allergy and Immunology. 124: 43-7. PMID 11306922 DOI: 10.1159/000053664  0.314
2001 Walter G, Konthur Z, Lehrach H. High-throughput screening of surface displayed gene products. Combinatorial Chemistry & High Throughput Screening. 4: 193-205. PMID 11281835 DOI: 10.2174/1386207013331228  0.361
2001 McPherson JD, Marra M, Hillier L, Waterston RH, Chinwalla A, Wallis J, Sekhon M, Wylie K, Mardis ER, Wilson RK, Fulton R, Kucaba TA, Wagner-McPherson C, Barbazuk WB, Gregory SG, ... ... Lehrach H, et al. A physical map of the human genome. Nature. 409: 934-41. PMID 11237014 DOI: 10.1038/35057157  0.337
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Lehrach H, et al. Initial sequencing and analysis of the human genome. Nature. 409: 860-921. PMID 11237011 DOI: 10.1038/35057062  0.326
2001 Brostjan C, Sobanov Y, Glienke J, Hayer S, Lehrach H, Francis F, Hofer E. The NKG2 natural killer cell receptor family: comparative analysis of promoter sequences. Genes and Immunity. 1: 504-8. PMID 11197693 DOI: 10.1038/Sj.Gene.6363715  0.311
2001 Bull C, Sobanov Y, Röhrdanz B, O'Brien J, Lehrach H, Hofer E. The centromeric part of the human NK gene complex: linkage of LOX-1 and LY49L with the CD94/NKG2 region. Genes and Immunity. 1: 280-7. PMID 11196705 DOI: 10.1038/Sj.Gene.6363678  0.366
2001 Buitkamp J, Kollers S, Durstewitz G, Welzel K, Schäfer K, Kellermann A, Lehrach H, Fries R. Construction and characterization of a gridded cattle BAC library. Animal Genetics. 31: 347-51. PMID 11167520 DOI: 10.1046/J.1365-2052.2000.00675.X  0.364
2001 Sudbrak R, Wieczorek G, Nuber UA, Mann W, Kirchner R, Erdogan F, Brown CJ, Wöhrle D, Sterk P, Kalscheuer VM, Berger W, Lehrach H, Ropers HH. X chromosome-specific cDNA arrays: identification of genes that escape from X-inactivation and other applications. Human Molecular Genetics. 10: 77-83. PMID 11136717 DOI: 10.1093/Hmg/10.1.77  0.343
2001 Lueking A, Konthur Z, Eickhoff H, Büssow K, Lehrach H, Cahill DJ. Protein microarrays - A tool for the post-genomic era Current Genomics. 2: 151-159. DOI: 10.2174/1389202013351039  0.408
2001 Avner P, Bruls T, Poras I, Eley L, Gas S, Ruiz P, Wiles MV, Sousa-Nunes R, Kettleborough R, Rana A, Morrisette J, Bentley L, Goldsworthy M, Haynes A, Herbert E, ... ... Lehrach H, et al. Erratum: A radiation hybrid transcript map of the mouse genome (Nature Genetics (2001) 29 (194-200)) Nature Genetics. 29: 352. DOI: 10.1038/Ng1101-352A  0.301
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, Fitzhugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Lehrach H, et al. Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921)) Nature. 412: 565-566. DOI: 10.1038/35087627  0.315
2000 Schubert M, Holland LZ, Panopoulou GD, Lehrach H, Holland ND. Characterization of amphioxus AmphiWnt8: insights into the evolution of patterning of the embryonic dorsoventral axis. Evolution & Development. 2: 85-92. PMID 11258394 DOI: 10.1046/J.1525-142X.2000.00047.X  0.318
2000 Lueking A, Holz C, Gotthold C, Lehrach H, Cahill D. A system for dual protein expression in Pichia pastoris and Escherichia coli. Protein Expression and Purification. 20: 372-8. PMID 11087676 DOI: 10.1006/Prep.2000.1317  0.334
2000 Gösele C, Hong L, Kreitler T, Rossmann M, Hieke B, Groß U, Kramer M, Himmelbauer H, Bihoreau MT, Kwitek-Black AE, Twigger S, Tonellato PJ, Jacob HJ, Schalkwyk LC, Lindpaintner K, ... ... Lehrach H, et al. High-throughput scanning of the rat genome using interspersed repetitive sequence-PCR markers Genomics. 69: 287-294. PMID 11056046 DOI: 10.1006/Geno.2000.6352  0.316
2000 Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG. Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mechanisms of Development. 98: 77-94. PMID 11044609 DOI: 10.1016/S0925-4773(00)00453-6  0.369
2000 Heinrich J, Bosse M, Eickhoff H, Nietfeld W, Reinhardt R, Lehrach H, Moelling K. Induction of putative tumor-suppressing genes Rat-1 fibroblasts by oncogenic Raf-1 as evidenced by robot-assisted complex hybridization Journal of Molecular Medicine. 78: 380-388. PMID 11043381 DOI: 10.1007/S001090000116  0.331
2000 Jakubiczka S, Mitulla B, Liehr T, Arnemann J, Lehrach H, Sudbrak R, Stumm M, Wieacker PF, Bettecken T. Incidental prenatal detection of an Xp deletion using an anonymous primer pair for fetal sexing Prenatal Diagnosis. 20: 842-846. PMID 11038467 DOI: 10.1002/1097-0223(200010)20:10<842::Aid-Pd915>3.0.Co;2-G  0.313
2000 Schreiber S, Hampe J, Eickhoff H, Lehrach H. Functional genomics in gastroenterology. Gut. 47: 601-7. PMID 11034570 DOI: 10.1136/Gut.47.5.601  0.355
2000 Cameron RA, Mahairas G, Rast JP, Martinez P, Biondi TR, Swartzell S, Wallace JC, Poustka AJ, Livingston BT, Wray GA, Ettensohn CA, Lehrach H, Britten RJ, Davidson EH, Hood L. A sea urchin genome project: sequence scan, virtual map, and additional resources. Proceedings of the National Academy of Sciences of the United States of America. 97: 9514-8. PMID 10920195 DOI: 10.1073/Pnas.160261897  0.374
2000 Egelhofer V, Büssow K, Luebbert C, Lehrach H, Nordhoff E. Improvements in protein identification by MALDI-TOF-MS peptide mapping. Analytical Chemistry. 72: 2741-50. PMID 10905302 DOI: 10.1021/Ac990686H  0.322
2000 Walter G, Büssow K, Cahill D, Lueking A, Lehrach H. Protein arrays for gene expression and molecular interaction screening. Current Opinion in Microbiology. 3: 298-302. PMID 10851162 DOI: 10.1016/S1369-5274(00)00093-X  0.351
2000 Hattori M, Fujiyama A, Taylor TD, Watanabe H, Yada T, Park HS, Toyoda A, Ishii K, Totoki Y, Choi DK, Groner Y, Soeda E, Ohki M, Takagi T, Sakaki Y, ... ... Lehrach H, et al. The DNA sequence of human chromosome 21. Nature. 405: 311-9. PMID 10830953 DOI: 10.1038/35012518  0.356
2000 Heiser V, Scherzinger E, Boeddrich A, Nordhoff E, Lurz R, Schugardt N, Lehrach H, Wanker EE. Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy. Proceedings of the National Academy of Sciences of the United States of America. 97: 6739-44. PMID 10829068 DOI: 10.1073/Pnas.110138997  0.545
2000 Büssow K, Nordhoff E, Lübbert C, Lehrach H, Walter G. A human cDNA library for high-throughput protein expression screening. Genomics. 65: 1-8. PMID 10777659 DOI: 10.1006/Geno.2000.6141  0.366
2000 Sudbrak R, Brown J, Dobson-Stone C, Carter S, Ramser J, White J, Healy E, Dissanayake M, Larrègue M, Perrussel M, Lehrach H, Munro CS, Strachan T, Burge S, Hovnanian A, et al. Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump. Human Molecular Genetics. 9: 1131-40. PMID 10767338 DOI: 10.1093/Hmg/9.7.1131  0.306
2000 Karabinos A, Riemer D, Panopoulou G, Lehrach H, Weber K. Characterisation and tissue-specific expression of the two keratin subfamilies of intermediate filament proteins in the cephalochordate Branchiostoma. European Journal of Cell Biology. 79: 17-26. PMID 10711422 DOI: 10.1078/S0171-9335(04)70003-5  0.318
2000 Wiles MV, Vauti F, Otte J, Füchtbauer EM, Ruiz P, Füchtbauer A, Arnold HH, Lehrach H, Metz T, Von Melchner H, Wurst W. Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells Nature Genetics. 24: 13-14. PMID 10615117 DOI: 10.1038/71622  0.313
2000 Hattori M, Fujiyama A, Taylor TD, Watanabe H, Yada T, Park H-, Toyoda A, Ishii K, Totoki Y, Choi D-, Groner Y, Soeda E, Ohki M, Takagi T, Sakaki Y, ... ... Lehrach H, et al. correction: The DNA sequence of human chromosome 21 Nature. 407: 110. DOI: 10.1038/35024135  0.315
2000 Knoblauch M, Gosele C, Zimdahl H, Hieke B, Himmelbauer H, Schalkwyk L, Lindpaintner K, Ganten D, Lehrach H. New tools for the high throughput characterization of rat genomic DNA samples Journal of Experimental Animal Science. 41: 35-37. DOI: 10.1016/S0939-8600(00)80024-3  0.344
1999 Starikov EB, Lehrach H, Wanker EE. Folding of oligoglutamines: a theoretical approach based upon thermodynamics and molecular mechanics. Journal of Biomolecular Structure & Dynamics. 17: 409-27. PMID 10636078 DOI: 10.1080/07391102.1999.10508374  0.511
1999 Himmelbauer H, Schalkwyk LC, Lehrach H. Interspersed repetitive sequence (IRS)-PCR for typing of whole genome radiation hybrid panels. Nucleic Acids Research. 28: e7. PMID 10606675 DOI: 10.1093/Nar/28.2.E7  0.347
1999 Wanker EE, Scherzinger E, Heiser V, Sittler A, Eickhoff H, Lehrach H. Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates. Methods in Enzymology. 309: 375-86. PMID 10507036 DOI: 10.1016/S0076-6879(99)09026-6  0.558
1999 Erber A, Riemer D, Hofemeister H, Bovenschulte M, Stick R, Panopoulou G, Lehrach H, Weber K. Characterization of the Hydra lamin and its gene: A molecular phylogeny of metazoan lamins. Journal of Molecular Evolution. 49: 260-71. PMID 10441677 DOI: 10.1007/Pl00006548  0.335
1999 Hollenbach B, Scherzinger E, Schweiger K, Lurz R, Lehrach H, Wanker EE. Aggregation of truncated GST-HD exon 1 fusion proteins containing normal range and expanded glutamine repeats. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 991-4. PMID 10434297 DOI: 10.1098/Rstb.1999.0450  0.553
1999 Hills D, Tracey S, Masabanda J, Fries R, Schalkwyk LC, Lehrach H, Miller JR, Williams JL. A bovine YAC library containing four- to five-fold genome equivalents Mammalian Genome. 10: 837-838. PMID 10430672 DOI: 10.1007/S003359901100  0.303
1999 Poustka AJ, Herwig R, Krause A, Hennig S, Meier-Ewert S, Lehrach H. Toward the gene catalogue of sea urchin development: the construction and analysis of an unfertilized egg cDNA library highly normalized by oligonucleotide fingerprinting. Genomics. 59: 122-33. PMID 10409423 DOI: 10.1006/Geno.1999.5852  0.347
1999 Mozo T, Dewar K, Dunn P, Ecker JR, Fischer S, Kloska S, Lehrach H, Marra M, Martienssen R, Meier-Ewert S, Altmann T. A complete BAC-based physical map of the Arabidopsis thaliana genome Nature Genetics. 22: 271-275. PMID 10391215 DOI: 10.1038/10334  0.322
1999 Zhu B, Smith JA, Tracey SM, Konfortov BA, Welzel K, Schalkwyk LC, Lehrach H, Kollers S, Masabanda J, Buitkamp J, Fries R, Williams JL, Miller JR. A 5x genome coverage bovine BAC library: production, characterization, and distribution. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 706-9. PMID 10384044 DOI: 10.1007/S003359901075  0.357
1999 Clark MD, Panopoulou GD, Cahill DJ, Büssow K, Lehrach H. Construction and analysis of arrayed cDNA libraries. Methods in Enzymology. 303: 205-33. PMID 10349647 DOI: 10.1016/S0076-6879(99)03015-3  0.423
1999 Nock C, Gauss C, Schalkwyk LC, Klose J, Lehrach H, Himmelbauer H. Technology development at the interface of proteome research and genomics: mapping nonpolymorphic proteins on the physical map of mouse chromosomes. Electrophoresis. 20: 1027-32. PMID 10344281 DOI: 10.1002/(Sici)1522-2683(19990101)20:4/5<1027::Aid-Elps1027>3.0.Co;2-I  0.398
1999 Lueking A, Horn M, Eickhoff H, Büssow K, Lehrach H, Walter G. Protein microarrays for gene expression and antibody screening. Analytical Biochemistry. 270: 103-11. PMID 10328771 DOI: 10.1006/Abio.1999.4063  0.36
1999 Gauss C, Kalkum M, Löwe M, Lehrach H, Klose J. Analysis of the mouse proteome. (I) brain proteins: Separation by two- dimensional electrophoresis and identification by mass spectrometry and genetic variation Electrophoresis. 20: 575-600. PMID 10217174 DOI: 10.1002/(Sici)1522-2683(19990301)20:3<575::Aid-Elps575>3.0.Co;2-3  0.324
1999 Boeddrich A, Burgtorf C, Francis F, Hennig S, Panopoulou G, Steffens C, Borzym K, Lehrach H. Sequence analysis of an amphioxus cosmid containing a gene homologous to members of the aldo-keto reductase gene superfamily. Gene. 230: 207-14. PMID 10216259 DOI: 10.1016/S0378-1119(99)00079-7  0.369
1999 Scherzinger E, Sittler A, Schweiger K, Heiser V, Lurz R, Hasenbank R, Bates GP, Lehrach H, Wanker EE. Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology. Proceedings of the National Academy of Sciences of the United States of America. 96: 4604-9. PMID 10200309 DOI: 10.1073/Pnas.96.8.4604  0.535
1999 Boeddrich A, Burgtorf C, Roest Crollius H, Hennig S, Bernot A, Clark M, Reinhardt R, Lehrach H, Francis F. Analysis of the spermine synthase gene region in Fugu rubripes, Tetraodon fluviatilis, and Danio rerio. Genomics. 57: 164-8. PMID 10191098 DOI: 10.1006/Geno.1998.5732  0.372
1999 Seranski P, Heiss NS, Dhorne-Pollet S, Radelof U, Korn B, Hennig S, Backes E, Schmidt S, Wiemann S, Schwarz CE, Lehrach H, Poustka A. Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes. Genomics. 56: 1-11. PMID 10036180 DOI: 10.1006/Geno.1998.5647  0.381
1999 Blechschmidt K, Schweiger M, Wertz K, Poulson R, Christensen HM, Rosenthal A, Lehrach H, Yaspo ML. The mouse Aire gene: comparative genomic sequencing, gene organization, and expression. Genome Research. 9: 158-66. PMID 10022980 DOI: 10.1101/Gr.9.2.158  0.391
1999 Rinderle C, Christensen HM, Schweiger S, Lehrach H, Yaspo ML. AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers. Human Molecular Genetics. 8: 277-90. PMID 9931335 DOI: 10.1093/Hmg/8.2.277  0.318
1999 Sobanov Y, Glienke J, Brostjan C, Lehrach H, Francis F, Hofer E. Linkage of the NKG2 and CD94 receptor genes to D12S77 in the human natural killer gene complex. Immunogenetics. 49: 99-105. PMID 9887346 DOI: 10.1007/S002510050468  0.342
1999 Mozo T, Fischer S, Meier-Ewert S, Lehrach H, Altmann T. Use of the IGF BAC library for physical mapping of the Arabidopsis thaliana genome. The Plant Journal : For Cell and Molecular Biology. 16: 377-84. PMID 9881158 DOI: 10.1046/J.1365-313X.1998.00299.X  0.357
1999 Leser U, Roest Crollius H, Lehrach H, Sudbrak R. IXDB, an X chromosome integrated database (update). Nucleic Acids Research. 27: 123-7. PMID 9847156 DOI: 10.1093/Nar/27.1.123  0.341
1999 Hildmann T, Kong X, O’Brien J, Riesselman L, Christensen H, Dagand E, Lehrach H, Yaspo M. A Contiguous 3-Mb Sequence-Ready Map in the S3–MX Region on 21q22.2 Based on High- Throughput Nonisotopic Library Screenings Genome Research. 9: 360-372. DOI: 10.1101/Gr.9.4.360  0.302
1998 Zechner U, Scheel S, Hemberger M, Hopp M, Haaf T, Fundele R, Wanker EE, Lehrach H, Wedemeyer N, Himmelbauer H. Characterization of the mouse Src homology 3 domain gene Sh3d2c on Chr 7 demonstrates coexpression with huntingtin in the brain and identifies the processed pseudogene Sh3d2c-ps1 on Chr 2. Genomics. 54: 505-10. PMID 9878254 DOI: 10.1006/Geno.1998.5584  0.589
1998 Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE. SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates. Molecular Cell. 2: 427-36. PMID 9809064 DOI: 10.1016/S1097-2765(00)80142-2  0.564
1998 Burgtorf C, Welzel K, Hasenbank R, Zehetner G, Weis S, Lehrach H. Gridded genomic libraries of different chordate species: a reference library system for basic and comparative genetic studies of chordate genomes. Genomics. 52: 230-2. PMID 9782092 DOI: 10.1006/Geno.1998.5444  0.315
1998 Büssow K, Cahill D, Nietfeld W, Bancroft D, Scherzinger E, Lehrach H, Walter G. A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library. Nucleic Acids Research. 26: 5007-8. PMID 9776767 DOI: 10.1093/Nar/26.21.5007  0.341
1998 Buitkamp J, Ewald D, Schalkwyk L, Weiher M, Masabanda J, Sazanov A, Lehrach H, Fries R. Construction and characterisation of a gridded chicken cosmid library with four-fold genomic coverage. Animal Genetics. 29: 295-301. PMID 9745668 DOI: 10.1046/J.1365-2052.1998.00331.X  0.352
1998 Schalkwyk LC, Weiher M, Kirby M, Cusack B, Himmelbauer H, Lehrach H. Refined radiation hybrid map of mouse Chromosome 17 Mammalian Genome. 9: 807-811. PMID 9745034 DOI: 10.1007/S003359900871  0.303
1998 Förnzler D, Her H, Knapik EW, Clark M, Lehrach H, Postlethwait JH, Zon LI, Beier DR. Gene mapping in zebrafish using single-strand conformation polymorphism analysis. Genomics. 51: 216-22. PMID 9722944 DOI: 10.1006/Geno.1998.5386  0.331
1998 Glienke J, Sobanov Y, Brostjan C, Steffens C, Nguyen C, Lehrach H, Hofer E, Francis F. The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex. Immunogenetics. 48: 163-73. PMID 9683661 DOI: 10.1007/S002510050420  0.358
1998 Himmelbauer H, Dunkel I, Otto GW, Burgtorf C, Schalkwyk LC, Lehrach H. Complex probes for high-throughput parallel genetic mapping of genomic mouse BAC clones. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 611-6. PMID 9680379 DOI: 10.1007/S003359900831  0.356
1998 Georgalis Y, Starikov EB, Hollenbach B, Lurz R, Scherzinger E, Saenger W, Lehrach H, Wanker EE. Huntingtin aggregation monitored by dynamic light scattering. Proceedings of the National Academy of Sciences of the United States of America. 95: 6118-21. PMID 9600927 DOI: 10.1073/Pnas.95.11.6118  0.511
1998 Kapanadze B, Kashuba V, Baranova A, Rasool O, Van Everdink W, Liu Y, Syomov A, Corcoran M, Poltaraus A, Brodyansky V, Syomova N, Kazakov A, Ibbotson R, Van Den Berg A, Gizatullin R, ... ... Lehrach H, et al. A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5 Febs Letters. 426: 266-270. PMID 9599022 DOI: 10.1016/S0014-5793(98)00357-3  0.362
1998 Bertaux F, Sharp AH, Ross CA, Lehrach H, Bates GP, Wanker E. HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice. Febs Letters. 426: 229-32. PMID 9599014 DOI: 10.1016/S0014-5793(98)00352-4  0.56
1998 Beye M, Poch A, Burgtorf C, Moritz RFA, Lehrach H. A gridded genomic library of the honeybee (Apis mellifera): A reference library system for basic and comparative genetic studies of a hymenopteran genome Genomics. 49: 317-320. PMID 9598322 DOI: 10.1006/Geno.1998.5253  0.328
1998 Newell W, Beck S, Lehrach H, Lyall A. Estimation of distances and map construction using radiation hybrids. Genome Research. 8: 493-508. PMID 9582193 DOI: 10.1101/Gr.8.5.493  0.303
1998 Tait D, Riccio M, Sittler A, Scherzinger E, Santi S, Ognibene A, Maraldi NM, Lehrach H, Wanker EE. Ataxin-3 is transported into the nucleus and associates with the nuclear matrix. Human Molecular Genetics. 7: 991-7. PMID 9580663 DOI: 10.1093/Hmg/7.6.991  0.561
1998 Yaspo ML, Aaltonen J, Horelli-Kuitunen N, Peltonen L, Lehrach H. Cloning of a novel human putative type Ia integral membrane protein mapping to 21q22.3. Genomics. 49: 133-6. PMID 9570958 DOI: 10.1006/Geno.1998.5217  0.403
1998 Groet J, Ives JH, South AP, Baptista PR, Jones TA, Yaspo ML, Lehrach H, Potier MC, Van Broeckhoven C, Nizetić D. Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome. Genome Research. 8: 385-98. PMID 9548974 DOI: 10.1101/Gr.8.4.385  0.348
1998 Dahmane N, Ghezala GA, Gosset P, Chamoun Z, Dufresne-Zacharia MC, Lopes C, Rabatel N, Gassanova-Maugenre S, Chettouh Z, Abramowski V, Fayet E, Yaspo ML, Korn B, Blouin JL, Lehrach H, et al. Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome. Genomics. 48: 12-23. PMID 9503011 DOI: 10.1006/Geno.1997.5146  0.336
1998 Rodríguez A, Carretero M, Glienke J, Bellón T, Ramírez A, Lehrach H, Francis F, López-Botet M. Structure of the human CD94 C-type lectin gene. Immunogenetics. 47: 305-309. PMID 9472066 DOI: 10.1007/S002510050362  0.302
1998 Lorenz B, Francis F, Gempel K, Böddrich A, Josten M, Schmahl W, Schmidt J, Lehrach H, Meitinger T, Strom TM. Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene. Human Molecular Genetics. 7: 541-7. PMID 9467015 DOI: 10.1093/Hmg/7.3.541  0.318
1998 Himmelbauer H, Wedemeyer N, Haaf T, Wanker EE, Schalkwyk LC, Lehrach H. IRS-PCR-based genetic mapping of the huntingtin interacting protein gene (HIP1) on mouse chromosome 5. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 26-31. PMID 9434941 DOI: 10.1007/S003359900674  0.589
1997 Pribill I, Barnes GT, Chen J, Church D, Buckler A, Baxendale S, Bates GP, Lehrach H, Gusella MJ, Duyao MP, Ambrose CM, Gusella JF, MacDonald ME. Exon trapping and sequence-based methods of gene finding in transcript mapping of human 4p16.3. Somatic Cell and Molecular Genetics. 23: 413-27. PMID 9661704 DOI: 10.1007/Bf02673751  0.394
1997 Wedemeyer N, Peoples R, Himmelbauer H, Lehrach H, Francke U, Wanker EE. Localization of the human HIP1 gene close to the elastin (ELN) locus on 7q11.23. Genomics. 46: 313-5. PMID 9417924 DOI: 10.1006/Geno.1997.5027  0.547
1997 Sathasivam K, Baxendale S, Mangiarini L, Bertaux F, Hetherington C, Kanazawa I, Lehrach H, Bates GP. Aberrant processing of the Fugu HD (FrHD) mRNA in mouse cells and in transgenic mice. Human Molecular Genetics. 6: 2141-9. PMID 9328479 DOI: 10.1093/Hmg/6.12.2141  0.395
1997 Gosset P, Ghezala GA, Korn B, Yaspo ML, Poutska A, Lehrach H, Sinet PM, Créau N. A new inward rectifier potassium channel gene (KCNJ15) localized on chromosome 21 in the Down syndrome chromosome region 1 (DCR1). Genomics. 44: 237-41. PMID 9299242 DOI: 10.1006/Geno.1997.4865  0.324
1997 Holland ND, Zhang SC, Clark M, Panopoulou G, Lehrach H, Holland LZ. Sequence and developmental expression of AmphiTob, an amphioxus homolog of vertebrate Tob in the PC3/BTG1/Tob family of tumor suppressor genes. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 210: 11-8. PMID 9286591 DOI: 10.1002/(Sici)1097-0177(199709)210:1<11::Aid-Aja2>3.0.Co;2-4  0.302
1997 Schweifer N, Valk PJ, Delwel R, Cox R, Francis F, Meier-Ewert S, Lehrach H, Barlow DP. Characterization of the C3 YAC contig from proximal mouse chromosome 17 and analysis of allelic expression of genes flanking the imprinted Igf2r gene. Genomics. 43: 285-97. PMID 9268631 DOI: 10.1006/Geno.1997.4816  0.364
1997 Scherzinger E, Lurz R, Turmaine M, Mangiarini L, Hollenbach B, Hasenbank R, Bates GP, Davies SW, Lehrach H, Wanker EE. Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo. Cell. 90: 549-58. PMID 9267034 DOI: 10.1016/S0092-8674(00)80514-0  0.549
1997 Ishikawa-Brush Y, Powell JF, Bolton P, Miller AP, Francis F, Willard HF, Lehrach H, Monaco AP. Autism and multiple exostoses associated with an X;8 translocation occurring within the GRPR gene and 3' to the SDC2 gene. Human Molecular Genetics. 6: 1241-50. PMID 9259269 DOI: 10.1093/Hmg/6.8.1241  0.346
1997 Francis F, Strom TM, Hennig S, Böddrich A, Lorenz B, Brandau O, Mohnike KL, Cagnoli M, Steffens C, Klages S, Borzym K, Pohl T, Oudet C, Econs MJ, Rowe PS, ... ... Lehrach H, et al. Genomic organization of the human PEX gene mutated in X-linked dominant hypophosphatemic rickets. Genome Research. 7: 573-85. PMID 9199930 DOI: 10.1101/Gr.7.6.573  0.307
1997 Wanker EE, Rovira C, Scherzinger E, Hasenbank R, Wälter S, Tait D, Colicelli J, Lehrach H. HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system. Human Molecular Genetics. 6: 487-95. PMID 9147654 DOI: 10.1093/Hmg/6.3.487  0.578
1997 Crnogorac-Jurcevic T, Brown JR, Lehrach H, Schalkwyk LC. Tetraodon fluviatilis, a new puffer fish model for genome studies Genomics. 41: 177-184. PMID 9143492 DOI: 10.1006/Geno.1997.4646  0.311
1997 Cai L, Schalkwyk LC, Schoeberlein-Stehli A, Zee RY, Smith A, Haaf T, Georges M, Lehrach H, Lindpaintner K. Construction and characterization of a 10-genome equivalent yeast artificial chromosome library for the laboratory rat, Rattus norvegicus. Genomics. 39: 385-92. PMID 9119376 DOI: 10.1006/Geno.1996.4494  0.351
1997 Rowe PSN, Oudet CL, Francis F, Sinding C, Pannetier S, Econs MJ, Strom TM, Meitinger T, Garabedian M, David A, Macher MA, Questiaux E, Popowska E, Pronicka E, Read AP, ... ... Lehrach H, et al. Distribution of mutations in the PEX gene in families with X-linked hypophosphataemic rickets (HYP) Human Molecular Genetics. 6: 539-549. PMID 9097956 DOI: 10.1093/Hmg/6.4.539  0.302
1997 Toye AA, Schalkwyk L, Lehrach H, Bumstead N. A yeast artificial chromosome (YAC) library containing 10 haploid chicken genome equivalents Mammalian Genome. 8: 274-276. PMID 9096109 DOI: 10.1007/S003359900408  0.362
1997 Lehrach H, Bancroft D, Maier E. Robotics, computing, and biology An interdisciplinary approach to the analysis of complex genomes Interdisciplinary Science Reviews. 22: 37-44. DOI: 10.1179/Isr.1997.22.1.37  0.344
1997 Maier E, Meier-Ewert S, Bancroft D, Lehrach H. Automated array technologies for gene expression profiling Drug Discovery Today. 2: 315-324. DOI: 10.1016/S1359-6446(97)01054-4  0.321
1996 Gregorová S, Mnuková-Fajdelová M, Trachtulec Z, Capková J, Loudová M, Hoglund M, Hamvas R, Lehrach H, Vincek V, Klein J, Forejt J. Sub-milliMorgan map of the proximal part of mouse Chromosome 17 including the hybrid sterility 1 gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 107-13. PMID 8835526 DOI: 10.1007/S003359900029  0.347
1996 Néri C, Albanèse V, Lebre AS, Holbert S, Saada C, Bougueleret L, Meier-Ewert S, Le Gall I, Millasseau P, Bui H, Giudicelli C, Massart C, Guillou S, Gervy P, Poullier E, ... ... Lehrach H, et al. Survey of CAG/CTG repeats in human cDNAs representing new genes: candidates for inherited neurological disorders. Human Molecular Genetics. 5: 1001-9. PMID 8817338 DOI: 10.1093/Hmg/5.7.1001  0.356
1996 Rowe PS, Goulding JN, Francis F, Oudet C, Econs MJ, Hanauer A, Lehrach H, Read AP, Mountford RC, Summerfield T, Weissenbach J, Fraser W, Drezner MK, Davies KE, O'Riordan JL. The gene for X-linked hypophosphataemic rickets maps to a 200-300kb region in Xp22.1, and is located on a single YAC containing a putative vitamin D response element (VDRE). Human Genetics. 97: 345-52. PMID 8786079 DOI: 10.1007/Bf02185769  0.353
1996 Osoegawa K, Susukida R, Okano S, Kato Y, Lehrach H, Nizetic D, Soeda E. Potential CpG-rich islands clustering around single-minded gene in Down syndrome chromosomal region Mammalian Genome. 7: 461-463. PMID 8662217 DOI: 10.1007/S003359900134  0.31
1996 Hummerich H, Lehrach H. Trinucleotide repeat expansion and human disease. Electrophoresis. 16: 1698-704. PMID 8582359 DOI: 10.1002/Elps.11501601282  0.311
1996 Ried K, Mertz A, Nagaraja R, Trusgnich M, Riley JH, Anand R, Lehrach H, Page D, Ellison JW, Rappold G. Characterization of a YAC contig spanning the pseudoautosomal region. Genomics. 29: 787-92. PMID 8575778 DOI: 10.1006/Geno.1995.9933  0.34
1995 Trachtulec Z, Vincek V, Hamvas RM, Forejt J, Lehrach H, Klein J. Physical map of mouse chromosome 17 in the region relevant for positional cloning of the Hybrid sterility 1 gene. Genomics. 23: 132-7. PMID 7829061 DOI: 10.1006/Geno.1994.1468  0.346
1995 Brown MA, Jones KA, Nicolai H, Bonjardim M, Black D, McFarlane R, de Jong P, Quirk JP, Lehrach H, Solomon E. Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1. Proceedings of the National Academy of Sciences of the United States of America. 92: 4362-6. PMID 7753812 DOI: 10.1073/Pnas.92.10.4362  0.385
1995 Yaspo ML, Gellen L, Mott R, Korn B, Nizetic D, Poustka AM, Lehrach H. Model for a transcript map of human chromosome 21: isolation of new coding sequences from exon and enriched cDNA libraries. Human Molecular Genetics. 4: 1291-304. PMID 7581366 DOI: 10.1093/Hmg/4.8.1291  0.397
1995 Francis F, Hennig S, Korn B, Reinhardt R, de Jong P, Poustka A, Lehrach H, Rowe PSN, Goulding JN, Summerfield T, Mountford R, Read AP, Popowska E, Pronicka E, Davies KE, et al. A gene (PEX) with homologies to endopeptidases is mutated in patients with X–linked hypophosphatemic rickets Nature Genetics. 11: 130-136. PMID 7550339 DOI: 10.1038/Ng1095-130  0.317
1995 Scholler P, Karger AE, Meier-Ewert S, Lehrach H, Delius H, Hoheisel JD. Fine-mapping of shotgun template-libraries; an efficient strategy for the systematic sequencing of genomic DNA. Nucleic Acids Research. 23: 3842-9. PMID 7479026 DOI: 10.1093/Nar/23.19.3842  0.336
1994 Vetrie D, Kendall E, Coffey A, Hassock S, Collins J, Todd C, Lehrach H, Bobrow M, Bentley DR, Harris A. A 6.5-Mb yeast artificial chromosome contig incorporating 33 DNA markers on the human X chromosome at Xq22. Genomics. 19: 42-7. PMID 8188239 DOI: 10.1006/Geno.1994.1010  0.348
1994 Hummerich H, Baxendale S, Mott R, Kirby SF, MacDonald ME, Gusella J, Lehrach H, Bates GP. Distribution of trinucleotide repeat sequences across a 2 Mbp region containing the Huntington's disease gene. Human Molecular Genetics. 3: 73-8. PMID 8162055 DOI: 10.1093/Hmg/3.1.73  0.328
1994 Cox RD, Shedlovsky A, Hamvas R, Goldsworthy M, Whittington J, Connelly CS, Dove WF, Lehrach H. A 1.2-Mb YAC Contig Spans the quaking Region Genomics. 21: 77-84. PMID 8088820 DOI: 10.1006/Geno.1994.1227  0.339
1994 Hagemann T, Surosky R, Monaco AP, Lehrach H, Rosen FS, Kwan SP. Physical mapping in a YAC contig of 11 markers on the human X chromosome in Xp11.23. Genomics. 21: 262-5. PMID 8088799 DOI: 10.1006/Geno.1994.1255  0.341
1994 Nižetić D, Gellen L, Hamvas RMJ, Mott R, Grigoriev A, Vatcheva R, Zehetner G, Yaspo ML, Dutriaux A, Lopes C, Delabar JM, Van Broeckhoven C, Potier MC, Lehrach H. An integrated YAC-overlap and 'cosmid-pocket' map of the human chromosome 21 Human Molecular Genetics. 3: 759-770. PMID 8081363 DOI: 10.1093/Hmg/3.5.759  0.33
1994 Francis F, Benham F, See CG, Fox M, Ishikawa-Brush Y, Monaco AP, Weiss B, Rappold G, Hamvas RM, Lehrach H. Identification of YAC and cosmid clones encompassing the ZFX-POLA region using irradiation hybrid cell lines. Genomics. 20: 75-83. PMID 8020959 DOI: 10.1006/Geno.1994.1129  0.351
1994 Siden TS, Kumlien J, Drumheller T, Smith SE, Röhme D, Lehrach H, Smith DI. Identification of human chromosome region 3p14.2–21.3-specific YAC clones using Alu-PCR products from a radiation hybrid Somatic Cell and Molecular Genetics. 20: 137-142. PMID 8009367 DOI: 10.1007/Bf02290683  0.327
1994 Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H. Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. Human Molecular Genetics. 3: 229-35. PMID 8004088 DOI: 10.1093/Hmg/3.2.229  0.344
1994 Höglund M, Aman P, Mandahl N, Lehrach H, Mitelman F. Isolation and regional localization of cosmid linking clones from human chromosome 12. Genomics. 21: 583-7. PMID 7959735 DOI: 10.1006/Geno.1994.1317  0.355
1994 Lengauer C, Henn T, Onyango P, Francis F, Lehrach H, Weith A. Large-scale isolation of human 1p36-specific P1 clones and their use for fluorescence in situ hybridization. Genetic Analysis, Techniques and Applications. 11: 140-7. PMID 7710779 DOI: 10.1016/1050-3862(94)90034-5  0.301
1994 Rotman G, Savitsky K, Ziv Y, Cole CG, Higgins MJ, Bar-Am I, Dunham I, Bar-Shira A, Vanagaite L, Qin S, Zhang J, Nowak NJ, Chandrasekharappa SC, Lehrach H, Avivi L, et al. A YAC contig spanning the ataxia-telangiectasia locus (groups A and C) at 11q22-q23. Genomics. 24: 234-42. PMID 7698744 DOI: 10.1006/Geno.1994.1611  0.346
1994 Breen M, Deakln L, Macdonald B, Miller S, Sibson R, Tarttelln E, Avner P, Bourgade F, Guenet J, Montagutelli X, Polrier C, Simon D, Tailor D, Bishop M, Kelly M, ... ... Lehrach H, et al. Towards high resolution maps of the mouse and human genomes—a facility for ordering markers to 0.1 cM resolution Human Molecular Genetics. 3: 621-627. DOI: 10.1093/Hmg/3.4.621  0.324
1994 Francis F, Zehetner G, Höglund M, Lehrach H. Construction and preliminary analysis of the ICRF human P1 library Genetic Analysis: Biomolecular Engineering. 11: 148-157. DOI: 10.1016/1050-3862(94)90035-3  0.324
1993 Heard E, Simmler MC, Larin Z, Rougeulle C, Courtier B, Lehrach H, Avner P. Physical mapping and YAC contig analysis of the region surrounding Xist on the mouse X chromosome. Genomics. 15: 559-69. PMID 8468050 DOI: 10.1006/Geno.1993.1108  0.338
1993 Hamvas RM, Larin Z, Brockdorff N, Rastan S, Lehrach H, Chartier FL, Brown SD. YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome. Genomics. 17: 52-8. PMID 8406471 DOI: 10.1006/Geno.1993.1282  0.326
1993 Tommerup N, Aagaard L, Lund CL, Boel E, Baxendale S, Bates GP, Lehrach H, Vissing H. A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome. Human Molecular Genetics. 2: 1571-5. PMID 8268908 DOI: 10.1093/Hmg/2.10.1571  0.358
1993 Cox RD, Meier-Ewert S, Ross M, Larin Z, Monaco AP, Lehrach H. Genome mapping and cloning of mutations using yeast artificial chromosomes Methods in Enzymology. 225: 637-653. PMID 8231876 DOI: 10.1016/0076-6879(93)25041-Y  0.314
1993 Larin Z, Monaco AP, Meier-Ewert S, Lehrach H. Construction and characterization of yeast artificial chromosome libraries from the mouse genome. Methods in Enzymology. 225: 623-37. PMID 8231875 DOI: 10.1016/0076-6879(93)25040-9  0.326
1993 Hadano S, Ishida Y, Bates GP, Nagayama T, Kanazawa I, Lehrach H, Ikeda J. Generation of high-density DNA markers from yeast artificial chromosome DNA by single unique primer-polymerase chain reaction. Genetic Analysis, Techniques and Applications. 10: 105-8. PMID 8204302 DOI: 10.1016/1050-3862(93)90032-E  0.325
1993 North MA, Sanseau P, Buckler AJ, Church D, Jackson A, Patel K, Trowsdale J, Lehrach H. Efficiency and specificity of gene isolation by exon amplification Mammalian Genome. 4: 466-474. PMID 8118096 DOI: 10.1007/Bf00364779  0.373
1993 Halford S, Wadey R, Roberts C, Daw SCM, Whiting JA, O'Donnell H, Dunham I, Bentley D, Lindsay E, BaldInI A, Francis F, Lehrach H, Williamson R, Wilson DI, Goodship J, et al. Isolation of a putative transcriptional regulator from the region of 22q11 deleted in DiGeorge syndrome, Shprintzen syndrome and familial congenital heart disease Human Molecular Genetics. 2: 2099-2107. PMID 8111380 DOI: 10.1093/Hmg/2.12.2099  0.337
1993 Cox RD, Whittington J, Shedlovsky A, Connelly CS, Dove WF, Goldsworthy M, Larin Z, Lehrach H. Detailed physical and genetic mapping in the region of plasminogen, D17Rp17e, and quaking Mammalian Genome. 4: 687-694. PMID 8111116 DOI: 10.1007/Bf00357791  0.314
1993 Korn B, Sedlacek Z, Manca A, Kioschis P, Konecki D, Lehrach H, Poustka A. A strategy for the selection of transcribed sequences in the Xq28 region. Human Molecular Genetics. 1: 235-42. PMID 1303192 DOI: 10.1093/Hmg/1.4.235  0.389
1992 Lennon GG, Lehrach H. Gene database for the fission yeast Schizosaccharomyces pombe. Current Genetics. 21: 1-11. PMID 1735122 DOI: 10.1007/Bf00318646  0.348
1992 Baldini A, Ross M, Nizetic D, Vatcheva R, Lindsay EA, Lehrach H, Siniscalco M. Chromosomal assignment of human YAC clones by fluorescence in situ hybridization: use of single-yeast-colony PCR and multiple labeling. Genomics. 14: 181-4. PMID 1427825 DOI: 10.1016/S0888-7543(05)80303-9  0.34
1992 Ambrose C, James M, Barnes G, Lin C, Bates G, Altherr M, Duyao M, Groot N, Church D, Wasmuth JJ, Lehrach H, Housman D, Buckler A, Gusella JF, MacDonald ME. A novel G protein-coupled receptor kinase gene cloned from 4p16.3 Human Molecular Genetics. 1: 697-703. PMID 1338872 DOI: 10.1093/Hmg/1.9.697  0.338
1992 Knight JC, Reeves BR, Kearney L, Monaco AP, Lehrach H, Cooper CS. Localization of the synovial sarcoma t(X;18)(p11.2;q11.2) breakpoint by fluorescence in situ hybridization. Human Molecular Genetics. 1: 633-7. PMID 1338692 DOI: 10.1093/Hmg/1.8.633  0.309
1991 Monaco AP, Lam VM, Zehetner G, Lennon GG, Douglas C, Nizetic D, Goodfellow PN, Lehrach H. Mapping irradiation hybrids to cosmid and yeast artificial chromosome libraries by direct hybridization of Alu-PCR products. Nucleic Acids Research. 19: 3315-8. PMID 2062647 DOI: 10.1093/Nar/19.12.3315  0.32
1991 Larin Z, Monaco AP, Lehrach H. Yeast artificial chromosome libraries containing large inserts from mouse and human DNA. Proceedings of the National Academy of Sciences of the United States of America. 88: 4123-7. PMID 2034658 DOI: 10.1073/Pnas.88.10.4123  0.336
1991 Nizetić D, Zehetner G, Monaco AP, Gellen L, Young BD, Lehrach H. Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries. Proceedings of the National Academy of Sciences of the United States of America. 88: 3233-7. PMID 2014245 DOI: 10.1073/Pnas.88.8.3233  0.316
1991 Drmanac R, Nizetic D, Lennon GG, Beitverda A, Lehrach H. W (A or T) sequences as probes and primers suitable for genomic mapping and fingerprinting. Nucleic Acids Research. 19: 5839-42. PMID 1945873 DOI: 10.1093/Nar/19.21.5839  0.334
1991 Patel K, Cox R, Shipley J, Kiely F, Frazer K, Cox DR, Lehrach H, Sheer D. A novel and rapid method for isolating sequences adjacent to rare cutting sites and their use in physical mapping. Nucleic Acids Research. 19: 4371-5. PMID 1886764 DOI: 10.1093/Nar/19.16.4371  0.322
1991 MacDonald ME, Scott HS, Whaley WL, Pohl T, Wasmuth JJ, Lehrach H, Morris CP, Frischauf AM, Hopwood JJ, Gusella JF. Huntington disease-linked locus D4S111 exposed as the alpha-L-iduronidase gene. Somatic Cell and Molecular Genetics. 17: 421-5. PMID 1832239 DOI: 10.1007/Bf01233067  0.345
1991 Nadeau JH, Herrmann B, Bucan M, Burkart D, Crosby JL, Erhart MA, Kosowsky M, Kraus JP, Michiels F, Schnattinger A, Tchetgen MB, Varnum D, Willison K, Lehrach H, Barlow D. Genetic maps of mouse Chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci Genomics. 9: 78-89. PMID 1672293 DOI: 10.1016/0888-7543(91)90223-2  0.313
1990 Herrmann BG, Labeit S, Poustka A, King TR, Lehrach H. Cloning of the T gene required in mesoderm formation in the mouse Nature. 343: 617-622. PMID 2154694 DOI: 10.1038/343617A0  0.32
1989 Youngman S, Sarfarazi M, Bucan M, MacDonald M, Smith B, Zimmer M, Gilliam C, Frischauf AM, Wasmuth JJ, Gusella JF, Lehrach H, Harper PS, Shaw DJ. A new DNA marker (D4S90) is located terminally on the short arm of chromosome 4, close to the Huntington disease gene Genomics. 5: 802-809. PMID 2574148 DOI: 10.1016/0888-7543(89)90122-5  0.327
1989 Nguyen C, Poustka AM, Djabali M, Roux D, Mattei JF, Lehrach H, Jordan BR. Large-scale mapping and chromosome jumping in the q27 region of the human X chromosome. Genomics. 5: 298-303. PMID 2571578 DOI: 10.1016/0888-7543(89)90061-X  0.318
1989 Herrmann B, Wilkinson D, Bhatt S, Labeit S, Poustka A, King T, Lehrach H. Molecular cloning and expression of the mouse Brachyury (T) gene Cell Differentiation and Development. 27: 168. DOI: 10.1016/0922-3371(89)90516-9  0.311
1988 Michiels F, Craig AG, Zehetner G, Smith GP, Lehrach H. Molecular approaches to genome analysis: a strategy for the construction of ordered overlapping clone libraries. Computer Applications in the Biosciences : Cabios. 3: 203-10. PMID 3453229 DOI: 10.1093/Bioinformatics/3.3.203  0.335
1988 Burmeister M, Monaco AP, Gillard EF, van Ommen GJ, Affara NA, Ferguson-Smith MA, Kunkel LM, Lehrach H. A 10-megabase physical map of human Xp21, including the Duchenne muscular dystrophy gene. Genomics. 2: 189-202. PMID 3397058 DOI: 10.1016/0888-7543(88)90002-X  0.326
1988 Burmeister M, Lehrach H. Jekyll, a family of phage-plasmid shuttle vectors. Gene. 73: 245-50. PMID 2854093 DOI: 10.1016/0378-1119(88)90331-9  0.303
1988 Labeit S, Lehrach H, Goody RS. DNA sequencing using alpha-thiodeoxynucleotides. Methods in Enzymology. 155: 166-77. PMID 2828863 DOI: 10.1016/0076-6879(87)55015-7  0.308
1988 Frischauf AM, Murray N, Lehrach H. Lambda phage vectors--EMBL series. Methods in Enzymology. 153: 103-15. PMID 2828839 DOI: 10.1016/0076-6879(87)53051-8  0.322
1988 Poustka A, Lehrach H. Chromosome Jumping: A Long Range Cloning Technique Genetic Engineering. 10: 169-193. DOI: 10.1007/978-1-4615-7081-3_10  0.358
1987 Barlow DP, Bućan M, Lehrach H, Hogan BL, Gough NM. Close genetic and physical linkage between the murine haemopoietic growth factor genes GM-CSF and Multi-CSF (IL3) Embo Journal. 6: 617-623. PMID 3034600 DOI: 10.1002/J.1460-2075.1987.Tb04799.X  0.326
1987 Poustka A, Pohl TM, Barlow DP, Frischauf AM, Lehrach H. Construction and use of human chromosome jumping libraries from NotI-digested DNA. Nature. 325: 353-5. PMID 3027567 DOI: 10.1038/325353A0  0.372
1987 Herrmann BG, Barlow DP, Lehrach H. A large inverted duplication allows homologous recombination between chromosomes heterozygous for the proximal t complex inversion. Cell. 48: 813-25. PMID 2880670 DOI: 10.1016/0092-8674(87)90078-X  0.317
1987 Rappold GA, Stubbs L, Labeit S, Crkvenjakov RB, Lehrach H. Identification of a testis-specific gene from the mouse t-complex next to a CpG-rich island. The Embo Journal. 6: 1975-1980. DOI: 10.1002/J.1460-2075.1987.Tb02460.X  0.376
1986 Rackwitz HR, Zehetner G, Murialdo H, Delius H, Chai JH, Poustka A, Frischauf A, Lehrach H. Analysis of cosmids using linearization by phage lambda terminase. Gene. 40: 259-66. PMID 3007292 DOI: 10.1016/0378-1119(85)90048-4  0.328
1986 Poustka A, Lehrach H. Jumping libraries and linking libraries: the next generation of molecular tools in mammalian genetics Trends in Genetics. 2: 174-179. DOI: 10.1016/0168-9525(86)90219-2  0.367
1986 Bućan M, Yang-Feng T, Colberg-Poley A, Wolgemuth D, Guenet J, Francke U, Lehrach H. Genetic and cytogenetic localisation of the homeo box containing genes on mouse chromosome 6 and human chromosome 7. The Embo Journal. 5: 2899-2905. DOI: 10.1002/J.1460-2075.1986.Tb04585.X  0.332
1985 Müller G, Scherer G, Zentgraf H, Ruppert S, Herrmann B, Lehrach H, Schütz G. Isolation, characterization and chromosomal mapping of the mouse tyrosine aminotransferase gene. Journal of Molecular Biology. 184: 367-373. PMID 2413215 DOI: 10.1016/0022-2836(85)90287-6  0.394
1984 Röhme D, Fox H, Herrmann B, Frischauf AM, Edström JE, Mains P, Silver LM, Lehrach H. Molecular clones of the mouse t complex derived from microdissected metaphase chromosomes. Cell. 36: 783-8. PMID 6697397 DOI: 10.1016/0092-8674(84)90358-1  0.344
1984 Timm B, Kondor-Koch C, Lehrach H, Riedel H, Edström JE, Garoff H. Expression of viral membrane proteins from cloned cDNA by microinjection into eukaryotic cell nuclei. Methods in Enzymology. 96: 496-511. PMID 6318022 DOI: 10.1016/S0076-6879(83)96043-3  0.331
1984 Frischauf AM, Lehrach H, Poustka A, Murray N. Lambda replacement vectors carrying polylinker sequences. Journal of Molecular Biology. 170: 827-42. PMID 6315951 DOI: 10.1016/S0022-2836(83)80190-9  0.343
1984 Silver LM, Garrels JI, Lehrach H. Molecular studies of mouse chromosome 17 and the T complex Genetic Engineering. 6: 141-156. DOI: 10.1007/978-1-4684-4793-4_8  0.315
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