| Year |
Citation |
Score |
| 2024 |
Aziz F, Reddy K, Fernandez Vega V, Dey R, Hicks KA, Rao S, Jordan LO, Smith E, Shumate J, Scampavia L, Carpino N, Spicer TP, French JB. Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins. Journal of Medicinal Chemistry. PMID 38252624 DOI: 10.1021/acs.jmedchem.3c01763 |
0.564 |
|
| 2022 |
Monticone G, Huang Z, Csibi F, Leit S, Ciccone D, Champhekar AS, Austin JE, Ucar DA, Hossain F, Ibba SV, Boulares AH, Carpino N, Xu K, Majumder S, Osborne BA, et al. Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses. Frontiers in Immunology. 13: 987298. PMID 36090975 DOI: 10.3389/fimmu.2022.987298 |
0.313 |
|
| 2020 |
Parashar K, Carpino N. A role for the Sts phosphatases in negatively regulating IFNγ-mediated production of nitric oxide in monocytes. Immunity, Inflammation and Disease. PMID 32841534 DOI: 10.1002/Iid3.336 |
0.456 |
|
| 2018 |
Zhou W, Yin Y, Smith E, Chou J, Shumate J, Scampavia L, Spicer T, Carpino N, French JB. Discovery and Characterization of Two Classes of Selective Inhibitors of the Suppressor of TCR Signaling Family of Proteins. Acs Infectious Diseases. PMID 30485744 DOI: 10.1021/Acsinfecdis.8B00238 |
0.462 |
|
| 2017 |
Parashar K, Kopping E, Frank D, Sampath V, Thanassi DG, Carpino N. Increased resistance to intradermal Francisella tularensis LVS infection by inactivation of the Sts phosphatases. Infection and Immunity. PMID 28630061 DOI: 10.1128/Iai.00406-17 |
0.338 |
|
| 2017 |
Zhou W, Yin Y, Carpino N, French J. Phosphatase suppressor of T-cell receptor signaling pathway Acta Crystallographica Section a Foundations and Advances. 73: a69-a69. DOI: 10.1107/S0108767317099317 |
0.623 |
|
| 2016 |
Ivanova E, Carpino N. Negative regulation of TCR signaling by ubiquitination of Zap-70 Lys-217. Molecular Immunology. 73: 19-28. PMID 27032069 DOI: 10.1016/j.molimm.2016.03.006 |
0.677 |
|
| 2014 |
Newman TN, Liverani E, Ivanova E, Russo GL, Carpino N, Ganea D, Safadi F, Kunapuli SP, Tsygankov AY. Members of the novel UBASH3/STS/TULA family of cellular regulators suppress T-cell-driven inflammatory responses in vivo. Immunology and Cell Biology. 92: 837-50. PMID 25047644 DOI: 10.1038/Icb.2014.60 |
0.52 |
|
| 2014 |
Cieniewicz B, Carpino N, Krug LT. Enhanced response of T cells from murine gammaherpesvirus 68-infected mice lacking the suppressor of T cell receptor signaling molecules Sts-1 and Sts-2. Plos One. 9: e90196. PMID 24587276 DOI: 10.1371/Journal.Pone.0090196 |
0.515 |
|
| 2014 |
Luis BS, Carpino N. Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants Febs Journal. 281: 696-707. PMID 24256567 DOI: 10.1111/febs.12615 |
0.689 |
|
| 2013 |
San Luis B, Nassar N, Carpino N. New insights into the catalytic mechanism of histidine phosphatases revealed by a functionally essential arginine residue within the active site of the Sts phosphatases. The Biochemical Journal. 453: 27-35. PMID 23565972 DOI: 10.1042/BJ20121769 |
0.53 |
|
| 2013 |
Back SH, Adapala NS, Barbe MF, Carpino NC, Tsygankov AY, Sanjay A. TULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast function. Cellular and Molecular Life Sciences : Cmls. 70: 1269-84. PMID 23149425 DOI: 10.1007/S00018-012-1203-2 |
0.318 |
|
| 2011 |
San Luis B, Sondgeroth B, Nassar N, Carpino N. Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways. The Journal of Biological Chemistry. 286: 15943-54. PMID 21393235 DOI: 10.1074/Jbc.M110.177634 |
0.536 |
|
| 2010 |
Thomas DH, Getz TM, Newman TN, Dangelmaier CA, Carpino N, Kunapuli SP, Tsygankov AY, Daniel JL. A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets. Blood. 116: 2570-8. PMID 20585042 DOI: 10.1182/Blood-2010-02-268136 |
0.369 |
|
| 2010 |
Jakoncic J, Sondgeroth B, Carpino N, Nassar N. The 1.35 A resolution structure of the phosphatase domain of the suppressor of T-cell receptor signaling protein in complex with sulfate. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 643-7. PMID 20516590 DOI: 10.1107/S1744309110014259 |
0.552 |
|
| 2009 |
Carpino N, Chen Y, Nassar N, Oh HW. The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways. Molecular Immunology. 46: 3224-31. PMID 19733910 DOI: 10.1016/J.Molimm.2009.08.015 |
0.642 |
|
| 2009 |
Chen Y, Jakoncic J, Parker KA, Carpino N, Nassar N. Structures of the phosphorylated and VO(3)-bound 2H-phosphatase domain of Sts-2. Biochemistry. 48: 8129-35. PMID 19627098 DOI: 10.1021/Bi9008648 |
0.478 |
|
| 2009 |
Chen Y, Jakoncic J, Carpino N, Nassar N. Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity. Biochemistry. 48: 1681-90. PMID 19196006 DOI: 10.1021/Bi802219N |
0.672 |
|
| 2008 |
Chen Y, Jakoncic J, Wang J, Zheng X, Carpino N, Nassar N. Structural and functional characterization of the c-terminal domain of the ecdysteroid phosphate phosphatase from bombyx mori reveals a new enzymatic activity. Biochemistry. 47: 12135-45. PMID 18937503 DOI: 10.1021/Bi801318W |
0.45 |
|
| 2008 |
Takahashi Y, Takahashi M, Carpino N, Jou ST, Chao JR, Tanaka S, Shigeyoshi Y, Parganas E, Ihle JN. Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway. Molecular Endocrinology (Baltimore, Md.). 22: 1673-81. PMID 18451094 DOI: 10.1210/Me.2008-0058 |
0.465 |
|
| 2008 |
Agrawal R, Carpino N, Tsygankov A. TULA proteins regulate activity of the protein tyrosine kinase Syk. Journal of Cellular Biochemistry. 104: 953-64. PMID 18189269 DOI: 10.1002/Jcb.21678 |
0.426 |
|
| 2007 |
Collingwood TS, Smirnova EV, Bogush M, Carpino N, Annan RS, Tsygankov AY. T-cell ubiquitin ligand affects cell death through a functional interaction with apoptosis-inducing factor, a key factor of caspase-independent apoptosis. The Journal of Biological Chemistry. 282: 30920-8. PMID 17709377 DOI: 10.1074/Jbc.M706870200 |
0.459 |
|
| 2007 |
Mikhailik A, Ford B, Keller J, Chen Y, Nassar N, Carpino N. A phosphatase activity of Sts-1 contributes to the suppression of TCR signaling. Molecular Cell. 27: 486-97. PMID 17679096 DOI: 10.1016/J.Molcel.2007.06.015 |
0.725 |
|
| 2004 |
Carpino N, Thierfelder WE, Chang MS, Saris C, Turner SJ, Ziegler SF, Ihle JN. Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development. Molecular and Cellular Biology. 24: 2584-92. PMID 14993294 DOI: 10.1128/MCB.24.6.2584-2592.2004 |
0.398 |
|
| 2004 |
Carpino N, Turner S, Mekala D, Takahashi Y, Zang H, Geiger TL, Doherty P, Ihle JN. Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2. Immunity. 20: 37-46. PMID 14738763 DOI: 10.1016/S1074-7613(03)00351-0 |
0.71 |
|
| 2003 |
Takahashi Y, Carpino N, Cross JC, Torres M, Parganas E, Ihle JN. SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. The Embo Journal. 22: 372-84. PMID 12554639 DOI: 10.1093/Emboj/Cdg057 |
0.393 |
|
| 2002 |
Jou ST, Carpino N, Takahashi Y, Piekorz R, Chao JR, Carpino N, Wang D, Ihle JN. Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex. Molecular and Cellular Biology. 22: 8580-91. PMID 12446777 DOI: 10.1128/Mcb.22.24.8580-8591.2002 |
0.45 |
|
| 2000 |
Kashige N, Carpino N, Kobayashi R. Tyrosine phosphorylation of p62(dok) by p210(bcr-abl) inhibits RasGAP activity Proceedings of the National Academy of Sciences of the United States of America. 97: 2093-2098. PMID 10688886 DOI: 10.1073/pnas.040547997 |
0.315 |
|
| 2000 |
Wang D, Moriggl R, Stravopodis D, Carpino N, Marine JC, Teglund S, Feng J, Ihle JN. A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5. The Embo Journal. 19: 392-9. PMID 10654938 DOI: 10.1093/Emboj/19.3.392 |
0.395 |
|
| 1997 |
Clarkson BD, Strife A, Wisniewski D, Lambek C, Carpino N. New understanding of the pathogenesis of CML: A prototype of early neoplasia Leukemia. 11: 1404-1428. PMID 9305592 |
0.431 |
|
| 1997 |
Carpino N, Wisniewski D, Strife A, Marshak D, Kobayashi R, Stillman B, Clarkson B. p62(dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells Cell. 88: 197-204. PMID 9008160 DOI: 10.1016/S0092-8674(00)81840-1 |
0.319 |
|
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